Novel motif:15

name:	motif15_ACTGTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	5.592997e-53
GO:0006952	defense response	1.520086e-38
GO:0002376	immune system process	1.109067e-36
GO:0006955	immune response	5.066833e-35
GO:0065007	biological regulation	3.827205e-32
GO:0051716	cellular response to stimulus	4.978166e-32
GO:0050789	regulation of biological process	2.460384e-31
GO:0007154	cell communication	2.404335e-27
GO:0023052	signaling	1.044851e-26
GO:0009607	response to biotic stimulus	1.830498e-26
GO:0007165	signal transduction	7.464532e-26
GO:0006950	response to stress	2.163656e-25
GO:0032501	multicellular organismal process	3.653145e-25
GO:0048583	regulation of response to stimulus	1.719428e-24
GO:0051707	response to other organism	2.506841e-24
GO:0050794	regulation of cellular process	4.420804e-24
GO:0006954	inflammatory response	6.375586e-24
GO:0045087	innate immune response	1.737259e-23
GO:0009987	cellular process	1.554986e-22
GO:0009617	response to bacterium	8.821971e-20
GO:0007166	cell surface receptor linked signaling pathway	2.596457e-19
GO:0002253	activation of immune response	2.687795e-19
GO:0002684	positive regulation of immune system process	4.843380e-19
GO:0042221	response to chemical stimulus	1.451304e-18
GO:0050778	positive regulation of immune response	1.591989e-18
GO:0009611	response to wounding	1.759903e-18
GO:0002237	response to molecule of bacterial origin	2.126819e-18
GO:0051704	multi-organism process	3.390066e-18
GO:0032496	response to lipopolysaccharide	8.737480e-18
GO:0002682	regulation of immune system process	9.295317e-18
GO:0065008	regulation of biological quality	1.748857e-17
GO:0044281	small molecule metabolic process	9.136719e-17
GO:0051234	establishment of localization	1.250287e-16
GO:0006810	transport	2.219442e-16
GO:0050776	regulation of immune response	2.384622e-16
GO:0048584	positive regulation of response to stimulus	2.592334e-16
GO:0032879	regulation of localization	4.359031e-16
GO:0080134	regulation of response to stress	8.019677e-16
GO:0010033	response to organic substance	8.127683e-16
GO:0009628	response to abiotic stimulus	2.149006e-15
GO:0002757	immune response-activating signal transduction	2.640269e-15
GO:0001775	cell activation	3.790843e-15
GO:0051179	localization	4.673477e-15
GO:0002764	immune response-regulating signaling pathway	4.684345e-15
GO:0008152	metabolic process	5.542588e-15
GO:0048518	positive regulation of biological process	1.353862e-14
GO:0051050	positive regulation of transport	1.446240e-14
GO:0032502	developmental process	5.241326e-14
GO:0045321	leukocyte activation	8.102961e-14
GO:0007155	cell adhesion	2.009774e-13
GO:0051049	regulation of transport	2.517738e-13
GO:0006968	cellular defense response	2.648075e-13
GO:0006725	cellular aromatic compound metabolic process	3.837363e-13
GO:0051239	regulation of multicellular organismal process	9.773619e-13
GO:0042592	homeostatic process	2.510801e-12
GO:0048519	negative regulation of biological process	3.342593e-12
GO:0006875	cellular metal ion homeostasis	4.135951e-12
GO:0030003	cellular cation homeostasis	4.964352e-12
GO:0006629	lipid metabolic process	6.047559e-12
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	6.361953e-12
GO:0055065	metal ion homeostasis	7.133176e-12
GO:2000021	regulation of ion homeostasis	7.517181e-12
GO:0042326	negative regulation of phosphorylation	7.755772e-12
GO:0016192	vesicle-mediated transport	8.186196e-12
GO:0051240	positive regulation of multicellular organismal process	9.829713e-12
GO:0048856	anatomical structure development	1.103715e-11
GO:0042446	hormone biosynthetic process	1.121899e-11
GO:0045936	negative regulation of phosphate metabolic process	1.162701e-11
GO:0031347	regulation of defense response	1.651582e-11
GO:0019538	protein metabolic process	1.696928e-11
GO:0009268	response to pH	1.953531e-11
GO:0030799	regulation of cyclic nucleotide metabolic process	2.102528e-11
GO:0032844	regulation of homeostatic process	2.251003e-11
GO:0071840	cellular component organization or biogenesis	2.608373e-11
GO:0010646	regulation of cell communication	2.704445e-11
GO:0007267	cell-cell signaling	2.792441e-11
GO:0030802	regulation of cyclic nucleotide biosynthetic process	3.077876e-11
GO:0007186	G-protein coupled receptor protein signaling pathway	3.087802e-11
GO:0034097	response to cytokine stimulus	3.511621e-11
GO:0031295	T cell costimulation	5.353136e-11
GO:0007275	multicellular organismal development	5.656125e-11
GO:0031279	regulation of cyclase activity	6.520658e-11
GO:0051223	regulation of protein transport	7.206424e-11
GO:0070887	cellular response to chemical stimulus	8.347502e-11
GO:0044106	cellular amine metabolic process	1.020555e-10
GO:0006873	cellular ion homeostasis	1.063536e-10
GO:0051339	regulation of lyase activity	1.159749e-10
GO:0016043	cellular component organization	1.170303e-10
GO:0023051	regulation of signaling	1.173670e-10
GO:0060333	interferon-gamma-mediated signaling pathway	1.567693e-10
GO:0032940	secretion by cell	1.984712e-10
GO:0071222	cellular response to lipopolysaccharide	3.253512e-10
GO:0046649	lymphocyte activation	3.957840e-10
GO:0046777	protein autophosphorylation	4.873647e-10
GO:0009966	regulation of signal transduction	5.962137e-10
GO:0030814	regulation of cAMP metabolic process	6.002084e-10
GO:0048523	negative regulation of cellular process	6.399150e-10
GO:0031641	regulation of myelination	7.501352e-10
GO:0031663	lipopolysaccharide-mediated signaling pathway	9.803280e-10
GO:0055082	cellular chemical homeostasis	1.018084e-9
GO:0045056	transcytosis	1.105998e-9
GO:0019725	cellular homeostasis	1.254631e-9
GO:0071346	cellular response to interferon-gamma	1.335618e-9
GO:0071219	cellular response to molecule of bacterial origin	1.430382e-9
GO:0009308	amine metabolic process	1.505489e-9
GO:0071216	cellular response to biotic stimulus	1.598862e-9
GO:0006066	alcohol metabolic process	1.839431e-9
GO:0048513	organ development	2.289595e-9
GO:0002576	platelet degranulation	2.480070e-9
GO:0048878	chemical homeostasis	2.482421e-9
GO:0050801	ion homeostasis	2.627277e-9
GO:0006869	lipid transport	2.728669e-9
GO:0072376	protein activation cascade	2.777856e-9
GO:0014057	positive regulation of acetylcholine secretion	2.885635e-9
GO:0008202	steroid metabolic process	3.130218e-9
GO:0030817	regulation of cAMP biosynthetic process	3.153836e-9
GO:0045761	regulation of adenylate cyclase activity	3.276336e-9
GO:0042060	wound healing	3.309803e-9
GO:0046903	secretion	3.463574e-9
GO:0006468	protein phosphorylation	3.995533e-9
GO:0055080	cation homeostasis	4.403811e-9
GO:0035815	positive regulation of renal sodium excretion	4.713133e-9
GO:0003008	system process	4.912746e-9
GO:0002429	immune response-activating cell surface receptor signaling pathway	4.996164e-9
GO:0032880	regulation of protein localization	5.620472e-9
GO:0019752	carboxylic acid metabolic process	5.719185e-9
GO:0051248	negative regulation of protein metabolic process	5.907749e-9
GO:0042180	cellular ketone metabolic process	6.481782e-9
GO:0001817	regulation of cytokine production	6.686179e-9
GO:0070201	regulation of establishment of protein localization	6.757145e-9
GO:0002768	immune response-regulating cell surface receptor signaling pathway	7.315546e-9
