Novel motif:90

name:	motif90_TTATATCGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0022614	membrane to membrane docking	2.993898e-13
GO:0048806	genitalia development	2.163844e-10
GO:0021568	rhombomere 2 development	2.417592e-10
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	2.699730e-10
GO:0021930	cerebellar granule cell precursor proliferation	2.596228e-9
GO:0043570	maintenance of DNA repeat elements	9.643254e-9
GO:0009107	lipoate biosynthetic process	1.259615e-8
GO:0007598	blood coagulation, extrinsic pathway	5.683842e-8
GO:0007016	cytoskeletal anchoring at plasma membrane	9.226772e-8
GO:0039020	pronephric nephron tubule development	1.074830e-7
GO:0035565	regulation of pronephros size	1.074830e-7
GO:0006266	DNA ligation	2.269627e-7
GO:0035112	genitalia morphogenesis	4.394819e-7
GO:0006437	tyrosyl-tRNA aminoacylation	4.464810e-7
GO:0021546	rhombomere development	4.977584e-7
GO:0032673	regulation of interleukin-4 production	5.258215e-7
GO:0009106	lipoate metabolic process	5.566230e-7
GO:0072181	mesonephric duct formation	6.014399e-7
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	6.136235e-7
GO:0022406	membrane docking	1.042586e-6
GO:0008272	sulfate transport	1.553967e-6
GO:0019319	hexose biosynthetic process	2.274211e-6
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	2.634765e-6
GO:0006303	double-strand break repair via nonhomologous end joining	3.042444e-6
GO:0006094	gluconeogenesis	3.180763e-6
GO:0035411	catenin import into nucleus	4.061677e-6
GO:0072172	mesonephric tubule formation	4.563706e-6
GO:0015074	DNA integration	4.914912e-6
GO:0042249	establishment of planar polarity of embryonic epithelium	5.820170e-6
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	5.985156e-6
GO:0032252	secretory granule localization	6.582915e-6
GO:0043111	replication fork arrest	7.085530e-6
GO:0061017	hepatoblast differentiation	8.037618e-6
GO:0051254	positive regulation of RNA metabolic process	8.566944e-6
GO:0002541	activation of plasma proteins involved in acute inflammatory response	9.455542e-6
GO:0046364	monosaccharide biosynthetic process	1.010975e-5
GO:0030902	hindbrain development	1.012754e-5
GO:0061384	heart trabecular morphogenesis	1.054265e-5
GO:0072095	regulation of branch elongation involved in ureteric bud branching	1.260033e-5
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.306279e-5
GO:0060216	definitive hemopoiesis	1.658848e-5
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	1.791305e-5
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	1.791305e-5
GO:0019047	provirus integration	2.092439e-5
GO:0061383	trabecula morphogenesis	2.122545e-5
GO:0090304	nucleic acid metabolic process	2.204447e-5
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2.388888e-5
GO:0030194	positive regulation of blood coagulation	2.701980e-5
GO:0032743	positive regulation of interleukin-2 production	3.037183e-5
GO:0006259	DNA metabolic process	3.396422e-5
GO:0048265	response to pain	3.436506e-5
GO:0007159	leukocyte cell-cell adhesion	3.660239e-5
GO:0001826	inner cell mass cell differentiation	3.708568e-5
GO:0070265	necrotic cell death	3.786744e-5
GO:0000726	non-recombinational repair	3.966042e-5
GO:0040019	positive regulation of embryonic development	3.975786e-5
GO:0031328	positive regulation of cellular biosynthetic process	4.095365e-5
GO:0021555	midbrain-hindbrain boundary morphogenesis	4.295199e-5
GO:0045893	positive regulation of transcription, DNA-dependent	4.328907e-5
GO:0002543	activation of blood coagulation via clotting cascade	4.664888e-5
GO:0051176	positive regulation of sulfur metabolic process	4.858305e-5
GO:0048566	embryonic digestive tract development	5.056661e-5
GO:0050820	positive regulation of coagulation	5.148215e-5
GO:0032571	response to vitamin K	5.209259e-5
GO:0010628	positive regulation of gene expression	5.245613e-5
GO:0051386	regulation of nerve growth factor receptor signaling pathway	5.247605e-5
GO:0051447	negative regulation of meiotic cell cycle	5.793983e-5
GO:0048388	endosomal lumen acidification	5.801399e-5
GO:0042762	regulation of sulfur metabolic process	5.815140e-5
GO:0060554	induction of necroptosis of activated-T cells	5.915315e-5
GO:0072171	mesonephric tubule morphogenesis	6.097032e-5
GO:0060437	lung growth	6.166334e-5
GO:0072378	blood coagulation, fibrin clot formation	6.448045e-5
GO:0032753	positive regulation of interleukin-4 production	6.551034e-5
GO:0009891	positive regulation of biosynthetic process	6.553392e-5
GO:0006139	nucleobase-containing compound metabolic process	7.968575e-5
GO:0009949	polarity specification of anterior/posterior axis	8.024269e-5
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	8.024269e-5
GO:0034633	retinol transport	8.204534e-5
GO:0044029	hypomethylation of CpG island	9.389291e-5
GO:2000121	regulation of removal of superoxide radicals	9.621274e-5
GO:0030538	embryonic genitalia morphogenesis	9.647930e-5
GO:0051173	positive regulation of nitrogen compound metabolic process	1.053612e-4
GO:0046666	retinal cell programmed cell death	1.107759e-4
GO:0003222	ventricular trabecular myocardium morphogenesis	1.107759e-4
GO:0006734	NADH metabolic process	1.190933e-4
GO:0048562	embryonic organ morphogenesis	1.218305e-4
GO:0048557	embryonic digestive tract morphogenesis	1.254395e-4
GO:0048625	myoblast cell fate commitment	1.301352e-4
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	1.326272e-4
GO:0030259	lipid glycosylation	1.458310e-4
GO:0002726	positive regulation of T cell cytokine production	1.582258e-4
GO:0002691	regulation of cellular extravasation	1.582258e-4
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.633605e-4
GO:0071506	cellular response to mycophenolic acid	1.633605e-4
GO:0048641	regulation of skeletal muscle tissue development	1.661906e-4
GO:0031295	T cell costimulation	1.668967e-4
GO:0030317	sperm motility	1.851441e-4
GO:0001714	endodermal cell fate specification	1.858817e-4
GO:0032892	positive regulation of organic acid transport	1.987585e-4
GO:0006560	proline metabolic process	2.261320e-4
GO:0046165	alcohol biosynthetic process	2.338756e-4
GO:0009822	alkaloid catabolic process	2.427929e-4
GO:0060337	type I interferon-mediated signaling pathway	2.577829e-4
GO:0072180	mesonephric duct morphogenesis	2.623482e-4
GO:0048266	behavioral response to pain	2.646364e-4
GO:0046827	positive regulation of protein export from nucleus	2.710778e-4
GO:0016202	regulation of striated muscle tissue development	2.715354e-4
GO:0030193	regulation of blood coagulation	2.722647e-4
GO:0034340	response to type I interferon	2.777516e-4
GO:0006733	oxidoreduction coenzyme metabolic process	2.882369e-4
GO:0048619	embryonic hindgut morphogenesis	2.925771e-4
GO:0006072	glycerol-3-phosphate metabolic process	2.986457e-4
GO:0019362	pyridine nucleotide metabolic process	3.212895e-4
GO:0021986	habenula development	3.262668e-4
GO:0050818	regulation of coagulation	3.302671e-4
GO:0045453	bone resorption	3.304975e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	3.322891e-4
GO:0032024	positive regulation of insulin secretion	3.429725e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	3.719344e-4
GO:0070498	interleukin-1-mediated signaling pathway	3.723332e-4
GO:0021903	rostrocaudal neural tube patterning	3.723332e-4
GO:0072110	glomerular mesangial cell proliferation	4.013200e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	4.013200e-4
