MCL coexpression mm9:18: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9 | ||
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| ||
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.300884327422511,0.418268492413706,0,0.999594688557941,1.00214672843632,0.915856630888886,0.0354470656487682,0,0,0.170255044926815,0.164001280677683,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.86780554202717,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0,0,0,0,0,0,0,0.0893284091371433,0.858206792018496,0,0,0,0,0,0,0,0,0.0586534975690397,0,0,0.158869788505911,0.171689969376673,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.17540391704926,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0613579207245052,0,0,0,0,0,0,0,0.191523550257637,0,0,0,0,0,0,0,0.0635717028550276,0,0.0642538110976656,0.17364944681578,0.13229915365581,0.110353348438991,0,0,0,0.10582914506561,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.459329101590348,0,0.0737896374598673,0.243899288077882,0.443579783280573,0.485579982245155,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0927069984797182,0,0,0,0,0,0,0,0,0,0,0,0.119259559192106,0,0,0,0,0,0.0492938041367021,0,0.0417740847988257,0.031895734489288,0.041718751492076,0.0403878614760544,0.0398944891531444,0.0480053095083702,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0046649;lymphocyte activation;3.00826150031677e-18;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0042113;B cell activation;4.42309773322479e-18;57916,50723,208154,20947,54125,21939,14025,20963,242248,17060,72049,12482,108723,108655,12518,19264!GO:0045321;leukocyte activation;6.78999478730891e-18;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0001775;cell activation;2.39357988052564e-17;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0002376;immune system process;1.32910707511882e-15;50723,15000,16149,54125,54445,21939,20963,242248,108723,14969,243655,57916,69169,208154,20947,381091,14025,15985,26411,15001,16159,14961,17060,12482,72049,108655,12988,15002,12518,19264,13136!GO:0009897;external side of plasma membrane;3.40282865378507e-12;57916,50723,14128,14961,72049,208154,16149,19264,12518,21939,12483,15985,16401,12478,243655!GO:0006955;immune response;1.56362110611751e-11;57916,50723,69169,208154,20947,16149,54125,54445,21939,381091,15985,20963,16159,14961,72049,108723,108655,15002,19264,12518,13136,14969,243655!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;3.13558548015362e-11;15000,14961,15002,16149,14969,54445,381091,15001!GO:0051249;regulation of lymphocyte activation;3.81385636813417e-11;16159,57916,50723,72049,208154,12988,16149,108723,19264,21939,20963,15001!GO:0051239;regulation of multicellular organismal process;4.84368702656242e-11;57916,50723,208154,16149,54445,21939,15985,20963,15001,16159,72049,108723,12988,108655,12518,19264,13136,243655!GO:0050865;regulation of cell activation;4.84368702656242e-11;16159,57916,50723,72049,208154,12988,16149,108723,19264,21939,20963,15001!GO:0009986;cell surface;1.62569524129376e-10;57916,50723,14128,14961,72049,208154,16149,19264,12518,21939,12483,15985,16401,12478,243655!GO:0019886;antigen processing and presentation of exogenous peptide antigen via MHC class II;4.31554390149814e-10;54445,14969,381091,15000,14961,16149,15001!GO:0002495;antigen processing and presentation of peptide antigen via MHC class II;4.31554390149814e-10;54445,14969,381091,15000,14961,16149,15001!GO:0050863;regulation of T cell activation;8.78290503933659e-10;16159,50723,72049,208154,12988,16149,108723,19264,20963,15001!GO:0002478;antigen processing and presentation of exogenous peptide antigen;1.03879266506589e-09;54445,14969,381091,15000,14961,16149,15001!GO:0032943;mononuclear cell proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,12518,21939,20963!GO:0046651;lymphocyte proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,12518,21939,20963!GO:0050670;regulation of lymphocyte proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,21939,20963!GO:0032944;regulation of mononuclear cell proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,21939,20963!GO:0019884;antigen processing and presentation of exogenous antigen;5.92941983255524e-09;54445,14969,381091,15000,14961,16149,15001!GO:0002764;immune response-regulating signal transduction;6.63080398671776e-09;208154,19264,12518,21939,54445,15985,20963,243655!GO:0002682;regulation of immune system process;1.22387878286737e-08;72049,108655,108723,19264,12518,13136,54445,21939,15985,20963,243655!GO:0042100;B cell proliferation;1.80151542097786e-08;21939,57916,72049,208154,108723,19264,12518!GO:0042110;T cell activation;1.80151542097786e-08;16159,50723,72049,208154,12988,16149,108723,19264,14025,20963,15001!GO:0002520;immune system development;5.5610107073527e-08;50723,20947,108655,16149,108723,19264,54125,12518,21939,14025,20963,26411,15001!GO:0048002;antigen processing and presentation of peptide antigen;9.17813064155732e-08;54445,14969,381091,15000,14961,16149,15001!GO:0002768;immune response-regulating cell surface receptor signaling pathway;9.17813064155732e-08;21939,15985,208154,20963,19264,12518,243655!GO:0030183;B cell differentiation;1.10155030907446e-07;14025,20963,108655,108723,19264,54125,12518!GO:0050671;positive regulation of lymphocyte proliferation;1.25224710102531e-07;16159,21939,50723,72049,20963,108723,19264!GO:0032946;positive regulation of mononuclear cell proliferation;1.25224710102531e-07;16159,21939,50723,72049,20963,108723,19264!GO:0050776;regulation of immune response;1.25224710102531e-07;72049,108723,19264,12518,13136,54445,21939,15985,20963,243655!GO:0044459;plasma membrane part;1.25224710102531e-07;57916,50723,14128,30925,15000,16199,231532,110168,208154,16149,16192,21939,381091,15985,20963,108058,12478,14961,72049,15002,12988,19264,12518,14969,12483,16401,243655!GO:0019882;antigen processing and presentation;1.30306990561222e-07;15000,14961,15002,16149,14969,54445,381091,15001!GO:0042613;MHC class II protein complex;1.71149218148686e-07;14969,381091,15000,14961,15002!GO:0051251;positive regulation of lymphocyte activation;2.14455353342574e-07;16159,21939,50723,72049,20963,16149,108723,19264!GO:0030098;lymphocyte differentiation;3.24366355485805e-07;108655,16149,108723,19264,54125,12518,14025,20963,15001!GO:0042129;regulation of T cell proliferation;3.24366355485805e-07;16159,50723,72049,208154,20963,108723,19264!GO:0050870;positive regulation of T cell activation;3.75406374618431e-07;16159,50723,72049,20963,16149,108723,19264!GO:0002684;positive regulation of immune system process;5.30074822711073e-07;72049,108655,19264,12518,13136,54445,15985,20963,243655!GO:0042102;positive regulation of T cell proliferation;5.569774369727e-07;16159,50723,72049,20963,108723,19264!GO:0002252;immune effector process;6.43621590326196e-07;50723,20947,108655,16149,19264,54125,13136,21939,20963,243655!GO:0050853;B cell receptor signaling pathway;1.64571713876782e-06;15985,20963,19264,12518!GO:0042098;T cell proliferation;1.95998669029136e-06;16159,50723,72049,208154,20963,108723,19264!GO:0051240;positive regulation of multicellular organismal process;2.221803783211e-06;72049,108655,19264,12518,13136,54445,15985,20963,243655!GO:0002757;immune response-activating signal transduction;3.05926941822937e-06;54445,15985,20963,19264,12518,243655!GO:0005886;plasma membrane;3.05926941822937e-06;57916,50723,14128,30925,15000,16199,231532,110168,208154,16149,16192,21939,381091,15985,12493,20963,108058,12478,14961,72049,15002,108723,12988,19264,12518,14969,12483,17086,16401,243655!GO:0005515;protein