Novel motif:131

name:	motif131_CTGCTTAAATA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032971	regulation of muscle filament sliding	1.778662e-16
GO:0003012	muscle system process	6.152723e-15
GO:0006936	muscle contraction	1.494011e-14
GO:0003008	system process	1.399588e-12
GO:0048087	positive regulation of developmental pigmentation	3.106395e-10
GO:0030049	muscle filament sliding	3.816282e-10
GO:0070252	actin-mediated cell contraction	4.623952e-10
GO:0007517	muscle organ development	1.235449e-9
GO:0045636	positive regulation of melanocyte differentiation	1.333894e-9
GO:0045634	regulation of melanocyte differentiation	2.770723e-9
GO:0045047	protein targeting to ER	3.262179e-9
GO:0032781	positive regulation of ATPase activity	1.244845e-8
GO:0060047	heart contraction	1.437444e-8
GO:0010817	regulation of hormone levels	1.922451e-8
GO:0009235	cobalamin metabolic process	2.523187e-8
GO:0042574	retinal metabolic process	3.048118e-8
GO:0046660	female sex differentiation	3.067534e-8
GO:0006620	posttranslational protein targeting to membrane	3.072925e-8
GO:0046545	development of primary female sexual characteristics	3.677288e-8
GO:0030048	actin filament-based movement	4.151290e-8
GO:0051234	establishment of localization	5.046528e-8
GO:0043616	keratinocyte proliferation	6.780421e-8
GO:0001662	behavioral fear response	7.110086e-8
GO:0008585	female gonad development	7.165348e-8
GO:0002209	behavioral defense response	1.007022e-7
GO:0015889	cobalamin transport	1.113262e-7
GO:0032981	mitochondrial respiratory chain complex I assembly	1.171152e-7
GO:0006810	transport	1.202635e-7
GO:0061061	muscle structure development	1.587954e-7
GO:0060537	muscle tissue development	1.696404e-7
GO:0051179	localization	2.011089e-7
GO:0007344	pronuclear fusion	2.267026e-7
GO:0043004	cytoplasmic sequestering of CFTR protein	2.572337e-7
GO:0022602	ovulation cycle process	2.629976e-7
GO:0048070	regulation of developmental pigmentation	2.917662e-7
GO:0001541	ovarian follicle development	3.078399e-7
GO:0006893	Golgi to plasma membrane transport	3.659176e-7
GO:0006082	organic acid metabolic process	4.675750e-7
GO:0014706	striated muscle tissue development	5.355545e-7
GO:0042596	fear response	5.712058e-7
GO:0042698	ovulation cycle	5.783972e-7
GO:0042180	cellular ketone metabolic process	5.802493e-7
GO:0061039	ovum-producing ovary development	6.652937e-7
GO:0003015	heart process	7.150231e-7
GO:0060048	cardiac muscle contraction	8.464522e-7
GO:0001676	long-chain fatty acid metabolic process	9.127581e-7
GO:0033108	mitochondrial respiratory chain complex assembly	9.356590e-7
GO:0045137	development of primary sexual characteristics	1.067345e-6
GO:0032386	regulation of intracellular transport	1.364508e-6
GO:0019752	carboxylic acid metabolic process	1.917183e-6
GO:0007525	somatic muscle development	2.163980e-6
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	2.351417e-6
GO:0065008	regulation of biological quality	2.937018e-6
GO:0007218	neuropeptide signaling pathway	3.068536e-6
GO:0070972	protein localization in endoplasmic reticulum	3.103593e-6
GO:0048608	reproductive structure development	3.537722e-6
GO:0030029	actin filament-based process	3.570059e-6
GO:0045671	negative regulation of osteoclast differentiation	3.587665e-6
GO:0048468	cell development	3.588168e-6
GO:0050906	detection of stimulus involved in sensory perception	3.859303e-6
GO:0006941	striated muscle contraction	4.940324e-6
GO:0051606	detection of stimulus	5.198586e-6
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	5.840027e-6
GO:0042391	regulation of membrane potential	6.511087e-6
GO:0042759	long-chain fatty acid biosynthetic process	8.225223e-6
GO:0008406	gonad development	8.982730e-6
GO:0045019	negative regulation of nitric oxide biosynthetic process	9.208637e-6
GO:0051205	protein insertion into membrane	9.573552e-6
GO:0048692	negative regulation of axon extension involved in regeneration	9.842582e-6
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	1.050541e-5
GO:0006892	post-Golgi vesicle-mediated transport	1.206199e-5
GO:0050877	neurological system process	1.224540e-5
GO:0060986	endocrine hormone secretion	1.254563e-5
GO:0048738	cardiac muscle tissue development	1.288450e-5
GO:0032970	regulation of actin filament-based process	1.317099e-5
GO:0016358	dendrite development	1.338425e-5
GO:0045428	regulation of nitric oxide biosynthetic process	1.428951e-5
GO:0007016	cytoskeletal anchoring at plasma membrane	1.645418e-5
GO:0006895	Golgi to endosome transport	1.794688e-5
GO:0070293	renal absorption	1.845995e-5
GO:0006081	cellular aldehyde metabolic process	1.884960e-5
GO:0051493	regulation of cytoskeleton organization	1.890715e-5
GO:0035270	endocrine system development	1.995187e-5
GO:0033555	multicellular organismal response to stress	2.037984e-5
GO:0034983	peptidyl-lysine deacetylation	2.119070e-5
GO:0022607	cellular component assembly	2.205402e-5
GO:0048511	rhythmic process	2.406806e-5
GO:0071258	cellular response to gravity	2.557087e-5
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	2.557087e-5
GO:0061044	negative regulation of vascular wound healing	2.557087e-5
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	2.557087e-5
GO:0019228	regulation of action potential in neuron	2.621756e-5
GO:0035644	phosphoanandamide dephosphorylation	2.639721e-5
GO:0046686	response to cadmium ion	2.905671e-5
GO:0055007	cardiac muscle cell differentiation	3.301170e-5
GO:0055008	cardiac muscle tissue morphogenesis	3.315920e-5
GO:0034621	cellular macromolecular complex subunit organization	3.452637e-5
GO:0032272	negative regulation of protein polymerization	3.894569e-5
GO:0071635	negative regulation of transforming growth factor beta production	3.899438e-5
GO:0090026	positive regulation of monocyte chemotaxis	3.910245e-5
GO:0050886	endocrine process	3.985448e-5
GO:0031113	regulation of microtubule polymerization	3.995158e-5
GO:0006776	vitamin A metabolic process	4.018197e-5
GO:0044085	cellular component biogenesis	4.058467e-5
GO:0051047	positive regulation of secretion	4.191687e-5
GO:0009225	nucleotide-sugar metabolic process	4.236436e-5
GO:0007610	behavior	4.347902e-5
GO:0007548	sex differentiation	4.454153e-5
GO:0031115	negative regulation of microtubule polymerization	4.462189e-5
GO:0008015	blood circulation	4.493257e-5
GO:0070932	histone H3 deacetylation	4.499414e-5
GO:0071844	cellular component assembly at cellular level	4.609519e-5
GO:0007160	cell-matrix adhesion	4.760641e-5
GO:0034501	protein localization to kinetochore	4.873524e-5
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	4.895361e-5
GO:0043933	macromolecular complex subunit organization	5.070329e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	5.461134e-5
GO:0010463	mesenchymal cell proliferation	5.641613e-5
GO:0019276	UDP-N-acetylgalactosamine metabolic process	5.674151e-5
GO:0045176	apical protein localization	5.705707e-5
GO:0042445	hormone metabolic process	5.860595e-5
GO:0032886	regulation of microtubule-based process	6.148614e-5
GO:0030259	lipid glycosylation	6.355674e-5
GO:0030832	regulation of actin filament length	6.655717e-5
GO:0044281	small molecule metabolic process	6.722736e-5
GO:0060453	regulation of gastric acid secretion	7.043490e-5
GO:0043473	pigmentation	7.221921e-5
