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MCL coexpression mm9:146: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002369!2.40e-74!7;UBERON:0006858!2.40e-74!7;UBERON:0003064!1.49e-37!14;UBERON:0005256!4.78e-12!45;UBERON:0005172!4.27e-11!49;UBERON:0005173!4.27e-11!49;UBERON:0002417!4.27e-11!49;UBERON:0000916!4.27e-11!49;UBERON:0002368!3.96e-09!60;UBERON:0003104!5.52e-09!61;UBERON:0009142!5.52e-09!61;UBERON:0002530!1.88e-08!65;UBERON:0009569!2.50e-08!66;UBERON:0000949!1.17e-07!72;UBERON:0005177!5.28e-07!79
|ontology_enrichment_uberon=UBERON:0002369!2.40e-74!7;UBERON:0006858!2.40e-74!7;UBERON:0003064!1.49e-37!14;UBERON:0005256!4.78e-12!45;UBERON:0005172!4.27e-11!49;UBERON:0005173!4.27e-11!49;UBERON:0002417!4.27e-11!49;UBERON:0000916!4.27e-11!49;UBERON:0002368!3.96e-09!60;UBERON:0003104!5.52e-09!61;UBERON:0009142!5.52e-09!61;UBERON:0002530!1.88e-08!65;UBERON:0009569!2.50e-08!66;UBERON:0000949!1.17e-07!72;UBERON:0005177!5.28e-07!79
|tfbs_overrepresentation_for_novel_motifs=0.2448,0.00836285,0.0413035,0.0843886,0.181918,0.0326197,0.188747,0.192511,0.0866141,0.0423143,0.0508948,0.345138,0.0728592,0.0798205,1.72773,0,0.237279,0.0933066,0.323143,0.318814,0.386269,0.231725,0.0792935,2.90956,0.353011,0.239814,2.28804,0.240106,0.0162654,0.193485,0.0349811,0.713885,1.18311,0.398899,0.0293769,0.044703,0.0381632,0.0644755,0.175218,0.0323507,0.764862,0.397835,1.15554,0.505634,0.00611775,0.169154,0.0418043,0.0465099,0.811741,0.1009,0.219558,0.822678,0.239524,0.540552,1.07511,0.409589,1.48402,0.160059,0.345535,0.210293,0.0995356,0.0296263,0.106416,0.0571113,0.0206377,0.24957,0.283598,0.560216,0.32199,0.437083,0.0818346,0.135927,6.57028e-05,0.214856,0.00064746,0.0226391,0.0877536,0.350687,0.307387,0.143433,1.63905,0.255525,0.121123,0.0638867,0.147288,5.55679e-08,3.74878e-05,1.12067,0.165992,0.703643,1.59537,0.14997,0.114631,0.82877,0.000509513,1.43047,0.671333,0.115971,0.161975,0.336191,3.00978,0.713291,1.57587,0.220151,0.2191,0.0366678,0.591692,0.99178,0.150737,0.139859,0.384765,0.174479,0.00755193,0.010771,0.899989,0.169465,0.00162106,0.190471,0.0674403,0.845959,0.218281,0.738592,0.242296,0.0385355,0.380615,0.0936555,0.385955,0.111428,0.772145,0.117117,0.952648,0.174534,0.262047,0.230751,0.355631,0.0325378,3.70768,0.401338,0.318925,1.04798,0.674956,0.286919,0.0249343,0.736232,0.465415,0.226256,0.164446,1.01005,1.21015,0.0537783,0.284717,1.8143e-05,0.184571,0.460457,0.711228,2.6921,1.62673,0.149247,0.126315,0.0189259,0.325921,0.449878,0.312198,0.118383,0.209461,1.39952,0.0774985,0.0655253,1.62115e-06
}}
}}

Revision as of 17:52, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:25798660..25798671,-p3@Tmem200a
Mm9::chr11:100562725..100562761,-p@chr11:100562725..100562761
-
Mm9::chr11:44776406..44776412,+p@chr11:44776406..44776412
+
Mm9::chr11:44776431..44776437,+p@chr11:44776431..44776437
+
Mm9::chr11:44776438..44776448,+p@chr11:44776438..44776448
+
Mm9::chr11:49961417..49961419,+p7@Tbc1d9b
Mm9::chr11:56083454..56083465,-p@chr11:56083454..56083465
-
Mm9::chr11:69144867..69144875,+p@chr11:69144867..69144875
+
Mm9::chr11:75661198..75661204,-p@chr11:75661198..75661204
-
Mm9::chr11:97385219..97385229,-p@chr11:97385219..97385229
-
Mm9::chr11:97385234..97385248,-p@chr11:97385234..97385248
-
Mm9::chr11:97386778..97386788,-p@chr11:97386778..97386788
-
Mm9::chr12:103792439..103792469,+p@chr12:103792439..103792469
+
Mm9::chr12:112936826..112936835,+p@chr12:112936826..112936835
+
Mm9::chr12:112936844..112936851,+p@chr12:112936844..112936851
+
Mm9::chr12:112936852..112936860,+p@chr12:112936852..112936860
+
Mm9::chr12:26066824..26066837,+p@chr12:26066824..26066837
+
Mm9::chr12:29808161..29808203,+p@chr12:29808161..29808203
+
Mm9::chr14:54873434..54873445,-p@chr14:54873434..54873445
-
Mm9::chr15:74672231..74672246,-p2@Cyp11b1
Mm9::chr15:74686657..74686666,-p1@Cyp11b2
Mm9::chr15:74686669..74686674,-p2@Cyp11b2
Mm9::chr15:78832682..78832693,+p@chr15:78832682..78832693
+
Mm9::chr15:78832710..78832726,+p@chr15:78832710..78832726
+