binding;3.23264578043906e-06;50723,14128,15000,97387,16199,67804,246710,16149,12458,72140,21939,20963,22780,108058,12983,67037,242248,108723,14969,74126,12124,12483,240168,16401,231834,243655,17444,18507,56722,17354,72925,208154,20947,226251,20846,19060,12265,16192,14025,27261,15985,14357,26411,94089,18985,16159,14961,18986,17060,11426,12988,210293,108655,19264,12518,16709,13591!GO:0050864;regulation of B cell activation;3.46424925852782e-06;21939,57916,72049,208154,20963,108723!GO:0002521;leukocyte differentiation;4.05587522158306e-06;108655,16149,108723,19264,54125,12518,14025,20963,15001!GO:0030888;regulation of B cell proliferation;4.84822222076436e-06;21939,57916,72049,208154,108723!GO:0005771;multivesicular body;4.84822222076436e-06;15000,14961,16149,12518!GO:0050778;positive regulation of immune response;5.39002699246448e-06;54445,72049,15985,20963,19264,12518,243655,13136!GO:0002443;leukocyte mediated immunity;6.71626767055559e-06;50723,20947,16149,19264,13136,21939,20963,243655!GO:0048534;hemopoietic or lymphoid organ development;9.27382721442835e-06;108655,16149,108723,19264,54125,12518,14025,20963,26411,15001!GO:0002253;activation of immune response;1.6147054167169e-05;54445,15985,20963,19264,12518,243655,13136!GO:0042611;MHC protein complex;1.68449889693628e-05;14969,381091,15000,14961,15002!GO:0030097;hemopoiesis;2.62789625951439e-05;108655,16149,108723,19264,54125,12518,14025,20963,26411,15001!GO:0016445;somatic diversification of immunoglobulins;2.82663539044761e-05;21939,50723,20947,108655,54125!GO:0048518;positive regulation of biological process;3.76031892124307e-05;50723,226251,54445,21939,15985,20963,16159,18986,72049,108723,108655,12518,19264,13136,12124,13591,243655!GO:0002429;immune response-activating cell surface receptor signaling pathway;3.76031892124307e-05;15985,20963,19264,12518,243655!GO:0002200;somatic diversification of immune receptors;3.76031892124307e-05;21939,50723,20947,108655,54125!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;3.7868851478824e-05;21939,50723,72049,20947,16149,19264,13136!GO:0002250;adaptive immune response;3.7868851478824e-05;21939,50723,72049,20947,16149,19264,13136!GO:0002449;lymphocyte mediated immunity;4.66233104920856e-05;21939,50723,20947,16149,19264,243655,13136!GO:0030217;T cell differentiation;5.38392480514789e-05;14025,20963,16149,108723,19264,15001!GO:0045580;regulation of T cell differentiation;6.81666942702893e-05;20963,16149,108723,15001!GO:0019815;B cell receptor complex;8.95596562032503e-05;15985,20963,12518!GO:0019955;cytokine binding;8.95596562032503e-05;16192,16159,16199,12458,12983!GO:0002377;immunoglobulin production;9.17018886957453e-05;21939,50723,20947,108655,54125!GO:0002440;production of molecular mediator of immune response;0.000102771382485631;21939,50723,20947,108655,54125!GO:0042127;regulation of cell proliferation;0.000144963557618105;16159,57916,50723,72049,208154,108655,12988,108723,19264,21939,20963!GO:0006486;protein amino acid glycosylation;0.000176512047548435;68292,232984,20440,94192,108105,54613!GO:0043413;biopolymer glycosylation;0.000217781399764316;68292,232984,20440,94192,108105,54613!GO:0045619;regulation of lymphocyte differentiation;0.000219586334857838;20963,16149,108723,15001!GO:0009101;glycoprotein biosynthetic process;0.000301711100221081;68292,232984,20440,94192,108105,54613!GO:0008284;positive regulation of cell proliferation;0.00034735119604804;16159,21939,50723,72049,20963,108655,108723,19264!GO:0050871;positive regulation of B cell activation;0.000350940937358895;21939,72049,20963,108723!GO:0050851;antigen receptor-mediated signaling pathway;0.00039465429768804;15985,20963,19264,12518!GO:0005770;late endosome;0.00039465429768804;15000,14961,16149,12518!GO:0016447;somatic recombination of immunoglobulin gene segments;0.00039465429768804;21939,50723,20947,108655!GO:0016444;somatic cell DNA recombination;0.000515827336287108;21939,50723,20947,108655!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.000515827336287108;21939,50723,20947,108655!GO:0009100;glycoprotein metabolic process;0.000654719864765553;68292,232984,20440,94192,108105,54613!GO:0001816;cytokine production;0.000685000649451844;21939,50723,72049,20963,108723,243655!GO:0042108;positive regulation of cytokine biosynthetic process;0.000742059231667869;50723,72049,20963,108723!GO:0008283;cell proliferation;0.000817754994050399;16159,57916,50723,72049,208154,108655,12988,108723,19264,12518,21939,20963!GO:0019814;immunoglobulin complex;0.000955397876073399;15985,20963,12518!GO:0030890;positive regulation of B cell proliferation;0.000955397876073399;21939,72049,108723!GO:0019965;interleukin binding;0.00113759712837907;16192,16159,16199,12983!GO:0016064;immunoglobulin mediated immune response;0.0012553007906246;21939,50723,20947,16149,13136!GO:0019724;B cell mediated immunity;0.0013285768139807;21939,50723,20947,16149,13136!GO:0045727;positive regulation of translation;0.0016728719360457;50723,72049,20963,108723!GO:0045058;T cell selection;0.00210877289587173;20963,16149,108723!GO:0031328;positive regulation of cellular biosynthetic process;0.00217722941034037;50723,72049,20963,108723!GO:0001772;immunological synapse;0.00341090286379491;15985,20963,12518!GO:0042035;regulation of cytokine biosynthetic process;0.00380146471650414;50723,72049,20963,108723!GO:0002208;somatic diversification of immunoglobulins during immune response;0.00380146471650414;21939,50723,20947!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.00380146471650414;21939,50723,20947!GO:0045190;isotype switching;0.00380146471650414;21939,50723,20947!GO:0002381;immunoglobulin production during immune response;0.00433673507288273;21939,50723,20947!GO:0009891;positive regulation of biosynthetic process;0.00456822750477137;50723,72049,20963,108723!GO:0051250;negative regulation of lymphocyte activation;0.00625821716359022;57916,208154,16149!GO:0042089;cytokine biosynthetic process;0.00719532165225802;50723,72049,20963,108723!GO:0042107;cytokine metabolic process;0.00758753662435945;50723,72049,20963,108723!GO:0048731;system development;0.00866136703060087;18507,50723,231532,20947,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,11426,108723,108655,19264,12518,56504,16401!GO:0006464;protein modification process;0.00929770332408216;18507,232984,72925,19060,68292,69740,20963,26411,110948,54613,108058,101540,94192,108105,12988,19264,225638,74126,20440,56504!GO:0008378;galactosyltransferase activity;0.00929770332408216;232984,94192,108105!GO:0048522;positive regulation of cellular process;0.0108266428859257;16159,50723,18986,72049,108655,108723,226251,19264,21939,12124,20963,13591,243655!GO:0002218;activation of innate immune response;0.0112687918009416;54445,243655!GO:0004945;angiotensin type II receptor activity;0.0112687918009416;12458!GO:0001595;angiotensin receptor activity;0.0112687918009416;12458!GO:0030889;negative regulation of B cell proliferation;0.0112687918009416;57916,208154!GO:0002758;innate immune response-activating signal transduction;0.0112687918009416;54445,243655!GO:0065007;biological regulation;0.0115512367949607;50723,232227,16149,54445,21939,20963,22780,67037,70561,242248,108723,74126,12124,240168,243655,57916,18507,56722,208154,226251,20846,12265,14025,236727,15985,26411,15001,16159,18985,18986,72049,11426,108655,12988,269344,12518,19264,13136,16363,116871,13591!GO:0051247;positive regulation of protein metabolic process;0.0121429711749208;50723,72049,20963,108723!GO:0048869;cellular developmental process;0.0123549052620597;18507,56722,231532,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,108723,108655,19264,12518,74126,12124,98752,56504,243655!GO:0030154;cell differentiation;0.0123549052620597;18507,56722,231532,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,108723,108655,19264,12518,74126,12124,98752,56504,243655!GO:0004907;interleukin