MCL coexpression mm9:3172

Phase1 CAGE Peaks

	Short description
Mm9::chr19:11844847..11844896,+	p1@Mrpl16
Mm9::chr8:98412264..98412275,-	p2@Got2
Mm9::chr8:98412277..98412315,-	p1@Got2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004069	aspartate transaminase activity	0.0101585527374333
GO:0044429	mitochondrial part	0.0101585527374333
GO:0000315	organellar large ribosomal subunit	0.0270649807712208
GO:0005762	mitochondrial large ribosomal subunit	0.0270649807712208
GO:0005739	mitochondrion	0.0270649807712208
GO:0008483	transaminase activity	0.0270649807712208
GO:0015934	large ribosomal subunit	0.0270649807712208
GO:0016769	transferase activity, transferring nitrogenous groups	0.0270649807712208
GO:0009058	biosynthetic process	0.0270649807712208
GO:0000313	organellar ribosome	0.0270649807712208
GO:0005761	mitochondrial ribosome	0.0270649807712208
GO:0030170	pyridoxal phosphate binding	0.0281665330698366
GO:0031980	mitochondrial lumen	0.0281665330698366
GO:0005759	mitochondrial matrix	0.0281665330698366
GO:0033279	ribosomal subunit	0.0307453010775401
GO:0006869	lipid transport	0.0343911761270973
GO:0019842	vitamin binding	0.0458887217228312

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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