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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C441_keratoacanthoma_skin_tongue_esophagus_cervical_salivary_Sebocyte
|full_id=C441_keratoacanthoma_skin_tongue_esophagus_cervical_salivary_Sebocyte
|gostat_on_coexpression_clusters=GO:0035247!peptidyl-arginine omega-N-methylation!0.00691705418196945!56341$GO:0019919!peptidyl-arginine methylation, to asymmetrical-dimethyl arginine!0.00691705418196945!56341$GO:0035246!peptidyl-arginine N-methylation!0.00691705418196945!56341$GO:0035241!protein-arginine omega-N monomethyltransferase activity!0.00691705418196945!56341$GO:0018216!peptidyl-arginine methylation!0.00829997633890119!56341$GO:0008469!histone-arginine N-methyltransferase activity!0.0103731380914246!56341$GO:0016274!protein-arginine N-methyltransferase activity!0.0103731380914246!56341$GO:0016273!arginine N-methyltransferase activity!0.0103731380914246!56341$GO:0018195!peptidyl-arginine modification!0.0124455672994332!56341$GO:0016571!histone methylation!0.0124455672994332!56341$GO:0008889!glycerophosphodiester phosphodiesterase activity!0.0149772478673127!54857$GO:0043393!regulation of protein binding!0.0149772478673127!56341$GO:0008213!protein amino acid alkylation!0.0207279625682647!56341$GO:0006479!protein amino acid methylation!0.0207279625682647!56341$GO:0051098!regulation of binding!0.0257841692883749!56341$GO:0042054!histone methyltransferase activity!0.0275901361221504!56341$GO:0031424!keratinization!0.0275901361221504!353144$GO:0006071!glycerol metabolic process!0.0275901361221504!54857$GO:0019751!polyol metabolic process!0.0275901361221504!54857$GO:0043414!biopolymer methylation!0.0275901361221504!56341$GO:0016570!histone modification!0.0275901361221504!56341$GO:0008276!protein methyltransferase activity!0.0275901361221504!56341$GO:0009913!epidermal cell differentiation!0.0275901361221504!353144$GO:0008170!N-methyltransferase activity!0.0275901361221504!56341$GO:0016569!covalent chromatin modification!0.0275901361221504!56341$GO:0048730!epidermis morphogenesis!0.0291732855349702!353144$GO:0032259!methylation!0.0354271151573729!56341$GO:0048729!tissue morphogenesis!0.0354271151573729!353144$GO:0005886!plasma membrane!0.038525270902211!84290;54857;56341$GO:0008757!S-adenosylmethionine-dependent methyltransferase activity!0.0394621325759638!56341$GO:0046982!protein heterodimerization activity!0.0465741722799623!56341
|id=C441
|id=C441
}}
}}

Revision as of 17:40, 18 May 2012


Full id: C441_keratoacanthoma_skin_tongue_esophagus_cervical_salivary_Sebocyte



Phase1 CAGE Peaks

Hg19::chr10:8636368..8636400,-p@chr10:8636368..8636400
-
Hg19::chr12:3600112..3600125,+p6@PRMT8
Hg19::chr14:23777595..23777607,-p@chr14:23777595..23777607
-
Hg19::chr14:23777630..23777642,-p@chr14:23777630..23777642
-
Hg19::chr14:23777647..23777667,-p@chr14:23777647..23777667
-
Hg19::chr16:55600580..55600632,+p1@CAPNS2
Hg19::chr16:55600644..55600645,+p2@CAPNS2
Hg19::chr16:80586313..80586337,-p@chr16:80586313..80586337
-
Hg19::chr17:39672442..39672463,+p@chr17:39672442..39672463
+
Hg19::chr17:39674844..39674854,+p@chr17:39674844..39674854
+
Hg19::chr17:40324009..40324020,-p@chr17:40324009..40324020
-
Hg19::chr1:151826134..151826143,-p2@THEM5
Hg19::chr1:151826151..151826159,-p3@THEM5
Hg19::chr1:151826179..151826192,-p1@THEM5
Hg19::chr1:152572708..152572714,+p1@LCE3C
Hg19::chr1:236247199..236247215,-p@chr1:236247199..236247215
-
Hg19::chr20:10727793..10727802,+p@chr20:10727793..10727802
+
Hg19::chr9:97563025..97563035,+p@chr9:97563025..97563035
+
Hg19::chr9:97563078..97563086,+p@chr9:97563078..97563086
+
Hg19::chr9:97563106..97563117,+p@chr9:97563106..97563117
+
Hg19::chrX:69643154..69643183,+p1@GDPD2
Hg19::chrX:69643186..69643195,+p4@GDPD2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0035247peptidyl-arginine omega-N-methylation0.00691705418196945
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine0.00691705418196945
GO:0035246peptidyl-arginine N-methylation0.00691705418196945
GO:0035241protein-arginine omega-N monomethyltransferase activity0.00691705418196945
GO:0018216peptidyl-arginine methylation0.00829997633890119
GO:0008469histone-arginine N-methyltransferase activity0.0103731380914246
GO:0016274protein-arginine N-methyltransferase activity0.0103731380914246
GO:0016273arginine N-methyltransferase activity0.0103731380914246
GO:0018195peptidyl-arginine modification0.0124455672994332
GO:0016571histone methylation0.0124455672994332
GO:0008889glycerophosphodiester phosphodiesterase activity0.0149772478673127
GO:0043393regulation of protein binding0.0149772478673127
GO:0008213protein amino acid alkylation0.0207279625682647
GO:0006479protein amino acid methylation0.0207279625682647
GO:0051098regulation of binding0.0257841692883749
GO:0042054histone methyltransferase activity0.0275901361221504
GO:0031424keratinization0.0275901361221504
GO:0006071glycerol metabolic process0.0275901361221504
GO:0019751polyol metabolic process0.0275901361221504
GO:0043414biopolymer methylation0.0275901361221504
GO:0016570histone modification0.0275901361221504
GO:0008276protein methyltransferase activity0.0275901361221504
GO:0009913epidermal cell differentiation0.0275901361221504
GO:0008170N-methyltransferase activity0.0275901361221504
GO:0016569covalent chromatin modification0.0275901361221504
GO:0048730epidermis morphogenesis0.0291732855349702
GO:0032259methylation0.0354271151573729
GO:0048729tissue morphogenesis0.0354271151573729
GO:0005886plasma membrane0.038525270902211
GO:0008757S-adenosylmethionine-dependent methyltransferase activity0.0394621325759638
GO:0046982protein heterodimerization activity0.0465741722799623



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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