MCL coexpression mm9:3446

Phase1 CAGE Peaks

	Short description
Mm9::chr4:107838037..107838046,+	p2@Echdc2
Mm9::chr4:107838054..107838129,+	p1@Echdc2
Mm9::chr8:3467617..3467662,-	p1@Pex11c

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016559	peroxisome fission	0.0083267138672151
GO:0048285	organelle fission	0.0083267138672151
GO:0031903	microbody membrane	0.0130783834579628
GO:0005778	peroxisomal membrane	0.0130783834579628
GO:0044439	peroxisomal part	0.0130783834579628
GO:0044438	microbody part	0.0130783834579628
GO:0007031	peroxisome organization and biogenesis	0.0130783834579628
GO:0042579	microbody	0.0406146964366407
GO:0005777	peroxisome	0.0406146964366407

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
epithelial cell	1.02e-07	25

Uber Anatomy

Ontology term	p-value	n
trunk region element	5.15e-14	79
immaterial anatomical entity	3.28e-13	79
trunk	5.65e-12	90
subdivision of trunk	1.21e-08	66
exocrine gland	2.45e-08	25
exocrine system	2.45e-08	25
digestive tract diverticulum	2.16e-07	23
sac	2.16e-07	23
liver	3.72e-07	22
epithelial sac	3.72e-07	22
digestive gland	3.72e-07	22
epithelium of foregut-midgut junction	3.72e-07	22
anatomical boundary	3.72e-07	22
hepatobiliary system	3.72e-07	22
foregut-midgut junction	3.72e-07	22
hepatic diverticulum	3.72e-07	22
liver primordium	3.72e-07	22
septum transversum	3.72e-07	22
liver bud	3.72e-07	22
anatomical space	3.84e-07	57
epithelial tube	5.43e-07	47
pancreas	5.52e-07	12

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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