GO:0050852	T cell receptor signaling pathway	8.372658e-9
GO:0018958	phenol-containing compound metabolic process	8.726151e-9
GO:0072503	cellular divalent inorganic cation homeostasis	8.868608e-9
GO:0009063	cellular amino acid catabolic process	1.053873e-8
GO:0048522	positive regulation of cellular process	1.164867e-8
GO:0043412	macromolecule modification	1.295085e-8
GO:0050793	regulation of developmental process	1.383660e-8
GO:0006082	organic acid metabolic process	1.386143e-8
GO:0048143	astrocyte activation	1.437285e-8
GO:0010817	regulation of hormone levels	1.701961e-8
GO:0051349	positive regulation of lyase activity	1.715803e-8
GO:0006959	humoral immune response	1.744286e-8
GO:0034341	response to interferon-gamma	1.819496e-8
GO:0046395	carboxylic acid catabolic process	1.924995e-8
GO:0045088	regulation of innate immune response	2.018468e-8
GO:0045089	positive regulation of innate immune response	2.018784e-8
GO:0009266	response to temperature stimulus	2.086401e-8
GO:0042445	hormone metabolic process	2.179791e-8
GO:0044238	primary metabolic process	2.195061e-8
GO:0009310	amine catabolic process	2.356998e-8
GO:0035810	positive regulation of urine volume	2.465487e-8
GO:0009888	tissue development	2.718080e-8
GO:0042403	thyroid hormone metabolic process	2.767325e-8
GO:0031349	positive regulation of defense response	2.900735e-8
GO:0002221	pattern recognition receptor signaling pathway	3.133357e-8
GO:0002758	innate immune response-activating signal transduction	3.197503e-8
GO:0031281	positive regulation of cyclase activity	3.287563e-8
GO:0034762	regulation of transmembrane transport	3.521164e-8
GO:0048731	system development	3.641915e-8
GO:0043067	regulation of programmed cell death	3.964210e-8
GO:0006590	thyroid hormone generation	4.018244e-8
GO:0006520	cellular amino acid metabolic process	4.228015e-8
GO:0001933	negative regulation of protein phosphorylation	4.317327e-8
GO:0010941	regulation of cell death	4.722099e-8
GO:0042537	benzene-containing compound metabolic process	4.902037e-8
GO:0035093	spermatogenesis, exchange of chromosomal proteins	5.539507e-8
GO:0042127	regulation of cell proliferation	5.610094e-8
GO:0072507	divalent inorganic cation homeostasis	5.616640e-8
GO:0042981	regulation of apoptosis	5.806626e-8
GO:0002218	activation of innate immune response	6.487849e-8
GO:0014002	astrocyte development	6.491097e-8
GO:0050900	leukocyte migration	6.546443e-8
GO:0031099	regeneration	6.725635e-8
GO:0065009	regulation of molecular function	7.017907e-8
GO:0016310	phosphorylation	7.295923e-8
GO:0044255	cellular lipid metabolic process	7.661725e-8
GO:0051128	regulation of cellular component organization	7.800261e-8
GO:0006874	cellular calcium ion homeostasis	7.988578e-8
GO:0009605	response to external stimulus	9.558286e-8
GO:0006464	protein modification process	9.944012e-8
GO:0010876	lipid localization	1.023931e-7
GO:0009056	catabolic process	1.117176e-7
GO:0014056	regulation of acetylcholine secretion	1.152991e-7
GO:0010756	positive regulation of plasminogen activation	1.279324e-7
GO:0002694	regulation of leukocyte activation	1.312199e-7
GO:0006887	exocytosis	1.381461e-7
GO:0051222	positive regulation of protein transport	1.393755e-7
GO:0007190	activation of adenylate cyclase activity	1.439663e-7
GO:0050708	regulation of protein secretion	1.463885e-7
GO:0055074	calcium ion homeostasis	1.589393e-7
GO:0006956	complement activation	1.600182e-7
GO:0060341	regulation of cellular localization	1.869387e-7
GO:0006554	lysine catabolic process	1.874658e-7
GO:0045762	positive regulation of adenylate cyclase activity	1.940612e-7
GO:0006796	phosphate-containing compound metabolic process	1.951068e-7
GO:0050865	regulation of cell activation	2.112201e-7
GO:0050863	regulation of T cell activation	2.622199e-7
GO:0007599	hemostasis	2.774829e-7
GO:0007596	blood coagulation	2.888943e-7
GO:0050878	regulation of body fluid levels	3.014101e-7
GO:0071345	cellular response to cytokine stimulus	3.155759e-7
GO:0002526	acute inflammatory response	3.209521e-7
GO:0015705	iodide transport	3.332483e-7
GO:0048585	negative regulation of response to stimulus	3.428078e-7
GO:0071702	organic substance transport	3.450248e-7
GO:0002522	leukocyte migration involved in immune response	3.708543e-7
GO:0016064	immunoglobulin mediated immune response	3.768238e-7
GO:0009408	response to heat	4.161706e-7
GO:0002252	immune effector process	4.173310e-7
GO:0002885	positive regulation of hypersensitivity	4.328504e-7
GO:0031000	response to caffeine	4.362900e-7
GO:0071310	cellular response to organic substance	4.552118e-7
GO:0046486	glycerolipid metabolic process	4.747019e-7
GO:0008063	Toll signaling pathway	4.931343e-7
GO:0051249	regulation of lymphocyte activation	4.938948e-7
GO:0043068	positive regulation of programmed cell death	4.944732e-7
GO:0042098	T cell proliferation	5.012918e-7
GO:0050877	neurological system process	5.112845e-7
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	5.214508e-7
GO:0032680	regulation of tumor necrosis factor production	5.236146e-7
GO:0002883	regulation of hypersensitivity	5.390567e-7
GO:0006306	DNA methylation	5.600351e-7
GO:0050851	antigen receptor-mediated signaling pathway	5.714925e-7
GO:0050819	negative regulation of coagulation	6.149608e-7
GO:0044092	negative regulation of molecular function	6.379305e-7
GO:0009725	response to hormone stimulus	6.466096e-7
GO:0060249	anatomical structure homeostasis	6.800234e-7
GO:0001819	positive regulation of cytokine production	6.982185e-7
GO:0034446	substrate adhesion-dependent cell spreading	7.001229e-7
GO:0051384	response to glucocorticoid stimulus	7.105884e-7
GO:0051024	positive regulation of immunoglobulin secretion	7.256555e-7
GO:0010942	positive regulation of cell death	7.770064e-7
GO:0050867	positive regulation of cell activation	7.781548e-7
GO:0030168	platelet activation	7.995378e-7
GO:0044282	small molecule catabolic process	7.996877e-7
GO:0002443	leukocyte mediated immunity	8.088413e-7
GO:0019722	calcium-mediated signaling	8.193767e-7
GO:0051047	positive regulation of secretion	8.205838e-7
GO:0010743	regulation of macrophage derived foam cell differentiation	8.222888e-7
GO:0001963	synaptic transmission, dopaminergic	8.655034e-7
GO:0010874	regulation of cholesterol efflux	9.877070e-7
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1.012227e-6
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.021453e-6
GO:0002696	positive regulation of leukocyte activation	1.041865e-6
GO:0006570	tyrosine metabolic process	1.043428e-6
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	1.060892e-6
GO:0034381	plasma lipoprotein particle clearance	1.068800e-6
GO:0035809	regulation of urine volume	1.099558e-6
GO:0019226	transmission of nerve impulse	1.107327e-6
GO:0050870	positive regulation of T cell activation	1.146873e-6
GO:0006572	tyrosine catabolic process	1.166944e-6
GO:0044093	positive regulation of molecular function	1.170688e-6
GO:0032374	regulation of cholesterol transport	1.217971e-6
GO:0030595	leukocyte chemotaxis	1.241427e-6
GO:0010466	negative regulation of peptidase activity	1.281445e-6
GO:0009746	response to hexose stimulus	1.349092e-6
GO:0071841	cellular component organization or biogenesis at cellular level	1.371816e-6