receptor activity;0.0123549052620597;16192,16199,12983!GO:0043235;receptor complex;0.0123646449182393;15985,20963,16401,12518!GO:0006310;DNA recombination;0.0133691487730524;21939,50723,20947,108655!GO:0046640;regulation of alpha-beta T cell proliferation;0.0133691487730524;208154,20963!GO:0045577;regulation of B cell differentiation;0.0133691487730524;20963,108723!GO:0007242;intracellular signaling cascade;0.0138553527360109;234515,232227,101540,17060,246710,12988,108723,20846,78255,27261,240168,20963,26411,231834,17444!GO:0043412;biopolymer modification;0.0148433925370358;18507,232984,72925,19060,68292,69740,20963,26411,110948,54613,108058,101540,94192,108105,12988,19264,225638,74126,20440,56504!GO:0045088;regulation of innate immune response;0.0159879249343622;54445,243655!GO:0045089;positive regulation of innate immune response;0.0159879249343622;54445,243655!GO:0001782;B cell homeostasis;0.0159879249343622;57916,72049!GO:0050869;negative regulation of B cell activation;0.019009256841078;57916,208154!GO:0046634;regulation of alpha-beta T cell activation;0.019009256841078;208154,20963!GO:0016020;membrane;0.0203145562433311;50723,14128,16199,231532,18703,12458,54445,20963,54613,108058,12983,108105,20440,12483,243958,57916,12763,30925,69169,76438,53374,12478,15001,17060,72049,12482,94192,12988,19264,13136,16709,64380,74096,232984,15000,97387,110168,16149,21939,68292,12493,108723,14969,74126,328833,17086,327957,16401,243655,56722,72925,208154,20947,16192,381091,15985,12494,236727,16205,107993,14961,15002,12518,69106,98256!GO:0045582;positive regulation of T cell differentiation;0.0218758008168219;20963,16149!GO:0001912;positive regulation of leukocyte mediated cytotoxicity;0.0218758008168219;19264,243655!GO:0051085;chaperone cofactor-dependent protein folding;0.0218758008168219;15000,16149!GO:0046633;alpha-beta T cell proliferation;0.0218758008168219;208154,20963!GO:0050789;regulation of biological process;0.0224703791395664;50723,232227,16149,54445,21939,20963,22780,67037,108723,74126,12124,243655,57916,18507,56722,208154,226251,12265,20846,14025,15985,26411,15001,16159,18985,18986,72049,11426,108655,12988,269344,12518,19264,13136,16363,116871,13591!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0259409002390005;20846,19264,12983!GO:0044425;membrane part;0.0284339810397906;74096,50723,14128,15000,232984,16199,231532,110168,18703,16149,54445,21939,68292,12493,20963,54613,108058,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,12988,15002,19264,12518,13136,69106,16709,98256,64380!GO:0051084;'de novo' posttranslational protein folding;0.0284339810397906;15000,16149!GO:0045061;thymic T cell selection;0.0284339810397906;16149,108723!GO:0006458;'de novo' protein folding;0.0284339810397906;15000,16149!GO:0007275;multicellular organismal development;0.0310802132514648;18507,50723,231532,20947,16149,226251,54125,21939,14025,14357,20963,26411,15001,11426,94192,108105,108723,108655,19264,12518,74126,56504,13591,16401!GO:0045621;positive regulation of lymphocyte differentiation;0.0317755059368893;20963,16149!GO:0031341;regulation of cell killing;0.0317755059368893;19264,243655!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.0317755059368893;19264,243655!GO:0016021;integral to membrane;0.0338987925680285;74096,50723,14128,15000,232984,16199,110168,18703,16149,54445,21939,68292,12493,54613,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,15002,19264,12518,13136,69106,16709,98256,64380!GO:0016757;transferase activity, transferring glycosyl groups;0.0343180305506273;68292,232984,20440,94192,108105,54613!GO:0032609;interferon-gamma production;0.0351976775587839;72049,243655!GO:0002699;positive regulation of immune effector process;0.0351976775587839;108655,19264!GO:0031224;intrinsic to membrane;0.0353219198555889;74096,50723,14128,15000,232984,16199,110168,18703,16149,54445,21939,68292,12493,54613,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,15002,19264,12518,13136,69106,16709,98256,64380!GO:0004896;hematopoietin/interferon-class (D200-domain) cytokine receptor activity;0.0373831815511277;16192,16199,12983!GO:0005764;lysosome;0.0373831815511277;17970,56722,15000,15002,16149!GO:0000323;lytic vacuole;0.0373831815511277;17970,56722,15000,15002,16149!GO:0002821;positive regulation of adaptive immune response;0.0373831815511277;72049,19264!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0373831815511277;72049,19264!GO:0050868;negative regulation of T cell activation;0.0373831815511277;208154,16149!GO:0008917;lipopolysaccharide N-acetylglucosaminyltransferase activity;0.0373831815511277;108105!GO:0045610;regulation of hemocyte differentiation;0.0373831815511277;26411!GO:0004164;diphthine synthase activity;0.0373831815511277;69740!GO:0045588;positive regulation of gamma-delta T cell differentiation;0.0373831815511277;20963!GO:0017182;peptidyl-diphthamide metabolic process;0.0373831815511277;69740!GO:0004078;biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity;0.0373831815511277;110948!GO:0005143;interleukin-12 receptor binding;0.0373831815511277;16159!GO:0046645;positive regulation of gamma-delta T cell activation;0.0373831815511277;20963!GO:0051573;negative regulation of histone H3-K9 methylation;0.0373831815511277;18507!GO:0031061;negative regulation of histone methylation;0.0373831815511277;18507!GO:0004633;phosphopantothenoylcysteine decarboxylase activity;0.0373831815511277;66812!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.0373831815511277;19264!GO:0051570;regulation of histone H3-K9 methylation;0.0373831815511277;18507!GO:0016263;glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity;0.0373831815511277;94192!GO:0042386;hemocyte differentiation;0.0373831815511277;26411!GO:0004077;biotin-[acetyl-CoA-carboxylase] ligase activity;0.0373831815511277;110948!GO:0046643;regulation of gamma-delta T cell activation;0.0373831815511277;20963!GO:0030338;CMP-N-acetylneuraminate monooxygenase activity;0.0373831815511277;12763!GO:0017183;peptidyl-diphthamide biosynthetic process from peptidyl-histidine;0.0373831815511277;69740!GO:0016267;O-glycan processing, core 1;0.0373831815511277;94192!GO:0042163;interleukin-12 beta subunit binding;0.0373831815511277;16159!GO:0045586;regulation of gamma-delta T cell differentiation;0.0373831815511277;20963!GO:0030171;voltage-gated proton channel activity;0.0373831815511277;74096!GO:0004502;kynurenine 3-monooxygenase activity;0.0373831815511277;98256!GO:0016266;O-glycan processing;0.0373831815511277;94192!GO:0004080;biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity;0.0373831815511277;110948!GO:0018271;biotin-protein ligase activity;0.0373831815511277;110948!GO:0004079;biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity;0.0373831815511277;110948!GO:0002639;positive regulation of immunoglobulin production;0.0373831815511277;108655!GO:0007165;signal transduction;0.0373831815511277;234515,50723,232227,16199,231532,110168,246710,12458,78255,54445,21939,20963,12983,108723,12483,240168,16401,231834,243655,17444,208154,20846,16192,27261,15985,14357,26411,17060,101540,11426,12482,12988,12518,19264,64380!GO:0002260;lymphocyte homeostasis;0.0387277395624637;57916,72049!GO:0002697;regulation of immune effector process;0.0387277395624637;108655,19264!GO:0050672;negative regulation of lymphocyte proliferation;0.0387277395624637;57916,208154!GO:0032945;negative regulation of mononuclear cell proliferation;0.0387277395624637;57916,208154!GO:0005887;integral to plasma membrane;0.0421865593427613;57916,50723,30925,16199,110168,208154,16149,16192,12483,16401,243655!GO:0001819;positive regulation of cytokine production;0.0421865593427613;21939,243655!GO:0008373;sialyltransferase activity;0.0421865593427613;20440,54613!GO:0048513;organ development;0.0431720201118564;18507,231532,16149,54125,14025,20963,26411,15001,94192,11426,108723,108655,12518,19264,16401,56504!GO:0005085;guanyl-nucleotide exchange factor activity;0.0481026968542056;232227,240168,210293,78255!GO:0031226;intrinsic to plasma membrane;0.0482948223736022;57916,50723,30925,16199,110168,208154,16149,16192,12483,16401,243655!GO:0031325;positive regulation of cellular metabolic process;0.0486098393792459;50723,18986,72049,20963,13591,108723,226251!GO:0005773;vacuole;0.0486098393792459;17970,56722,15000,15002,16149!GO:0002819;regulation of adaptive immune response;0.0486098393792459;72049,19264!GO:0001909;leukocyte mediated cytotoxicity;0.0486098393792459;19264,243655!GO:0001906;cell killing;0.0486098393792459;19264,243655!