Novel motif:42

name:	motif42_CGNTCA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006481	C-terminal protein methylation	7.998625e-10
GO:0031929	TOR signaling cascade	8.343789e-8
GO:0051313	attachment of spindle microtubules to chromosome	9.489041e-8
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.125278e-7
GO:0006369	termination of RNA polymerase II transcription	1.250812e-7
GO:0010836	negative regulation of protein ADP-ribosylation	3.119637e-7
GO:0042149	cellular response to glucose starvation	3.932530e-7
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	8.014499e-7
GO:0000387	spliceosomal snRNP assembly	1.293966e-6
GO:0043503	skeletal muscle fiber adaptation	1.339861e-6
GO:0007021	tubulin complex assembly	1.610496e-6
GO:0072668	tubulin complex biogenesis	2.176417e-6
GO:0060017	parathyroid gland development	4.931050e-6
GO:0010625	positive regulation of Schwann cell proliferation	5.665798e-6
GO:0000296	spermine transport	5.683164e-6
GO:0031468	nuclear envelope reassembly	5.691087e-6
GO:0072268	pattern specification involved in metanephros development	6.680332e-6
GO:0006534	cysteine metabolic process	6.937638e-6
GO:0006364	rRNA processing	7.465565e-6
GO:0002769	natural killer cell inhibitory signaling pathway	7.997172e-6
GO:0032926	negative regulation of activin receptor signaling pathway	9.682684e-6
GO:0016072	rRNA metabolic process	9.824884e-6
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	1.242270e-5
GO:0006600	creatine metabolic process	1.851806e-5
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1.897100e-5
GO:0001805	positive regulation of type III hypersensitivity	1.897100e-5
GO:0097029	mature dendritic cell differentiation	2.139660e-5
GO:0060977	coronary vasculature morphogenesis	2.162981e-5
GO:0042503	tyrosine phosphorylation of Stat3 protein	2.317316e-5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2.369773e-5
GO:0032769	negative regulation of monooxygenase activity	2.712241e-5
GO:0002861	regulation of inflammatory response to antigenic stimulus	3.138533e-5
GO:0002036	regulation of L-glutamate transport	3.206625e-5
GO:0044140	negative regulation of growth of symbiont on or near host surface	3.296437e-5
GO:0000414	regulation of histone H3-K36 methylation	3.792895e-5
GO:0010624	regulation of Schwann cell proliferation	3.890670e-5
GO:0061015	snRNA import into nucleus	3.982039e-5
GO:0006868	glutamine transport	5.059592e-5
GO:0046813	virion attachment, binding of host cell surface receptor	6.280461e-5
GO:0008054	cyclin catabolic process	6.860684e-5
GO:0071421	manganese ion transmembrane transport	7.165429e-5
GO:0000389	nuclear mRNA 3'-splice site recognition	7.165429e-5
GO:0006447	regulation of translational initiation by iron	7.546016e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	7.885125e-5
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	8.280190e-5
GO:0009070	serine family amino acid biosynthetic process	9.009246e-5
GO:0043088	regulation of Cdc42 GTPase activity	9.011434e-5
GO:0042506	tyrosine phosphorylation of Stat5 protein	9.346772e-5
GO:0014829	vascular smooth muscle contraction	9.687208e-5
GO:0070544	histone H3-K36 demethylation	9.750702e-5
GO:0043587	tongue morphogenesis	1.017182e-4
GO:0003218	cardiac left ventricle formation	1.039717e-4
GO:0060695	negative regulation of cholesterol transporter activity	1.098996e-4
GO:0070194	synaptonemal complex disassembly	1.166189e-4
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.166189e-4
GO:0008608	attachment of spindle microtubules to kinetochore	1.210474e-4
GO:0019344	cysteine biosynthetic process	1.211706e-4
GO:0009069	serine family amino acid metabolic process	1.268907e-4
GO:0006432	phenylalanyl-tRNA aminoacylation	1.274827e-4
GO:0021658	rhombomere 3 morphogenesis	1.397101e-4
GO:0014740	negative regulation of muscle hyperplasia	1.542898e-4
GO:0014888	striated muscle adaptation	1.569407e-4
GO:0007422	peripheral nervous system development	1.584031e-4
GO:0001710	mesodermal cell fate commitment	1.598154e-4
GO:0051764	actin crosslink formation	1.653489e-4
GO:0060356	leucine import	1.774854e-4
GO:0030644	cellular chloride ion homeostasis	1.775892e-4
GO:0003329	pancreatic PP cell fate commitment	1.808802e-4
GO:0003326	pancreatic A cell fate commitment	1.808802e-4
GO:0070814	hydrogen sulfide biosynthetic process	1.935285e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.953373e-4
GO:0016340	calcium-dependent cell-matrix adhesion	2.040726e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	2.088568e-4
GO:0048280	vesicle fusion with Golgi apparatus	2.097897e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.258101e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	2.296836e-4
GO:0021895	cerebral cortex neuron differentiation	2.416787e-4
GO:0072179	nephric duct formation	2.452633e-4
GO:0043501	skeletal muscle adaptation	2.458098e-4
GO:0043491	protein kinase B signaling cascade	2.576128e-4
GO:0033342	negative regulation of collagen binding	2.622091e-4
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	2.622091e-4
GO:0009589	detection of UV	2.622091e-4
GO:0003148	outflow tract septum morphogenesis	2.667608e-4
GO:0008380	RNA splicing	2.689319e-4
GO:0040040	thermosensory behavior	2.722947e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	2.722947e-4
GO:0051299	centrosome separation	3.084191e-4
GO:0050685	positive regulation of mRNA processing	3.125728e-4
GO:0022038	corpus callosum development	3.316074e-4
GO:0050667	homocysteine metabolic process	3.370696e-4
GO:0051457	maintenance of protein location in nucleus	3.713470e-4
GO:0072176	nephric duct development	3.737686e-4
GO:0060252	positive regulation of glial cell proliferation	3.913361e-4
GO:0072178	nephric duct morphogenesis	4.204488e-4
GO:0046796	viral genome transport in host cell	4.257581e-4
GO:0051205	protein insertion into membrane	4.466020e-4
GO:0051955	regulation of amino acid transport	4.551356e-4
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	4.632164e-4
GO:0030277	maintenance of gastrointestinal epithelium	4.709759e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	4.746038e-4
GO:0000375	RNA splicing, via transesterification reactions	4.852674e-4
GO:0001812	positive regulation of type I hypersensitivity	4.874073e-4
GO:0002885	positive regulation of hypersensitivity	4.882229e-4
GO:2000195	negative regulation of female gonad development	4.936341e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	5.396603e-4
GO:0014002	astrocyte development	5.547211e-4
GO:0070141	response to UV-A	5.675822e-4
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	5.743175e-4
GO:2000194	regulation of female gonad development	6.081873e-4
GO:0042254	ribosome biogenesis	6.168216e-4
GO:0035767	endothelial cell chemotaxis	6.208611e-4
GO:0043418	homocysteine catabolic process	6.379034e-4
GO:0061157	mRNA destabilization	6.379034e-4
GO:0019346	transsulfuration	6.379034e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	6.379034e-4
GO:0006478	peptidyl-tyrosine sulfation	6.379034e-4
GO:0006535	cysteine biosynthetic process from serine	6.379034e-4
GO:0019343	cysteine biosynthetic process via cystathionine	6.379034e-4
GO:0034214	protein hexamerization	6.379504e-4
GO:2001037	positive regulation of tongue muscle cell differentiation	6.402081e-4
GO:0097152	mesenchymal cell apoptosis	6.402081e-4
GO:0060982	coronary artery morphogenesis	6.402081e-4
