MCL coexpression mm9:629

Phase1 CAGE Peaks

	Short description
Mm9::chr7:149764044..149764059,-	p2@H19
Mm9::chr7:149839494..149839523,+	p@chr7:149839494..149839523 +
Mm9::chr7:149839544..149839566,+	p@chr7:149839544..149839566 +
Mm9::chr7:149839570..149839604,+	p@chr7:149839570..149839604 +
Mm9::chr7:149839606..149839627,+	p@chr7:149839606..149839627 +
Mm9::chr7:149839638..149839649,+	p@chr7:149839638..149839649 +
Mm9::chr7:149839734..149839750,+	p@chr7:149839734..149839750 +
Mm9::chr7:149839753..149839780,+	p@chr7:149839753..149839780 +
Mm9::chr7:149839897..149839910,+	p@chr7:149839897..149839910 +
Mm9::chr7:149840218..149840258,+	p@chr7:149840218..149840258 +
Mm9::chr7:149841630..149841727,-	p@chr7:149841630..149841727 -
Mm9::chr7:149843377..149843391,-	p1@Igf2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0032879	regulation of localization	0.00300216396179546
GO:0045175	basal protein localization	0.00300216396179546
GO:0030952	establishment and/or maintenance of cytoskeleton polarity	0.00300216396179546
GO:0030950	establishment and/or maintenance of actin cytoskeleton polarity	0.00300216396179546
GO:0032880	regulation of protein localization	0.00300216396179546
GO:0005159	insulin-like growth factor receptor binding	0.00300216396179546
GO:0007509	mesoderm migration	0.00300216396179546
GO:0008078	mesodermal cell migration	0.00300216396179546
GO:0007354	zygotic determination of anterior/posterior axis, embryo	0.00300216396179546
GO:0018445	prothoracicotrophic hormone activity	0.00300216396179546
GO:0048617	embryonic foregut morphogenesis	0.0041693294845452
GO:0010172	embryonic body morphogenesis	0.0041693294845452
GO:0048570	notochord morphogenesis	0.0041693294845452
GO:0008595	determination of anterior/posterior axis, embryo	0.0041693294845452
GO:0007440	foregut morphogenesis	0.0041693294845452
GO:0010171	body morphogenesis	0.0041693294845452
GO:0000578	embryonic axis specification	0.0041693294845452
GO:0007351	tripartite regional subdivision	0.0041693294845452
GO:0048613	embryonic ectodermal gut morphogenesis	0.00428833569223558
GO:0007350	blastoderm segmentation	0.00428833569223558
GO:0048611	embryonic ectodermal gut development	0.00428833569223558
GO:0009887	organ morphogenesis	0.00435714423625449
GO:0030903	notochord development	0.00435714423625449
GO:0045176	apical protein localization	0.00435714423625449
GO:0042074	cell migration involved in gastrulation	0.00435714423625449
GO:0050821	protein stabilization	0.00435714423625449
GO:0048558	embryonic gut morphogenesis	0.00435714423625449
GO:0031647	regulation of protein stability	0.00435714423625449
GO:0048340	paraxial mesoderm morphogenesis	0.00435714423625449
GO:0048557	embryonic digestive tract morphogenesis	0.00435714423625449
GO:0008105	asymmetric protein localization	0.00435714423625449
GO:0007439	ectodermal gut development	0.004547736374749
GO:0048567	ectodermal gut morphogenesis	0.004547736374749
GO:0048547	gut morphogenesis	0.00471652305618482
GO:0009948	anterior/posterior axis specification	0.00471652305618482
GO:0048546	digestive tract morphogenesis	0.00500209879068571
GO:0048339	paraxial mesoderm development	0.00500209879068571
GO:0035050	embryonic heart tube development	0.00500209879068571
GO:0048566	embryonic gut development	0.00500209879068571
GO:0030032	lamellipodium biogenesis	0.00562705272336775
GO:0009798	axis specification	0.00607331131572317
GO:0007492	endoderm development	0.00607331131572317
GO:0048565	gut development	0.00628084476182766
GO:0005184	neuropeptide hormone activity	0.00647892617758477
GO:0048562	embryonic organ morphogenesis	0.00700140307988403
GO:0001707	mesoderm formation	0.0081529139747819
GO:0048332	mesoderm morphogenesis	0.00829839814454409
GO:0001704	formation of primary germ layer	0.00843780333966878
GO:0001756	somitogenesis	0.0101007423278096
GO:0009653	anatomical structure morphogenesis	0.010105950238784
GO:0048568	embryonic organ development	0.0108797608047096
GO:0009880	embryonic pattern specification	0.0115347641465582
GO:0035282	segmentation	0.0118823316942051
GO:0001843	neural tube closure	0.0119396345965588
GO:0014020	primary neural tube formation	0.0122671123223192
GO:0048513	organ development	0.01245056148199
GO:0030031	cell projection biogenesis	0.01245056148199
GO:0007498	mesoderm development	0.01245056148199
GO:0030027	lamellipodium	0.01245056148199
GO:0001841	neural tube formation	0.0134904926600917
GO:0001839	neural plate morphogenesis	0.0135146947329491
GO:0001840	neural plate development	0.013560754755388
GO:0001838	embryonic epithelial tube formation	0.013560754755388
GO:0007369	gastrulation	0.0145178294380388
GO:0021915	neural tube development	0.0149849128520706
GO:0016331	morphogenesis of embryonic epithelium	0.016357140712145
GO:0048731	system development	0.016357140712145
GO:0048729	tissue morphogenesis	0.0165001390659627
GO:0031252	leading edge	0.0165001390659627
GO:0009952	anterior/posterior pattern formation	0.0201065831168786
GO:0048856	anatomical structure development	0.0209856892116161
GO:0001701	in utero embryonic development	0.0243912619149578
GO:0005179	hormone activity	0.0243912619149578
GO:0002009	morphogenesis of an epithelium	0.0248677111669075
GO:0007275	multicellular organismal development	0.0248872919805833
GO:0003002	regionalization	0.0285590405921332
GO:0035239	tube morphogenesis	0.0285590405921332
GO:0008083	growth factor activity	0.0285590405921332
GO:0030036	actin cytoskeleton organization and biogenesis	0.0291397516052694
GO:0030029	actin filament-based process	0.0308215683151415
GO:0007507	heart development	0.0313591960542605
GO:0048646	anatomical structure formation	0.0338773029091021
GO:0048598	embryonic morphogenesis	0.0357229325154513
GO:0035295	tube development	0.0357229325154513
GO:0016337	cell-cell adhesion	0.0365250647035108
GO:0032502	developmental process	0.0375818806547521
GO:0043009	chordate embryonic development	0.0379021662822594
GO:0009792	embryonic development ending in birth or egg hatching	0.0379769819609002
GO:0007389	pattern specification process	0.0392158139374696
GO:0032990	cell part morphogenesis	0.0432477490115378
GO:0048858	cell projection morphogenesis	0.0432477490115378
GO:0030030	cell projection organization and biogenesis	0.0432477490115378
GO:0016477	cell migration	0.0437368860730111
GO:0009888	tissue development	0.0445297979675441

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}