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0486098393792459;72049,19264! | |gostat_on_MCL_coexpression=GO:0046649;lymphocyte activation;3.00826150031677e-18;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0042113;B cell activation;4.42309773322479e-18;57916,50723,208154,20947,54125,21939,14025,20963,242248,17060,72049,12482,108723,108655,12518,19264!GO:0045321;leukocyte activation;6.78999478730891e-18;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0001775;cell activation;2.39357988052564e-17;57916,50723,208154,20947,16149,54125,21939,14025,20963,15001,16159,242248,17060,72049,12482,108723,12988,108655,19264,12518,243655!GO:0002376;immune system process;1.32910707511882e-15;50723,15000,16149,54125,54445,21939,20963,242248,108723,14969,243655,57916,69169,208154,20947,381091,14025,15985,26411,15001,16159,14961,17060,12482,72049,108655,12988,15002,12518,19264,13136!GO:0009897;external side of plasma membrane;3.40282865378507e-12;57916,50723,14128,14961,72049,208154,16149,19264,12518,21939,12483,15985,16401,12478,243655!GO:0006955;immune response;1.56362110611751e-11;57916,50723,69169,208154,20947,16149,54125,54445,21939,381091,15985,20963,16159,14961,72049,108723,108655,15002,19264,12518,13136,14969,243655!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;3.13558548015362e-11;15000,14961,15002,16149,14969,54445,381091,15001!GO:0051249;regulation of lymphocyte activation;3.81385636813417e-11;16159,57916,50723,72049,208154,12988,16149,108723,19264,21939,20963,15001!GO:0051239;regulation of multicellular organismal process;4.84368702656242e-11;57916,50723,208154,16149,54445,21939,15985,20963,15001,16159,72049,108723,12988,108655,12518,19264,13136,243655!GO:0050865;regulation of cell activation;4.84368702656242e-11;16159,57916,50723,72049,208154,12988,16149,108723,19264,21939,20963,15001!GO:0009986;cell surface;1.62569524129376e-10;57916,50723,14128,14961,72049,208154,16149,19264,12518,21939,12483,15985,16401,12478,243655!GO:0019886;antigen processing and presentation of exogenous peptide antigen via MHC class II;4.31554390149814e-10;54445,14969,381091,15000,14961,16149,15001!GO:0002495;antigen processing and presentation of peptide antigen via MHC class II;4.31554390149814e-10;54445,14969,381091,15000,14961,16149,15001!GO:0050863;regulation of T cell activation;8.78290503933659e-10;16159,50723,72049,208154,12988,16149,108723,19264,20963,15001!GO:0002478;antigen processing and presentation of exogenous peptide antigen;1.03879266506589e-09;54445,14969,381091,15000,14961,16149,15001!GO:0032943;mononuclear cell proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,12518,21939,20963!GO:0046651;lymphocyte proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,12518,21939,20963!GO:0050670;regulation of lymphocyte proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,21939,20963!GO:0032944;regulation of mononuclear cell proliferation;3.84738375357554e-09;16159,57916,50723,72049,208154,108723,19264,21939,20963!GO:0019884;antigen processing and presentation of exogenous antigen;5.92941983255524e-09;54445,14969,381091,15000,14961,16149,15001!GO:0002764;immune response-regulating signal transduction;6.63080398671776e-09;208154,19264,12518,21939,54445,15985,20963,243655!GO:0002682;regulation of immune system process;1.22387878286737e-08;72049,108655,108723,19264,12518,13136,54445,21939,15985,20963,243655!GO:0042100;B cell proliferation;1.80151542097786e-08;21939,57916,72049,208154,108723,19264,12518!GO:0042110;T cell activation;1.80151542097786e-08;16159,50723,72049,208154,12988,16149,108723,19264,14025,20963,15001!GO:0002520;immune system development;5.5610107073527e-08;50723,20947,108655,16149,108723,19264,54125,12518,21939,14025,20963,26411,15001!GO:0048002;antigen processing and presentation of peptide antigen;9.17813064155732e-08;54445,14969,381091,15000,14961,16149,15001!GO:0002768;immune response-regulating cell surface receptor signaling pathway;9.17813064155732e-08;21939,15985,208154,20963,19264,12518,243655!GO:0030183;B cell differentiation;1.10155030907446e-07;14025,20963,108655,108723,19264,54125,12518!GO:0050671;positive regulation of lymphocyte proliferation;1.25224710102531e-07;16159,21939,50723,72049,20963,108723,19264!GO:0032946;positive regulation of mononuclear cell proliferation;1.25224710102531e-07;16159,21939,50723,72049,20963,108723,19264!GO:0050776;regulation of immune response;1.25224710102531e-07;72049,108723,19264,12518,13136,54445,21939,15985,20963,243655!GO:0044459;plasma membrane part;1.25224710102531e-07;57916,50723,14128,30925,15000,16199,231532,110168,208154,16149,16192,21939,381091,15985,20963,108058,12478,14961,72049,15002,12988,19264,12518,14969,12483,16401,243655!GO:0019882;antigen processing and presentation;1.30306990561222e-07;15000,14961,15002,16149,14969,54445,381091,15001!GO:0042613;MHC class II protein complex;1.71149218148686e-07;14969,381091,15000,14961,15002!GO:0051251;positive regulation of lymphocyte activation;2.14455353342574e-07;16159,21939,50723,72049,20963,16149,108723,19264!GO:0030098;lymphocyte differentiation;3.24366355485805e-07;108655,16149,108723,19264,54125,12518,14025,20963,15001!GO:0042129;regulation of T cell proliferation;3.24366355485805e-07;16159,50723,72049,208154,20963,108723,19264!GO:0050870;positive regulation of T cell activation;3.75406374618431e-07;16159,50723,72049,20963,16149,108723,19264!GO:0002684;positive regulation of immune system process;5.30074822711073e-07;72049,108655,19264,12518,13136,54445,15985,20963,243655!GO:0042102;positive regulation of T cell proliferation;5.569774369727e-07;16159,50723,72049,20963,108723,19264!GO:0002252;immune effector process;6.43621590326196e-07;50723,20947,108655,16149,19264,54125,13136,21939,20963,243655!GO:0050853;B cell receptor signaling pathway;1.64571713876782e-06;15985,20963,19264,12518!GO:0042098;T cell proliferation;1.95998669029136e-06;16159,50723,72049,208154,20963,108723,19264!GO:0051240;positive regulation of multicellular organismal process;2.221803783211e-06;72049,108655,19264,12518,13136,54445,15985,20963,243655!GO:0002757;immune response-activating signal transduction;3.05926941822937e-06;54445,15985,20963,19264,12518,243655!GO:0005886;plasma membrane;3.05926941822937e-06;57916,50723,14128,30925,15000,16199,231532,110168,208154,16149,16192,21939,381091,15985,12493,20963,108058,12478,14961,72049,15002,108723,12988,19264,12518,14969,12483,17086,16401,243655!GO:0005515;protein binding;3.23264578043906e-06;50723,14128,15000,97387,16199,67804,246710,16149,12458,72140,21939,20963,22780,108058,12983,67037,242248,108723,14969,74126,12124,12483,240168,16401,231834,243655,17444,18507,56722,17354,72925,208154,20947,226251,20846,19060,12265,16192,14025,27261,15985,14357,26411,94089,18985,16159,14961,18986,17060,11426,12988,210293,108655,19264,12518,16709,13591!GO:0050864;regulation of B cell activation;3.46424925852782e-06;21939,57916,72049,208154,20963,108723!GO:0002521;leukocyte