CL:0000182: Difference between revisions
From FANTOM5_SSTAR
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|id=CL:0000182
|name=hepatocyte
|namespace=cell
|def="The main structural component of the liver. They are specialized epithelial cells that are organized into interc...") |
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|id=CL:0000182 | |id=CL:0000182 | ||
|name=hepatocyte | |name=hepatocyte | ||
|namespace= | |namespace=efo | ||
|def="The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, ISBN:0412046911, MESH:A.11.436.348, PMID:19717280] | |def="The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, ISBN:0412046911, MESH:A.11.436.348, PMID:19717280] | ||
|xref=BTO:0000575;;FMA:14515 | |xref=BTO:0000575;;FMA:14515 | ||
|is_a=CL:0000066;;CL:0000181;;CL:0000417;;CL:0002371 | |is_a=CL:0000066;;CL:0000181;;CL:0000417;;CL:0000668;;CL:0002371;;EFO:0000324 | ||
|synonym= | |synonym= | ||
|comment= | |comment= | ||
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|located_in= | |located_in= | ||
|part_of=UBERON:0002107 | |part_of=UBERON:0002107 | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.obo.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl | |||
|is_obsolete= | |||
|preceded_by= | |||
}} | }} | ||
Revision as of 17:36, 15 June 2012
| Name: | hepatocyte | ||
|---|---|---|---|
| Namespace: | efo | ||
| Definition: | "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, ISBN:0412046911, MESH:A.11.436.348, PMID:19717280] | ||
| Xrefs: |
|
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000066(epithelial cell),CL:0000181(metabolising cell),CL:0000417(endopolyploid cell),CL:0000668(parenchymal cell),CL:0002371(somatic cell),EFO:0000324(cell type) |
|---|---|
| develops_from: | CL:0000134(mesenchymal cell),CL:0000223(endodermal cell) |
| part_of: | UBERON:0002107(liver) |
Children
| is a: | FF:0000018 (canine hepatocyte),FF:0000034 (chicken hepatocyte),FF:0000150 (rat hepatocyte),CL:0002538 (intrahepatic bile duct epithelial cell),CL:1000398 (endothelial cell of hepatic sinusoid),FF:13580-146C7 (hepatocytes, sham operation, biol_rep1),FF:13581-146C8 (hepatocytes, sham operation, biol_rep2),FF:13582-146C9 (hepatocytes, sham operation, biol_rep3),FF:13583-146D1 (hepatocytes, partial hepatectomy, 02hr, biol_rep1),FF:13584-146D2 (hepatocytes, partial hepatectomy, 02hr, biol_rep2),FF:13585-146D3 (hepatocytes, partial hepatectomy, 02hr, biol_rep3),FF:13586-146D4 (hepatocytes, partial hepatectomy, 30hr, biol_rep1) |
|---|---|
| derives from: | FF:0000078 (human hepatocyte sample),FF:0000109 (mouse hepatocyte sample),FF:0100578 (hepatoma cell line sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10484-107A7 (hepatoma cell line:Li-7)
- 10536-107G5 (cholangiocellular carcinoma cell line:HuH-28)
- 10629-108H8
- 10630-108H9
- 10632-108I2
- 10633-108I3 (hepatoblastoma cell line:HuH-6)
- 10706-109H4 (pleomorphic hepatocellular carcinoma cell line:SNU-387)
- 10746-110C8
- 10818-111B8 (hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1)
