Novel motif:121

name:	motif121_TGCAWTGTA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0046032	ADP catabolic process	1.376928e-16
GO:0046709	IDP catabolic process	1.376928e-16
GO:0032501	multicellular organismal process	1.020848e-15
GO:0009181	purine ribonucleoside diphosphate catabolic process	6.011790e-14
GO:0051606	detection of stimulus	2.026081e-13
GO:0016337	cell-cell adhesion	6.350196e-13
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	8.408898e-13
GO:0048513	organ development	8.127035e-12
GO:0007155	cell adhesion	1.052215e-11
GO:0051179	localization	1.182261e-11
GO:0009191	ribonucleoside diphosphate catabolic process	1.945206e-11
GO:0065008	regulation of biological quality	6.366251e-11
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	7.024000e-11
GO:0051602	response to electrical stimulus	7.098922e-11
GO:0002376	immune system process	9.102573e-11
GO:0045666	positive regulation of neuron differentiation	1.508881e-10
GO:0050896	response to stimulus	1.794263e-10
GO:0006928	cellular component movement	1.935440e-10
GO:0009582	detection of abiotic stimulus	1.960641e-10
GO:0009611	response to wounding	2.311955e-10
GO:0048856	anatomical structure development	2.580254e-10
GO:0010038	response to metal ion	4.915576e-10
GO:0009888	tissue development	4.918556e-10
GO:0006953	acute-phase response	5.424383e-10
GO:0048731	system development	5.909890e-10
GO:0009581	detection of external stimulus	7.255502e-10
GO:0030178	negative regulation of Wnt receptor signaling pathway	1.128391e-9
GO:0050900	leukocyte migration	1.280175e-9
GO:0042060	wound healing	1.423870e-9
GO:0016477	cell migration	1.496131e-9
GO:0023057	negative regulation of signaling	1.506501e-9
GO:0010648	negative regulation of cell communication	1.588337e-9
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.803122e-9
GO:0007611	learning or memory	1.857690e-9
GO:0032502	developmental process	2.259217e-9
GO:0045428	regulation of nitric oxide biosynthetic process	2.510965e-9
GO:0009653	anatomical structure morphogenesis	3.138939e-9
GO:0009607	response to biotic stimulus	3.139013e-9
GO:0009628	response to abiotic stimulus	3.793515e-9
GO:0006811	ion transport	4.215182e-9
GO:0009612	response to mechanical stimulus	4.246403e-9
GO:0007275	multicellular organismal development	4.298619e-9
GO:0050890	cognition	4.300189e-9
GO:0003008	system process	5.563296e-9
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	6.848174e-9
GO:0002526	acute inflammatory response	7.594232e-9
GO:0009617	response to bacterium	9.878527e-9
GO:0008228	opsonization	1.036017e-8
GO:0048518	positive regulation of biological process	1.447346e-8
GO:0010035	response to inorganic substance	1.484575e-8
GO:0006950	response to stress	2.058224e-8
GO:0006942	regulation of striated muscle contraction	2.232276e-8
GO:0007599	hemostasis	2.801115e-8
GO:0048870	cell motility	3.309873e-8
GO:0051707	response to other organism	3.547699e-8
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.586543e-8
GO:0007596	blood coagulation	3.814598e-8
GO:0007602	phototransduction	3.894000e-8
GO:0007610	behavior	4.294511e-8
GO:0050906	detection of stimulus involved in sensory perception	4.334283e-8
GO:0046031	ADP metabolic process	5.119355e-8
GO:0048869	cellular developmental process	5.279970e-8
GO:0050793	regulation of developmental process	6.171428e-8
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	8.574516e-8
GO:0090076	relaxation of skeletal muscle	8.574516e-8
GO:0010574	regulation of vascular endothelial growth factor production	9.334245e-8
GO:0040011	locomotion	9.389453e-8
GO:0032989	cellular component morphogenesis	9.651463e-8
GO:0050974	detection of mechanical stimulus involved in sensory perception	9.723852e-8
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.241498e-7
GO:0006875	cellular metal ion homeostasis	1.305317e-7
GO:0009235	cobalamin metabolic process	1.346598e-7
GO:0008360	regulation of cell shape	1.400168e-7
GO:0044057	regulation of system process	1.680544e-7
GO:0030154	cell differentiation	1.879196e-7
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	2.058585e-7
GO:0010042	response to manganese ion	2.501465e-7
GO:0050982	detection of mechanical stimulus	2.560402e-7
GO:0007517	muscle organ development	2.794714e-7
GO:0048522	positive regulation of cellular process	2.868302e-7
GO:0009605	response to external stimulus	2.874904e-7
GO:0001558	regulation of cell growth	3.093894e-7
GO:0055065	metal ion homeostasis	3.144646e-7
GO:0009968	negative regulation of signal transduction	3.479884e-7
GO:0042221	response to chemical stimulus	3.536642e-7
GO:0050878	regulation of body fluid levels	3.679519e-7
GO:0065007	biological regulation	3.752863e-7
GO:0071287	cellular response to manganese ion	3.985383e-7
GO:0048583	regulation of response to stimulus	4.115709e-7
GO:0061024	membrane organization	4.307693e-7
GO:0030003	cellular cation homeostasis	4.325327e-7
GO:0048514	blood vessel morphogenesis	4.935352e-7
GO:0031946	regulation of glucocorticoid biosynthetic process	5.034835e-7
GO:0006810	transport	5.281725e-7
GO:0016044	cellular membrane organization	5.611655e-7
GO:0030301	cholesterol transport	5.774655e-7
GO:0015918	sterol transport	5.996300e-7
GO:0030111	regulation of Wnt receptor signaling pathway	6.022993e-7
GO:0014049	positive regulation of glutamate secretion	6.093527e-7
GO:0042418	epinephrine biosynthetic process	6.128915e-7
GO:0006585	dopamine biosynthetic process from tyrosine	6.128915e-7
GO:0072358	cardiovascular system development	6.968432e-7
GO:0048878	chemical homeostasis	7.198720e-7
GO:0052314	phytoalexin metabolic process	7.590143e-7
GO:0042127	regulation of cell proliferation	7.996912e-7
GO:0055082	cellular chemical homeostasis	8.332564e-7
GO:0051239	regulation of multicellular organismal process	8.407593e-7
GO:0051234	establishment of localization	8.675057e-7
GO:0015889	cobalamin transport	9.430576e-7
GO:0051047	positive regulation of secretion	1.047965e-6
GO:0014048	regulation of glutamate secretion	1.054826e-6
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.093499e-6
GO:0009185	ribonucleoside diphosphate metabolic process	1.113419e-6
GO:0001780	neutrophil homeostasis	1.113419e-6
GO:0072001	renal system development	1.120409e-6
GO:0051704	multi-organism process	1.164798e-6
GO:0048468	cell development	1.268992e-6
GO:0006542	glutamine biosynthetic process	1.483060e-6
GO:0030431	sleep	1.499472e-6
GO:0007613	memory	1.537163e-6
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.688844e-6
GO:0002090	regulation of receptor internalization	1.706130e-6
GO:0072511	divalent inorganic cation transport	1.716706e-6
GO:0010646	regulation of cell communication	1.748801e-6
GO:0048646	anatomical structure formation involved in morphogenesis	1.868410e-6
GO:0015669	gas transport	2.001446e-6
GO:0042743	hydrogen peroxide metabolic process	2.025302e-6
GO:0042744	hydrogen peroxide catabolic process	2.053910e-6
GO:0001655	urogenital system development	2.242352e-6
GO:0090336	positive regulation of brown fat cell differentiation	2.267560e-6
GO:0090362	positive regulation of platelet-derived growth factor production	2.267560e-6
GO:0090271	positive regulation of fibroblast growth factor production	2.267560e-6