GO:0010557	positive regulation of macromolecule biosynthetic process	4.025345e-4
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	4.115080e-4
GO:2000124	regulation of endocannabinoid signaling pathway	4.290186e-4
GO:0007600	sensory perception	4.339788e-4
GO:0034337	RNA folding	4.581333e-4
GO:0048634	regulation of muscle organ development	4.699463e-4
GO:0016070	RNA metabolic process	5.116299e-4
GO:0006561	proline biosynthetic process	5.207971e-4
GO:0023019	signal transduction involved in regulation of gene expression	5.290076e-4
GO:0090004	positive regulation of establishment of protein localization in plasma membrane	5.534183e-4
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	5.737856e-4
GO:0045047	protein targeting to ER	5.833206e-4
GO:0019233	sensory perception of pain	5.969380e-4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	6.139282e-4
GO:0046496	nicotinamide nucleotide metabolic process	6.210040e-4
GO:0035284	brain segmentation	6.651919e-4
GO:0002724	regulation of T cell cytokine production	6.891768e-4
GO:0072177	mesonephric duct development	7.055460e-4
GO:0072109	glomerular mesangium development	7.055460e-4
GO:0060343	trabecula formation	7.212269e-4
GO:0001711	endodermal cell fate commitment	7.266696e-4
GO:0035883	enteroendocrine cell differentiation	7.304781e-4
GO:0032913	negative regulation of transforming growth factor beta3 production	7.304781e-4
GO:0032600	chemokine receptor transport out of membrane raft	7.304781e-4
GO:0032597	B cell receptor transport into membrane raft	7.304781e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	7.508296e-4
GO:0044030	regulation of DNA methylation	7.714754e-4
GO:0003329	pancreatic PP cell fate commitment	7.768772e-4
GO:0003326	pancreatic A cell fate commitment	7.768772e-4
GO:2000774	positive regulation of cellular senescence	8.217453e-4
GO:0035986	senescence-associated heterochromatin focus formation	8.217453e-4
GO:0060333	interferon-gamma-mediated signaling pathway	8.219582e-4
GO:0043588	skin development	8.977047e-4
GO:0032733	positive regulation of interleukin-10 production	9.128491e-4
GO:0045995	regulation of embryonic development	9.215227e-4
GO:0051155	positive regulation of striated muscle cell differentiation	9.350912e-4
GO:0045597	positive regulation of cell differentiation	9.432026e-4
GO:0007225	patched ligand maturation	9.736953e-4
GO:0002052	positive regulation of neuroblast proliferation	9.770540e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	9.776562e-4
GO:0050850	positive regulation of calcium-mediated signaling	9.861123e-4
GO:0051053	negative regulation of DNA metabolic process	9.939254e-4
GO:0043624	cellular protein complex disassembly	9.972774e-4
GO:0016525	negative regulation of angiogenesis	1.018429e-3
GO:0048568	embryonic organ development	1.044305e-3
GO:0019674	NAD metabolic process	1.047546e-3
GO:0019441	tryptophan catabolic process to kynurenine	1.063827e-3
GO:0000710	meiotic mismatch repair	1.065773e-3
GO:0031016	pancreas development	1.066076e-3
GO:0021512	spinal cord anterior/posterior patterning	1.175202e-3
GO:0006425	glutaminyl-tRNA aminoacylation	1.175202e-3
GO:0007113	endomitotic cell cycle	1.175202e-3
GO:0002200	somatic diversification of immune receptors	1.183685e-3
GO:0016558	protein import into peroxisome matrix	1.239382e-3
GO:0050796	regulation of insulin secretion	1.287398e-3
GO:0030917	midbrain-hindbrain boundary development	1.293517e-3
GO:0033151	V(D)J recombination	1.302459e-3
GO:0021511	spinal cord patterning	1.310945e-3
GO:0046321	positive regulation of fatty acid oxidation	1.327486e-3
GO:0060347	heart trabecula formation	1.335297e-3
GO:0042118	endothelial cell activation	1.344950e-3
GO:0035564	regulation of kidney size	1.344950e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	1.364680e-3
GO:0060743	epithelial cell maturation involved in prostate gland development	1.391744e-3
GO:0051276	chromosome organization	1.417798e-3
GO:0009744	response to sucrose stimulus	1.422015e-3
GO:0035987	endodermal cell differentiation	1.440505e-3
GO:0042663	regulation of endodermal cell fate specification	1.483037e-3
GO:0043241	protein complex disassembly	1.485650e-3
GO:0042254	ribosome biogenesis	1.487250e-3
GO:0045213	neurotransmitter receptor metabolic process	1.500976e-3
GO:0042574	retinal metabolic process	1.560255e-3
GO:0070189	kynurenine metabolic process	1.608586e-3
GO:0046621	negative regulation of organ growth	1.608586e-3
GO:0060249	anatomical structure homeostasis	1.612451e-3
GO:0010867	positive regulation of triglyceride biosynthetic process	1.631275e-3
GO:0032774	RNA biosynthetic process	1.654739e-3
GO:0045444	fat cell differentiation	1.671366e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	1.709339e-3
GO:0034968	histone lysine methylation	1.723625e-3
GO:0034261	negative regulation of Ras GTPase activity	1.738891e-3
GO:0031117	positive regulation of microtubule depolymerization	1.739763e-3
GO:0033555	multicellular organismal response to stress	1.788468e-3
GO:0034770	histone H4-K20 methylation	1.788758e-3
GO:0030509	BMP signaling pathway	1.818085e-3
GO:0021532	neural tube patterning	1.820457e-3
GO:0032663	regulation of interleukin-2 production	1.879829e-3
GO:2000193	positive regulation of fatty acid transport	1.936305e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.953662e-3
GO:0090277	positive regulation of peptide hormone secretion	1.953969e-3
GO:0031018	endocrine pancreas development	1.957743e-3
GO:0006732	coenzyme metabolic process	1.989421e-3
GO:2000438	negative regulation of monocyte extravasation	1.990116e-3
GO:0080154	regulation of fertilization	1.990116e-3
GO:0035724	CD24 biosynthetic process	1.990116e-3
GO:0035723	interleukin-15-mediated signaling pathway	1.990116e-3
GO:0009108	coenzyme biosynthetic process	2.019467e-3
GO:0034637	cellular carbohydrate biosynthetic process	2.022901e-3
GO:2000111	positive regulation of macrophage apoptosis	2.049177e-3
GO:0045722	positive regulation of gluconeogenesis	2.075251e-3
GO:0045445	myoblast differentiation	2.097345e-3
GO:0010832	negative regulation of myotube differentiation	2.141310e-3
GO:0002793	positive regulation of peptide secretion	2.142693e-3
GO:0045165	cell fate commitment	2.168620e-3
GO:0006984	ER-nucleus signaling pathway	2.174828e-3
GO:0061041	regulation of wound healing	2.175062e-3
GO:0050927	positive regulation of positive chemotaxis	2.186500e-3
GO:0048808	male genitalia morphogenesis	2.236424e-3
GO:0010467	gene expression	2.241927e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	2.285089e-3
GO:0051017	actin filament bundle assembly	2.294073e-3
GO:0060677	ureteric bud elongation	2.334576e-3
GO:0060325	face morphogenesis	2.345463e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.357976e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	2.377924e-3
GO:0008633	activation of pro-apoptotic gene products	2.378338e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	2.409286e-3
GO:0002669	positive regulation of T cell anergy	2.435820e-3
GO:0034341	response to interferon-gamma	2.444394e-3
GO:0048743	positive regulation of skeletal muscle fiber development	2.458519e-3
GO:0014003	oligodendrocyte development	2.476231e-3
GO:0019083	viral transcription	2.488006e-3
GO:0071845	cellular component disassembly at cellular level	2.534414e-3
