Novel motif:113

name:	motif113_YGAGCTRTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0033572	transferrin transport	2.154145e-12
GO:0046500	S-adenosylmethionine metabolic process	3.503826e-8
GO:0045007	depurination	7.878207e-8
GO:0002577	regulation of antigen processing and presentation	1.538575e-7
GO:0006826	iron ion transport	6.986785e-7
GO:0031440	regulation of mRNA 3'-end processing	8.036405e-7
GO:0007035	vacuolar acidification	1.007635e-6
GO:0070932	histone H3 deacetylation	1.125275e-6
GO:0001502	cartilage condensation	1.382018e-6
GO:0002579	positive regulation of antigen processing and presentation	1.704422e-6
GO:0043542	endothelial cell migration	2.034271e-6
GO:0006556	S-adenosylmethionine biosynthetic process	2.480096e-6
GO:0031442	positive regulation of mRNA 3'-end processing	3.150406e-6
GO:0046129	purine ribonucleoside biosynthetic process	3.308374e-6
GO:0002604	regulation of dendritic cell antigen processing and presentation	4.042336e-6
GO:0070933	histone H4 deacetylation	5.505327e-6
GO:0010107	potassium ion import	7.016713e-6
GO:0014874	response to stimulus involved in regulation of muscle adaptation	8.964219e-6
GO:0010987	negative regulation of high-density lipoprotein particle clearance	9.612460e-6
GO:0010897	negative regulation of triglyceride catabolic process	9.612460e-6
GO:0018095	protein polyglutamylation	1.045522e-5
GO:0046394	carboxylic acid biosynthetic process	1.083798e-5
GO:0048505	regulation of timing of cell differentiation	1.206696e-5
GO:0050684	regulation of mRNA processing	1.347589e-5
GO:0034983	peptidyl-lysine deacetylation	1.447296e-5
GO:0045820	negative regulation of glycolysis	1.571093e-5
GO:0009155	purine deoxyribonucleotide catabolic process	2.177784e-5
GO:0009151	purine deoxyribonucleotide metabolic process	2.287508e-5
GO:0034465	response to carbon monoxide	2.743569e-5
GO:0042866	pyruvate biosynthetic process	3.165341e-5
GO:0030327	prenylated protein catabolic process	3.235023e-5
GO:0001990	regulation of systemic arterial blood pressure by hormone	3.402907e-5
GO:0046654	tetrahydrofolate biosynthetic process	3.423099e-5
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	4.252513e-5
GO:0030826	regulation of cGMP biosynthetic process	4.376671e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.835012e-5
GO:0030201	heparan sulfate proteoglycan metabolic process	5.266043e-5
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	5.338205e-5
GO:0045355	negative regulation of interferon-alpha biosynthetic process	5.444084e-5
GO:0014916	regulation of lung blood pressure	6.267808e-5
GO:0051241	negative regulation of multicellular organismal process	6.890657e-5
GO:0006029	proteoglycan metabolic process	6.898778e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	7.263564e-5
GO:0035725	sodium ion transmembrane transport	7.416093e-5
GO:0015991	ATP hydrolysis coupled proton transport	7.501907e-5
GO:0034767	positive regulation of ion transmembrane transport	7.524952e-5
GO:0003300	cardiac muscle hypertrophy	7.868720e-5
GO:0055012	ventricular cardiac muscle cell differentiation	8.233352e-5
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	9.654945e-5
GO:0009712	catechol-containing compound metabolic process	9.683710e-5
GO:0061072	iris morphogenesis	9.800768e-5
GO:0010509	polyamine homeostasis	1.013383e-4
GO:0046642	negative regulation of alpha-beta T cell proliferation	1.080134e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.092971e-4
GO:0046628	positive regulation of insulin receptor signaling pathway	1.298717e-4
GO:0070613	regulation of protein processing	1.305825e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.321840e-4
GO:0009308	amine metabolic process	1.333724e-4
GO:0032488	Cdc42 protein signal transduction	1.334036e-4
GO:0045606	positive regulation of epidermal cell differentiation	1.340221e-4
GO:0009309	amine biosynthetic process	1.471619e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.514715e-4
GO:0006584	catecholamine metabolic process	1.519754e-4
GO:0006349	regulation of gene expression by genetic imprinting	1.637816e-4
GO:0051788	response to misfolded protein	1.751259e-4
GO:0050913	sensory perception of bitter taste	1.780960e-4
GO:0007166	cell surface receptor linked signaling pathway	1.785864e-4
GO:0031272	regulation of pseudopodium assembly	1.831200e-4
GO:0032695	negative regulation of interleukin-12 production	1.953063e-4
GO:0006913	nucleocytoplasmic transport	2.066999e-4
GO:0002922	positive regulation of humoral immune response	2.104712e-4
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	2.292219e-4
GO:0019323	pentose catabolic process	2.349637e-4
GO:0051066	dihydrobiopterin metabolic process	2.374504e-4
GO:0070861	regulation of protein exit from endoplasmic reticulum	2.384673e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.446747e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	2.524365e-4
GO:0044283	small molecule biosynthetic process	2.543535e-4
GO:0021905	forebrain-midbrain boundary formation	2.603078e-4
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	2.603078e-4
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	2.603078e-4
GO:0003322	pancreatic A cell development	2.603078e-4
GO:0031274	positive regulation of pseudopodium assembly	2.652384e-4
GO:2000273	positive regulation of receptor activity	2.798680e-4
GO:0060048	cardiac muscle contraction	2.893447e-4
GO:0042278	purine nucleoside metabolic process	2.928167e-4
GO:0002885	positive regulation of hypersensitivity	2.975090e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.119409e-4
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	3.221470e-4
GO:0006537	glutamate biosynthetic process	3.241495e-4
GO:0002904	positive regulation of B cell apoptosis	3.344584e-4
GO:0008634	negative regulation of survival gene product expression	3.347265e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	3.348815e-4
GO:0031648	protein destabilization	3.536465e-4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.597328e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	3.660723e-4
GO:0042345	regulation of NF-kappaB import into nucleus	3.676439e-4
GO:0014894	response to denervation involved in regulation of muscle adaptation	3.756886e-4
GO:0051005	negative regulation of lipoprotein lipase activity	3.756886e-4
GO:0042137	sequestering of neurotransmitter	3.780626e-4
GO:0046128	purine ribonucleoside metabolic process	3.907095e-4
GO:0002920	regulation of humoral immune response	3.929819e-4
GO:0055015	ventricular cardiac muscle cell development	3.948557e-4
GO:0060491	regulation of cell projection assembly	3.962716e-4
GO:0044106	cellular amine metabolic process	4.099979e-4
GO:0006955	immune response	4.165167e-4
GO:0010765	positive regulation of sodium ion transport	4.177942e-4
GO:0050855	regulation of B cell receptor signaling pathway	4.257631e-4
GO:0007422	peripheral nervous system development	4.291105e-4
GO:0051169	nuclear transport	4.318418e-4
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.480139e-4
GO:0014896	muscle hypertrophy	4.491649e-4
GO:0008652	cellular amino acid biosynthetic process	4.562246e-4
GO:0006690	icosanoid metabolic process	4.650847e-4
GO:0070543	response to linoleic acid	4.651173e-4
GO:0034696	response to prostaglandin F stimulus	4.651173e-4
GO:0019303	D-ribose catabolic process	4.651173e-4
GO:0010933	positive regulation of macrophage tolerance induction	4.651173e-4
GO:0060419	heart growth	4.695410e-4
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	4.925455e-4
GO:0006879	cellular iron ion homeostasis	5.016873e-4
