MCL coexpression mm9:1876: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
Line 7: | Line 7: | ||
|ontology_enrichment_uberon=UBERON:0000468!5.76e-08!333 | |ontology_enrichment_uberon=UBERON:0000468!5.76e-08!333 | ||
|tfbs_overrepresentation_for_novel_motifs=0.641384,0.801438,0.612053,0.688265,0.483253,0.704257,1.88411,0.370124,1.76086,0.162942,0.755749,0.790506,0.96877,0.81685,0.502646,0,1.02248,0.473993,0.352304,0.24402,0.570433,0.197567,0.815872,0.481455,1.50428,0.846564,0.342316,0.727368,0.535752,0.290745,0.711848,1.12823,0.471365,0.854272,0.503207,0.30022,0.460474,0.786577,0.434783,0.40068,0.478558,0.717547,0.185353,0.504971,0.66772,0.675898,0.938241,0.744678,0.162985,0.539131,1.0041,0.875451,0.771943,1.2746,1.29252,0.82458,0.549352,0.776619,0.331485,0.822375,1.10737,0.885556,0.39557,0.992216,0.8366,1.03484,1.43193,1.78579,1.1025,1.63712,0.590754,0.377213,0.205546,1.32691,0.323563,0.310084,3.2365,0.926147,1.08947,0.575233,0.37865,1.04072,0.884013,0.362446,1.20828,0.11855,0.129654,1.4408,0.943446,1.94914,1.50286,1.21342,1.14153,0.490141,0.430015,0.409166,0.367176,1.14445,0.938512,0.264911,0.460566,1.12793,1.25667,1.00472,1.00361,0.717061,1.06633,1.75347,0.580757,0.57247,0.633483,2.80991,0.576517,0.7614,1.51002,0.476467,0.442329,0.692434,2.33456,0.456123,1.33244,0.970073,0.848526,0.925183,1.56496,1.09333,0.812403,1.13449,1.43038,0.493609,1.23918,0.680176,1.40022,0.839311,1.53196,0.195549,1.56752,0.719099,1.482,2.31884,1.91709,1.43673,0.861473,1.1391,2.27949,2.86517,0.941555,2.27909,0.653418,0.485304,0.293812,0.184289,1.27621,0.416214,0.838313,1.35996,0.87653,0.516549,0.63863,0.650472,3.27965,1.20739,1.09379,0.630949,0.993294,0.830321,0.459159,0.788782,0.992915 | |tfbs_overrepresentation_for_novel_motifs=0.641384,0.801438,0.612053,0.688265,0.483253,0.704257,1.88411,0.370124,1.76086,0.162942,0.755749,0.790506,0.96877,0.81685,0.502646,0,1.02248,0.473993,0.352304,0.24402,0.570433,0.197567,0.815872,0.481455,1.50428,0.846564,0.342316,0.727368,0.535752,0.290745,0.711848,1.12823,0.471365,0.854272,0.503207,0.30022,0.460474,0.786577,0.434783,0.40068,0.478558,0.717547,0.185353,0.504971,0.66772,0.675898,0.938241,0.744678,0.162985,0.539131,1.0041,0.875451,0.771943,1.2746,1.29252,0.82458,0.549352,0.776619,0.331485,0.822375,1.10737,0.885556,0.39557,0.992216,0.8366,1.03484,1.43193,1.78579,1.1025,1.63712,0.590754,0.377213,0.205546,1.32691,0.323563,0.310084,3.2365,0.926147,1.08947,0.575233,0.37865,1.04072,0.884013,0.362446,1.20828,0.11855,0.129654,1.4408,0.943446,1.94914,1.50286,1.21342,1.14153,0.490141,0.430015,0.409166,0.367176,1.14445,0.938512,0.264911,0.460566,1.12793,1.25667,1.00472,1.00361,0.717061,1.06633,1.75347,0.580757,0.57247,0.633483,2.80991,0.576517,0.7614,1.51002,0.476467,0.442329,0.692434,2.33456,0.456123,1.33244,0.970073,0.848526,0.925183,1.56496,1.09333,0.812403,1.13449,1.43038,0.493609,1.23918,0.680176,1.40022,0.839311,1.53196,0.195549,1.56752,0.719099,1.482,2.31884,1.91709,1.43673,0.861473,1.1391,2.27949,2.86517,0.941555,2.27909,0.653418,0.485304,0.293812,0.184289,1.27621,0.416214,0.838313,1.35996,0.87653,0.516549,0.63863,0.650472,3.27965,1.20739,1.09379,0.630949,0.993294,0.830321,0.459159,0.788782,0.992915 | ||