GO:2000026	regulation of multicellular organismal development	2.549968e-3
GO:0071398	cellular response to fatty acid	2.552127e-3
GO:0032274	gonadotropin secretion	2.647812e-3
GO:0051096	positive regulation of helicase activity	2.663626e-3
GO:0001704	formation of primary germ layer	2.721209e-3
GO:0009161	ribonucleoside monophosphate metabolic process	2.783111e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.818370e-3
GO:0006006	glucose metabolic process	2.820675e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.892646e-3
GO:0072111	cell proliferation involved in kidney development	2.920285e-3
GO:0009156	ribonucleoside monophosphate biosynthetic process	2.925510e-3
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.934032e-3
GO:0032066	nucleolus to nucleoplasm transport	2.934032e-3
GO:0045900	negative regulation of translational elongation	2.934032e-3
GO:0010720	positive regulation of cell development	2.987713e-3
GO:2000109	regulation of macrophage apoptosis	2.990402e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.029783e-3
GO:0050926	regulation of positive chemotaxis	3.038750e-3
GO:0007442	hindgut morphogenesis	3.076151e-3
GO:0022411	cellular component disassembly	3.144897e-3
GO:0031507	heterochromatin formation	3.179207e-3
GO:0042416	dopamine biosynthetic process	3.299813e-3
GO:0001894	tissue homeostasis	3.301354e-3
GO:0065001	specification of axis polarity	3.319274e-3
GO:0030644	cellular chloride ion homeostasis	3.319274e-3
GO:0006144	purine base metabolic process	3.330372e-3
GO:0071285	cellular response to lithium ion	3.330852e-3
GO:0090322	regulation of superoxide metabolic process	3.374041e-3
GO:0051318	G1 phase	3.376965e-3
GO:0010718	positive regulation of epithelial to mesenchymal transition	3.405241e-3
GO:0050793	regulation of developmental process	3.430950e-3
GO:0042074	cell migration involved in gastrulation	3.486404e-3
GO:0003406	retinal pigment epithelium development	3.493069e-3
GO:0060555	induction of necroptosis by extracellular signals	3.498841e-3
GO:0001763	morphogenesis of a branching structure	3.527335e-3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	3.573132e-3
GO:0045892	negative regulation of transcription, DNA-dependent	3.590116e-3
GO:0032148	activation of protein kinase B activity	3.683821e-3
GO:0006925	inflammatory cell apoptosis	3.684891e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	3.721832e-3
GO:0051252	regulation of RNA metabolic process	3.767289e-3
GO:0090273	regulation of somatostatin secretion	3.769708e-3
GO:0055119	relaxation of cardiac muscle	3.769708e-3
GO:0030219	megakaryocyte differentiation	3.769708e-3
GO:0090276	regulation of peptide hormone secretion	3.822260e-3
GO:0008078	mesodermal cell migration	3.877533e-3
GO:0018130	heterocycle biosynthetic process	3.913590e-3
GO:0006415	translational termination	3.952666e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	3.964552e-3
GO:0030258	lipid modification	3.983065e-3
GO:0006071	glycerol metabolic process	4.040402e-3
GO:0072321	chaperone-mediated protein transport	4.076875e-3
GO:0040009	regulation of growth rate	4.112934e-3
GO:0051939	gamma-aminobutyric acid import	4.182612e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	4.182612e-3
GO:0048871	multicellular organismal homeostasis	4.207583e-3
GO:0019058	viral infectious cycle	4.272234e-3
GO:0090343	positive regulation of cell aging	4.288431e-3
GO:0051896	regulation of protein kinase B signaling cascade	4.350883e-3
GO:0006885	regulation of pH	4.358537e-3
GO:0060323	head morphogenesis	4.401974e-3
GO:0007605	sensory perception of sound	4.419853e-3
GO:0016071	mRNA metabolic process	4.431439e-3
GO:0007411	axon guidance	4.561580e-3
GO:0019318	hexose metabolic process	4.580014e-3
GO:0021915	neural tube development	4.604407e-3
GO:0090003	regulation of establishment of protein localization in plasma membrane	4.640842e-3
GO:0090399	replicative senescence	4.684584e-3
GO:0019059	initiation of viral infection	4.711766e-3
GO:0031954	positive regulation of protein autophosphorylation	4.747048e-3
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	4.851085e-3
GO:0045746	negative regulation of Notch signaling pathway	4.862859e-3
GO:0045039	protein import into mitochondrial inner membrane	4.943364e-3
GO:0008625	induction of apoptosis via death domain receptors	4.944944e-3
GO:0072594	establishment of protein localization to organelle	4.974941e-3
GO:0010477	response to sulfur dioxide	4.989389e-3
GO:0002457	T cell antigen processing and presentation	4.989389e-3
GO:0055118	negative regulation of cardiac muscle contraction	5.021740e-3
GO:0051253	negative regulation of RNA metabolic process	5.157867e-3
GO:0051103	DNA ligation involved in DNA repair	5.177785e-3
GO:0002791	regulation of peptide secretion	5.241044e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	5.419527e-3
GO:0006366	transcription from RNA polymerase II promoter	5.495831e-3
GO:0042659	regulation of cell fate specification	5.511884e-3
GO:2000772	regulation of cellular senescence	5.576636e-3
GO:0051024	positive regulation of immunoglobulin secretion	5.746978e-3
GO:0043497	regulation of protein heterodimerization activity	5.812771e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	5.829736e-3
GO:0000073	spindle pole body separation	5.861633e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	5.925375e-3
GO:0070995	NADPH oxidation	5.940590e-3
GO:0034641	cellular nitrogen compound metabolic process	5.946478e-3
GO:0001958	endochondral ossification	6.070356e-3
GO:0051095	regulation of helicase activity	6.189674e-3
GO:0070972	protein localization in endoplasmic reticulum	6.333418e-3
GO:0006639	acylglycerol metabolic process	6.417692e-3
GO:0019227	neuronal action potential propagation	6.461684e-3
GO:0034284	response to monosaccharide stimulus	6.511795e-3
GO:0071346	cellular response to interferon-gamma	6.599815e-3
GO:0010717	regulation of epithelial to mesenchymal transition	6.628428e-3
GO:0043524	negative regulation of neuron apoptosis	6.723146e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	6.741498e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	6.777915e-3
GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	6.798107e-3
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	6.798107e-3
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	6.798107e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	6.798107e-3
GO:0034332	adherens junction organization	6.831915e-3
GO:2000278	regulation of DNA biosynthetic process	6.895185e-3
GO:0031327	negative regulation of cellular biosynthetic process	6.895757e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	6.921341e-3
GO:2000279	negative regulation of DNA biosynthetic process	6.968600e-3
GO:0009890	negative regulation of biosynthetic process	7.033962e-3
GO:0044249	cellular biosynthetic process	7.126368e-3
GO:0019400	alditol metabolic process	7.126678e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	7.170654e-3
GO:0048002	antigen processing and presentation of peptide antigen	7.258046e-3
GO:0042593	glucose homeostasis	7.340269e-3
GO:0072179	nephric duct formation	7.413169e-3
GO:0031325	positive regulation of cellular metabolic process	7.430493e-3
GO:0048522	positive regulation of cellular process	7.481413e-3
GO:0045923	positive regulation of fatty acid metabolic process	7.510124e-3