GO:0035845	photoreceptor cell outer segment organization	2.336161e-6
GO:0090287	regulation of cellular response to growth factor stimulus	2.549102e-6
GO:0001932	regulation of protein phosphorylation	2.558713e-6
GO:2000021	regulation of ion homeostasis	2.640068e-6
GO:0009583	detection of light stimulus	2.682536e-6
GO:0042325	regulation of phosphorylation	2.948256e-6
GO:0016192	vesicle-mediated transport	3.080578e-6
GO:0014823	response to activity	3.091817e-6
GO:0007210	serotonin receptor signaling pathway	3.106398e-6
GO:0055080	cation homeostasis	3.112469e-6
GO:0072503	cellular divalent inorganic cation homeostasis	3.162816e-6
GO:0006874	cellular calcium ion homeostasis	3.210122e-6
GO:0006873	cellular ion homeostasis	3.372219e-6
GO:0042414	epinephrine metabolic process	3.487565e-6
GO:0000902	cell morphogenesis	3.664643e-6
GO:0040008	regulation of growth	3.676735e-6
GO:0032496	response to lipopolysaccharide	3.722306e-6
GO:0033076	isoquinoline alkaloid metabolic process	3.789196e-6
GO:0007158	neuron cell-cell adhesion	3.811938e-6
GO:0045162	clustering of voltage-gated sodium channels	3.865949e-6
GO:0002237	response to molecule of bacterial origin	3.905766e-6
GO:0006816	calcium ion transport	4.113487e-6
GO:0046689	response to mercury ion	4.205374e-6
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	4.264753e-6
GO:0032846	positive regulation of homeostatic process	4.355150e-6
GO:0043402	glucocorticoid mediated signaling pathway	4.498714e-6
GO:0015671	oxygen transport	4.609639e-6
GO:0035176	social behavior	4.724383e-6
GO:0006812	cation transport	4.790024e-6
GO:0019725	cellular homeostasis	4.807748e-6
GO:0045410	positive regulation of interleukin-6 biosynthetic process	4.979558e-6
GO:0055074	calcium ion homeostasis	4.981777e-6
GO:0019220	regulation of phosphate metabolic process	5.056794e-6
GO:0006959	humoral immune response	5.280841e-6
GO:0071840	cellular component organization or biogenesis	5.367376e-6
GO:0001822	kidney development	5.480958e-6
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	5.655816e-6
GO:0010575	positive regulation vascular endothelial growth factor production	5.778789e-6
GO:0007612	learning	5.784240e-6
GO:0003007	heart morphogenesis	5.863908e-6
GO:0019233	sensory perception of pain	6.059676e-6
GO:0048585	negative regulation of response to stimulus	6.068104e-6
GO:0030728	ovulation	6.298790e-6
GO:0030185	nitric oxide transport	6.702246e-6
GO:0050789	regulation of biological process	6.747129e-6
GO:0016043	cellular component organization	7.102767e-6
GO:0001659	temperature homeostasis	7.394679e-6
GO:0008038	neuron recognition	7.543710e-6
GO:0050801	ion homeostasis	7.656869e-6
GO:0006952	defense response	7.747852e-6
GO:0030001	metal ion transport	8.206717e-6
GO:0072507	divalent inorganic cation homeostasis	8.964363e-6
GO:0051967	negative regulation of synaptic transmission, glutamatergic	9.064486e-6
GO:0032770	positive regulation of monooxygenase activity	9.562818e-6
GO:0007166	cell surface receptor linked signaling pathway	9.683650e-6
GO:0032879	regulation of localization	9.721910e-6
GO:0019227	neuronal action potential propagation	9.970271e-6
GO:0045161	neuronal ion channel clustering	1.013713e-5
GO:0010822	positive regulation of mitochondrion organization	1.013713e-5
GO:0034614	cellular response to reactive oxygen species	1.043700e-5
GO:0006954	inflammatory response	1.067031e-5
GO:0010883	regulation of lipid storage	1.091683e-5
GO:0051142	positive regulation of NK T cell proliferation	1.151440e-5
GO:0002711	positive regulation of T cell mediated immunity	1.212255e-5
GO:0042214	terpene metabolic process	1.212879e-5
GO:0010350	cellular response to magnesium starvation	1.235643e-5
GO:0022603	regulation of anatomical structure morphogenesis	1.258594e-5
GO:0061061	muscle structure development	1.271805e-5
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	1.292513e-5
GO:0002092	positive regulation of receptor internalization	1.330009e-5
GO:0001568	blood vessel development	1.340221e-5
GO:0060537	muscle tissue development	1.360463e-5
GO:0006897	endocytosis	1.398778e-5
GO:0043380	regulation of memory T cell differentiation	1.467137e-5
GO:0031622	positive regulation of fever generation	1.491838e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.494629e-5
GO:0048169	regulation of long-term neuronal synaptic plasticity	1.533149e-5
GO:0031341	regulation of cell killing	1.537918e-5
GO:0023052	signaling	1.548817e-5
GO:0031943	regulation of glucocorticoid metabolic process	1.616433e-5
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.618904e-5
GO:0090270	regulation of fibroblast growth factor production	1.629528e-5
GO:0001944	vasculature development	1.762645e-5
GO:0002709	regulation of T cell mediated immunity	1.796917e-5
GO:0009966	regulation of signal transduction	1.822718e-5
GO:0071320	cellular response to cAMP	1.825323e-5
GO:0051966	regulation of synaptic transmission, glutamatergic	1.889700e-5
GO:0051716	cellular response to stimulus	1.990047e-5
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	2.010232e-5
GO:0042592	homeostatic process	2.066103e-5
GO:0071396	cellular response to lipid	2.066853e-5
GO:0030325	adrenal gland development	2.077824e-5
GO:0031645	negative regulation of neurological system process	2.099686e-5
GO:0002706	regulation of lymphocyte mediated immunity	2.107497e-5
GO:0048769	sarcomerogenesis	2.118394e-5
GO:0016339	calcium-dependent cell-cell adhesion	2.197817e-5
GO:0009593	detection of chemical stimulus	2.239837e-5
GO:0032844	regulation of homeostatic process	2.277671e-5
GO:0009408	response to heat	2.300355e-5
GO:0034374	low-density lipoprotein particle remodeling	2.353926e-5
GO:0048729	tissue morphogenesis	2.362729e-5
GO:0070838	divalent metal ion transport	2.473091e-5
GO:0014842	regulation of satellite cell proliferation	2.577702e-5
GO:0031652	positive regulation of heat generation	2.603571e-5
GO:0048519	negative regulation of biological process	2.658452e-5
GO:0048853	forebrain morphogenesis	2.663776e-5
GO:0007157	heterophilic cell-cell adhesion	2.667465e-5
GO:0050907	detection of chemical stimulus involved in sensory perception	2.736792e-5
GO:0007165	signal transduction	2.817037e-5
GO:0051209	release of sequestered calcium ion into cytosol	2.887759e-5
GO:0042632	cholesterol homeostasis	2.898543e-5
GO:0031394	positive regulation of prostaglandin biosynthetic process	2.956319e-5
GO:0006937	regulation of muscle contraction	3.093187e-5
GO:0070301	cellular response to hydrogen peroxide	3.140745e-5
GO:0006781	succinyl-CoA pathway	3.174160e-5
GO:0050671	positive regulation of lymphocyte proliferation	3.322062e-5
GO:0018149	peptide cross-linking	3.373190e-5
GO:0060538	skeletal muscle organ development	3.373720e-5
GO:0051969	regulation of transmission of nerve impulse	3.393745e-5
GO:0009132	nucleoside diphosphate metabolic process	3.411099e-5
GO:0045765	regulation of angiogenesis	3.428118e-5
GO:0032768	regulation of monooxygenase activity	3.455845e-5
GO:0055003	cardiac myofibril assembly	3.589140e-5
GO:0008285	negative regulation of cell proliferation	3.679205e-5
GO:0014889	muscle atrophy	3.731653e-5
GO:0051384	response to glucocorticoid stimulus	3.774840e-5
GO:0032621	interleukin-18 production	3.798903e-5
GO:0002252	immune effector process	3.851780e-5