GO:0001970	positive regulation of activation of membrane attack complex	5.230514e-4
GO:0090209	negative regulation of triglyceride metabolic process	5.243214e-4
GO:0035644	phosphoanandamide dephosphorylation	5.275178e-4
GO:0030449	regulation of complement activation	5.284797e-4
GO:0002016	regulation of blood volume by renin-angiotensin	5.458900e-4
GO:0030858	positive regulation of epithelial cell differentiation	5.485258e-4
GO:0006476	protein deacetylation	5.489299e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	5.752668e-4
GO:0033559	unsaturated fatty acid metabolic process	5.812590e-4
GO:0071514	genetic imprinting	5.897029e-4
GO:2000107	negative regulation of leukocyte apoptosis	5.917180e-4
GO:0050685	positive regulation of mRNA processing	5.984143e-4
GO:0015807	L-amino acid transport	6.049797e-4
GO:0045087	innate immune response	6.117866e-4
GO:0060337	type I interferon-mediated signaling pathway	6.226174e-4
GO:0032020	ISG15-protein conjugation	6.272530e-4
GO:0034340	response to type I interferon	6.325732e-4
GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	6.377617e-4
GO:0010758	regulation of macrophage chemotaxis	6.430206e-4
GO:0002902	regulation of B cell apoptosis	6.449162e-4
GO:0015893	drug transport	6.459145e-4
GO:0072197	ureter morphogenesis	7.008056e-4
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	7.008056e-4
GO:0060742	epithelial cell differentiation involved in prostate gland development	7.044238e-4
GO:0030166	proteoglycan biosynthetic process	7.094195e-4
GO:0006805	xenobiotic metabolic process	7.352827e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	7.355751e-4
GO:0030277	maintenance of gastrointestinal epithelium	7.421690e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	7.736085e-4
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	8.002319e-4
GO:0035262	gonad morphogenesis	8.187431e-4
GO:0010985	negative regulation of lipoprotein particle clearance	8.361573e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	8.455108e-4
GO:0002407	dendritic cell chemotaxis	8.474261e-4
GO:0032455	nerve growth factor processing	8.517412e-4
GO:0055017	cardiac muscle tissue growth	8.544240e-4
GO:0006406	mRNA export from nucleus	8.683238e-4
GO:0043330	response to exogenous dsRNA	8.799235e-4
GO:0003015	heart process	8.808865e-4
GO:0009082	branched chain family amino acid biosynthetic process	8.965231e-4
GO:0035601	protein deacylation	8.971846e-4
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	8.998392e-4
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	8.998392e-4
GO:0003415	chondrocyte hypertrophy	8.998392e-4
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	8.998392e-4
GO:0035622	intrahepatic bile duct development	8.998392e-4
GO:0019100	male germ-line sex determination	8.998392e-4
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	9.077844e-4
GO:0061049	cell growth involved in cardiac muscle cell development	9.077844e-4
GO:0002344	B cell affinity maturation	9.077844e-4
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	9.077844e-4
GO:0003331	positive regulation of extracellular matrix constituent secretion	9.077844e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	9.089174e-4
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	9.160618e-4
GO:0046724	oxalic acid secretion	9.314594e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	9.314594e-4
GO:0090232	positive regulation of spindle checkpoint	9.362344e-4
GO:0045792	negative regulation of cell size	9.362344e-4
GO:0002883	regulation of hypersensitivity	9.441749e-4
GO:0042136	neurotransmitter biosynthetic process	9.488513e-4
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	9.534749e-4
GO:0045760	positive regulation of action potential	9.608992e-4
GO:0006607	NLS-bearing substrate import into nucleus	9.858057e-4
GO:0050747	positive regulation of lipoprotein metabolic process	1.001471e-3
GO:0070372	regulation of ERK1 and ERK2 cascade	1.005475e-3
GO:0044272	sulfur compound biosynthetic process	1.006405e-3
GO:0007263	nitric oxide mediated signal transduction	1.009104e-3
GO:0006555	methionine metabolic process	1.011090e-3
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	1.022190e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	1.031723e-3
GO:0034776	response to histamine	1.038216e-3
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.104911e-3
GO:0035089	establishment of apical/basal cell polarity	1.121779e-3
GO:0014898	cardiac muscle hypertrophy in response to stress	1.138305e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	1.149099e-3
GO:0042423	catecholamine biosynthetic process	1.209596e-3
GO:0071731	response to nitric oxide	1.219091e-3
GO:0006538	glutamate catabolic process	1.223509e-3
GO:0010759	positive regulation of macrophage chemotaxis	1.226905e-3
GO:0006285	base-excision repair, AP site formation	1.253384e-3
GO:0015074	DNA integration	1.257562e-3
GO:0060433	bronchus development	1.272516e-3
GO:0006952	defense response	1.309443e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.319136e-3
GO:0071459	protein localization to chromosome, centromeric region	1.329460e-3
GO:0002355	detection of tumor cell	1.329460e-3
GO:0030220	platelet formation	1.332627e-3
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.347648e-3
GO:0050884	neuromuscular process controlling posture	1.376088e-3
GO:0009065	glutamine family amino acid catabolic process	1.376323e-3
GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	1.398697e-3
GO:0055025	positive regulation of cardiac muscle tissue development	1.401871e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.432814e-3
GO:0071466	cellular response to xenobiotic stimulus	1.441682e-3
GO:0006621	protein retention in ER lumen	1.461875e-3
GO:0000387	spliceosomal snRNP assembly	1.514803e-3
GO:2001014	regulation of skeletal muscle cell differentiation	1.514803e-3
GO:0010832	negative regulation of myotube differentiation	1.515890e-3
GO:0042147	retrograde transport, endosome to Golgi	1.522957e-3
GO:0051403	stress-activated MAPK cascade	1.533856e-3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	1.534534e-3
GO:0018076	N-terminal peptidyl-lysine acetylation	1.541336e-3
GO:0003084	positive regulation of systemic arterial blood pressure	1.542272e-3
GO:0052565	response to defense-related host nitric oxide production	1.576625e-3
GO:0003051	angiotensin-mediated drinking behavior	1.576625e-3
GO:0043691	reverse cholesterol transport	1.585455e-3
GO:0015886	heme transport	1.657088e-3
GO:0007538	primary sex determination	1.678742e-3
GO:0043090	amino acid import	1.697529e-3
GO:0030823	regulation of cGMP metabolic process	1.706009e-3
GO:0021798	forebrain dorsal/ventral pattern formation	1.718644e-3
GO:0042053	regulation of dopamine metabolic process	1.737990e-3
GO:2000106	regulation of leukocyte apoptosis	1.759204e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	1.790850e-3
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.799852e-3
GO:0090231	regulation of spindle checkpoint	1.816914e-3
GO:0010955	negative regulation of protein processing	1.831968e-3
GO:0033700	phospholipid efflux	1.850070e-3
GO:0060480	lung goblet cell differentiation	1.858038e-3
GO:0009435	NAD biosynthetic process	1.859722e-3
GO:0008050	female courtship behavior	1.870246e-3
GO:0032418	lysosome localization	1.889053e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.938095e-3
GO:0006405	RNA export from nucleus	1.956681e-3
GO:0019883	antigen processing and presentation of endogenous antigen	1.966771e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	1.986029e-3