GO:0006369	termination of RNA polymerase II transcription	7.576394e-3
GO:0071777	positive regulation of cell cycle cytokinesis	7.642691e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	7.642691e-3
GO:0006214	thymidine catabolic process	7.701490e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	7.797590e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	7.865201e-3
GO:0048807	female genitalia morphogenesis	7.940626e-3
GO:0006919	activation of caspase activity	7.961382e-3
GO:0009084	glutamine family amino acid biosynthetic process	7.990738e-3
GO:0034623	cellular macromolecular complex disassembly	8.060292e-3
GO:0019369	arachidonic acid metabolic process	8.083589e-3
GO:0072164	mesonephric tubule development	8.083589e-3
GO:0035881	amacrine cell differentiation	8.184603e-3
GO:0001525	angiogenesis	8.219771e-3
GO:0035058	nonmotile primary cilium assembly	8.360825e-3
GO:0010604	positive regulation of macromolecule metabolic process	8.369151e-3
GO:0007155	cell adhesion	8.412869e-3
GO:0034260	negative regulation of GTPase activity	8.482331e-3
GO:0046849	bone remodeling	8.565743e-3
GO:0048598	embryonic morphogenesis	8.570392e-3
GO:0016051	carbohydrate biosynthetic process	8.659360e-3
GO:0045059	positive thymic T cell selection	8.686899e-3
GO:0034391	regulation of smooth muscle cell apoptosis	8.686899e-3
GO:0002456	T cell mediated immunity	8.686899e-3
GO:0006638	neutral lipid metabolic process	8.720764e-3
GO:0006641	triglyceride metabolic process	8.727361e-3
GO:0051607	defense response to virus	8.741570e-3
GO:0019433	triglyceride catabolic process	8.794762e-3
GO:0016337	cell-cell adhesion	8.798014e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	8.848224e-3
GO:0006355	regulation of transcription, DNA-dependent	9.064092e-3
GO:0060662	salivary gland cavitation	9.124355e-3
GO:0009112	nucleobase metabolic process	9.197385e-3
GO:0016571	histone methylation	9.234736e-3
GO:0007509	mesoderm migration involved in gastrulation	9.271747e-3
GO:0060684	epithelial-mesenchymal cell signaling	9.321771e-3
GO:0007172	signal complex assembly	9.321771e-3
GO:0051154	negative regulation of striated muscle cell differentiation	9.389184e-3
GO:0030282	bone mineralization	9.446386e-3
GO:0030262	apoptotic nuclear change	9.446386e-3
GO:0031497	chromatin assembly	9.450699e-3
GO:0009743	response to carbohydrate stimulus	9.453558e-3
GO:0090288	negative regulation of cellular response to growth factor stimulus	9.659252e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	9.739093e-3
GO:0006212	uracil catabolic process	9.739093e-3
GO:0006210	thymine catabolic process	9.739093e-3
GO:0014031	mesenchymal cell development	9.760884e-3
GO:0008380	RNA splicing	9.764143e-3
GO:0051149	positive regulation of muscle cell differentiation	9.918751e-3
GO:0034405	response to fluid shear stress	9.927888e-3
GO:0006569	tryptophan catabolic process	9.964021e-3
GO:0043017	positive regulation of lymphotoxin A biosynthetic process	9.980791e-3
GO:0010085	polarity specification of proximal/distal axis	9.980791e-3
GO:0048793	pronephros development	1.021530e-2
GO:0001955	blood vessel maturation	1.021530e-2
GO:0006568	tryptophan metabolic process	1.035776e-2
GO:0051186	cofactor metabolic process	1.055353e-2
GO:0001569	patterning of blood vessels	1.057845e-2
GO:0032984	macromolecular complex disassembly	1.065019e-2
GO:0002666	positive regulation of T cell tolerance induction	1.079288e-2
GO:2000191	regulation of fatty acid transport	1.082600e-2
GO:0031214	biomineral tissue development	1.087097e-2
GO:0006333	chromatin assembly or disassembly	1.117263e-2
GO:0006351	transcription, DNA-dependent	1.118439e-2
GO:0021629	olfactory nerve structural organization	1.145376e-2
GO:0046825	regulation of protein export from nucleus	1.164325e-2
GO:0090208	positive regulation of triglyceride metabolic process	1.170041e-2
GO:0010171	body morphogenesis	1.173215e-2
GO:0048754	branching morphogenesis of a tube	1.176726e-2
GO:0032713	negative regulation of interleukin-4 production	1.182510e-2
GO:0032890	regulation of organic acid transport	1.188886e-2
GO:0055098	response to low-density lipoprotein particle stimulus	1.193332e-2
GO:0006807	nitrogen compound metabolic process	1.200921e-2
GO:0034505	tooth mineralization	1.204634e-2
GO:0046635	positive regulation of alpha-beta T cell activation	1.223217e-2
GO:0048015	phosphatidylinositol-mediated signaling	1.224797e-2
GO:0046464	acylglycerol catabolic process	1.224904e-2
GO:0031175	neuron projection development	1.225276e-2
GO:0046341	CDP-diacylglycerol metabolic process	1.240181e-2
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	1.240181e-2
GO:0048643	positive regulation of skeletal muscle tissue development	1.246389e-2
GO:0009058	biosynthetic process	1.252760e-2
GO:0050848	regulation of calcium-mediated signaling	1.253382e-2
GO:0010660	regulation of muscle cell apoptosis	1.258341e-2
GO:0019859	thymine metabolic process	1.268719e-2
GO:0006625	protein targeting to peroxisome	1.272657e-2
GO:0010940	positive regulation of necrotic cell death	1.277611e-2
GO:0050870	positive regulation of T cell activation	1.319013e-2
GO:0006729	tetrahydrobiopterin biosynthetic process	1.321074e-2
GO:0060021	palate development	1.324442e-2
GO:0010629	negative regulation of gene expression	1.324485e-2
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.332576e-2
GO:0000904	cell morphogenesis involved in differentiation	1.348317e-2
GO:0006662	glycerol ether metabolic process	1.364105e-2
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.369862e-2
GO:0034645	cellular macromolecule biosynthetic process	1.371158e-2
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.378569e-2
GO:0002070	epithelial cell maturation	1.392490e-2
GO:0032933	SREBP-mediated signaling pathway	1.412955e-2
GO:0071396	cellular response to lipid	1.432543e-2
GO:0060466	activation of meiosis involved in egg activation	1.467441e-2
GO:0006284	base-excision repair	1.469609e-2
GO:0060795	cell fate commitment involved in formation of primary germ layers	1.477569e-2
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.487469e-2
GO:0032653	regulation of interleukin-10 production	1.488337e-2
GO:2000179	positive regulation of neural precursor cell proliferation	1.488337e-2
GO:0007409	axonogenesis	1.492691e-2
GO:0051171	regulation of nitrogen compound metabolic process	1.499691e-2
GO:0043574	peroxisomal transport	1.502115e-2
GO:2000344	positive regulation of acrosome reaction	1.504285e-2
GO:0042666	negative regulation of ectodermal cell fate specification	1.505147e-2
GO:0006145	purine base catabolic process	1.537362e-2
GO:0030838	positive regulation of actin filament polymerization	1.551728e-2
GO:0000723	telomere maintenance	1.562624e-2
GO:0050954	sensory perception of mechanical stimulus	1.573823e-2
GO:0048646	anatomical structure formation involved in morphogenesis	1.576559e-2
GO:0035814	negative regulation of renal sodium excretion	1.601591e-2
GO:0051153	regulation of striated muscle cell differentiation	1.614986e-2
GO:0046112	nucleobase biosynthetic process	1.626960e-2
GO:0051239	regulation of multicellular organismal process	1.629596e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.651690e-2
GO:0046887	positive regulation of hormone secretion	1.657059e-2
GO:0060986	endocrine hormone secretion	1.659255e-2
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	1.682757e-2
