UBERON:0002148: Difference between revisions
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|located_in= | |located_in= | ||
|name=locus ceruleus | |name=locus ceruleus | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0003023 | |part_of=UBERON:0003023 | ||
Latest revision as of 17:27, 12 September 2014
| Name: | locus ceruleus | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." [GAID:577, GO:0021703, Wikipedia:Locus_ceruleus] | ||
| Xrefs: |
| ||
| Synonyms: |
"blue nucleus" EXACT [NIF_GrossAnatomy:birnlex_905] "caerulean nucleus" EXACT [] "locus caeruleus" EXACT [NIF_GrossAnatomy:birnlex_905] "locus cinereus" RELATED [BTO:0001408] "locus coeruleu" EXACT [] "locus coeruleus" EXACT [] "nucleus caeruleus" EXACT [FMA:72478, FMA:TA] "nucleus of locus caeruleus" EXACT [] "nucleus pigmentosus pontis" EXACT [NIF_GrossAnatomy:birnlex_905] "substantia ferruginea" EXACT [NIF_GrossAnatomy:birnlex_905] | ||
| Comments: | TODO - check ZFA/pons. also GO says part of dorsorostral pons | ||
| Alt_id: | UBERON:FMA_72478-MA_0001017-ZFA_0000539 | ||
| Subset: |
uberon_slim vertebrate_core |
200px-Gray709.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0006331(brainstem nucleus),UBERON:0009662(hindbrain nucleus) |
|---|---|
| part_of: | UBERON:0003023(pontine tegmentum) |
Children
| is a: | FF:10362-105F2 (locus coeruleus, newborn, donor10223) |
|---|---|
| derives from: | FF:0011487 (human locus coeruleus- adult sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10165-103B3 (locus coeruleus, adult, donor10252)
- 10182-103D2 (locus coeruleus - adult, donor10196)
- 10362-105F2 (locus coeruleus, newborn, donor10223)
- 10375-105G6 (locus coeruleus, adult, donor10258)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002148 (locus ceruleus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 3.29e-195 | FFCP PHASE1:Hg19::chr2:237146889..237146895,-#_3d8b1683908909bb5c96d7128eaafc12 | p@chr2:237146889..237146895, - |
| 3.29e-195 | FFCP PHASE2:Hg19::chr2:237146889..237146895,-#_3d8b1683908909bb5c96d7128eaafc12 | p@chr2:237146889..237146895, - |
| 4.22e-98 | FFCP PHASE1:Hg19::chr16:49601912..49601949,-#_db86f2cb1a96bb56e633f22bc7b91265 | p@chr16:49601912..49601949, - |
| 4.22e-98 | FFCP PHASE2:Hg19::chr16:49601912..49601949,-#_db86f2cb1a96bb56e633f22bc7b91265 | p@chr16:49601912..49601949, - |
| 1.16e-78 | FFCP PHASE1:Hg19::chr2:108602711..108602722,+#_5cfb487dc97ea73eaed3f5dab587e0b3 | p3@SLC5A7 |
| 1.16e-78 | FFCP PHASE2:Hg19::chr2:108602711..108602722,+#_5cfb487dc97ea73eaed3f5dab587e0b3 | p3@SLC5A7 |
| 2.84e-66 | FFCP PHASE2:Hg19::chr17:7559346..7559354,+#_cf05b1af1b1b4be6cf78f45dd7793749 | p@chr17:7559346..7559354, + |