GO:0071622	regulation of granulocyte chemotaxis	2.026406e-3
GO:0035691	macrophage migration inhibitory factor signaling pathway	2.084977e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	2.129312e-3
GO:2000020	positive regulation of male gonad development	2.162009e-3
GO:0061384	heart trabecular morphogenesis	2.162009e-3
GO:0051225	spindle assembly	2.174712e-3
GO:0010613	positive regulation of cardiac muscle hypertrophy	2.195934e-3
GO:0060729	intestinal epithelial structure maintenance	2.208210e-3
GO:0033126	positive regulation of GTP catabolic process	2.208210e-3
GO:0045862	positive regulation of proteolysis	2.230638e-3
GO:0002739	regulation of cytokine secretion involved in immune response	2.260416e-3
GO:0051170	nuclear import	2.313538e-3
GO:0070947	neutrophil mediated killing of fungus	2.320615e-3
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	2.320615e-3
GO:0050710	negative regulation of cytokine secretion	2.362500e-3
GO:0006474	N-terminal protein amino acid acetylation	2.365872e-3
GO:0043502	regulation of muscle adaptation	2.451122e-3
GO:0033002	muscle cell proliferation	2.460702e-3
GO:0032914	positive regulation of transforming growth factor beta1 production	2.475476e-3
GO:0070914	UV-damage excision repair	2.486255e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.490288e-3
GO:0048311	mitochondrion distribution	2.502011e-3
GO:0008065	establishment of blood-nerve barrier	2.543077e-3
GO:0046456	icosanoid biosynthetic process	2.576931e-3
GO:0042069	regulation of catecholamine metabolic process	2.717155e-3
GO:0003073	regulation of systemic arterial blood pressure	2.734522e-3
GO:0002645	positive regulation of tolerance induction	2.791279e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	2.791279e-3
GO:0009410	response to xenobiotic stimulus	2.893583e-3
GO:0035166	post-embryonic hemopoiesis	2.991657e-3
GO:0021796	cerebral cortex regionalization	3.020213e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	3.020213e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	3.056329e-3
GO:0031663	lipopolysaccharide-mediated signaling pathway	3.088675e-3
GO:0006769	nicotinamide metabolic process	3.094120e-3
GO:0046655	folic acid metabolic process	3.094120e-3
GO:0019511	peptidyl-proline hydroxylation	3.140281e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	3.167378e-3
GO:0006636	unsaturated fatty acid biosynthetic process	3.183823e-3
GO:0008272	sulfate transport	3.194422e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	3.201504e-3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	3.207085e-3
GO:0060134	prepulse inhibition	3.252157e-3
GO:0006540	glutamate decarboxylation to succinate	3.341299e-3
GO:0097022	lymphocyte migration into lymph node	3.341299e-3
GO:0050713	negative regulation of interleukin-1 beta secretion	3.341299e-3
GO:0006509	membrane protein ectodomain proteolysis	3.343343e-3
GO:0010751	negative regulation of nitric oxide mediated signal transduction	3.389660e-3
GO:0043652	engulfment of apoptotic cell	3.389660e-3
GO:0010754	negative regulation of cGMP-mediated signaling	3.389660e-3
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	3.389660e-3
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.389660e-3
GO:0060047	heart contraction	3.420594e-3
GO:0006692	prostanoid metabolic process	3.457170e-3
GO:0031329	regulation of cellular catabolic process	3.461776e-3
GO:0002906	negative regulation of mature B cell apoptosis	3.470828e-3
GO:0051665	membrane raft localization	3.470828e-3
GO:0042537	benzene-containing compound metabolic process	3.477869e-3
GO:0070228	regulation of lymphocyte apoptosis	3.528746e-3
GO:0030802	regulation of cyclic nucleotide biosynthetic process	3.559567e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	3.596850e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	3.596850e-3
GO:0043249	erythrocyte maturation	3.597891e-3
GO:0050883	musculoskeletal movement, spinal reflex action	3.713406e-3
GO:0006571	tyrosine biosynthetic process	3.713406e-3
GO:0031161	phosphatidylinositol catabolic process	3.713406e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.719191e-3
GO:0032908	regulation of transforming growth factor beta1 production	3.726289e-3
GO:0034341	response to interferon-gamma	3.745193e-3
GO:0090307	spindle assembly involved in mitosis	3.814837e-3
GO:0030206	chondroitin sulfate biosynthetic process	3.814977e-3
GO:0007619	courtship behavior	3.832307e-3
GO:0014902	myotube differentiation	3.853653e-3
GO:0038027	apolipoprotein A-I-mediated signaling pathway	3.922585e-3
GO:0006520	cellular amino acid metabolic process	3.929324e-3
GO:2000018	regulation of male gonad development	3.929350e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	3.973005e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	4.035998e-3
GO:0072233	metanephric thick ascending limb development	4.038627e-3
GO:0072218	metanephric ascending thin limb development	4.038627e-3
GO:0001778	plasma membrane repair	4.041432e-3
GO:0060221	retinal rod cell differentiation	4.045813e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	4.052964e-3
GO:0006885	regulation of pH	4.055708e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	4.069353e-3
GO:0050690	regulation of defense response to virus by virus	4.078358e-3
GO:0071675	regulation of mononuclear cell migration	4.139126e-3
GO:0048755	branching morphogenesis of a nerve	4.168887e-3
GO:0030162	regulation of proteolysis	4.214303e-3
GO:0002408	myeloid dendritic cell chemotaxis	4.349802e-3
GO:0072610	interleukin-12 secretion	4.349802e-3
GO:0035914	skeletal muscle cell differentiation	4.374782e-3
GO:0045986	negative regulation of smooth muscle contraction	4.377529e-3
GO:0060414	aorta smooth muscle tissue morphogenesis	4.384084e-3
GO:0006606	protein import into nucleus	4.398593e-3
GO:0006691	leukotriene metabolic process	4.414801e-3
GO:0060621	negative regulation of cholesterol import	4.420495e-3
GO:0071260	cellular response to mechanical stimulus	4.461539e-3
GO:0032463	negative regulation of protein homooligomerization	4.470323e-3
GO:0007173	epidermal growth factor receptor signaling pathway	4.499655e-3
GO:0035556	intracellular signal transduction	4.561875e-3
GO:0003139	secondary heart field specification	4.601003e-3
GO:0015031	protein transport	4.675522e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	4.684267e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	4.723432e-3
GO:0006957	complement activation, alternative pathway	4.751146e-3
GO:0070229	negative regulation of lymphocyte apoptosis	4.784431e-3
GO:0006633	fatty acid biosynthetic process	4.838725e-3
GO:0010757	negative regulation of plasminogen activation	4.952049e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.966324e-3
GO:0070498	interleukin-1-mediated signaling pathway	4.997829e-3
GO:0046960	sensitization	5.032183e-3
GO:0043148	mitotic spindle stabilization	5.032183e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	5.058514e-3
GO:0006090	pyruvate metabolic process	5.058514e-3
GO:0043092	L-amino acid import	5.082250e-3
GO:0030183	B cell differentiation	5.165891e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	5.177721e-3
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	5.181118e-3
GO:0006576	cellular biogenic amine metabolic process	5.236152e-3
GO:0006865	amino acid transport	5.255913e-3
GO:0048711	positive regulation of astrocyte differentiation	5.297990e-3
GO:0002347	response to tumor cell	5.330840e-3
GO:0031331	positive regulation of cellular catabolic process	5.345158e-3
GO:0048144	fibroblast proliferation	5.430388e-3