differentiation;4.05587522158306e-06;108655,16149,108723,19264,54125,12518,14025,20963,15001!GO:0030888;regulation of B cell proliferation;4.84822222076436e-06;21939,57916,72049,208154,108723!GO:0005771;multivesicular body;4.84822222076436e-06;15000,14961,16149,12518!GO:0050778;positive regulation of immune response;5.39002699246448e-06;54445,72049,15985,20963,19264,12518,243655,13136!GO:0002443;leukocyte mediated immunity;6.71626767055559e-06;50723,20947,16149,19264,13136,21939,20963,243655!GO:0048534;hemopoietic or lymphoid organ development;9.27382721442835e-06;108655,16149,108723,19264,54125,12518,14025,20963,26411,15001!GO:0002253;activation of immune response;1.6147054167169e-05;54445,15985,20963,19264,12518,243655,13136!GO:0042611;MHC protein complex;1.68449889693628e-05;14969,381091,15000,14961,15002!GO:0030097;hemopoiesis;2.62789625951439e-05;108655,16149,108723,19264,54125,12518,14025,20963,26411,15001!GO:0016445;somatic diversification of immunoglobulins;2.82663539044761e-05;21939,50723,20947,108655,54125!GO:0048518;positive regulation of biological process;3.76031892124307e-05;50723,226251,54445,21939,15985,20963,16159,18986,72049,108723,108655,12518,19264,13136,12124,13591,243655!GO:0002429;immune response-activating cell surface receptor signaling pathway;3.76031892124307e-05;15985,20963,19264,12518,243655!GO:0002200;somatic diversification of immune receptors;3.76031892124307e-05;21939,50723,20947,108655,54125!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;3.7868851478824e-05;21939,50723,72049,20947,16149,19264,13136!GO:0002250;adaptive immune response;3.7868851478824e-05;21939,50723,72049,20947,16149,19264,13136!GO:0002449;lymphocyte mediated immunity;4.66233104920856e-05;21939,50723,20947,16149,19264,243655,13136!GO:0030217;T cell differentiation;5.38392480514789e-05;14025,20963,16149,108723,19264,15001!GO:0045580;regulation of T cell differentiation;6.81666942702893e-05;20963,16149,108723,15001!GO:0019815;B cell receptor complex;8.95596562032503e-05;15985,20963,12518!GO:0019955;cytokine binding;8.95596562032503e-05;16192,16159,16199,12458,12983!GO:0002377;immunoglobulin production;9.17018886957453e-05;21939,50723,20947,108655,54125!GO:0002440;production of molecular mediator of immune response;0.000102771382485631;21939,50723,20947,108655,54125!GO:0042127;regulation of cell proliferation;0.000144963557618105;16159,57916,50723,72049,208154,108655,12988,108723,19264,21939,20963!GO:0006486;protein amino acid glycosylation;0.000176512047548435;68292,232984,20440,94192,108105,54613!GO:0043413;biopolymer glycosylation;0.000217781399764316;68292,232984,20440,94192,108105,54613!GO:0045619;regulation of lymphocyte differentiation;0.000219586334857838;20963,16149,108723,15001!GO:0009101;glycoprotein biosynthetic process;0.000301711100221081;68292,232984,20440,94192,108105,54613!GO:0008284;positive regulation of cell proliferation;0.00034735119604804;16159,21939,50723,72049,20963,108655,108723,19264!GO:0050871;positive regulation of B cell activation;0.000350940937358895;21939,72049,20963,108723!GO:0050851;antigen receptor-mediated signaling pathway;0.00039465429768804;15985,20963,19264,12518!GO:0005770;late endosome;0.00039465429768804;15000,14961,16149,12518!GO:0016447;somatic recombination of immunoglobulin gene segments;0.00039465429768804;21939,50723,20947,108655!GO:0016444;somatic cell DNA recombination;0.000515827336287108;21939,50723,20947,108655!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.000515827336287108;21939,50723,20947,108655!GO:0009100;glycoprotein metabolic process;0.000654719864765553;68292,232984,20440,94192,108105,54613!GO:0001816;cytokine production;0.000685000649451844;21939,50723,72049,20963,108723,243655!GO:0042108;positive regulation of cytokine biosynthetic process;0.000742059231667869;50723,72049,20963,108723!GO:0008283;cell proliferation;0.000817754994050399;16159,57916,50723,72049,208154,108655,12988,108723,19264,12518,21939,20963!GO:0019814;immunoglobulin complex;0.000955397876073399;15985,20963,12518!GO:0030890;positive regulation of B cell proliferation;0.000955397876073399;21939,72049,108723!GO:0019965;interleukin binding;0.00113759712837907;16192,16159,16199,12983!GO:0016064;immunoglobulin mediated immune response;0.0012553007906246;21939,50723,20947,16149,13136!GO:0019724;B cell mediated immunity;0.0013285768139807;21939,50723,20947,16149,13136!GO:0045727;positive regulation of translation;0.0016728719360457;50723,72049,20963,108723!GO:0045058;T cell selection;0.00210877289587173;20963,16149,108723!GO:0031328;positive regulation of cellular biosynthetic process;0.00217722941034037;50723,72049,20963,108723!GO:0001772;immunological synapse;0.00341090286379491;15985,20963,12518!GO:0042035;regulation of cytokine biosynthetic process;0.00380146471650414;50723,72049,20963,108723!GO:0002208;somatic diversification of immunoglobulins during immune response;0.00380146471650414;21939,50723,20947!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.00380146471650414;21939,50723,20947!GO:0045190;isotype switching;0.00380146471650414;21939,50723,20947!GO:0002381;immunoglobulin production during immune response;0.00433673507288273;21939,50723,20947!GO:0009891;positive regulation of biosynthetic process;0.00456822750477137;50723,72049,20963,108723!GO:0051250;negative regulation of lymphocyte activation;0.00625821716359022;57916,208154,16149!GO:0042089;cytokine biosynthetic process;0.00719532165225802;50723,72049,20963,108723!GO:0042107;cytokine metabolic process;0.00758753662435945;50723,72049,20963,108723!GO:0048731;system development;0.00866136703060087;18507,50723,231532,20947,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,11426,108723,108655,19264,12518,56504,16401!GO:0006464;protein modification process;0.00929770332408216;18507,232984,72925,19060,68292,69740,20963,26411,110948,54613,108058,101540,94192,108105,12988,19264,225638,74126,20440,56504!GO:0008378;galactosyltransferase activity;0.00929770332408216;232984,94192,108105!GO:0048522;positive regulation of cellular process;0.0108266428859257;16159,50723,18986,72049,108655,108723,226251,19264,21939,12124,20963,13591,243655!GO:0002218;activation of innate immune response;0.0112687918009416;54445,243655!GO:0004945;angiotensin type II receptor activity;0.0112687918009416;12458!GO:0001595;angiotensin receptor activity;0.0112687918009416;12458!GO:0030889;negative regulation of B cell proliferation;0.0112687918009416;57916,208154!GO:0002758;innate immune response-activating signal transduction;0.0112687918009416;54445,243655!GO:0065007;biological regulation;0.0115512367949607;50723,232227,16149,54445,21939,20963,22780,67037,70561,242248,108723,74126,12124,240168,243655,57916,18507,56722,208154,226251,20846,12265,14025,236727,15985,26411,15001,16159,18985,18986,72049,11426,108655,12988,269344,12518,19264,13136,16363,116871,13591!GO:0051247;positive regulation of protein metabolic process;0.0121429711749208;50723,72049,20963,108723!GO:0048869;cellular developmental process;0.0123549052620597;18507,56722,231532,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,108723,108655,19264,12518,74126,12124,98752,56504,243655!GO:0030154;cell differentiation;0.0123549052620597;18507,56722,231532,16149,226251,54125,21939,14025,14357,20963,26411,15001,94192,108723,108655,19264,12518,74126,12124,98752,56504,243655!GO:0004907;interleukin receptor activity;0.0123549052620597;16192,16199,12983!GO:0043235;receptor complex;0.0123646449182393;15985,20963,16401,12518!GO:0006310;DNA recombination;0.0133691487730524;21939,50723,20947,108655!GO:0046640;regulation of alpha-beta T cell proliferation;0.0133691487730524;208154,20963!GO:0045577;regulation