GO:0050794	regulation of cellular process	7.384985e-5
GO:0042701	progesterone secretion	7.767758e-5
GO:0015840	urea transport	8.536055e-5
GO:0043001	Golgi to plasma membrane protein transport	8.606988e-5
GO:0060638	mesenchymal-epithelial cell signaling	9.088892e-5
GO:0046398	UDP-glucuronate metabolic process	9.322188e-5
GO:0015705	iodide transport	9.497439e-5
GO:0048496	maintenance of organ identity	9.670570e-5
GO:0090066	regulation of anatomical structure size	9.909253e-5
GO:0051668	localization within membrane	1.000807e-4
GO:0002282	microglial cell activation involved in immune response	1.032458e-4
GO:0050908	detection of light stimulus involved in visual perception	1.049594e-4
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	1.088226e-4
GO:0018027	peptidyl-lysine dimethylation	1.093127e-4
GO:0014826	vein smooth muscle contraction	1.101719e-4
GO:0034332	adherens junction organization	1.130994e-4
GO:0007321	sperm displacement	1.160325e-4
GO:0022900	electron transport chain	1.164401e-4
GO:0042572	retinol metabolic process	1.186313e-4
GO:0019233	sensory perception of pain	1.211582e-4
GO:0001508	regulation of action potential	1.257124e-4
GO:0032430	positive regulation of phospholipase A2 activity	1.362867e-4
GO:0032431	activation of phospholipase A2 activity	1.390973e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.394884e-4
GO:0005978	glycogen biosynthetic process	1.415794e-4
GO:0048644	muscle organ morphogenesis	1.439967e-4
GO:0042127	regulation of cell proliferation	1.453676e-4
GO:0031110	regulation of microtubule polymerization or depolymerization	1.469615e-4
GO:0006590	thyroid hormone generation	1.477056e-4
GO:0035929	steroid hormone secretion	1.490799e-4
GO:0048753	pigment granule organization	1.512937e-4
GO:0051450	myoblast proliferation	1.513589e-4
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	1.513840e-4
GO:0048610	cellular process involved in reproduction	1.527023e-4
GO:0003013	circulatory system process	1.573682e-4
GO:0032929	negative regulation of superoxide anion generation	1.584501e-4
GO:0030834	regulation of actin filament depolymerization	1.592799e-4
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.628975e-4
GO:0030185	nitric oxide transport	1.628975e-4
GO:0045933	positive regulation of muscle contraction	1.667082e-4
GO:0033692	cellular polysaccharide biosynthetic process	1.774315e-4
GO:0050729	positive regulation of inflammatory response	1.789306e-4
GO:0006857	oligopeptide transport	1.799166e-4
GO:0031018	endocrine pancreas development	1.817753e-4
GO:0051050	positive regulation of transport	1.824658e-4
GO:0035721	intraflagellar retrograde transport	1.931426e-4
GO:0019229	regulation of vasoconstriction	1.933750e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	1.941482e-4
GO:0032802	low-density lipoprotein particle receptor catabolic process	1.965990e-4
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1.973299e-4
GO:0008284	positive regulation of cell proliferation	1.979824e-4
GO:0007267	cell-cell signaling	1.997750e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.001003e-4
GO:0010172	embryonic body morphogenesis	2.031984e-4
GO:0071360	cellular response to exogenous dsRNA	2.049173e-4
GO:0060415	muscle tissue morphogenesis	2.064436e-4
GO:0051494	negative regulation of cytoskeleton organization	2.106051e-4
GO:0000271	polysaccharide biosynthetic process	2.113606e-4
GO:0002576	platelet degranulation	2.121279e-4
GO:0016197	endosome transport	2.159495e-4
GO:0051180	vitamin transport	2.198579e-4
GO:0034754	cellular hormone metabolic process	2.220339e-4
GO:0014824	artery smooth muscle contraction	2.226991e-4
GO:0070933	histone H4 deacetylation	2.236276e-4
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	2.263750e-4
GO:0006801	superoxide metabolic process	2.285547e-4
GO:0034346	positive regulation of type III interferon production	2.318246e-4
GO:0031117	positive regulation of microtubule depolymerization	2.318246e-4
GO:0051153	regulation of striated muscle cell differentiation	2.339940e-4
GO:0048193	Golgi vesicle transport	2.468509e-4
GO:0003058	hormonal regulation of the force of heart contraction	2.544617e-4
GO:0009914	hormone transport	2.599044e-4
GO:0050793	regulation of developmental process	2.609061e-4
GO:0051966	regulation of synaptic transmission, glutamatergic	2.628326e-4
GO:0071822	protein complex subunit organization	2.663864e-4
GO:0033157	regulation of intracellular protein transport	2.667241e-4
GO:0031345	negative regulation of cell projection organization	2.671142e-4
GO:0015793	glycerol transport	2.713097e-4
GO:0031589	cell-substrate adhesion	2.726098e-4
GO:0045749	negative regulation of S phase of mitotic cell cycle	2.830760e-4
GO:0060341	regulation of cellular localization	2.977730e-4
GO:0032501	multicellular organismal process	2.992399e-4
GO:0045930	negative regulation of mitotic cell cycle	2.994115e-4
GO:0051641	cellular localization	3.045681e-4
GO:0031124	mRNA 3'-end processing	3.165835e-4
GO:0019083	viral transcription	3.177166e-4
GO:0016043	cellular component organization	3.263953e-4
GO:0032438	melanosome organization	3.314435e-4
GO:0032787	monocarboxylic acid metabolic process	3.355984e-4
GO:0006415	translational termination	3.366455e-4
GO:0043624	cellular protein complex disassembly	3.486462e-4
GO:0006942	regulation of striated muscle contraction	3.532597e-4
GO:0070294	renal sodium ion absorption	3.688131e-4
GO:0048857	neural nucleus development	3.712352e-4
GO:0006582	melanin metabolic process	3.799209e-4
GO:0009593	detection of chemical stimulus	3.877012e-4
GO:0007015	actin filament organization	3.895006e-4
GO:0055013	cardiac muscle cell development	4.105375e-4
GO:0030835	negative regulation of actin filament depolymerization	4.116115e-4
GO:0046879	hormone secretion	4.362788e-4
GO:0060916	mesenchymal cell proliferation involved in lung development	4.381837e-4
GO:0006775	fat-soluble vitamin metabolic process	4.417041e-4
GO:0006595	polyamine metabolic process	4.431474e-4
GO:0031112	positive regulation of microtubule polymerization or depolymerization	4.431474e-4
GO:0048681	negative regulation of axon regeneration	4.448282e-4
GO:0045072	regulation of interferon-gamma biosynthetic process	4.477370e-4
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	4.482761e-4
GO:0032271	regulation of protein polymerization	4.681183e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	4.842450e-4
GO:0006690	icosanoid metabolic process	5.035539e-4
GO:0044255	cellular lipid metabolic process	5.077466e-4
GO:0051239	regulation of multicellular organismal process	5.222613e-4
GO:0043462	regulation of ATPase activity	5.271277e-4
GO:0045987	positive regulation of smooth muscle contraction	5.295327e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	5.359626e-4
GO:0090322	regulation of superoxide metabolic process	5.430395e-4
GO:0019722	calcium-mediated signaling	5.467191e-4
GO:0071840	cellular component organization or biogenesis	5.623486e-4
GO:0015911	plasma membrane long-chain fatty acid transport	5.628290e-4
GO:0006629	lipid metabolic process	5.754503e-4
GO:0050789	regulation of biological process	5.805483e-4
GO:0042758	long-chain fatty acid catabolic process	5.816906e-4
GO:0042413	carnitine catabolic process	5.816906e-4