GO:0006844	acyl carnitine transport	6.618881e-4
GO:0008334	histone mRNA metabolic process	6.647063e-4
GO:0060620	regulation of cholesterol import	6.826938e-4
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.617982e-4
GO:0021869	forebrain ventricular zone progenitor cell division	7.709481e-4
GO:0002037	negative regulation of L-glutamate transport	7.724054e-4
GO:0045994	positive regulation of translational initiation by iron	7.724054e-4
GO:0021954	central nervous system neuron development	7.747934e-4
GO:0000415	negative regulation of histone H3-K36 methylation	8.474882e-4
GO:0048203	vesicle targeting, trans-Golgi to endosome	8.560100e-4
GO:0031023	microtubule organizing center organization	9.016996e-4
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	9.089352e-4
GO:0007198	inhibition of adenylate cyclase activity by serotonin receptor signaling pathway	9.398048e-4
GO:0015761	mannose transport	9.398048e-4
GO:0006425	glutaminyl-tRNA aminoacylation	9.398048e-4
GO:0060534	trachea cartilage development	9.474918e-4
GO:0042508	tyrosine phosphorylation of Stat1 protein	9.688493e-4
GO:0070574	cadmium ion transmembrane transport	9.707680e-4
GO:0022613	ribonucleoprotein complex biogenesis	9.769768e-4
GO:0021528	commissural neuron differentiation in spinal cord	9.885217e-4
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	9.885217e-4
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	9.885217e-4
GO:0051956	negative regulation of amino acid transport	1.034135e-3
GO:0046500	S-adenosylmethionine metabolic process	1.046085e-3
GO:0035883	enteroendocrine cell differentiation	1.075395e-3
GO:0048790	maintenance of presynaptic active zone structure	1.091874e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.091874e-3
GO:0006379	mRNA cleavage	1.112634e-3
GO:0019264	glycine biosynthetic process from serine	1.113347e-3
GO:0000917	barrier septum formation	1.140343e-3
GO:0060020	Bergmann glial cell differentiation	1.175422e-3
GO:0051572	negative regulation of histone H3-K4 methylation	1.207469e-3
GO:0006626	protein targeting to mitochondrion	1.210529e-3
GO:0014738	regulation of muscle hyperplasia	1.214318e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	1.271767e-3
GO:0006635	fatty acid beta-oxidation	1.274011e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.279696e-3
GO:0006853	carnitine shuttle	1.281065e-3
GO:0006984	ER-nucleus signaling pathway	1.288719e-3
GO:0034660	ncRNA metabolic process	1.341469e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.368210e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.374723e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.379028e-3
GO:0006545	glycine biosynthetic process	1.417112e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	1.446109e-3
GO:0022007	convergent extension involved in neural plate elongation	1.476350e-3
GO:0006423	cysteinyl-tRNA aminoacylation	1.506608e-3
GO:0014037	Schwann cell differentiation	1.577073e-3
GO:0006656	phosphatidylcholine biosynthetic process	1.609438e-3
GO:0072655	establishment of protein localization in mitochondrion	1.611345e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.655448e-3
GO:0001798	positive regulation of type IIa hypersensitivity	1.679172e-3
GO:0006657	CDP-choline pathway	1.679707e-3
GO:0070407	oxidation-dependent protein catabolic process	1.683261e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	1.724978e-3
GO:0051297	centrosome organization	1.735828e-3
GO:0032526	response to retinoic acid	1.738568e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	1.757603e-3
GO:0051354	negative regulation of oxidoreductase activity	1.896291e-3
GO:0035305	negative regulation of dephosphorylation	1.990619e-3
GO:0061101	neuroendocrine cell differentiation	2.005748e-3
GO:0000185	activation of MAPKKK activity	2.017923e-3
GO:0016598	protein arginylation	2.040998e-3
GO:0035966	response to topologically incorrect protein	2.048233e-3
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.220741e-3
GO:0070585	protein localization in mitochondrion	2.230471e-3
GO:0031442	positive regulation of mRNA 3'-end processing	2.246759e-3
GO:0045007	depurination	2.258033e-3
GO:0032365	intracellular lipid transport	2.259824e-3
GO:0060659	nipple sheath formation	2.260973e-3
GO:0060649	mammary gland bud elongation	2.260973e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	2.265487e-3
GO:0071318	cellular response to ATP	2.316361e-3
GO:0060621	negative regulation of cholesterol import	2.332510e-3
GO:0006398	histone mRNA 3'-end processing	2.332510e-3
GO:0007141	male meiosis I	2.452921e-3
GO:0045835	negative regulation of meiosis	2.452921e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	2.492747e-3
GO:0034384	high-density lipoprotein particle clearance	2.531108e-3
GO:0019448	L-cysteine catabolic process	2.658220e-3
GO:0050689	negative regulation of defense response to virus by host	2.658220e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	2.670222e-3
GO:0090083	regulation of inclusion body assembly	2.731066e-3
GO:0000089	mitotic metaphase	2.731066e-3
GO:0006285	base-excision repair, AP site formation	2.756802e-3
GO:0051793	medium-chain fatty acid catabolic process	2.800974e-3
GO:0042780	tRNA 3'-end processing	2.800974e-3
GO:0023035	CD40 signaling pathway	2.800974e-3
GO:0019062	virion attachment to host cell surface receptor	2.833530e-3
GO:0014745	negative regulation of muscle adaptation	2.834897e-3
GO:0046939	nucleotide phosphorylation	3.002666e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	3.069730e-3
GO:0021985	neurohypophysis development	3.069730e-3
GO:0019478	D-amino acid catabolic process	3.070815e-3
GO:0002438	acute inflammatory response to antigenic stimulus	3.070815e-3
GO:0032202	telomere assembly	3.188533e-3
GO:0090086	negative regulation of protein deubiquitination	3.286184e-3
GO:0001958	endochondral ossification	3.342188e-3
GO:0006760	folic acid-containing compound metabolic process	3.347199e-3
GO:0032099	negative regulation of appetite	3.356602e-3
GO:0016197	endosome transport	3.383108e-3
GO:0071843	cellular component biogenesis at cellular level	3.387245e-3
GO:0021666	rhombomere 5 formation	3.444092e-3
GO:0021660	rhombomere 3 formation	3.444092e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	3.447916e-3
GO:0046655	folic acid metabolic process	3.479070e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	3.498523e-3
GO:0030073	insulin secretion	3.538190e-3
GO:0060976	coronary vasculature development	3.631848e-3
GO:0006457	protein folding	3.634346e-3
GO:0071584	negative regulation of zinc ion import	3.674908e-3
GO:0090281	negative regulation of calcium ion import	3.674908e-3
GO:0051791	medium-chain fatty acid metabolic process	3.674908e-3
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	3.674908e-3
GO:0032915	positive regulation of transforming growth factor beta2 production	3.674908e-3
GO:0000073	spindle pole body separation	3.674908e-3
GO:0000072	M phase specific microtubule process	3.686237e-3
GO:0002149	hypochlorous acid biosynthetic process	3.706853e-3
GO:0032096	negative regulation of response to food	3.757154e-3
GO:0042558	pteridine-containing compound metabolic process	3.758066e-3
GO:0034470	ncRNA processing	3.777042e-3
GO:0046856	phosphatidylinositol dephosphorylation	3.809457e-3
GO:0002679	respiratory burst involved in defense response	3.850741e-3