- 10819-111B9 (hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2)
... further results Mouse (Mus musculus)
- 10484-107A7 (hepatoma cell line:Li-7)
- 10536-107G5 (cholangiocellular carcinoma cell line:HuH-28)
- 10629-108H8
- 10630-108H9
- 10632-108I2
- 10633-108I3 (hepatoblastoma cell line:HuH-6)
- 10706-109H4 (pleomorphic hepatocellular carcinoma cell line:SNU-387)
- 10746-110C8
- 10818-111B8 (hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1)
- 10819-111B9 (hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000182 (hepatocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 4.17e-100 | FFCP PHASE2:Hg19::chr8:144417558..144417572,-#_2974b40250489bc45f20db3ecf938793 | p7@TOP1MT |
| 4.17e-100 | FFCP PHASE1:Hg19::chr8:144417558..144417572,-#_2974b40250489bc45f20db3ecf938793 | p7@TOP1MT |
| 3.95e-89 | FFCP PHASE2:Hg19::chr20:22566089..22566097,-#_f0f0ee65556efa66005c2e1af9460cb1 | p6@FOXA2 |
| 3.95e-89 | FFCP PHASE1:Hg19::chr20:22566089..22566097,-#_f0f0ee65556efa66005c2e1af9460cb1 | p6@FOXA2 |
| 2.29e-84 | FFCP PHASE2:Hg19::chr2:44066386..44066398,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p6@ABCG5 |
| 2.29e-84 | FFCP PHASE1:Hg19::chr2:21232865..21232870,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p10@BC172787 |
| 2.29e-84 | FFCP PHASE2:Hg19::chr2:21234502..21234510,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p43@APOB |
| 2.29e-84 | FFCP PHASE1:Hg19::chr2:44066386..44066398,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p6@ABCG5 |
| 2.29e-84 | FFCP PHASE1:Hg19::chr2:21234502..21234510,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p43@APOB |
| 2.29e-84 | FFCP PHASE2:Hg19::chr2:21232865..21232870,-#_9e2e6823a3c994cfd331c4f6643a42a2 | p10@BC172787 |
| 2.65e-84 | FFCP PHASE1:Hg19::chr10:7763609..7763619,+#_5dcc33756ba050484247ffd195c229e4 | p@chr10:7763609..7763619, + |
| 2.65e-84 | FFCP PHASE2:Hg19::chr10:7763609..7763619,+#_5dcc33756ba050484247ffd195c229e4 | p@chr10:7763609..7763619, + |
| 3.05e-84 | FFCP PHASE1:Hg19::chr2:21230675..21230682,-#_426e280c142806c86d76fef893d3e9c5 | p51@APOB |
| 3.05e-84 | FFCP PHASE2:Hg19::chr2:21230675..21230682,-#_426e280c142806c86d76fef893d3e9c5 | p51@APOB |
| 4.43e-82 | FFCP PHASE2:Hg19::chr20:62655876..62655885,+#_8d3669c8dfefc139128946a391aacd62 | p@chr20:62655876..62655885, + |
| 4.43e-82 | FFCP PHASE1:Hg19::chr20:62655876..62655885,+#_8d3669c8dfefc139128946a391aacd62 | p@chr20:62655876..62655885, + |
| 5.2e-74 | FFCP PHASE1:Hg19::chr2:21236080..21236092,-#_ea5aafee6b63bed74dc1d4bd96c2f5cf | p3@BC172786 |
| 5.2e-74 | FFCP PHASE2:Hg19::chr2:21233797..21233804,-#_ea5aafee6b63bed74dc1d4bd96c2f5cf | p58@APOB |
| 5.2e-74 | FFCP PHASE1:Hg19::chr2:21233797..21233804,-#_ea5aafee6b63bed74dc1d4bd96c2f5cf | p58@APOB |
| 5.2e-74 | FFCP PHASE2:Hg19::chr2:21236080..21236092,-#_ea5aafee6b63bed74dc1d4bd96c2f5cf | p3@BC172786 |
| 5.9e-74 | FFCP PHASE1:Hg19::chr2:21233959..21233966,-#_ba2961f01356059e8d45f3dced61d3eb | p50@APOB |