GO:0042073	intraflagellar transport	5.816906e-4
GO:0035456	response to interferon-beta	5.830202e-4
GO:0032535	regulation of cellular component size	5.923233e-4
GO:0044057	regulation of system process	5.946135e-4
GO:0050690	regulation of defense response to virus by virus	5.979273e-4
GO:0010966	regulation of phosphate transport	6.003162e-4
GO:0051583	dopamine uptake	6.003162e-4
GO:0021629	olfactory nerve structural organization	6.122791e-4
GO:0030206	chondroitin sulfate biosynthetic process	6.157001e-4
GO:0001523	retinoid metabolic process	6.165283e-4
GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling	6.320408e-4
GO:0032911	negative regulation of transforming growth factor beta1 production	6.320408e-4
GO:0032429	regulation of phospholipase A2 activity	6.347952e-4
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	6.474077e-4
GO:0061029	eyelid development in camera-type eye	6.558428e-4
GO:0006811	ion transport	6.683609e-4
GO:0034622	cellular macromolecular complex assembly	6.786742e-4
GO:0050869	negative regulation of B cell activation	7.014896e-4
GO:0048769	sarcomerogenesis	7.027391e-4
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	7.153094e-4
GO:0019747	regulation of isoprenoid metabolic process	7.283190e-4
GO:0048634	regulation of muscle organ development	7.417034e-4
GO:0043900	regulation of multi-organism process	7.454849e-4
GO:0060045	positive regulation of cardiac muscle cell proliferation	7.517016e-4
GO:0015850	organic alcohol transport	7.540924e-4
GO:0008105	asymmetric protein localization	7.641205e-4
GO:0030889	negative regulation of B cell proliferation	7.722273e-4
GO:0007638	mechanosensory behavior	7.933976e-4
GO:0070507	regulation of microtubule cytoskeleton organization	7.979976e-4
GO:0043241	protein complex disassembly	7.995070e-4
GO:0065003	macromolecular complex assembly	8.059993e-4
GO:0071354	cellular response to interleukin-6	8.068790e-4
GO:0000730	DNA recombinase assembly	8.124566e-4
GO:0065007	biological regulation	8.249679e-4
GO:0014889	muscle atrophy	8.257766e-4
GO:0030204	chondroitin sulfate metabolic process	8.290946e-4
GO:0045823	positive regulation of heart contraction	8.290946e-4
GO:0045359	positive regulation of interferon-beta biosynthetic process	8.316979e-4
GO:0032757	positive regulation of interleukin-8 production	8.322639e-4
GO:0042438	melanin biosynthetic process	8.371675e-4
GO:0045740	positive regulation of DNA replication	8.434674e-4
GO:0045590	negative regulation of regulatory T cell differentiation	8.463573e-4
GO:0032940	secretion by cell	8.563155e-4
GO:0045354	regulation of interferon-alpha biosynthetic process	8.600180e-4
GO:0019226	transmission of nerve impulse	8.729327e-4
GO:0060420	regulation of heart growth	8.738522e-4
GO:0044272	sulfur compound biosynthetic process	8.752549e-4
GO:2000009	negative regulation of protein localization at cell surface	9.293974e-4
GO:0007600	sensory perception	9.407550e-4
GO:0014823	response to activity	9.477425e-4
GO:0051704	multi-organism process	9.478064e-4
GO:0035418	protein localization to synapse	9.601193e-4
GO:0035457	cellular response to interferon-alpha	9.635673e-4
GO:0052572	response to host immune response	9.635673e-4
GO:0070295	renal water absorption	9.818781e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	9.842639e-4
GO:0034623	cellular macromolecular complex disassembly	9.846861e-4
GO:0048813	dendrite morphogenesis	9.937461e-4
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	1.009281e-3
GO:0030030	cell projection organization	1.014697e-3
GO:0070571	negative regulation of neuron projection regeneration	1.019293e-3
GO:0042407	cristae formation	1.021233e-3
GO:0015721	bile acid and bile salt transport	1.030240e-3
GO:0016202	regulation of striated muscle tissue development	1.054158e-3
GO:0006824	cobalt ion transport	1.080702e-3
GO:0048690	regulation of axon extension involved in regeneration	1.084825e-3
GO:0046903	secretion	1.095331e-3
GO:0031943	regulation of glucocorticoid metabolic process	1.124010e-3
GO:0033559	unsaturated fatty acid metabolic process	1.128977e-3
GO:0042742	defense response to bacterium	1.147479e-3
GO:0010977	negative regulation of neuron projection development	1.147893e-3
GO:0031123	RNA 3'-end processing	1.177327e-3
GO:0045357	regulation of interferon-beta biosynthetic process	1.193858e-3
GO:0046058	cAMP metabolic process	1.216960e-3
GO:0006631	fatty acid metabolic process	1.220244e-3
GO:0006119	oxidative phosphorylation	1.228684e-3
GO:0022904	respiratory electron transport chain	1.231491e-3
GO:0003006	developmental process involved in reproduction	1.231810e-3
GO:0006633	fatty acid biosynthetic process	1.241751e-3
GO:0007268	synaptic transmission	1.250914e-3
GO:0009072	aromatic amino acid family metabolic process	1.280079e-3
GO:0043402	glucocorticoid mediated signaling pathway	1.280126e-3
GO:0010838	positive regulation of keratinocyte proliferation	1.282218e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	1.282218e-3
GO:0007565	female pregnancy	1.285916e-3
GO:0033605	positive regulation of catecholamine secretion	1.297604e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	1.307977e-3
GO:0015904	tetracycline transport	1.329444e-3
GO:0006928	cellular component movement	1.387636e-3
GO:0016101	diterpenoid metabolic process	1.399463e-3
GO:0060486	Clara cell differentiation	1.430058e-3
GO:0045589	regulation of regulatory T cell differentiation	1.435818e-3
GO:0051495	positive regulation of cytoskeleton organization	1.436082e-3
GO:0042552	myelination	1.438287e-3
GO:0071286	cellular response to magnesium ion	1.443056e-3
GO:0030325	adrenal gland development	1.458205e-3
GO:0033059	cellular pigmentation	1.459888e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.468259e-3
GO:0051651	maintenance of location in cell	1.500447e-3
GO:0002281	macrophage activation involved in immune response	1.526379e-3
GO:0045091	regulation of retroviral genome replication	1.526379e-3
GO:0003096	renal sodium ion transport	1.535058e-3
GO:0045616	regulation of keratinocyte differentiation	1.541189e-3
GO:0046456	icosanoid biosynthetic process	1.547685e-3
GO:0045595	regulation of cell differentiation	1.553873e-3
GO:0006720	isoprenoid metabolic process	1.568765e-3
GO:0006744	ubiquinone biosynthetic process	1.570593e-3
GO:0042274	ribosomal small subunit biogenesis	1.571536e-3
GO:0032101	regulation of response to external stimulus	1.595059e-3
GO:0009067	aspartate family amino acid biosynthetic process	1.633646e-3
GO:0008152	metabolic process	1.659078e-3
GO:0018026	peptidyl-lysine monomethylation	1.660129e-3
GO:0045213	neurotransmitter receptor metabolic process	1.678762e-3
GO:0045844	positive regulation of striated muscle tissue development	1.699100e-3
GO:0001774	microglial cell activation	1.705183e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.731836e-3
GO:0032647	regulation of interferon-alpha production	1.745059e-3
GO:0042403	thyroid hormone metabolic process	1.745344e-3
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1.758906e-3
GO:0014038	regulation of Schwann cell differentiation	1.785810e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	1.786639e-3
GO:0051649	establishment of localization in cell	1.804577e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	1.833848e-3
