MCL coexpression mm9:37: Difference between revisions
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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0006810;transport;2.35252618387158e-06;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0051234;establishment of localization;2.72945389052599e-06;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0051179;localization;6.25990538970619e-05;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0005988;lactose metabolic process;0.00103749092956346;14595,16770!GO:0046351;disaccharide biosynthetic process;0.00103749092956346;14595,16770!GO:0005989;lactose biosynthetic process;0.00103749092956346;14595,16770!GO:0007595;lactation;0.00108201299969242;20850,11941,102247!GO:0022857;transmembrane transporter activity;0.00165959695027517;57776,11941,67547,110895,117591,20531,114304,13358,69047,18671,52150!GO:0045136;development of secondary sexual characteristics;0.0016946117554734;20850,14595!GO:0005984;disaccharide metabolic process;0.0016946117554734;14595,16770!GO:0004461;lactose synthase activity;0.0016946117554734;14595,16770!GO:0022804;active transmembrane transporter activity;0.00191021098707246;11941,110895,117591,20531,114304,69047,18671!GO:0030879;mammary gland development;0.00194436123413886;20850,102247,14595!GO:0048609;reproductive process in a multicellular organism;0.00257607964279661;20850,11941,102247,14595!GO:0032504;multicellular organism reproduction;0.00257607964279661;20850,11941,102247,14595!GO:0005615;extracellular space;0.00339931704540711;14663,12990,100470,12993,67547,76113,14275,269328,22373,16770,109685,12992,20443,56745,22041!GO:0030855;epithelial cell differentiation;0.0067022668040256;20850,102247,14595!GO:0002064;epithelial cell development;0.00719638305535339;102247,14595!GO:0044421;extracellular region part;0.00784392583037299;14663,12990,100470,12993,67547,76113,14275,269328,22373,16770,109685,12992,20443,56745,22041!GO:0008180;signalosome;0.0108614200215987;12848,26572!GO:0022414;reproductive process;0.0108614200215987;50500,20850,11941,102247,14595!GO:0006812;cation transport;0.0108614200215987;11941,67547,110895,20531,69047,52150,22041!GO:0006811;ion transport;0.0239605402974435;57776,11941,67547,110895,20531,69047,52150,22041!GO:0030001;metal ion transport;0.0261333147095886;11941,67547,110895,20531,52150,22041!GO:0022891;substrate-specific transmembrane transporter activity;0.0270278510339958;57776,11941,67547,117591,20531,114304,69047,52150!GO:0022892;substrate-specific transporter activity;0.0283756944341974;57776,11941,67547,117591,20531,114304,69047,52150,68159!GO:0035250;UDP-galactosyltransferase activity;0.034232902800599;14595,16770!GO:0048732;gland development;0.034232902800599;20850,102247,14595!GO:0015291;secondary active transmembrane transporter activity;0.0405054212757056;110895,117591,20531,114304!GO:0015075;ion transmembrane transporter activity;0.0405054212757056;57776,11941,67547,20531,114304,69047,52150!GO:0003836;beta-galactoside alpha-2,3-sialyltransferase activity;0.0405054212757056;20443!GO:0031527;filopodium membrane;0.0405054212757056;57776!GO:0032433;filopodium tip;0.0405054212757056;57776!GO:0006494;protein amino acid terminal glycosylation;0.0405054212757056;14595!GO:0005345;purine transmembrane transporter activity;0.0405054212757056;114304!GO:0045299;otolith mineralization;0.0405054212757056;11941!GO:0006496;protein amino acid terminal N-glycosylation;0.0405054212757056;14595!GO:0042360;vitamin E metabolic process;0.0405054212757056;50500!GO:0060055;angiogenesis involved in wound healing;0.0405054212757056;14595!GO:0002067;glandular epithelial cell differentiation;0.0405054212757056;102247!GO:0060057;apoptosis involved in mammary gland involution;0.0405054212757056;14595!GO:0042392;sphingosine-1-phosphate phosphatase activity;0.0405054212757056;81535!GO:0060058;positive regulation of