GO:0046104	thymidine metabolic process	1.682757e-2
GO:0006196	AMP catabolic process	1.682757e-2
GO:0046146	tetrahydrobiopterin metabolic process	1.702758e-2
GO:0009059	macromolecule biosynthetic process	1.717292e-2
GO:0048812	neuron projection morphogenesis	1.748192e-2
GO:2000369	regulation of clathrin-mediated endocytosis	1.758238e-2
GO:0001957	intramembranous ossification	1.770129e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	7.456868e-14
GO:0035912	dorsal aorta morphogenesis	1.215436e-11
GO:0030038	contractile actin filament bundle assembly	1.215436e-11
GO:0010735	positive regulation of transcription via serum response element binding	4.380530e-10
GO:0033561	regulation of water loss via skin	8.470993e-10
GO:0001947	heart looping	1.203516e-9
GO:0009952	anterior/posterior pattern specification	1.334835e-9
GO:0032367	intracellular cholesterol transport	1.494682e-9
GO:0009948	anterior/posterior axis specification	3.026831e-9
GO:0032078	negative regulation of endodeoxyribonuclease activity	3.903155e-9
GO:0006922	cleavage of lamin	3.903155e-9
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4.534695e-9
GO:0090009	primitive streak formation	5.326569e-9
GO:2000142	regulation of transcription initiation, DNA-dependent	5.861916e-9
GO:0032365	intracellular lipid transport	6.784613e-9
GO:0035050	embryonic heart tube development	7.486455e-9
GO:0016226	iron-sulfur cluster assembly	9.800665e-9
GO:0001704	formation of primary germ layer	1.100450e-8
GO:0042663	regulation of endodermal cell fate specification	1.188939e-8
GO:0007369	gastrulation	1.211287e-8
GO:0001711	endodermal cell fate commitment	2.584023e-8
GO:0001763	morphogenesis of a branching structure	2.760055e-8
GO:0055013	cardiac muscle cell development	4.282045e-8
GO:0010669	epithelial structure maintenance	4.423929e-8
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	5.763376e-8
GO:0060947	cardiac vascular smooth muscle cell differentiation	6.766397e-8
GO:0032074	negative regulation of nuclease activity	8.940276e-8
GO:0002541	activation of plasma proteins involved in acute inflammatory response	8.940276e-8
GO:0055006	cardiac cell development	8.984188e-8
GO:0003002	regionalization	1.030646e-7
GO:0048332	mesoderm morphogenesis	1.167761e-7
GO:0032071	regulation of endodeoxyribonuclease activity	1.291829e-7
GO:0035907	dorsal aorta development	1.480436e-7
GO:0060218	hemopoietic stem cell differentiation	1.704137e-7
GO:0035855	megakaryocyte development	1.955660e-7
GO:0035987	endodermal cell differentiation	2.037021e-7
GO:0055098	response to low-density lipoprotein particle stimulus	2.415538e-7
GO:0060795	cell fate commitment involved in formation of primary germ layers	3.024491e-7
GO:0032070	regulation of deoxyribonuclease activity	3.371409e-7
GO:2000121	regulation of removal of superoxide radicals	4.216744e-7
GO:0035909	aorta morphogenesis	4.928872e-7
GO:0007368	determination of left/right symmetry	5.124333e-7
GO:0035590	purinergic nucleotide receptor signaling pathway	5.157907e-7
GO:0048754	branching morphogenesis of a tube	5.684963e-7
GO:0039020	pronephric nephron tubule development	5.822482e-7
GO:0035565	regulation of pronephros size	5.822482e-7
GO:0009799	specification of symmetry	7.192697e-7
GO:0007569	cell aging	7.313373e-7
GO:0072181	mesonephric duct formation	7.485349e-7
GO:0035588	G-protein coupled purinergic receptor signaling pathway	8.742702e-7
GO:0007498	mesoderm development	8.760181e-7
GO:0035282	segmentation	9.114188e-7
GO:0009082	branched chain family amino acid biosynthetic process	1.575832e-6
GO:0021761	limbic system development	1.662136e-6
GO:0060931	sinoatrial node cell development	1.799973e-6
GO:0003167	atrioventricular bundle cell differentiation	1.799973e-6
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.032313e-6
GO:0002042	cell migration involved in sprouting angiogenesis	2.073489e-6
GO:0035904	aorta development	2.132876e-6
GO:0035886	vascular smooth muscle cell differentiation	2.427353e-6
GO:0007389	pattern specification process	2.539330e-6
GO:0055094	response to lipoprotein stimulus	2.721776e-6
GO:0008595	anterior/posterior axis specification, embryo	3.129874e-6
GO:0009798	axis specification	3.283485e-6
GO:0060921	sinoatrial node cell differentiation	3.756460e-6
GO:0007141	male meiosis I	3.827726e-6
GO:0021988	olfactory lobe development	3.939780e-6
GO:0070830	tight junction assembly	4.131266e-6
GO:0003151	outflow tract morphogenesis	4.296811e-6
GO:0038007	netrin-activated signaling pathway	4.551057e-6
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	4.551057e-6
GO:0035587	purinergic receptor signaling pathway	4.617211e-6
GO:0060932	His-Purkinje system cell differentiation	4.701455e-6
GO:0060926	pacemaker cell development	4.701455e-6
GO:0006437	tyrosyl-tRNA aminoacylation	5.101834e-6
GO:0055007	cardiac muscle cell differentiation	5.365698e-6
GO:0046884	follicle-stimulating hormone secretion	5.830981e-6
GO:0032275	luteinizing hormone secretion	5.830981e-6
GO:0061138	morphogenesis of a branching epithelium	5.998560e-6
GO:0061017	hepatoblast differentiation	6.273734e-6
GO:0048806	genitalia development	6.290556e-6
GO:0001714	endodermal cell fate specification	6.709423e-6
GO:0003163	sinoatrial node development	7.929345e-6
GO:0060920	pacemaker cell differentiation	8.751028e-6
GO:0060976	coronary vasculature development	1.058151e-5
GO:0001825	blastocyst formation	1.097593e-5
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.156461e-5
GO:0060537	muscle tissue development	1.339260e-5
GO:0090136	epithelial cell-cell adhesion	1.376939e-5
GO:0010159	specification of organ position	1.525093e-5
GO:0002011	morphogenesis of an epithelial sheet	1.584209e-5
GO:0021772	olfactory bulb development	1.719056e-5
GO:0042659	regulation of cell fate specification	1.731421e-5
GO:0048821	erythrocyte development	1.785087e-5
GO:0035564	regulation of kidney size	1.812565e-5
GO:0048646	anatomical structure formation involved in morphogenesis	1.829787e-5
GO:0007568	aging	2.130895e-5
GO:0090398	cellular senescence	2.299526e-5
GO:0060292	long term synaptic depression	2.309098e-5
GO:0050891	multicellular organismal water homeostasis	2.309098e-5
GO:0003206	cardiac chamber morphogenesis	2.338665e-5
GO:0048863	stem cell differentiation	2.399864e-5
GO:0003309	type B pancreatic cell differentiation	2.940986e-5
GO:0060923	cardiac muscle cell fate commitment	2.946050e-5
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	2.946050e-5
GO:0034625	fatty acid elongation, monounsaturated fatty acid	3.180702e-5
GO:0035239	tube morphogenesis	3.184453e-5
GO:0060347	heart trabecula formation	3.306541e-5
GO:0030219	megakaryocyte differentiation	3.306541e-5
GO:0048738	cardiac muscle tissue development	3.507606e-5
GO:0061384	heart trabecular morphogenesis	3.536587e-5
GO:0001826	inner cell mass cell differentiation	3.697719e-5
GO:2000379	positive regulation of reactive oxygen species metabolic process	3.884013e-5
GO:0031018	endocrine pancreas development	4.416399e-5
GO:0072180	mesonephric duct morphogenesis	4.536694e-5
GO:0001706	endoderm formation	4.808263e-5
GO:0001756	somitogenesis	5.895505e-5
GO:0043297	apical junction assembly	6.034684e-5
GO:0060907	positive regulation of macrophage cytokine production	6.047153e-5
GO:0010453	regulation of cell fate commitment	6.171004e-5