GO:0070861	regulation of protein exit from endoplasmic reticulum	1.834387e-3
GO:0008272	sulfate transport	1.834525e-3
GO:0010460	positive regulation of heart rate	1.855229e-3
GO:0032507	maintenance of protein location in cell	1.885786e-3
GO:0009268	response to pH	1.885988e-3
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.886239e-3
GO:0046640	regulation of alpha-beta T cell proliferation	1.893040e-3
GO:0048066	developmental pigmentation	1.897394e-3
GO:0006520	cellular amino acid metabolic process	1.905212e-3
GO:0019254	carnitine metabolic process, CoA-linked	1.912376e-3
GO:0060538	skeletal muscle organ development	1.920097e-3
GO:0006171	cAMP biosynthetic process	1.932258e-3
GO:0043242	negative regulation of protein complex disassembly	1.935258e-3
GO:0032984	macromolecular complex disassembly	1.937920e-3
GO:0035051	cardiac cell differentiation	1.944210e-3
GO:0048565	digestive tract development	1.965684e-3
GO:0030261	chromosome condensation	1.966762e-3
GO:0031016	pancreas development	1.982165e-3
GO:0009597	detection of virus	1.993600e-3
GO:0070663	regulation of leukocyte proliferation	1.999306e-3
GO:0051716	cellular response to stimulus	2.015330e-3
GO:0045426	quinone cofactor biosynthetic process	2.040820e-3
GO:0051272	positive regulation of cellular component movement	2.050985e-3
GO:0060021	palate development	2.077624e-3
GO:0031349	positive regulation of defense response	2.083152e-3
GO:0022414	reproductive process	2.085599e-3
GO:0043438	acetoacetic acid metabolic process	2.093204e-3
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	2.147848e-3
GO:0021740	principal sensory nucleus of trigeminal nerve development	2.147848e-3
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	2.147848e-3
GO:0046898	response to cycloheximide	2.147848e-3
GO:0061141	lung ciliated cell differentiation	2.147848e-3
GO:0034123	positive regulation of toll-like receptor signaling pathway	2.155047e-3
GO:0043252	sodium-independent organic anion transport	2.185561e-3
GO:0008207	C21-steroid hormone metabolic process	2.192352e-3
GO:0021553	olfactory nerve development	2.196551e-3
GO:0050774	negative regulation of dendrite morphogenesis	2.211828e-3
GO:0014821	phasic smooth muscle contraction	2.262384e-3
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	2.332507e-3
GO:0001300	chronological cell aging	2.345402e-3
GO:0015734	taurine transport	2.370230e-3
GO:0000003	reproduction	2.451611e-3
GO:0007611	learning or memory	2.457185e-3
GO:0070253	somatostatin secretion	2.460961e-3
GO:0045234	protein palmitoleylation	2.460961e-3
GO:0006948	induction by virus of host cell-cell fusion	2.460961e-3
GO:0032812	positive regulation of epinephrine secretion	2.460961e-3
GO:0050885	neuromuscular process controlling balance	2.468920e-3
GO:0043585	nose morphogenesis	2.539076e-3
GO:0030035	microspike assembly	2.561162e-3
GO:2000008	regulation of protein localization at cell surface	2.565991e-3
GO:0006091	generation of precursor metabolites and energy	2.597068e-3
GO:0019585	glucuronate metabolic process	2.615632e-3
GO:0006011	UDP-glucose metabolic process	2.618426e-3
GO:0015711	organic anion transport	2.620944e-3
GO:0048169	regulation of long-term neuronal synaptic plasticity	2.635596e-3
GO:0072593	reactive oxygen species metabolic process	2.673071e-3
GO:0006065	UDP-glucuronate biosynthetic process	2.689137e-3
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	2.716473e-3
GO:0044030	regulation of DNA methylation	2.738098e-3
GO:0046394	carboxylic acid biosynthetic process	2.747946e-3
GO:0050999	regulation of nitric-oxide synthase activity	2.748691e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	2.758563e-3
GO:0071842	cellular component organization at cellular level	2.759011e-3
GO:0007252	I-kappaB phosphorylation	2.761252e-3
GO:0032880	regulation of protein localization	2.761998e-3
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	2.821148e-3
GO:0045429	positive regulation of nitric oxide biosynthetic process	2.831540e-3
GO:0009086	methionine biosynthetic process	2.885023e-3
GO:0071780	mitotic cell cycle G2/M transition checkpoint	2.929930e-3
GO:0015791	polyol transport	3.007722e-3
GO:0060510	Type II pneumocyte differentiation	3.007722e-3
GO:0060249	anatomical structure homeostasis	3.009156e-3
GO:0072594	establishment of protein localization to organelle	3.011222e-3
GO:0002690	positive regulation of leukocyte chemotaxis	3.078593e-3
GO:0010611	regulation of cardiac muscle hypertrophy	3.106739e-3
GO:0050688	regulation of defense response to virus	3.135849e-3
GO:0030033	microvillus assembly	3.139718e-3
GO:0046546	development of primary male sexual characteristics	3.141047e-3
GO:0002065	columnar/cuboidal epithelial cell differentiation	3.164807e-3
GO:0021955	central nervous system neuron axonogenesis	3.236671e-3
GO:0048246	macrophage chemotaxis	3.240890e-3
GO:0006766	vitamin metabolic process	3.241096e-3
GO:0050890	cognition	3.243721e-3
GO:0043179	rhythmic excitation	3.256769e-3
GO:0007076	mitotic chromosome condensation	3.258093e-3
GO:0051341	regulation of oxidoreductase activity	3.265245e-3
GO:0051155	positive regulation of striated muscle cell differentiation	3.306833e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.311316e-3
GO:0009308	amine metabolic process	3.315812e-3
GO:0021768	nucleus accumbens development	3.330923e-3
GO:0046849	bone remodeling	3.336630e-3
GO:0048742	regulation of skeletal muscle fiber development	3.340990e-3
GO:0045683	negative regulation of epidermis development	3.346505e-3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	3.363046e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	3.372536e-3
GO:0055114	oxidation-reduction process	3.430512e-3
GO:0046620	regulation of organ growth	3.487972e-3
GO:0045333	cellular respiration	3.515491e-3
GO:0006636	unsaturated fatty acid biosynthetic process	3.548111e-3
GO:0070741	response to interleukin-6	3.571723e-3
GO:0060166	olfactory pit development	3.573346e-3
GO:0001920	negative regulation of receptor recycling	3.590084e-3
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3.594336e-3
GO:0008366	axon ensheathment	3.596238e-3
GO:0044270	cellular nitrogen compound catabolic process	3.623026e-3
GO:0048679	regulation of axon regeneration	3.632532e-3
GO:0042981	regulation of apoptosis	3.653137e-3
GO:0051693	actin filament capping	3.673541e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	3.687800e-3
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	3.773122e-3
GO:0050902	leukocyte adhesive activation	3.773122e-3
GO:0050801	ion homeostasis	3.853527e-3
GO:0019430	removal of superoxide radicals	3.875080e-3
GO:0030241	skeletal muscle myosin thick filament assembly	3.904629e-3
GO:0070271	protein complex biogenesis	3.980408e-3
GO:0051491	positive regulation of filopodium assembly	3.991598e-3
GO:0045730	respiratory burst	3.996505e-3
GO:0014032	neural crest cell development	4.029459e-3
GO:0019058	viral infectious cycle	4.073771e-3
GO:0055082	cellular chemical homeostasis	4.075244e-3
GO:0050727	regulation of inflammatory response	4.089368e-3
GO:0015833	peptide transport	4.137530e-3
GO:0045356	positive regulation of interferon-alpha biosynthetic process	4.217041e-3
GO:0016051	carbohydrate biosynthetic process	4.232173e-3