Mm9::chr15:78832728..78832746,+p@chr15:78832728..78832746
+
Mm9::chr15:97654059..97654071,-p@chr15:97654059..97654071
-
Mm9::chr15:99541184..99541206,+p@chr15:99541184..99541206
+
Mm9::chr16:20622397..20622408,-p@chr16:20622397..20622408
-
Mm9::chr17:74366037..74366061,+p@chr17:74366037..74366061
+
Mm9::chr17:74366177..74366185,-p@chr17:74366177..74366185
-
Mm9::chr17:74366240..74366253,-p@chr17:74366240..74366253
-
Mm9::chr17:74366267..74366274,-p@chr17:74366267..74366274
-
Mm9::chr17:74366314..74366359,+p@chr17:74366314..74366359
+
Mm9::chr17:74366338..74366346,-p@chr17:74366338..74366346
-
Mm9::chr17:74366380..74366381,-p@chr17:74366380..74366381
-
Mm9::chr17:74366410..74366417,-p@chr17:74366410..74366417
-
Mm9::chr17:74366441..74366450,-p@chr17:74366441..74366450
-
Mm9::chr17:74366483..74366490,-p@chr17:74366483..74366490
-
Mm9::chr17:74366539..74366548,-p@chr17:74366539..74366548
-
Mm9::chr17:74366695..74366701,-p@chr17:74366695..74366701
-
Mm9::chr17:74366801..74366811,-p@chr17:74366801..74366811
-
Mm9::chr17:74370799..74370822,-p@chr17:74370799..74370822
-
Mm9::chr17:74397190..74397207,-p1@Srd5a2
Mm9::chr18:57711991..57712002,-p2@4930511M06Rik
Mm9::chr18:57712022..57712069,-p1@4930511M06Rik
Mm9::chr1:134195879..134195889,+p@chr1:134195879..134195889
+
Mm9::chr1:191226627..191226640,-p11@Kcnk2
Mm9::chr1:87853313..87853322,-p@chr1:87853313..87853322
-
Mm9::chr1:87854137..87854148,+p@chr1:87854137..87854148
+
Mm9::chr2:132606442..132606466,+p@chr2:132606442..132606466
+
Mm9::chr2:65172367..65172377,+p@chr2:65172367..65172377
+
Mm9::chr2:65172380..65172388,+p@chr2:65172380..65172388
+
Mm9::chr3:20266092..20266106,-p1@Agtr1b
Mm9::chr3:60332432..60332443,+p24@Mbnl1
Mm9::chr3:98686082..98686093,-p@chr3:98686082..98686093
-
Mm9::chr4:119006224..119006237,-p@chr4:119006224..119006237
-
Mm9::chr4:54203029..54203059,-p@chr4:54203029..54203059
-
Mm9::chr5:103945145..103945156,+p@chr5:103945145..103945156
+
Mm9::chr5:112678344..112678360,-p@chr5:112678344..112678360
-
Mm9::chr5:30924826..30924840,+p@chr5:30924826..30924840
+
Mm9::chr5:30924877..30924900,+p@chr5:30924877..30924900
+
Mm9::chr6:28425101..28425121,+p4@Snd1
Mm9::chr6:67441843..67441856,-p1@Il23r
Mm9::chr6:90515931..90515963,+p@chr6:90515931..90515963
+
Mm9::chr7:25773155..25773172,-p@chr7:25773155..25773172
-
Mm9::chr7:29103937..29103978,-p@chr7:29103937..29103978
-
Mm9::chr7:53197606..53197611,+p@chr7:53197606..53197611
+
Mm9::chr7:53197617..53197631,+p@chr7:53197617..53197631
+
Mm9::chr7:53197649..53197662,+p@chr7:53197649..53197662
+
Mm9::chr7:53197663..53197668,+p@chr7:53197663..53197668
+
Mm9::chr7:57150972..57150982,+p@chr7:57150972..57150982
+
Mm9::chr8:26918720..26918722,-p@chr8:26918720..26918722
-
Mm9::chr8:46641086..46641089,-p@chr8:46641086..46641089
-
Mm9::chr8:46641091..46641099,-p@chr8:46641091..46641099
-
Mm9::chr9:113702099..113702110,+p13@Clasp2
Mm9::chr9:113702146..113702187,+p10@Clasp2
Mm9::chrX:133893233..133893244,+p@chrX:133893233..133893244
+
Mm9::chrX:133893268..133893277,+p@chrX:133893268..133893277
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0047783corticosterone 18-monooxygenase activity0.000131939079804341
GO:0042446hormone biosynthetic process0.000254948009654592
GO:0016713oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen0.000263589100847798
GO:0042756drinking behavior0.000263589100847798
GO:0001991regulation of systemic arterial blood pressure by circulatory renin-angiotensin0.000263589100847798
GO:0003081regulation of systemic arterial blood pressure by renin-angiotensin0.00052803196641909
GO:0006694steroid biosynthetic process0.00052803196641909
GO:0042445hormone metabolic process0.000723282848417456
GO:0050886endocrine process0.000723282848417456
GO:0001990regulation of systemic arterial blood pressure by hormone0.000723282848417456
GO:0003044regulation of systemic arterial blood pressure mediated by a chemical signal0.00162233206126697
GO:0003073regulation of systemic arterial blood pressure0.00236578536726