of B cell differentiation;0.0133691487730524;20963,108723!GO:0007242;intracellular signaling cascade;0.0138553527360109;234515,232227,101540,17060,246710,12988,108723,20846,78255,27261,240168,20963,26411,231834,17444!GO:0043412;biopolymer modification;0.0148433925370358;18507,232984,72925,19060,68292,69740,20963,26411,110948,54613,108058,101540,94192,108105,12988,19264,225638,74126,20440,56504!GO:0045088;regulation of innate immune response;0.0159879249343622;54445,243655!GO:0045089;positive regulation of innate immune response;0.0159879249343622;54445,243655!GO:0001782;B cell homeostasis;0.0159879249343622;57916,72049!GO:0050869;negative regulation of B cell activation;0.019009256841078;57916,208154!GO:0046634;regulation of alpha-beta T cell activation;0.019009256841078;208154,20963!GO:0016020;membrane;0.0203145562433311;50723,14128,16199,231532,18703,12458,54445,20963,54613,108058,12983,108105,20440,12483,243958,57916,12763,30925,69169,76438,53374,12478,15001,17060,72049,12482,94192,12988,19264,13136,16709,64380,74096,232984,15000,97387,110168,16149,21939,68292,12493,108723,14969,74126,328833,17086,327957,16401,243655,56722,72925,208154,20947,16192,381091,15985,12494,236727,16205,107993,14961,15002,12518,69106,98256!GO:0045582;positive regulation of T cell differentiation;0.0218758008168219;20963,16149!GO:0001912;positive regulation of leukocyte mediated cytotoxicity;0.0218758008168219;19264,243655!GO:0051085;chaperone cofactor-dependent protein folding;0.0218758008168219;15000,16149!GO:0046633;alpha-beta T cell proliferation;0.0218758008168219;208154,20963!GO:0050789;regulation of biological process;0.0224703791395664;50723,232227,16149,54445,21939,20963,22780,67037,108723,74126,12124,243655,57916,18507,56722,208154,226251,12265,20846,14025,15985,26411,15001,16159,18985,18986,72049,11426,108655,12988,269344,12518,19264,13136,16363,116871,13591!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0259409002390005;20846,19264,12983!GO:0044425;membrane part;0.0284339810397906;74096,50723,14128,15000,232984,16199,231532,110168,18703,16149,54445,21939,68292,12493,20963,54613,108058,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,12988,15002,19264,12518,13136,69106,16709,98256,64380!GO:0051084;'de novo' posttranslational protein folding;0.0284339810397906;15000,16149!GO:0045061;thymic T cell selection;0.0284339810397906;16149,108723!GO:0006458;'de novo' protein folding;0.0284339810397906;15000,16149!GO:0007275;multicellular organismal development;0.0310802132514648;18507,50723,231532,20947,16149,226251,54125,21939,14025,14357,20963,26411,15001,11426,94192,108105,108723,108655,19264,12518,74126,56504,13591,16401!GO:0045621;positive regulation of lymphocyte differentiation;0.0317755059368893;20963,16149!GO:0031341;regulation of cell killing;0.0317755059368893;19264,243655!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.0317755059368893;19264,243655!GO:0016021;integral to membrane;0.0338987925680285;74096,50723,14128,15000,232984,16199,110168,18703,16149,54445,21939,68292,12493,54613,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,15002,19264,12518,13136,69106,16709,98256,64380!GO:0016757;transferase activity, transferring glycosyl groups;0.0343180305506273;68292,232984,20440,94192,108105,54613!GO:0032609;interferon-gamma production;0.0351976775587839;72049,243655!GO:0002699;positive regulation of immune effector process;0.0351976775587839;108655,19264!GO:0031224;intrinsic to membrane;0.0353219198555889;74096,50723,14128,15000,232984,16199,110168,18703,16149,54445,21939,68292,12493,54613,12983,108105,14969,74126,20440,12483,328833,17086,243958,16401,327957,243655,57916,30925,69169,72925,208154,16192,53374,381091,236727,12494,15985,12478,16205,15001,14961,72049,12482,94192,15002,19264,12518,13136,69106,16709,98256,64380!GO:0004896;hematopoietin/interferon-class (D200-domain) cytokine receptor activity;0.0373831815511277;16192,16199,12983!GO:0005764;lysosome;0.0373831815511277;17970,56722,15000,15002,16149!GO:0000323;lytic vacuole;0.0373831815511277;17970,56722,15000,15002,16149!GO:0002821;positive regulation of adaptive immune response;0.0373831815511277;72049,19264!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0373831815511277;72049,19264!GO:0050868;negative regulation of T cell activation;0.0373831815511277;208154,16149!GO:0008917;lipopolysaccharide N-acetylglucosaminyltransferase activity;0.0373831815511277;108105!GO:0045610;regulation of hemocyte differentiation;0.0373831815511277;26411!GO:0004164;diphthine synthase activity;0.0373831815511277;69740!GO:0045588;positive regulation of gamma-delta T cell differentiation;0.0373831815511277;20963!GO:0017182;peptidyl-diphthamide metabolic process;0.0373831815511277;69740!GO:0004078;biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity;0.0373831815511277;110948!GO:0005143;interleukin-12 receptor binding;0.0373831815511277;16159!GO:0046645;positive regulation of gamma-delta T cell activation;0.0373831815511277;20963!GO:0051573;negative regulation of histone H3-K9 methylation;0.0373831815511277;18507!GO:0031061;negative regulation of histone methylation;0.0373831815511277;18507!GO:0004633;phosphopantothenoylcysteine decarboxylase activity;0.0373831815511277;66812!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.0373831815511277;19264!GO:0051570;regulation of histone H3-K9 methylation;0.0373831815511277;18507!GO:0016263;glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity;0.0373831815511277;94192!GO:0042386;hemocyte differentiation;0.0373831815511277;26411!GO:0004077;biotin-[acetyl-CoA-carboxylase] ligase activity;0.0373831815511277;110948!GO:0046643;regulation of gamma-delta T cell activation;0.0373831815511277;20963!GO:0030338;CMP-N-acetylneuraminate monooxygenase activity;0.0373831815511277;12763!GO:0017183;peptidyl-diphthamide biosynthetic process from peptidyl-histidine;0.0373831815511277;69740!GO:0016267;O-glycan processing, core 1;0.0373831815511277;94192!GO:0042163;interleukin-12 beta subunit binding;0.0373831815511277;16159!GO:0045586;regulation of gamma-delta T cell differentiation;0.0373831815511277;20963!GO:0030171;voltage-gated proton channel activity;0.0373831815511277;74096!GO:0004502;kynurenine 3-monooxygenase activity;0.0373831815511277;98256!GO:0016266;O-glycan processing;0.0373831815511277;94192!GO:0004080;biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity;0.0373831815511277;110948!GO:0018271;biotin-protein ligase activity;0.0373831815511277;110948!GO:0004079;biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity;0.0373831815511277;110948!GO:0002639;positive regulation of immunoglobulin production;0.0373831815511277;108655!GO:0007165;signal transduction;0.0373831815511277;234515,50723,232227,16199,231532,110168,246710,12458,78255,54445,21939,20963,12983,108723,12483,240168,16401,231834,243655,17444,208154,20846,16192,27261,15985,14357,26411,17060,101540,11426,12482,12988,12518,19264,64380!GO:0002260;lymphocyte homeostasis;0.0387277395624637;57916,72049!GO:0002697;regulation of immune effector process;0.0387277395624637;108655,19264!GO:0050672;negative regulation of lymphocyte proliferation;0.0387277395624637;57916,208154!GO:0032945;negative regulation of mononuclear cell proliferation;0.0387277395624637;57916,208154!GO:0005887;integral to plasma membrane;0.0421865593427613;57916,50723,30925,16199,110168,208154,16149,16192,12483,16401,243655!GO:0001819;positive regulation of cytokine production;0.0421865593427613;21939,243655!GO:0008373;sialyltransferase activity;0.0421865593427613;20440,54613!GO:0048513;organ development;0.0431720201118564;18507,231532,16149,54125,14025,20963,26411,15001,94192,11426,108723,108655,12518,19264,16401,56504!GO:0005085;guanyl-nucleotide exchange factor activity;0.0481026968542056;232227,240168,210293,78255!GO:0031226;intrinsic to plasma membrane;0.0482948223736022;57916,50723,30925,16199,110168,208154,16149,16192,12483,16401,243655!GO:0031325;positive regulation of cellular metabolic process;0.0486098393792459;50723,18986,72049,20963,13591,108723,226251!GO:0005773;vacuole;0.0486098393792459;17970,56722,15000,15002,16149!GO:0002819;regulation of adaptive immune response;0.0486098393792459;72049,19264!GO:0001909;leukocyte mediated cytotoxicity;0.0486098393792459;19264,243655!GO:0001906;cell killing;0.0486098393792459;19264,243655!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0486098393792459;72049,19264! | ||
