UBERON:0001003: Difference between revisions
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|id=UBERON:0001003 | |id=UBERON:0001003 | ||
|is_a=UBERON:0007376;;UBERON: | |is_a=UBERON:0007376 ;;UBERON:3000961 | ||
|is_obsolete= | |is_obsolete= | ||
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|namespace= | |namespace= | ||
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|part_of=UBERON:0002097 | |part_of=UBERON:0002097 | ||
|preceded_by= | |preceded_by= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string;;UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string;;UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string;;UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string;;UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string | ||
Revision as of 10:58, 12 September 2014
| Name: | epidermis | ||
|---|---|---|---|
| Definition: | "The outer layer of the skin[WP]. cellular, multilayered epithelium derived from the ectoderm[ZFA]." [ISBN10:0073040584, Wikipedia:Epidermis_(skin)] | ||
| Xrefs: |
| ||
| Synonyms: |
"adult epidermis" EXACT [] "skin" BROAD [] "vertebrate epidermis" EXACT [] | ||
| Comments: | Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes). | ||
| Alt_id: | UBERON:FBbt_00004993-FBbt_00005401-FMA_70596-MA_0000153-MIAA_0000154-WBbt_0005733-XAO_0000028-ZFA_0000105 | ||
| Subset: |
uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0007376(outer epithelium),UBERON:3000961(external integument structure) |
|---|---|
| develops_from: | UBERON:0007383(enveloping layer of ectoderm) |
| part_of: | UBERON:0002097(skin of body) |
Children
| is a: | FF:0011174 (Skin - armpit hair follicle),FF:0011178 (Skin - torso),FF:0011459 (tongue epidermis (vallate papillae)- donor1) |
|---|---|
| derives from: | FF:0100849 (melanoma cell line sample) |
| develops from: | UBERON:0005086 (hair follicle placode) |
| part of: | CL:0000312 (keratinocyte),UBERON:0001705 (nail),UBERON:0001820 (sweat gland),UBERON:0001821 (sebaceous gland),UBERON:0002025 (stratum basale of epidermis),UBERON:0002073 (hair follicle),UBERON:0004882 (eponychium),UBERON:0007771 (epidermis gland),UBERON:0009564 (distal limb integumentary appendage),CL:1000428 (stem cell of epidermis) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10065-101I2 (skin, fetal, donor1)
- 10074-102A2 (skin, adult, donor1)
- 10273-104E3
- 10283-104F4
- 10286-104F7 (Skin - palm, donor1)
- 10287-104F8
- 10288-104F9 (tongue epidermis (fungiform papillae), donor1)
- 10289-104G1
- 10301-104H4 (Fingernail (including nail plate, eponychium and hyponychium), donor2)
- 10311-104I5
... further results Mouse (Mus musculus)
- 10065-101I2 (skin, fetal, donor1)
- 10074-102A2 (skin, adult, donor1)
- 10273-104E3
- 10283-104F4
- 10286-104F7 (Skin - palm, donor1)
- 10287-104F8
- 10288-104F9 (tongue epidermis (fungiform papillae), donor1)
- 10289-104G1
- 10301-104H4 (Fingernail (including nail plate, eponychium and hyponychium), donor2)
- 10311-104I5
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001003 (epidermis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.4e-86 | FFCP PHASE1:Mm9::chr11:94981134..94981147,+#_d815a566a39f91845066641869350398 | p2@Dlx3 |
| 1.4e-86 | FFCP PHASE2:Mm9::chr15:101593988..101593997,-#_d815a566a39f91845066641869350398 | p1@Krt74 |
| 1.4e-86 | FFCP PHASE1:Mm9::chr11:99227413..99227429,-#_d815a566a39f91845066641869350398 | p@chr11:99227413..99227429, - |
| 1.4e-86 | FFCP PHASE1:Mm9::chr15:101593988..101593997,-#_d815a566a39f91845066641869350398 | p1@Krt74 |
| 1.4e-86 | FFCP PHASE2:Mm9::chr4:138313406..138313411,-#_d815a566a39f91845066641869350398 | p2@Pla2g2f |
| 1.4e-86 | FFCP PHASE1:Mm9::chr4:113836042..113836053,+#_d815a566a39f91845066641869350398 | p2@Skint11 |
| 1.4e-86 | FFCP PHASE1:Mm9::chr4:138313406..138313411,-#_d815a566a39f91845066641869350398 | p2@Pla2g2f |