| 5.9e-74 | FFCP PHASE1:Hg19::chr2:21242732..21242744,-#_ba2961f01356059e8d45f3dced61d3eb | p@chr2:21242732..21242744, - |
| 5.9e-74 | FFCP PHASE2:Hg19::chr2:21229230..21229239,-#_ba2961f01356059e8d45f3dced61d3eb | p@chr2:21229230..21229239, - |
| 5.9e-74 | FFCP PHASE2:Hg19::chr2:21233959..21233966,-#_ba2961f01356059e8d45f3dced61d3eb | p50@APOB |
| 5.9e-74 | FFCP PHASE1:Hg19::chr2:21229230..21229239,-#_ba2961f01356059e8d45f3dced61d3eb | p@chr2:21229230..21229239, - |
| 5.9e-74 | FFCP PHASE2:Hg19::chr2:21242732..21242744,-#_ba2961f01356059e8d45f3dced61d3eb | p@chr2:21242732..21242744, - |
| 6.69e-74 | FFCP PHASE1:Hg19::chr2:21225230..21225237,-#_4c1c37f1e85f3f51f800e426bdcf6f3d | p60@APOB |
| 6.69e-74 | FFCP PHASE2:Hg19::chr2:21225230..21225237,-#_4c1c37f1e85f3f51f800e426bdcf6f3d | p60@APOB |
| 7.59e-74 | FFCP PHASE2:Hg19::chr2:21228952..21228959,-#_c7031b2c84e4995e7f11917c30543096 | p66@APOB |
| 7.59e-74 | FFCP PHASE1:Hg19::chr2:21228952..21228959,-#_c7031b2c84e4995e7f11917c30543096 | p66@APOB |
| 8.6e-74 | FFCP PHASE2:Hg19::chr2:21234262..21234269,-#_35d2506dc042ade728b8c8e2b7e0e8fa | p70@APOB |
| 8.6e-74 | FFCP PHASE2:Hg19::chr14:94759387..94759403,-#_35d2506dc042ade728b8c8e2b7e0e8fa | p4@SERPINA10 |
| 8.6e-74 | FFCP PHASE1:Hg19::chr14:94759387..94759403,-#_35d2506dc042ade728b8c8e2b7e0e8fa | p4@SERPINA10 |
| 8.6e-74 | FFCP PHASE1:Hg19::chr2:21234262..21234269,-#_35d2506dc042ade728b8c8e2b7e0e8fa | p70@APOB |
| 2.07e-73 | FFCP PHASE2:Hg19::chr2:21257701..21257711,+#_71724f7700544024cb7104e7f5f92ef4 | p@chr2:21257701..21257711, + |
| 2.07e-73 | FFCP PHASE1:Hg19::chr2:21257701..21257711,+#_71724f7700544024cb7104e7f5f92ef4 | p@chr2:21257701..21257711, + |
| 6.33e-73 | FFCP PHASE1:Hg19::chrX:153769426..153769436,+#_45fb0bb6d20688a35c439fbefc854b27 | p18@IKBKG |
| 6.33e-73 | FFCP PHASE2:Hg19::chrX:153769426..153769436,+#_45fb0bb6d20688a35c439fbefc854b27 | p18@IKBKG |
| 6.33e-73 | FFCP PHASE1:Hg19::chr10:7745167..7745178,+#_45fb0bb6d20688a35c439fbefc854b27 | p3@ITIH2 |
| 6.33e-73 | FFCP PHASE2:Hg19::chr10:7745167..7745178,+#_45fb0bb6d20688a35c439fbefc854b27 | p3@ITIH2 |
| 1.49e-72 | FFCP PHASE1:Hg19::chr2:97216132..97216143,+#_6133edde72e1af8547069d18351f7743 | p@chr2:97216132..97216143, + |
| 1.49e-72 | FFCP PHASE2:Hg19::chr2:97216132..97216143,+#_6133edde72e1af8547069d18351f7743 | p@chr2:97216132..97216143, + |
| 5.78e-72 | FFCP PHASE2:Mm9::chr4:60016350..60016358,+#_d134f5d5b25084c520ade697a4332005 | p1@Mup6 |
| 5.78e-72 | FFCP PHASE1:Mm9::chr4:60016350..60016358,+#_d134f5d5b25084c520ade697a4332005 | p1@Mup6 |
| 1.06e-69 | FFCP PHASE2:Hg19::chr12:24191262..24191291,-#_a4d64177f8f7cafd24bdce6efb31d6c4 | p@chr12:24191262..24191291, - |
| 1.06e-69 | FFCP PHASE1:Hg19::chr12:24191262..24191291,-#_a4d64177f8f7cafd24bdce6efb31d6c4 | p@chr12:24191262..24191291, - |
| 1.65e-69 | FFCP PHASE2:Mm9::chr15:54650539..54650542,-#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr15:54650539..54650542, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr15:54650539..54650542,-#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr15:54650539..54650542, - |