}} | }} |
Revision as of 12:35, 11 October 2012
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0046649 | lymphocyte activation | 3.00826150031677e-18 |
GO:0042113 | B cell activation | 4.42309773322479e-18 |
GO:0045321 | leukocyte activation | 6.78999478730891e-18 |
GO:0001775 | cell activation | 2.39357988052564e-17 |
GO:0002376 | immune system process | 1.32910707511882e-15 |
GO:0009897 | external side of plasma membrane | 3.40282865378507e-12 |
GO:0006955 | immune response | 1.56362110611751e-11 |
GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 3.13558548015362e-11 |
GO:0051249 | regulation of lymphocyte activation | 3.81385636813417e-11 |
GO:0051239 | regulation of multicellular organismal process | 4.84368702656242e-11 |
GO:0050865 | regulation of cell activation | 4.84368702656242e-11 |
GO:0009986 | cell surface | 1.62569524129376e-10 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 4.31554390149814e-10 |
GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II | 4.31554390149814e-10 |
GO:0050863 | regulation of T cell activation | 8.78290503933659e-10 |
GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 1.03879266506589e-09 |
GO:0032943 | mononuclear cell proliferation | 3.84738375357554e-09 |
GO:0046651 | lymphocyte proliferation | 3.84738375357554e-09 |
GO:0050670 | regulation of lymphocyte proliferation | 3.84738375357554e-09 |
GO:0032944 | regulation of mononuclear cell proliferation | 3.84738375357554e-09 |
GO:0019884 | antigen processing and presentation of exogenous antigen | 5.92941983255524e-09 |
GO:0002764 | immune response-regulating signal transduction | 6.63080398671776e-09 |
GO:0002682 | regulation of immune system process | 1.22387878286737e-08 |
GO:0042100 | B cell proliferation | 1.80151542097786e-08 |
GO:0042110 | T cell activation | 1.80151542097786e-08 |
GO:0002520 | immune system development | 5.5610107073527e-08 |
GO:0048002 | antigen processing and presentation of peptide antigen | 9.17813064155732e-08 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 9.17813064155732e-08 |
GO:0030183 | B cell differentiation | 1.10155030907446e-07 |
GO:0050671 | positive regulation of lymphocyte proliferation | 1.25224710102531e-07 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 1.25224710102531e-07 |
GO:0050776 | regulation of immune response | 1.25224710102531e-07 |
GO:0044459 | plasma membrane part | 1.25224710102531e-07 |
GO:0019882 | antigen processing and presentation | 1.30306990561222e-07 |
GO:0042613 | MHC class II protein complex | 1.71149218148686e-07 |
GO:0051251 | positive regulation of lymphocyte activation | 2.14455353342574e-07 |
GO:0030098 | lymphocyte differentiation | 3.24366355485805e-07 |
GO:0042129 | regulation of T cell proliferation | 3.24366355485805e-07 |
GO:0050870 | positive regulation of T cell activation | 3.75406374618431e-07 |
GO:0002684 | positive regulation of immune system process | 5.30074822711073e-07 |
GO:0042102 | positive regulation of T cell proliferation | 5.569774369727e-07 |
GO:0002252 | immune effector process | 6.43621590326196e-07 |
GO:0050853 | B cell receptor signaling pathway | 1.64571713876782e-06 |
GO:0042098 | T cell proliferation | 1.95998669029136e-06 |
GO:0051240 | positive regulation of multicellular organismal process | 2.221803783211e-06 |
GO:0002757 | immune response-activating signal transduction | 3.05926941822937e-06 |
GO:0005886 | plasma membrane | 3.05926941822937e-06 |
GO:0005515 | protein binding | 3.23264578043906e-06 |
GO:0050864 | regulation of B cell activation | 3.46424925852782e-06 |
GO:0002521 | leukocyte differentiation | 4.05587522158306e-06 |
GO:0030888 | regulation of B cell proliferation | 4.84822222076436e-06 |
GO:0005771 | multivesicular body | 4.84822222076436e-06 |
GO:0050778 | positive regulation of immune response | 5.39002699246448e-06 |
GO:0002443 | leukocyte mediated immunity | 6.71626767055559e-06 |
GO:0048534 | hemopoietic or lymphoid organ development | 9.27382721442835e-06 |
GO:0002253 | activation of immune response | 1.6147054167169e-05 |
GO:0042611 | MHC protein complex | 1.68449889693628e-05 |
GO:0030097 | hemopoiesis | 2.62789625951439e-05 |
GO:0016445 | somatic diversification of immunoglobulins | 2.82663539044761e-05 |
GO:0048518 | positive regulation of biological process | 3.76031892124307e-05 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 3.76031892124307e-05 |
GO:0002200 | somatic diversification of immune receptors | 3.76031892124307e-05 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 3.7868851478824e-05 |
GO:0002250 | adaptive immune response | 3.7868851478824e-05 |
GO:0002449 | lymphocyte mediated immunity | 4.66233104920856e-05 |
GO:0030217 | T cell differentiation | 5.38392480514789e-05 |
GO:0045580 | regulation of T cell differentiation | 6.81666942702893e-05 |
GO:0019815 | B cell receptor complex | 8.95596562032503e-05 |
GO:0019955 | cytokine binding | 8.95596562032503e-05 |
GO:0002377 | immunoglobulin production | 9.17018886957453e-05 |
GO:0002440 | production of molecular mediator of immune response | 0.000102771382485631 |
GO:0042127 | regulation of cell proliferation | 0.000144963557618105 |
GO:0006486 | protein amino acid glycosylation | 0.000176512047548435 |
GO:0043413 | biopolymer glycosylation | 0.000217781399764316 |
GO:0045619 | regulation of lymphocyte differentiation | 0.000219586334857838 |
GO:0009101 | glycoprotein biosynthetic process | 0.000301711100221081 |
GO:0008284 | positive regulation of cell proliferation | 0.00034735119604804 |
GO:0050871 | positive regulation of B cell activation | 0.000350940937358895 |
GO:0050851 | antigen receptor-mediated signaling pathway | 0.00039465429768804 |
GO:0005770 | late endosome | 0.00039465429768804 |
GO:0016447 | somatic recombination of immunoglobulin gene segments | 0.00039465429768804 |
GO:0016444 | somatic cell DNA recombination | 0.000515827336287108 |
GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 0.000515827336287108 |
GO:0009100 | glycoprotein metabolic process | 0.000654719864765553 |
GO:0001816 | cytokine production | 0.000685000649451844 |
GO:0042108 | positive regulation of cytokine biosynthetic process | 0.000742059231667869 |
GO:0008283 | cell proliferation | 0.000817754994050399 |
GO:0019814 | immunoglobulin complex | 0.000955397876073399 |
GO:0030890 | positive regulation of B cell proliferation | 0.000955397876073399 |
GO:0019965 | interleukin binding | 0.00113759712837907 |
GO:0016064 | immunoglobulin mediated immune response | 0.0012553007906246 |
GO:0019724 | B cell mediated immunity | 0.0013285768139807 |
GO:0045727 | positive regulation of translation | 0.0016728719360457 |
GO:0045058 | T cell selection | 0.00210877289587173 |
GO:0031328 | positive regulation of cellular biosynthetic process | 0.00217722941034037 |
GO:0001772 | immunological synapse | 0.00341090286379491 |
GO:0042035 | regulation of cytokine biosynthetic process | 0.00380146471650414 |
GO:0002208 | somatic diversification of immunoglobulins during immune response | 0.00380146471650414 |