GO:0000236	mitotic prometaphase	3.877185e-3
GO:0043951	negative regulation of cAMP-mediated signaling	3.959093e-3
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	3.966046e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.009327e-3
GO:0061084	negative regulation of protein refolding	4.012320e-3
GO:0001974	blood vessel remodeling	4.120758e-3
GO:0007260	tyrosine phosphorylation of STAT protein	4.121220e-3
GO:0019086	late viral mRNA transcription	4.165000e-3
GO:0034453	microtubule anchoring	4.198113e-3
GO:0051546	keratinocyte migration	4.315321e-3
GO:0051684	maintenance of Golgi location	4.404528e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.404528e-3
GO:0007029	endoplasmic reticulum organization	4.431562e-3
GO:0055025	positive regulation of cardiac muscle tissue development	4.433286e-3
GO:0007500	mesodermal cell fate determination	4.449302e-3
GO:2000667	positive regulation of interleukin-13 secretion	4.565187e-3
GO:2000665	regulation of interleukin-13 secretion	4.565187e-3
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	4.565187e-3
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	4.565187e-3
GO:2000664	positive regulation of interleukin-5 secretion	4.565187e-3
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	4.565187e-3
GO:2000662	regulation of interleukin-5 secretion	4.565187e-3
GO:0071276	cellular response to cadmium ion	4.566371e-3
GO:0035441	cell migration involved in vasculogenesis	4.607649e-3
GO:0070171	negative regulation of tooth mineralization	4.656821e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	4.656821e-3
GO:0061103	carotid body glomus cell differentiation	4.657798e-3
GO:0061104	adrenal chromaffin cell differentiation	4.657798e-3
GO:0071259	cellular response to magnetism	4.657798e-3
GO:0061102	stomach neuroendocrine cell differentiation	4.657798e-3
GO:0003359	noradrenergic neuron fate commitment	4.657798e-3
GO:0061100	lung neuroendocrine cell differentiation	4.657798e-3
GO:0060163	subpallium neuron fate commitment	4.657798e-3
GO:0007400	neuroblast fate determination	4.657798e-3
GO:0060165	regulation of timing of subpallium neuron differentiation	4.657798e-3
GO:0021592	fourth ventricle development	4.716736e-3
GO:0072595	maintenance of protein localization to organelle	4.778372e-3
GO:0006839	mitochondrial transport	4.829065e-3
GO:0034505	tooth mineralization	5.086353e-3
GO:0007000	nucleolus organization	5.184415e-3
GO:0046778	modification by virus of host mRNA processing	5.184415e-3
GO:0051642	centrosome localization	5.209748e-3
GO:0006986	response to unfolded protein	5.278498e-3
GO:0002883	regulation of hypersensitivity	5.388822e-3
GO:0034380	high-density lipoprotein particle assembly	5.388822e-3
GO:0018208	peptidyl-proline modification	5.404925e-3
GO:0051953	negative regulation of amine transport	5.448279e-3
GO:0006348	chromatin silencing at telomere	5.491869e-3
GO:0002765	immune response-inhibiting signal transduction	5.491869e-3
GO:0048050	post-embryonic eye morphogenesis	5.703485e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	5.703485e-3
GO:0061004	pattern specification involved in kidney development	5.755416e-3
GO:0090085	regulation of protein deubiquitination	5.792708e-3
GO:0001732	formation of translation initiation complex	5.937668e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	5.964558e-3
GO:0060350	endochondral bone morphogenesis	5.973655e-3
GO:0051668	localization within membrane	5.989617e-3
GO:0015696	ammonium transport	6.029719e-3
GO:0032374	regulation of cholesterol transport	6.036504e-3
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	6.113618e-3
GO:0006396	RNA processing	6.208340e-3
GO:0006366	transcription from RNA polymerase II promoter	6.220323e-3
GO:0046466	membrane lipid catabolic process	6.264456e-3
GO:0001574	ganglioside biosynthetic process	6.331945e-3
GO:0032812	positive regulation of epinephrine secretion	6.366116e-3
GO:0070253	somatostatin secretion	6.366116e-3
GO:0034162	toll-like receptor 9 signaling pathway	6.366116e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	6.446211e-3
GO:0009258	10-formyltetrahydrofolate catabolic process	6.446211e-3
GO:0051177	meiotic sister chromatid cohesion	6.446211e-3
GO:0044070	regulation of anion transport	6.506764e-3
GO:0065001	specification of axis polarity	6.523590e-3
GO:0003062	regulation of heart rate by chemical signal	6.523590e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	6.543954e-3
GO:0000090	mitotic anaphase	6.798372e-3
GO:0006563	L-serine metabolic process	6.920479e-3
GO:0032682	negative regulation of chemokine production	6.962619e-3
GO:0035284	brain segmentation	7.117438e-3
GO:0070076	histone lysine demethylation	7.159931e-3
GO:0048708	astrocyte differentiation	7.230459e-3
GO:0006670	sphingosine metabolic process	7.288507e-3
GO:0006544	glycine metabolic process	7.289142e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	7.290690e-3
GO:0034446	substrate adhesion-dependent cell spreading	7.366679e-3
GO:0060535	trachea cartilage morphogenesis	7.471763e-3
GO:0030037	actin filament reorganization involved in cell cycle	7.522596e-3
GO:0071294	cellular response to zinc ion	7.540521e-3
GO:0006998	nuclear envelope organization	7.630514e-3
GO:0060291	long-term synaptic potentiation	7.809324e-3
GO:0003016	respiratory system process	7.814432e-3
GO:0043984	histone H4-K16 acetylation	7.824501e-3
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	8.000452e-3
GO:0010835	regulation of protein ADP-ribosylation	8.000452e-3
GO:0010994	free ubiquitin chain polymerization	8.000452e-3
GO:0051580	regulation of neurotransmitter uptake	8.026627e-3
GO:0051322	anaphase	8.069361e-3
GO:0009152	purine ribonucleotide biosynthetic process	8.111964e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	8.120573e-3
GO:0060014	granulosa cell differentiation	8.170061e-3
GO:0048702	embryonic neurocranium morphogenesis	8.170061e-3
GO:0045987	positive regulation of smooth muscle contraction	8.171302e-3
GO:0070093	negative regulation of glucagon secretion	8.349785e-3
GO:0090245	axis elongation involved in somitogenesis	8.349785e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	8.349785e-3
GO:0030262	apoptotic nuclear change	8.363996e-3
GO:0006556	S-adenosylmethionine biosynthetic process	8.501185e-3
GO:0006828	manganese ion transport	8.503691e-3
GO:0018202	peptidyl-histidine modification	8.589338e-3
GO:0006273	lagging strand elongation	8.730096e-3
GO:0032506	cytokinetic process	8.869386e-3
GO:0040001	establishment of mitotic spindle localization	9.030475e-3
GO:0090205	positive regulation of cholesterol metabolic process	9.117102e-3
GO:0001661	conditioned taste aversion	9.117102e-3
GO:0042273	ribosomal large subunit biogenesis	9.186208e-3
GO:0048002	antigen processing and presentation of peptide antigen	9.242605e-3
GO:0090280	positive regulation of calcium ion import	9.300207e-3
GO:0072086	specification of loop of Henle identity	9.300207e-3
GO:0051298	centrosome duplication	9.420967e-3
GO:0021979	hypothalamus cell differentiation	9.428541e-3
GO:2000251	positive regulation of actin cytoskeleton reorganization	9.449491e-3
GO:0021877	forebrain neuron fate commitment	9.451554e-3
GO:0021562	vestibulocochlear nerve development	9.502812e-3
GO:0046340	diacylglycerol catabolic process	9.502812e-3
GO:0021987	cerebral cortex development	9.596522e-3
GO:0060561	apoptosis involved in morphogenesis	9.675298e-3
GO:0072081	specification of nephron tubule identity	9.787782e-3
GO:0034766	negative regulation of ion transmembrane transport	9.877264e-3
GO:0019402	galactitol metabolic process	9.899691e-3
GO:0006564	L-serine biosynthetic process	9.900781e-3
GO:0030149	sphingolipid catabolic process	1.019385e-2
GO:0010159	specification of organ position	1.024035e-2
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1.032360e-2
GO:0010669	epithelial structure maintenance	1.059912e-2
GO:0031064	negative regulation of histone deacetylation	1.091144e-2
GO:0006173	dADP biosynthetic process	1.094687e-2
GO:0021535	cell migration in hindbrain	1.107329e-2
GO:0045948	positive regulation of translational initiation	1.108956e-2
GO:0032012	regulation of ARF protein signal transduction	1.111909e-2
GO:0042255	ribosome assembly	1.114286e-2
GO:0014044	Schwann cell development	1.118579e-2
GO:0000413	protein peptidyl-prolyl isomerization	1.124692e-2
GO:0006550	isoleucine catabolic process	1.132964e-2
GO:0009098	leucine biosynthetic process	1.132964e-2
GO:0031860	telomeric 3' overhang formation	1.133397e-2
GO:0043456	regulation of pentose-phosphate shunt	1.133397e-2
GO:0009446	putrescine biosynthetic process	1.133397e-2
GO:0018872	arsonoacetate metabolic process	1.133397e-2
GO:0016056	rhodopsin mediated signaling pathway	1.144809e-2
GO:0051585	negative regulation of dopamine uptake	1.174581e-2
GO:0050812	regulation of acyl-CoA biosynthetic process	1.174581e-2
GO:0070495	negative regulation of thrombin receptor signaling pathway	1.174581e-2
GO:0051622	negative regulation of norepinephrine uptake	1.174581e-2
GO:0035881	amacrine cell differentiation	1.174581e-2
GO:0003108	negative regulation of the force of heart contraction by chemical signal	1.174581e-2
GO:0023021	termination of signal transduction	1.174581e-2
GO:0006353	transcription termination, DNA-dependent	1.184728e-2
GO:0060648	mammary gland bud morphogenesis	1.189591e-2
GO:2000143	negative regulation of transcription initiation, DNA-dependent	1.192647e-2
GO:0000416	positive regulation of histone H3-K36 methylation	1.192647e-2
GO:0009153	purine deoxyribonucleotide biosynthetic process	1.195039e-2
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.197629e-2
GO:0043901	negative regulation of multi-organism process	1.198710e-2
GO:0071529	cementum mineralization	1.202607e-2
GO:0072610	interleukin-12 secretion	1.202607e-2
GO:0002074	extraocular skeletal muscle development	1.202607e-2
GO:0002408	myeloid dendritic cell chemotaxis	1.202607e-2
GO:0010390	histone monoubiquitination	1.210649e-2
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	1.218904e-2
GO:0072608	interleukin-10 secretion	1.218904e-2
GO:0090198	negative regulation of chemokine secretion	1.218904e-2
GO:0051660	establishment of centrosome localization	1.218904e-2
GO:0043311	positive regulation of eosinophil degranulation	1.218904e-2
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.218904e-2
GO:0021540	corpus callosum morphogenesis	1.218904e-2
GO:0035926	chemokine (C-C motif) ligand 2 secretion	1.218904e-2
GO:0035646	endosome to melanosome transport	1.221968e-2
GO:0018184	protein polyamination	1.221968e-2
GO:0046359	butyrate catabolic process	1.221968e-2
GO:0016095	polyprenol catabolic process	1.221968e-2
GO:0006272	leading strand elongation	1.221968e-2
GO:0040032	post-embryonic body morphogenesis	1.225224e-2
GO:0016071	mRNA metabolic process	1.247226e-2
GO:0009789	positive regulation of abscisic acid mediated signaling pathway	1.303260e-2
GO:0010870	positive regulation of receptor biosynthetic process	1.326631e-2
GO:0046325	negative regulation of glucose import	1.332586e-2
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	1.372141e-2
GO:0001771	immunological synapse formation	1.377137e-2
GO:0006406	mRNA export from nucleus	1.386259e-2
GO:0021615	glossopharyngeal nerve morphogenesis	1.396715e-2
GO:0008654	phospholipid biosynthetic process	1.427704e-2
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.463398e-2
GO:0051685	maintenance of ER location	1.464632e-2
GO:0030490	maturation of SSU-rRNA	1.465760e-2
GO:0072107	positive regulation of ureteric bud formation	1.474590e-2
GO:0032933	SREBP-mediated signaling pathway	1.484194e-2
GO:0032765	positive regulation of mast cell cytokine production	1.486051e-2
GO:0046165	alcohol biosynthetic process	1.505927e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.514276e-2
GO:0033136	serine phosphorylation of STAT3 protein	1.514276e-2
GO:0019348	dolichol metabolic process	1.514276e-2
GO:0035518	histone H2A monoubiquitination	1.515016e-2
GO:0042696	menarche	1.525090e-2
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	1.534877e-2
GO:0061028	establishment of endothelial barrier	1.560168e-2
GO:0015886	heme transport	1.565976e-2
GO:0019987	negative regulation of anti-apoptosis	1.591720e-2
GO:0032008	positive regulation of TOR signaling cascade	1.599458e-2
GO:2000573	positive regulation of DNA biosynthetic process	1.613130e-2
GO:0000093	mitotic telophase	1.613130e-2
GO:0006270	DNA-dependent DNA replication initiation	1.627968e-2
GO:0006119	oxidative phosphorylation	1.635895e-2
GO:0090279	regulation of calcium ion import	1.665163e-2
GO:0046718	entry of virus into host cell	1.685009e-2
GO:0043628	ncRNA 3'-end processing	1.689688e-2
GO:0006172	ADP biosynthetic process	1.689688e-2
GO:0045906	negative regulation of vasoconstriction	1.709738e-2
GO:0050779	RNA destabilization	1.709738e-2
GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling	1.720585e-2
GO:0030968	endoplasmic reticulum unfolded protein response	1.722181e-2
GO:0048752	semicircular canal morphogenesis	1.722855e-2
GO:0051898	negative regulation of protein kinase B signaling cascade	1.757910e-2
GO:0010874	regulation of cholesterol efflux	1.757910e-2
GO:0031167	rRNA methylation	1.762439e-2
GO:0035967	cellular response to topologically incorrect protein	1.775087e-2
GO:0021569	rhombomere 3 development	1.781772e-2
GO:0001768	establishment of T cell polarity	1.784550e-2
GO:0016090	prenol metabolic process	1.788121e-2
GO:0033490	cholesterol biosynthetic process via lathosterol	1.789084e-2
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.789084e-2
GO:0071279	cellular response to cobalt ion	1.789084e-2
GO:0042376	phylloquinone catabolic process	1.789084e-2
GO:0010637	negative regulation of mitochondrial fusion	1.789084e-2
GO:0017126	nucleologenesis	1.789084e-2
GO:0030150	protein import into mitochondrial matrix	1.789084e-2
GO:0033085	negative regulation of T cell differentiation in thymus	1.807913e-2
GO:0021678	third ventricle development	1.828487e-2
GO:0021795	cerebral cortex cell migration	1.852566e-2
GO:0070947	neutrophil mediated killing of fungus	1.853217e-2
GO:0051030	snRNA transport	1.853217e-2
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	1.853217e-2
GO:0006189	'de novo' IMP biosynthetic process	1.853217e-2
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	1.853217e-2
GO:0032108	negative regulation of response to nutrient levels	1.854053e-2
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	1.864082e-2
GO:0045342	MHC class II biosynthetic process	1.883861e-2
GO:0043091	L-arginine import	1.883861e-2
GO:0070839	divalent metal ion export	1.883861e-2
GO:0006876	cellular cadmium ion homeostasis	1.883861e-2
GO:0015707	nitrite transport	1.883861e-2
GO:0032632	interleukin-3 production	1.883861e-2