| 1.65e-69 | FFCP PHASE2:Mm9::chr2:104426232..104426235,+#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr2:104426232..104426235, + |
| 1.65e-69 | FFCP PHASE2:Mm9::chr9:46038167..46038172,-#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr9:46038167..46038172, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr9:46038167..46038172,-#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr9:46038167..46038172, - |
| 1.65e-69 | FFCP PHASE1:Mm9::chr2:104426232..104426235,+#_047b5ae1011dc3571ab68d5e15a0c1a5 | p@chr2:104426232..104426235, + |
| 1.26e-68 | FFCP PHASE2:Hg19::chr2:21228923..21228930,-#_8d5025425504cdf8ebe515509653bd79 | p94@APOB |
| 1.26e-68 | FFCP PHASE2:Hg19::chr9:107651917..107651931,-#_8d5025425504cdf8ebe515509653bd79 | p11@ABCA1 |
| 1.26e-68 | FFCP PHASE2:Hg19::chr20:62655807..62655838,+#_8d5025425504cdf8ebe515509653bd79 | p@chr20:62655807..62655838, + |
| 1.26e-68 | FFCP PHASE1:Hg19::chr2:21228923..21228930,-#_8d5025425504cdf8ebe515509653bd79 | p94@APOB |
| 1.26e-68 | FFCP PHASE1:Hg19::chr9:107651917..107651931,-#_8d5025425504cdf8ebe515509653bd79 | p11@ABCA1 |
| 1.26e-68 | FFCP PHASE1:Hg19::chr10:7755243..7755254,-#_8d5025425504cdf8ebe515509653bd79 | p@chr10:7755243..7755254, - |
| 1.26e-68 | FFCP PHASE1:Hg19::chr20:62655807..62655838,+#_8d5025425504cdf8ebe515509653bd79 | p@chr20:62655807..62655838, + |
| 1.26e-68 | FFCP PHASE2:Hg19::chr10:7755243..7755254,-#_8d5025425504cdf8ebe515509653bd79 | p@chr10:7755243..7755254, - |
| 1.45e-68 | FFCP PHASE2:Hg19::chr2:21229212..21229220,-#_9c043e1af5ab272f136ee1f8387baeff | p@chr2:21229212..21229220, - |
| 1.45e-68 | FFCP PHASE2:Hg19::chr2:21232174..21232177,-#_9c043e1af5ab272f136ee1f8387baeff | p13@BC172787 |
| 1.45e-68 | FFCP PHASE1:Hg19::chr2:21229212..21229220,-#_9c043e1af5ab272f136ee1f8387baeff | p@chr2:21229212..21229220, - |
| 1.45e-68 | FFCP PHASE1:Hg19::chr2:21232174..21232177,-#_9c043e1af5ab272f136ee1f8387baeff | p13@BC172787 |
| 1.67e-68 | FFCP PHASE1:Hg19::chr2:219613831..219613849,+#_6ed393ba617f39f1c52cacde2dd43037 | p@chr2:219613831..219613849, + |
| 1.67e-68 | FFCP PHASE2:Hg19::chr2:219613831..219613849,+#_6ed393ba617f39f1c52cacde2dd43037 | p@chr2:219613831..219613849, + |
| 1.67e-68 | FFCP PHASE2:Hg19::chr2:21234575..21234582,-#_6ed393ba617f39f1c52cacde2dd43037 | p78@APOB |
| 1.67e-68 | FFCP PHASE1:Hg19::chr2:21234575..21234582,-#_6ed393ba617f39f1c52cacde2dd43037 | p78@APOB |
| 2.21e-68 | FFCP PHASE2:Hg19::chr14:94759408..94759416,-#_62ec3fe3f7faf56c0c3cef456664957b | p6@SERPINA10 |
| 2.21e-68 | FFCP PHASE1:Hg19::chr14:94759408..94759416,-#_62ec3fe3f7faf56c0c3cef456664957b | p6@SERPINA10 |
| 2.21e-68 | FFCP PHASE2:Hg19::chr2:21231259..21231266,-#_62ec3fe3f7faf56c0c3cef456664957b | p84@APOB |
| 2.21e-68 | FFCP PHASE1:Hg19::chr2:21231259..21231266,-#_62ec3fe3f7faf56c0c3cef456664957b | p84@APOB |
| 2.54e-68 | FFCP PHASE1:Hg19::chr18:32508476..32508518,-#_e59668b3806123412b5917247bd77fad | p@chr18:32508476..32508518, - |