GO:0002204 | somatic recombination of immunoglobulin genes during immune response | 0.00380146471650414 |
GO:0045190 | isotype switching | 0.00380146471650414 |
GO:0002381 | immunoglobulin production during immune response | 0.00433673507288273 |
GO:0009891 | positive regulation of biosynthetic process | 0.00456822750477137 |
GO:0051250 | negative regulation of lymphocyte activation | 0.00625821716359022 |
GO:0042089 | cytokine biosynthetic process | 0.00719532165225802 |
GO:0042107 | cytokine metabolic process | 0.00758753662435945 |
GO:0048731 | system development | 0.00866136703060087 |
GO:0006464 | protein modification process | 0.00929770332408216 |
GO:0008378 | galactosyltransferase activity | 0.00929770332408216 |
GO:0048522 | positive regulation of cellular process | 0.0108266428859257 |
GO:0002218 | activation of innate immune response | 0.0112687918009416 |
GO:0004945 | angiotensin type II receptor activity | 0.0112687918009416 |
GO:0001595 | angiotensin receptor activity | 0.0112687918009416 |
GO:0030889 | negative regulation of B cell proliferation | 0.0112687918009416 |
GO:0002758 | innate immune response-activating signal transduction | 0.0112687918009416 |
GO:0065007 | biological regulation | 0.0115512367949607 |
GO:0051247 | positive regulation of protein metabolic process | 0.0121429711749208 |
GO:0048869 | cellular developmental process | 0.0123549052620597 |
GO:0030154 | cell differentiation | 0.0123549052620597 |
GO:0004907 | interleukin receptor activity | 0.0123549052620597 |
GO:0043235 | receptor complex | 0.0123646449182393 |
GO:0006310 | DNA recombination | 0.0133691487730524 |
GO:0046640 | regulation of alpha-beta T cell proliferation | 0.0133691487730524 |
GO:0045577 | regulation of B cell differentiation | 0.0133691487730524 |
GO:0007242 | intracellular signaling cascade | 0.0138553527360109 |
GO:0043412 | biopolymer modification | 0.0148433925370358 |
GO:0045088 | regulation of innate immune response | 0.0159879249343622 |
GO:0045089 | positive regulation of innate immune response | 0.0159879249343622 |
GO:0001782 | B cell homeostasis | 0.0159879249343622 |
GO:0050869 | negative regulation of B cell activation | 0.019009256841078 |
GO:0046634 | regulation of alpha-beta T cell activation | 0.019009256841078 |
GO:0016020 | membrane | 0.0203145562433311 |
GO:0045582 | positive regulation of T cell differentiation | 0.0218758008168219 |
GO:0001912 | positive regulation of leukocyte mediated cytotoxicity | 0.0218758008168219 |
GO:0051085 | chaperone cofactor-dependent protein folding | 0.0218758008168219 |
GO:0046633 | alpha-beta T cell proliferation | 0.0218758008168219 |
GO:0050789 | regulation of biological process | 0.0224703791395664 |
GO:0019221 | cytokine and chemokine mediated signaling pathway | 0.0259409002390005 |
GO:0044425 | membrane part | 0.0284339810397906 |
GO:0051084 | 'de novo' posttranslational protein folding | 0.0284339810397906 |
GO:0045061 | thymic T cell selection | 0.0284339810397906 |
GO:0006458 | 'de novo' protein folding | 0.0284339810397906 |
GO:0007275 | multicellular organismal development | 0.0310802132514648 |
GO:0045621 | positive regulation of lymphocyte differentiation | 0.0317755059368893 |
GO:0031341 | regulation of cell killing | 0.0317755059368893 |
GO:0001910 | regulation of leukocyte mediated cytotoxicity | 0.0317755059368893 |
GO:0016021 | integral to membrane | 0.0338987925680285 |
GO:0016757 | transferase activity, transferring glycosyl groups | 0.0343180305506273 |
GO:0032609 | interferon-gamma production | 0.0351976775587839 |
GO:0002699 | positive regulation of immune effector process | 0.0351976775587839 |
GO:0031224 | intrinsic to membrane | 0.0353219198555889 |
GO:0004896 | hematopoietin/interferon-class (D200-domain) cytokine receptor activity | 0.0373831815511277 |
GO:0005764 | lysosome | 0.0373831815511277 |
GO:0000323 | lytic vacuole | 0.0373831815511277 |
GO:0002821 | positive regulation of adaptive immune response | 0.0373831815511277 |
GO:0002824 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0373831815511277 |
GO:0050868 | negative regulation of T cell activation | 0.0373831815511277 |
GO:0008917 | lipopolysaccharide N-acetylglucosaminyltransferase activity | 0.0373831815511277 |
GO:0045610 | regulation of hemocyte differentiation | 0.0373831815511277 |
GO:0004164 | diphthine synthase activity | 0.0373831815511277 |
GO:0045588 | positive regulation of gamma-delta T cell differentiation | 0.0373831815511277 |
GO:0017182 | peptidyl-diphthamide metabolic process | 0.0373831815511277 |
GO:0004078 | biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity | 0.0373831815511277 |
GO:0005143 | interleukin-12 receptor binding | 0.0373831815511277 |
GO:0046645 | positive regulation of gamma-delta T cell activation | 0.0373831815511277 |
GO:0051573 | negative regulation of histone H3-K9 methylation | 0.0373831815511277 |
GO:0031061 | negative regulation of histone methylation | 0.0373831815511277 |
GO:0004633 | phosphopantothenoylcysteine decarboxylase activity | 0.0373831815511277 |
GO:0001915 | negative regulation of T cell mediated cytotoxicity | 0.0373831815511277 |
GO:0051570 | regulation of histone H3-K9 methylation | 0.0373831815511277 |
GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | 0.0373831815511277 |
GO:0042386 | hemocyte differentiation | 0.0373831815511277 |
GO:0004077 | biotin-[acetyl-CoA-carboxylase] ligase activity | 0.0373831815511277 |
GO:0046643 | regulation of gamma-delta T cell activation | 0.0373831815511277 |
GO:0030338 | CMP-N-acetylneuraminate monooxygenase activity | 0.0373831815511277 |
GO:0017183 | peptidyl-diphthamide biosynthetic process from peptidyl-histidine | 0.0373831815511277 |
GO:0016267 | O-glycan processing, core 1 | 0.0373831815511277 |
GO:0042163 | interleukin-12 beta subunit binding | 0.0373831815511277 |
GO:0045586 | regulation of gamma-delta T cell differentiation | 0.0373831815511277 |
GO:0030171 | voltage-gated proton channel activity | 0.0373831815511277 |
GO:0004502 | kynurenine 3-monooxygenase activity | 0.0373831815511277 |
GO:0016266 | O-glycan processing | 0.0373831815511277 |
GO:0004080 | biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity | 0.0373831815511277 |
GO:0018271 | biotin-protein ligase activity | 0.0373831815511277 |
GO:0004079 | biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity | 0.0373831815511277 |
GO:0002639 | positive regulation of immunoglobulin production | 0.0373831815511277 |
GO:0007165 | signal transduction | 0.0373831815511277 |
GO:0002260 | lymphocyte homeostasis | 0.0387277395624637 |
GO:0002697 | regulation of immune effector process | 0.0387277395624637 |
GO:0050672 | negative regulation of lymphocyte proliferation | 0.0387277395624637 |
GO:0032945 | negative regulation of mononuclear cell proliferation | 0.0387277395624637 |
GO:0005887 | integral to plasma membrane | 0.0421865593427613 |
GO:0001819 | positive regulation of cytokine production | 0.0421865593427613 |
GO:0008373 | sialyltransferase activity | 0.0421865593427613 |
GO:0048513 | organ development | 0.0431720201118564 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 0.0481026968542056 |
GO:0031226 | intrinsic to plasma membrane | 0.0482948223736022 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0486098393792459 |
GO:0005773 | vacuole | 0.0486098393792459 |
GO:0002819 | regulation of adaptive immune response | 0.0486098393792459 |
GO:0001909 | leukocyte mediated cytotoxicity | 0.0486098393792459 |
GO:0001906 | cell killing | 0.0486098393792459 |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 0.0486098393792459 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |