Novel motif:137

name:	motif137_MAACAGAAGY

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0045087	innate immune response	1.352782e-9
GO:0060586	multicellular organismal iron ion homeostasis	1.743869e-9
GO:0006928	cellular component movement	2.212545e-9
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	3.298702e-9
GO:0035684	helper T cell extravasation	3.600439e-9
GO:0018149	peptide cross-linking	5.310548e-9
GO:0002548	monocyte chemotaxis	5.728645e-9
GO:0009611	response to wounding	1.861183e-8
GO:0030032	lamellipodium assembly	3.053973e-8
GO:0007155	cell adhesion	4.805041e-8
GO:0006952	defense response	8.172662e-8
GO:0006944	cellular membrane fusion	8.853257e-8
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	1.612866e-7
GO:0006955	immune response	1.630651e-7
GO:0002769	natural killer cell inhibitory signaling pathway	1.826021e-7
GO:0061025	membrane fusion	2.257913e-7
GO:0043616	keratinocyte proliferation	2.925860e-7
GO:0002253	activation of immune response	3.714470e-7
GO:0006954	inflammatory response	4.385629e-7
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4.784666e-7
GO:0030595	leukocyte chemotaxis	4.898491e-7
GO:0048247	lymphocyte chemotaxis	7.221236e-7
GO:0007131	reciprocal meiotic recombination	9.812758e-7
GO:0042699	follicle-stimulating hormone signaling pathway	1.258259e-6
GO:0006166	purine ribonucleoside salvage	1.538789e-6
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	1.620059e-6
GO:0001562	response to protozoan	2.206579e-6
GO:0010966	regulation of phosphate transport	2.300453e-6
GO:0006828	manganese ion transport	2.623788e-6
GO:0032509	endosome transport via multivesicular body sorting pathway	3.247878e-6
GO:0045110	intermediate filament bundle assembly	3.352965e-6
GO:0002224	toll-like receptor signaling pathway	4.449496e-6
GO:0034142	toll-like receptor 4 signaling pathway	4.633468e-6
GO:0072668	tubulin complex biogenesis	4.932406e-6
GO:0002274	myeloid leukocyte activation	5.111592e-6
GO:0006936	muscle contraction	5.222642e-6
GO:0006950	response to stress	5.700597e-6
GO:0034341	response to interferon-gamma	5.708207e-6
GO:0034130	toll-like receptor 1 signaling pathway	6.301945e-6
GO:0034134	toll-like receptor 2 signaling pathway	6.301945e-6
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	7.221288e-6
GO:0048646	anatomical structure formation involved in morphogenesis	8.061005e-6
GO:0030216	keratinocyte differentiation	8.122155e-6
GO:0002218	activation of innate immune response	9.662627e-6
GO:0000279	M phase	9.698716e-6
GO:0032570	response to progesterone stimulus	9.874017e-6
GO:0048285	organelle fission	1.004271e-5
GO:0070252	actin-mediated cell contraction	1.142093e-5
GO:0042832	defense response to protozoan	1.143165e-5
GO:0045342	MHC class II biosynthetic process	1.209760e-5
GO:0070839	divalent metal ion export	1.209760e-5
GO:0043091	L-arginine import	1.209760e-5
GO:0015707	nitrite transport	1.209760e-5
GO:0006876	cellular cadmium ion homeostasis	1.209760e-5
GO:0032632	interleukin-3 production	1.209760e-5
GO:0033552	response to vitamin B3	1.329584e-5
GO:0001938	positive regulation of endothelial cell proliferation	1.339843e-5
GO:0030049	muscle filament sliding	1.426352e-5
GO:0002376	immune system process	1.454718e-5
GO:0060429	epithelium development	1.529453e-5
GO:0009913	epidermal cell differentiation	1.577747e-5
GO:0032438	melanosome organization	1.668665e-5
GO:0070417	cellular response to cold	1.676322e-5
GO:0007018	microtubule-based movement	1.712696e-5
GO:0060345	spleen trabecula formation	1.798895e-5
GO:0015980	energy derivation by oxidation of organic compounds	1.842156e-5
GO:0060271	cilium morphogenesis	1.854708e-5
GO:0043615	astrocyte cell migration	1.918652e-5
GO:0044058	regulation of digestive system process	1.964579e-5
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	2.034234e-5
GO:0000087	M phase of mitotic cell cycle	2.264217e-5
GO:0007021	tubulin complex assembly	2.265645e-5
GO:0045089	positive regulation of innate immune response	2.300664e-5
GO:0033993	response to lipid	2.321491e-5
GO:0071731	response to nitric oxide	2.482929e-5
GO:0002765	immune response-inhibiting signal transduction	2.624617e-5
GO:0033693	neurofilament bundle assembly	2.640959e-5
GO:0043094	cellular metabolic compound salvage	2.699714e-5
GO:0030168	platelet activation	2.722492e-5
GO:0002764	immune response-regulating signaling pathway	2.734379e-5
GO:0042116	macrophage activation	2.748565e-5
GO:0014823	response to activity	2.758206e-5
GO:0030031	cell projection assembly	2.797095e-5
GO:0010565	regulation of cellular ketone metabolic process	2.839407e-5
GO:0002246	wound healing involved in inflammatory response	2.902302e-5
GO:0070673	response to interleukin-18	2.971082e-5
GO:0006555	methionine metabolic process	2.996373e-5
GO:0035262	gonad morphogenesis	3.066392e-5
GO:0042118	endothelial cell activation	3.198910e-5
GO:0072676	lymphocyte migration	3.214519e-5
GO:0010592	positive regulation of lamellipodium assembly	3.257804e-5
GO:0034198	cellular response to amino acid starvation	3.297029e-5
GO:0009066	aspartate family amino acid metabolic process	3.448675e-5
GO:0001654	eye development	3.644221e-5
GO:0008090	retrograde axon cargo transport	3.663734e-5
GO:0060019	radial glial cell differentiation	3.771703e-5
GO:0042060	wound healing	3.803196e-5
GO:0070098	chemokine-mediated signaling pathway	3.816879e-5
GO:0048284	organelle fusion	3.817844e-5
GO:0051403	stress-activated MAPK cascade	3.833650e-5
GO:0072678	T cell migration	4.026113e-5
GO:0008593	regulation of Notch signaling pathway	4.147626e-5
GO:0021680	cerebellar Purkinje cell layer development	4.278454e-5
GO:0002758	innate immune response-activating signal transduction	4.432167e-5
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	4.608504e-5
GO:0030862	positive regulation of polarized epithelial cell differentiation	4.782577e-5
GO:0045333	cellular respiration	4.816444e-5
GO:0071228	cellular response to tumor cell	5.028506e-5
GO:0008063	Toll signaling pathway	5.172050e-5
GO:0050778	positive regulation of immune response	5.382536e-5
GO:0001736	establishment of planar polarity	5.401866e-5
GO:0006906	vesicle fusion	5.409039e-5
GO:0000236	mitotic prometaphase	5.642133e-5
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	5.658486e-5
GO:0031109	microtubule polymerization or depolymerization	5.860569e-5
GO:0043519	regulation of myosin II filament organization	6.049280e-5
GO:0006091	generation of precursor metabolites and energy	6.088116e-5
GO:0019932	second-messenger-mediated signaling	6.319226e-5
GO:0044093	positive regulation of molecular function	6.452575e-5
GO:0007067	mitosis	6.516857e-5
GO:0003012	muscle system process	6.550345e-5
GO:0021575	hindbrain morphogenesis	6.565460e-5
GO:0009086	methionine biosynthetic process	6.652790e-5
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6.826615e-5
GO:0002221	pattern recognition receptor signaling pathway	6.878966e-5
GO:0002757	immune response-activating signal transduction	6.945434e-5
GO:0030301	cholesterol transport	7.079902e-5
GO:0015918	sterol transport	7.269605e-5
GO:0071346	cellular response to interferon-gamma	7.475462e-5
GO:0006168	adenine salvage	8.012615e-5
GO:0002309	T cell proliferation involved in immune response	8.060569e-5