| 2.84e-66 | FFCP PHASE1:Hg19::chr17:7559346..7559354,+#_cf05b1af1b1b4be6cf78f45dd7793749 | p@chr17:7559346..7559354, + |
| 3.58e-57 | FFCP PHASE1:Hg19::chr2:234077664..234077672,+#_0284385191acdfa85c84706163956e91 | p@chr2:234077664..234077672, + |
| 3.58e-57 | FFCP PHASE2:Hg19::chr2:234077664..234077672,+#_0284385191acdfa85c84706163956e91 | p@chr2:234077664..234077672, + |
| 6.36e-57 | FFCP PHASE2:Hg19::chr9:87427873..87427884,+#_ac6a7447c13c77f9d47596e37c127659 | p67@NTRK2 |
| 6.36e-57 | FFCP PHASE1:Hg19::chr9:87427873..87427884,+#_ac6a7447c13c77f9d47596e37c127659 | p67@NTRK2 |
| 8.47e-57 | FFCP PHASE1:Hg19::chr11:30751827..30751838,+#_0d825f42857458efbe964527bd6cee77 | p@chr11:30751827..30751838, + |
| 8.47e-57 | FFCP PHASE2:Hg19::chr11:30751827..30751838,+#_0d825f42857458efbe964527bd6cee77 | p@chr11:30751827..30751838, + |
| 8.47e-57 | FFCP PHASE2:Hg19::chr5:75379091..75379100,+#_0d825f42857458efbe964527bd6cee77 | p6@SV2C |
| 8.47e-57 | FFCP PHASE1:Hg19::chr5:75379091..75379100,+#_0d825f42857458efbe964527bd6cee77 | p6@SV2C |
| 1.13e-56 | FFCP PHASE1:Hg19::chr4:117675601..117675614,+#_d69cf710999970f6c66b5c01219803a1 | p@chr4:117675601..117675614, + |
| 1.13e-56 | FFCP PHASE2:Hg19::chr4:117675601..117675614,+#_d69cf710999970f6c66b5c01219803a1 | p@chr4:117675601..117675614, + |
| 1.5e-56 | FFCP PHASE1:Hg19::chr9:135089670..135089681,-#_50ec54165d4393a3d4f86b403e2ce298 | p@chr9:135089670..135089681, - |
| 1.5e-56 | FFCP PHASE2:Hg19::chr10:133878269..133878278,+#_50ec54165d4393a3d4f86b403e2ce298 | p@chr10:133878269..133878278, + |
| 1.5e-56 | FFCP PHASE2:Hg19::chr9:135089670..135089681,-#_50ec54165d4393a3d4f86b403e2ce298 | p@chr9:135089670..135089681, - |
| 1.5e-56 | FFCP PHASE1:Hg19::chr10:133878269..133878278,+#_50ec54165d4393a3d4f86b403e2ce298 | p@chr10:133878269..133878278, + |
| 2.0e-56 | FFCP PHASE2:Hg19::chr7:94297970..94297982,+#_a9b6497ab975a4080818d825a3a530c4 | p@chr7:94297970..94297982, + |
| 2.0e-56 | FFCP PHASE1:Hg19::chr7:94297970..94297982,+#_a9b6497ab975a4080818d825a3a530c4 | p@chr7:94297970..94297982, + |
| 1.46e-50 | FFCP PHASE2:Hg19::chr5:71505323..71505333,+#_9f8ed49c2029a57e1a1359966c9c355c | p@chr5:71505323..71505333, + |
| 1.46e-50 | FFCP PHASE1:Hg19::chr5:71505323..71505333,+#_9f8ed49c2029a57e1a1359966c9c355c | p@chr5:71505323..71505333, + |
| 1.88e-50 | FFCP PHASE1:Hg19::chr18:5577640..5577652,-#_9a9853cd63769d497647b0dd91c68668 | p14@EPB41L3 |
| 1.88e-50 | FFCP PHASE2:Hg19::chr18:5577640..5577652,-#_9a9853cd63769d497647b0dd91c68668 | p14@EPB41L3 |
| 2.74e-50 | FFCP PHASE2:Hg19::chr11:20621167..20621170,+#_18dd88540353a6cae4d6954231981097 | p6@SLC6A5 |
| 2.74e-50 | FFCP PHASE1:Hg19::chr4:114303795..114303800,+#_18dd88540353a6cae4d6954231981097 | p51@ANK2 |