GO:0018022	peptidyl-lysine methylation	4.238368e-3
GO:0006040	amino sugar metabolic process	4.250166e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006581	acetylcholine catabolic process	4.666039e-20
GO:0008291	acetylcholine metabolic process	9.160260e-20
GO:0045212	neurotransmitter receptor biosynthetic process	6.073974e-18
GO:0042402	cellular biogenic amine catabolic process	5.880850e-17
GO:0032800	receptor biosynthetic process	2.405774e-13
GO:0045213	neurotransmitter receptor metabolic process	4.947825e-13
GO:0042135	neurotransmitter catabolic process	4.417730e-10
GO:0007271	synaptic transmission, cholinergic	1.094870e-9
GO:0007595	lactation	1.789152e-9
GO:0019695	choline metabolic process	1.960174e-9
GO:0016192	vesicle-mediated transport	3.152714e-9
GO:0046903	secretion	1.006708e-8
GO:0001919	regulation of receptor recycling	2.467932e-8
GO:0006826	iron ion transport	5.308011e-8
GO:0055114	oxidation-reduction process	7.966200e-8
GO:0050663	cytokine secretion	8.278757e-8
GO:0046452	dihydrofolate metabolic process	8.445579e-8
GO:0042133	neurotransmitter metabolic process	1.612235e-7
GO:0006568	tryptophan metabolic process	1.819525e-7
GO:0042761	very long-chain fatty acid biosynthetic process	6.616982e-7
GO:0043570	maintenance of DNA repeat elements	8.370318e-7
GO:0030497	fatty acid elongation	9.201378e-7
GO:0097022	lymphocyte migration into lymph node	9.453009e-7
GO:0072610	interleukin-12 secretion	9.453009e-7
GO:0001555	oocyte growth	9.453009e-7
GO:0032615	interleukin-12 production	1.244584e-6
GO:0042359	vitamin D metabolic process	1.314106e-6
GO:0097026	dendritic cell dendrite assembly	1.400250e-6
GO:0006892	post-Golgi vesicle-mediated transport	1.512912e-6
GO:0000710	meiotic mismatch repair	1.645341e-6
GO:0021539	subthalamus development	1.726888e-6
GO:0007589	body fluid secretion	1.779370e-6
GO:0035721	intraflagellar retrograde transport	2.195283e-6
GO:0008202	steroid metabolic process	2.526460e-6
GO:0043001	Golgi to plasma membrane protein transport	3.544523e-6
GO:0010817	regulation of hormone levels	5.063105e-6
GO:0031295	T cell costimulation	5.227497e-6
GO:0002885	positive regulation of hypersensitivity	5.767571e-6
GO:0019441	tryptophan catabolic process to kynurenine	6.299013e-6
GO:0050764	regulation of phagocytosis	6.476283e-6
GO:0010738	regulation of protein kinase A signaling cascade	6.658878e-6
GO:0051704	multi-organism process	6.908090e-6
GO:0002076	osteoblast development	7.217613e-6
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	9.012389e-6
GO:2000647	negative regulation of stem cell proliferation	9.343040e-6
GO:0070563	negative regulation of vitamin D receptor signaling pathway	9.343040e-6
GO:0010839	negative regulation of keratinocyte proliferation	9.343040e-6
GO:0035921	desmosome disassembly	9.343040e-6
GO:2000412	positive regulation of thymocyte migration	9.966718e-6
GO:0002518	lymphocyte chemotaxis across high endothelial venule	9.966718e-6
GO:0070076	histone lysine demethylation	1.010913e-5
GO:0019432	triglyceride biosynthetic process	1.025064e-5
GO:0009108	coenzyme biosynthetic process	1.175910e-5
GO:0034115	negative regulation of heterotypic cell-cell adhesion	1.392440e-5
GO:0043526	neuroprotection	1.440062e-5
GO:0001505	regulation of neurotransmitter levels	1.542413e-5
GO:0001887	selenium compound metabolic process	1.709987e-5
GO:0002690	positive regulation of leukocyte chemotaxis	1.712537e-5
GO:0006893	Golgi to plasma membrane transport	1.760886e-5
GO:0015701	bicarbonate transport	1.762377e-5
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	1.862572e-5
GO:2000534	positive regulation of renal albumin absorption	1.862572e-5
GO:2000461	negative regulation of eukaryotic cell surface binding	1.862572e-5
GO:0070994	detection of oxidative stress	1.862572e-5
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	1.862572e-5
GO:0033169	histone H3-K9 demethylation	1.921165e-5
GO:0055072	iron ion homeostasis	2.065539e-5
GO:0061198	fungiform papilla formation	2.110820e-5
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.167104e-5
GO:0043112	receptor metabolic process	2.240794e-5
GO:0002687	positive regulation of leukocyte migration	2.451557e-5
GO:0061196	fungiform papilla development	2.594727e-5
GO:0018904	organic ether metabolic process	2.668474e-5
GO:0071731	response to nitric oxide	2.743834e-5
GO:0032940	secretion by cell	2.791774e-5
GO:0018963	phthalate metabolic process	2.862233e-5
GO:0019363	pyridine nucleotide biosynthetic process	2.994474e-5
GO:0045872	positive regulation of rhodopsin gene expression	3.093479e-5
GO:0006879	cellular iron ion homeostasis	3.166493e-5
GO:0046654	tetrahydrofolate biosynthetic process	3.253099e-5
GO:0001771	immunological synapse formation	3.571016e-5
GO:0070189	kynurenine metabolic process	3.750268e-5
GO:0006620	posttranslational protein targeting to membrane	3.750268e-5
GO:0010269	response to selenium ion	4.100522e-5
GO:0045056	transcytosis	4.277529e-5
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	4.303401e-5
GO:0009310	amine catabolic process	4.395932e-5
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4.590220e-5
GO:0021854	hypothalamus development	4.632535e-5
GO:0006706	steroid catabolic process	4.719593e-5
GO:0051707	response to other organism	4.851553e-5
GO:0001960	negative regulation of cytokine-mediated signaling pathway	5.065523e-5
GO:2000278	regulation of DNA biosynthetic process	5.105046e-5
GO:0032802	low-density lipoprotein particle receptor catabolic process	5.705032e-5
GO:0010743	regulation of macrophage derived foam cell differentiation	5.772593e-5
GO:0018879	biphenyl metabolic process	6.262245e-5
GO:0021860	pyramidal neuron development	6.262245e-5
GO:0002922	positive regulation of humoral immune response	6.346957e-5
GO:0002883	regulation of hypersensitivity	6.845874e-5
GO:0031427	response to methotrexate	7.239381e-5
GO:0002407	dendritic cell chemotaxis	8.335772e-5
GO:0071258	cellular response to gravity	8.383104e-5
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	8.383104e-5
GO:0061044	negative regulation of vascular wound healing	8.383104e-5
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	8.383104e-5
GO:0071622	regulation of granulocyte chemotaxis	8.575671e-5
GO:0030155	regulation of cell adhesion	8.664149e-5
GO:0010470	regulation of gastrulation	9.959881e-5
GO:0033034	positive regulation of myeloid cell apoptosis	1.068973e-4
GO:0001816	cytokine production	1.073037e-4
GO:0006810	transport	1.097581e-4
GO:0060789	hair follicle placode formation	1.104653e-4
GO:0051179	localization	1.130059e-4
GO:0018894	dibenzo-p-dioxin metabolic process	1.134005e-4
GO:0031623	receptor internalization	1.155117e-4
GO:0015705	iodide transport	1.163388e-4
GO:0010963	regulation of L-arginine import	1.163388e-4
GO:0015684	ferrous iron transport	1.163388e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.219493e-4
GO:0002688	regulation of leukocyte chemotaxis	1.221007e-4
GO:0051096	positive regulation of helicase activity	1.224070e-4
GO:0060706	cell differentiation involved in embryonic placenta development	1.278779e-4
GO:0042073	intraflagellar transport	1.356415e-4
GO:0048260	positive regulation of receptor-mediated endocytosis	1.371736e-4
GO:0050808	synapse organization	1.401945e-4
GO:0010632	regulation of epithelial cell migration	1.416499e-4