GO:0046464	acylglycerol catabolic process	8.401624e-5
GO:0009888	tissue development	8.464473e-5
GO:0019509	L-methionine salvage from methylthioadenosine	8.478249e-5
GO:0046689	response to mercury ion	8.532284e-5
GO:0051293	establishment of spindle localization	8.568292e-5
GO:0031032	actomyosin structure organization	8.701364e-5
GO:0046503	glycerolipid catabolic process	8.729903e-5
GO:0002462	tolerance induction to nonself antigen	9.045161e-5
GO:0035434	copper ion transmembrane transport	9.135750e-5
GO:0014866	skeletal myofibril assembly	9.312405e-5
GO:0001936	regulation of endothelial cell proliferation	9.354853e-5
GO:0051788	response to misfolded protein	9.681214e-5
GO:0006711	estrogen catabolic process	9.697574e-5
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	9.706007e-5
GO:0022904	respiratory electron transport chain	9.708579e-5
GO:0019896	axon transport of mitochondrion	1.002218e-4
GO:0043330	response to exogenous dsRNA	1.005994e-4
GO:0006188	IMP biosynthetic process	1.057752e-4
GO:0046548	retinal rod cell development	1.121354e-4
GO:0010970	microtubule-based transport	1.145100e-4
GO:0035092	sperm chromatin condensation	1.152048e-4
GO:0032472	Golgi calcium ion transport	1.237264e-4
GO:0070286	axonemal dynein complex assembly	1.237264e-4
GO:0032468	Golgi calcium ion homeostasis	1.237264e-4
GO:0030026	cellular manganese ion homeostasis	1.237264e-4
GO:0043101	purine-containing compound salvage	1.267718e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.270457e-4
GO:0035883	enteroendocrine cell differentiation	1.328508e-4
GO:0021861	forebrain radial glial cell differentiation	1.351037e-4
GO:0007164	establishment of tissue polarity	1.359904e-4
GO:0040001	establishment of mitotic spindle localization	1.386580e-4
GO:0033059	cellular pigmentation	1.440949e-4
GO:0030029	actin filament-based process	1.498096e-4
GO:0000132	establishment of mitotic spindle orientation	1.525560e-4
GO:0032494	response to peptidoglycan	1.550381e-4
GO:0043331	response to dsRNA	1.555946e-4
GO:0001944	vasculature development	1.588893e-4
GO:0010507	negative regulation of autophagy	1.613176e-4
GO:0048520	positive regulation of behavior	1.669548e-4
GO:0021549	cerebellum development	1.684978e-4
GO:0000097	sulfur amino acid biosynthetic process	1.686228e-4
GO:0050906	detection of stimulus involved in sensory perception	1.721048e-4
GO:0030573	bile acid catabolic process	1.762771e-4
GO:0007163	establishment or maintenance of cell polarity	1.773926e-4
GO:0031424	keratinization	1.782731e-4
GO:0060137	maternal process involved in parturition	1.825637e-4
GO:0060191	regulation of lipase activity	1.845584e-4
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	1.853683e-4
GO:0022403	cell cycle phase	1.906034e-4
GO:0030300	regulation of intestinal cholesterol absorption	1.926571e-4
GO:0014047	glutamate secretion	1.930678e-4
GO:0002827	positive regulation of T-helper 1 type immune response	1.935485e-4
GO:0007127	meiosis I	1.950298e-4
GO:0030431	sleep	2.001147e-4
GO:0022402	cell cycle process	2.001972e-4
GO:0050921	positive regulation of chemotaxis	2.027509e-4
GO:0090208	positive regulation of triglyceride metabolic process	2.038694e-4
GO:0051592	response to calcium ion	2.043421e-4
GO:0016358	dendrite development	2.063372e-4
GO:0009636	response to toxin	2.154850e-4
GO:0006111	regulation of gluconeogenesis	2.169869e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	2.230575e-4
GO:0035335	peptidyl-tyrosine dephosphorylation	2.262492e-4
GO:0002384	hepatic immune response	2.268588e-4
GO:0060561	apoptosis involved in morphogenesis	2.328064e-4
GO:0032966	negative regulation of collagen biosynthetic process	2.338746e-4
GO:0019079	viral genome replication	2.343300e-4
GO:0046716	muscle cell homeostasis	2.363581e-4
GO:0032623	interleukin-2 production	2.431943e-4
GO:0032375	negative regulation of cholesterol transport	2.431943e-4
GO:0070375	BMK cascade	2.447673e-4
GO:0065009	regulation of molecular function	2.461033e-4
GO:0046459	short-chain fatty acid metabolic process	2.475408e-4
GO:0021987	cerebral cortex development	2.522020e-4
GO:0006996	organelle organization	2.529099e-4
GO:0030705	cytoskeleton-dependent intracellular transport	2.579374e-4
GO:0042992	negative regulation of transcription factor import into nucleus	2.694618e-4
GO:0003056	regulation of vascular smooth muscle contraction	2.700784e-4
GO:0002688	regulation of leukocyte chemotaxis	2.712553e-4
GO:0051004	regulation of lipoprotein lipase activity	2.762183e-4
GO:0001568	blood vessel development	2.766228e-4
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	2.817644e-4
GO:0051646	mitochondrion localization	2.857147e-4
GO:0050776	regulation of immune response	2.922091e-4
GO:0030299	intestinal cholesterol absorption	2.922884e-4
GO:0006089	lactate metabolic process	2.970472e-4
GO:0071844	cellular component assembly at cellular level	3.035876e-4
GO:0042574	retinal metabolic process	3.036828e-4
GO:0030241	skeletal muscle myosin thick filament assembly	3.059530e-4
GO:0051209	release of sequestered calcium ion into cytosol	3.071491e-4
GO:0030036	actin cytoskeleton organization	3.107201e-4
GO:0046928	regulation of neurotransmitter secretion	3.116262e-4
GO:0007017	microtubule-based process	3.226397e-4
GO:0009409	response to cold	3.481990e-4
GO:0007166	cell surface receptor linked signaling pathway	3.507708e-4
GO:0032263	GMP salvage	3.521100e-4
GO:0032264	IMP salvage	3.521100e-4
GO:0019433	triglyceride catabolic process	3.588066e-4
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	3.640145e-4
GO:0010666	positive regulation of cardiac muscle cell apoptosis	3.666932e-4
GO:0015809	arginine transport	3.670152e-4
GO:0060326	cell chemotaxis	3.729933e-4
GO:0043438	acetoacetic acid metabolic process	3.812326e-4
GO:0051282	regulation of sequestering of calcium ion	3.837643e-4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	3.883026e-4
GO:0007406	negative regulation of neuroblast proliferation	3.907656e-4
GO:0071224	cellular response to peptidoglycan	4.007077e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	4.054012e-4
GO:0042461	photoreceptor cell development	4.092675e-4
GO:0071732	cellular response to nitric oxide	4.092685e-4
GO:0048739	cardiac muscle fiber development	4.190332e-4
GO:0071674	mononuclear cell migration	4.249129e-4
GO:0010623	developmental programmed cell death	4.609791e-4
GO:0032463	negative regulation of protein homooligomerization	4.721038e-4
GO:0051349	positive regulation of lyase activity	4.727687e-4
GO:0048747	muscle fiber development	4.783914e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	4.791829e-4
GO:0043010	camera-type eye development	4.888026e-4
GO:0006323	DNA packaging	4.907043e-4
GO:0008088	axon cargo transport	4.907707e-4
GO:0055001	muscle cell development	5.003638e-4
GO:0000096	sulfur amino acid metabolic process	5.004124e-4
GO:0010867	positive regulation of triglyceride biosynthetic process	5.070805e-4
GO:0060603	mammary gland duct morphogenesis	5.102395e-4
GO:0009067	aspartate family amino acid biosynthetic process	5.111590e-4
GO:0048753	pigment granule organization	5.198683e-4
GO:0021702	cerebellar Purkinje cell differentiation	5.235249e-4
GO:0033364	mast cell secretory granule organization	5.398873e-4
GO:0050920	regulation of chemotaxis	5.474287e-4