| 2.74e-50 | FFCP PHASE1:Hg19::chr11:20621167..20621170,+#_18dd88540353a6cae4d6954231981097 | p6@SLC6A5 |
| 2.74e-50 | FFCP PHASE2:Hg19::chr4:114303795..114303800,+#_18dd88540353a6cae4d6954231981097 | p51@ANK2 |
| 4.0e-50 | FFCP PHASE2:Hg19::chr22:37213554..37213565,-#_d4e94024d70e649ceec4b8cb54a352af | p4@PVALB |
| 4.0e-50 | FFCP PHASE1:Hg19::chr22:37213554..37213565,-#_d4e94024d70e649ceec4b8cb54a352af | p4@PVALB |
| 4.52e-50 | FFCP PHASE2:Hg19::chr6:56820018..56820029,+#_cdfc6057e90243fb00fe5f41ad1e316a | p16@BEND6 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr2:218873244..218873256,-#_cdfc6057e90243fb00fe5f41ad1e316a | p@chr2:218873244..218873256, - |
| 4.52e-50 | FFCP PHASE2:Hg19::chr2:218873244..218873256,-#_cdfc6057e90243fb00fe5f41ad1e316a | p@chr2:218873244..218873256, - |
| 4.52e-50 | FFCP PHASE1:Hg19::chr6:56820018..56820029,+#_cdfc6057e90243fb00fe5f41ad1e316a | p16@BEND6 |
| 5.15e-50 | FFCP PHASE1:Hg19::chr3:183979132..183979143,-#_47cf2de29319ca7128c9d30101cadb82 | p8@CAMK2N2 |
| 5.15e-50 | FFCP PHASE2:Hg19::chr3:183979132..183979143,-#_47cf2de29319ca7128c9d30101cadb82 | p8@CAMK2N2 |
| 6.61e-50 | FFCP PHASE2:Hg19::chr11:81982984..81982991,+#_36e4bc5c54a633773e58ff0cd116e0bc | p@chr11:81982984..81982991, + |
| 6.61e-50 | FFCP PHASE1:Hg19::chr11:81982984..81982991,+#_36e4bc5c54a633773e58ff0cd116e0bc | p@chr11:81982984..81982991, + |
| 6.61e-50 | FFCP PHASE2:Hg19::chr8:82354790..82354800,-#_36e4bc5c54a633773e58ff0cd116e0bc | p@chr8:82354790..82354800, - |
| 6.61e-50 | FFCP PHASE1:Hg19::chr8:82354790..82354800,-#_36e4bc5c54a633773e58ff0cd116e0bc | p@chr8:82354790..82354800, - |
| 6.61e-50 | FFCP PHASE1:Hg19::chr22:26565113..26565124,+#_36e4bc5c54a633773e58ff0cd116e0bc | p7@SEZ6L |
| 6.61e-50 | FFCP PHASE2:Hg19::chr22:26565113..26565124,+#_36e4bc5c54a633773e58ff0cd116e0bc | p7@SEZ6L |
| 8.5e-50 | FFCP PHASE1:Hg19::chr1:160113171..160113182,+#_60c63187bf07fee3df102cd3506918ac | p@chr1:160113171..160113182, + |
| 8.5e-50 | FFCP PHASE2:Hg19::chr1:160113171..160113182,+#_60c63187bf07fee3df102cd3506918ac | p@chr1:160113171..160113182, + |
| 1.4e-49 | FFCP PHASE2:Hg19::chr6:55039307..55039326,+#_7799de21633b1ae17d729a5393397391 | p1@HCRTR2 |
| 1.4e-49 | FFCP PHASE1:Hg19::chr6:55039307..55039326,+#_7799de21633b1ae17d729a5393397391 | p1@HCRTR2 |
| 1.8e-49 | FFCP PHASE2:Hg19::chr8:23127683..23127694,+#_109181f582bf2385abfdc68742e0a480 | p8@R3HCC1 |
| 1.8e-49 | FFCP PHASE1:Hg19::chr8:23127683..23127694,+#_109181f582bf2385abfdc68742e0a480 | p8@R3HCC1 |
| 3.19e-45 | FFCP PHASE2:Hg19::chr15:60296481..60296492,+#_de7582d09019595f426068d0774d08f8 | p7@FOXB1 |
| 3.19e-45 | FFCP PHASE1:Hg19::chr15:60296481..60296492,+#_de7582d09019595f426068d0774d08f8 | p7@FOXB1 |