|tfbs_overrepresentation_jaspar=MA0003.1;1.34944,MA0004.1;0.6888,MA0006.1;0.497533,MA0007.1;0.672186,MA0009.1;1.15569,MA0014.1;0.581929,MA0017.1;0.528196,MA0019.1;0.964875,MA0024.1;1.11019,MA0025.1;1.39562,MA0027.1;2.81824,MA0028.1;0.509589,MA0029.1;1.08753,MA0030.1;1.09438,MA0031.1;1.05719,MA0038.1;0.846479,MA0040.1;1.16866,MA0041.1;0.604221,MA0042.1;0.589368,MA0043.1;1.25564,MA0046.1;1.1929,MA0048.1;0.266382,MA0050.1;1.73541,MA0051.1;0.856094,MA0052.1;1.17701,MA0055.1;0.125758,MA0056.1;0,MA0057.1;2.80216,MA0058.1;1.4226,MA0059.1;0.59559,MA0060.1;0.403071,MA0061.1;0.438628,MA0063.1;0,MA0066.1;1.94802,MA0067.1;1.50873,MA0068.1;0.256913,MA0069.1;1.17737,MA0070.1;1.16732,MA0071.1;0.73062,MA0072.1;1.15853,MA0073.1;8.63716,MA0074.1;0.795862,MA0076.1;0.550092,MA0077.1;1.13603,MA0078.1;0.891476,MA0081.1;0.621611,MA0083.1;1.25482,MA0084.1;1.84013,MA0087.1;1.21037,MA0088.1;1.1032,MA0089.1;0,MA0090.1;0.650768,MA0091.1;0.703314,MA0092.1;0.651119,MA0093.1;1.29026,MA0095.1;0,MA0098.1;0,MA0100.1;0.783305,MA0101.1;0.605676,MA0103.1;0.540576,MA0105.1;0.841866,MA0106.1;0.899777,MA0107.1;0.533522,MA0108.2;0.989014,MA0109.1;0,MA0111.1;0.666525,MA0113.1;0.869608,MA0114.1;0.43587,MA0115.1;1.25852,MA0116.1;0.497293,MA0117.1;1.22527,MA0119.1;0.606338,MA0122.1;1.24573,MA0124.1;1.45461,MA0125.1;1.37907,MA0130.1;0,MA0131.1;0.960068,MA0132.1;0,MA0133.1;0,MA0135.1;1.29308,MA0136.1;0.817395,MA0139.1;0.365453,MA0140.1;0.78318,MA0141.1;0.563066,MA0142.1;1.04199,MA0143.1;0.887119,MA0144.1;0.439506,MA0145.1;0.21199,MA0146.1;0.313734,MA0147.1;0.453952,MA0148.1;0.706718,MA0149.1;0.611881,MA0062.2;0.319836,MA0035.2;0.788288,MA0039.2;0.45096,MA0138.2;0.951653,MA0002.2;0.368961,MA0137.2;0.559766,MA0104.2;0.386166,MA0047.2;0.845655,MA0112.2;0.211985,MA0065.2;0.212467,MA0150.1;0.67206,MA0151.1;0,MA0152.1;0.84577,MA0153.1;1.31015,MA0154.1;0.728853,MA0155.1;1.21457,MA0156.1;0.549102,MA0157.1;2.30294,MA0158.1;0,MA0159.1;0.465802,MA0160.1;0.71003,MA0161.1;0,MA0162.1;0.346529,MA0163.1;3.61171,MA0164.1;0.817786,MA0080.2;0.534538,MA0018.2;0.828253,MA0099.2;0.944966,MA0079.2;9.08066,MA0102.2;1.8929,MA0258.1;0.419871,MA0259.1;0.441366,MA0442.1;0 | |||
}} | }} |
Revision as of 14:00, 23 January 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr10:126778639..126778670,- | p3@Gli1 |
Mm9::chr10:126778916..126778974,- | p1@Gli1 |
Mm9::chr10:126779021..126779032,- | p2@Gli1 |
Mm9::chr13:63674708..63674738,- | p1@Ptch1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0007224 | smoothened signaling pathway | 0.000383498602969375 |
GO:0009953 | dorsal/ventral pattern formation | 0.000458067775768976 |