GO:0030828	positive regulation of cGMP biosynthetic process	5.532394e-3
GO:0019370	leukotriene biosynthetic process	5.572921e-3
GO:0090023	positive regulation of neutrophil chemotaxis	5.729051e-3
GO:0006891	intra-Golgi vesicle-mediated transport	5.738826e-3
GO:0010934	macrophage cytokine production	5.848836e-3
GO:0009108	coenzyme biosynthetic process	5.864400e-3
GO:0002339	B cell selection	5.872849e-3
GO:0045906	negative regulation of vasoconstriction	5.873893e-3
GO:0010621	negative regulation of transcription by transcription factor localization	5.930391e-3
GO:0022011	myelination in peripheral nervous system	5.949655e-3
GO:0051489	regulation of filopodium assembly	6.024520e-3
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	6.032448e-3
GO:0018958	phenol-containing compound metabolic process	6.062806e-3
GO:0030502	negative regulation of bone mineralization	6.078575e-3
GO:0050886	endocrine process	6.108997e-3
GO:0042416	dopamine biosynthetic process	6.124349e-3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	6.158043e-3
GO:0060125	negative regulation of growth hormone secretion	6.230958e-3
GO:0051463	negative regulation of cortisol secretion	6.230958e-3
GO:0006867	asparagine transport	6.230958e-3
GO:0000088	mitotic prophase	6.230958e-3
GO:0051084	'de novo' posttranslational protein folding	6.243908e-3
GO:0016575	histone deacetylation	6.255224e-3
GO:0045346	regulation of MHC class II biosynthetic process	6.306889e-3
GO:0045981	positive regulation of nucleotide metabolic process	6.357307e-3
GO:0002467	germinal center formation	6.363125e-3
GO:0048873	homeostasis of number of cells within a tissue	6.365549e-3
GO:0070417	cellular response to cold	6.521087e-3
GO:0009191	ribonucleoside diphosphate catabolic process	6.521087e-3
GO:0060347	heart trabecula formation	6.536839e-3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	6.541303e-3
GO:0007224	smoothened signaling pathway	6.578402e-3
GO:0006458	'de novo' protein folding	6.578402e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	6.768315e-3
GO:0034653	retinoic acid catabolic process	6.781455e-3
GO:0006140	regulation of nucleotide metabolic process	6.791387e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	6.866675e-3
GO:0007621	negative regulation of female receptivity	6.970164e-3
GO:0002067	glandular epithelial cell differentiation	7.020335e-3
GO:0009262	deoxyribonucleotide metabolic process	7.020781e-3
GO:0060333	interferon-gamma-mediated signaling pathway	7.032409e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.051213e-3
GO:0042417	dopamine metabolic process	7.121545e-3
GO:0007212	dopamine receptor signaling pathway	7.186324e-3
GO:0060164	regulation of timing of neuron differentiation	7.217038e-3
GO:0006433	prolyl-tRNA aminoacylation	7.263702e-3
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	7.293264e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	7.295009e-3
GO:0046680	response to DDT	7.295009e-3
GO:0071283	cellular response to iron(III) ion	7.295009e-3
GO:0060623	regulation of chromosome condensation	7.295009e-3
GO:0001519	peptide amidation	7.295009e-3
GO:0007113	endomitotic cell cycle	7.295009e-3
GO:0031860	telomeric 3' overhang formation	7.295009e-3
GO:0043456	regulation of pentose-phosphate shunt	7.295009e-3
GO:0009264	deoxyribonucleotide catabolic process	7.362143e-3
GO:0010984	regulation of lipoprotein particle clearance	7.407361e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	7.407361e-3
GO:0010874	regulation of cholesterol efflux	7.417270e-3
GO:0051016	barbed-end actin filament capping	7.478614e-3
GO:0045354	regulation of interferon-alpha biosynthetic process	7.522557e-3
GO:0002544	chronic inflammatory response	7.527325e-3
GO:0045924	regulation of female receptivity	7.649710e-3
GO:0002551	mast cell chemotaxis	7.730334e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	7.785551e-3
GO:0009820	alkaloid metabolic process	8.106635e-3
GO:0050711	negative regulation of interleukin-1 secretion	8.125050e-3
GO:0060620	regulation of cholesterol import	8.125050e-3
GO:0040030	regulation of molecular function, epigenetic	8.131473e-3
GO:0048193	Golgi vesicle transport	8.212146e-3
GO:0060482	lobar bronchus development	8.259815e-3
GO:0000041	transition metal ion transport	8.260775e-3
GO:0072236	metanephric loop of Henle development	8.267931e-3
GO:0060292	long term synaptic depression	8.362755e-3
GO:0044070	regulation of anion transport	8.362755e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	8.362755e-3
GO:0031330	negative regulation of cellular catabolic process	8.381805e-3
GO:0032606	type I interferon production	8.386501e-3
GO:0014816	satellite cell differentiation	8.441217e-3
GO:0010954	positive regulation of protein processing	8.453054e-3
GO:2000725	regulation of cardiac muscle cell differentiation	8.468760e-3
GO:0032922	circadian regulation of gene expression	8.518698e-3
GO:0001798	positive regulation of type IIa hypersensitivity	8.518698e-3
GO:0070286	axonemal dynein complex assembly	8.622043e-3
GO:0007206	activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway	8.622043e-3
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	8.629584e-3
GO:0002440	production of molecular mediator of immune response	8.654661e-3
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	8.672816e-3
GO:0006562	proline catabolic process	8.757764e-3
GO:0019060	intracellular transport of viral proteins in host cell	8.757764e-3
GO:0032414	positive regulation of ion transmembrane transporter activity	8.883110e-3
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	9.032137e-3
GO:0002035	brain renin-angiotensin system	9.032137e-3
GO:0007521	muscle cell fate determination	9.053138e-3
GO:0055091	phospholipid homeostasis	9.146264e-3
GO:0046532	regulation of photoreceptor cell differentiation	9.183912e-3
GO:0006353	transcription termination, DNA-dependent	9.294474e-3
GO:0048011	nerve growth factor receptor signaling pathway	9.313481e-3
GO:0034380	high-density lipoprotein particle assembly	9.338240e-3
GO:0018200	peptidyl-glutamic acid modification	9.356467e-3
GO:0050953	sensory perception of light stimulus	9.478626e-3
GO:0015837	amine transport	9.502642e-3
GO:0008016	regulation of heart contraction	9.542752e-3
GO:0002224	toll-like receptor signaling pathway	9.664679e-3
GO:0043982	histone H4-K8 acetylation	9.667585e-3
GO:0043981	histone H4-K5 acetylation	9.667585e-3
GO:0060009	Sertoli cell development	9.859359e-3
GO:0034762	regulation of transmembrane transport	9.883561e-3
GO:0007617	mating behavior	9.895124e-3
GO:0019752	carboxylic acid metabolic process	9.951633e-3
GO:0034499	late endosome to Golgi transport	1.001236e-2
GO:0071955	recycling endosome to Golgi transport	1.001236e-2
GO:0021759	globus pallidus development	1.001236e-2
GO:0060304	regulation of phosphatidylinositol dephosphorylation	1.002905e-2
GO:0034241	positive regulation of macrophage fusion	1.002905e-2
GO:0051932	synaptic transmission, GABAergic	1.002905e-2
GO:0042424	catecholamine catabolic process	1.006202e-2
GO:0032506	cytokinetic process	1.009594e-2
GO:0015872	dopamine transport	1.022548e-2
GO:0070849	response to epidermal growth factor stimulus	1.026124e-2
GO:0070168	negative regulation of biomineral tissue development	1.030836e-2
GO:0032787	monocarboxylic acid metabolic process	1.034388e-2
GO:0032376	positive regulation of cholesterol transport	1.037813e-2
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	1.037874e-2
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.037954e-2
GO:0042347	negative regulation of NF-kappaB import into nucleus	1.042665e-2