| 5.0e-45 | FFCP PHASE1:Hg19::chr3:58372039..58372043,+#_cdaa1235671df331a858d86a88f21302 | p@chr3:58372039..58372043, + |
| 5.0e-45 | FFCP PHASE2:Hg19::chr3:58372039..58372043,+#_cdaa1235671df331a858d86a88f21302 | p@chr3:58372039..58372043, + |
| 7.83e-45 | FFCP PHASE1:Hg19::chr1:160112787..160112798,+#_f5567ccb61b6fce43a8b8238a2647b32 | p12@ATP1A2 |
| 7.83e-45 | FFCP PHASE2:Hg19::chr1:160112787..160112798,+#_f5567ccb61b6fce43a8b8238a2647b32 | p12@ATP1A2 |
| 9.79e-45 | FFCP PHASE1:Hg19::chr8:28748765..28748785,+#_51226ae0fa555d20f1cd01ae2cd61c0c | p10@HMBOX1 |
| 9.79e-45 | FFCP PHASE1:Hg19::chr22:29885906..29885916,+#_51226ae0fa555d20f1cd01ae2cd61c0c | p@chr22:29885906..29885916, + |
| 9.79e-45 | FFCP PHASE2:Hg19::chr22:29885906..29885916,+#_51226ae0fa555d20f1cd01ae2cd61c0c | p@chr22:29885906..29885916, + |
| 9.79e-45 | FFCP PHASE2:Hg19::chr8:28748765..28748785,+#_51226ae0fa555d20f1cd01ae2cd61c0c | p10@HMBOX1 |
| 2.39e-44 | FFCP PHASE2:Hg19::chr18:74691000..74691005,-#_6db22ee563bd769922d90d23c2401e70 | p@chr18:74691000..74691005, - |
| 2.39e-44 | FFCP PHASE2:Hg19::chr17:42983463..42983466,-#_6db22ee563bd769922d90d23c2401e70 | p45@GFAP |
| 2.39e-44 | FFCP PHASE1:Hg19::chr18:74691000..74691005,-#_6db22ee563bd769922d90d23c2401e70 | p@chr18:74691000..74691005, - |
| 2.39e-44 | FFCP PHASE1:Hg19::chr17:42983463..42983466,-#_6db22ee563bd769922d90d23c2401e70 | p45@GFAP |
| 2.98e-44 | FFCP PHASE2:Hg19::chr7:12544061..12544073,+#_6dc935613ba7df6b985ac500d9afa61b | p1@ENST00000424453 |
| 2.98e-44 | FFCP PHASE1:Hg19::chr7:12544061..12544073,+#_6dc935613ba7df6b985ac500d9afa61b | p1@ENST00000424453 |
| 3.72e-44 | FFCP PHASE2:Hg19::chr13:70682590..70682601,-#_43a4a94ee0570742248abd9eed5706e9 | p3@KLHL1 |
| 3.72e-44 | FFCP PHASE1:Hg19::chr13:70682590..70682601,-#_43a4a94ee0570742248abd9eed5706e9 | p3@KLHL1 |
| 4.65e-44 | FFCP PHASE2:Hg19::chr8:81639875..81639889,-#_29fb75c7cd408ce76bde5d637374baa4 | p@chr8:81639875..81639889, - |
| 4.65e-44 | FFCP PHASE1:Hg19::chr8:81639875..81639889,-#_29fb75c7cd408ce76bde5d637374baa4 | p@chr8:81639875..81639889, - |
| 4.89e-41 | FFCP PHASE2:Hg19::chr12:72332618..72332632,+#_ee18646db8aa96d3b4c4eb4202febd37 | p1@TPH2 |
| 4.89e-41 | FFCP PHASE1:Hg19::chr12:72332618..72332632,+#_ee18646db8aa96d3b4c4eb4202febd37 | p1@TPH2 |
| 1.34e-40 | FFCP PHASE2:Hg19::chr14:62010202..62010207,-#_39c8a0ec234dcd6133d4838f4cd2b478 | p@chr14:62010202..62010207, - |
| 1.34e-40 | FFCP PHASE1:Hg19::chr14:62010202..62010207,-#_39c8a0ec234dcd6133d4838f4cd2b478 | p@chr14:62010202..62010207, - |
| 1.64e-40 | FFCP PHASE2:Hg19::chr8:24775490..24775500,+#_4a490c88fbc1ee3b5e6a45232a44fcd7 | p@chr8:24775490..24775500, + |