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	5.492509e-4
GO:0045762	positive regulation of adenylate cyclase activity	5.682324e-4
GO:0030048	actin filament-based movement	5.691703e-4
GO:0051782	negative regulation of cell division	5.779545e-4
GO:0050790	regulation of catalytic activity	5.891616e-4
GO:0090399	replicative senescence	5.967308e-4
GO:0042462	eye photoreceptor cell development	6.025552e-4
GO:0034382	chylomicron remnant clearance	6.030131e-4
GO:0090218	positive regulation of lipid kinase activity	6.108298e-4
GO:0034370	triglyceride-rich lipoprotein particle remodeling	6.202052e-4
GO:0045730	respiratory burst	6.242853e-4
GO:0070555	response to interleukin-1	6.255438e-4
GO:0006177	GMP biosynthetic process	6.400069e-4
GO:0043206	fibril organization	6.532410e-4
GO:0019217	regulation of fatty acid metabolic process	6.538383e-4
GO:0046677	response to antibiotic	6.686697e-4
GO:0045088	regulation of innate immune response	6.726838e-4
GO:0006626	protein targeting to mitochondrion	6.740184e-4
GO:0009615	response to virus	6.838141e-4
GO:0001837	epithelial to mesenchymal transition	6.861863e-4
GO:0034373	intermediate-density lipoprotein particle remodeling	6.883038e-4
GO:0051707	response to other organism	6.925122e-4
GO:0007289	spermatid nucleus differentiation	7.140433e-4
GO:0006638	neutral lipid metabolic process	7.222849e-4
GO:0007567	parturition	7.262810e-4
GO:0019605	butyrate metabolic process	7.363850e-4
GO:0035093	spermatogenesis, exchange of chromosomal proteins	7.416489e-4
GO:0002687	positive regulation of leukocyte migration	7.434716e-4
GO:0010713	negative regulation of collagen metabolic process	7.436588e-4
GO:0034764	positive regulation of transmembrane transport	7.567214e-4
GO:0055013	cardiac muscle cell development	7.584326e-4
GO:0042133	neurotransmitter metabolic process	7.608919e-4
GO:0035306	positive regulation of dephosphorylation	7.705477e-4
GO:0030902	hindbrain development	7.897420e-4
GO:0018904	organic ether metabolic process	8.013236e-4
GO:0021543	pallium development	8.067313e-4
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	8.298705e-4
GO:0050974	detection of mechanical stimulus involved in sensory perception	8.617334e-4
GO:0055093	response to hyperoxia	8.656627e-4
GO:0072277	metanephric glomerular capillary formation	8.765785e-4
GO:0051251	positive regulation of lymphocyte activation	8.892494e-4
GO:0035307	positive regulation of protein dephosphorylation	9.129868e-4
GO:0007423	sensory organ development	9.176083e-4
GO:0034638	phosphatidylcholine catabolic process	9.297596e-4
GO:0060443	mammary gland morphogenesis	9.548864e-4
GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	9.649081e-4
GO:0007179	transforming growth factor beta receptor signaling pathway	9.765128e-4
GO:0008089	anterograde axon cargo transport	9.772812e-4
GO:0048513	organ development	9.813229e-4
GO:0006605	protein targeting	1.003912e-3
GO:0010660	regulation of muscle cell apoptosis	1.004802e-3
GO:0002690	positive regulation of leukocyte chemotaxis	1.008145e-3
GO:0034441	plasma lipoprotein particle oxidation	1.015115e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.065925e-3
GO:0045109	intermediate filament organization	1.066281e-3
GO:0007160	cell-matrix adhesion	1.095214e-3
GO:0003108	negative regulation of the force of heart contraction by chemical signal	1.105564e-3
GO:2000366	positive regulation of STAT protein import into nucleus	1.120753e-3
GO:0070091	glucagon secretion	1.120753e-3
GO:0072358	cardiovascular system development	1.120775e-3
GO:0009987	cellular process	1.127799e-3
GO:0072110	glomerular mesangial cell proliferation	1.148857e-3
GO:0001775	cell activation	1.156890e-3
GO:0030239	myofibril assembly	1.199638e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	1.205322e-3
GO:0016476	regulation of embryonic cell shape	1.213770e-3
GO:0006975	DNA damage induced protein phosphorylation	1.223951e-3
GO:0031281	positive regulation of cyclase activity	1.230798e-3
GO:0034138	toll-like receptor 3 signaling pathway	1.237253e-3
GO:0007049	cell cycle	1.238683e-3
GO:0000278	mitotic cell cycle	1.251698e-3
GO:0038003	opioid receptor signaling pathway	1.252059e-3
GO:0044246	regulation of multicellular organismal metabolic process	1.253852e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.284668e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	1.296330e-3
GO:0010838	positive regulation of keratinocyte proliferation	1.296330e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	1.302178e-3
GO:0045746	negative regulation of Notch signaling pathway	1.302823e-3
GO:0032965	regulation of collagen biosynthetic process	1.328921e-3
GO:0007596	blood coagulation	1.331736e-3
GO:0007599	hemostasis	1.339320e-3
GO:0046931	pore complex assembly	1.342667e-3
GO:0009440	cyanate catabolic process	1.351033e-3
GO:0001774	microglial cell activation	1.351262e-3
GO:0071421	manganese ion transmembrane transport	1.361776e-3
GO:0050893	sensory processing	1.375067e-3
GO:0007059	chromosome segregation	1.406622e-3
GO:0001525	angiogenesis	1.409657e-3
GO:0050829	defense response to Gram-negative bacterium	1.492279e-3
GO:0022900	electron transport chain	1.496410e-3
GO:0009607	response to biotic stimulus	1.504209e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	1.517219e-3
GO:0007586	digestion	1.517602e-3
GO:0070541	response to platinum ion	1.519574e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	1.536828e-3
GO:0010332	response to gamma radiation	1.562602e-3
GO:0060086	circadian temperature homeostasis	1.577594e-3
GO:0032074	negative regulation of nuclease activity	1.577594e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	1.588801e-3
GO:0070574	cadmium ion transmembrane transport	1.609585e-3
GO:0031349	positive regulation of defense response	1.620213e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.665031e-3
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	1.665513e-3
GO:0043392	negative regulation of DNA binding	1.674680e-3
GO:0006611	protein export from nucleus	1.681083e-3
GO:0034622	cellular macromolecular complex assembly	1.690468e-3
GO:0019935	cyclic-nucleotide-mediated signaling	1.690500e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.703815e-3
GO:0031646	positive regulation of neurological system process	1.717551e-3
GO:0051298	centrosome duplication	1.719609e-3
GO:0021932	hindbrain radial glia guided cell migration	1.732496e-3
GO:0043085	positive regulation of catalytic activity	1.759341e-3
GO:0035051	cardiac cell differentiation	1.799626e-3
GO:0050878	regulation of body fluid levels	1.801156e-3
GO:0046475	glycerophospholipid catabolic process	1.808216e-3
GO:0052695	cellular glucuronidation	1.808657e-3
GO:0006629	lipid metabolic process	1.818946e-3
GO:0003096	renal sodium ion transport	1.830994e-3
GO:0072109	glomerular mesangium development	1.863041e-3
GO:0022037	metencephalon development	1.898193e-3
GO:0051303	establishment of chromosome localization	1.905457e-3
GO:0010927	cellular component assembly involved in morphogenesis	1.961236e-3
GO:0007184	SMAD protein import into nucleus	1.964360e-3
GO:0048514	blood vessel morphogenesis	1.966745e-3
GO:0043473	pigmentation	2.002339e-3
GO:0031115	negative regulation of microtubule polymerization	2.008350e-3
GO:0001738	morphogenesis of a polarized epithelium	2.019292e-3
GO:0043623	cellular protein complex assembly	2.027805e-3
GO:0051541	elastin metabolic process	2.035359e-3
GO:0051971	positive regulation of transmission of nerve impulse	2.074306e-3
GO:0021695	cerebellar cortex development	2.076975e-3
GO:0006664	glycolipid metabolic process	2.096799e-3
GO:0007035	vacuolar acidification	2.098524e-3
GO:0007190	activation of adenylate cyclase activity	2.110570e-3
GO:0021535	cell migration in hindbrain	2.113928e-3
GO:0042554	superoxide anion generation	2.128442e-3
GO:0071675	regulation of mononuclear cell migration	2.147835e-3
GO:0015872	dopamine transport	2.174575e-3
GO:0006435	threonyl-tRNA aminoacylation	2.182400e-3
GO:0010712	regulation of collagen metabolic process	2.207181e-3
GO:0010759	positive regulation of macrophage chemotaxis	2.220316e-3
GO:0010888	negative regulation of lipid storage	2.222261e-3
GO:0070661	leukocyte proliferation	2.274965e-3
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.286758e-3
GO:0010758	regulation of macrophage chemotaxis	2.287201e-3
GO:0007259	JAK-STAT cascade	2.294455e-3
GO:0021943	formation of radial glial scaffolds	2.313372e-3
GO:0010662	regulation of striated muscle cell apoptosis	2.325815e-3
GO:0006769	nicotinamide metabolic process	2.341931e-3
GO:0050982	detection of mechanical stimulus	2.349721e-3
GO:0035058	nonmotile primary cilium assembly	2.352135e-3
GO:0018208	peptidyl-proline modification	2.353941e-3
GO:0051336	regulation of hydrolase activity	2.363483e-3
GO:0000266	mitochondrial fission	2.466141e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	2.487658e-3
GO:0043004	cytoplasmic sequestering of CFTR protein	2.503157e-3
GO:0002369	T cell cytokine production	2.506288e-3
GO:0006639	acylglycerol metabolic process	2.507753e-3
GO:0045214	sarcomere organization	2.521608e-3
GO:0050908	detection of light stimulus involved in visual perception	2.546363e-3
GO:0046530	photoreceptor cell differentiation	2.584511e-3
GO:0071615	oxidative deethylation	2.587582e-3
GO:0009403	toxin biosynthetic process	2.587582e-3
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	2.587582e-3
GO:0006119	oxidative phosphorylation	2.596028e-3
GO:0002158	osteoclast proliferation	2.657845e-3
GO:0006665	sphingolipid metabolic process	2.673965e-3
GO:0015693	magnesium ion transport	2.676949e-3
GO:0002684	positive regulation of immune system process	2.705489e-3
GO:0006662	glycerol ether metabolic process	2.724689e-3
GO:0002237	response to molecule of bacterial origin	2.726265e-3
GO:0032364	oxygen homeostasis	2.738390e-3
GO:0030010	establishment of cell polarity	2.744514e-3
GO:0070294	renal sodium ion absorption	2.778380e-3
GO:0007525	somatic muscle development	2.812256e-3
GO:0010661	positive regulation of muscle cell apoptosis	2.812980e-3
GO:0050795	regulation of behavior	2.826703e-3
GO:0002696	positive regulation of leukocyte activation	2.838795e-3
GO:0060751	branch elongation involved in mammary gland duct branching	2.864131e-3
GO:0010591	regulation of lamellipodium assembly	2.923067e-3
GO:0055108	Golgi to transport vesicle transport	2.929840e-3
GO:0072006	nephron development	2.960902e-3
GO:0022607	cellular component assembly	2.966217e-3
GO:0051156	glucose 6-phosphate metabolic process	3.004277e-3
GO:0008544	epidermis development	3.023967e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	3.043048e-3
GO:0060621	negative regulation of cholesterol import	3.054156e-3
GO:0043923	positive regulation by host of viral transcription	3.075593e-3
GO:0060416	response to growth hormone stimulus	3.110129e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	3.158319e-3
GO:0060161	positive regulation of dopamine receptor signaling pathway	3.181952e-3
GO:0072655	establishment of protein localization in mitochondrion	3.186999e-3
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	3.219179e-3
GO:0071103	DNA conformation change	3.226845e-3
GO:0051640	organelle localization	3.245617e-3
GO:0002250	adaptive immune response	3.254030e-3
GO:0016050	vesicle organization	3.290614e-3
GO:0032317	regulation of Rap GTPase activity	3.302025e-3
GO:0048870	cell motility	3.327909e-3
GO:0006687	glycosphingolipid metabolic process	3.332255e-3
GO:0010573	vascular endothelial growth factor production	3.411304e-3
GO:0045785	positive regulation of cell adhesion	3.447936e-3
GO:0060333	interferon-gamma-mediated signaling pathway	3.492641e-3
GO:0035881	amacrine cell differentiation	3.541227e-3
GO:0010038	response to metal ion	3.554831e-3
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	3.561152e-3
GO:0017085	response to insecticide	3.565123e-3
GO:0001754	eye photoreceptor cell differentiation	3.595085e-3
GO:0021587	cerebellum morphogenesis	3.621319e-3
GO:0032496	response to lipopolysaccharide	3.629853e-3
GO:0044085	cellular component biogenesis	3.637484e-3
GO:0032801	receptor catabolic process	3.674879e-3
GO:0035418	protein localization to synapse	3.682253e-3
GO:0031113	regulation of microtubule polymerization	3.688831e-3
GO:0007229	integrin-mediated signaling pathway	3.690131e-3
GO:0050867	positive regulation of cell activation	3.699607e-3
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	3.702659e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	3.717075e-3
GO:0010863	positive regulation of phospholipase C activity	3.778241e-3
GO:0019511	peptidyl-proline hydroxylation	3.794665e-3
GO:0045606	positive regulation of epidermal cell differentiation	3.828819e-3
GO:0032455	nerve growth factor processing	3.828819e-3
GO:0021544	subpallium development	3.854814e-3
GO:0048312	intracellular distribution of mitochondria	3.890602e-3
GO:0031497	chromatin assembly	3.919311e-3
GO:0006916	anti-apoptosis	3.980029e-3
GO:0072355	histone H3-T3 phosphorylation	3.981710e-3
GO:0010734	negative regulation of protein glutathionylation	3.981710e-3
GO:0048213	Golgi vesicle prefusion complex stabilization	3.981710e-3
GO:0045091	regulation of retroviral genome replication	4.001524e-3
GO:0043691	reverse cholesterol transport	4.019910e-3
GO:0030240	skeletal muscle thin filament assembly	4.035285e-3
GO:0009152	purine ribonucleotide biosynthetic process	4.037076e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	4.050820e-3
GO:0006397	mRNA processing	4.097802e-3
GO:0010811	positive regulation of cell-substrate adhesion	4.100768e-3
GO:0032387	negative regulation of intracellular transport	4.104300e-3
GO:0007623	circadian rhythm	4.147187e-3
GO:0006677	glycosylceramide metabolic process	4.157678e-3
GO:0006643	membrane lipid metabolic process	4.185328e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006955	immune response	1.120600e-11
GO:0060621	negative regulation of cholesterol import	1.208519e-11
GO:0060620	regulation of cholesterol import	1.155394e-10
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.712154e-10
GO:0010897	negative regulation of triglyceride catabolic process	1.712154e-10
GO:0045329	carnitine biosynthetic process	1.940056e-10
GO:0002577	regulation of antigen processing and presentation	1.094608e-9
GO:0002478	antigen processing and presentation of exogenous peptide antigen	2.342298e-9
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	2.588939e-9
GO:0002252	immune effector process	4.997512e-9
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	6.235180e-9
GO:0001775	cell activation	1.100445e-8
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.207580e-8
GO:0051918	negative regulation of fibrinolysis	1.415947e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	1.486445e-8
GO:0048002	antigen processing and presentation of peptide antigen	1.681535e-8
GO:0006323	DNA packaging	1.778958e-8
GO:0050704	regulation of interleukin-1 secretion	1.803609e-8
GO:0030194	positive regulation of blood coagulation	2.895961e-8
GO:0045321	leukocyte activation	3.075747e-8
GO:0050776	regulation of immune response	3.143760e-8
GO:0009617	response to bacterium	3.314386e-8
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	3.341520e-8
GO:0033003	regulation of mast cell activation	3.870653e-8
GO:0050711	negative regulation of interleukin-1 secretion	4.076824e-8
GO:0034763	negative regulation of transmembrane transport	4.113988e-8
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.168449e-8
GO:0019884	antigen processing and presentation of exogenous antigen	5.489622e-8
GO:0006952	defense response	7.494923e-8
GO:0051050	positive regulation of transport	8.181160e-8
GO:0002376	immune system process	8.404217e-8
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	8.673713e-8
GO:0009607	response to biotic stimulus	9.218550e-8
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1.030888e-7
GO:2000147	positive regulation of cell motility	1.156169e-7
GO:0051272	positive regulation of cellular component movement	1.286870e-7
GO:0002702	positive regulation of production of molecular mediator of immune response	1.692923e-7
GO:0050706	regulation of interleukin-1 beta secretion	2.622111e-7
GO:0030335	positive regulation of cell migration	2.800058e-7
GO:0051346	negative regulation of hydrolase activity	3.206643e-7
GO:0018149	peptide cross-linking	3.334893e-7
GO:0051917	regulation of fibrinolysis	4.517212e-7
GO:0002579	positive regulation of antigen processing and presentation	5.229980e-7
GO:0051707	response to other organism	5.248908e-7
GO:0032369	negative regulation of lipid transport	5.756144e-7
GO:0051047	positive regulation of secretion	5.770491e-7
GO:0002682	regulation of immune system process	5.910694e-7
GO:0070257	positive regulation of mucus secretion	6.237934e-7
GO:0040017	positive regulation of locomotion	6.243383e-7
GO:0002720	positive regulation of cytokine production involved in immune response	6.446534e-7
GO:0009628	response to abiotic stimulus	6.942926e-7
GO:0002274	myeloid leukocyte activation	7.169479e-7
GO:0052547	regulation of peptidase activity	7.382016e-7
GO:0010763	positive regulation of fibroblast migration	7.560695e-7
GO:0001913	T cell mediated cytotoxicity	7.594697e-7
GO:0019882	antigen processing and presentation	8.012595e-7
GO:0010466	negative regulation of peptidase activity	8.492439e-7
GO:0050820	positive regulation of coagulation	8.572673e-7
GO:0051590	positive regulation of neurotransmitter transport	9.496969e-7
GO:0071103	DNA conformation change	1.007890e-6
GO:0002718	regulation of cytokine production involved in immune response	1.012611e-6
GO:0050804	regulation of synaptic transmission	1.103829e-6
GO:0003350	pulmonary myocardium development	1.109871e-6
GO:0032103	positive regulation of response to external stimulus	1.217901e-6
GO:0032026	response to magnesium ion	1.245884e-6
GO:0050713	negative regulation of interleukin-1 beta secretion	1.253514e-6
GO:0002684	positive regulation of immune system process	1.267440e-6
GO:0032375	negative regulation of cholesterol transport	1.655792e-6
GO:0032652	regulation of interleukin-1 production	1.819293e-6
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.886082e-6
GO:0050778	positive regulation of immune response	2.062279e-6
GO:0031497	chromatin assembly	2.330298e-6
GO:0034375	high-density lipoprotein particle remodeling	2.506129e-6
GO:0002700	regulation of production of molecular mediator of immune response	2.698128e-6
GO:0045576	mast cell activation	2.860057e-6
GO:0060346	bone trabecula formation	3.084097e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.237539e-6
GO:0010935	regulation of macrophage cytokine production	3.306341e-6
GO:0002821	positive regulation of adaptive immune response	3.339749e-6
GO:0032642	regulation of chemokine production	3.355729e-6
GO:0034341	response to interferon-gamma	3.517829e-6
GO:0060359	response to ammonium ion	3.593985e-6
GO:0006911	phagocytosis, engulfment	3.817121e-6
GO:0002739	regulation of cytokine secretion involved in immune response	4.590217e-6
GO:0035050	embryonic heart tube development	4.777352e-6
GO:0032368	regulation of lipid transport	5.253135e-6
GO:0002699	positive regulation of immune effector process	5.268411e-6
GO:0032101	regulation of response to external stimulus	5.426967e-6
GO:0046627	negative regulation of insulin receptor signaling pathway	5.428363e-6
GO:0051584	regulation of dopamine uptake	5.870463e-6
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.378996e-6
GO:0032651	regulation of interleukin-1 beta production	6.763381e-6
GO:0043536	positive regulation of blood vessel endothelial cell migration	8.060798e-6
GO:2000193	positive regulation of fatty acid transport	9.232950e-6
GO:0051969	regulation of transmission of nerve impulse	9.573847e-6
GO:0060907	positive regulation of macrophage cytokine production	9.599050e-6
GO:0050921	positive regulation of chemotaxis	1.002998e-5
GO:0050707	regulation of cytokine secretion	1.016114e-5
GO:0051046	regulation of secretion	1.072149e-5
GO:0002764	immune response-regulating signaling pathway	1.146930e-5
GO:0046632	alpha-beta T cell differentiation	1.168895e-5
GO:0051017	actin filament bundle assembly	1.244480e-5
GO:0051704	multi-organism process	1.290162e-5
GO:0022601	menstrual cycle phase	1.303093e-5
GO:0060921	sinoatrial node cell differentiation	1.527402e-5
GO:0032308	positive regulation of prostaglandin secretion	1.588457e-5
GO:0002344	B cell affinity maturation	1.588457e-5
GO:0051224	negative regulation of protein transport	1.700682e-5
GO:0002757	immune response-activating signal transduction	1.780736e-5
GO:0016601	Rac protein signal transduction	1.853278e-5
GO:0051004	regulation of lipoprotein lipase activity	1.948470e-5
GO:0046649	lymphocyte activation	1.980466e-5
GO:0009408	response to heat	2.028560e-5
GO:0048584	positive regulation of response to stimulus	2.054568e-5
GO:0044242	cellular lipid catabolic process	2.192092e-5
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.194697e-5
GO:0002366	leukocyte activation involved in immune response	2.239084e-5
GO:0035590	purinergic nucleotide receptor signaling pathway	2.264013e-5
GO:0090343	positive regulation of cell aging	2.417777e-5
GO:0031424	keratinization	2.524191e-5
GO:0050708	regulation of protein secretion	2.652525e-5
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	2.756956e-5
GO:2000191	regulation of fatty acid transport	2.848207e-5
GO:0032760	positive regulation of tumor necrosis factor production	3.220553e-5
GO:0031915	positive regulation of synaptic plasticity	3.288694e-5
GO:0021542	dentate gyrus development	3.308293e-5
GO:0032370	positive regulation of lipid transport	3.315409e-5
GO:0032943	mononuclear cell proliferation	3.381389e-5
GO:0015862	uridine transport	3.505044e-5
GO:0032859	activation of Ral GTPase activity	3.673454e-5
GO:0060931	sinoatrial node cell development	4.195679e-5
GO:0003167	atrioventricular bundle cell differentiation	4.195679e-5
GO:0070508	cholesterol import	4.515237e-5
GO:0050709	negative regulation of protein secretion	4.551165e-5
GO:0014012	peripheral nervous system axon regeneration	4.774145e-5
GO:0046651	lymphocyte proliferation	4.835021e-5
GO:0070661	leukocyte proliferation	4.852283e-5
GO:0090209	negative regulation of triglyceride metabolic process	4.945261e-5
GO:0046543	development of secondary female sexual characteristics	5.005790e-5
GO:0002237	response to molecule of bacterial origin	5.054575e-5
GO:0051580	regulation of neurotransmitter uptake	5.296841e-5
GO:0031644	regulation of neurological system process	5.313605e-5
GO:0051586	positive regulation of dopamine uptake	5.329120e-5
GO:0060192	negative regulation of lipase activity	5.417646e-5
GO:0042742	defense response to bacterium	5.533936e-5
GO:0021761	limbic system development	5.667875e-5
GO:0002819	regulation of adaptive immune response	5.673361e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	6.043741e-5
GO:0051005	negative regulation of lipoprotein lipase activity	6.141728e-5
GO:0001961	positive regulation of cytokine-mediated signaling pathway	6.141728e-5
GO:0070328	triglyceride homeostasis	6.165839e-5
GO:0002521	leukocyte differentiation	6.425223e-5
GO:0006642	triglyceride mobilization	6.585607e-5
GO:0006259	DNA metabolic process	6.671923e-5
GO:0045884	regulation of survival gene product expression	6.764367e-5
GO:0035621	ER to Golgi ceramide transport	6.803450e-5
GO:0080134	regulation of response to stress	6.836629e-5
GO:0035587	purinergic receptor signaling pathway	7.098053e-5
GO:0030300	regulation of intestinal cholesterol absorption	7.160824e-5
GO:0032722	positive regulation of chemokine production	7.456420e-5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	7.571536e-5
GO:0045843	negative regulation of striated muscle tissue development	7.798582e-5
GO:0008211	glucocorticoid metabolic process	7.859847e-5
GO:0010812	negative regulation of cell-substrate adhesion	8.214784e-5
GO:0060191	regulation of lipase activity	8.300082e-5
GO:0043086	negative regulation of catalytic activity	8.588210e-5
GO:0006333	chromatin assembly or disassembly	8.848427e-5
GO:0070848	response to growth factor stimulus	8.857152e-5
GO:0023061	signal release	8.899562e-5
GO:0002687	positive regulation of leukocyte migration	9.591651e-5
GO:0001959	regulation of cytokine-mediated signaling pathway	9.659033e-5
GO:0002339	B cell selection	1.002992e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.005949e-4
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.005949e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	1.017751e-4
GO:0003163	sinoatrial node development	1.025898e-4
GO:0007265	Ras protein signal transduction	1.044961e-4
GO:0010922	positive regulation of phosphatase activity	1.048672e-4
GO:0070208	protein heterotrimerization	1.086535e-4
GO:0002275	myeloid cell activation involved in immune response	1.094785e-4
GO:0010722	regulation of ferrochelatase activity	1.117062e-4
GO:0002286	T cell activation involved in immune response	1.155378e-4
GO:0050930	induction of positive chemotaxis	1.182897e-4
GO:0046631	alpha-beta T cell activation	1.240771e-4
GO:0060920	pacemaker cell differentiation	1.304844e-4
GO:0070255	regulation of mucus secretion	1.304844e-4
GO:0042713	sperm ejaculation	1.305083e-4
GO:0043589	skin morphogenesis	1.338152e-4
GO:0032374	regulation of cholesterol transport	1.376783e-4
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.426210e-4
GO:0060759	regulation of response to cytokine stimulus	1.470315e-4
GO:0003151	outflow tract morphogenesis	1.485189e-4
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.536744e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.539750e-4
GO:0002697	regulation of immune effector process	1.593303e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.636645e-4
GO:0071361	cellular response to ethanol	1.648174e-4
GO:0034382	chylomicron remnant clearance	1.659864e-4
GO:0046464	acylglycerol catabolic process	1.691592e-4
GO:0002253	activation of immune response	1.707405e-4
GO:0003166	bundle of His development	1.717013e-4
GO:0045921	positive regulation of exocytosis	1.726609e-4
GO:0042110	T cell activation	1.750099e-4
GO:0060760	positive regulation of response to cytokine stimulus	1.751098e-4
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	1.782677e-4
GO:0048341	paraxial mesoderm formation	1.852324e-4
GO:0032680	regulation of tumor necrosis factor production	1.879001e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	1.920703e-4
GO:0030431	sleep	1.955080e-4
GO:0002825	regulation of T-helper 1 type immune response	1.955080e-4
GO:0032892	positive regulation of organic acid transport	1.967333e-4
GO:0010595	positive regulation of endothelial cell migration	1.981118e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.987351e-4
GO:0035117	embryonic arm morphogenesis	2.062156e-4
GO:0033151	V(D)J recombination	2.073095e-4
GO:0030098	lymphocyte differentiation	2.105505e-4
GO:2000774	positive regulation of cellular senescence	2.150235e-4
GO:0090402	oncogene-induced senescence	2.150235e-4
GO:0035986	senescence-associated heterochromatin focus formation	2.150235e-4
GO:0071294	cellular response to zinc ion	2.150235e-4
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	2.247612e-4
GO:0031529	ruffle organization	2.258102e-4
GO:0071216	cellular response to biotic stimulus	2.313139e-4
GO:0043069	negative regulation of programmed cell death	2.344948e-4
GO:0045785	positive regulation of cell adhesion	2.377516e-4
GO:0050884	neuromuscular process controlling posture	2.421229e-4
GO:0034380	high-density lipoprotein particle assembly	2.421229e-4
GO:0043030	regulation of macrophage activation	2.613373e-4
GO:0032879	regulation of localization	2.622246e-4
GO:0048635	negative regulation of muscle organ development	2.672041e-4
GO:0006950	response to stress	2.676250e-4
GO:0050920	regulation of chemotaxis	2.717724e-4
GO:0035641	locomotory exploration behavior	2.734460e-4
GO:0015864	pyrimidine nucleoside transport	2.765386e-4
GO:0071346	cellular response to interferon-gamma	2.774462e-4
GO:0035282	segmentation	2.790970e-4
GO:0070555	response to interleukin-1	2.827455e-4
GO:0002906	negative regulation of mature B cell apoptosis	2.834534e-4
GO:0006310	DNA recombination	2.848285e-4
GO:0045626	negative regulation of T-helper 1 cell differentiation	2.850733e-4
GO:0090238	positive regulation of arachidonic acid secretion	2.850733e-4
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	2.850733e-4
GO:0032496	response to lipopolysaccharide	2.875552e-4
GO:0046879	hormone secretion	2.877808e-4
GO:0007162	negative regulation of cell adhesion	2.987527e-4
GO:0006695	cholesterol biosynthetic process	2.987873e-4
GO:0010985	negative regulation of lipoprotein particle clearance	3.086945e-4
GO:0034505	tooth mineralization	3.109596e-4
GO:0033153	T cell receptor V(D)J recombination	3.180930e-4
GO:0046626	regulation of insulin receptor signaling pathway	3.186851e-4
GO:0032224	positive regulation of synaptic transmission, cholinergic	3.228707e-4
GO:0048583	regulation of response to stimulus	3.238460e-4