GO:0046968	peptide antigen transport	1.044395e-2
GO:0061036	positive regulation of cartilage development	1.048418e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0072166	posterior mesonephric tubule development	5.859992e-13
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	3.303653e-11
GO:2001076	positive regulation of metanephric ureteric bud development	3.303653e-11
GO:0007356	thorax and anterior abdomen determination	3.303653e-11
GO:0043503	skeletal muscle fiber adaptation	2.180020e-10
GO:0072125	negative regulation of glomerular mesangial cell proliferation	8.795001e-9
GO:0046498	S-adenosylhomocysteine metabolic process	1.919179e-8
GO:0051725	protein de-ADP-ribosylation	2.461955e-8
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.977747e-8
GO:0072015	glomerular visceral epithelial cell development	4.007521e-8
GO:0072124	regulation of glomerular mesangial cell proliferation	7.749351e-8
GO:0035802	adrenal cortex formation	9.013114e-8
GO:0032218	riboflavin transport	1.372684e-7
GO:0043501	skeletal muscle adaptation	8.462233e-7
GO:0034441	plasma lipoprotein particle oxidation	9.116048e-7
GO:0072284	metanephric S-shaped body morphogenesis	2.183425e-6
GO:0072278	metanephric comma-shaped body morphogenesis	2.183425e-6
GO:0051180	vitamin transport	2.477025e-6
GO:0045926	negative regulation of growth	3.146159e-6
GO:0021794	thalamus development	3.860643e-6
GO:0051973	positive regulation of telomerase activity	4.015767e-6
GO:0072298	regulation of metanephric glomerulus development	4.103761e-6
GO:0090192	regulation of glomerulus development	4.692545e-6
GO:0030308	negative regulation of cell growth	4.843369e-6
GO:0060539	diaphragm development	5.175314e-6
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	6.176175e-6
GO:0070483	detection of hypoxia	6.348771e-6
GO:0001920	negative regulation of receptor recycling	6.348771e-6
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	7.692007e-6
GO:0003032	detection of oxygen	7.735625e-6
GO:0060923	cardiac muscle cell fate commitment	8.378053e-6
GO:0048013	ephrin receptor signaling pathway	8.996166e-6
GO:0051403	stress-activated MAPK cascade	9.486602e-6
GO:0009119	ribonucleoside metabolic process	1.129921e-5
GO:0072215	regulation of metanephros development	1.393670e-5
GO:0071320	cellular response to cAMP	1.405617e-5
GO:0060911	cardiac cell fate commitment	1.466342e-5
GO:0046653	tetrahydrofolate metabolic process	1.541494e-5
GO:0007621	negative regulation of female receptivity	1.809584e-5
GO:0044246	regulation of multicellular organismal metabolic process	1.811635e-5
GO:0032728	positive regulation of interferon-beta production	1.916709e-5
GO:0044253	positive regulation of multicellular organismal metabolic process	2.175488e-5
GO:0006575	cellular modified amino acid metabolic process	2.728490e-5
GO:0060561	apoptosis involved in morphogenesis	3.280994e-5
GO:0032648	regulation of interferon-beta production	3.546252e-5
GO:0007354	zygotic determination of anterior/posterior axis, embryo	3.943220e-5
GO:0046395	carboxylic acid catabolic process	3.963398e-5
GO:0050999	regulation of nitric-oxide synthase activity	4.275358e-5
GO:2000194	regulation of female gonad development	4.931403e-5
GO:0032965	regulation of collagen biosynthetic process	5.357454e-5
GO:0002355	detection of tumor cell	5.561707e-5
GO:0009062	fatty acid catabolic process	5.616818e-5
GO:2000195	negative regulation of female gonad development	6.127264e-5
GO:0032967	positive regulation of collagen biosynthetic process	6.268092e-5
GO:0007172	signal complex assembly	6.964326e-5
GO:0072112	glomerular visceral epithelial cell differentiation	7.517665e-5
GO:0002021	response to dietary excess	7.658274e-5
GO:0016191	synaptic vesicle uncoating	8.027051e-5
GO:0090026	positive regulation of monocyte chemotaxis	8.787590e-5
GO:0001300	chronological cell aging	8.872731e-5
GO:0042219	cellular modified amino acid catabolic process	9.743210e-5
GO:0042447	hormone catabolic process	9.908596e-5
GO:0046850	regulation of bone remodeling	9.987508e-5
GO:0046452	dihydrofolate metabolic process	1.212090e-4
GO:0071105	response to interleukin-11	1.212090e-4
GO:0043500	muscle adaptation	1.248413e-4
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.309001e-4
GO:0006398	histone mRNA 3'-end processing	1.309001e-4
GO:0048389	intermediate mesoderm development	1.309001e-4
GO:0003241	growth involved in heart morphogenesis	1.425905e-4
GO:0040008	regulation of growth	1.447952e-4
GO:0046500	S-adenosylmethionine metabolic process	1.492426e-4
GO:0021860	pyramidal neuron development	1.555240e-4
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	1.562510e-4
GO:0060973	cell migration involved in heart development	1.611205e-4
GO:0045124	regulation of bone resorption	1.631098e-4
GO:0045082	positive regulation of interleukin-10 biosynthetic process	1.689725e-4
GO:0070278	extracellular matrix constituent secretion	1.712119e-4
GO:0010260	organ senescence	1.712119e-4
GO:0035644	phosphoanandamide dephosphorylation	1.714640e-4
GO:0070670	response to interleukin-4	1.848100e-4
GO:0001558	regulation of cell growth	1.903246e-4
GO:0014888	striated muscle adaptation	1.951546e-4
GO:0009116	nucleoside metabolic process	1.952918e-4
GO:0060231	mesenchymal to epithelial transition	2.036223e-4
GO:0030853	negative regulation of granulocyte differentiation	2.069385e-4
GO:0008050	female courtship behavior	2.133087e-4
GO:0003214	cardiac left ventricle morphogenesis	2.172482e-4
GO:0034446	substrate adhesion-dependent cell spreading	2.196326e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.240219e-4
GO:2000191	regulation of fatty acid transport	2.362132e-4
GO:0014028	notochord formation	2.476727e-4
GO:0002380	immunoglobulin secretion involved in immune response	2.476727e-4
GO:0003273	cell migration involved in endocardial cushion formation	2.476727e-4
GO:0072050	S-shaped body morphogenesis	2.708259e-4
GO:0072049	comma-shaped body morphogenesis	2.708259e-4
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2.863491e-4
GO:0032481	positive regulation of type I interferon production	3.062017e-4
GO:0000238	zygotene	3.169547e-4
GO:0046092	deoxycytidine metabolic process	3.181665e-4
GO:0061034	olfactory bulb mitral cell layer development	3.352471e-4
GO:0021884	forebrain neuron development	3.497272e-4
GO:0043366	beta selection	3.596260e-4
GO:0061005	cell differentiation involved in kidney development	3.624800e-4
GO:0090381	regulation of heart induction	3.815396e-4
GO:0015884	folic acid transport	3.839348e-4
GO:0022617	extracellular matrix disassembly	3.839348e-4
GO:0072355	histone H3-T3 phosphorylation	4.124965e-4
GO:0016042	lipid catabolic process	4.156816e-4
GO:0048741	skeletal muscle fiber development	4.171819e-4
GO:0001823	mesonephros development	4.250515e-4
GO:0009218	pyrimidine ribonucleotide metabolic process	4.916029e-4
GO:0042088	T-helper 1 type immune response	5.010881e-4
GO:0060421	positive regulation of heart growth	5.033595e-4
GO:0034103	regulation of tissue remodeling	5.101421e-4
GO:0090183	regulation of kidney development	5.163480e-4
GO:0072074	kidney mesenchyme development	5.342725e-4
GO:0060452	positive regulation of cardiac muscle contraction	5.424661e-4
GO:0070305	response to cGMP	5.507930e-4
GO:0021796	cerebral cortex regionalization	5.507930e-4
GO:0021542	dentate gyrus development	5.558739e-4
GO:2000018	regulation of male gonad development	6.086859e-4
GO:0072329	monocarboxylic acid catabolic process	6.209037e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	6.274484e-4
GO:0016078	tRNA catabolic process	6.274484e-4