GO:0071377	cellular response to glucagon stimulus	1.602156e-4
GO:0002675	positive regulation of acute inflammatory response	1.660888e-4
GO:0021766	hippocampus development	1.703141e-4
GO:0006952	defense response	1.705507e-4
GO:0006586	indolalkylamine metabolic process	1.757127e-4
GO:0032423	regulation of mismatch repair	1.761256e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	1.763223e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	1.763223e-4
GO:0071637	regulation of monocyte chemotactic protein-1 production	1.797946e-4
GO:0030879	mammary gland development	1.836892e-4
GO:0016577	histone demethylation	2.150238e-4
GO:0042446	hormone biosynthetic process	2.171471e-4
GO:0046463	acylglycerol biosynthetic process	2.193499e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	2.366802e-4
GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	2.400724e-4
GO:0051095	regulation of helicase activity	2.460299e-4
GO:0009635	response to herbicide	2.465247e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.555779e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	2.582489e-4
GO:0070236	negative regulation of activation-induced cell death of T cells	2.582489e-4
GO:0070970	interleukin-2 secretion	2.582489e-4
GO:0070988	demethylation	2.700291e-4
GO:0032757	positive regulation of interleukin-8 production	2.908060e-4
GO:0033762	response to glucagon stimulus	2.968717e-4
GO:0051270	regulation of cellular component movement	3.065959e-4
GO:0051234	establishment of localization	3.126319e-4
GO:0010869	regulation of receptor biosynthetic process	3.195955e-4
GO:0030194	positive regulation of blood coagulation	3.204619e-4
GO:0021993	initiation of neural tube closure	3.246773e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	3.383117e-4
GO:0009988	cell-cell recognition	3.504363e-4
GO:0006482	protein demethylation	3.717263e-4
GO:0009098	leucine biosynthetic process	3.824074e-4
GO:0030327	prenylated protein catabolic process	3.824074e-4
GO:0006550	isoleucine catabolic process	3.824074e-4
GO:0021784	postganglionic parasympathetic nervous system development	3.843851e-4
GO:0001768	establishment of T cell polarity	4.059480e-4
GO:0006694	steroid biosynthetic process	4.110414e-4
GO:0045060	negative thymic T cell selection	4.173018e-4
GO:0006775	fat-soluble vitamin metabolic process	4.173018e-4
GO:0019674	NAD metabolic process	4.361082e-4
GO:0051918	negative regulation of fibrinolysis	4.385245e-4
GO:0045022	early endosome to late endosome transport	4.633845e-4
GO:0060384	innervation	4.663756e-4
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	4.749636e-4
GO:0045162	clustering of voltage-gated sodium channels	4.781629e-4
GO:0002685	regulation of leukocyte migration	4.825657e-4
GO:0051188	cofactor biosynthetic process	4.894471e-4
GO:0000050	urea cycle	5.155003e-4
GO:0030901	midbrain development	5.230739e-4
GO:0055089	fatty acid homeostasis	5.278641e-4
GO:2000145	regulation of cell motility	5.281254e-4
GO:0030111	regulation of Wnt receptor signaling pathway	5.369365e-4
GO:0006641	triglyceride metabolic process	5.406395e-4
GO:0035601	protein deacylation	5.435162e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	5.508780e-4
GO:0046504	glycerol ether biosynthetic process	5.618916e-4
GO:0010560	positive regulation of glycoprotein biosynthetic process	5.688714e-4
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	5.825796e-4
GO:0032101	regulation of response to external stimulus	5.915149e-4
GO:0007416	synapse assembly	5.962096e-4
GO:0034625	fatty acid elongation, monounsaturated fatty acid	5.977802e-4
GO:0002649	regulation of tolerance induction to self antigen	6.073687e-4
GO:0065008	regulation of biological quality	6.217149e-4
GO:0051262	protein tetramerization	6.236192e-4
GO:0048513	organ development	6.397313e-4
GO:0030100	regulation of endocytosis	6.567467e-4
GO:0007275	multicellular organismal development	6.638663e-4
GO:0009072	aromatic amino acid family metabolic process	6.836540e-4
GO:0021592	fourth ventricle development	6.962610e-4
GO:0090023	positive regulation of neutrophil chemotaxis	7.238698e-4
GO:0006766	vitamin metabolic process	7.355654e-4
GO:0050766	positive regulation of phagocytosis	7.394703e-4
GO:0055091	phospholipid homeostasis	7.400635e-4
GO:0060788	ectodermal placode formation	7.410107e-4
GO:0010758	regulation of macrophage chemotaxis	7.494309e-4
GO:2000279	negative regulation of DNA biosynthetic process	7.572775e-4
GO:0001522	pseudouridine synthesis	7.573393e-4
GO:0006344	maintenance of chromatin silencing	7.609622e-4
GO:0070571	negative regulation of neuron projection regeneration	7.609622e-4
GO:0060627	regulation of vesicle-mediated transport	7.664653e-4
GO:0044242	cellular lipid catabolic process	7.768021e-4
GO:0022408	negative regulation of cell-cell adhesion	7.788988e-4
GO:0030540	female genitalia development	7.988028e-4
GO:0010519	negative regulation of phospholipase activity	8.059498e-4
GO:0009231	riboflavin biosynthetic process	8.059498e-4
GO:0006545	glycine biosynthetic process	8.059498e-4
GO:0034694	response to prostaglandin stimulus	8.222880e-4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	8.222880e-4
GO:0048692	negative regulation of axon extension involved in regeneration	8.472270e-4
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	8.536359e-4
GO:0006476	protein deacetylation	8.711913e-4
GO:0030916	otic vesicle formation	8.760884e-4
GO:0007162	negative regulation of cell adhesion	8.809394e-4
GO:0043367	CD4-positive, alpha-beta T cell differentiation	8.891749e-4
GO:0010745	negative regulation of macrophage derived foam cell differentiation	9.054147e-4
GO:0009607	response to biotic stimulus	9.132528e-4
GO:0042110	T cell activation	9.168054e-4
GO:0009100	glycoprotein metabolic process	9.175942e-4
GO:0030217	T cell differentiation	9.311780e-4
GO:0006885	regulation of pH	9.406881e-4
GO:0032703	negative regulation of interleukin-2 production	9.467442e-4
GO:0032102	negative regulation of response to external stimulus	9.530661e-4
GO:0021761	limbic system development	9.532684e-4
GO:2000401	regulation of lymphocyte migration	9.549537e-4
GO:0030334	regulation of cell migration	1.000687e-3
GO:0006639	acylglycerol metabolic process	1.002064e-3
GO:0050921	positive regulation of chemotaxis	1.018152e-3
GO:0042727	flavin-containing compound biosynthetic process	1.024404e-3
GO:0061043	regulation of vascular wound healing	1.024404e-3
GO:0050773	regulation of dendrite development	1.029093e-3
GO:0042541	hemoglobin biosynthetic process	1.032327e-3
GO:0061045	negative regulation of wound healing	1.042536e-3
GO:0048681	negative regulation of axon regeneration	1.042536e-3
GO:0046174	polyol catabolic process	1.042536e-3
GO:0051160	L-xylitol catabolic process	1.045227e-3
GO:0006062	sorbitol catabolic process	1.045227e-3
GO:0046370	fructose biosynthetic process	1.045227e-3
GO:0030073	insulin secretion	1.055925e-3
GO:0006576	cellular biogenic amine metabolic process	1.084416e-3
GO:0072298	regulation of metanephric glomerulus development	1.086569e-3
GO:0043604	amide biosynthetic process	1.086569e-3
GO:0031953	negative regulation of protein autophosphorylation	1.121743e-3
GO:0045995	regulation of embryonic development	1.126961e-3