GO:0006958	complement activation, classical pathway	3.853763e-5
GO:0043408	regulation of MAPKKK cascade	3.879737e-5
GO:0072376	protein activation cascade	3.942599e-5
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3.963502e-5
GO:0031644	regulation of neurological system process	3.982608e-5
GO:0003307	regulation of Wnt receptor signaling pathway involved in heart development	4.082867e-5
GO:0001775	cell activation	4.193265e-5
GO:0007156	homophilic cell adhesion	4.281283e-5
GO:0051282	regulation of sequestering of calcium ion	4.452878e-5
GO:0050870	positive regulation of T cell activation	4.454095e-5
GO:0051970	negative regulation of transmission of nerve impulse	4.475708e-5
GO:0009887	organ morphogenesis	4.825587e-5
GO:0045472	response to ether	4.855613e-5
GO:0034373	intermediate-density lipoprotein particle remodeling	5.012153e-5
GO:0034599	cellular response to oxidative stress	5.100787e-5
GO:0048643	positive regulation of skeletal muscle tissue development	5.319736e-5
GO:0032819	positive regulation of natural killer cell proliferation	5.437489e-5
GO:0032924	activin receptor signaling pathway	5.500368e-5
GO:0009306	protein secretion	5.532761e-5
GO:0051341	regulation of oxidoreductase activity	5.601264e-5
GO:0071248	cellular response to metal ion	5.714414e-5
GO:0051353	positive regulation of oxidoreductase activity	5.774298e-5
GO:0010942	positive regulation of cell death	5.873135e-5
GO:0032946	positive regulation of mononuclear cell proliferation	6.197098e-5
GO:0015722	canalicular bile acid transport	6.543789e-5
GO:0006824	cobalt ion transport	6.638525e-5
GO:0042178	xenobiotic catabolic process	6.833151e-5
GO:0014706	striated muscle tissue development	6.839805e-5
GO:0001525	angiogenesis	6.898280e-5
GO:0050810	regulation of steroid biosynthetic process	6.964776e-5
GO:0030240	skeletal muscle thin filament assembly	7.013682e-5
GO:0007154	cell communication	7.016739e-5
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	7.107581e-5
GO:0006111	regulation of gluconeogenesis	7.176830e-5
GO:0051251	positive regulation of lymphocyte activation	7.182046e-5
GO:0023051	regulation of signaling	7.327401e-5
GO:0070509	calcium ion import	7.409580e-5
GO:0030241	skeletal muscle myosin thick filament assembly	7.634583e-5
GO:0043409	negative regulation of MAPKKK cascade	7.668594e-5
GO:0090257	regulation of muscle system process	7.799592e-5
GO:0019216	regulation of lipid metabolic process	7.810598e-5
GO:0008037	cell recognition	7.823016e-5
GO:0070286	axonemal dynein complex assembly	7.984742e-5
GO:0071241	cellular response to inorganic substance	8.134227e-5
GO:0071286	cellular response to magnesium ion	8.138736e-5
GO:0006956	complement activation	8.152609e-5
GO:0015855	pyrimidine base transport	8.278279e-5
GO:0034638	phosphatidylcholine catabolic process	8.567910e-5
GO:0000904	cell morphogenesis involved in differentiation	8.734696e-5
GO:0046649	lymphocyte activation	9.000455e-5
GO:0035037	sperm entry	9.092330e-5
GO:0055013	cardiac muscle cell development	9.100255e-5
GO:0010743	regulation of macrophage derived foam cell differentiation	9.129641e-5
GO:0021509	roof plate formation	9.131483e-5
GO:0001781	neutrophil apoptosis	9.183675e-5
GO:0032817	regulation of natural killer cell proliferation	9.353299e-5
GO:0046903	secretion	9.409604e-5
GO:2000026	regulation of multicellular organismal development	9.485701e-5
GO:0034105	positive regulation of tissue remodeling	9.506433e-5
GO:0010886	positive regulation of cholesterol storage	9.582830e-5
GO:0006066	alcohol metabolic process	9.717668e-5
GO:0070164	negative regulation of adiponectin secretion	9.895329e-5
GO:0035505	positive regulation of myosin light chain kinase activity	9.895329e-5
GO:0060355	positive regulation of cell adhesion molecule production	9.895329e-5
GO:0051050	positive regulation of transport	9.904066e-5
GO:0051128	regulation of cellular component organization	9.913858e-5
GO:0042102	positive regulation of T cell proliferation	1.000575e-4
GO:0002262	myeloid cell homeostasis	1.013766e-4
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	1.022624e-4
GO:0003142	cardiogenic plate morphogenesis	1.022624e-4
GO:0015842	synaptic vesicle amine transport	1.022624e-4
GO:0051131	chaperone-mediated protein complex assembly	1.046709e-4
GO:0050794	regulation of cellular process	1.060818e-4
GO:0002769	natural killer cell inhibitory signaling pathway	1.086148e-4
GO:0045769	negative regulation of asymmetric cell division	1.086148e-4
GO:0051272	positive regulation of cellular component movement	1.121098e-4
GO:0051960	regulation of nervous system development	1.133061e-4
GO:0046885	regulation of hormone biosynthetic process	1.181191e-4
GO:0050776	regulation of immune response	1.203073e-4
GO:0033552	response to vitamin B3	1.208683e-4
GO:0007267	cell-cell signaling	1.237679e-4
GO:0051657	maintenance of organelle location	1.252909e-4
GO:0001816	cytokine production	1.277832e-4
GO:0032940	secretion by cell	1.288406e-4
GO:0034381	plasma lipoprotein particle clearance	1.294951e-4
GO:0046329	negative regulation of JNK cascade	1.307057e-4
GO:0040017	positive regulation of locomotion	1.376952e-4
GO:0010817	regulation of hormone levels	1.397751e-4
GO:0008284	positive regulation of cell proliferation	1.410841e-4
GO:0055088	lipid homeostasis	1.428148e-4
GO:0061031	endodermal digestive tract morphogenesis	1.447813e-4
GO:0070163	regulation of adiponectin secretion	1.460450e-4
GO:0009987	cellular process	1.490706e-4
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	1.503595e-4
GO:0090361	regulation of platelet-derived growth factor production	1.529906e-4
GO:0051561	elevation of mitochondrial calcium ion concentration	1.575852e-4
GO:0007600	sensory perception	1.598610e-4
GO:0030900	forebrain development	1.611599e-4
GO:0045893	positive regulation of transcription, DNA-dependent	1.627819e-4
GO:0043549	regulation of kinase activity	1.648480e-4
GO:0007631	feeding behavior	1.653495e-4
GO:0043407	negative regulation of MAP kinase activity	1.725843e-4
GO:0015825	L-serine transport	1.730806e-4
GO:0048854	brain morphogenesis	1.759725e-4
GO:0090149	membrane fission involved in mitochondrial fission	1.764960e-4
GO:0003374	dynamin polymerization involved in mitochondrial fission	1.764960e-4
GO:0051705	behavioral interaction between organisms	1.765434e-4
GO:0051093	negative regulation of developmental process	1.773985e-4
GO:0050867	positive regulation of cell activation	1.796040e-4
GO:0019371	cyclooxygenase pathway	1.817690e-4
GO:0050877	neurological system process	1.817757e-4
GO:0001947	heart looping	1.823372e-4
GO:0030518	steroid hormone receptor signaling pathway	1.831725e-4
GO:0070665	positive regulation of leukocyte proliferation	1.849152e-4
GO:0019835	cytolysis	1.856155e-4
GO:0051592	response to calcium ion	1.869355e-4
GO:0016140	O-glycoside metabolic process	1.870378e-4
GO:0045907	positive regulation of vasoconstriction	1.871656e-4
GO:0048634	regulation of muscle organ development	1.885966e-4
GO:0043933	macromolecular complex subunit organization	1.892637e-4
GO:0045597	positive regulation of cell differentiation	1.921835e-4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.981644e-4
GO:0048096	chromatin-mediated maintenance of transcription	1.995771e-4