| 1.4e-86 | FFCP PHASE1:Mm9::chr5:137057540..137057550,-#_d815a566a39f91845066641869350398 | p@chr5:137057540..137057550, - |
| 1.4e-86 | FFCP PHASE2:Mm9::chr11:94981134..94981147,+#_d815a566a39f91845066641869350398 | p2@Dlx3 |
| 1.4e-86 | FFCP PHASE1:Mm9::chr4:113836063..113836075,+#_d815a566a39f91845066641869350398 | p1@Skint11 |
| 1.4e-86 | FFCP PHASE2:Mm9::chr4:113836042..113836053,+#_d815a566a39f91845066641869350398 | p2@Skint11 |
| 1.4e-86 | FFCP PHASE1:Mm9::chr1:191609138..191609151,+#_d815a566a39f91845066641869350398 | p@chr1:191609138..191609151, + |
| 1.4e-86 | FFCP PHASE2:Mm9::chr11:99227413..99227429,-#_d815a566a39f91845066641869350398 | p@chr11:99227413..99227429, - |
| 1.4e-86 | FFCP PHASE1:Mm9::chr13:113381448..113381495,-#_d815a566a39f91845066641869350398 | p@chr13:113381448..113381495, - |
| 1.4e-86 | FFCP PHASE2:Mm9::chr4:113836063..113836075,+#_d815a566a39f91845066641869350398 | p1@Skint11 |
| 1.4e-86 | FFCP PHASE2:Mm9::chr5:137057540..137057550,-#_d815a566a39f91845066641869350398 | p@chr5:137057540..137057550, - |
| 1.4e-86 | FFCP PHASE2:Mm9::chr13:113381448..113381495,-#_d815a566a39f91845066641869350398 | p@chr13:113381448..113381495, - |
| 1.4e-86 | FFCP PHASE2:Mm9::chr1:191609138..191609151,+#_d815a566a39f91845066641869350398 | p@chr1:191609138..191609151, + |
| 1.4e-86 | FFCP PHASE1:Mm9::chr11:36246521..36246530,-#_d815a566a39f91845066641869350398 | p@chr11:36246521..36246530, - |
| 1.4e-86 | FFCP PHASE2:Mm9::chr11:36246521..36246530,-#_d815a566a39f91845066641869350398 | p@chr11:36246521..36246530, - |
| 1.07e-72 | FFCP PHASE1:Mm9::chr5:137057441..137057450,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr5:137057441..137057450, - |
| 1.07e-72 | FFCP PHASE2:Mm9::chr11:99207849..99207853,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr11:99207849..99207853, - |
| 1.07e-72 | FFCP PHASE2:Mm9::chr5:137057441..137057450,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr5:137057441..137057450, - |
| 1.07e-72 | FFCP PHASE2:Mm9::chr7:97432305..97432311,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr7:97432305..97432311, + |
| 1.07e-72 | FFCP PHASE1:Mm9::chr5:137057490..137057506,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr5:137057490..137057506, - |
| 1.07e-72 | FFCP PHASE1:Mm9::chr1:133938531..133938534,-#_35c72a50cca2f8fa26f37b55e9e70114 | p6@Mfsd4 |
| 1.07e-72 | FFCP PHASE2:Mm9::chr7:127260268..127260277,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr7:127260268..127260277, + |
| 1.07e-72 | FFCP PHASE2:Mm9::chr5:137057490..137057506,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr5:137057490..137057506, - |
| 1.07e-72 | FFCP PHASE2:Mm9::chr1:133938531..133938534,-#_35c72a50cca2f8fa26f37b55e9e70114 | p6@Mfsd4 |
| 1.07e-72 | FFCP PHASE1:Mm9::chr1:46949894..46949911,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr1:46949894..46949911, - |
| 1.07e-72 | FFCP PHASE2:Mm9::chr15:83953604..83953633,-#_35c72a50cca2f8fa26f37b55e9e70114 | p1@Pnpla5 |
| 1.07e-72 | FFCP PHASE1:Mm9::chr11:99207849..99207853,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr11:99207849..99207853, - |
| 1.07e-72 | FFCP PHASE1:Mm9::chr3:90343597..90343613,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr3:90343597..90343613, + |
| 1.07e-72 | FFCP PHASE1:Mm9::chr7:97432305..97432311,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr7:97432305..97432311, + |
| 1.07e-72 | FFCP PHASE1:Mm9::chr7:127260268..127260277,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr7:127260268..127260277, + |
| 1.07e-72 | FFCP PHASE2:Mm9::chr3:90343597..90343613,+#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr3:90343597..90343613, + |
| 1.07e-72 | FFCP PHASE1:Mm9::chr15:83953604..83953633,-#_35c72a50cca2f8fa26f37b55e9e70114 | p1@Pnpla5 |
| 1.07e-72 | FFCP PHASE2:Mm9::chr1:46949894..46949911,-#_35c72a50cca2f8fa26f37b55e9e70114 | p@chr1:46949894..46949911, - |
| 1.5e-72 | FFCP PHASE1:Mm9::chr6:97778311..97778326,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr6:97778311..97778326, + |
| 1.5e-72 | FFCP PHASE2:Mm9::chr10:43724117..43724131,-#_048f4f3e503aa29828d3ad94c96cef09 | p@chr10:43724117..43724131, - |
| 1.5e-72 | FFCP PHASE2:Mm9::chr3:138004932..138004945,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr3:138004932..138004945, + |
| 1.5e-72 | FFCP PHASE2:Mm9::chr10:66991117..66991146,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr10:66991117..66991146, + |
| 1.5e-72 | FFCP PHASE1:Mm9::chr13:112045218..112045226,+#_048f4f3e503aa29828d3ad94c96cef09 | p1@Actbl2 |
| 1.5e-72 | FFCP PHASE2:Mm9::chr13:112045218..112045226,+#_048f4f3e503aa29828d3ad94c96cef09 | p1@Actbl2 |
| 1.5e-72 | FFCP PHASE1:Mm9::chr1:37973257..37973271,-#_048f4f3e503aa29828d3ad94c96cef09 | p2@Lyg2 |
| 1.5e-72 | FFCP PHASE1:Mm9::chr15:25672069..25672077,+#_048f4f3e503aa29828d3ad94c96cef09 | p25@Myo10 |
| 1.5e-72 | FFCP PHASE2:Mm9::chr6:97778311..97778326,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr6:97778311..97778326, + |
| 1.5e-72 | FFCP PHASE2:Mm9::chr6:134595955..134595965,-#_048f4f3e503aa29828d3ad94c96cef09 | p@chr6:134595955..134595965, - |
| 1.5e-72 | FFCP PHASE1:Mm9::chr10:43724117..43724131,-#_048f4f3e503aa29828d3ad94c96cef09 | p@chr10:43724117..43724131, - |
| 1.5e-72 | FFCP PHASE2:Mm9::chr1:37973257..37973271,-#_048f4f3e503aa29828d3ad94c96cef09 | p2@Lyg2 |
| 1.5e-72 | FFCP PHASE1:Mm9::chr1:37973330..37973344,-#_048f4f3e503aa29828d3ad94c96cef09 | p1@Lyg2 |
| 1.5e-72 | FFCP PHASE2:Mm9::chr15:25672069..25672077,+#_048f4f3e503aa29828d3ad94c96cef09 | p25@Myo10 |
| 1.5e-72 | FFCP PHASE1:Mm9::chr10:66991117..66991146,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr10:66991117..66991146, + |
| 1.5e-72 | FFCP PHASE2:Mm9::chr1:37973330..37973344,-#_048f4f3e503aa29828d3ad94c96cef09 | p1@Lyg2 |
| 1.5e-72 | FFCP PHASE1:Mm9::chr6:134595955..134595965,-#_048f4f3e503aa29828d3ad94c96cef09 | p@chr6:134595955..134595965, - |
| 1.5e-72 | FFCP PHASE1:Mm9::chr3:138004932..138004945,+#_048f4f3e503aa29828d3ad94c96cef09 | p@chr3:138004932..138004945, + |
| 2.1e-72 | FFCP PHASE2:Mm9::chr1:89485356..89485361,+#_23d0dca5fc094d401a4162eead8f3fba | p@chr1:89485356..89485361, + |
| 2.1e-72 | FFCP PHASE1:Mm9::chr1:89485356..89485361,+#_23d0dca5fc094d401a4162eead8f3fba | p@chr1:89485356..89485361, + |
| 2.1e-72 | FFCP PHASE2:Mm9::chr7:117436977..117436981,-#_23d0dca5fc094d401a4162eead8f3fba | p@chr7:117436977..117436981, - |
| 2.1e-72 | FFCP PHASE2:Mm9::chr4:82496625..82496637,-#_23d0dca5fc094d401a4162eead8f3fba | p6@Zdhhc21 |
| 2.1e-72 | FFCP PHASE1:Mm9::chr4:111707315..111707319,+#_23d0dca5fc094d401a4162eead8f3fba | p@chr4:111707315..111707319, + |
| 2.1e-72 | FFCP PHASE1:Mm9::chr7:117436977..117436981,-#_23d0dca5fc094d401a4162eead8f3fba | p@chr7:117436977..117436981, - |
| 2.1e-72 | FFCP PHASE1:Mm9::chr4:82496625..82496637,-#_23d0dca5fc094d401a4162eead8f3fba | p6@Zdhhc21 |
| 2.1e-72 | FFCP PHASE2:Mm9::chr4:111707315..111707319,+#_23d0dca5fc094d401a4162eead8f3fba | p@chr4:111707315..111707319, + |
| 4.13e-72 | FFCP PHASE2:Mm9::chr4:113672105..113672116,-#_75881265724b5394dfcedbcefb0c18c0 | p1@Skint5 |
| 4.13e-72 | FFCP PHASE1:Mm9::chr4:113672105..113672116,-#_75881265724b5394dfcedbcefb0c18c0 | p1@Skint5 |
| 1.65e-69 | FFCP PHASE2:Mm9::chr3:93248889..93248897,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93248889..93248897, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr3:93247552..93247564,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93247552..93247564, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr2:129949046..129949050,+#_47627590e07b81024b47854cbf08cad9 | p2@Tgm6 |
| 1.65e-69 | FFCP PHASE1:Mm9::chr14:57868950..57868959,+#_47627590e07b81024b47854cbf08cad9 | p@chr14:57868950..57868959, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr11:95086849..95086855,-#_47627590e07b81024b47854cbf08cad9 | p3@ENSMUST00000150818 |