GO:0001682	tRNA 5'-leader removal	6.274484e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	6.387813e-4
GO:0051591	response to cAMP	6.476582e-4
GO:0016082	synaptic vesicle priming	6.586800e-4
GO:0061032	visceral serous pericardium development	6.597926e-4
GO:0006213	pyrimidine nucleoside metabolic process	7.447079e-4
GO:0090185	negative regulation of kidney development	7.797042e-4
GO:0046128	purine ribonucleoside metabolic process	7.851994e-4
GO:0045089	positive regulation of innate immune response	8.138201e-4
GO:0045851	pH reduction	8.517679e-4
GO:0072190	ureter urothelium development	8.717997e-4
GO:0031427	response to methotrexate	8.880306e-4
GO:0030258	lipid modification	9.045883e-4
GO:0072164	mesonephric tubule development	9.279814e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.017315e-3
GO:0001937	negative regulation of endothelial cell proliferation	1.026474e-3
GO:0034059	response to anoxia	1.035074e-3
GO:0002220	innate immune response activating cell surface receptor signaling pathway	1.035074e-3
GO:0071247	cellular response to chromate	1.064028e-3
GO:2000020	positive regulation of male gonad development	1.119653e-3
GO:0035850	epithelial cell differentiation involved in kidney development	1.165676e-3
GO:0032479	regulation of type I interferon production	1.196414e-3
GO:0045601	regulation of endothelial cell differentiation	1.196414e-3
GO:0021935	cerebellar granule cell precursor tangential migration	1.201421e-3
GO:0006713	glucocorticoid catabolic process	1.201421e-3
GO:0006408	snRNA export from nucleus	1.201421e-3
GO:0046033	AMP metabolic process	1.219201e-3
GO:0032757	positive regulation of interleukin-8 production	1.243201e-3
GO:0007021	tubulin complex assembly	1.264454e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1.289282e-3
GO:0032753	positive regulation of interleukin-4 production	1.290055e-3
GO:0042404	thyroid hormone catabolic process	1.322972e-3
GO:0000578	embryonic axis specification	1.325005e-3
GO:0001881	receptor recycling	1.381130e-3
GO:0007618	mating	1.381176e-3
GO:2000377	regulation of reactive oxygen species metabolic process	1.434521e-3
GO:0051293	establishment of spindle localization	1.436205e-3
GO:0046851	negative regulation of bone remodeling	1.458320e-3
GO:0006760	folic acid-containing compound metabolic process	1.469579e-3
GO:0035993	deltoid tuberosity development	1.481683e-3
GO:0061072	iris morphogenesis	1.514212e-3
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	1.570167e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.570167e-3
GO:0034612	response to tumor necrosis factor	1.588856e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.594846e-3
GO:0021535	cell migration in hindbrain	1.645861e-3
GO:0007525	somatic muscle development	1.667015e-3
GO:0071674	mononuclear cell migration	1.680291e-3
GO:0034498	early endosome to Golgi transport	1.680291e-3
GO:0002432	granuloma formation	1.680291e-3
GO:0031529	ruffle organization	1.751411e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	1.759779e-3
GO:0007619	courtship behavior	1.759779e-3
GO:0000132	establishment of mitotic spindle orientation	1.806067e-3
GO:0072194	kidney smooth muscle tissue development	1.829298e-3
GO:0072273	metanephric nephron morphogenesis	1.869334e-3
GO:0090212	negative regulation of establishment of blood-brain barrier	1.896057e-3
GO:0015939	pantothenate metabolic process	1.896057e-3
GO:0051790	short-chain fatty acid biosynthetic process	1.896057e-3
GO:0050830	defense response to Gram-positive bacterium	1.920653e-3
GO:0021954	central nervous system neuron development	1.922406e-3
GO:0033057	multicellular organismal reproductive behavior	1.937037e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.941035e-3
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.972021e-3
GO:0072668	tubulin complex biogenesis	2.035303e-3
GO:0090231	regulation of spindle checkpoint	2.069075e-3
GO:0032069	regulation of nuclease activity	2.069075e-3
GO:0045046	protein import into peroxisome membrane	2.085122e-3
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	2.139307e-3
GO:0051099	positive regulation of binding	2.167309e-3
GO:0032863	activation of Rac GTPase activity	2.257552e-3
GO:0072208	metanephric smooth muscle tissue development	2.288560e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	2.288560e-3
GO:0072259	metanephric interstitial cell development	2.288560e-3
GO:0072168	specification of anterior mesonephric tubule identity	2.288560e-3
GO:0072169	specification of posterior mesonephric tubule identity	2.288560e-3
GO:0072184	renal vesicle progenitor cell differentiation	2.288560e-3
GO:0034374	low-density lipoprotein particle remodeling	2.333036e-3
GO:0045602	negative regulation of endothelial cell differentiation	2.367505e-3
GO:0050680	negative regulation of epithelial cell proliferation	2.488913e-3
GO:0009220	pyrimidine ribonucleotide biosynthetic process	2.526781e-3
GO:0001732	formation of translation initiation complex	2.541557e-3
GO:0006540	glutamate decarboxylation to succinate	2.611239e-3
GO:0046499	S-adenosylmethioninamine metabolic process	2.627275e-3
GO:0032817	regulation of natural killer cell proliferation	2.752925e-3
GO:0045768	positive regulation of anti-apoptosis	2.775839e-3
GO:0031122	cytoplasmic microtubule organization	2.804062e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	2.855118e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	2.868461e-3
GO:0031440	regulation of mRNA 3'-end processing	2.932142e-3
GO:0003382	epithelial cell morphogenesis	3.023803e-3
GO:0071872	cellular response to epinephrine stimulus	3.051236e-3
GO:0071548	response to dexamethasone stimulus	3.079040e-3
GO:0044242	cellular lipid catabolic process	3.090574e-3
GO:0003338	metanephros morphogenesis	3.121530e-3
GO:0032673	regulation of interleukin-4 production	3.121530e-3
GO:0034104	negative regulation of tissue remodeling	3.151897e-3
GO:0046833	positive regulation of RNA export from nucleus	3.195063e-3
GO:0008298	intracellular mRNA localization	3.211795e-3
GO:0021539	subthalamus development	3.211795e-3
GO:0060180	female mating behavior	3.214022e-3
GO:0034435	cholesterol esterification	3.214993e-3
GO:0001561	fatty acid alpha-oxidation	3.233008e-3
GO:0021905	forebrain-midbrain boundary formation	3.324812e-3
GO:0050975	sensory perception of touch	3.324812e-3
GO:0044205	'de novo' UMP biosynthetic process	3.324812e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	3.324812e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	3.324812e-3
GO:0003322	pancreatic A cell development	3.324812e-3
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	3.324812e-3
GO:0006603	phosphocreatine metabolic process	3.324812e-3
GO:0040001	establishment of mitotic spindle localization	3.354454e-3
GO:0048199	vesicle targeting, to, from or within Golgi	3.364798e-3
GO:0043388	positive regulation of DNA binding	3.414036e-3
GO:0033865	nucleoside bisphosphate metabolic process	3.461938e-3
GO:0007617	mating behavior	3.461938e-3
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	3.496759e-3
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	3.499606e-3
GO:0035556	intracellular signal transduction	3.632592e-3
GO:0009063	cellular amino acid catabolic process	3.752746e-3
GO:0033124	regulation of GTP catabolic process	3.791710e-3
GO:0032741	positive regulation of interleukin-18 production	3.834064e-3
GO:0008208	C21-steroid hormone catabolic process	3.834064e-3
GO:0030858	positive regulation of epithelial cell differentiation	3.838237e-3
GO:0046856	phosphatidylinositol dephosphorylation	3.851915e-3
GO:0072075	metanephric mesenchyme development	3.871693e-3