apoptosis involved in mammary gland involution;0.0405054212757056;14595!GO:0008431;vitamin E binding;0.0405054212757056;50500!GO:0060054;positive regulation of epithelial cell proliferation involved in wound healing;0.0405054212757056;14595!GO:0015864;pyrimidine nucleoside transport;0.0405054212757056;114304!GO:0046655;folic acid metabolic process;0.0405054212757056;14275!GO:0015389;pyrimidine- and adenine-specific:sodium symporter activity;0.0405054212757056;114304!GO:0015390;purine-specific nucleoside:sodium symporter activity;0.0405054212757056;114304!GO:0060046;regulation of acrosome reaction;0.0405054212757056;14595!GO:0008780;acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity;0.0405054212757056;102247!GO:0002068;glandular epithelial cell development;0.0405054212757056;102247!GO:0008778;acyl-CoA thioesterase II activity;0.0405054212757056;99035!GO:0002071;glandular epithelial cell maturation;0.0405054212757056;102247!GO:0002069;columnar/cuboidal epithelial cell maturation;0.0405054212757056;102247!GO:0008378;galactosyltransferase activity;0.042962597152541;14595,16770!GO:0032787;monocarboxylic acid metabolic process;0.0432121808003774;102247,14275,99035,107476!GO:0019842;vitamin binding;0.0449189028486131;50500,14275,107476!}} | {{MCL_coexpression_mm9 | ||
|coexpression_dpi_cluster_scores_mean=0.0145760586014217,0.0104397681204674,0.0169535166268505,0.000991968735435135,0.00176095669831798,0.0129537729333905,0.0138024094212654,-0.00270285600682897,0.00383271907864376,0.00848412165475121,-0.0089736406589947,-0.00893585903799644,-0.00687452000314968,-0.00797204633657322,-0.00438462854272597,-0.0019590757291101,-0.00379393870660278,-0.00375728608225479,-0.00377649184443796,-0.00571498825911585,0.0306278044977398,0.00288526113558931,0.000387263078296788,0.0161261466320572,0.0202977567502713,0.0137149854132913,0.0172528305279108,0.018251815972161,0.0101297242072631,0.00729838265436582,0.0190437693619872,-0.00511907535538103,-0.00403604885809726,-0.020647461685112,-0.00238918069449373,-0.000814827367449527,-0.000497325851520682,0.00171006176978861,-0.000944646242033515,0.00167986239895024,0.00358526311926412,0.00524715863279417,0.00278289389294342,0.0110509874955013,0.0107978402874166,0.00779483731564862,0.012350895300226,-0.001894264567957,0.00360600033714953,0.00617179791844151,0.00946407775154592,0.00106843181745963,-0.00482289652436519,-0.00780483251276915,-0.00295420588593453,0.024691229862231,0.0171729229021267,0.0216363330259648,1.03850763717484e-07,0.00428581407226822,-0.00208148638274059,0.00642177557603912,0.0105871847385288,0.00750170869081265,0.0167818143665915,0.00739318435218434,0.0182838297533167,0.0185000082438566,-0.0109670337163202,-0.0105226209822578,-0.0115499180617288,-0.00165171535068251,0.00272460281877135,-0.0103258011656078,-0.00923890510434104,-0.0124640048987651,0.00418284320044156,0.0025819385098149,0.00185858380898839,-0.00401579490628902,-0.00283802294702811,-0.00631266030347331,0.00471036992537275,0.00159535375569138,0.003454217590015,0.00305851534001048,0.00311429182098342,-0.00433391456749038,0.00104157654971069,0.0106021884507159,0.0403937871399085,0.0194390060027421,0.0129057822455413,0.0110219882357702,0.0172504394676141,0.0171325342568205,0.0541695336071155,0.0173113925963521,0.0183769060129269,0.0162888142950378,0.0177383739930108,0.00417161323938387,0.00830041085969592,-0.00029450805361731,0.0303140332724973,0.0267876064277919,0.0241495413155157,0.045314957019812,0.0171611904915032,0.0118724244158915,0.00377534411650734,0.00674142742970945,0.0049619602611004,0.00664665720175801,0.0102138040888126,0.0162573630297917,0.0387620569876393,0.0258426526953084,0.00694596238031869,0.0125873340480326,0.0145951942420081,0.018936432666762,0.0099252141731844,0.00185786746268544,0.00600447630514855,0.0173807505690985,-0.000922001277767688,-0.003699462692539,0.00012678475134