GO:0007098	centrosome cycle	1.884336e-2
GO:0001878	response to yeast	1.913769e-2
GO:0003310	pancreatic A cell differentiation	1.919349e-2
GO:0015684	ferrous iron transport	1.920194e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0046477	glycosylceramide catabolic process	1.695751e-14
GO:0019673	GDP-mannose metabolic process	1.138116e-10
GO:0035269	protein O-linked mannosylation	1.278721e-10
GO:0046479	glycosphingolipid catabolic process	1.407510e-10
GO:0019348	dolichol metabolic process	5.192265e-10
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.192265e-10
GO:0006677	glycosylceramide metabolic process	7.357993e-10
GO:0030240	skeletal muscle thin filament assembly	2.013869e-9
GO:0090083	regulation of inclusion body assembly	2.856457e-9
GO:0019377	glycolipid catabolic process	1.159828e-8
GO:0006396	RNA processing	1.239272e-8
GO:0044248	cellular catabolic process	1.592039e-8
GO:0006680	glucosylceramide catabolic process	1.633663e-8
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.971821e-8
GO:0043503	skeletal muscle fiber adaptation	1.742659e-7
GO:0006013	mannose metabolic process	4.909894e-7
GO:0034641	cellular nitrogen compound metabolic process	5.588003e-7
GO:0006139	nucleobase-containing compound metabolic process	5.762381e-7
GO:0014866	skeletal myofibril assembly	5.950279e-7
GO:0002098	tRNA wobble uridine modification	8.599318e-7
GO:0016139	glycoside catabolic process	8.611878e-7
GO:0006493	protein O-linked glycosylation	1.030879e-6
GO:0061084	negative regulation of protein refolding	1.530904e-6
GO:0034227	tRNA thio-modification	1.695758e-6
GO:0016236	macroautophagy	3.780690e-6
GO:0006678	glucosylceramide metabolic process	3.828022e-6
GO:0016574	histone ubiquitination	4.283964e-6
GO:0016071	mRNA metabolic process	4.415892e-6
GO:0034660	ncRNA metabolic process	5.004308e-6
GO:0009056	catabolic process	5.361525e-6
GO:0035645	enteric smooth muscle cell differentiation	6.043014e-6
GO:0007497	posterior midgut development	6.043014e-6
GO:0000956	nuclear-transcribed mRNA catabolic process	6.280156e-6
GO:0032481	positive regulation of type I interferon production	6.590457e-6
GO:0009057	macromolecule catabolic process	7.803699e-6
GO:0032515	negative regulation of phosphoprotein phosphatase activity	9.832258e-6
GO:0015780	nucleotide-sugar transport	1.092907e-5
GO:0034655	nucleobase-containing compound catabolic process	1.203682e-5
GO:0008334	histone mRNA metabolic process	1.240983e-5
GO:0044270	cellular nitrogen compound catabolic process	1.304020e-5
GO:0015992	proton transport	1.326396e-5
GO:0033238	regulation of cellular amine metabolic process	1.566457e-5
GO:0021528	commissural neuron differentiation in spinal cord	1.765020e-5
GO:0006807	nitrogen compound metabolic process	1.773761e-5
GO:0046700	heterocycle catabolic process	1.864660e-5
GO:0003096	renal sodium ion transport	1.956480e-5
GO:0032782	bile acid secretion	1.956480e-5
GO:0051351	positive regulation of ligase activity	1.964096e-5
GO:0006818	hydrogen transport	2.006608e-5
GO:0045345	positive regulation of MHC class I biosynthetic process	2.011406e-5
GO:0009154	purine ribonucleotide catabolic process	2.045853e-5
GO:0006657	CDP-choline pathway	2.132558e-5
GO:0006195	purine nucleotide catabolic process	2.201368e-5
GO:0009144	purine nucleoside triphosphate metabolic process	2.201835e-5
GO:0006402	mRNA catabolic process	2.242483e-5
GO:0007051	spindle organization	2.286821e-5
GO:0072523	purine-containing compound catabolic process	2.429632e-5
GO:0009205	purine ribonucleoside triphosphate metabolic process	2.514878e-5
GO:0009141	nucleoside triphosphate metabolic process	2.550359e-5
GO:0034470	ncRNA processing	2.591815e-5
GO:0009166	nucleotide catabolic process	2.625697e-5
GO:0009259	ribonucleotide metabolic process	2.966292e-5
GO:0009199	ribonucleoside triphosphate metabolic process	2.966314e-5
GO:0009207	purine ribonucleoside triphosphate catabolic process	3.059803e-5
GO:0070534	protein K63-linked ubiquitination	3.154447e-5
GO:0010467	gene expression	3.499042e-5
GO:0009261	ribonucleotide catabolic process	3.597064e-5
GO:0021570	rhombomere 4 development	3.710982e-5
GO:0009143	nucleoside triphosphate catabolic process	3.720745e-5
GO:0070925	organelle assembly	3.987079e-5
GO:0006401	RNA catabolic process	4.050719e-5
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	4.769388e-5
GO:0000045	autophagic vacuole assembly	5.180620e-5
GO:0009146	purine nucleoside triphosphate catabolic process	5.430065e-5
GO:0009150	purine ribonucleotide metabolic process	5.504216e-5
GO:0022613	ribonucleoprotein complex biogenesis	5.665536e-5
GO:0045343	regulation of MHC class I biosynthetic process	6.415774e-5
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	6.540512e-5
GO:0032513	negative regulation of protein phosphatase type 2B activity	6.791871e-5
GO:0016226	iron-sulfur cluster assembly	6.939358e-5
GO:0071843	cellular component biogenesis at cellular level	7.514462e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	7.822543e-5
GO:0006625	protein targeting to peroxisome	8.274844e-5
GO:0032727	positive regulation of interferon-alpha production	8.810037e-5
GO:0006200	ATP catabolic process	8.906663e-5
GO:0051645	Golgi localization	9.210374e-5
GO:0060047	heart contraction	9.782122e-5
GO:0048484	enteric nervous system development	9.892487e-5
GO:0032479	regulation of type I interferon production	1.024457e-4
GO:0006163	purine nucleotide metabolic process	1.028834e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	1.064661e-4
GO:2000781	positive regulation of double-strand break repair	1.064661e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.093973e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.093973e-4
GO:0072643	interferon-gamma secretion	1.093973e-4
GO:0090198	negative regulation of chemokine secretion	1.093973e-4
GO:0072608	interleukin-10 secretion	1.093973e-4
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	1.093973e-4
GO:0032707	negative regulation of interleukin-23 production	1.093973e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	1.093973e-4
GO:0035926	chemokine (C-C motif) ligand 2 secretion	1.093973e-4
GO:0045362	positive regulation of interleukin-1 biosynthetic process	1.093973e-4
GO:0043311	positive regulation of eosinophil degranulation	1.093973e-4
GO:0090304	nucleic acid metabolic process	1.172489e-4
GO:0043316	cytotoxic T cell degranulation	1.226962e-4
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.226962e-4
GO:0033522	histone H2A ubiquitination	1.259149e-4
GO:0030433	ER-associated protein catabolic process	1.453206e-4
GO:0007340	acrosome reaction	1.549454e-4
GO:0042743	hydrogen peroxide metabolic process	1.596647e-4
GO:0051488	activation of anaphase-promoting complex activity	1.619161e-4
GO:0046688	response to copper ion	1.627234e-4
GO:0060005	vestibular reflex	1.656983e-4
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.669674e-4
GO:0016072	rRNA metabolic process	1.776184e-4
GO:0060048	cardiac muscle contraction	1.958020e-4
GO:0090169	regulation of spindle assembly	2.019832e-4
GO:0090234	regulation of kinetochore assembly	2.019832e-4
GO:0043491	protein kinase B signaling cascade	2.062783e-4
GO:0085020	protein K6-linked ubiquitination	2.072011e-4
GO:0016567	protein ubiquitination	2.157674e-4
GO:0097029	mature dendritic cell differentiation	2.167470e-4
GO:0040040	thermosensory behavior	2.167470e-4