GO:0043065	positive regulation of apoptosis	1.417375e-6
GO:0002224	toll-like receptor signaling pathway	1.421685e-6
GO:0052547	regulation of peptidase activity	1.572130e-6
GO:0034134	toll-like receptor 2 signaling pathway	1.575745e-6
GO:0034130	toll-like receptor 1 signaling pathway	1.575745e-6
GO:0007271	synaptic transmission, cholinergic	1.742841e-6
GO:0031647	regulation of protein stability	1.773721e-6
GO:0044062	regulation of excretion	1.794697e-6
GO:0009581	detection of external stimulus	1.794720e-6
GO:0016337	cell-cell adhesion	1.839322e-6
GO:0009749	response to glucose stimulus	1.901004e-6
GO:0042110	T cell activation	1.962282e-6
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2.009283e-6
GO:0034138	toll-like receptor 3 signaling pathway	2.087233e-6
GO:0051606	detection of stimulus	2.137474e-6
GO:0051649	establishment of localization in cell	2.270195e-6
GO:0032230	positive regulation of synaptic transmission, GABAergic	2.296440e-6
GO:0051241	negative regulation of multicellular organismal process	2.374879e-6
GO:0021544	subpallium development	2.421739e-6
GO:0006909	phagocytosis	2.449847e-6
GO:0007597	blood coagulation, intrinsic pathway	2.543972e-6
GO:0044248	cellular catabolic process	2.701476e-6
GO:0034142	toll-like receptor 4 signaling pathway	2.854894e-6
GO:0071842	cellular component organization at cellular level	2.928632e-6
GO:0010647	positive regulation of cell communication	3.011673e-6
GO:0006915	apoptosis	3.038000e-6
GO:0019724	B cell mediated immunity	3.108211e-6
GO:0006897	endocytosis	3.291777e-6
GO:0019932	second-messenger-mediated signaling	3.423147e-6
GO:0009968	negative regulation of signal transduction	3.466727e-6
GO:0051046	regulation of secretion	3.517482e-6
GO:0009719	response to endogenous stimulus	3.552953e-6
GO:0007525	somatic muscle development	3.607350e-6
GO:0097006	regulation of plasma lipoprotein particle levels	3.651311e-6
GO:2000026	regulation of multicellular organismal development	3.651656e-6
GO:0043114	regulation of vascular permeability	3.716322e-6
GO:0034284	response to monosaccharide stimulus	3.816313e-6
GO:0046634	regulation of alpha-beta T cell activation	4.062277e-6
GO:0007268	synaptic transmission	4.138329e-6
GO:0051251	positive regulation of lymphocyte activation	4.183119e-6
GO:0002756	MyD88-independent toll-like receptor signaling pathway	4.191991e-6
GO:0035813	regulation of renal sodium excretion	4.233370e-6
GO:0043116	negative regulation of vascular permeability	4.436703e-6
GO:0030277	maintenance of gastrointestinal epithelium	4.659937e-6
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	4.814930e-6
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	4.824325e-6
GO:0006958	complement activation, classical pathway	4.829669e-6
GO:0031100	organ regeneration	4.914399e-6
GO:0043086	negative regulation of catalytic activity	4.969342e-6
GO:0009744	response to sucrose stimulus	5.663613e-6
GO:0009156	ribonucleoside monophosphate biosynthetic process	5.789571e-6
GO:0021756	striatum development	5.866212e-6
GO:0010648	negative regulation of cell communication	5.895354e-6
GO:0044237	cellular metabolic process	5.950366e-6
GO:0012501	programmed cell death	6.196355e-6
GO:0001959	regulation of cytokine-mediated signaling pathway	6.220323e-6
GO:0060074	synapse maturation	6.367646e-6
GO:0009629	response to gravity	6.413427e-6
GO:0023057	negative regulation of signaling	6.464818e-6
GO:0051480	cytosolic calcium ion homeostasis	6.527864e-6
GO:0023056	positive regulation of signaling	6.956821e-6
GO:0000266	mitochondrial fission	7.014181e-6
GO:0051023	regulation of immunoglobulin secretion	7.228269e-6
GO:0018904	organic ether metabolic process	7.581682e-6
GO:0045343	regulation of MHC class I biosynthetic process	7.888102e-6
GO:0019439	aromatic compound catabolic process	8.107687e-6
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	8.117643e-6
GO:0045730	respiratory burst	8.149214e-6
GO:0006916	anti-apoptosis	8.301150e-6
GO:0032101	regulation of response to external stimulus	8.323983e-6
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	8.512761e-6
GO:0006914	autophagy	8.618801e-6
GO:0048660	regulation of smooth muscle cell proliferation	9.061908e-6
GO:0040011	locomotion	9.139109e-6
GO:0050821	protein stabilization	9.539709e-6
GO:0002455	humoral immune response mediated by circulating immunoglobulin	9.709054e-6
GO:0001973	adenosine receptor signaling pathway	9.968800e-6
GO:0009048	dosage compensation, by inactivation of X chromosome	1.007707e-5
GO:0051968	positive regulation of synaptic transmission, glutamatergic	1.037090e-5
GO:0031098	stress-activated protein kinase signaling cascade	1.080027e-5
GO:0045346	regulation of MHC class II biosynthetic process	1.097613e-5
GO:2000507	positive regulation of energy homeostasis	1.116104e-5
GO:2000253	positive regulation of feeding behavior	1.116104e-5
GO:0014074	response to purine-containing compound	1.128947e-5
GO:0050709	negative regulation of protein secretion	1.129994e-5
GO:0019221	cytokine-mediated signaling pathway	1.137173e-5
GO:0009582	detection of abiotic stimulus	1.238945e-5
GO:0060821	inactivation of X chromosome by DNA methylation	1.260089e-5
GO:0034764	positive regulation of transmembrane transport	1.283856e-5
GO:0015698	inorganic anion transport	1.309000e-5
GO:0060759	regulation of response to cytokine stimulus	1.319472e-5
GO:0002274	myeloid leukocyte activation	1.336084e-5
GO:0021782	glial cell development	1.346805e-5
GO:0007204	elevation of cytosolic calcium ion concentration	1.368322e-5
GO:0014049	positive regulation of glutamate secretion	1.371096e-5
GO:0051224	negative regulation of protein transport	1.379837e-5
GO:0071286	cellular response to magnesium ion	1.433193e-5
GO:0032370	positive regulation of lipid transport	1.446444e-5
GO:0035556	intracellular signal transduction	1.454350e-5
GO:0051403	stress-activated MAPK cascade	1.466209e-5
GO:0009112	nucleobase metabolic process	1.494079e-5
GO:0009068	aspartate family amino acid catabolic process	1.532223e-5
GO:0008610	lipid biosynthetic process	1.599336e-5
GO:0008037	cell recognition	1.609465e-5
GO:0033157	regulation of intracellular protein transport	1.628782e-5
GO:0035092	sperm chromatin condensation	1.631306e-5
GO:0019222	regulation of metabolic process	1.752462e-5
GO:0044419	interspecies interaction between organisms	1.779230e-5
GO:0006662	glycerol ether metabolic process	1.823455e-5
GO:0032870	cellular response to hormone stimulus	1.944328e-5
GO:0006953	acute-phase response	1.995242e-5
GO:0046483	heterocycle metabolic process	2.001561e-5
GO:0006576	cellular biogenic amine metabolic process	2.013546e-5
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	2.052789e-5
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2.065771e-5
GO:0042119	neutrophil activation	2.102405e-5
GO:0009066	aspartate family amino acid metabolic process	2.151760e-5
GO:0032534	regulation of microvillus assembly	2.197549e-5
GO:0032735	positive regulation of interleukin-12 production	2.225774e-5
GO:0070101	positive regulation of chemokine-mediated signaling pathway	2.233255e-5
GO:0032368	regulation of lipid transport	2.243857e-5
GO:0042176	regulation of protein catabolic process	2.265833e-5
GO:0010669	epithelial structure maintenance	2.328563e-5
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.355074e-5
GO:0045834	positive regulation of lipid metabolic process	2.381501e-5
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	2.606416e-5
GO:0010883	regulation of lipid storage	2.606416e-5
GO:0006559	L-phenylalanine catabolic process	2.610034e-5
GO:0070099	regulation of chemokine-mediated signaling pathway	2.637168e-5
GO:0032269	negative regulation of cellular protein metabolic process	2.656188e-5
GO:0043269	regulation of ion transport	2.801119e-5
GO:0046600	negative regulation of centriole replication	2.996577e-5
GO:0050707	regulation of cytokine secretion	3.000094e-5
GO:0045348	positive regulation of MHC class II biosynthetic process	3.022840e-5
GO:0001956	positive regulation of neurotransmitter secretion	3.049763e-5
GO:0010875	positive regulation of cholesterol efflux	3.163581e-5
GO:0042325	regulation of phosphorylation	3.260405e-5
GO:0008211	glucocorticoid metabolic process	3.500568e-5
GO:0001812	positive regulation of type I hypersensitivity	3.501294e-5
GO:0035058	nonmotile primary cilium assembly	3.509418e-5
GO:0006575	cellular modified amino acid metabolic process	3.638453e-5
GO:0007194	negative regulation of adenylate cyclase activity	3.645471e-5
GO:0002407	dendritic cell chemotaxis	3.726804e-5
GO:0006664	glycolipid metabolic process	3.786036e-5
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.836709e-5
GO:0006639	acylglycerol metabolic process	3.843615e-5
GO:0032570	response to progesterone stimulus	3.857526e-5
GO:0034330	cell junction organization	4.025442e-5
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	4.055448e-5
GO:0048871	multicellular organismal homeostasis	4.061438e-5
GO:0046822	regulation of nucleocytoplasmic transport	4.069660e-5
GO:0072593	reactive oxygen species metabolic process	4.097816e-5
GO:0007631	feeding behavior	4.101734e-5
GO:0007050	cell cycle arrest	4.101937e-5
GO:0020027	hemoglobin metabolic process	4.127564e-5
GO:0035295	tube development	4.155432e-5
GO:0032966	negative regulation of collagen biosynthetic process	4.166859e-5
GO:0032386	regulation of intracellular transport	4.231909e-5
GO:0032655	regulation of interleukin-12 production	4.338548e-5
GO:0045345	positive regulation of MHC class I biosynthetic process	4.360647e-5
GO:0044267	cellular protein metabolic process	4.480446e-5
GO:0052548	regulation of endopeptidase activity	4.513774e-5
GO:0006641	triglyceride metabolic process	4.557912e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	4.654268e-5
GO:0048468	cell development	4.673298e-5
GO:0043558	regulation of translational initiation in response to stress	4.675855e-5
GO:0043304	regulation of mast cell degranulation	4.819031e-5
GO:0030832	regulation of actin filament length	4.849786e-5
GO:0009967	positive regulation of signal transduction	4.872330e-5
GO:0031946	regulation of glucocorticoid biosynthetic process	5.050812e-5
GO:0072358	cardiovascular system development	5.111260e-5
GO:0031282	regulation of guanylate cyclase activity	5.207708e-5
GO:0051094	positive regulation of developmental process	5.369675e-5
GO:0042541	hemoglobin biosynthetic process	5.393824e-5
GO:0010869	regulation of receptor biosynthetic process	5.482379e-5
GO:0006144	purine base metabolic process	5.489958e-5
GO:0042306	regulation of protein import into nucleus	5.519688e-5
GO:0050727	regulation of inflammatory response	5.528867e-5
GO:0046548	retinal rod cell development	5.565221e-5
GO:0010038	response to metal ion	5.600481e-5
GO:0051588	regulation of neurotransmitter transport	5.626758e-5
GO:0009615	response to virus	5.765241e-5
GO:0009100	glycoprotein metabolic process	5.817515e-5
GO:0035413	positive regulation of catenin import into nucleus	5.822834e-5
GO:0046700	heterocycle catabolic process	5.860549e-5
GO:0016098	monoterpenoid metabolic process	6.320054e-5
GO:0032736	positive regulation of interleukin-13 production	6.337362e-5
GO:0051346	negative regulation of hydrolase activity	6.388095e-5
GO:0045444	fat cell differentiation	6.432698e-5
GO:0006508	proteolysis	6.482817e-5
GO:0009161	ribonucleoside monophosphate metabolic process	6.505495e-5
GO:0040012	regulation of locomotion	6.508959e-5
GO:0070723	response to cholesterol	6.591438e-5
GO:0015671	oxygen transport	6.596227e-5
GO:0071241	cellular response to inorganic substance	6.620765e-5
GO:2000534	positive regulation of renal albumin absorption	7.036017e-5
GO:0070994	detection of oxidative stress	7.036017e-5
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	7.036017e-5
GO:2000461	negative regulation of eukaryotic cell surface binding	7.036017e-5
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	7.036017e-5
GO:0045767	regulation of anti-apoptosis	7.058333e-5
GO:0032720	negative regulation of tumor necrosis factor production	7.070273e-5
GO:0034329	cell junction assembly	7.306655e-5
GO:0032530	regulation of microvillus organization	7.502400e-5
GO:0032376	positive regulation of cholesterol transport	7.530005e-5
GO:0033006	regulation of mast cell activation involved in immune response	7.583262e-5
GO:0046824	positive regulation of nucleocytoplasmic transport	7.659170e-5
GO:0042742	defense response to bacterium	7.693863e-5
GO:0019216	regulation of lipid metabolic process	8.066820e-5
GO:0002430	complement receptor mediated signaling pathway	8.067580e-5
GO:0050710	negative regulation of cytokine secretion	8.575367e-5
GO:0001960	negative regulation of cytokine-mediated signaling pathway	9.042270e-5
GO:0030325	adrenal gland development	9.074967e-5
GO:0003417	growth plate cartilage development	9.112014e-5
GO:0001894	tissue homeostasis	9.193011e-5
GO:0031348	negative regulation of defense response	9.264400e-5
GO:0032494	response to peptidoglycan	9.431068e-5
GO:0090208	positive regulation of triglyceride metabolic process	9.481294e-5
GO:0007626	locomotory behavior	9.555473e-5
GO:0043402	glucocorticoid mediated signaling pathway	9.647668e-5
GO:0030522	intracellular receptor mediated signaling pathway	9.725327e-5
GO:0032350	regulation of hormone metabolic process	9.878659e-5
GO:0035588	G-protein coupled purinergic receptor signaling pathway	9.884582e-5
GO:0030154	cell differentiation	9.922041e-5
GO:0051350	negative regulation of lyase activity	1.027154e-4
GO:0009249	protein lipoylation	1.036476e-4
GO:0006638	neutral lipid metabolic process	1.056478e-4
GO:0046928	regulation of neurotransmitter secretion	1.068407e-4
GO:0002355	detection of tumor cell	1.079853e-4
GO:0051412	response to corticosterone stimulus	1.098945e-4
GO:0050818	regulation of coagulation	1.102360e-4
GO:0048732	gland development	1.115238e-4
GO:0006527	arginine catabolic process	1.127801e-4
GO:0048305	immunoglobulin secretion	1.138495e-4
GO:0006811	ion transport	1.153086e-4
GO:0090023	positive regulation of neutrophil chemotaxis	1.154682e-4
GO:0042990	regulation of transcription factor import into nucleus	1.173560e-4
GO:0022607	cellular component assembly	1.186639e-4
GO:0019220	regulation of phosphate metabolic process	1.194521e-4
GO:0042554	superoxide anion generation	1.198087e-4
GO:0032677	regulation of interleukin-8 production	1.198665e-4