914,0.00611427027519074,0.00516969203127498,-0.00611421617305468,-0.00324088585014185,-0.00345613219600471,0.00597417529736221,0.00270797979451368,0.01017540053527,0.0338150897474966,0.0497267438494158,0.0621630832736816,0.00610716272199584,0.00489349573695919,0.00756465888909152,0.015694874212576,0.0123548325248373,0.0128457066430667,0.0154154819809029,0.045008919012685,-0.00447277559547177,0.00198327888442011,0.00673869258102811,0.0110141822961415,0.0172403451737145,0.0243783182624912,0.0240657084666238,0.00619288426626948,-0.00262306002259925,-0.00194171640110353,0.00062586001977691,-0.000172369991620473,0.00587780471267501,0.00346437539206488,0.01406224389907,0.00867668897699076,0.00864995246593662,0.0089312662008938,0.0114841041097353,0.00777122615507566,0.00742701688750154,0.00607142095768633,0.00956764132194316,0.00630167003031053,0.0105857131449487,0.0081679265062607,-0.00054085382732782,-0.00254786922371033,0.0133896455206493,0.0145773597416208,0.00302465843149228,0.00425899801896098,0.00571037535658025,0.00451670257428749,0.00413169515095307,0.00724907013319539,0.0192237646515783,0.0246292596463586,0.0154244941938109,0.0111050040295891,0.019009169200489,0.0200625582535703,0.0150329514478031,0.0171604781886573,0.00360362454850795,0.00827594251306419,0.0143499519284256,0.013772653828004,0.0174437101214062,0.0173310967771451,0.0216822515219709,0.027636820989289,0.0213478571550886,0.0239486620048229,0.0263346768336037,0.000959214984892561,0.0024086417913891,0.00516079361917281,0.00830590308008967,0.00970316374588394,0.0180028477699621,0.0260691764554236,0.0158490045328198,0.0167909445191476,0.0227140306407696,0.0272022432609499,0.0205998084376832,0.0170442895944108,0.0203935993301381,0.01784039465102,0.0360808411280316,0.00662492535428314,0.0101456826589987,0.0144433042081279,0.0191196406501676,0.0247118082289123,0.0323971654534487,0.0400741522534823,0.0287280791182411,0.0302035258629494,0.0289973432777127,0.0439009717747053,0.0411094886900133,0.0379679844903006,0.00725369791273846,0.0104269286897991,1.72836706726922,1.33581239176055,0.0112169681544413,0.0120555250718954,0.00980455558859136,0.0133931216019476,0.0190558627398586,0.0213918127347246,0.0153962982784459,0.0108248220331717,0.0115967578090896,0.00475090316144902,0.00665362967449798,0.0117070099580525,0.00691775909462176,-0.00171962423628613,0.0339601530665589,0.00832474665785558,0.00551103172420487,0.04163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| |||
|gostat_on_MCL_coexpression=GO:0006810;transport;2.35252618387158e-06;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0051234;establishment of localization;2.72945389052599e-06;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0051179;localization;6.25990538970619e-05;12990,11941,67547,110895,117591,13358,18671,52150,19330,14595,57776,12993,14275,69047,114304,20531,12491,50500,68159,12992,22041!GO:0005988;lactose metabolic process;0.00103749092956346;14595,16770!GO:0046351;disaccharide biosynthetic process;0.00103749092956346;14595,16770!GO:0005989;lactose biosynthetic process;0.00103749092956346;14595,16770!GO:0007595;lactation;0.00108201299969242;20850,11941,102247!GO:0022857;transmembrane transporter activity;0.00165959695027517;57776,11941,67547,110895,117591,20531,114304,13358,69047,18671,52150!GO:0045136;development of secondary sexual characteristics;0.0016946117554734;20850,14595!GO:0005984;disaccharide metabolic process;0.0016946117554734;14595,16770!GO:0004461;lactose synthase activity;0.0016946117554734;14595,16770!GO:0022804;active transmembrane transporter activity;0.00191021098707246;11941,110895,117591,20531,114304,69047,18671!GO:0030879;mammary gland development;0.00194436123413886;20850,102247,14595!GO:0048609;reproductive process in a multicellular organism;0.00257607964279661;20850,11941,102247,14595!GO:0032504;multicellular organism reproduction;0.00257607964279661;20850,11941,102247,14595!GO:0005615;extracellular space;0.00339931704540711;14663,12990,100470,12993,67547,76113,14275,269328,22373,16770,109685,12992,20443,56745,22041!GO:0030855;epithelial cell differentiation;0.0067022668040256;20850,102247,14595!GO:0002064;epithelial cell development;0.00719638305535339;102247,14595!GO:0044421;extracellular region part;0.00784392583037299;14663,12990,100470,12993,67547,76113,14275,269328,22373,16770,109685,12992,20443,56745,22041!GO:0008180;signalosome;0.0108614200215987;12848,26572!GO:0022414;reproductive process;0.0108614200215987;50500,20850,11941,102247,14595!GO:0006812;cation transport;0.0108614200215987;11941,67547,110895,20531,69047,52150,22041!GO:0006811;ion transport;0.0239605402974435;57776,11941,67547,110895,20531,69047,52150,22041!GO:0030001;metal ion transport;0.0261333147095886;11941,67547,110895,20531,52150,22041!GO:0022891;substrate-specific transmembrane transporter activity;0.0270278510339958;57776,11941,67547,117591,20531,114304,69047,52150!GO:0022892;substrate-specific transporter activity;0.0283756944341974;57776,11941,67547,117591,20531,114304,69047,52150,68159!GO:0035250;UDP-galactosyltransferase activity;0.034232902800599;14595,16770!GO:0048732;gland development;0.034232902800599;20850,102247,14595!GO:0015291;secondary active transmembrane transporter activity;0.0405054212757056;110895,117591,20531,114304!GO:0015075;ion transmembrane transporter activity;0.0405054212757056;57776,11941,67547,20531,114304,69047,52150!GO:0003836;beta-galactoside alpha-2,3-sialyltransferase activity;0.0405054212757056;20443!GO:0031527;filopodium membrane;0.0405054212757056;57776!GO:0032433;filopodium tip;0.0405054212757056;57776!GO:0006494;protein amino acid terminal glycosylation;0.0405054212757056;14595!GO:0005345;purine transmembrane transporter activity;0.0405054212757056;114304!GO:0045299;otolith mineralization;0.0405054212757056;11941!GO:0006496;protein amino acid terminal N-glycosylation;0.0405054212757056;14595!GO:0042360;vitamin E metabolic process;0.0405054212757056;50500!GO:0060055;angiogenesis involved in wound healing;0.0405054212757056;14595!GO:0002067;glandular epithelial cell differentiation;0.0405054212757056;102247!GO:0060057;apoptosis involved in mammary gland involution;0.0405054212757056;14595!GO:0042392;sphingosine-1-phosphate phosphatase activity;0.0405054212757056;81535!GO:0060058;positive regulation of apoptosis involved in mammary gland involution;0.0405054212757056;14595!GO:0008431;vitamin E binding;0.0405054212757056;50500!GO:0060054;positive regulation of epithelial cell proliferation involved in wound healing;0.0405054212757056;14595!GO:0015864;pyrimidine nucleoside transport;0.0405054212757056;114304!GO:0046655;folic acid metabolic process;0.0405054212757056;14275!GO:0015389;pyrimidine- and adenine-specific:sodium symporter activity;0.0405054212757056;114304!GO:0015390;purine-specific nucleoside:sodium symporter activity;0.0405054212757056;114304!GO:0060046;regulation of acrosome reaction;0.0405054212757056;14595!GO:0008780;acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity;0.0405054212757056;102247!GO:0002068;glandular epithelial cell development;0.0405054212757056;102247!GO:0008778;acyl-CoA thioesterase II activity;0.0405054212757056;99035!GO:0002071;glandular epithelial cell maturation;0.0405054212757056;102247!GO:0002069;columnar/cuboidal epithelial cell maturation;0.0405054212757056;102247!GO:0008378;galactosyltransferase activity;0.042962597152541;14595,16770!GO:0032787;monocarboxylic acid metabolic process;0.0432121808003774;102247,14275,99035,107476!GO:0019842;vitamin binding;0.0449189028486131;50500,14275,107476! | |||
}} |
Revision as of 11:00, 11 October 2012
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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{{{tfbs_overrepresentation_jaspar}}} |