GO:0021549	cerebellum development	3.906625e-3
GO:0043087	regulation of GTPase activity	3.954604e-3
GO:0015893	drug transport	4.008763e-3
GO:0051649	establishment of localization in cell	4.043036e-3
GO:0030852	regulation of granulocyte differentiation	4.103070e-3
GO:0001867	complement activation, lectin pathway	4.184501e-3
GO:0003417	growth plate cartilage development	4.291469e-3
GO:0030865	cortical cytoskeleton organization	4.298079e-3
GO:0042147	retrograde transport, endosome to Golgi	4.333865e-3
GO:2000753	positive regulation of glucosylceramide catabolic process	4.334308e-3
GO:2000755	positive regulation of sphingomyelin catabolic process	4.334308e-3
GO:0034154	toll-like receptor 7 signaling pathway	4.334308e-3
GO:0032185	septin cytoskeleton organization	4.334308e-3
GO:0000053	argininosuccinate metabolic process	4.334308e-3
GO:0010966	regulation of phosphate transport	4.334308e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	4.342477e-3
GO:0048790	maintenance of presynaptic active zone structure	4.368657e-3
GO:0006844	acyl carnitine transport	4.368657e-3
GO:0015761	mannose transport	4.368657e-3
GO:0048015	phosphatidylinositol-mediated signaling	4.373239e-3
GO:0042278	purine nucleoside metabolic process	4.388826e-3
GO:0032677	regulation of interleukin-8 production	4.391959e-3
GO:0035434	copper ion transmembrane transport	4.433422e-3
GO:0019098	reproductive behavior	4.440802e-3
GO:0032075	positive regulation of nuclease activity	4.467929e-3
GO:0043048	dolichyl monophosphate biosynthetic process	4.468665e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	4.468665e-3
GO:0032680	regulation of tumor necrosis factor production	4.476112e-3
GO:0042662	negative regulation of mesodermal cell fate specification	4.568746e-3
GO:0045924	regulation of female receptivity	4.586855e-3
GO:0045779	negative regulation of bone resorption	4.592016e-3
GO:0072141	renal interstitial cell development	4.592648e-3
GO:0032319	regulation of Rho GTPase activity	4.631696e-3
GO:0043117	positive regulation of vascular permeability	4.637661e-3
GO:0010288	response to lead ion	4.659207e-3
GO:0044282	small molecule catabolic process	4.661044e-3
GO:0006528	asparagine metabolic process	4.764007e-3
GO:0032878	regulation of establishment or maintenance of cell polarity	4.948636e-3
GO:0005981	regulation of glycogen catabolic process	4.948636e-3
GO:2000304	positive regulation of ceramide biosynthetic process	4.953172e-3
GO:0006011	UDP-glucose metabolic process	4.953172e-3
GO:0051000	positive regulation of nitric-oxide synthase activity	5.037382e-3
GO:0010463	mesenchymal cell proliferation	5.039803e-3
GO:0015074	DNA integration	5.110231e-3
GO:0033628	regulation of cell adhesion mediated by integrin	5.193023e-3
GO:0045650	negative regulation of macrophage differentiation	5.411000e-3
GO:0016090	prenol metabolic process	5.413956e-3
GO:0031442	positive regulation of mRNA 3'-end processing	5.446328e-3
GO:0046600	negative regulation of centriole replication	5.656220e-3
GO:0006685	sphingomyelin catabolic process	5.656220e-3
GO:0045357	regulation of interferon-beta biosynthetic process	5.701612e-3
GO:0032855	positive regulation of Rac GTPase activity	5.747531e-3
GO:0051851	modification by host of symbiont morphology or physiology	5.794708e-3
GO:0046939	nucleotide phosphorylation	5.844492e-3
GO:0042136	neurotransmitter biosynthetic process	5.854917e-3
GO:0043491	protein kinase B signaling cascade	5.917123e-3
GO:0023021	termination of signal transduction	5.943979e-3
GO:0045780	positive regulation of bone resorption	6.022369e-3
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	6.108547e-3
GO:0015705	iodide transport	6.154743e-3
GO:0042694	muscle cell fate specification	6.154743e-3
GO:0071321	cellular response to cGMP	6.154743e-3
GO:0035095	behavioral response to nicotine	6.154743e-3
GO:0030421	defecation	6.174081e-3
GO:0009107	lipoate biosynthetic process	6.174081e-3
GO:0010822	positive regulation of mitochondrion organization	6.233108e-3
GO:0051452	intracellular pH reduction	6.305266e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	6.305266e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	6.306170e-3
GO:0051497	negative regulation of stress fiber assembly	6.427610e-3
GO:0006222	UMP biosynthetic process	6.427610e-3
GO:0051972	regulation of telomerase activity	6.564583e-3
GO:0009798	axis specification	6.590654e-3
GO:0006071	glycerol metabolic process	6.997125e-3
GO:0032091	negative regulation of protein binding	7.041432e-3
GO:0019439	aromatic compound catabolic process	7.090910e-3
GO:0061004	pattern specification involved in kidney development	7.183470e-3
GO:0046599	regulation of centriole replication	7.194129e-3
GO:0010755	regulation of plasminogen activation	7.217407e-3
GO:0048305	immunoglobulin secretion	7.223841e-3
GO:0001892	embryonic placenta development	7.268681e-3
GO:0032318	regulation of Ras GTPase activity	7.281398e-3
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	7.333449e-3
GO:0002575	basophil chemotaxis	7.333449e-3
GO:0035990	tendon cell differentiation	7.333449e-3
GO:0019400	alditol metabolic process	7.419383e-3
GO:0045638	negative regulation of myeloid cell differentiation	7.477062e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	7.516345e-3
GO:0060993	kidney morphogenesis	7.599611e-3
GO:0050778	positive regulation of immune response	7.846881e-3
GO:0032717	negative regulation of interleukin-8 production	7.924863e-3
GO:0032202	telomere assembly	7.951926e-3
GO:0008595	anterior/posterior axis specification, embryo	8.004883e-3
GO:0030240	skeletal muscle thin filament assembly	8.009323e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	8.034312e-3
GO:0006855	drug transmembrane transport	8.034312e-3
GO:0006887	exocytosis	8.087977e-3
GO:0072028	nephron morphogenesis	8.127289e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	8.141996e-3
GO:0046504	glycerol ether biosynthetic process	8.154054e-3
GO:0002034	regulation of blood vessel size by renin-angiotensin	8.180934e-3
GO:0009161	ribonucleoside monophosphate metabolic process	8.236944e-3
GO:0032656	regulation of interleukin-13 production	8.306141e-3
GO:0034276	kynurenic acid biosynthetic process	8.330291e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	8.330291e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	8.330291e-3
GO:0006517	protein deglycosylation	8.330291e-3
GO:0040010	positive regulation of growth rate	8.330291e-3
GO:0003259	cardioblast anterior-lateral migration	8.330291e-3
GO:0002534	cytokine production involved in inflammatory response	8.330291e-3
GO:0003243	circumferential growth involved in left ventricle morphogenesis	8.330291e-3
GO:0003210	cardiac atrium formation	8.330291e-3
GO:0003236	sinus venosus morphogenesis	8.330291e-3
GO:0070926	regulation of ATP:ADP antiporter activity	8.499443e-3
GO:0042407	cristae formation	8.499443e-3
GO:0032835	glomerulus development	8.580333e-3
GO:0010159	specification of organ position	8.600638e-3
GO:0010757	negative regulation of plasminogen activation	8.643039e-3
GO:0030194	positive regulation of blood coagulation	8.713144e-3
GO:0046839	phospholipid dephosphorylation	8.938174e-3
GO:0043687	post-translational protein modification	9.249754e-3
GO:0021978	telencephalon regionalization	9.249754e-3
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	9.426254e-3
GO:0051549	positive regulation of keratinocyte migration	9.426254e-3
GO:0051030	snRNA transport	9.431851e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	9.431851e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	9.458974e-3
