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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0031323;regulation of cellular metabolic process;0.0330644935547988;21888,12702,17131,214855!GO:0046627;negative regulation of insulin receptor signaling pathway;0.0330644935547988;12702!GO:0019222;regulation of metabolic process;0.0330644935547988;21888,12702,17131,214855!GO:0046626;regulation of insulin receptor signaling pathway;0.0383330540041912;12702!GO:0007167;enzyme linked receptor protein signaling pathway;0.0459795060930929;12702,17131!GO:0007182;common-partner SMAD protein phosphorylation;0.0459795060930929;17131!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0031323;regulation of cellular metabolic process;0.0330644935547988;21888,12702,17131,214855!GO:0046627;negative regulation of insulin receptor signaling pathway;0.0330644935547988;12702!GO:0019222;regulation of metabolic process;0.0330644935547988;21888,12702,17131,214855!GO:0046626;regulation of insulin receptor signaling pathway;0.0383330540041912;12702!GO:0007167;enzyme linked receptor protein signaling pathway;0.0459795060930929;12702,17131!GO:0007182;common-partner SMAD protein phosphorylation;0.0459795060930929;17131!
}}

Revision as of 11:06, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:18890493..18890502,-p@chr10:18890493..18890502
-
Mm9::chr11:106020967..106020992,+p@chr11:106020967..106020992
+
Mm9::chr11:109224378..109224390,+p5@Gna13
Mm9::chr11:109287686..109287703,+p6@Amz2
Mm9::chr11:117830598..117830611,-p5@Socs3
Mm9::chr13:81023987..81024006,-p@chr13:81023987..81024006
-
Mm9::chr14:54842161..54842174,-p@chr14:54842161..54842174
-
Mm9::chr14:79935342..79935383,+p@chr14:79935342..79935383
+
Mm9::chr14:79935384..79935398,+p@chr14:79935384..79935398
+
Mm9::chr14:79935447..79935461,+p@chr14:79935447..79935461
+
Mm9::chr18:68387268..68387287,-p@chr18:68387268..68387287
-
Mm9::chr18:75438577..75438615,+p@chr18:75438577..75438615
+
Mm9::chr18:75439125..75439129,+p@chr18:75439125..75439129
+
Mm9::chr18:75527210..75527215,+p4@Smad7
Mm9::chr19:14672223..14672239,-p3@Tle4
Mm9::chr19:44355454..44355460,+p@chr19:44355454..44355460
+
Mm9::chr19:53387914..53387925,+p@chr19:53387914..53387925
+
Mm9::chr1:36364590..36364608,+p1@Arid5a
Mm9::chr1:53830847..53830858,-p@chr1:53830847..53830858
-
Mm9::chr1:74634691..74634719,-p2@Zfp142
Mm9::chr2:127161597..127161615,-p@chr2:127161597..127161615
-
Mm9::chr2:30567865..30567869,+p@chr2:30567865..30567869
+
Mm9::chr3:30995296..30995300,+p6@Skil
Mm9::chr4:40728877..40728888,-p@chr4:40728877..40728888
-
Mm9::chr4:40728906..40728928,-p@chr4:40728906..40728928
-
Mm9::chr7:97502403..97502441,-p@chr7:97502403..97502441
-
Mm9::chr8:86727420..86727426,-p@chr8:86727420..86727426
-
Mm9::chr9:116084258..116084271,-p3@Tgfbr2
Mm9::chr9:44411777..44411802,+p@chr9:44411777..44411802
+
Mm9::chr9:71958988..71959003,+p@chr9:71958988..71959003
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0031323regulation of cellular metabolic process0.0330644935547988
GO:0046627negative regulation of insulin receptor signaling pathway0.0330644935547988
GO:0019222regulation of metabolic process0.0330644935547988
GO:0046626regulation of insulin receptor signaling pathway0.0383330540041912
GO:0007167enzyme linked receptor protein signaling pathway0.0459795060930929
GO:0007182common-partner SMAD protein phosphorylation0.0459795060930929



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}