GO:0033033	negative regulation of myeloid cell apoptosis	3.327195e-4
GO:0043032	positive regulation of macrophage activation	3.372423e-4
GO:0072091	regulation of stem cell proliferation	3.399202e-4
GO:0043303	mast cell degranulation	3.416681e-4
GO:0051089	constitutive protein ectodomain proteolysis	3.420323e-4
GO:0010751	negative regulation of nitric oxide mediated signal transduction	3.510123e-4
GO:0010754	negative regulation of cGMP-mediated signaling	3.510123e-4
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	3.510123e-4
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.510123e-4
GO:0060932	His-Purkinje system cell differentiation	3.546086e-4
GO:0060926	pacemaker cell development	3.546086e-4
GO:0060011	Sertoli cell proliferation	3.635166e-4
GO:0035815	positive regulation of renal sodium excretion	3.636553e-4
GO:0048284	organelle fusion	3.655753e-4
GO:0010873	positive regulation of cholesterol esterification	3.666223e-4
GO:0048340	paraxial mesoderm morphogenesis	3.688420e-4
GO:0002690	positive regulation of leukocyte chemotaxis	3.736312e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.783633e-4
GO:0060341	regulation of cellular localization	3.880191e-4
GO:0030046	parallel actin filament bundle assembly	3.902575e-4
GO:0010996	response to auditory stimulus	3.906959e-4
GO:0090168	Golgi reassembly	3.906959e-4
GO:0010896	regulation of triglyceride catabolic process	3.945198e-4
GO:0050851	antigen receptor-mediated signaling pathway	3.977196e-4
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	4.019358e-4
GO:0051952	regulation of amine transport	4.069430e-4
GO:0032959	inositol trisphosphate biosynthetic process	4.216219e-4
GO:0048520	positive regulation of behavior	4.322373e-4
GO:0044058	regulation of digestive system process	4.328660e-4
GO:0033032	regulation of myeloid cell apoptosis	4.355295e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	4.430403e-4
GO:0032880	regulation of protein localization	4.461805e-4
GO:0051412	response to corticosterone stimulus	4.525796e-4
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	4.591226e-4
GO:0071230	cellular response to amino acid stimulus	4.616621e-4
GO:0006578	betaine biosynthetic process	4.632641e-4
GO:0060124	positive regulation of growth hormone secretion	4.707844e-4
GO:0051051	negative regulation of transport	4.737765e-4
GO:0010159	specification of organ position	4.819470e-4
GO:0034377	plasma lipoprotein particle assembly	4.822790e-4
GO:0006507	GPI anchor release	5.119738e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	5.119738e-4
GO:0002830	positive regulation of type 2 immune response	5.208418e-4
GO:0032692	negative regulation of interleukin-1 production	5.288841e-4
GO:0008634	negative regulation of survival gene product expression	5.344451e-4
GO:0061041	regulation of wound healing	5.415980e-4
GO:0070201	regulation of establishment of protein localization	5.435065e-4
GO:0002443	leukocyte mediated immunity	5.498168e-4
GO:0032890	regulation of organic acid transport	5.530264e-4
GO:0034381	plasma lipoprotein particle clearance	5.552932e-4
GO:0046884	follicle-stimulating hormone secretion	5.562936e-4
GO:0032275	luteinizing hormone secretion	5.562936e-4
GO:0042098	T cell proliferation	5.597333e-4
GO:0019233	sensory perception of pain	5.715318e-4
GO:0030155	regulation of cell adhesion	5.719258e-4
GO:0050995	negative regulation of lipid catabolic process	5.727098e-4
GO:0008595	anterior/posterior axis specification, embryo	5.727098e-4
GO:0050818	regulation of coagulation	5.878826e-4
GO:0045039	protein import into mitochondrial inner membrane	5.880165e-4
GO:0006334	nucleosome assembly	5.899657e-4
GO:2000648	positive regulation of stem cell proliferation	5.961802e-4
GO:0002685	regulation of leukocyte migration	5.983023e-4
GO:0010749	regulation of nitric oxide mediated signal transduction	6.068088e-4
GO:0050710	negative regulation of cytokine secretion	6.098626e-4
GO:0009620	response to fungus	6.393423e-4
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	6.394788e-4
GO:0042044	fluid transport	6.464364e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	6.605271e-4
GO:0046503	glycerolipid catabolic process	6.631521e-4
GO:0031349	positive regulation of defense response	6.656385e-4
GO:0009651	response to salt stress	6.670887e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	6.684210e-4
GO:0010872	regulation of cholesterol esterification	6.783080e-4
GO:0019433	triglyceride catabolic process	6.799713e-4
GO:0001837	epithelial to mesenchymal transition	6.827058e-4
GO:0042108	positive regulation of cytokine biosynthetic process	6.874833e-4
GO:0043299	leukocyte degranulation	6.925482e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.080546e-4
GO:0044092	negative regulation of molecular function	7.198729e-4
GO:0031056	regulation of histone modification	7.225424e-4
GO:0016042	lipid catabolic process	7.225817e-4
GO:0043306	positive regulation of mast cell degranulation	7.266251e-4
GO:0009303	rRNA transcription	7.484833e-4
GO:0043066	negative regulation of apoptosis	7.489521e-4
GO:0001756	somitogenesis	7.763890e-4
GO:0035279	mRNA cleavage involved in gene silencing by miRNA	7.774933e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	7.814891e-4
GO:0007596	blood coagulation	7.837122e-4
GO:2000107	negative regulation of leukocyte apoptosis	7.851357e-4
GO:0006686	sphingomyelin biosynthetic process	7.912284e-4
GO:0010820	positive regulation of T cell chemotaxis	7.914232e-4
GO:0002250	adaptive immune response	8.164484e-4
GO:0015858	nucleoside transport	8.189497e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	8.189497e-4
GO:0006944	cellular membrane fusion	8.239342e-4
GO:0051049	regulation of transport	8.320082e-4
GO:0060548	negative regulation of cell death	8.333124e-4
GO:0007089	traversing start control point of mitotic cell cycle	8.476967e-4
GO:0002444	myeloid leukocyte mediated immunity	8.547077e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	8.572817e-4
GO:0071363	cellular response to growth factor stimulus	8.582914e-4
GO:0009789	positive regulation of abscisic acid mediated signaling pathway	8.779245e-4
GO:0051385	response to mineralocorticoid stimulus	8.837736e-4
GO:0030261	chromosome condensation	8.844486e-4
GO:0022409	positive regulation of cell-cell adhesion	8.902941e-4
GO:0042117	monocyte activation	9.081778e-4
GO:2000406	positive regulation of T cell migration	9.109027e-4
GO:0010745	negative regulation of macrophage derived foam cell differentiation	9.127435e-4
GO:0045136	development of secondary sexual characteristics	9.133375e-4
GO:0034197	triglyceride transport	9.400722e-4
GO:0051977	lysophospholipid transport	9.400722e-4
GO:0016320	endoplasmic reticulum membrane fusion	9.400722e-4
GO:0019858	cytosine metabolic process	9.400722e-4
GO:0007597	blood coagulation, intrinsic pathway	9.400722e-4
GO:0050434	positive regulation of viral transcription	9.551774e-4
GO:0021766	hippocampus development	9.821946e-4
GO:0042696	menarche	9.879728e-4
GO:0031440	regulation of mRNA 3'-end processing	1.004211e-3
GO:0030193	regulation of blood coagulation	1.014794e-3
GO:0043434	response to peptide hormone stimulus	1.015464e-3
GO:0030279	negative regulation of ossification	1.017542e-3
GO:0007599	hemostasis	1.020820e-3
