MCL coexpression mm9:2857

Phase1 CAGE Peaks

	Short description
Mm9::chr13:53381421..53381498,-	p1@Ror2
Mm9::chr13:53381564..53381582,-	p2@Ror2
Mm9::chr15:103197201..103197229,-	p2@Itga5

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016337	cell-cell adhesion	0.00977867858707255
GO:0030538	embryonic genitalia morphogenesis	0.00977867858707255
GO:0035112	genitalia morphogenesis	0.00977867858707255
GO:0033631	cell-cell adhesion mediated by integrin	0.00977867858707255
GO:0007044	cell-substrate junction assembly	0.0108646031093623
GO:0033627	cell adhesion mediated by integrin	0.0108646031093623
GO:0022610	biological adhesion	0.0130353805766488
GO:0007155	cell adhesion	0.0130353805766488
GO:0001502	cartilage condensation	0.0130353805766488
GO:0007159	leukocyte adhesion	0.0130353805766488
GO:0048806	genitalia development	0.0130353805766488
GO:0007613	memory	0.0150890490588407
GO:0007028	cytoplasm organization and biogenesis	0.0150890490588407
GO:0005887	integral to plasma membrane	0.0150890490588407
GO:0031226	intrinsic to plasma membrane	0.0150890490588407
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	0.0150890490588407
GO:0048562	embryonic organ morphogenesis	0.0150890490588407
GO:0007157	heterophilic cell adhesion	0.0150890490588407
GO:0005178	integrin binding	0.0150890490588407
GO:0001756	somitogenesis	0.0210916007202392
GO:0008305	integrin complex	0.0210916007202392
GO:0048568	embryonic organ development	0.0219075210098814
GO:0035282	segmentation	0.0233345778337855
GO:0007254	JNK cascade	0.0233345778337855
GO:0031098	stress-activated protein kinase signaling pathway	0.0236321687388623
GO:0051216	cartilage development	0.0236321687388623
GO:0032403	protein complex binding	0.0236321687388623
GO:0019717	synaptosome	0.0241813662758165
GO:0044459	plasma membrane part	0.0262728581673572
GO:0004714	transmembrane receptor protein tyrosine kinase activity	0.0269021384428476
GO:0007611	learning and/or memory	0.0279401802691967
GO:0043235	receptor complex	0.0279401802691967
GO:0007548	sex differentiation	0.0279401802691967
GO:0019199	transmembrane receptor protein kinase activity	0.0279401802691967
GO:0003006	reproductive developmental process	0.0319639668117684
GO:0007229	integrin-mediated signaling pathway	0.0328783130993726
GO:0009952	anterior/posterior pattern formation	0.033041593482659
GO:0005886	plasma membrane	0.0336303441636246
GO:0000165	MAPKKK cascade	0.0393131704629499
GO:0016055	Wnt receptor signaling pathway	0.0393131704629499
GO:0009897	external side of plasma membrane	0.0430912070023746
GO:0003002	regionalization	0.0454538084211183
GO:0004713	protein-tyrosine kinase activity	0.047403888037922
GO:0007166	cell surface receptor linked signal transduction	0.04902714526475

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>

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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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