GO:0051775	response to redox state	2.167470e-4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	2.223017e-4
GO:0061099	negative regulation of protein tyrosine kinase activity	2.307391e-4
GO:0090084	negative regulation of inclusion body assembly	2.592649e-4
GO:0090086	negative regulation of protein deubiquitination	2.675020e-4
GO:0010845	positive regulation of reciprocal meiotic recombination	2.736626e-4
GO:0033239	negative regulation of cellular amine metabolic process	2.874481e-4
GO:2000272	negative regulation of receptor activity	2.884826e-4
GO:0042384	cilium assembly	2.982301e-4
GO:0030149	sphingolipid catabolic process	3.021807e-4
GO:0046514	ceramide catabolic process	3.085306e-4
GO:0015991	ATP hydrolysis coupled proton transport	3.218808e-4
GO:0006664	glycolipid metabolic process	3.408963e-4
GO:0006397	mRNA processing	3.628114e-4
GO:0006914	autophagy	3.664562e-4
GO:0000379	tRNA-type intron splice site recognition and cleavage	3.671698e-4
GO:2000649	regulation of sodium ion transmembrane transporter activity	3.677389e-4
GO:0044265	cellular macromolecule catabolic process	3.677448e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	3.683033e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	3.828709e-4
GO:0045792	negative regulation of cell size	3.893389e-4
GO:0010390	histone monoubiquitination	4.286680e-4
GO:0032446	protein modification by small protein conjugation	4.343102e-4
GO:0008637	apoptotic mitochondrial changes	4.515810e-4
GO:0018243	protein O-linked glycosylation via threonine	4.576571e-4
GO:0018242	protein O-linked glycosylation via serine	4.576571e-4
GO:0045787	positive regulation of cell cycle	4.721487e-4
GO:0048246	macrophage chemotaxis	4.779925e-4
GO:0009620	response to fungus	4.810769e-4
GO:0043403	skeletal muscle tissue regeneration	5.011660e-4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	5.165622e-4
GO:0016070	RNA metabolic process	5.396146e-4
GO:0006220	pyrimidine nucleotide metabolic process	5.400135e-4
GO:0000147	actin cortical patch assembly	5.479878e-4
GO:0046034	ATP metabolic process	5.599528e-4
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	5.681330e-4
GO:2000682	positive regulation of rubidium ion transport	5.681330e-4
GO:0001682	tRNA 5'-leader removal	5.681330e-4
GO:0016078	tRNA catabolic process	5.681330e-4
GO:0035826	rubidium ion transport	5.681330e-4
GO:0008654	phospholipid biosynthetic process	5.950020e-4
GO:0060658	nipple morphogenesis	6.120852e-4
GO:0072521	purine-containing compound metabolic process	6.165394e-4
GO:0009218	pyrimidine ribonucleotide metabolic process	6.325160e-4
GO:0016090	prenol metabolic process	6.378260e-4
GO:0055072	iron ion homeostasis	6.666498e-4
GO:0051321	meiotic cell cycle	6.726122e-4
GO:0080164	regulation of nitric oxide metabolic process	6.780228e-4
GO:0006683	galactosylceramide catabolic process	6.780228e-4
GO:0003015	heart process	6.933237e-4
GO:0016558	protein import into peroxisome matrix	6.972353e-4
GO:0051443	positive regulation of ubiquitin-protein ligase activity	7.056857e-4
GO:0006412	translation	7.073553e-4
GO:0046364	monosaccharide biosynthetic process	7.144574e-4
GO:0006513	protein monoubiquitination	7.600051e-4
GO:0006213	pyrimidine nucleoside metabolic process	7.621156e-4
GO:0006364	rRNA processing	7.887970e-4
GO:0050746	regulation of lipoprotein metabolic process	7.973880e-4
GO:0010927	cellular component assembly involved in morphogenesis	8.021564e-4
GO:0043949	regulation of cAMP-mediated signaling	8.402495e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	8.519462e-4
GO:0051340	regulation of ligase activity	8.664272e-4
GO:0046548	retinal rod cell development	8.843434e-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	8.869110e-4
GO:0043555	regulation of translation in response to stress	9.171774e-4
GO:0070562	regulation of vitamin D receptor signaling pathway	9.343082e-4
GO:0051661	maintenance of centrosome location	9.502175e-4
GO:0033240	positive regulation of cellular amine metabolic process	9.744184e-4
GO:0008380	RNA splicing	9.945963e-4
GO:0009996	negative regulation of cell fate specification	1.035100e-3
GO:0009117	nucleotide metabolic process	1.044117e-3
GO:0044260	cellular macromolecule metabolic process	1.056880e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.058441e-3
GO:0022417	protein maturation by protein folding	1.058441e-3
GO:0018158	protein oxidation	1.058441e-3
GO:0010454	negative regulation of cell fate commitment	1.066061e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	1.069334e-3
GO:0071044	histone mRNA catabolic process	1.118594e-3
GO:0015696	ammonium transport	1.118594e-3
GO:0060674	placenta blood vessel development	1.131913e-3
GO:0051549	positive regulation of keratinocyte migration	1.139185e-3
GO:0032728	positive regulation of interferon-beta production	1.155637e-3
GO:0045083	negative regulation of interleukin-12 biosynthetic process	1.173196e-3
GO:0001881	receptor recycling	1.173196e-3
GO:0055089	fatty acid homeostasis	1.182438e-3
GO:0000305	response to oxygen radical	1.259169e-3
GO:0006457	protein folding	1.362916e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.372017e-3
GO:0043484	regulation of RNA splicing	1.374503e-3
GO:0043558	regulation of translational initiation in response to stress	1.384713e-3
GO:0022403	cell cycle phase	1.497306e-3
GO:0007494	midgut development	1.498013e-3
GO:0032347	regulation of aldosterone biosynthetic process	1.524346e-3
GO:0050691	regulation of defense response to virus by host	1.528835e-3
GO:0034661	ncRNA catabolic process	1.543691e-3
GO:0016137	glycoside metabolic process	1.602226e-3
GO:0031274	positive regulation of pseudopodium assembly	1.606715e-3
GO:0044237	cellular metabolic process	1.623274e-3
GO:0000375	RNA splicing, via transesterification reactions	1.623323e-3
GO:0034587	piRNA metabolic process	1.684257e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.722300e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.722300e-3
GO:0030328	prenylcysteine catabolic process	1.722300e-3
GO:0070627	ferrous iron import	1.731698e-3
GO:0015676	vanadium ion transport	1.731698e-3
GO:0015692	lead ion transport	1.731698e-3
GO:0019319	hexose biosynthetic process	1.787112e-3
GO:0000279	M phase	1.806966e-3
GO:0034442	regulation of lipoprotein oxidation	1.832476e-3
GO:0033119	negative regulation of RNA splicing	1.853272e-3
GO:0050748	negative regulation of lipoprotein metabolic process	1.869515e-3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	1.911404e-3
GO:0002339	B cell selection	1.987091e-3
GO:0006398	histone mRNA 3'-end processing	1.998552e-3
GO:0006172	ADP biosynthetic process	1.998552e-3
GO:0055086	nucleobase-containing small molecule metabolic process	2.005796e-3
GO:0002825	regulation of T-helper 1 type immune response	2.017999e-3
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	2.050423e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	2.063904e-3
GO:0019430	removal of superoxide radicals	2.075805e-3
GO:0000413	protein peptidyl-prolyl isomerization	2.076553e-3
GO:0045922	negative regulation of fatty acid metabolic process	2.077591e-3
GO:0032647	regulation of interferon-alpha production	2.121789e-3
GO:0001732	formation of translation initiation complex	2.125123e-3
GO:0046007	negative regulation of activated T cell proliferation	2.176139e-3
GO:0006259	DNA metabolic process	2.179478e-3