GO:0060041	retina development in camera-type eye	1.178829e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	1.185085e-3
GO:0043374	CD8-positive, alpha-beta T cell differentiation	1.185129e-3
GO:0006429	leucyl-tRNA aminoacylation	1.186514e-3
GO:0010870	positive regulation of receptor biosynthetic process	1.189490e-3
GO:0010759	positive regulation of macrophage chemotaxis	1.194067e-3
GO:0010886	positive regulation of cholesterol storage	1.211078e-3
GO:0090287	regulation of cellular response to growth factor stimulus	1.227181e-3
GO:0010890	positive regulation of sequestering of triglyceride	1.241630e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	1.263856e-3
GO:0048193	Golgi vesicle transport	1.266402e-3
GO:0050873	brown fat cell differentiation	1.279417e-3
GO:0043984	histone H4-K16 acetylation	1.283878e-3
GO:0021591	ventricular system development	1.290830e-3
GO:0006082	organic acid metabolic process	1.291571e-3
GO:0046632	alpha-beta T cell differentiation	1.295256e-3
GO:0042180	cellular ketone metabolic process	1.311768e-3
GO:0002456	T cell mediated immunity	1.314292e-3
GO:0045806	negative regulation of endocytosis	1.327425e-3
GO:0050900	leukocyte migration	1.333549e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.367982e-3
GO:0060572	morphogenesis of an epithelial bud	1.379664e-3
GO:0021548	pons development	1.404196e-3
GO:0051917	regulation of fibrinolysis	1.405773e-3
GO:0040012	regulation of locomotion	1.408739e-3
GO:0007565	female pregnancy	1.411786e-3
GO:0006702	androgen biosynthetic process	1.414605e-3
GO:0002252	immune effector process	1.468465e-3
GO:0002548	monocyte chemotaxis	1.468518e-3
GO:0001922	B-1 B cell homeostasis	1.481083e-3
GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.482287e-3
GO:0006898	receptor-mediated endocytosis	1.551923e-3
GO:2000114	regulation of establishment of cell polarity	1.566709e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.588813e-3
GO:0010957	negative regulation of vitamin D biosynthetic process	1.588813e-3
GO:0001300	chronological cell aging	1.588813e-3
GO:0006551	leucine metabolic process	1.588813e-3
GO:0034695	response to prostaglandin E stimulus	1.595531e-3
GO:0046888	negative regulation of hormone secretion	1.602511e-3
GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	1.610617e-3
GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion	1.610617e-3
GO:0008615	pyridoxine biosynthetic process	1.610617e-3
GO:0016044	cellular membrane organization	1.625886e-3
GO:0045047	protein targeting to ER	1.645612e-3
GO:0060437	lung growth	1.652482e-3
GO:0019227	neuronal action potential propagation	1.652482e-3
GO:2000147	positive regulation of cell motility	1.664079e-3
GO:0030335	positive regulation of cell migration	1.673119e-3
GO:0033032	regulation of myeloid cell apoptosis	1.710308e-3
GO:0019752	carboxylic acid metabolic process	1.718735e-3
GO:0009306	protein secretion	1.730401e-3
GO:0008543	fibroblast growth factor receptor signaling pathway	1.735379e-3
GO:0050765	negative regulation of phagocytosis	1.744104e-3
GO:0061024	membrane organization	1.745334e-3
GO:0006662	glycerol ether metabolic process	1.766051e-3
GO:0048855	adenohypophysis morphogenesis	1.776672e-3
GO:0032383	regulation of intracellular cholesterol transport	1.776672e-3
GO:0045650	negative regulation of macrophage differentiation	1.787191e-3
GO:0016553	base conversion or substitution editing	1.787191e-3
GO:0044344	cellular response to fibroblast growth factor stimulus	1.821887e-3
GO:0042742	defense response to bacterium	1.845598e-3
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.872102e-3
GO:0050820	positive regulation of coagulation	1.899678e-3
GO:0070328	triglyceride homeostasis	1.930040e-3
GO:0006638	neutral lipid metabolic process	1.949877e-3
GO:0048259	regulation of receptor-mediated endocytosis	1.966143e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	2.015489e-3
GO:0003218	cardiac left ventricle formation	2.030993e-3
GO:0009074	aromatic amino acid family catabolic process	2.049541e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	2.049541e-3
GO:0016998	cell wall macromolecule catabolic process	2.067740e-3
GO:0016042	lipid catabolic process	2.072781e-3
GO:0046631	alpha-beta T cell activation	2.094954e-3
GO:0006732	coenzyme metabolic process	2.119483e-3
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	2.129617e-3
GO:0060409	positive regulation of acetylcholine metabolic process	2.129617e-3
GO:0032765	positive regulation of mast cell cytokine production	2.129617e-3
GO:0002431	Fc receptor mediated stimulatory signaling pathway	2.129617e-3
GO:0042574	retinal metabolic process	2.132835e-3
GO:0002090	regulation of receptor internalization	2.132835e-3
GO:0040017	positive regulation of locomotion	2.144513e-3
GO:0043383	negative T cell selection	2.161571e-3
GO:0071600	otic vesicle morphogenesis	2.227758e-3
GO:0009617	response to bacterium	2.266640e-3
GO:0006298	mismatch repair	2.268130e-3
GO:0048731	system development	2.281044e-3
GO:0045844	positive regulation of striated muscle tissue development	2.283284e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.293556e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	2.353277e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	2.353277e-3
GO:0071675	regulation of mononuclear cell migration	2.377999e-3
GO:0051272	positive regulation of cellular component movement	2.498306e-3
GO:0006897	endocytosis	2.529996e-3
GO:0070849	response to epidermal growth factor stimulus	2.537092e-3
GO:0000038	very long-chain fatty acid metabolic process	2.545806e-3
GO:0021678	third ventricle development	2.595035e-3
GO:0044248	cellular catabolic process	2.699865e-3
GO:0016554	cytidine to uridine editing	2.703720e-3
GO:0007498	mesoderm development	2.711944e-3
GO:0061181	regulation of chondrocyte development	2.822061e-3
GO:0043049	otic placode formation	2.822061e-3
GO:0046849	bone remodeling	2.923471e-3
GO:0009615	response to virus	3.058132e-3
GO:0032501	multicellular organismal process	3.099669e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	3.101024e-3
GO:0010885	regulation of cholesterol storage	3.107073e-3
GO:0019367	fatty acid elongation, saturated fatty acid	3.107377e-3
GO:0006629	lipid metabolic process	3.141900e-3
GO:0055067	monovalent inorganic cation homeostasis	3.212211e-3
GO:0090192	regulation of glomerulus development	3.258997e-3
GO:0010820	positive regulation of T cell chemotaxis	3.279556e-3
GO:0090022	regulation of neutrophil chemotaxis	3.339578e-3
GO:0046642	negative regulation of alpha-beta T cell proliferation	3.347799e-3
GO:0010716	negative regulation of extracellular matrix disassembly	3.354765e-3
GO:0016071	mRNA metabolic process	3.360482e-3
GO:0002437	inflammatory response to antigenic stimulus	3.375587e-3
GO:0055088	lipid homeostasis	3.441307e-3
GO:0008298	intracellular mRNA localization	3.491609e-3
GO:2000406	positive regulation of T cell migration	3.519649e-3
GO:0000003	reproduction	3.529042e-3
GO:0009611	response to wounding	3.558201e-3
GO:0051607	defense response to virus	3.580485e-3
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	3.645633e-3
GO:0048247	lymphocyte chemotaxis	3.645633e-3
GO:0072207	metanephric epithelium development	3.648033e-3
