MCL coexpression mm9:1043: Difference between revisions
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|ontology_enrichment_uberon= | |ontology_enrichment_uberon= | ||
|tfbs_overrepresentation_for_novel_motifs=0.438063,0.369498,0.411716,0.480627,0.299217,0.495263,0.587291,0.206208,0.215218,0.478312,0.542749,0.575086,0.206435,0.599731,0.315771,0,1.86712,0.291368,0.561256,0.731589,0.374752,0.27937,0.598814,0.80655,1.07577,0.62766,0.184473,0.516511,0.344372,0.876948,0.50223,0.897561,0.78719,0.498917,0.316253,0.248902,0.766323,0.57142,0.258564,0.230656,0.800988,0.507468,0.0742755,0.317766,0.515031,0.469348,0.714592,0.532496,0.0609361,0.347313,0.777641,1.57618,0.431711,1.04034,1.0579,0.606984,0.356236,0.56214,0.176152,1.47148,0.877332,0.664501,0.226529,0.766235,1.49952,0.807219,1.19497,1.54543,0.872612,1.39786,1.01778,0.21183,0.611537,1.09164,0.507615,0.482617,0.166511,0.703064,0.859987,0.378988,0.212973,0.812889,0.663039,0.200155,0.975495,1.84334,0.374181,0.145788,0.719558,1.70793,1.26498,0.980512,0.910485,0.305079,0.708155,0.237542,0.203879,0.913319,0.71485,0.399703,0.7665,0.897279,2.33242,0.778243,0.777175,1.26443,0.837607,0.528416,0.383871,0.982279,1.10097,1.02459,0.380122,1.35148,1.27206,0.293461,0.735764,0.484437,1.86983,0.276329,1.09707,0.745011,0.629509,0.702145,1.32639,0.863723,0.595563,2.08944,2.67845,0.308038,1.00568,0.473246,1.16374,0.620831,1.29374,0.0806013,1.13474,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,0.448938,0.300961,0.886471,0.927167,1.04192,0.243291,0.619892,1.12411,0.655955,0.327731,0.435579,0.446272,1.25393,0.974632,0.864173,1.09603,0.767269,0.612377,0.278874,0.573477,0.0907999 | |tfbs_overrepresentation_for_novel_motifs=0.438063,0.369498,0.411716,0.480627,0.299217,0.495263,0.587291,0.206208,0.215218,0.478312,0.542749,0.575086,0.206435,0.599731,0.315771,0,1.86712,0.291368,0.561256,0.731589,0.374752,0.27937,0.598814,0.80655,1.07577,0.62766,0.184473,0.516511,0.344372,0.876948,0.50223,0.897561,0.78719,0.498917,0.316253,0.248902,0.766323,0.57142,0.258564,0.230656,0.800988,0.507468,0.0742755,0.317766,0.515031,0.469348,0.714592,0.532496,0.0609361,0.347313,0.777641,1.57618,0.431711,1.04034,1.0579,0.606984,0.356236,0.56214,0.176152,1.47148,0.877332,0.664501,0.226529,0.766235,1.49952,0.807219,1.19497,1.54543,0.872612,1.39786,1.01778,0.21183,0.611537,1.09164,0.507615,0.482617,0.166511,0.703064,0.859987,0.378988,0.212973,0.812889,0.663039,0.200155,0.975495,1.84334,0.374181,0.145788,0.719558,1.70793,1.26498,0.980512,0.910485,0.305079,0.708155,0.237542,0.203879,0.913319,0.71485,0.399703,0.7665,0.897279,2.33242,0.778243,0.777175,1.26443,0.837607,0.528416,0.383871,0.982279,1.10097,1.02459,0.380122,1.35148,1.27206,0.293461,0.735764,0.484437,1.86983,0.276329,1.09707,0.745011,0.629509,0.702145,1.32639,0.863723,0.595563,2.08944,2.67845,0.308038,1.00568,0.473246,1.16374,0.620831,1.29374,0.0806013,1.13474,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,0.448938,0.300961,0.886471,0.927167,1.04192,0.243291,0.619892,1.12411,0.655955,0.327731,0.435579,0.446272,1.25393,0.974632,0.864173,1.09603,0.767269,0.612377,0.278874,0.573477,0.0907999 | ||