GO:0072527	pyrimidine-containing compound metabolic process	2.216606e-3
GO:0006222	UMP biosynthetic process	2.252097e-3
GO:0032349	positive regulation of aldosterone biosynthetic process	2.255022e-3
GO:0051004	regulation of lipoprotein lipase activity	2.362007e-3
GO:0000188	inactivation of MAPK activity	2.373100e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.408503e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.440815e-3
GO:0060534	trachea cartilage development	2.440815e-3
GO:0043526	neuroprotection	2.515038e-3
GO:0001756	somitogenesis	2.610581e-3
GO:0021569	rhombomere 3 development	2.613094e-3
GO:0051289	protein homotetramerization	2.774481e-3
GO:0006405	RNA export from nucleus	2.779396e-3
GO:0070914	UV-damage excision repair	2.810521e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	2.810521e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	2.869672e-3
GO:0060017	parathyroid gland development	2.869672e-3
GO:0033120	positive regulation of RNA splicing	2.904013e-3
GO:0035426	extracellular matrix-cell signaling	2.906108e-3
GO:0030033	microvillus assembly	2.908602e-3
GO:0046466	membrane lipid catabolic process	2.945483e-3
GO:0070535	histone H2A K63-linked ubiquitination	2.952525e-3
GO:0016142	O-glycoside catabolic process	2.952525e-3
GO:0042443	phenylethylamine metabolic process	2.952525e-3
GO:0031272	regulation of pseudopodium assembly	2.978535e-3
GO:0035082	axoneme assembly	2.979010e-3
GO:0006004	fucose metabolic process	2.979010e-3
GO:0046434	organophosphate catabolic process	3.173893e-3
GO:0051225	spindle assembly	3.173990e-3
GO:0060716	labyrinthine layer blood vessel development	3.181471e-3
GO:0030163	protein catabolic process	3.194982e-3
GO:0009133	nucleoside diphosphate biosynthetic process	3.218562e-3
GO:0035307	positive regulation of protein dephosphorylation	3.277377e-3
GO:0014826	vein smooth muscle contraction	3.306745e-3
GO:0034224	cellular response to zinc ion starvation	3.385573e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	3.385573e-3
GO:0006043	glucosamine catabolic process	3.400044e-3
GO:0042069	regulation of catecholamine metabolic process	3.437265e-3
GO:0006221	pyrimidine nucleotide biosynthetic process	3.678082e-3
GO:0002230	positive regulation of defense response to virus by host	3.691388e-3
GO:0042304	regulation of fatty acid biosynthetic process	3.712601e-3
GO:0031669	cellular response to nutrient levels	3.726035e-3
GO:0035306	positive regulation of dephosphorylation	3.772726e-3
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	3.812190e-3
GO:0006473	protein acetylation	3.824895e-3
GO:0016075	rRNA catabolic process	3.830062e-3
GO:0090085	regulation of protein deubiquitination	3.882911e-3
GO:2000043	regulation of cardiac cell fate specification	3.904201e-3
GO:0015986	ATP synthesis coupled proton transport	3.937813e-3
GO:0008634	negative regulation of survival gene product expression	3.941488e-3
GO:0002827	positive regulation of T-helper 1 type immune response	3.941488e-3
GO:0044090	positive regulation of vacuole organization	3.980851e-3
GO:0009234	menaquinone biosynthetic process	3.980851e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.003882e-3
GO:0007140	male meiosis	4.124691e-3
GO:0033962	cytoplasmic mRNA processing body assembly	4.145165e-3
GO:0035852	horizontal cell localization	4.202061e-3
GO:0035849	nephric duct elongation	4.202061e-3
GO:0043048	dolichyl monophosphate biosynthetic process	4.202061e-3
GO:0071279	cellular response to cobalt ion	4.202061e-3
GO:0035847	uterine epithelium development	4.202061e-3
GO:0070370	cellular heat acclimation	4.202061e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	4.202061e-3
GO:0035846	oviduct epithelium development	4.202061e-3
GO:0006348	chromatin silencing at telomere	4.202061e-3
GO:0010637	negative regulation of mitochondrial fusion	4.202061e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	4.202061e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	4.202061e-3
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	4.202061e-3
GO:0030261	chromosome condensation	4.220308e-3
GO:0010155	regulation of proton transport	4.241471e-3
GO:0050832	defense response to fungus	4.329933e-3
GO:0046939	nucleotide phosphorylation	4.329933e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.338261e-3
GO:0071034	CUT catabolic process	4.348639e-3
GO:0051382	kinetochore assembly	4.348639e-3
GO:0018298	protein-chromophore linkage	4.353238e-3
GO:0008033	tRNA processing	4.413922e-3
GO:0032677	regulation of interleukin-8 production	4.430309e-3
GO:0070936	protein K48-linked ubiquitination	4.432977e-3
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	4.444394e-3
GO:0006749	glutathione metabolic process	4.580987e-3
GO:0060631	regulation of meiosis I	4.726705e-3
GO:0045357	regulation of interferon-beta biosynthetic process	4.726705e-3
GO:0032007	negative regulation of TOR signaling cascade	4.799979e-3
GO:0042660	positive regulation of cell fate specification	4.917218e-3
GO:0006413	translational initiation	4.961855e-3
GO:2000036	regulation of stem cell maintenance	5.101950e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	5.110710e-3
GO:0046165	alcohol biosynthetic process	5.152681e-3
GO:0034637	cellular carbohydrate biosynthetic process	5.152681e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	5.159823e-3
GO:0002175	protein localization to paranode region of axon	5.159823e-3
GO:0051572	negative regulation of histone H3-K4 methylation	5.189660e-3
GO:0060586	multicellular organismal iron ion homeostasis	5.248395e-3
GO:0042254	ribosome biogenesis	5.474145e-3
GO:0050668	positive regulation of homocysteine metabolic process	5.492972e-3
GO:0045963	negative regulation of dopamine metabolic process	5.492972e-3
GO:0034635	glutathione transport	5.492972e-3
GO:0016073	snRNA metabolic process	5.552807e-3
GO:0006264	mitochondrial DNA replication	5.569350e-3
GO:0001826	inner cell mass cell differentiation	5.569350e-3
GO:0034755	iron ion transmembrane transport	5.589224e-3
GO:0061136	regulation of proteasomal protein catabolic process	5.686325e-3
GO:0030307	positive regulation of cell growth	5.718551e-3
GO:0007126	meiosis	5.834697e-3
GO:0042053	regulation of dopamine metabolic process	5.919986e-3
GO:0072528	pyrimidine-containing compound biosynthetic process	6.106035e-3
GO:0071545	inositol phosphate catabolic process	6.214918e-3
GO:0000303	response to superoxide	6.233011e-3
GO:0001836	release of cytochrome c from mitochondria	6.302315e-3
GO:0006687	glycosphingolipid metabolic process	6.333840e-3
GO:0048255	mRNA stabilization	6.373176e-3
GO:0010950	positive regulation of endopeptidase activity	6.375814e-3
GO:0045217	cell-cell junction maintenance	6.382647e-3
GO:0033128	negative regulation of histone phosphorylation	6.459498e-3
GO:0010501	RNA secondary structure unwinding	6.459498e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	6.459498e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6.466234e-3
GO:0006475	internal protein amino acid acetylation	6.691164e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	6.733206e-3
GO:0051895	negative regulation of focal adhesion assembly	6.913102e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	6.935791e-3
GO:0090310	negative regulation of methylation-dependent chromatin silencing	6.935791e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	6.935791e-3
GO:0045046	protein import into peroxisome membrane	6.935791e-3
GO:0032094	response to food	6.939089e-3
GO:0007141	male meiosis I	6.944664e-3
GO:0043320	natural killer cell degranulation	6.966196e-3
GO:0018126	protein hydroxylation	7.066782e-3
GO:0007033	vacuole organization	7.308838e-3
GO:0045906	negative regulation of vasoconstriction	7.495963e-3
GO:0014043	negative regulation of neuron maturation	7.495963e-3
GO:0048384	retinoic acid receptor signaling pathway	7.689408e-3
GO:0045872	positive regulation of rhodopsin gene expression	7.721308e-3
GO:2000653	regulation of genetic imprinting	7.721308e-3
GO:0034276	kynurenic acid biosynthetic process	7.721308e-3
GO:0002534	cytokine production involved in inflammatory response	7.721308e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	7.721308e-3
GO:0002159	desmosome assembly	7.721308e-3
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	7.769143e-3
GO:0042264	peptidyl-aspartic acid hydroxylation	7.769143e-3
GO:0001892	embryonic placenta development	7.985949e-3
GO:0007031	peroxisome organization	8.054054e-3
GO:0048752	semicircular canal morphogenesis	8.057713e-3
GO:0006885	regulation of pH	8.188558e-3
GO:0006406	mRNA export from nucleus	8.383642e-3
GO:0042744	hydrogen peroxide catabolic process	8.414755e-3
GO:0051030	snRNA transport	8.418408e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	8.418408e-3
GO:0000492	box C/D snoRNP assembly	8.418408e-3
GO:0019509	L-methionine salvage from methylthioadenosine	8.418408e-3
GO:0009260	ribonucleotide biosynthetic process	8.447119e-3
GO:0035434	copper ion transmembrane transport	8.492344e-3
GO:0060535	trachea cartilage morphogenesis	8.492344e-3
GO:0046173	polyol biosynthetic process	8.504143e-3
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	8.620491e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	8.620491e-3
GO:0007176	regulation of epidermal growth factor-activated receptor activity	8.744570e-3
GO:0006612	protein targeting to membrane	8.942318e-3
GO:0071108	protein K48-linked deubiquitination	9.141777e-3
GO:0042350	GDP-L-fucose biosynthetic process	9.262483e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	9.295490e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	9.295490e-3
GO:0046039	GTP metabolic process	9.377886e-3
GO:0071267	L-methionine salvage	9.531592e-3
GO:0008156	negative regulation of DNA replication	9.718461e-3
GO:0019217	regulation of fatty acid metabolic process	1.030759e-2
GO:0018393	internal peptidyl-lysine acetylation	1.033947e-2
GO:0060319	primitive erythrocyte differentiation	1.037228e-2
GO:0046322	negative regulation of fatty acid oxidation	1.037228e-2
GO:0006879	cellular iron ion homeostasis	1.053358e-2
GO:0060709	glycogen cell development involved in embryonic placenta development	1.081251e-2
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.081251e-2
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1.081251e-2
GO:0002537	nitric oxide production involved in inflammatory response	1.081251e-2
GO:0035282	segmentation	1.083987e-2
GO:0006228	UTP biosynthetic process	1.084074e-2
GO:0006165	nucleoside diphosphate phosphorylation	1.084074e-2
GO:0046483	heterocycle metabolic process	1.085122e-2
GO:0060711	labyrinthine layer development	1.086547e-2
GO:0051438	regulation of ubiquitin-protein ligase activity	1.088698e-2
GO:0010520	regulation of reciprocal meiotic recombination	1.091990e-2
GO:0021612	facial nerve structural organization	1.091990e-2
GO:0001755	neural crest cell migration	1.113008e-2
GO:0032107	regulation of response to nutrient levels	1.123631e-2
GO:0006415	translational termination	1.141784e-2
GO:0008635	activation of caspase activity by cytochrome c	1.168043e-2
GO:0030277	maintenance of gastrointestinal epithelium	1.168726e-2
GO:0009132	nucleoside diphosphate metabolic process	1.172071e-2
GO:0010741	negative regulation of intracellular protein kinase cascade	1.182274e-2
GO:0009267	cellular response to starvation	1.189377e-2
GO:0006399	tRNA metabolic process	1.197195e-2
GO:0018394	peptidyl-lysine acetylation	1.226480e-2
GO:0071985	multivesicular body sorting pathway	1.234393e-2
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.234393e-2
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.234393e-2
GO:0043973	histone H3-K4 acetylation	1.234393e-2
GO:0060729	intestinal epithelial structure maintenance	1.234680e-2
GO:0060482	lobar bronchus development	1.252191e-2
GO:0045618	positive regulation of keratinocyte differentiation	1.252191e-2
GO:0070634	transepithelial ammonium transport	1.254835e-2
GO:0061113	pancreas morphogenesis	1.254835e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.275557e-2
GO:0014041	regulation of neuron maturation	1.278104e-2
GO:0046031	ADP metabolic process	1.278104e-2
GO:0060166	olfactory pit development	1.279711e-2
GO:0035444	nickel ion transmembrane transport	1.279711e-2
GO:0031999	negative regulation of fatty acid beta-oxidation	1.279711e-2
GO:0071956	cellular component maintenance at cellular level	1.283383e-2
GO:0030970	retrograde protein transport, ER to cytosol	1.287904e-2
GO:0001913	T cell mediated cytotoxicity	1.287904e-2
GO:0032006	regulation of TOR signaling cascade	1.290124e-2
GO:0010269	response to selenium ion	1.302629e-2
GO:0006352	transcription initiation, DNA-dependent	1.318956e-2
GO:0070979	protein K11-linked ubiquitination	1.322442e-2
GO:0032413	negative regulation of ion transmembrane transporter activity	1.323742e-2
GO:0044085	cellular component biogenesis	1.344053e-2
GO:0043309	regulation of eosinophil degranulation	1.348786e-2
GO:0097152	mesenchymal cell apoptosis	1.348786e-2
GO:0042137	sequestering of neurotransmitter	1.348786e-2
GO:0034633	retinol transport	1.348786e-2
GO:0009597	detection of virus	1.348786e-2
GO:0035674	tricarboxylic acid transmembrane transport	1.348786e-2
GO:0009145	purine nucleoside triphosphate biosynthetic process	1.365152e-2
GO:0023021	termination of signal transduction	1.366424e-2
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.366424e-2
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.366424e-2
GO:0051647	nucleus localization	1.382344e-2
GO:0008629	induction of apoptosis by intracellular signals	1.405822e-2
GO:0016180	snRNA processing	1.416871e-2
GO:0045604	regulation of epidermal cell differentiation	1.444529e-2
GO:0042119	neutrophil activation	1.445468e-2
GO:0006516	glycoprotein catabolic process	1.448231e-2
GO:0030031	cell projection assembly	1.464150e-2
GO:0046683	response to organophosphorus	1.477418e-2
GO:0061015	snRNA import into nucleus	1.477418e-2
GO:0045769	negative regulation of asymmetric cell division	1.477418e-2
GO:0035502	metanephric ureteric bud development	1.477418e-2
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	1.480908e-2
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.480908e-2
GO:0006436	tryptophanyl-tRNA aminoacylation	1.480908e-2
GO:0045047	protein targeting to ER	1.492056e-2
GO:0050665	hydrogen peroxide biosynthetic process	1.498467e-2
GO:0006183	GTP biosynthetic process	1.498467e-2
GO:0043407	negative regulation of MAP kinase activity	1.505626e-2
GO:0010887	negative regulation of cholesterol storage	1.506393e-2
GO:0042424	catecholamine catabolic process	1.535490e-2
GO:0002344	B cell affinity maturation	1.535490e-2
GO:0006828	manganese ion transport	1.552647e-2
GO:0022618	ribonucleoprotein complex assembly	1.565524e-2