GO:0007040	lysosome organization	1.206007e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0009611	response to wounding	2.196142e-17
GO:0050896	response to stimulus	9.366431e-16
GO:0050865	regulation of cell activation	2.501208e-14
GO:0042060	wound healing	2.696133e-14
GO:0002694	regulation of leukocyte activation	7.498869e-14
GO:0006950	response to stress	2.699272e-12
GO:0006812	cation transport	3.464030e-12
GO:0051249	regulation of lymphocyte activation	2.105131e-11
GO:0006810	transport	4.659632e-11
GO:0051234	establishment of localization	5.035210e-11
GO:0032879	regulation of localization	1.150474e-10
GO:0055114	oxidation-reduction process	1.172957e-10
GO:0006811	ion transport	2.487561e-10
GO:0010038	response to metal ion	2.666420e-10
GO:0051179	localization	6.746629e-10
GO:0050864	regulation of B cell activation	1.118430e-9
GO:0006952	defense response	2.528732e-9
GO:0002682	regulation of immune system process	2.561381e-9
GO:0019752	carboxylic acid metabolic process	3.355479e-9
GO:0070663	regulation of leukocyte proliferation	5.322435e-9
GO:0050670	regulation of lymphocyte proliferation	5.954310e-9
GO:0022610	biological adhesion	5.984360e-9
GO:0030001	metal ion transport	7.576495e-9
GO:0042180	cellular ketone metabolic process	7.825023e-9
GO:0007186	G-protein coupled receptor protein signaling pathway	8.626207e-9
GO:0032944	regulation of mononuclear cell proliferation	8.825842e-9
GO:0006082	organic acid metabolic process	9.670912e-9
GO:0010269	response to selenium ion	1.101737e-8
GO:0044281	small molecule metabolic process	1.249587e-8
GO:0006629	lipid metabolic process	1.258921e-8
GO:0006954	inflammatory response	1.277281e-8
GO:0007155	cell adhesion	1.348423e-8
GO:0030888	regulation of B cell proliferation	1.697683e-8
GO:0051250	negative regulation of lymphocyte activation	2.439963e-8
GO:0051716	cellular response to stimulus	3.204572e-8
GO:0048583	regulation of response to stimulus	3.755783e-8
GO:0071219	cellular response to molecule of bacterial origin	3.771987e-8
GO:0050863	regulation of T cell activation	3.822033e-8
GO:0050866	negative regulation of cell activation	4.027636e-8
GO:0071222	cellular response to lipopolysaccharide	5.268886e-8
GO:0008610	lipid biosynthetic process	5.877433e-8
GO:0043949	regulation of cAMP-mediated signaling	6.181847e-8
GO:0002695	negative regulation of leukocyte activation	7.480688e-8
GO:0042221	response to chemical stimulus	7.573355e-8
GO:0002376	immune system process	7.691285e-8
GO:0010715	regulation of extracellular matrix disassembly	8.897203e-8
GO:0051049	regulation of transport	1.077384e-7
GO:0044255	cellular lipid metabolic process	1.226169e-7
GO:0006749	glutathione metabolic process	1.269558e-7
GO:0055085	transmembrane transport	1.285837e-7
GO:0018879	biphenyl metabolic process	1.822613e-7
GO:0044062	regulation of excretion	2.269163e-7
GO:0010035	response to inorganic substance	2.436985e-7
GO:0006518	peptide metabolic process	3.045198e-7
GO:0019285	glycine betaine biosynthetic process from choline	3.218360e-7
GO:0002252	immune effector process	3.271168e-7
GO:0009098	leucine biosynthetic process	4.045631e-7
GO:0006550	isoleucine catabolic process	4.045631e-7
GO:0006578	betaine biosynthetic process	4.615884e-7
GO:0030890	positive regulation of B cell proliferation	4.682654e-7
GO:0051707	response to other organism	4.712652e-7
GO:0001818	negative regulation of cytokine production	4.718560e-7
GO:0007596	blood coagulation	4.724615e-7
GO:0002238	response to molecule of fungal origin	5.676143e-7
GO:0007599	hemostasis	5.890056e-7
GO:2000021	regulation of ion homeostasis	6.100872e-7
GO:0007166	cell surface receptor linked signaling pathway	9.498253e-7
GO:0065008	regulation of biological quality	1.011724e-6
GO:0050868	negative regulation of T cell activation	1.114473e-6
GO:0044283	small molecule biosynthetic process	1.305330e-6
GO:0050776	regulation of immune response	1.356534e-6
GO:0050871	positive regulation of B cell activation	1.392426e-6
GO:0009115	xanthine catabolic process	1.616026e-6
GO:0002683	negative regulation of immune system process	1.692274e-6
GO:0034765	regulation of ion transmembrane transport	1.725600e-6
GO:0051241	negative regulation of multicellular organismal process	1.815601e-6
GO:0045348	positive regulation of MHC class II biosynthetic process	2.114516e-6
GO:0002684	positive regulation of immune system process	2.134306e-6
GO:0071216	cellular response to biotic stimulus	2.602692e-6
GO:0060055	angiogenesis involved in wound healing	2.615568e-6
GO:0002819	regulation of adaptive immune response	2.819943e-6
GO:0009607	response to biotic stimulus	3.184075e-6
GO:0002637	regulation of immunoglobulin production	3.344168e-6
GO:0042246	tissue regeneration	3.602379e-6
GO:0051704	multi-organism process	3.962251e-6
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	4.206083e-6
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.795698e-6
GO:0006968	cellular defense response	4.938574e-6
GO:0042100	B cell proliferation	5.139402e-6
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.236270e-6
GO:0018963	phthalate metabolic process	5.403482e-6
GO:0090280	positive regulation of calcium ion import	5.654077e-6
GO:0032733	positive regulation of interleukin-10 production	5.864366e-6
GO:0051023	regulation of immunoglobulin secretion	5.968041e-6
GO:0002820	negative regulation of adaptive immune response	6.110252e-6
GO:0023052	signaling	6.218861e-6
GO:0043951	negative regulation of cAMP-mediated signaling	6.244855e-6
GO:0006694	steroid biosynthetic process	6.260998e-6
GO:0019376	galactolipid catabolic process	7.492377e-6
GO:0006702	androgen biosynthetic process	7.952643e-6
GO:0060249	anatomical structure homeostasis	1.034616e-5
GO:0002921	negative regulation of humoral immune response	1.083723e-5
GO:0070664	negative regulation of leukocyte proliferation	1.122505e-5
GO:0051046	regulation of secretion	1.131399e-5
GO:0002700	regulation of production of molecular mediator of immune response	1.201653e-5
GO:0050672	negative regulation of lymphocyte proliferation	1.324779e-5
GO:0061088	regulation of sequestering of zinc ion	1.363315e-5
GO:0035444	nickel ion transmembrane transport	1.363315e-5
GO:0019932	second-messenger-mediated signaling	1.412097e-5
GO:0051918	negative regulation of fibrinolysis	1.426440e-5
GO:0008284	positive regulation of cell proliferation	1.429037e-5
GO:0042953	lipoprotein transport	1.499178e-5
GO:0010312	detoxification of zinc ion	1.499951e-5
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.543820e-5
GO:2000353	positive regulation of endothelial cell apoptosis	1.550465e-5
GO:0023051	regulation of signaling	1.604734e-5
GO:0048584	positive regulation of response to stimulus	1.751203e-5
GO:0002697	regulation of immune effector process	1.774635e-5
GO:0006551	leucine metabolic process	1.832230e-5
GO:0060206	estrous cycle phase	1.835708e-5
GO:0009620	response to fungus	1.866179e-5
GO:0007165	signal transduction	1.872596e-5
GO:0002443	leukocyte mediated immunity	2.074133e-5
GO:0034220	ion transmembrane transport	2.188463e-5
GO:0051054	positive regulation of DNA metabolic process	2.377176e-5
GO:0001817	regulation of cytokine production	2.387817e-5
GO:0045823	positive regulation of heart contraction	2.440622e-5
GO:0015920	lipopolysaccharide transport	2.809887e-5
GO:0018894	dibenzo-p-dioxin metabolic process	2.898258e-5
GO:0018026	peptidyl-lysine monomethylation	2.898258e-5
GO:0019374	galactolipid metabolic process	2.988619e-5
GO:0046113	nucleobase catabolic process	3.047615e-5
GO:0002889	regulation of immunoglobulin mediated immune response	3.190947e-5
GO:0006955	immune response	3.237994e-5
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.381842e-5
GO:0046485	ether lipid metabolic process	3.384811e-5
GO:0090066	regulation of anatomical structure size	3.437329e-5
GO:0006829	zinc ion transport	3.508152e-5
GO:0008202	steroid metabolic process	3.663737e-5
GO:0060658	nipple morphogenesis	3.845137e-5
GO:0035813	regulation of renal sodium excretion	3.893025e-5
GO:0050778	positive regulation of immune response	3.959364e-5
GO:0015734	taurine transport	4.027112e-5
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	4.027112e-5
GO:0055093	response to hyperoxia	4.168043e-5
GO:0009617	response to bacterium	4.313119e-5
GO:0048302	regulation of isotype switching to IgG isotypes	4.474539e-5
GO:0002449	lymphocyte mediated immunity	4.478371e-5
GO:0071732	cellular response to nitric oxide	4.586088e-5
GO:0002920	regulation of humoral immune response	4.906247e-5
GO:0032714	negative regulation of interleukin-5 production	5.071565e-5
GO:0048305	immunoglobulin secretion	5.071565e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	5.159733e-5
GO:0048625	myoblast cell fate commitment	5.578206e-5
GO:0032653	regulation of interleukin-10 production	5.613934e-5
GO:0046110	xanthine metabolic process	5.810865e-5
GO:0030194	positive regulation of blood coagulation	6.008063e-5
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	6.111042e-5
GO:0045911	positive regulation of DNA recombination	6.131037e-5
GO:0035814	negative regulation of renal sodium excretion	6.227035e-5
GO:0006575	cellular modified amino acid metabolic process	6.322569e-5
GO:0042127	regulation of cell proliferation	6.415421e-5
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	6.528428e-5
GO:0031340	positive regulation of vesicle fusion	6.529915e-5
GO:0007567	parturition	6.538063e-5
GO:0051856	adhesion to symbiont	6.585689e-5
GO:0009966	regulation of signal transduction	6.731648e-5
GO:0009308	amine metabolic process	6.807006e-5
GO:0015684	ferrous iron transport	6.914601e-5
GO:0006012	galactose metabolic process	7.067752e-5
GO:0090279	regulation of calcium ion import	7.410290e-5
GO:0046486	glycerolipid metabolic process	7.461613e-5
GO:0048870	cell motility	7.472165e-5
GO:0042448	progesterone metabolic process	7.934755e-5
GO:0010033	response to organic substance	7.994425e-5
GO:0007154	cell communication	8.670430e-5
GO:0010894	negative regulation of steroid biosynthetic process	8.762993e-5
GO:0002200	somatic diversification of immune receptors	9.278704e-5
GO:0014002	astrocyte development	9.390451e-5
GO:0071560	cellular response to transforming growth factor beta stimulus	9.740309e-5
GO:0032787	monocarboxylic acid metabolic process	9.748738e-5
GO:0016074	snoRNA metabolic process	9.864797e-5
GO:0071577	zinc ion transmembrane transport	9.914100e-5
GO:0015672	monovalent inorganic cation transport	1.017762e-4
GO:0045576	mast cell activation	1.018333e-4
GO:0002706	regulation of lymphocyte mediated immunity	1.020703e-4
GO:0035458	cellular response to interferon-beta	1.093115e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.105613e-4
GO:0006688	glycosphingolipid biosynthetic process	1.133228e-4
GO:0035556	intracellular signal transduction	1.170369e-4
GO:0001775	cell activation	1.192821e-4
GO:0051917	regulation of fibrinolysis	1.221328e-4
GO:0032713	negative regulation of interleukin-4 production	1.221328e-4
GO:0070627	ferrous iron import	1.251527e-4
GO:0015692	lead ion transport	1.251527e-4
GO:0015676	vanadium ion transport	1.251527e-4
GO:0006520	cellular amino acid metabolic process	1.272428e-4
GO:0060575	intestinal epithelial cell differentiation	1.303294e-4
GO:0002237	response to molecule of bacterial origin	1.303599e-4
GO:0061303	cornea development in camera-type eye	1.326525e-4
GO:0045321	leukocyte activation	1.329503e-4
GO:0032101	regulation of response to external stimulus	1.341647e-4
GO:0002696	positive regulation of leukocyte activation	1.380971e-4
GO:0044092	negative regulation of molecular function	1.416837e-4
GO:0071423	malate transmembrane transport	1.459965e-4
GO:0015709	thiosulfate transport	1.459965e-4
GO:0034766	negative regulation of ion transmembrane transport	1.478933e-4
GO:0046640	regulation of alpha-beta T cell proliferation	1.548936e-4
GO:0070838	divalent metal ion transport	1.584450e-4
GO:2000741	positive regulation of mesenchymal stem cell differentiation	1.587435e-4
GO:0032696	negative regulation of interleukin-13 production	1.607348e-4
GO:0051043	regulation of membrane protein ectodomain proteolysis	1.670007e-4
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	1.670007e-4
GO:0045346	regulation of MHC class II biosynthetic process	1.707906e-4
GO:0046394	carboxylic acid biosynthetic process	1.740436e-4
GO:0051240	positive regulation of multicellular organismal process	1.750642e-4
GO:0007229	integrin-mediated signaling pathway	1.764160e-4
GO:0072511	divalent inorganic cation transport	1.785254e-4
GO:0050867	positive regulation of cell activation	1.831414e-4
GO:0006833	water transport	1.839128e-4
GO:0009247	glycolipid biosynthetic process	1.933091e-4
GO:0002709	regulation of T cell mediated immunity	2.111912e-4
GO:0050928	negative regulation of positive chemotaxis	2.141855e-4
GO:0051256	spindle midzone assembly involved in mitosis	2.141855e-4
GO:0032782	bile acid secretion	2.141855e-4
GO:0006844	acyl carnitine transport	2.141855e-4
GO:0003096	renal sodium ion transport	2.141855e-4
GO:0010466	negative regulation of peptidase activity	2.239406e-4
GO:0010646	regulation of cell communication	2.286118e-4
GO:0048103	somatic stem cell division	2.309149e-4
GO:0042129	regulation of T cell proliferation	2.330829e-4
GO:0032496	response to lipopolysaccharide	2.337029e-4
GO:0009408	response to heat	2.399223e-4
GO:0042044	fluid transport	2.430757e-4
GO:0010716	negative regulation of extracellular matrix disassembly	2.497327e-4
GO:0007268	synaptic transmission	2.522606e-4
GO:0071260	cellular response to mechanical stimulus	2.559887e-4
GO:0051024	positive regulation of immunoglobulin secretion	2.592020e-4
GO:0035330	regulation of hippo signaling cascade	2.610356e-4
GO:0045766	positive regulation of angiogenesis	2.743329e-4
GO:0002366	leukocyte activation involved in immune response	2.743329e-4
GO:0051607	defense response to virus	2.747674e-4
GO:0031572	G2/M transition DNA damage checkpoint	2.852118e-4
GO:0070665	positive regulation of leukocyte proliferation	2.883858e-4
GO:0034605	cellular response to heat	2.886283e-4
GO:0050671	positive regulation of lymphocyte proliferation	2.900399e-4
GO:0015722	canalicular bile acid transport	2.924392e-4
GO:0009187	cyclic nucleotide metabolic process	2.985141e-4
GO:0006836	neurotransmitter transport	3.005677e-4
GO:0048710	regulation of astrocyte differentiation	3.106131e-4
GO:0033574	response to testosterone stimulus	3.249992e-4
GO:0042267	natural killer cell mediated cytotoxicity	3.274604e-4