GO:0008202steroid metabolic process0.00236578536726
GO:0007631feeding behavior0.00522554161663299
GO:0008217regulation of blood pressure0.00676624913231487
GO:0008610lipid biosynthetic process0.00896387150052773
GO:0030322stabilization of membrane potential0.00912178819920013
GO:0042020interleukin-23 receptor activity0.00912178819920013
GO:0042019interleukin-23 binding0.00912178819920013
GO:0001977renal regulation of blood volume0.00912178819920013
GO:0002017aldosterone mediated regulation of blood volume0.00912178819920013
GO:0004507steroid 11-beta-monooxygenase activity0.00912178819920013
GO:0006705mineralocorticoid biosynthetic process0.00912178819920013
GO:0032342aldosterone biosynthetic process0.00912178819920013
GO:0032341aldosterone metabolic process0.015093582568338
GO:00038653-oxo-5-alpha-steroid 4-dehydrogenase activity0.015093582568338
GO:0008212mineralocorticoid metabolic process0.015093582568338
GO:0001596angiotensin type I receptor activity0.015093582568338
GO:0006702androgen biosynthetic process0.015093582568338
GO:0008015blood circulation0.0183687885647461
GO:0003013circulatory system process0.0183687885647461
GO:0003071renal regulation of systemic arterial blood pressure0.0257323624051305
GO:0008250oligosaccharyl transferase complex0.0257323624051305
GO:0008209androgen metabolic process0.0257323624051305
GO:0004497monooxygenase activity0.0271557959740367
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0271557959740367
GO:0006704glucocorticoid biosynthetic process0.0287709451537365
GO:0004947bradykinin receptor activity0.0287709451537365
GO:0044255cellular lipid metabolic process0.0319892648727216
GO:0030539male genitalia development0.0319892648727216
GO:0005881cytoplasmic microtubule0.0319892648727216
GO:0005792microsome0.0339931605720481
GO:0042598vesicular fraction0.0339931605720481
GO:0004576oligosaccharyl transferase activity0.0339931605720481
GO:0004579dolichyl-diphosphooligosaccharide-protein glycotransferase activity0.0339931605720481
GO:0009058biosynthetic process0.0356672058334092
GO:0050801ion homeostasis0.0356672058334092
GO:0004945angiotensin type II receptor activity0.0356672058334092
GO:0001595angiotensin receptor activity0.0356672058334092
GO:0065007biological regulation0.0356844298370584
GO:0006629lipid metabolic process0.0370860851347921
GO:0008211glucocorticoid metabolic process0.0370860851347921
GO:0003084positive regulation of systemic arterial blood pressure0.0370860851347921
GO:0065008regulation of biological quality0.0383035188895647
GO:0031114regulation of microtubule depolymerization0.0383035188895647
GO:0008395steroid hydroxylase activity0.0383035188895647
GO:0007026negative regulation of microtubule depolymerization0.0383035188895647
GO:0048806genitalia development0.0393591369102827
GO:0031111negative regulation of microtubule polymerization or depolymerization0.0393591369102827
GO:0007019microtubule depolymerization0.0393591369102827
GO:0045777positive regulation of blood pressure0.0393591369102827
GO:0005737cytoplasm0.0417073529216181
GO:0048878chemical homeostasis0.0418185180624226
GO:0006376mRNA splice site selection0.0436265741508196
GO:0031110regulation of microtubule polymerization or depolymerization0.0436265741508196
GO:0031109microtubule polymerization or depolymerization0.0448961861337184
GO:0006700C21-steroid hormone biosynthetic process0.0448961861337184
GO:0003014renal system process0.0448961861337184



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adrenal gland2.40e-747
adrenal/interrenal gland2.40e-747
intermediate mesoderm1.49e-3714
trunk mesenchyme4.78e-1245
abdomen element4.27e-1149
abdominal segment element4.27e-1149
abdominal segment of trunk4.27e-1149
abdomen4.27e-1149
endocrine gland3.96e-0960
mesenchyme5.52e-0961
entire embryonic mesenchyme5.52e-0961
gland1.88e-0865
subdivision of trunk2.50e-0866
endocrine system1.17e-0772
trunk region element5.28e-0779


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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