GO:0007586	digestion	2.002096e-4
GO:0060438	trachea development	2.011099e-4
GO:0050805	negative regulation of synaptic transmission	2.027080e-4
GO:0090129	positive regulation of synapse maturation	2.052695e-4
GO:0050918	positive chemotaxis	2.061783e-4
GO:0010821	regulation of mitochondrion organization	2.092917e-4
GO:0009743	response to carbohydrate stimulus	2.145750e-4
GO:0050863	regulation of T cell activation	2.171550e-4
GO:0002455	humoral immune response mediated by circulating immunoglobulin	2.197471e-4
GO:0009266	response to temperature stimulus	2.203208e-4
GO:0043267	negative regulation of potassium ion transport	2.233768e-4
GO:0032874	positive regulation of stress-activated MAPK cascade	2.265469e-4
GO:0007076	mitotic chromosome condensation	2.319520e-4
GO:0045844	positive regulation of striated muscle tissue development	2.347574e-4
GO:0007204	elevation of cytosolic calcium ion concentration	2.420695e-4
GO:0007608	sensory perception of smell	2.440489e-4
GO:0010628	positive regulation of gene expression	2.465936e-4
GO:0048660	regulation of smooth muscle cell proliferation	2.497684e-4
GO:0033280	response to vitamin D	2.572775e-4
GO:0071901	negative regulation of protein serine/threonine kinase activity	2.661222e-4
GO:0001890	placenta development	2.661683e-4
GO:0042346	positive regulation of NF-kappaB import into nucleus	2.679409e-4
GO:0045408	regulation of interleukin-6 biosynthetic process	2.689136e-4
GO:0043525	positive regulation of neuron apoptosis	2.731197e-4
GO:0048245	eosinophil chemotaxis	2.732182e-4
GO:0045859	regulation of protein kinase activity	2.755252e-4
GO:0002251	organ or tissue specific immune response	2.819122e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	2.858872e-4
GO:0050803	regulation of synapse structure and activity	2.889419e-4
GO:0042953	lipoprotein transport	2.901322e-4
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	2.931585e-4
GO:0007519	skeletal muscle tissue development	3.066864e-4
GO:0071705	nitrogen compound transport	3.099948e-4
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	3.108770e-4
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	3.109558e-4
GO:0007368	determination of left/right symmetry	3.111609e-4
GO:0071637	regulation of monocyte chemotactic protein-1 production	3.126197e-4
GO:0002696	positive regulation of leukocyte activation	3.131803e-4
GO:0009566	fertilization	3.173052e-4
GO:0045664	regulation of neuron differentiation	3.248237e-4
GO:0070887	cellular response to chemical stimulus	3.264101e-4
GO:0032835	glomerulus development	3.269633e-4
GO:0014059	regulation of dopamine secretion	3.288552e-4
GO:0090128	regulation of synapse maturation	3.356680e-4
GO:0031536	positive regulation of exit from mitosis	3.356680e-4
GO:0007160	cell-matrix adhesion	3.370236e-4
GO:0070588	calcium ion transmembrane transport	3.537825e-4
GO:0050718	positive regulation of interleukin-1 beta secretion	3.553836e-4
GO:0032872	regulation of stress-activated MAPK cascade	3.558262e-4
GO:0051173	positive regulation of nitrogen compound metabolic process	3.587891e-4
GO:0030097	hemopoiesis	3.670433e-4
GO:0043113	receptor clustering	3.748883e-4
GO:0046486	glycerolipid metabolic process	3.752900e-4
GO:0046549	retinal cone cell development	3.777898e-4
GO:0097091	synaptic vesicle clustering	3.803012e-4
GO:0001706	endoderm formation	3.818792e-4
GO:0032026	response to magnesium ion	3.831690e-4
GO:0046890	regulation of lipid biosynthetic process	3.879105e-4
GO:0051258	protein polymerization	3.955566e-4
GO:0006935	chemotaxis	3.955785e-4
GO:0014866	skeletal myofibril assembly	3.962565e-4
GO:0022607	cellular component assembly	3.969061e-4
GO:0007413	axonal fasciculation	4.014983e-4
GO:0009314	response to radiation	4.043155e-4
GO:0015851	nucleobase transport	4.070583e-4
GO:0051480	cytosolic calcium ion homeostasis	4.119569e-4
GO:0001831	trophectodermal cellular morphogenesis	4.149265e-4
GO:0034369	plasma lipoprotein particle remodeling	4.151952e-4
GO:0034372	very-low-density lipoprotein particle remodeling	4.198393e-4
GO:0010565	regulation of cellular ketone metabolic process	4.205538e-4
GO:0044060	regulation of endocrine process	4.268521e-4
GO:0001696	gastric acid secretion	4.271401e-4
GO:0042129	regulation of T cell proliferation	4.278516e-4
GO:0008544	epidermis development	4.473779e-4
GO:0097114	N-methyl-D-aspartate receptor clustering	4.503889e-4
GO:0097112	gamma-aminobutyric acid receptor clustering	4.503889e-4
GO:0097117	guanylate kinase-associated protein clustering	4.503889e-4
GO:0032227	negative regulation of synaptic transmission, dopaminergic	4.503889e-4
GO:0014819	regulation of skeletal muscle contraction	4.503889e-4
GO:0001666	response to hypoxia	4.516138e-4
GO:0042921	glucocorticoid receptor signaling pathway	4.541286e-4
GO:0046716	muscle cell homeostasis	4.547396e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	4.617685e-4
GO:0071827	plasma lipoprotein particle organization	4.650366e-4
GO:0003018	vascular process in circulatory system	4.693232e-4
GO:0031589	cell-substrate adhesion	4.724809e-4
GO:0043266	regulation of potassium ion transport	4.748305e-4
GO:0034446	substrate adhesion-dependent cell spreading	4.790847e-4
GO:0050670	regulation of lymphocyte proliferation	4.866302e-4
GO:0051180	vitamin transport	4.916382e-4
GO:0030182	neuron differentiation	5.007817e-4
GO:0030030	cell projection organization	5.132755e-4
GO:0015833	peptide transport	5.139999e-4
GO:0006661	phosphatidylinositol biosynthetic process	5.181276e-4
GO:0001660	fever generation	5.246802e-4
GO:0042307	positive regulation of protein import into nucleus	5.325849e-4
GO:0051823	regulation of synapse structural plasticity	5.449763e-4
GO:0051338	regulation of transferase activity	5.487215e-4
GO:0045723	positive regulation of fatty acid biosynthetic process	5.521299e-4
GO:0007417	central nervous system development	5.533225e-4
GO:0048584	positive regulation of response to stimulus	5.554938e-4
GO:0034201	response to oleic acid	5.565213e-4
GO:0030335	positive regulation of cell migration	5.576671e-4
GO:0042990	regulation of transcription factor import into nucleus	5.613257e-4
GO:0043116	negative regulation of vascular permeability	5.635879e-4
GO:0042345	regulation of NF-kappaB import into nucleus	5.697137e-4
GO:0032329	serine transport	5.794153e-4
GO:0031328	positive regulation of cellular biosynthetic process	5.822734e-4
GO:0030029	actin filament-based process	5.825398e-4
GO:0008104	protein localization	5.874473e-4
GO:0060562	epithelial tube morphogenesis	6.081435e-4
GO:0031960	response to corticosteroid stimulus	6.130322e-4
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	6.131554e-4
GO:0034605	cellular response to heat	6.139271e-4
GO:0097006	regulation of plasma lipoprotein particle levels	6.195421e-4
GO:0007568	aging	6.250425e-4
GO:0015791	polyol transport	6.251683e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010591	regulation of lamellipodium assembly	1.329987e-9
GO:0045919	positive regulation of cytolysis	2.988867e-9
GO:0043519	regulation of myosin II filament organization	1.272751e-8
GO:0005980	glycogen catabolic process	2.033842e-8
GO:0060491	regulation of cell projection assembly	3.969690e-8
GO:0032956	regulation of actin cytoskeleton organization	6.561636e-8
GO:0032970	regulation of actin filament-based process	1.067931e-7
GO:0060998	regulation of dendritic spine development	2.294354e-7
GO:0043380	regulation of memory T cell differentiation	2.883031e-7
GO:0032185	septin cytoskeleton organization	3.535880e-7
GO:0006950	response to stress	4.697189e-7
GO:0035024	negative regulation of Rho protein signal transduction	4.988191e-7
GO:0010592	positive regulation of lamellipodium assembly	5.780448e-7
GO:0009605	response to external stimulus	6.824261e-7
GO:0032764	negative regulation of mast cell cytokine production	7.537905e-7
GO:0048294	negative regulation of isotype switching to IgE isotypes	9.358093e-7
GO:0045321	leukocyte activation	1.171495e-6
GO:0048293	regulation of isotype switching to IgE isotypes	1.637194e-6
GO:0006108	malate metabolic process	2.078179e-6
GO:0042092	type 2 immune response	2.466172e-6
GO:0022604	regulation of cell morphogenesis	2.841141e-6
GO:0009225	nucleotide-sugar metabolic process	2.946280e-6
GO:0000272	polysaccharide catabolic process	3.060800e-6
GO:0015876	acetyl-CoA transport	3.214517e-6
GO:0006810	transport	3.452516e-6
GO:0046395	carboxylic acid catabolic process	3.453634e-6
GO:0042769	DNA damage response, detection of DNA damage	3.632365e-6
GO:0051606	detection of stimulus	4.073292e-6
GO:0050793	regulation of developmental process	4.477558e-6
GO:0000902	cell morphogenesis	4.663896e-6
GO:0048858	cell projection morphogenesis	5.010845e-6
GO:0044282	small molecule catabolic process	5.275302e-6
GO:0030832	regulation of actin filament length	6.078567e-6
GO:0010638	positive regulation of organelle organization	6.141218e-6
GO:0002829	negative regulation of type 2 immune response	6.393989e-6
GO:0045620	negative regulation of lymphocyte differentiation	6.454294e-6
GO:0009063	cellular amino acid catabolic process	6.455114e-6
GO:0051234	establishment of localization	6.710766e-6
GO:0008064	regulation of actin polymerization or depolymerization	7.124148e-6
GO:0050896	response to stimulus	7.132660e-6
GO:0045629	negative regulation of T-helper 2 cell differentiation	7.414804e-6
GO:0032990	cell part morphogenesis	7.629961e-6
GO:0031667	response to nutrient levels	7.974919e-6
GO:0051491	positive regulation of filopodium assembly	8.170600e-6
GO:0044087	regulation of cellular component biogenesis	8.213794e-6
GO:0090276	regulation of peptide hormone secretion	8.306935e-6
GO:0023061	signal release	8.453252e-6
GO:0007584	response to nutrient	9.080839e-6
GO:0031344	regulation of cell projection organization	1.080345e-5
GO:0046826	negative regulation of protein export from nucleus	1.081767e-5
GO:0000103	sulfate assimilation	1.081767e-5
GO:0046639	negative regulation of alpha-beta T cell differentiation	1.095206e-5
GO:0009991	response to extracellular stimulus	1.144631e-5
GO:0051901	positive regulation of mitochondrial depolarization	1.251089e-5
GO:0032763	regulation of mast cell cytokine production	1.251089e-5
GO:0060271	cilium morphogenesis	1.293475e-5
GO:0046649	lymphocyte activation	1.293494e-5
GO:0002791	regulation of peptide secretion	1.333784e-5
GO:0001775	cell activation	1.337057e-5
GO:0046381	CMP-N-acetylneuraminate metabolic process	1.459713e-5
GO:0033043	regulation of organelle organization	1.561763e-5
GO:0060828	regulation of canonical Wnt receptor signaling pathway	1.603444e-5
GO:0065008	regulation of biological quality	1.642202e-5
GO:0007089	traversing start control point of mitotic cell cycle	1.677026e-5
GO:0007596	blood coagulation	1.725838e-5
GO:0048731	system development	1.772764e-5
GO:0030838	positive regulation of actin filament polymerization	1.825852e-5
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.843029e-5
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	1.868979e-5
GO:0007599	hemostasis	2.057945e-5
GO:0010942	positive regulation of cell death	2.094885e-5
GO:0051046	regulation of secretion	2.121417e-5
GO:0045623	negative regulation of T-helper cell differentiation	2.217898e-5
GO:0006040	amino sugar metabolic process	2.234431e-5
GO:0051179	localization	2.324844e-5
GO:0007040	lysosome organization	2.453541e-5
GO:0030890	positive regulation of B cell proliferation	2.484215e-5
GO:0045619	regulation of lymphocyte differentiation	2.517169e-5
GO:0003183	mitral valve morphogenesis	2.704447e-5
GO:0007050	cell cycle arrest	2.783496e-5
GO:0043584	nose development	2.789211e-5
GO:0051493	regulation of cytoskeleton organization	2.799792e-5
GO:0071773	cellular response to BMP stimulus	2.846908e-5
GO:0044262	cellular carbohydrate metabolic process	3.008245e-5
GO:0046580	negative regulation of Ras protein signal transduction	3.029253e-5
GO:0061001	regulation of dendritic spine morphogenesis	3.042161e-5
GO:0021522	spinal cord motor neuron differentiation	3.342345e-5
GO:0045622	regulation of T-helper cell differentiation	3.567873e-5
GO:0006054	N-acetylneuraminate metabolic process	3.608911e-5
GO:0005975	carbohydrate metabolic process	3.722433e-5
GO:0071504	cellular response to heparin	3.945135e-5
GO:0051128	regulation of cellular component organization	4.395835e-5
GO:0048814	regulation of dendrite morphogenesis	4.490164e-5
GO:0061002	negative regulation of dendritic spine morphogenesis	4.605043e-5
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	4.730860e-5
GO:0006605	protein targeting	4.877584e-5
GO:0008360	regulation of cell shape	5.028671e-5
GO:0071503	response to heparin	5.114442e-5
GO:0030030	cell projection organization	5.421642e-5
GO:0043068	positive regulation of programmed cell death	5.487300e-5
GO:0019543	propionate catabolic process	5.609447e-5
GO:0050773	regulation of dendrite development	5.717174e-5
GO:0035567	non-canonical Wnt receptor signaling pathway	5.759161e-5
GO:0018105	peptidyl-serine phosphorylation	5.827606e-5
GO:0034695	response to prostaglandin E stimulus	6.381396e-5
GO:0042119	neutrophil activation	6.381396e-5
GO:0061301	cerebellum vasculature morphogenesis	6.556143e-5
GO:0051495	positive regulation of cytoskeleton organization	6.916760e-5
GO:0042268	regulation of cytolysis	6.972243e-5
GO:0055074	calcium ion homeostasis	7.432054e-5
GO:0046636	negative regulation of alpha-beta T cell activation	7.667355e-5
GO:0050671	positive regulation of lymphocyte proliferation	7.844906e-5
GO:0008285	negative regulation of cell proliferation	8.461708e-5
GO:0048699	generation of neurons	8.584221e-5
GO:0046883	regulation of hormone secretion	8.585351e-5
GO:0030182	neuron differentiation	9.101056e-5
GO:2000756	regulation of peptidyl-lysine acetylation	9.178798e-5
GO:0017157	regulation of exocytosis	9.216852e-5
GO:0005996	monosaccharide metabolic process	9.258568e-5
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	9.292479e-5
GO:2000271	positive regulation of fibroblast apoptosis	9.292479e-5
GO:0070627	ferrous iron import	9.292479e-5
GO:2000270	negative regulation of fibroblast apoptosis	9.292479e-5
GO:0015676	vanadium ion transport	9.292479e-5
GO:0015692	lead ion transport	9.292479e-5
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	9.292479e-5
GO:0010025	wax biosynthetic process	9.331950e-5
GO:0032946	positive regulation of mononuclear cell proliferation	9.477193e-5
GO:0043434	response to peptide hormone stimulus	9.477990e-5
GO:0022008	neurogenesis	9.569187e-5
GO:0051900	regulation of mitochondrial depolarization	9.758249e-5
GO:0051489	regulation of filopodium assembly	1.017424e-4
GO:0046825	regulation of protein export from nucleus	1.019333e-4
GO:0045595	regulation of cell differentiation	1.080000e-4
GO:0009310	amine catabolic process	1.087044e-4
GO:0051899	membrane depolarization	1.089700e-4
GO:0070665	positive regulation of leukocyte proliferation	1.095569e-4
GO:0043065	positive regulation of apoptosis	1.118417e-4
GO:0030111	regulation of Wnt receptor signaling pathway	1.121427e-4
GO:0018209	peptidyl-serine modification	1.144088e-4
GO:0019541	propionate metabolic process	1.181382e-4
GO:0001522	pseudouridine synthesis	1.195286e-4
GO:0060123	regulation of growth hormone secretion	1.210534e-4
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.282815e-4
GO:0071380	cellular response to prostaglandin E stimulus	1.282815e-4
GO:0060341	regulation of cellular localization	1.397653e-4
GO:0060041	retina development in camera-type eye	1.425715e-4
GO:0045580	regulation of T cell differentiation	1.444133e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	1.582701e-4
GO:0097115	neurexin clustering	1.724694e-4
GO:0055065	metal ion homeostasis	1.734543e-4
GO:0044275	cellular carbohydrate catabolic process	1.790656e-4
GO:0006886	intracellular protein transport	1.811851e-4
GO:0046637	regulation of alpha-beta T cell differentiation	1.836047e-4
GO:0007033	vacuole organization	1.918462e-4
GO:0071305	cellular response to vitamin D	1.956251e-4
GO:0043113	receptor clustering	2.103113e-4
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	2.137329e-4
GO:0034694	response to prostaglandin stimulus	2.161828e-4
GO:0007158	neuron cell-cell adhesion	2.205651e-4
GO:0046677	response to antibiotic	2.248807e-4
GO:0016476	regulation of embryonic cell shape	2.251165e-4
GO:0072507	divalent inorganic cation homeostasis	2.323398e-4
GO:0002719	negative regulation of cytokine production involved in immune response	2.324045e-4
GO:0051053	negative regulation of DNA metabolic process	2.400859e-4
GO:0006066	alcohol metabolic process	2.413600e-4
GO:0032501	multicellular organismal process	2.455506e-4
GO:0034435	cholesterol esterification	2.473626e-4
GO:0021543	pallium development	2.485862e-4
GO:0010975	regulation of neuron projection development	2.490025e-4
GO:0006479	protein methylation	2.559973e-4
GO:0045581	negative regulation of T cell differentiation	2.628783e-4
GO:0005978	glycogen biosynthetic process	2.647727e-4
GO:0050775	positive regulation of dendrite morphogenesis	2.716358e-4
GO:0045910	negative regulation of DNA recombination	2.716358e-4
GO:0016052	carbohydrate catabolic process	2.728542e-4
GO:0051927	negative regulation of calcium ion transport via voltage-gated calcium channel activity	2.737415e-4
GO:0072643	interferon-gamma secretion	2.826175e-4
GO:0072608	interleukin-10 secretion	2.826175e-4
GO:0090198	negative regulation of chemokine secretion	2.826175e-4
GO:0043311	positive regulation of eosinophil degranulation	2.826175e-4
GO:0035926	chemokine (C-C motif) ligand 2 secretion	2.826175e-4
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	2.826175e-4
GO:0048856	anatomical structure development	2.885271e-4
GO:0050864	regulation of B cell activation	3.262947e-4
GO:0045664	regulation of neuron differentiation	3.296092e-4
GO:0009083	branched chain family amino acid catabolic process	3.302551e-4
GO:0072657	protein localization in membrane	3.401783e-4
GO:0007399	nervous system development	3.449141e-4
GO:0033674	positive regulation of kinase activity	3.460775e-4
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	3.804593e-4
GO:0032319	regulation of Rho GTPase activity	3.847165e-4
GO:0016042	lipid catabolic process	3.850255e-4
GO:0021537	telencephalon development	3.874623e-4
GO:0048878	chemical homeostasis	3.884843e-4
GO:0051182	coenzyme transport	3.966881e-4
GO:0048522	positive regulation of cellular process	4.108793e-4
GO:0002701	negative regulation of production of molecular mediator of immune response	4.245724e-4
GO:0033143	regulation of steroid hormone receptor signaling pathway	4.386240e-4
GO:2000602	regulation of interphase of mitotic cell cycle	4.521118e-4
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	4.572177e-4
GO:0045191	regulation of isotype switching	4.592219e-4
GO:0010646	regulation of cell communication	4.602311e-4
GO:0060079	regulation of excitatory postsynaptic membrane potential	4.785733e-4
GO:0030098	lymphocyte differentiation	4.882657e-4
GO:0032232	negative regulation of actin filament bundle assembly	4.921232e-4
GO:0021953	central nervous system neuron differentiation	5.242472e-4
GO:0051347	positive regulation of transferase activity	5.314646e-4
GO:0007416	synapse assembly	5.317325e-4
GO:0000018	regulation of DNA recombination	5.322554e-4
GO:0045628	regulation of T-helper 2 cell differentiation	5.404706e-4
GO:0006436	tryptophanyl-tRNA aminoacylation	5.584445e-4
GO:0050796	regulation of insulin secretion	5.646514e-4
GO:0034261	negative regulation of Ras GTPase activity	5.740398e-4
GO:0035023	regulation of Rho protein signal transduction	5.812803e-4
GO:0032273	positive regulation of protein polymerization	5.980374e-4
GO:0051649	establishment of localization in cell	6.137664e-4
GO:0035910	ascending aorta morphogenesis	6.248866e-4
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	6.248866e-4
GO:0045921	positive regulation of exocytosis	6.252226e-4
GO:0016572	histone phosphorylation	6.253563e-4
GO:0007218	neuropeptide signaling pathway	6.364807e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	6.410088e-4
GO:0032989	cellular component morphogenesis	6.489124e-4
GO:0015908	fatty acid transport	6.501494e-4
GO:0061304	retinal blood vessel morphogenesis	6.564344e-4
GO:0070574	cadmium ion transmembrane transport	6.564344e-4
GO:0042110	T cell activation	6.606928e-4
GO:0007204	elevation of cytosolic calcium ion concentration	6.693373e-4
GO:0031960	response to corticosteroid stimulus	7.361745e-4
GO:0060413	atrial septum morphogenesis	7.393415e-4
GO:0060872	semicircular canal development	7.397094e-4
GO:0007275	multicellular organismal development	7.399240e-4
GO:0090317	negative regulation of intracellular protein transport	7.467002e-4
GO:0048518	positive regulation of biological process	7.611245e-4
GO:0046475	glycerophospholipid catabolic process	7.672227e-4
GO:0046323	glucose import	7.672227e-4
GO:0032502	developmental process	7.821526e-4
GO:0007267	cell-cell signaling	8.026117e-4
GO:0045860	positive regulation of protein kinase activity	8.281662e-4
GO:0070727	cellular macromolecule localization	8.286913e-4
GO:0051318	G1 phase	8.380528e-4
GO:0006874	cellular calcium ion homeostasis	8.384885e-4
GO:0042701	progesterone secretion	8.411188e-4
GO:0032879	regulation of localization	8.423443e-4
GO:0048869	cellular developmental process	8.487077e-4
GO:0046928	regulation of neurotransmitter secretion	8.489197e-4
GO:0050869	negative regulation of B cell activation	8.494309e-4
GO:0051971	positive regulation of transmission of nerve impulse	8.790460e-4
GO:0032940	secretion by cell	8.859508e-4
GO:0051251	positive regulation of lymphocyte activation	8.875861e-4
GO:0010033	response to organic substance	8.935943e-4