GO:0051220	cytoplasmic sequestering of protein	3.648767e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	3.731615e-3
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	3.839952e-3
GO:0050878	regulation of body fluid levels	3.891689e-3
GO:0070316	regulation of G0 to G1 transition	3.956056e-3
GO:0001757	somite specification	3.956056e-3
GO:0033629	negative regulation of cell adhesion mediated by integrin	3.956056e-3
GO:0070542	response to fatty acid	3.995126e-3
GO:0072659	protein localization in plasma membrane	4.041958e-3
GO:0042074	cell migration involved in gastrulation	4.041958e-3
GO:0032103	positive regulation of response to external stimulus	4.045203e-3
GO:0032680	regulation of tumor necrosis factor production	4.051451e-3
GO:0042439	ethanolamine-containing compound metabolic process	4.060140e-3
GO:0010739	positive regulation of protein kinase A signaling cascade	4.076237e-3
GO:0022407	regulation of cell-cell adhesion	4.237151e-3
GO:0031952	regulation of protein autophosphorylation	4.274001e-3
GO:0042666	negative regulation of ectodermal cell fate specification	4.332759e-3
GO:0050703	interleukin-1 alpha secretion	4.332759e-3
GO:0035417	negative regulation of mitotic prometaphase	4.332759e-3
GO:0006587	serotonin biosynthetic process from tryptophan	4.332759e-3
GO:0042823	pyridoxal phosphate biosynthetic process	4.353507e-3
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	4.400941e-3
GO:0009651	response to salt stress	4.402578e-3
GO:0003032	detection of oxygen	4.588956e-3
GO:0008380	RNA splicing	4.628879e-3
GO:0014032	neural crest cell development	4.637050e-3
GO:0070544	histone H3-K36 demethylation	4.665060e-3
GO:0060485	mesenchyme development	4.712628e-3
GO:0046496	nicotinamide nucleotide metabolic process	4.718891e-3
GO:0019433	triglyceride catabolic process	4.807753e-3
GO:0001707	mesoderm formation	4.866333e-3
GO:0045061	thymic T cell selection	4.903483e-3
GO:0043603	cellular amide metabolic process	4.920425e-3
GO:0007158	neuron cell-cell adhesion	4.920425e-3
GO:0072676	lymphocyte migration	4.939242e-3
GO:0010867	positive regulation of triglyceride biosynthetic process	5.182155e-3
GO:0050920	regulation of chemotaxis	5.199434e-3
GO:0048856	anatomical structure development	5.206080e-3
GO:0006958	complement activation, classical pathway	5.222935e-3
GO:0042060	wound healing	5.309371e-3
GO:0002832	negative regulation of response to biotic stimulus	5.314208e-3
GO:0070483	detection of hypoxia	5.347991e-3
GO:0071674	mononuclear cell migration	5.347991e-3
GO:0043950	positive regulation of cAMP-mediated signaling	5.347991e-3
GO:0003223	ventricular compact myocardium morphogenesis	5.347991e-3
GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	5.347991e-3
GO:0034112	positive regulation of homotypic cell-cell adhesion	5.347991e-3
GO:0010884	positive regulation of lipid storage	5.377634e-3
GO:0042445	hormone metabolic process	5.408134e-3
GO:0006895	Golgi to endosome transport	5.427445e-3
GO:0032677	regulation of interleukin-8 production	5.441298e-3
GO:0010715	regulation of extracellular matrix disassembly	5.459062e-3
GO:0006470	protein dephosphorylation	5.536009e-3
GO:0072657	protein localization in membrane	5.551542e-3
GO:0042098	T cell proliferation	5.562556e-3
GO:0097029	mature dendritic cell differentiation	5.584106e-3
GO:0015698	inorganic anion transport	5.655625e-3
GO:0048609	multicellular organismal reproductive process	5.673842e-3
GO:0071398	cellular response to fatty acid	5.788228e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	5.788228e-3
GO:0001704	formation of primary germ layer	5.808371e-3
GO:0006637	acyl-CoA metabolic process	5.860948e-3
GO:0009101	glycoprotein biosynthetic process	5.862923e-3
GO:0006820	anion transport	5.864479e-3
GO:0035066	positive regulation of histone acetylation	5.987215e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	6.037647e-3
GO:0034113	heterotypic cell-cell adhesion	6.046868e-3
GO:0003214	cardiac left ventricle morphogenesis	6.135590e-3
GO:0002643	regulation of tolerance induction	6.138977e-3
GO:0007494	midgut development	6.176928e-3
GO:0002790	peptide secretion	6.185516e-3
GO:0030072	peptide hormone secretion	6.211685e-3
GO:0002920	regulation of humoral immune response	6.323642e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	6.353618e-3
GO:0033197	response to vitamin E	6.372854e-3
GO:0006486	protein glycosylation	6.409600e-3
GO:0032799	low-density lipoprotein receptor particle metabolic process	6.483501e-3
GO:0061364	apoptosis involved in luteolysis	6.483501e-3
GO:0045453	bone resorption	6.678838e-3
GO:0070085	glycosylation	6.729371e-3
GO:0009914	hormone transport	6.734586e-3
GO:0060401	cytosolic calcium ion transport	6.735219e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	6.761352e-3
GO:0010744	positive regulation of macrophage derived foam cell differentiation	6.832329e-3
GO:0030323	respiratory tube development	6.840941e-3
GO:0033211	adiponectin-mediated signaling pathway	6.841080e-3
GO:0044281	small molecule metabolic process	6.847514e-3
GO:0046640	regulation of alpha-beta T cell proliferation	6.860994e-3
GO:0001910	regulation of leukocyte mediated cytotoxicity	6.864818e-3
GO:0002287	alpha-beta T cell activation involved in immune response	6.879656e-3
GO:0043434	response to peptide hormone stimulus	6.991498e-3
GO:0072234	metanephric nephron tubule development	7.090181e-3
GO:0006269	DNA replication, synthesis of RNA primer	7.139079e-3
GO:0080135	regulation of cellular response to stress	7.233862e-3
GO:0048286	lung alveolus development	7.253370e-3
GO:0030324	lung development	7.282106e-3
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	7.298293e-3
GO:0050829	defense response to Gram-negative bacterium	7.389077e-3
GO:0035067	negative regulation of histone acetylation	7.389077e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	7.394139e-3
GO:0072170	metanephric tubule development	7.427611e-3
GO:0048332	mesoderm morphogenesis	7.435546e-3
GO:0002017	regulation of blood volume by renal aldosterone	7.459679e-3
GO:0050729	positive regulation of inflammatory response	7.589577e-3
GO:0019835	cytolysis	7.742219e-3
GO:0046464	acylglycerol catabolic process	7.757698e-3
GO:0001913	T cell mediated cytotoxicity	7.767994e-3
GO:0034766	negative regulation of ion transmembrane transport	7.767994e-3
GO:0022414	reproductive process	7.873703e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.888538e-3
GO:0043302	positive regulation of leukocyte degranulation	7.901390e-3
GO:0032502	developmental process	7.942201e-3
GO:0014033	neural crest cell differentiation	7.948150e-3
GO:0015672	monovalent inorganic cation transport	8.030099e-3
GO:0051053	negative regulation of DNA metabolic process	8.097622e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	8.126893e-3
GO:0090381	regulation of heart induction	8.151680e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	8.151680e-3
GO:0034754	cellular hormone metabolic process	8.370074e-3
GO:0035065	regulation of histone acetylation	8.374791e-3
GO:0070317	negative regulation of G0 to G1 transition	8.443903e-3
GO:0022615	protein to membrane docking	8.443903e-3
GO:0002223	stimulatory C-type lectin receptor signaling pathway	8.443903e-3
GO:0001782	B cell homeostasis	8.549170e-3
GO:2000107	negative regulation of leukocyte apoptosis	8.694854e-3