GO:0060711	labyrinthine layer development	9.480363e-3
GO:0007032	endosome organization	9.510768e-3
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	9.584452e-3
GO:0032720	negative regulation of tumor necrosis factor production	9.898484e-3
GO:0071549	cellular response to dexamethasone stimulus	9.922579e-3
GO:0014866	skeletal myofibril assembly	1.002513e-2
GO:0034440	lipid oxidation	1.006087e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	1.013749e-2
GO:0022037	metencephalon development	1.014464e-2
GO:0030856	regulation of epithelial cell differentiation	1.015643e-2
GO:0035767	endothelial cell chemotaxis	1.018943e-2
GO:0030828	positive regulation of cGMP biosynthetic process	1.024902e-2
GO:0030011	maintenance of cell polarity	1.027132e-2
GO:0006405	RNA export from nucleus	1.045178e-2
GO:0050829	defense response to Gram-negative bacterium	1.046349e-2
GO:0042697	menopause	1.048159e-2
GO:0043697	cell dedifferentiation	1.048159e-2
GO:0032661	regulation of interleukin-18 production	1.048159e-2
GO:0002536	respiratory burst involved in inflammatory response	1.048159e-2
GO:0006917	induction of apoptosis	1.056845e-2
GO:0019285	glycine betaine biosynthetic process from choline	1.059249e-2
GO:0071318	cellular response to ATP	1.059249e-2
GO:0006383	transcription from RNA polymerase III promoter	1.059249e-2
GO:0010890	positive regulation of sequestering of triglyceride	1.059249e-2
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.082663e-2
GO:0060712	spongiotrophoblast layer development	1.083712e-2
GO:0051127	positive regulation of actin nucleation	1.087878e-2
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.087878e-2
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.087878e-2
GO:0070318	positive regulation of G0 to G1 transition	1.089234e-2
GO:2000114	regulation of establishment of cell polarity	1.109992e-2
GO:0042403	thyroid hormone metabolic process	1.125437e-2
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	1.138931e-2
GO:0046903	secretion	1.165899e-2
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1.166010e-2
GO:0034097	response to cytokine stimulus	1.184060e-2
GO:0045356	positive regulation of interferon-alpha biosynthetic process	1.195339e-2
GO:0072229	metanephric proximal convoluted tubule development	1.195339e-2
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.195339e-2
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	1.200416e-2
GO:0045989	positive regulation of striated muscle contraction	1.206806e-2
GO:0030902	hindbrain development	1.218000e-2
GO:0012502	induction of programmed cell death	1.245756e-2
GO:0034770	histone H4-K20 methylation	1.245857e-2
GO:0003416	endochondral bone growth	1.248581e-2
GO:0034105	positive regulation of tissue remodeling	1.265724e-2
GO:0006284	base-excision repair	1.268569e-2
GO:0040009	regulation of growth rate	1.279902e-2
GO:0019255	glucose 1-phosphate metabolic process	1.279902e-2
GO:0090184	positive regulation of kidney development	1.323105e-2
GO:0060215	primitive hemopoiesis	1.345768e-2
GO:0043547	positive regulation of GTPase activity	1.363454e-2
GO:0031943	regulation of glucocorticoid metabolic process	1.373239e-2
GO:0007220	Notch receptor processing	1.373239e-2
GO:0048505	regulation of timing of cell differentiation	1.377159e-2
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	1.378589e-2
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	1.378589e-2
GO:0072198	mesenchymal cell proliferation involved in ureter development	1.378589e-2
GO:0072192	ureter epithelial cell differentiation	1.378589e-2
GO:0090194	negative regulation of glomerulus development	1.378589e-2
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	1.378589e-2
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	1.378589e-2
GO:2000639	negative regulation of SREBP-mediated signaling pathway	1.378589e-2
GO:2000346	negative regulation of hepatocyte proliferation	1.378589e-2
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	1.378589e-2
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	1.378589e-2
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	1.378589e-2
GO:0007500	mesodermal cell fate determination	1.378589e-2
GO:0055020	positive regulation of cardiac muscle fiber development	1.378589e-2
GO:0050747	positive regulation of lipoprotein metabolic process	1.378589e-2
GO:0048392	intermediate mesodermal cell differentiation	1.378589e-2
GO:0006481	C-terminal protein methylation	1.378589e-2
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	1.378589e-2
GO:0060503	bud dilation involved in lung branching	1.378589e-2
GO:0071893	BMP signaling pathway involved in nephric duct formation	1.378589e-2
GO:0061155	pulmonary artery endothelial tube morphogenesis	1.378589e-2
GO:0061151	BMP signaling pathway involved in renal system segmentation	1.378589e-2
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	1.378589e-2
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	1.378589e-2
GO:0051453	regulation of intracellular pH	1.383606e-2
GO:0006167	AMP biosynthetic process	1.406583e-2
GO:0045074	regulation of interleukin-10 biosynthetic process	1.414931e-2
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.419985e-2
GO:0008156	negative regulation of DNA replication	1.423971e-2
GO:0001840	neural plate development	1.449781e-2
GO:0042048	olfactory behavior	1.452729e-2
GO:0009258	10-formyltetrahydrofolate catabolic process	1.452729e-2
GO:0030070	insulin processing	1.452729e-2
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.457664e-2
GO:0071104	response to interleukin-9	1.471033e-2
GO:0052063	induction by symbiont of defense-related host nitric oxide production	1.471033e-2
GO:2000001	regulation of DNA damage checkpoint	1.471033e-2
GO:0002551	mast cell chemotaxis	1.471033e-2
GO:0040040	thermosensory behavior	1.471033e-2
GO:0042892	chloramphenicol transport	1.471033e-2
GO:0032321	positive regulation of Rho GTPase activity	1.476175e-2
GO:0034332	adherens junction organization	1.501425e-2
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	1.502207e-2
GO:0002218	activation of innate immune response	1.510478e-2
GO:0051918	negative regulation of fibrinolysis	1.549644e-2
GO:0060125	negative regulation of growth hormone secretion	1.566672e-2
GO:0071217	cellular response to external biotic stimulus	1.566672e-2
GO:0080164	regulation of nitric oxide metabolic process	1.566672e-2
GO:0051792	medium-chain fatty acid biosynthetic process	1.566672e-2
GO:0070684	seminal clot liquefaction	1.566672e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.566672e-2
GO:0051463	negative regulation of cortisol secretion	1.566672e-2
GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	1.566672e-2
GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	1.566672e-2
GO:0002223	stimulatory C-type lectin receptor signaling pathway	1.566672e-2
GO:0032320	positive regulation of Ras GTPase activity	1.578544e-2
GO:0010623	developmental programmed cell death	1.584564e-2
GO:0010951	negative regulation of endopeptidase activity	1.588745e-2
GO:0009948	anterior/posterior axis specification	1.593392e-2
GO:0072210	metanephric nephron development	1.607449e-2
GO:0051186	cofactor metabolic process	1.612371e-2
GO:0070542	response to fatty acid	1.615080e-2
GO:0031532	actin cytoskeleton reorganization	1.685896e-2
GO:0035865	cellular response to potassium ion	1.690927e-2
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.690927e-2
GO:0071896	protein localization to adherens junction	1.690927e-2
GO:0090274	positive regulation of somatostatin secretion	1.690927e-2