GO:0060166	olfactory pit development	8.961999e-4
GO:0035444	nickel ion transmembrane transport	8.961999e-4
GO:0030154	cell differentiation	9.071063e-4
GO:0030317	sperm motility	9.088820e-4
GO:0097091	synaptic vesicle clustering	9.163473e-4
GO:0034613	cellular protein localization	9.301177e-4
GO:0030217	T cell differentiation	9.428088e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	9.439882e-4
GO:0031161	phosphatidylinositol catabolic process	9.439882e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	9.439882e-4
GO:0035304	regulation of protein dephosphorylation	9.445906e-4
GO:2000778	positive regulation of interleukin-6 secretion	9.505923e-4
GO:0043549	regulation of kinase activity	9.860164e-4
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	9.892058e-4
GO:0033692	cellular polysaccharide biosynthetic process	1.003720e-3
GO:0001659	temperature homeostasis	1.006692e-3
GO:0048871	multicellular organismal homeostasis	1.053236e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	1.056643e-3
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.077217e-3
GO:0042592	homeostatic process	1.085074e-3
GO:0055080	cation homeostasis	1.097728e-3
GO:0048812	neuron projection morphogenesis	1.101159e-3
GO:0046823	negative regulation of nucleocytoplasmic transport	1.106721e-3
GO:0033554	cellular response to stress	1.154453e-3
GO:0071392	cellular response to estradiol stimulus	1.176193e-3
GO:0051567	histone H3-K9 methylation	1.184404e-3
GO:0001963	synaptic transmission, dopaminergic	1.184441e-3
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	1.191224e-3
GO:0050806	positive regulation of synaptic transmission	1.194373e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	1.194644e-3
GO:0009719	response to endogenous stimulus	1.198760e-3
GO:0048513	organ development	1.205834e-3
GO:0045666	positive regulation of neuron differentiation	1.218496e-3
GO:0032231	regulation of actin filament bundle assembly	1.222221e-3
GO:0042221	response to chemical stimulus	1.240385e-3
GO:0051965	positive regulation of synapse assembly	1.257281e-3
GO:0007417	central nervous system development	1.258708e-3
GO:0009582	detection of abiotic stimulus	1.266312e-3
GO:0046634	regulation of alpha-beta T cell activation	1.270507e-3
GO:0007341	penetration of zona pellucida	1.279838e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	1.293620e-3
GO:0035108	limb morphogenesis	1.310581e-3
GO:0031016	pancreas development	1.328710e-3
GO:0045786	negative regulation of cell cycle	1.339555e-3
GO:0046165	alcohol biosynthetic process	1.341293e-3
GO:0042060	wound healing	1.343219e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	1.390717e-3
GO:0051492	regulation of stress fiber assembly	1.410573e-3
GO:0050871	positive regulation of B cell activation	1.422097e-3
GO:0033146	regulation of estrogen receptor signaling pathway	1.480768e-3
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1.480768e-3
GO:0060840	artery development	1.485602e-3
GO:0097105	presynaptic membrane assembly	1.486274e-3
GO:0031646	positive regulation of neurological system process	1.495575e-3
GO:0042113	B cell activation	1.509087e-3
GO:0048752	semicircular canal morphogenesis	1.512847e-3
GO:0035786	protein complex oligomerization	1.577466e-3
GO:0003289	atrial septum primum morphogenesis	1.591946e-3
GO:0002710	negative regulation of T cell mediated immunity	1.599923e-3
GO:0009725	response to hormone stimulus	1.615764e-3
GO:0003283	atrial septum development	1.625363e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.636858e-3
GO:0006694	steroid biosynthetic process	1.641615e-3
GO:0051338	regulation of transferase activity	1.651117e-3
GO:0048844	artery morphogenesis	1.665223e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.709791e-3
GO:0060284	regulation of cell development	1.763671e-3
GO:0070460	thyroid-stimulating hormone secretion	1.807876e-3
GO:0030888	regulation of B cell proliferation	1.821654e-3
GO:0000080	G1 phase of mitotic cell cycle	1.834592e-3
GO:0044242	cellular lipid catabolic process	1.865091e-3
GO:0048666	neuron development	1.885487e-3
GO:0060173	limb development	1.891905e-3
GO:0071322	cellular response to carbohydrate stimulus	1.899335e-3
GO:0032271	regulation of protein polymerization	1.900323e-3
GO:0097120	receptor localization to synapse	1.924724e-3
GO:0072578	neurotransmitter-gated ion channel clustering	1.924724e-3
GO:0006700	C21-steroid hormone biosynthetic process	1.924724e-3
GO:0046907	intracellular transport	1.960349e-3
GO:0007093	mitotic cell cycle checkpoint	1.963592e-3
GO:0070495	negative regulation of thrombin receptor signaling pathway	1.978717e-3
GO:0051622	negative regulation of norepinephrine uptake	1.978717e-3
GO:0051585	negative regulation of dopamine uptake	1.978717e-3
GO:0050812	regulation of acyl-CoA biosynthetic process	1.978717e-3
GO:0072503	cellular divalent inorganic cation homeostasis	2.005311e-3
GO:0021515	cell differentiation in spinal cord	2.019190e-3
GO:0042127	regulation of cell proliferation	2.021026e-3
GO:0033273	response to vitamin	2.021708e-3
GO:0060766	negative regulation of androgen receptor signaling pathway	2.106253e-3
GO:0060586	multicellular organismal iron ion homeostasis	2.114643e-3
GO:0015684	ferrous iron transport	2.114643e-3
GO:0022603	regulation of anatomical structure morphogenesis	2.134379e-3
GO:0009653	anatomical structure morphogenesis	2.135861e-3
GO:0044089	positive regulation of cellular component biogenesis	2.148288e-3
GO:0010986	positive regulation of lipoprotein particle clearance	2.162436e-3
GO:0071158	positive regulation of cell cycle arrest	2.177614e-3
GO:0097090	presynaptic membrane organization	2.180433e-3
GO:0051224	negative regulation of protein transport	2.200231e-3
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	2.228809e-3
GO:0045578	negative regulation of B cell differentiation	2.253175e-3
GO:0007601	visual perception	2.267475e-3
GO:0060078	regulation of postsynaptic membrane potential	2.317900e-3
GO:0050670	regulation of lymphocyte proliferation	2.417370e-3
GO:0051712	positive regulation of killing of cells of other organism	2.457662e-3
GO:0032387	negative regulation of intracellular transport	2.464121e-3
GO:0010812	negative regulation of cell-substrate adhesion	2.480563e-3
GO:0032535	regulation of cellular component size	2.506309e-3
GO:0051641	cellular localization	2.513508e-3
GO:0009583	detection of light stimulus	2.522969e-3
GO:0048148	behavioral response to cocaine	2.532572e-3
GO:0034637	cellular carbohydrate biosynthetic process	2.548141e-3
GO:0001944	vasculature development	2.629939e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	2.638003e-3
GO:0051057	positive regulation of small GTPase mediated signal transduction	2.641467e-3
GO:0032410	negative regulation of transporter activity	2.672501e-3
GO:0050953	sensory perception of light stimulus	2.679265e-3
GO:0045582	positive regulation of T cell differentiation	2.698106e-3
GO:0045453	bone resorption	2.721760e-3
GO:0032944	regulation of mononuclear cell proliferation	2.727370e-3
GO:0008653	lipopolysaccharide metabolic process	2.737269e-3
GO:0035307	positive regulation of protein dephosphorylation	2.746511e-3
GO:0021517	ventral spinal cord development	2.779276e-3