GO:0048732 | gland development | 0.000913430094021413 |
GO:0003002 | regionalization | 0.00272177480718542 |
GO:0043109 | regulation of smoothened activity | 0.00291319800441589 |
GO:0048598 | embryonic morphogenesis | 0.00291319800441589 |
GO:0035295 | tube development | 0.00291319800441589 |
GO:0007389 | pattern specification process | 0.00336672667248463 |
GO:0007418 | ventral midline development | 0.00336672667248463 |
GO:0005113 | patched binding | 0.00336672667248463 |
GO:0060032 | notochord regression | 0.00336672667248463 |
GO:0060033 | anatomical structure regression | 0.00462912235634527 |
GO:0048570 | notochord morphogenesis | 0.00529028061488478 |
GO:0021938 | smoothened signaling pathway in regulation of granule cell precursor cell proliferation | 0.00529028061488478 |
GO:0009790 | embryonic development | 0.0067420677676526 |
GO:0021937 | Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation | 0.00685664389347801 |
GO:0009887 | organ morphogenesis | 0.00685664389347801 |
GO:0030903 | notochord development | 0.00685664389347801 |
GO:0015485 | cholesterol binding | 0.00685664389347801 |
GO:0008158 | hedgehog receptor activity | 0.00685664389347801 |
GO:0040015 | negative regulation of multicellular organism growth | 0.00685664389347801 |
GO:0021940 | positive regulation of granule cell precursor proliferation | 0.00685664389347801 |
GO:0021936 | regulation of granule cell precursor proliferation | 0.00685664389347801 |
GO:0021534 | cell proliferation in hindbrain | 0.00685664389347801 |
GO:0009954 | proximal/distal pattern formation | 0.00685664389347801 |
GO:0021924 | cell proliferation in the external granule layer | 0.00685664389347801 |
GO:0021930 | granule cell precursor proliferation | 0.00685664389347801 |
GO:0007399 | nervous system development | 0.00690808382009827 |
GO:0008589 | regulation of smoothened signaling pathway | 0.00766010646861597 |
GO:0032934 | sterol binding | 0.00835976554417887 |
GO:0021696 | cerebellar cortex morphogenesis | 0.00835976554417887 |
GO:0021587 | cerebellum morphogenesis | 0.0086767510059229 |
GO:0021575 | hindbrain morphogenesis | 0.00897449448372583 |
GO:0021695 | cerebellar cortex development | 0.00951885273914528 |
GO:0021983 | pituitary gland development | 0.00951885273914528 |
GO:0021536 | diencephalon development | 0.010282147655304 |
GO:0048562 | embryonic organ morphogenesis | 0.0105041764495005 |
GO:0030879 | mammary gland development | 0.0106411477768241 |
GO:0022037 | metencephalon development | 0.0106411477768241 |
GO:0021549 | cerebellum development | 0.0106411477768241 |
GO:0045926 | negative regulation of growth | 0.0112837374470277 |
GO:0009653 | anatomical structure morphogenesis | 0.0148410287656804 |
GO:0048568 | embryonic organ development | 0.0159179525336601 |
GO:0030902 | hindbrain development | 0.0176559464142327 |
GO:0008017 | microtubule binding | 0.0184936621275853 |