GO:0030539	male genitalia development	6.564406e-5
GO:0055003	cardiac myofibril assembly	6.614037e-5
GO:0090322	regulation of superoxide metabolic process	6.703153e-5
GO:0014706	striated muscle tissue development	7.111359e-5
GO:0003205	cardiac chamber development	7.545885e-5
GO:0003166	bundle of His development	7.842515e-5
GO:0072095	regulation of branch elongation involved in ureteric bud branching	7.956489e-5
GO:0060688	regulation of morphogenesis of a branching structure	8.117990e-5
GO:2000334	positive regulation of blood microparticle formation	8.123282e-5
GO:0046546	development of primary male sexual characteristics	8.124292e-5
GO:0055001	muscle cell development	8.160559e-5
GO:0001702	gastrulation with mouth forming second	8.385125e-5
GO:0007140	male meiosis	8.748924e-5
GO:0060444	branching involved in mammary gland duct morphogenesis	9.080849e-5
GO:0048729	tissue morphogenesis	9.203067e-5
GO:0060677	ureteric bud elongation	9.451684e-5
GO:0060411	cardiac septum morphogenesis	9.910317e-5
GO:0010470	regulation of gastrulation	9.949128e-5
GO:0045766	positive regulation of angiogenesis	1.164251e-4
GO:0019368	fatty acid elongation, unsaturated fatty acid	1.271282e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	1.359544e-4
GO:0021750	vestibular nucleus development	1.364581e-4
GO:0021679	cerebellar molecular layer development	1.364581e-4
GO:0021590	cerebellum maturation	1.364581e-4
GO:0046716	muscle cell homeostasis	1.387204e-4
GO:0060005	vestibular reflex	1.413587e-4
GO:0003350	pulmonary myocardium development	1.413587e-4
GO:0032908	regulation of transforming growth factor beta1 production	1.424204e-4
GO:0010817	regulation of hormone levels	1.429198e-4
GO:0000578	embryonic axis specification	1.437859e-4
GO:0007254	JNK cascade	1.509434e-4
GO:0032069	regulation of nuclease activity	1.525415e-4
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1.564798e-4
GO:0060911	cardiac cell fate commitment	1.591329e-4
GO:0045987	positive regulation of smooth muscle contraction	1.634124e-4
GO:0035051	cardiac cell differentiation	1.674160e-4
GO:0046879	hormone secretion	1.697281e-4
GO:0071447	cellular response to hydroperoxide	1.724149e-4
GO:0015911	plasma membrane long-chain fatty acid transport	1.724149e-4
GO:0072172	mesonephric tubule formation	1.769236e-4
GO:0009083	branched chain family amino acid catabolic process	1.773585e-4
GO:0001707	mesoderm formation	1.805781e-4
GO:0030220	platelet formation	1.857144e-4
GO:0023061	signal release	1.858800e-4
GO:0043000	Golgi to plasma membrane CFTR protein transport	1.893368e-4
GO:0050883	musculoskeletal movement, spinal reflex action	1.927455e-4
GO:0060414	aorta smooth muscle tissue morphogenesis	2.041703e-4
GO:0044283	small molecule biosynthetic process	2.149963e-4
GO:0035117	embryonic arm morphogenesis	2.187363e-4
GO:0060100	positive regulation of phagocytosis, engulfment	2.385024e-4
GO:0046661	male sex differentiation	2.531039e-4
GO:0046902	regulation of mitochondrial membrane permeability	2.574086e-4
GO:0010935	regulation of macrophage cytokine production	2.677487e-4
GO:0021766	hippocampus development	2.730154e-4
GO:0048793	pronephros development	2.862671e-4
GO:0043149	stress fiber assembly	2.894301e-4
GO:0021578	hindbrain maturation	2.915854e-4
GO:0051146	striated muscle cell differentiation	3.021660e-4
GO:0060841	venous blood vessel development	3.124989e-4
GO:2000108	positive regulation of leukocyte apoptosis	3.166517e-4
GO:0007492	endoderm development	3.252782e-4
GO:0042574	retinal metabolic process	3.253014e-4
GO:0030104	water homeostasis	3.370194e-4
GO:0032912	negative regulation of transforming growth factor beta2 production	3.526434e-4
GO:0071542	dopaminergic neuron differentiation	3.682345e-4
GO:0061053	somite development	3.708791e-4
GO:0042761	very long-chain fatty acid biosynthetic process	3.898456e-4
GO:0060004	reflex	3.976547e-4
GO:0031098	stress-activated protein kinase signaling cascade	4.053076e-4
GO:0016567	protein ubiquitination	4.137705e-4
GO:0009880	embryonic pattern specification	4.215681e-4
GO:0002009	morphogenesis of an epithelium	4.249162e-4
GO:0032755	positive regulation of interleukin-6 production	4.479652e-4
GO:0014056	regulation of acetylcholine secretion	4.606273e-4
GO:0072177	mesonephric duct development	4.667947e-4
GO:0051603	proteolysis involved in cellular protein catabolic process	4.691261e-4
GO:0040007	growth	4.760712e-4
GO:0072171	mesonephric tubule morphogenesis	5.229349e-4
GO:2000648	positive regulation of stem cell proliferation	5.295336e-4
GO:0008340	determination of adult lifespan	5.365048e-4
GO:0043503	skeletal muscle fiber adaptation	5.445243e-4
GO:0060638	mesenchymal-epithelial cell signaling	5.550655e-4
GO:0030239	myofibril assembly	5.650216e-4
GO:0072091	regulation of stem cell proliferation	5.741330e-4
GO:0002040	sprouting angiogenesis	5.843486e-4
GO:0060562	epithelial tube morphogenesis	5.932975e-4
GO:0003161	cardiac conduction system development	6.001152e-4
GO:0002779	antibacterial peptide secretion	6.244548e-4
GO:0050434	positive regulation of viral transcription	6.344752e-4
GO:0048852	diencephalon morphogenesis	6.502601e-4
GO:0060596	mammary placode formation	6.510766e-4
GO:0055096	low-density lipoprotein particle mediated signaling	6.899249e-4
GO:0031334	positive regulation of protein complex assembly	6.935047e-4
GO:0002720	positive regulation of cytokine production involved in immune response	7.002553e-4
GO:0030163	protein catabolic process	7.084560e-4
GO:0044257	cellular protein catabolic process	7.215050e-4
GO:0072179	nephric duct formation	7.219902e-4
GO:0061029	eyelid development in camera-type eye	7.226366e-4
GO:0001569	patterning of blood vessels	7.233250e-4
GO:0030497	fatty acid elongation	7.337280e-4
GO:0060788	ectodermal placode formation	8.068031e-4
GO:0006950	response to stress	8.407329e-4
GO:0060024	rhythmic synaptic transmission	8.608413e-4
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	8.829837e-4
GO:0031327	negative regulation of cellular biosynthetic process	8.904648e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	9.012802e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	9.012802e-4
GO:0000027	ribosomal large subunit assembly	9.317260e-4
GO:0016574	histone ubiquitination	9.470102e-4
GO:0045662	negative regulation of myoblast differentiation	9.857775e-4
GO:0070997	neuron death	9.857942e-4
GO:0060603	mammary gland duct morphogenesis	9.896460e-4
GO:0007493	endodermal cell fate determination	1.059591e-3
GO:0003279	cardiac septum development	1.078245e-3
GO:0009914	hormone transport	1.091276e-3
GO:0006633	fatty acid biosynthetic process	1.092542e-3
GO:0045165	cell fate commitment	1.097275e-3
GO:0009887	organ morphogenesis	1.127285e-3
GO:0006839	mitochondrial transport	1.205740e-3
GO:0071221	cellular response to bacterial lipopeptide	1.208698e-3
GO:0060437	lung growth	1.208698e-3
GO:0003148	outflow tract septum morphogenesis	1.231777e-3
GO:0061061	muscle structure development	1.277682e-3
GO:0007076	mitotic chromosome condensation	1.283194e-3
GO:0009890	negative regulation of biosynthetic process	1.305231e-3
GO:0003007	heart morphogenesis	1.317017e-3
GO:0007267	cell-cell signaling	1.336880e-3
GO:0031032	actomyosin structure organization	1.338147e-3
GO:0007548	sex differentiation	1.379690e-3
GO:0043534	blood vessel endothelial cell migration	1.395420e-3