| 1.65e-69 | FFCP PHASE2:Mm9::chr4:57351817..57351823,-#_47627590e07b81024b47854cbf08cad9 | p@chr4:57351817..57351823, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr3:93250018..93250027,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93250018..93250027, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr9:43876286..43876293,+#_47627590e07b81024b47854cbf08cad9 | p@chr9:43876286..43876293, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr18:20631745..20631746,+#_47627590e07b81024b47854cbf08cad9 | p@chr18:20631745..20631746, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr3:93249140..93249149,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93249140..93249149, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr3:59629633..59629644,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:59629633..59629644, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr4:135527809..135527823,-#_47627590e07b81024b47854cbf08cad9 | p4@Lypla2 |
| 1.65e-69 | FFCP PHASE1:Mm9::chr19:59989963..59989986,-#_47627590e07b81024b47854cbf08cad9 | p@chr19:59989963..59989986, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr19:25196775..25196781,+#_47627590e07b81024b47854cbf08cad9 | p@chr19:25196775..25196781, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr11:99957587..99957593,-#_47627590e07b81024b47854cbf08cad9 | p2@Krt35 |
| 1.65e-69 | FFCP PHASE1:Mm9::chr17:14011908..14011919,+#_47627590e07b81024b47854cbf08cad9 | p13@Mllt4 |
| 1.65e-69 | FFCP PHASE2:Mm9::chr4:82496602..82496610,-#_47627590e07b81024b47854cbf08cad9 | p8@Zdhhc21 |
| 1.65e-69 | FFCP PHASE2:Mm9::chr6:142831327..142831375,+#_47627590e07b81024b47854cbf08cad9 | p@chr6:142831327..142831375, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr9:43876286..43876293,+#_47627590e07b81024b47854cbf08cad9 | p@chr9:43876286..43876293, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr3:93249391..93249400,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93249391..93249400, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr9:67169769..67169780,-#_47627590e07b81024b47854cbf08cad9 | p@chr9:67169769..67169780, - |
| 1.65e-69 | FFCP PHASE2:Mm9::chr3:93248462..93248471,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93248462..93248471, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chrX:166374681..166374688,+#_47627590e07b81024b47854cbf08cad9 | p@chrX:166374681..166374688, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr16:56831943..56831948,-#_47627590e07b81024b47854cbf08cad9 | p14@Tmem45a |
| 1.65e-69 | FFCP PHASE2:Mm9::chr5:113617681..113617724,-#_47627590e07b81024b47854cbf08cad9 | p@chr5:113617681..113617724, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr3:93247570..93247579,+#_47627590e07b81024b47854cbf08cad9 | p@chr3:93247570..93247579, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr11:99913595..99913606,+#_47627590e07b81024b47854cbf08cad9 | p1@ENSMUST00000136820, p1@uc007lke.1 |
| 1.65e-69 | FFCP PHASE1:Mm9::chr18:25099958..25099967,+#_47627590e07b81024b47854cbf08cad9 | p@chr18:25099958..25099967, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr6:97778294..97778306,+#_47627590e07b81024b47854cbf08cad9 | p@chr6:97778294..97778306, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr11:99957587..99957593,-#_47627590e07b81024b47854cbf08cad9 | p2@Krt35 |
| 1.65e-69 | FFCP PHASE1:Mm9::chr6:97778346..97778356,+#_47627590e07b81024b47854cbf08cad9 | p@chr6:97778346..97778356, + |
| 1.65e-69 | FFCP PHASE1:Mm9::chr5:113617681..113617724,-#_47627590e07b81024b47854cbf08cad9 | p@chr5:113617681..113617724, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr18:20631745..20631746,+#_47627590e07b81024b47854cbf08cad9 | p@chr18:20631745..20631746, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr1:192537956..192537958,+#_47627590e07b81024b47854cbf08cad9 | p@chr1:192537956..192537958, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