GO:0005496 | steroid binding | 0.0184936621275853 |
GO:0048513 | organ development | 0.0184936621275853 |
GO:0035270 | endocrine system development | 0.0184936621275853 |
GO:0040014 | regulation of multicellular organism growth | 0.0195162687051387 |
GO:0001841 | neural tube formation | 0.0195162687051387 |
GO:0015631 | tubulin binding | 0.0195162687051387 |
GO:0001839 | neural plate morphogenesis | 0.0195162687051387 |
GO:0001840 | neural plate development | 0.0195162687051387 |
GO:0001838 | embryonic epithelial tube formation | 0.0195162687051387 |
GO:0008201 | heparin binding | 0.0196770816090132 |
GO:0035264 | multicellular organism growth | 0.0196770816090132 |
GO:0030326 | embryonic limb morphogenesis | 0.0196770816090132 |
GO:0035113 | embryonic appendage morphogenesis | 0.0196770816090132 |
GO:0030324 | lung development | 0.0196770816090132 |
GO:0030323 | respiratory tube development | 0.0196770816090132 |
GO:0021915 | neural tube development | 0.0196770816090132 |
GO:0016485 | protein processing | 0.0196770816090132 |
GO:0016331 | morphogenesis of embryonic epithelium | 0.0209617737932445 |
GO:0048731 | system development | 0.0209617737932445 |
GO:0005539 | glycosaminoglycan binding | 0.0209617737932445 |
GO:0035107 | appendage morphogenesis | 0.0209617737932445 |
GO:0035108 | limb morphogenesis | 0.0209617737932445 |
GO:0060173 | limb development | 0.02115589848994 |
GO:0048736 | appendage development | 0.02115589848994 |
GO:0030247 | polysaccharide binding | 0.0213804384406477 |
GO:0001871 | pattern binding | 0.0221178296671192 |
GO:0008270 | zinc ion binding | 0.0236848855557652 |
GO:0003682 | chromatin binding | 0.0246230452223987 |
GO:0048856 | anatomical structure development | 0.0246230452223987 |
GO:0030900 | forebrain development | 0.0246230452223987 |
GO:0002009 | morphogenesis of an epithelium | 0.0298689584953271 |
GO:0007275 | multicellular organismal development | 0.0299029695567251 |
GO:0046914 | transition metal ion binding | 0.0336744915261688 |
GO:0035239 | tube morphogenesis | 0.0341194293784279 |
GO:0040008 | regulation of growth | 0.0341194293784279 |
GO:0007166 | cell surface receptor linked signal transduction | 0.0378219578990228 |
GO:0008284 | positive regulation of cell proliferation | 0.0395196813844614 |
GO:0016563 | transcription activator activity | 0.0395196813844614 |
GO:0007420 | brain development | 0.0403588074381917 |
GO:0007283 | spermatogenesis | 0.0417053039818248 |
GO:0048232 | male gamete generation | 0.0417053039818248 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.0417053039818248 |
GO:0032502 | developmental process | 0.0453064908291446 |
GO:0043009 | chordate embryonic development | 0.0457045477608513 |
GO:0009792 | embryonic development ending in birth or egg hatching | 0.0458064619401872 |
GO:0007417 | central nervous system development | 0.046709802065086 |