| 1.64e-40 | FFCP PHASE1:Hg19::chr8:24775490..24775500,+#_4a490c88fbc1ee3b5e6a45232a44fcd7 | p@chr8:24775490..24775500, + |
| 2.01e-40 | FFCP PHASE2:Hg19::chr4:67195068..67195099,-#_805112659dded9d1af7af3008b5a5c40 | p@chr4:67195068..67195099, - |
| 2.01e-40 | FFCP PHASE1:Hg19::chr4:67195068..67195099,-#_805112659dded9d1af7af3008b5a5c40 | p@chr4:67195068..67195099, - |
| 2.46e-40 | FFCP PHASE1:Hg19::chr19:35789028..35789044,+#_47c9b69f9dbb4ea60409f7d19b064cbb | p@chr19:35789028..35789044, + |
| 2.46e-40 | FFCP PHASE2:Hg19::chr19:35789028..35789044,+#_47c9b69f9dbb4ea60409f7d19b064cbb | p@chr19:35789028..35789044, + |
| 2.46e-40 | FFCP PHASE1:Hg19::chr1:155291376..155291428,+#_47c9b69f9dbb4ea60409f7d19b064cbb | p6@RUSC1 |
| 2.46e-40 | FFCP PHASE2:Hg19::chr1:155291376..155291428,+#_47c9b69f9dbb4ea60409f7d19b064cbb | p6@RUSC1 |
| 3.01e-40 | FFCP PHASE1:Hg19::chr1:24645071..24645074,+#_13badbbfec036da9148c7d20b56ef664 | p@chr1:24645071..24645074, + |
| 3.01e-40 | FFCP PHASE2:Hg19::chr1:24645071..24645074,+#_13badbbfec036da9148c7d20b56ef664 | p@chr1:24645071..24645074, + |
| 5.49e-40 | FFCP PHASE2:Hg19::chr2:179739649..179739660,-#_a8ead261893d870e58eeb6dccde62927 | p@chr2:179739649..179739660, - |
| 5.49e-40 | FFCP PHASE2:Hg19::chr6:33161034..33161047,-#_a8ead261893d870e58eeb6dccde62927 | p@chr6:33161034..33161047, - |
| 5.49e-40 | FFCP PHASE1:Hg19::chr6:33161034..33161047,-#_a8ead261893d870e58eeb6dccde62927 | p@chr6:33161034..33161047, - |
| 5.49e-40 | FFCP PHASE1:Hg19::chr2:179739649..179739660,-#_a8ead261893d870e58eeb6dccde62927 | p@chr2:179739649..179739660, - |
| 6.7e-40 | FFCP PHASE1:Hg19::chr6:151670422..151670433,+#_3985747ae8d07c3ee1ddba19fbe928ca | p@chr6:151670422..151670433, + |
| 6.7e-40 | FFCP PHASE2:Hg19::chr6:151670422..151670433,+#_3985747ae8d07c3ee1ddba19fbe928ca | p@chr6:151670422..151670433, + |
| 2.27e-37 | FFCP PHASE1:Hg19::chr11:121976070..121976081,-#_6ec942f19eeff98e77bfe71db2d2c05d | p4@ENST00000534195 |
| 2.27e-37 | FFCP PHASE2:Hg19::chr11:121976070..121976081,-#_6ec942f19eeff98e77bfe71db2d2c05d | p4@ENST00000534195 |
| 2.73e-37 | FFCP PHASE1:Hg19::chr2:25720514..25720525,-#_318a3ce7e6705d493a6e3a992a4d87d2 | p16@DTNB |
| 2.73e-37 | FFCP PHASE2:Hg19::chr2:25720514..25720525,-#_318a3ce7e6705d493a6e3a992a4d87d2 | p16@DTNB |
| 3.28e-37 | FFCP PHASE1:Hg19::chr17:11144580..11144595,+#_52931458b0cf44b41d92583125fc8af4 | p2@SHISA6 |
| 3.28e-37 | FFCP PHASE2:Hg19::chr17:42984370..42984375,-#_52931458b0cf44b41d92583125fc8af4 | p42@GFAP |
| 3.28e-37 | FFCP PHASE2:Hg19::chr17:11144580..11144595,+#_52931458b0cf44b41d92583125fc8af4 | p2@SHISA6 |
| 3.28e-37 | FFCP PHASE1:Hg19::chr17:42984370..42984375,-#_52931458b0cf44b41d92583125fc8af4 | p42@GFAP |