GO:2000401	regulation of lymphocyte migration	1.022465e-3
GO:0090207	regulation of triglyceride metabolic process	1.023845e-3
GO:0043535	regulation of blood vessel endothelial cell migration	1.028200e-3
GO:0090277	positive regulation of peptide hormone secretion	1.035042e-3
GO:0051130	positive regulation of cellular component organization	1.041482e-3
GO:0031103	axon regeneration	1.066945e-3
GO:0008354	germ cell migration	1.083989e-3
GO:0051588	regulation of neurotransmitter transport	1.084156e-3
GO:0009914	hormone transport	1.086854e-3
GO:0035588	G-protein coupled purinergic receptor signaling pathway	1.087463e-3
GO:0006704	glucocorticoid biosynthetic process	1.092250e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	1.093268e-3
GO:0032856	activation of Ras GTPase activity	1.116241e-3
GO:0071286	cellular response to magnesium ion	1.127411e-3
GO:0001974	blood vessel remodeling	1.136436e-3
GO:0010817	regulation of hormone levels	1.138376e-3
GO:0050927	positive regulation of positive chemotaxis	1.139922e-3
GO:0048771	tissue remodeling	1.144404e-3
GO:0002532	production of molecular mediator involved in inflammatory response	1.176812e-3
GO:0051048	negative regulation of secretion	1.193192e-3
GO:0046546	development of primary male sexual characteristics	1.200670e-3
GO:0071229	cellular response to acid	1.202052e-3
GO:0010646	regulation of cell communication	1.202105e-3
GO:0060911	cardiac cell fate commitment	1.205113e-3
GO:0010984	regulation of lipoprotein particle clearance	1.205352e-3
GO:0010717	regulation of epithelial to mesenchymal transition	1.215840e-3
GO:0071219	cellular response to molecule of bacterial origin	1.219672e-3
GO:0034605	cellular response to heat	1.230837e-3
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	1.260976e-3
GO:0043270	positive regulation of ion transport	1.263627e-3
GO:0051066	dihydrobiopterin metabolic process	1.267304e-3
GO:0042697	menopause	1.267304e-3
GO:0043652	engulfment of apoptotic cell	1.272989e-3
GO:0032024	positive regulation of insulin secretion	1.301692e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.318118e-3
GO:0006656	phosphatidylcholine biosynthetic process	1.330709e-3
GO:0070206	protein trimerization	1.337319e-3
GO:0061025	membrane fusion	1.337909e-3
GO:0032488	Cdc42 protein signal transduction	1.338038e-3
GO:0002688	regulation of leukocyte chemotaxis	1.351226e-3
GO:0048339	paraxial mesoderm development	1.354455e-3
GO:0040012	regulation of locomotion	1.376136e-3
GO:0042136	neurotransmitter biosynthetic process	1.383033e-3
GO:0031507	heterochromatin formation	1.388670e-3
GO:0002224	toll-like receptor signaling pathway	1.388670e-3
GO:0060343	trabecula formation	1.471137e-3
GO:0035335	peptidyl-tyrosine dephosphorylation	1.476765e-3
GO:2000145	regulation of cell motility	1.493310e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.530576e-3
GO:0001812	positive regulation of type I hypersensitivity	1.530576e-3
GO:0050878	regulation of body fluid levels	1.538832e-3
GO:0042992	negative regulation of transcription factor import into nucleus	1.548887e-3
GO:0009266	response to temperature stimulus	1.572188e-3
GO:0043302	positive regulation of leukocyte degranulation	1.589127e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	1.598884e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	1.625213e-3
GO:0071622	regulation of granulocyte chemotaxis	1.636534e-3
GO:0031275	regulation of lateral pseudopodium assembly	1.643236e-3
GO:0042335	cuticle development	1.643236e-3
GO:0007612	learning	1.667620e-3
GO:0021759	globus pallidus development	1.703543e-3
GO:0060174	limb bud formation	1.729790e-3
GO:0002793	positive regulation of peptide secretion	1.752000e-3
GO:0023051	regulation of signaling	1.761831e-3
GO:0050729	positive regulation of inflammatory response	1.778087e-3
GO:0065005	protein-lipid complex assembly	1.792057e-3
GO:0031663	lipopolysaccharide-mediated signaling pathway	1.827168e-3
GO:0006611	protein export from nucleus	1.827168e-3
GO:0030223	neutrophil differentiation	1.835408e-3
GO:0010594	regulation of endothelial cell migration	1.845683e-3
GO:0050807	regulation of synapse organization	1.868033e-3
GO:0071222	cellular response to lipopolysaccharide	1.879501e-3
GO:0034728	nucleosome organization	1.962981e-3
GO:0006919	activation of caspase activity	1.998610e-3
GO:0061053	somite development	1.998991e-3
GO:0050926	regulation of positive chemotaxis	2.007232e-3
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	2.023856e-3
GO:0009743	response to carbohydrate stimulus	2.023981e-3
GO:0051223	regulation of protein transport	2.027972e-3
GO:0007126	meiosis	2.081606e-3
GO:0006054	N-acetylneuraminate metabolic process	2.085450e-3
GO:0019230	proprioception	2.097816e-3
GO:0031642	negative regulation of myelination	2.103672e-3
GO:0001947	heart looping	2.107727e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	2.113359e-3
GO:0002553	histamine secretion by mast cell	2.114637e-3
GO:0032696	negative regulation of interleukin-13 production	2.122673e-3
GO:0006833	water transport	2.135929e-3
GO:0001957	intramembranous ossification	2.147809e-3
GO:0010743	regulation of macrophage derived foam cell differentiation	2.147837e-3
GO:0050795	regulation of behavior	2.160395e-3
GO:0045807	positive regulation of endocytosis	2.162191e-3
GO:0020028	hemoglobin import	2.194374e-3
GO:0001956	positive regulation of neurotransmitter secretion	2.194374e-3
GO:0033327	Leydig cell differentiation	2.203586e-3
GO:0019637	organophosphate metabolic process	2.207515e-3
GO:0072560	type B pancreatic cell maturation	2.208382e-3
GO:0035106	operant conditioning	2.208382e-3
GO:0016266	O-glycan processing	2.208382e-3
GO:0045922	negative regulation of fatty acid metabolic process	2.262515e-3
GO:0031581	hemidesmosome assembly	2.273429e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	2.380704e-3
GO:0032731	positive regulation of interleukin-1 beta production	2.380704e-3
GO:0010955	negative regulation of protein processing	2.381741e-3
GO:2000772	regulation of cellular senescence	2.383025e-3
GO:0060596	mammary placode formation	2.397754e-3
GO:0016064	immunoglobulin mediated immune response	2.404099e-3
GO:0000187	activation of MAPK activity	2.408492e-3
GO:0001568	blood vessel development	2.410807e-3
GO:0014033	neural crest cell differentiation	2.449356e-3
GO:0006644	phospholipid metabolic process	2.450922e-3
GO:0042304	regulation of fatty acid biosynthetic process	2.456900e-3
GO:0061383	trabecula morphogenesis	2.457690e-3
GO:0030500	regulation of bone mineralization	2.458116e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	2.471058e-3
GO:0050803	regulation of synapse structure and activity	2.472068e-3
GO:0001944	vasculature development	2.487363e-3
GO:2001021	negative regulation of response to DNA damage stimulus	2.608582e-3
GO:0061153	trachea gland development	2.610260e-3
GO:0002791	regulation of peptide secretion	2.621968e-3
GO:0031347	regulation of defense response	2.625123e-3
GO:0032747	positive regulation of interleukin-23 production	2.646628e-3
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.652132e-3
GO:0010810	regulation of cell-substrate adhesion	2.662856e-3
GO:0050764	regulation of phagocytosis	2.694429e-3
GO:0043067	regulation of programmed cell death	2.716453e-3