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MCL coexpression mm9:2326: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0019855;calcium channel inhibitor activity;0.0268556468270756;20907!GO:0008200;ion channel inhibitor activity;0.0268556468270756;20907!GO:0016248;channel inhibitor activity;0.0268556468270756;20907!GO:0005246;calcium channel regulator activity;0.0268556468270756;20907!GO:0004683;calmodulin-dependent protein kinase activity;0.0268556468270756;207565!GO:0016247;channel regulator activity;0.0268556468270756;20907!GO:0015457;auxiliary transport protein activity;0.0268556468270756;20907!GO:0000149;SNARE binding;0.0268556468270756;20907!GO:0004672;protein kinase activity;0.0268556468270756;22174,207565!GO:0017156;calcium ion-dependent exocytosis;0.0282399074109683;20907!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0298844870419492;22174,207565!GO:0016301;kinase activity;0.0447116880677966;22174,207565!GO:0006836;neurotransmitter transport;0.0499513795386572;20907!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.0499513795386572;22174,207565!
}}
}}

Revision as of 13:11, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr2:119625278..119625308,+p1@Tyro3
Mm9::chr2:119625310..119625328,+p4@Tyro3
Mm9::chr5:123229287..123229443,-p1@Camkk2
Mm9::chr5:135516995..135517035,+p2@Stx1a


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019855calcium channel inhibitor activity0.0268556468270756
GO:0008200ion channel inhibitor activity0.0268556468270756
GO:0016248channel inhibitor activity0.0268556468270756
GO:0005246calcium channel regulator activity0.0268556468270756
GO:0004683calmodulin-dependent protein kinase activity0.0268556468270756
GO:0016247channel regulator activity0.0268556468270756
GO:0015457auxiliary transport protein activity0.0268556468270756
GO:0000149SNARE binding0.0268556468270756
GO:0004672protein kinase activity0.0268556468270756
GO:0017156calcium ion-dependent exocytosis0.0282399074109683
GO:0016773phosphotransferase activity, alcohol group as acceptor0.0298844870419492
GO:0016301kinase activity0.0447116880677966
GO:0006836neurotransmitter transport0.0499513795386572
GO:0016772transferase activity, transferring phosphorus-containing groups0.0499513795386572



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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