GO:0046394	carboxylic acid biosynthetic process	1.407519e-3
GO:0048813	dendrite morphogenesis	1.422668e-3
GO:0051491	positive regulation of filopodium assembly	1.474569e-3
GO:0032446	protein modification by small protein conjugation	1.493250e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.579650e-3
GO:0033344	cholesterol efflux	1.617355e-3
GO:0009615	response to virus	1.643795e-3
GO:0050881	musculoskeletal movement	1.682389e-3
GO:0007043	cell-cell junction assembly	1.721314e-3
GO:0032911	negative regulation of transforming growth factor beta1 production	1.743270e-3
GO:0045785	positive regulation of cell adhesion	1.799646e-3
GO:0042472	inner ear morphogenesis	1.802327e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	1.803609e-3
GO:0007628	adult walking behavior	1.836024e-3
GO:0007006	mitochondrial membrane organization	1.836024e-3
GO:0014051	gamma-aminobutyric acid secretion	1.845981e-3
GO:0032274	gonadotropin secretion	1.894233e-3
GO:0051145	smooth muscle cell differentiation	1.938684e-3
GO:0051253	negative regulation of RNA metabolic process	2.012181e-3
GO:0061383	trabecula morphogenesis	2.052347e-3
GO:0051025	negative regulation of immunoglobulin secretion	2.200880e-3
GO:0009081	branched chain family amino acid metabolic process	2.210235e-3
GO:0045022	early endosome to late endosome transport	2.284612e-3
GO:0001829	trophectodermal cell differentiation	2.301505e-3
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.303562e-3
GO:0017004	cytochrome complex assembly	2.303562e-3
GO:0010811	positive regulation of cell-substrate adhesion	2.362818e-3
GO:0051354	negative regulation of oxidoreductase activity	2.373020e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.422924e-3
GO:0042060	wound healing	2.505087e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	2.511615e-3
GO:0030644	cellular chloride ion homeostasis	2.551568e-3
GO:0072078	nephron tubule morphogenesis	2.602224e-3
GO:0072178	nephric duct morphogenesis	2.653154e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	2.654499e-3
GO:0030301	cholesterol transport	2.658042e-3
GO:0030193	regulation of blood coagulation	2.721332e-3
GO:0046782	regulation of viral transcription	2.730612e-3
GO:0035295	tube development	2.743105e-3
GO:0006511	ubiquitin-dependent protein catabolic process	2.749917e-3
GO:0030534	adult behavior	2.786536e-3
GO:0060412	ventricular septum morphogenesis	2.812108e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	2.812964e-3
GO:0045995	regulation of embryonic development	2.857834e-3
GO:0019835	cytolysis	2.877102e-3
GO:0009791	post-embryonic development	2.930505e-3
GO:0030194	positive regulation of blood coagulation	2.932236e-3
GO:0031175	neuron projection development	2.946790e-3
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	2.961658e-3
GO:0060210	metestrus	2.961658e-3
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.961658e-3
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	2.961658e-3
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	2.961658e-3
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	2.961658e-3
GO:0042904	9-cis-retinoic acid biosynthetic process	2.965476e-3
GO:0051402	neuron apoptosis	3.009044e-3
GO:0071634	regulation of transforming growth factor beta production	3.072849e-3
GO:0051188	cofactor biosynthetic process	3.110908e-3
GO:0070245	positive regulation of thymocyte apoptosis	3.129697e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	3.204032e-3
GO:0071402	cellular response to lipoprotein particle stimulus	3.265526e-3
GO:0071223	cellular response to lipoteichoic acid	3.265526e-3
GO:0032909	regulation of transforming growth factor beta2 production	3.284077e-3
GO:0021952	central nervous system projection neuron axonogenesis	3.293357e-3
GO:0019941	modification-dependent protein catabolic process	3.303998e-3
GO:0060343	trabecula formation	3.325544e-3
GO:0043254	regulation of protein complex assembly	3.366117e-3
GO:0021543	pallium development	3.404593e-3
GO:0048145	regulation of fibroblast proliferation	3.422845e-3
GO:0030320	cellular monovalent inorganic anion homeostasis	3.423021e-3
GO:0043632	modification-dependent macromolecule catabolic process	3.425555e-3
GO:0061041	regulation of wound healing	3.456923e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	3.488849e-3
GO:0045059	positive thymic T cell selection	3.525728e-3
GO:0000209	protein polyubiquitination	3.537301e-3
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	3.585600e-3
GO:0032353	negative regulation of hormone biosynthetic process	3.585600e-3
GO:0070234	positive regulation of T cell apoptosis	3.684041e-3
GO:0007616	long-term memory	3.687432e-3
GO:0070848	response to growth factor stimulus	3.722375e-3
GO:0060067	cervix development	3.724398e-3
GO:0045892	negative regulation of transcription, DNA-dependent	3.786216e-3
GO:0010498	proteasomal protein catabolic process	3.864483e-3
GO:0072176	nephric duct development	3.886865e-3
GO:0022603	regulation of anatomical structure morphogenesis	3.923395e-3
GO:0051489	regulation of filopodium assembly	3.940473e-3
GO:0006104	succinyl-CoA metabolic process	3.971447e-3
GO:0002826	negative regulation of T-helper 1 type immune response	3.971447e-3
GO:2000377	regulation of reactive oxygen species metabolic process	4.040208e-3
GO:0043524	negative regulation of neuron apoptosis	4.048390e-3
GO:0015812	gamma-aminobutyric acid transport	4.104603e-3
GO:0007005	mitochondrion organization	4.179569e-3
GO:0048598	embryonic morphogenesis	4.234224e-3
GO:0060415	muscle tissue morphogenesis	4.272688e-3
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	4.293392e-3
GO:0045040	protein import into mitochondrial outer membrane	4.293392e-3
GO:0002553	histamine secretion by mast cell	4.293392e-3
GO:0002741	positive regulation of cytokine secretion involved in immune response	4.293392e-3
GO:0048147	negative regulation of fibroblast proliferation	4.308075e-3
GO:0045933	positive regulation of muscle contraction	4.581965e-3
GO:0071635	negative regulation of transforming growth factor beta production	4.672086e-3
GO:0031324	negative regulation of cellular metabolic process	4.690840e-3
GO:0072164	mesonephric tubule development	4.709971e-3
GO:0055002	striated muscle cell development	4.719256e-3
GO:0001824	blastocyst development	4.784493e-3
GO:0007257	activation of JUN kinase activity	4.801491e-3
GO:0060743	epithelial cell maturation involved in prostate gland development	4.912288e-3
GO:0045014	negative regulation of transcription by glucose	4.912288e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	4.962727e-3
GO:0048853	forebrain morphogenesis	5.009872e-3
GO:0030240	skeletal muscle thin filament assembly	5.009872e-3
GO:0048644	muscle organ morphogenesis	5.023643e-3
GO:0033554	cellular response to stress	5.082496e-3
GO:0030073	insulin secretion	5.219299e-3
GO:0002790	peptide secretion	5.345108e-3
GO:0009607	response to biotic stimulus	5.371506e-3
GO:0060560	developmental growth involved in morphogenesis	5.397675e-3
GO:0032472	Golgi calcium ion transport	5.418276e-3
GO:0032468	Golgi calcium ion homeostasis	5.418276e-3
GO:0030026	cellular manganese ion homeostasis	5.418276e-3
GO:0007032	endosome organization	5.516625e-3
GO:0043589	skin morphogenesis	5.518779e-3
GO:0042471	ear morphogenesis	5.567771e-3
GO:0048850	hypophysis morphogenesis	5.582263e-3