|tfbs_overrepresentation_jaspar=MA0003.1;0.188259,MA0004.1;0.481116,MA0006.1;1.51462,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;0.222567,MA0017.1;0.337808,MA0019.1;0.740036,MA0024.1;2.04116,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;2.35736,MA0029.1;0.858105,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;0.801219,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.362005,MA0056.1;0,MA0057.1;0.376102,MA0058.1;1.00014,MA0059.1;0.397033,MA0060.1;1.90283,MA0061.1;0.261749,MA0063.1;0,MA0066.1;0.616444,MA0067.1;1.27078,MA0068.1;0.121435,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;0.519509,MA0072.1;0.927016,MA0073.1;0.0210304,MA0074.1;0.580087,MA0076.1;0.938908,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;1.07783,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;0.598004,MA0089.1;0,MA0090.1;0.446539,MA0091.1;0.494398,MA0092.1;0.446857,MA0093.1;0.879104,MA0095.1;0,MA0098.1;0,MA0100.1;0.568369,MA0101.1;0.406019,MA0103.1;0.348572,MA0105.1;0.162418,MA0106.1;0.677988,MA0107.1;0.342432,MA0108.2;0.763162,MA0109.1;0,MA0111.1;0.460823,MA0113.1;0.649407,MA0114.1;0.259463,MA0115.1;1.0246,MA0116.1;0.311187,MA0117.1;0.992087,MA0119.1;0.40661,MA0122.1;1.01209,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;1.74348,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.585936,MA0140.1;0.568252,MA0141.1;0.368264,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.262477,MA0145.1;0.631666,MA0146.1;0.493711,MA0147.1;0.753844,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;2.93496,MA0035.2;0.573016,MA0039.2;1.72008,MA0138.2;0.727395,MA0002.2;0.205289,MA0137.2;0.365364,MA0104.2;1.17226,MA0047.2;0.626803,MA0112.2;0.0910939,MA0065.2;0.0914071,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.126143,MA0155.1;0.102995,MA0156.1;0.936991,MA0157.1;0.781683,MA0158.1;0,MA0159.1;0.776527,MA0160.1;0.50056,MA0161.1;0,MA0162.1;1.26636,MA0163.1;0.116706,MA0164.1;0.600609,MA0080.2;0.908823,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;0.323753,MA0102.2;1.65195,MA0258.1;0.246285,MA0259.1;0.729797,MA0442.1;0 | |||
}} | }} |
Revision as of 12:43, 23 January 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0000375 | RNA splicing, via transesterification reactions | 0.00366088563816577 |
GO:0000398 | nuclear mRNA splicing, via spliceosome | 0.00366088563816577 |
GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 0.00366088563816577 |
GO:0000351 | assembly of spliceosomal tri-snRNP U4/U6.U5 | 0.0157720689898799 |
GO:0006374 | nuclear mRNA splicing via U2-type spliceosome | 0.0157720689898799 |
GO:0000387 | spliceosomal snRNP biogenesis | 0.0157720689898799 |
GO:0000244 | assembly of spliceosomal tri-snRNP | 0.0157720689898799 |
GO:0005681 | spliceosome | 0.0157720689898799 |
GO:0007067 | mitosis | 0.0157720689898799 |
GO:0007049 | cell cycle | 0.0157720689898799 |
GO:0000087 | M phase of mitotic cell cycle | 0.0157720689898799 |
GO:0008380 | RNA splicing | 0.0157720689898799 |
GO:0046540 | U4/U6 x U5 tri-snRNP complex | 0.0157720689898799 |
GO:0000278 | mitotic cell cycle | 0.0207318967750936 |
GO:0006397 | mRNA processing | 0.0207318967750936 |
GO:0000279 | M phase | 0.0207318967750936 |
GO:0051301 | cell division | 0.0207318967750936 |