GO:0007254	JNK cascade	2.828933e-3
GO:0051026	chiasma assembly	2.837180e-3
GO:0035425	autocrine signaling	2.839324e-3
GO:0035426	extracellular matrix-cell signaling	2.839324e-3
GO:0045597	positive regulation of cell differentiation	2.848900e-3
GO:0002643	regulation of tolerance induction	2.861320e-3
GO:0008090	retrograde axon cargo transport	2.864921e-3
GO:0051497	negative regulation of stress fiber assembly	2.864921e-3
GO:0002696	positive regulation of leukocyte activation	2.894696e-3
GO:0002820	negative regulation of adaptive immune response	2.916751e-3
GO:0030178	negative regulation of Wnt receptor signaling pathway	2.926642e-3
GO:0035306	positive regulation of dephosphorylation	2.928656e-3
GO:0009612	response to mechanical stimulus	2.952903e-3
GO:0000086	G2/M transition of mitotic cell cycle	3.003420e-3
GO:0002521	leukocyte differentiation	3.004662e-3
GO:0097029	mature dendritic cell differentiation	3.018235e-3
GO:0046960	sensitization	3.018235e-3
GO:0043309	regulation of eosinophil degranulation	3.018235e-3
GO:0007049	cell cycle	3.029450e-3
GO:0046879	hormone secretion	3.065481e-3
GO:0017158	regulation of calcium ion-dependent exocytosis	3.083162e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.120305e-3
GO:0007155	cell adhesion	3.133130e-3
GO:0002328	pro-B cell differentiation	3.197828e-3
GO:0032024	positive regulation of insulin secretion	3.203525e-3
GO:0070663	regulation of leukocyte proliferation	3.236496e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	3.262024e-3
GO:0060411	cardiac septum morphogenesis	3.278839e-3
GO:0009581	detection of external stimulus	3.311478e-3
GO:0007269	neurotransmitter secretion	3.324895e-3
GO:0071842	cellular component organization at cellular level	3.383080e-3
GO:0071379	cellular response to prostaglandin stimulus	3.426314e-3
GO:0006875	cellular metal ion homeostasis	3.442370e-3
GO:0030833	regulation of actin filament polymerization	3.452890e-3
GO:0031399	regulation of protein modification process	3.505604e-3
GO:0060547	negative regulation of necrotic cell death	3.527534e-3
GO:0016571	histone methylation	3.554783e-3
GO:0051384	response to glucocorticoid stimulus	3.593825e-3
GO:0016051	carbohydrate biosynthetic process	3.616377e-3
GO:0050801	ion homeostasis	3.690532e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	3.728159e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	3.728159e-3
GO:0042446	hormone biosynthetic process	3.738253e-3
GO:0051480	cytosolic calcium ion homeostasis	3.739693e-3
GO:0007154	cell communication	3.786500e-3
GO:0019220	regulation of phosphate metabolic process	3.786966e-3
GO:0022610	biological adhesion	3.804181e-3
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.820925e-3
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	3.887638e-3
GO:0010810	regulation of cell-substrate adhesion	3.893413e-3
GO:0035137	hindlimb morphogenesis	3.905152e-3
GO:0048169	regulation of long-term neuronal synaptic plasticity	3.905306e-3
GO:0034260	negative regulation of GTPase activity	3.926609e-3
GO:0051589	negative regulation of neurotransmitter transport	3.926609e-3
GO:0023052	signaling	3.936840e-3
GO:0006629	lipid metabolic process	3.941929e-3
GO:0050804	regulation of synaptic transmission	3.958286e-3
GO:0044065	regulation of respiratory system process	3.984549e-3
GO:0016080	synaptic vesicle targeting	3.988925e-3
GO:0051249	regulation of lymphocyte activation	4.016403e-3
GO:0051593	response to folic acid	4.038121e-3
GO:0015866	ADP transport	4.054901e-3
GO:0035623	renal glucose absorption	4.054901e-3
GO:0006869	lipid transport	4.107889e-3
GO:0043901	negative regulation of multi-organism process	4.194624e-3
GO:0009743	response to carbohydrate stimulus	4.224416e-3
GO:0060687	regulation of branching involved in prostate gland morphogenesis	4.233381e-3
GO:0033157	regulation of intracellular protein transport	4.261995e-3
GO:0097022	lymphocyte migration into lymph node	4.286647e-3
GO:0072610	interleukin-12 secretion	4.286647e-3
GO:0001692	histamine metabolic process	4.286647e-3
GO:0006851	mitochondrial calcium ion transport	4.286647e-3
GO:0043648	dicarboxylic acid metabolic process	4.329889e-3
GO:0007042	lysosomal lumen acidification	4.335379e-3
GO:0002649	regulation of tolerance induction to self antigen	4.335379e-3
GO:2000026	regulation of multicellular organismal development	4.425441e-3
GO:0051051	negative regulation of transport	4.433931e-3
GO:0035556	intracellular signal transduction	4.523495e-3
GO:0097104	postsynaptic membrane assembly	4.591170e-3
GO:0097119	postsynaptic density protein 95 clustering	4.591170e-3
GO:0002244	hemopoietic progenitor cell differentiation	4.599816e-3
GO:0002087	regulation of respiratory gaseous exchange by neurological system process	4.602561e-3
GO:0045859	regulation of protein kinase activity	4.620966e-3
GO:0060159	regulation of dopamine receptor signaling pathway	4.650915e-3
GO:0050777	negative regulation of immune response	4.688819e-3
GO:0007628	adult walking behavior	4.735409e-3
GO:0051048	negative regulation of secretion	4.750567e-3
GO:0001915	negative regulation of T cell mediated cytotoxicity	4.757638e-3
GO:0097070	ductus arteriosus closure	4.786880e-3
GO:0070314	G1 to G0 transition	4.800256e-3
GO:0051612	negative regulation of serotonin uptake	4.800256e-3
GO:0016050	vesicle organization	4.811596e-3
GO:0002698	negative regulation of immune effector process	4.833449e-3
GO:0002467	germinal center formation	4.840997e-3
GO:0060412	ventricular septum morphogenesis	4.889400e-3
GO:0051588	regulation of neurotransmitter transport	4.905225e-3
GO:0021987	cerebral cortex development	4.924147e-3
GO:0050867	positive regulation of cell activation	4.984384e-3
GO:0034383	low-density lipoprotein particle clearance	5.018843e-3
GO:0050767	regulation of neurogenesis	5.036181e-3
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	5.036766e-3
GO:0071295	cellular response to vitamin	5.041101e-3
GO:0035019	somatic stem cell maintenance	5.045193e-3
GO:0097026	dendritic cell dendrite assembly	5.063301e-3
GO:0006438	valyl-tRNA aminoacylation	5.063301e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	5.078940e-3
GO:0031017	exocrine pancreas development	5.109680e-3
GO:0031400	negative regulation of protein modification process	5.114000e-3
GO:0001952	regulation of cell-matrix adhesion	5.240143e-3
GO:0070848	response to growth factor stimulus	5.266194e-3
GO:0071481	cellular response to X-ray	5.271983e-3
GO:0032602	chemokine production	5.282753e-3
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	5.282753e-3
GO:0016043	cellular component organization	5.283249e-3
GO:0051329	interphase of mitotic cell cycle	5.445124e-3
GO:0016339	calcium-dependent cell-cell adhesion	5.452610e-3
GO:0008202	steroid metabolic process	5.476804e-3
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	5.511085e-3
GO:0022615	protein to membrane docking	5.511085e-3
GO:0014009	glial cell proliferation	5.523034e-3
GO:0001649	osteoblast differentiation	5.537746e-3
GO:0033993	response to lipid	5.594475e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.653884e-3
GO:0031175	neuron projection development	5.700928e-3
GO:0051047	positive regulation of secretion	5.704059e-3
GO:0065009	regulation of molecular function	5.727850e-3