GO:0030540	female genitalia development	5.649790e-3
GO:0045765	regulation of angiogenesis	5.653860e-3
GO:0042362	fat-soluble vitamin biosynthetic process	5.960337e-3
GO:0030825	positive regulation of cGMP metabolic process	5.960337e-3
GO:0050820	positive regulation of coagulation	6.218460e-3
GO:0048468	cell development	6.257316e-3
GO:0034261	negative regulation of Ras GTPase activity	6.304399e-3
GO:0043032	positive regulation of macrophage activation	6.345309e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	6.379581e-3
GO:0071158	positive regulation of cell cycle arrest	6.465751e-3
GO:0070232	regulation of T cell apoptosis	6.465751e-3
GO:0045214	sarcomere organization	6.483410e-3
GO:0030155	regulation of cell adhesion	6.581788e-3
GO:0048524	positive regulation of viral reproduction	6.651513e-3
GO:0060751	branch elongation involved in mammary gland duct branching	6.684869e-3
GO:0045216	cell-cell junction organization	6.745910e-3
GO:0044265	cellular macromolecule catabolic process	6.755355e-3
GO:0050818	regulation of coagulation	6.865289e-3
GO:0060592	mammary gland formation	6.955954e-3
GO:0021889	olfactory bulb interneuron differentiation	6.955954e-3
GO:0035695	mitochondrion degradation by induced vacuole formation	7.070043e-3
GO:0002309	T cell proliferation involved in immune response	7.079682e-3
GO:0046463	acylglycerol biosynthetic process	7.098739e-3
GO:0044249	cellular biosynthetic process	7.230463e-3
GO:0055088	lipid homeostasis	7.264506e-3
GO:0045137	development of primary sexual characteristics	7.354459e-3
GO:0034599	cellular response to oxidative stress	7.422480e-3
GO:0048844	artery morphogenesis	7.442002e-3
GO:0003310	pancreatic A cell differentiation	7.465399e-3
GO:0090403	oxidative stress-induced premature senescence	7.487539e-3
GO:0022029	telencephalon cell migration	7.639790e-3
GO:0060548	negative regulation of cell death	7.700471e-3
GO:0033630	positive regulation of cell adhesion mediated by integrin	7.738316e-3
GO:0051707	response to other organism	7.805481e-3
GO:2000484	positive regulation of interleukin-8 secretion	7.909014e-3
GO:0003344	pericardium morphogenesis	7.909014e-3
GO:0060986	endocrine hormone secretion	7.939945e-3
GO:0019244	lactate biosynthetic process from pyruvate	7.969741e-3
GO:0021990	neural plate formation	7.969741e-3
GO:0002003	angiotensin maturation	7.970630e-3
GO:0000415	negative regulation of histone H3-K36 methylation	7.970630e-3
GO:0048589	developmental growth	8.002433e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	8.017707e-3
GO:0021548	pons development	8.017707e-3
GO:0001568	blood vessel development	8.113337e-3
GO:0031398	positive regulation of protein ubiquitination	8.200551e-3
GO:0030168	platelet activation	8.230687e-3
GO:0007263	nitric oxide mediated signal transduction	8.303632e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	8.344205e-3
GO:0060840	artery development	8.359276e-3
GO:0009110	vitamin biosynthetic process	8.467755e-3
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	8.559853e-3
GO:0042573	retinoic acid metabolic process	8.563678e-3
GO:2000106	regulation of leukocyte apoptosis	8.792881e-3
GO:0010458	exit from mitosis	8.793207e-3
GO:0000733	DNA strand renaturation	8.793207e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	8.907396e-3
GO:0060575	intestinal epithelial cell differentiation	9.017852e-3
GO:0021537	telencephalon development	9.040620e-3
GO:0048752	semicircular canal morphogenesis	9.488366e-3
GO:0090037	positive regulation of protein kinase C signaling cascade	9.732993e-3
GO:0021885	forebrain cell migration	9.748911e-3
GO:0035115	embryonic forelimb morphogenesis	9.773283e-3
GO:0000038	very long-chain fatty acid metabolic process	9.861400e-3
GO:0046504	glycerol ether biosynthetic process	9.975492e-3
GO:0042221	response to chemical stimulus	1.005234e-2
GO:0010927	cellular component assembly involved in morphogenesis	1.005520e-2
GO:0048286	lung alveolus development	1.021931e-2
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.022394e-2
GO:0051890	regulation of cardioblast differentiation	1.022537e-2
GO:0014866	skeletal myofibril assembly	1.047950e-2
GO:0007127	meiosis I	1.078164e-2
GO:0042992	negative regulation of transcription factor import into nucleus	1.083186e-2
GO:0070171	negative regulation of tooth mineralization	1.096113e-2
GO:0044268	multicellular organismal protein metabolic process	1.096113e-2
GO:0007420	brain development	1.100590e-2
GO:0070243	regulation of thymocyte apoptosis	1.104790e-2
GO:0051930	regulation of sensory perception of pain	1.126773e-2
GO:0010820	positive regulation of T cell chemotaxis	1.153486e-2
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.171425e-2
GO:0043069	negative regulation of programmed cell death	1.175071e-2
GO:0046015	regulation of transcription by glucose	1.178188e-2
GO:0008333	endosome to lysosome transport	1.181507e-2
GO:2000406	positive regulation of T cell migration	1.189637e-2
GO:0021930	cerebellar granule cell precursor proliferation	1.205147e-2
GO:0032675	regulation of interleukin-6 production	1.222401e-2
GO:0043542	endothelial cell migration	1.229630e-2
GO:0043066	negative regulation of apoptosis	1.230852e-2
GO:0045658	regulation of neutrophil differentiation	1.232977e-2
GO:0050805	negative regulation of synaptic transmission	1.256614e-2
GO:0030857	negative regulation of epithelial cell differentiation	1.264608e-2
GO:0001894	tissue homeostasis	1.267683e-2
GO:0043506	regulation of JUN kinase activity	1.268709e-2
GO:0022612	gland morphogenesis	1.270489e-2
GO:0001954	positive regulation of cell-matrix adhesion	1.288693e-2
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	1.302420e-2
GO:0043501	skeletal muscle adaptation	1.302420e-2
GO:0009058	biosynthetic process	1.310365e-2
GO:0035249	synaptic transmission, glutamatergic	1.313096e-2
GO:0060443	mammary gland morphogenesis	1.326044e-2
GO:0072079	nephron tubule formation	1.326175e-2
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.326175e-2
GO:0001938	positive regulation of endothelial cell proliferation	1.330045e-2
GO:0006952	defense response	1.330218e-2
GO:0070170	regulation of tooth mineralization	1.346877e-2
GO:0003323	type B pancreatic cell development	1.346877e-2
GO:0007034	vacuolar transport	1.373891e-2
GO:0060425	lung morphogenesis	1.394735e-2
GO:0060686	negative regulation of prostatic bud formation	1.405998e-2
GO:0002483	antigen processing and presentation of endogenous peptide antigen	1.405998e-2
GO:0072028	nephron morphogenesis	1.406562e-2
GO:0043405	regulation of MAP kinase activity	1.406944e-2
GO:0019432	triglyceride biosynthetic process	1.421794e-2
GO:0021986	habenula development	1.436760e-2
GO:0000414	regulation of histone H3-K36 methylation	1.436760e-2
GO:0006626	protein targeting to mitochondrion	1.439977e-2
GO:0007596	blood coagulation	1.445613e-2
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	1.450165e-2
GO:0007417	central nervous system development	1.462013e-2
GO:0051964	negative regulation of synapse assembly	1.466572e-2
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	1.467586e-2
GO:0070647	protein modification by small protein conjugation or removal	1.479806e-2
GO:0007599	hemostasis	1.521937e-2
GO:0034260	negative regulation of GTPase activity	1.528603e-2
GO:0006379	mRNA cleavage	1.528603e-2
GO:0010259	multicellular organismal aging	1.548104e-2