GO:0016071 | mRNA metabolic process | 0.0229934679448512 |
GO:0030532 | small nuclear ribonucleoprotein complex | 0.023320273436187 |
GO:0022403 | cell cycle phase | 0.023320273436187 |
GO:0031202 | RNA splicing factor activity, transesterification mechanism | 0.023405844151925 |
GO:0005634 | nucleus | 0.0319252401371916 |
GO:0006396 | RNA processing | 0.0330509239918394 |
GO:0006402 | mRNA catabolic process | 0.0476614567240531 |
GO:0030529 | ribonucleoprotein complex | 0.0487217682126219 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.188259 |
MA0004.1 | 0.481116 |
MA0006.1 | 1.51462 |
MA0007.1 | 0.465969 |
MA0009.1 | 0.92425 |
MA0014.1 | 0.222567 |
MA0017.1 | 0.337808 |
MA0019.1 | 0.740036 |
MA0024.1 | 2.04116 |
MA0025.1 | 1.15921 |
MA0027.1 | 2.57545 |
MA0028.1 | 2.35736 |
MA0029.1 | 0.858105 |
MA0030.1 | 0.864739 |
MA0031.1 | 0.828781 |
MA0038.1 | 0.62758 |
MA0040.1 | 0.936879 |
MA0041.1 | 0.404721 |
MA0042.1 | 0.391504 |
MA0043.1 | 1.02178 |
MA0046.1 | 0.960497 |
MA0048.1 | 0.801219 |
MA0050.1 | 0.520357 |
MA0051.1 | 0.636645 |
MA0052.1 | 0.945011 |
MA0055.1 | 0.362005 |
MA0056.1 | 0 |
MA0057.1 | 0.376102 |
MA0058.1 | 1.00014 |
MA0059.1 | 0.397033 |
MA0060.1 | 1.90283 |
MA0061.1 | 0.261749 |
MA0063.1 | 0 |
MA0066.1 | 0.616444 |
MA0067.1 | 1.27078 |
MA0068.1 | 0.121435 |
MA0069.1 | 0.945354 |
MA0070.1 | 0.93557 |
MA0071.1 | 0.519509 |
MA0072.1 | 0.927016 |
MA0073.1 | 0.0210304 |
MA0074.1 | 0.580087 |
MA0076.1 | 0.938908 |
MA0077.1 | 0.905143 |
MA0078.1 | 0.670113 |
MA0081.1 | 1.07783 |
MA0083.1 | 1.02098 |
MA0084.1 | 1.59945 |
MA0087.1 | 0.977537 |
MA0088.1 | 0.598004 |
MA0089.1 | 0 |
MA0090.1 | 0.446539 |
MA0091.1 | 0.494398 |
MA0092.1 | 0.446857 |
MA0093.1 | 0.879104 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.568369 |
MA0101.1 | 0.406019 |
MA0103.1 | 0.348572 |
MA0105.1 | 0.162418 |
MA0106.1 | 0.677988 |
MA0107.1 | 0.342432 |
MA0108.2 | 0.763162 |
MA0109.1 | 0 |
MA0111.1 | 0.460823 |
MA0113.1 | 0.649407 |
MA0114.1 | 0.259463 |
MA0115.1 | 1.0246 |
MA0116.1 | 0.311187 |
MA0117.1 | 0.992087 |
MA0119.1 | 0.40661 |
MA0122.1 | 1.01209 |
MA0124.1 | 1.21735 |
MA0125.1 | 1.14291 |
MA0130.1 | 0 |
MA0131.1 | 1.74348 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.05845 |
MA0136.1 | 0.600242 |
MA0139.1 | 0.585936 |
MA0140.1 | 0.568252 |
MA0141.1 | 0.368264 |
MA0142.1 | 0.814115 |
MA0143.1 | 0.665982 |
MA0144.1 | 0.262477 |
MA0145.1 | 0.631666 |
MA0146.1 | 0.493711 |
MA0147.1 | 0.753844 |
MA0148.1 | 0.49752 |
MA0149.1 | 0.411562 |
MA0062.2 | 2.93496 |
MA0035.2 | 0.573016 |
MA0039.2 | 1.72008 |
MA0138.2 | 0.727395 |
MA0002.2 | 0.205289 |
MA0137.2 | 0.365364 |
MA0104.2 | 1.17226 |
MA0047.2 | 0.626803 |
MA0112.2 | 0.0910939 |
MA0065.2 | 0.0914071 |
MA0150.1 | 0.465855 |
MA0151.1 | 0 |
MA0152.1 | 0.626912 |
MA0153.1 | 1.07519 |
MA0154.1 | 0.126143 |
MA0155.1 | 0.102995 |
MA0156.1 | 0.936991 |
MA0157.1 | 0.781683 |
MA0158.1 | 0 |
MA0159.1 | 0.776527 |
MA0160.1 | 0.50056 |
MA0161.1 | 0 |
MA0162.1 | 1.26636 |
MA0163.1 | 0.116706 |
MA0164.1 | 0.600609 |
MA0080.2 | 0.908823 |
MA0018.2 | 0.610433 |
MA0099.2 | 0.721008 |
MA0079.2 | 0.323753 |
MA0102.2 | 1.65195 |
MA0258.1 | 0.246285 |
MA0259.1 | 0.729797 |
MA0442.1 | 0 |