| 2.54e-68 | FFCP PHASE2:Hg19::chr18:32508476..32508518,-#_e59668b3806123412b5917247bd77fad | p@chr18:32508476..32508518, - |
| 2.71e-67 | FFCP PHASE2:Hg19::chr17:7082560..7082572,-#_49838dcf808d1f905c43e3f94b2cc7bb | p4@ASGR1 |
| 2.71e-67 | FFCP PHASE1:Hg19::chr17:7082560..7082572,-#_49838dcf808d1f905c43e3f94b2cc7bb | p4@ASGR1 |
| 3.3e-67 | FFCP PHASE2:Hg19::chr10:72083665..72083701,-#_052fab90428e93d3c888629720328455 | p2@LRRC20 |
| 3.3e-67 | FFCP PHASE1:Hg19::chr10:72083665..72083701,-#_052fab90428e93d3c888629720328455 | p2@LRRC20 |
| 5.39e-67 | FFCP PHASE2:Hg19::chr2:21233386..21233397,-#_206d5723072dd22e52b5c38a0789ecae | p22@APOB |
| 5.39e-67 | FFCP PHASE1:Hg19::chr2:21233386..21233397,-#_206d5723072dd22e52b5c38a0789ecae | p22@APOB |
| 5.94e-67 | FFCP PHASE1:Hg19::chr12:24191210..24191221,-#_ee3a6cbbb7d47a692e766e81b263d4cb | p@chr12:24191210..24191221, - |
| 5.94e-67 | FFCP PHASE2:Hg19::chr12:24191210..24191221,-#_ee3a6cbbb7d47a692e766e81b263d4cb | p@chr12:24191210..24191221, - |
| 6.56e-67 | FFCP PHASE1:Hg19::chr6:30130969..30131007,+#_d9e28319635314d50e83be12c2b8499b | p3@TRIM15 |
| 6.56e-67 | FFCP PHASE2:Hg19::chr6:30130969..30131007,+#_d9e28319635314d50e83be12c2b8499b | p3@TRIM15 |
| 7.97e-67 | FFCP PHASE2:Hg19::chr9:116838918..116838930,-#_d789e448e3f08dc8eb72cfedc6c87260 | p@chr9:116838918..116838930, - |
| 7.97e-67 | FFCP PHASE1:Hg19::chr9:116838918..116838930,-#_d789e448e3f08dc8eb72cfedc6c87260 | p@chr9:116838918..116838930, - |
| 1.07e-66 | FFCP PHASE2:Hg19::chr3:197300199..197300219,-#_16857e3dafc8878eeea246dacfd5c9bf | p2@BDH1 |
| 1.07e-66 | FFCP PHASE1:Hg19::chr3:197300199..197300219,-#_16857e3dafc8878eeea246dacfd5c9bf | p2@BDH1 |
| 1.18e-66 | FFCP PHASE2:Hg19::chr1:11107289..11107304,-#_45884abe20a3825517415604f2f0ec9f | p1@MASP2 |
| 1.18e-66 | FFCP PHASE1:Hg19::chr1:11107289..11107304,-#_45884abe20a3825517415604f2f0ec9f | p1@MASP2 |
| 1.3e-66 | FFCP PHASE2:Hg19::chr19:45430057..45430062,+#_fe09b2506314102d42197764537baa3d | p1@APOC1P1 |
| 1.3e-66 | FFCP PHASE1:Hg19::chr19:45430057..45430062,+#_fe09b2506314102d42197764537baa3d | p1@APOC1P1 |
| 1.58e-66 | FFCP PHASE1:Hg19::chr4:155528001..155528060,-#_ab69eafe34b5cae4f1e0a31f259f0a56 | p@chr4:155528001..155528060, - |
| 1.58e-66 | FFCP PHASE1:Hg19::chr9:116838988..116838999,-#_ab69eafe34b5cae4f1e0a31f259f0a56 | p@chr9:116838988..116838999, - |
| 1.58e-66 | FFCP PHASE2:Hg19::chr4:155528001..155528060,-#_ab69eafe34b5cae4f1e0a31f259f0a56 | p@chr4:155528001..155528060, - |
| 1.58e-66 | FFCP PHASE2:Hg19::chr9:116838988..116838999,-#_ab69eafe34b5cae4f1e0a31f259f0a56 | p@chr9:116838988..116838999, - |
| 2.12e-66 | FFCP PHASE1:Hg19::chr11:116662593..116662620,-#_781b9565b0c947becd10d556f3ddda22 | p1@APOA5 |
| 2.12e-66 | FFCP PHASE2:Hg19::chr11:116662593..116662620,-#_781b9565b0c947becd10d556f3ddda22 | p1@APOA5 |
| 2.34e-66 | FFCP PHASE1:Hg19::chr17:7017634..7017649,-#_eb2cf291ad114667cb90c45ac9230918 | p7@ASGR2 |
| 2.34e-66 | FFCP PHASE2:Hg19::chr17:7017634..7017649,-#_eb2cf291ad114667cb90c45ac9230918 | p7@ASGR2 |