GO:0043687	post-translational protein modification	3.274604e-4
GO:0046651	lymphocyte proliferation	3.348662e-4
GO:0051592	response to calcium ion	3.381911e-4
GO:0031576	G2/M transition checkpoint	3.521088e-4
GO:0043269	regulation of ion transport	3.547622e-4
GO:0035610	protein side chain deglutamylation	3.551944e-4
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	3.551944e-4
GO:0035609	C-terminal protein deglutamylation	3.551944e-4
GO:0020028	hemoglobin import	3.551944e-4
GO:0045445	myoblast differentiation	3.658475e-4
GO:0050878	regulation of body fluid levels	3.737229e-4
GO:0032074	negative regulation of nuclease activity	3.795043e-4
GO:0006435	threonyl-tRNA aminoacylation	3.795043e-4
GO:0019226	transmission of nerve impulse	3.795394e-4
GO:0032946	positive regulation of mononuclear cell proliferation	3.832234e-4
GO:0071421	manganese ion transmembrane transport	3.885772e-4
GO:0006145	purine base catabolic process	3.885772e-4
GO:0045073	regulation of chemokine biosynthetic process	3.901297e-4
GO:0032844	regulation of homeostatic process	4.023739e-4
GO:0045765	regulation of angiogenesis	4.034711e-4
GO:0040017	positive regulation of locomotion	4.039703e-4
GO:0042167	heme catabolic process	4.048686e-4
GO:0008203	cholesterol metabolic process	4.061939e-4
GO:0002520	immune system development	4.148470e-4
GO:0045830	positive regulation of isotype switching	4.189629e-4
GO:0010648	negative regulation of cell communication	4.210285e-4
GO:0032656	regulation of interleukin-13 production	4.315423e-4
GO:0071559	response to transforming growth factor beta stimulus	4.316121e-4
GO:0034599	cellular response to oxidative stress	4.339405e-4
GO:0022408	negative regulation of cell-cell adhesion	4.417937e-4
GO:0022407	regulation of cell-cell adhesion	4.435305e-4
GO:0050678	regulation of epithelial cell proliferation	4.492560e-4
GO:0046903	secretion	4.580930e-4
GO:0050855	regulation of B cell receptor signaling pathway	4.601729e-4
GO:0042159	lipoprotein catabolic process	4.601729e-4
GO:0042744	hydrogen peroxide catabolic process	4.647034e-4
GO:0051272	positive regulation of cellular component movement	4.680078e-4
GO:0045191	regulation of isotype switching	4.686892e-4
GO:0051712	positive regulation of killing of cells of other organism	4.759786e-4
GO:0035644	phosphoanandamide dephosphorylation	4.759786e-4
GO:0043392	negative regulation of DNA binding	4.791156e-4
GO:0030335	positive regulation of cell migration	4.877044e-4
GO:2000739	regulation of mesenchymal stem cell differentiation	4.958627e-4
GO:0014070	response to organic cyclic compound	4.970539e-4
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	5.019900e-4
GO:0046185	aldehyde catabolic process	5.019900e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	5.070021e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	5.137294e-4
GO:0015893	drug transport	5.138023e-4
GO:0050869	negative regulation of B cell activation	5.143918e-4
GO:0005513	detection of calcium ion	5.250041e-4
GO:0014823	response to activity	5.266366e-4
GO:0042743	hydrogen peroxide metabolic process	5.294174e-4
GO:0006695	cholesterol biosynthetic process	5.328595e-4
GO:0071702	organic substance transport	5.354270e-4
GO:0030879	mammary gland development	5.376954e-4
GO:0034767	positive regulation of ion transmembrane transport	5.422904e-4
GO:0007549	dosage compensation	5.427927e-4
GO:0050880	regulation of blood vessel size	5.446349e-4
GO:0009593	detection of chemical stimulus	5.456715e-4
GO:0046578	regulation of Ras protein signal transduction	5.469405e-4
GO:0033490	cholesterol biosynthetic process via lathosterol	5.719891e-4
GO:0050851	antigen receptor-mediated signaling pathway	5.804169e-4
GO:0002703	regulation of leukocyte mediated immunity	5.812392e-4
GO:0032490	detection of molecule of bacterial origin	5.826634e-4
GO:0043303	mast cell degranulation	5.888695e-4
GO:0035150	regulation of tube size	5.895279e-4
GO:0023057	negative regulation of signaling	5.950276e-4
GO:0044264	cellular polysaccharide metabolic process	5.997339e-4
GO:0032703	negative regulation of interleukin-2 production	6.021129e-4
GO:0048016	inositol phosphate-mediated signaling	6.047312e-4
GO:0032673	regulation of interleukin-4 production	6.102606e-4
GO:0010460	positive regulation of heart rate	6.150143e-4
GO:0043558	regulation of translational initiation in response to stress	6.153676e-4
GO:0002072	optic cup morphogenesis involved in camera-type eye development	6.181468e-4
GO:0006957	complement activation, alternative pathway	6.189527e-4
GO:0030814	regulation of cAMP metabolic process	6.254832e-4
GO:0051056	regulation of small GTPase mediated signal transduction	6.259318e-4
GO:0016064	immunoglobulin mediated immune response	6.577529e-4
GO:0070301	cellular response to hydrogen peroxide	6.637201e-4
GO:0002253	activation of immune response	6.650822e-4
GO:0045821	positive regulation of glycolysis	6.684967e-4
GO:0072282	metanephric nephron tubule morphogenesis	6.719303e-4
GO:0009612	response to mechanical stimulus	6.733558e-4
GO:0071731	response to nitric oxide	6.757451e-4
GO:0031099	regeneration	6.865523e-4
GO:0042063	gliogenesis	6.873523e-4
GO:0044106	cellular amine metabolic process	6.882689e-4
GO:0032908	regulation of transforming growth factor beta1 production	6.903400e-4
GO:2001020	regulation of response to DNA damage stimulus	7.018118e-4
GO:0016477	cell migration	7.038611e-4
GO:0001916	positive regulation of T cell mediated cytotoxicity	7.053276e-4
GO:0051098	regulation of binding	7.318306e-4
GO:0002275	myeloid cell activation involved in immune response	7.364620e-4
GO:0001909	leukocyte mediated cytotoxicity	7.407936e-4
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	7.475024e-4
GO:0019240	citrulline biosynthetic process	7.475024e-4
GO:0017121	phospholipid scrambling	7.475024e-4
GO:0019724	B cell mediated immunity	7.649387e-4
GO:0048712	negative regulation of astrocyte differentiation	7.772652e-4
GO:0009749	response to glucose stimulus	7.871147e-4
GO:0070574	cadmium ion transmembrane transport	7.895106e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	7.905941e-4
GO:0043403	skeletal muscle tissue regeneration	7.917703e-4
GO:0042130	negative regulation of T cell proliferation	7.994149e-4
GO:0002377	immunoglobulin production	8.012712e-4
GO:0030817	regulation of cAMP biosynthetic process	8.031743e-4
GO:0019585	glucuronate metabolic process	8.034236e-4
GO:0010885	regulation of cholesterol storage	8.059862e-4
GO:0006233	dTDP biosynthetic process	8.117175e-4
GO:0051251	positive regulation of lymphocyte activation	8.194137e-4
GO:0033085	negative regulation of T cell differentiation in thymus	8.286784e-4
GO:0001894	tissue homeostasis	8.370619e-4
GO:0009410	response to xenobiotic stimulus	8.405057e-4
GO:2000377	regulation of reactive oxygen species metabolic process	8.504575e-4
GO:2000147	positive regulation of cell motility	8.534643e-4
GO:0072593	reactive oxygen species metabolic process	8.537371e-4
GO:2000736	regulation of stem cell differentiation	8.610963e-4
GO:0006406	mRNA export from nucleus	8.752110e-4
GO:0032098	regulation of appetite	8.831128e-4
GO:0034284	response to monosaccharide stimulus	8.848041e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	8.872130e-4