GO:0045893 | positive regulation of transcription, DNA-dependent | 0.0471956256633701 |
GO:0007276 | gamete generation | 0.0494386906563075 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
multi-cellular organism | 5.76e-08 | 333 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.34944 |
MA0004.1 | 0.6888 |
MA0006.1 | 0.497533 |
MA0007.1 | 0.672186 |
MA0009.1 | 1.15569 |
MA0014.1 | 0.581929 |
MA0017.1 | 0.528196 |
MA0019.1 | 0.964875 |
MA0024.1 | 1.11019 |
MA0025.1 | 1.39562 |
MA0027.1 | 2.81824 |
MA0028.1 | 0.509589 |
MA0029.1 | 1.08753 |
MA0030.1 | 1.09438 |
MA0031.1 | 1.05719 |
MA0038.1 | 0.846479 |
MA0040.1 | 1.16866 |
MA0041.1 | 0.604221 |
MA0042.1 | 0.589368 |
MA0043.1 | 1.25564 |
MA0046.1 | 1.1929 |
MA0048.1 | 0.266382 |
MA0050.1 | 1.73541 |
MA0051.1 | 0.856094 |
MA0052.1 | 1.17701 |
MA0055.1 | 0.125758 |
MA0056.1 | 0 |
MA0057.1 | 2.80216 |
MA0058.1 | 1.4226 |
MA0059.1 | 0.59559 |
MA0060.1 | 0.403071 |
MA0061.1 | 0.438628 |
MA0063.1 | 0 |
MA0066.1 | 1.94802 |
MA0067.1 | 1.50873 |
MA0068.1 | 0.256913 |
MA0069.1 | 1.17737 |
MA0070.1 | 1.16732 |
MA0071.1 | 0.73062 |
MA0072.1 | 1.15853 |
MA0073.1 | 8.63716 |
MA0074.1 | 0.795862 |
MA0076.1 | 0.550092 |
MA0077.1 | 1.13603 |
MA0078.1 | 0.891476 |
MA0081.1 | 0.621611 |
MA0083.1 | 1.25482 |
MA0084.1 | 1.84013 |
MA0087.1 | 1.21037 |
MA0088.1 | 1.1032 |
MA0089.1 | 0 |
MA0090.1 | 0.650768 |
MA0091.1 | 0.703314 |
MA0092.1 | 0.651119 |
MA0093.1 | 1.29026 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.783305 |
MA0101.1 | 0.605676 |
MA0103.1 | 0.540576 |
MA0105.1 | 0.841866 |
MA0106.1 | 0.899777 |
MA0107.1 | 0.533522 |
MA0108.2 | 0.989014 |
MA0109.1 | 0 |
MA0111.1 | 0.666525 |
MA0113.1 | 0.869608 |
MA0114.1 | 0.43587 |
MA0115.1 | 1.25852 |
MA0116.1 | 0.497293 |
MA0117.1 | 1.22527 |
MA0119.1 | 0.606338 |
MA0122.1 | 1.24573 |
MA0124.1 | 1.45461 |
MA0125.1 | 1.37907 |
MA0130.1 | 0 |
MA0131.1 | 0.960068 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.29308 |
MA0136.1 | 0.817395 |
MA0139.1 | 0.365453 |
MA0140.1 | 0.78318 |
MA0141.1 | 0.563066 |
MA0142.1 | 1.04199 |
MA0143.1 | 0.887119 |
MA0144.1 | 0.439506 |
MA0145.1 | 0.21199 |
MA0146.1 | 0.313734 |
MA0147.1 | 0.453952 |
MA0148.1 | 0.706718 |
MA0149.1 | 0.611881 |
MA0062.2 | 0.319836 |
MA0035.2 | 0.788288 |
MA0039.2 | 0.45096 |
MA0138.2 | 0.951653 |
MA0002.2 | 0.368961 |
MA0137.2 | 0.559766 |
MA0104.2 | 0.386166 |
MA0047.2 | 0.845655 |
MA0112.2 | 0.211985 |
MA0065.2 | 0.212467 |
MA0150.1 | 0.67206 |
MA0151.1 | 0 |
MA0152.1 | 0.84577 |
MA0153.1 | 1.31015 |
MA0154.1 | 0.728853 |
MA0155.1 | 1.21457 |
MA0156.1 | 0.549102 |
MA0157.1 | 2.30294 |
MA0158.1 | 0 |
MA0159.1 | 0.465802 |
MA0160.1 | 0.71003 |
MA0161.1 | 0 |
MA0162.1 | 0.346529 |
MA0163.1 | 3.61171 |
MA0164.1 | 0.817786 |
MA0080.2 | 0.534538 |
MA0018.2 | 0.828253 |
MA0099.2 | 0.944966 |
MA0079.2 | 9.08066 |
MA0102.2 | 1.8929 |
MA0258.1 | 0.419871 |
MA0259.1 | 0.441366 |
MA0442.1 | 0 |