GO:0043299	leukocyte degranulation	8.915721e-4
GO:0051239	regulation of multicellular organismal process	8.932434e-4
GO:0015855	pyrimidine base transport	8.944209e-4
GO:0060157	urinary bladder development	9.020444e-4
GO:0032943	mononuclear cell proliferation	9.074030e-4
GO:0009636	response to toxin	9.174328e-4
GO:0000012	single strand break repair	9.234642e-4
GO:0050854	regulation of antigen receptor-mediated signaling pathway	9.252291e-4
GO:0032461	positive regulation of protein oligomerization	9.532581e-4
GO:2000505	regulation of energy homeostasis	9.595744e-4
GO:0015697	quaternary ammonium group transport	9.611264e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	9.667618e-4
GO:0006953	acute-phase response	9.678351e-4
GO:0042107	cytokine metabolic process	9.685018e-4
GO:0045087	innate immune response	9.724309e-4
GO:0034762	regulation of transmembrane transport	9.774838e-4
GO:0006405	RNA export from nucleus	9.904584e-4
GO:0045602	negative regulation of endothelial cell differentiation	1.009128e-3
GO:0065007	biological regulation	1.017248e-3
GO:0050852	T cell receptor signaling pathway	1.021836e-3
GO:0044262	cellular carbohydrate metabolic process	1.057812e-3
GO:0014074	response to purine-containing compound	1.063925e-3
GO:0051615	histamine uptake	1.076904e-3
GO:0043950	positive regulation of cAMP-mediated signaling	1.076904e-3
GO:0006633	fatty acid biosynthetic process	1.078656e-3
GO:0060586	multicellular organismal iron ion homeostasis	1.092470e-3
GO:0021589	cerebellum structural organization	1.092470e-3
GO:0050820	positive regulation of coagulation	1.102227e-3
GO:0046483	heterocycle metabolic process	1.117542e-3
GO:0090045	positive regulation of deacetylase activity	1.118562e-3
GO:0006577	betaine metabolic process	1.136850e-3
GO:0007521	muscle cell fate determination	1.161348e-3
GO:0035455	response to interferon-alpha	1.162894e-3
GO:0045777	positive regulation of blood pressure	1.182973e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	1.188393e-3
GO:0010001	glial cell differentiation	1.194540e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	1.201105e-3
GO:0051101	regulation of DNA binding	1.217812e-3
GO:0051593	response to folic acid	1.258929e-3
GO:0002711	positive regulation of T cell mediated immunity	1.259963e-3
GO:0002250	adaptive immune response	1.265726e-3
GO:0071345	cellular response to cytokine stimulus	1.272760e-3
GO:0008653	lipopolysaccharide metabolic process	1.274944e-3
GO:0009746	response to hexose stimulus	1.308228e-3
GO:0030799	regulation of cyclic nucleotide metabolic process	1.326893e-3
GO:0051099	positive regulation of binding	1.361629e-3
GO:0005975	carbohydrate metabolic process	1.446780e-3
GO:0030097	hemopoiesis	1.449340e-3
GO:0030802	regulation of cyclic nucleotide biosynthetic process	1.451245e-3
GO:0045079	negative regulation of chemokine biosynthetic process	1.473515e-3
GO:0031343	positive regulation of cell killing	1.475256e-3
GO:0033003	regulation of mast cell activation	1.486078e-3
GO:0003013	circulatory system process	1.490008e-3
GO:0046548	retinal rod cell development	1.492646e-3
GO:0050872	white fat cell differentiation	1.505984e-3
GO:0006104	succinyl-CoA metabolic process	1.535554e-3
GO:0060265	positive regulation of respiratory burst involved in inflammatory response	1.535554e-3
GO:0002232	leukocyte chemotaxis involved in inflammatory response	1.535554e-3
GO:0001781	neutrophil apoptosis	1.535554e-3
GO:0015837	amine transport	1.541840e-3
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.550073e-3
GO:0050920	regulation of chemotaxis	1.570407e-3
GO:0019233	sensory perception of pain	1.574227e-3
GO:0032940	secretion by cell	1.585161e-3
GO:0009306	protein secretion	1.588129e-3
GO:0050900	leukocyte migration	1.590555e-3
GO:0019933	cAMP-mediated signaling	1.590941e-3
GO:0000018	regulation of DNA recombination	1.595383e-3
GO:0006813	potassium ion transport	1.597058e-3
GO:0034113	heterotypic cell-cell adhesion	1.615080e-3
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.616254e-3
GO:0006658	phosphatidylserine metabolic process	1.617258e-3
GO:0008228	opsonization	1.626369e-3
GO:0035037	sperm entry	1.666315e-3
GO:0042118	endothelial cell activation	1.670430e-3
GO:0032224	positive regulation of synaptic transmission, cholinergic	1.709032e-3
GO:0050790	regulation of catalytic activity	1.717959e-3
GO:0021782	glial cell development	1.774443e-3
GO:0030801	positive regulation of cyclic nucleotide metabolic process	1.779209e-3
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.784438e-3
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.784438e-3
GO:0031000	response to caffeine	1.790089e-3
GO:0090184	positive regulation of kidney development	1.791476e-3
GO:0006790	sulfur compound metabolic process	1.853345e-3
GO:0008285	negative regulation of cell proliferation	1.854332e-3
GO:0002903	negative regulation of B cell apoptosis	1.859583e-3
GO:0010975	regulation of neuron projection development	1.863969e-3
GO:0065009	regulation of molecular function	1.870262e-3
GO:0021536	diencephalon development	1.885305e-3
GO:0006573	valine metabolic process	1.888501e-3
GO:0032674	regulation of interleukin-5 production	1.889148e-3
GO:0032459	regulation of protein oligomerization	1.889148e-3
GO:0009231	riboflavin biosynthetic process	1.898280e-3
GO:0009743	response to carbohydrate stimulus	1.936925e-3
GO:0006928	cellular component movement	1.938755e-3
GO:0014075	response to amine stimulus	1.958312e-3
GO:0010886	positive regulation of cholesterol storage	1.964007e-3
GO:0006855	drug transmembrane transport	1.970196e-3
GO:0045822	negative regulation of heart contraction	1.972747e-3
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.979476e-3
GO:0055069	zinc ion homeostasis	1.983243e-3
GO:0001782	B cell homeostasis	1.985985e-3
GO:0018410	C-terminal protein amino acid modification	2.004603e-3
GO:0071805	potassium ion transmembrane transport	2.027510e-3
GO:0042446	hormone biosynthetic process	2.044600e-3
GO:0043480	pigment accumulation in tissues	2.058523e-3
GO:0009101	glycoprotein biosynthetic process	2.084913e-3
GO:0033151	V(D)J recombination	2.090886e-3
GO:0001914	regulation of T cell mediated cytotoxicity	2.107188e-3
GO:0060900	embryonic camera-type eye formation	2.108265e-3
GO:0090193	positive regulation of glomerulus development	2.112155e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	2.112155e-3
GO:0070661	leukocyte proliferation	2.129344e-3
GO:0043068	positive regulation of programmed cell death	2.134227e-3
GO:0007159	leukocyte cell-cell adhesion	2.140344e-3
GO:0034614	cellular response to reactive oxygen species	2.141880e-3
GO:0046327	glycerol biosynthetic process from pyruvate	2.156451e-3
GO:0019543	propionate catabolic process	2.156451e-3
GO:0000041	transition metal ion transport	2.166438e-3
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	2.179368e-3
GO:0006650	glycerophospholipid metabolic process	2.201293e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	2.214493e-3
GO:0090285	negative regulation of protein glycosylation in Golgi	2.227150e-3
GO:0019452	L-cysteine catabolic process to taurine	2.227150e-3
GO:0010942	positive regulation of cell death	2.261426e-3
GO:0050708	regulation of protein secretion	2.304451e-3