Novel motif:143

name:	motif143_ATGATGTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032501	multicellular organismal process	2.876092e-23
GO:0050896	response to stimulus	3.975646e-23
GO:0050789	regulation of biological process	2.159674e-19
GO:0042221	response to chemical stimulus	2.165156e-18
GO:0065007	biological regulation	4.155481e-18
GO:0050794	regulation of cellular process	1.494410e-17
GO:0051716	cellular response to stimulus	2.079776e-17
GO:0007275	multicellular organismal development	7.409129e-17
GO:0050865	regulation of cell activation	4.207312e-16
GO:0032502	developmental process	2.094840e-15
GO:0048731	system development	1.256657e-14
GO:0007154	cell communication	1.601093e-14
GO:0048583	regulation of response to stimulus	2.221031e-14
GO:0015705	iodide transport	3.718639e-14
GO:0002694	regulation of leukocyte activation	5.537037e-14
GO:0048856	anatomical structure development	6.134219e-14
GO:0023052	signaling	5.570241e-13
GO:0051128	regulation of cellular component organization	6.278652e-13
GO:0032663	regulation of interleukin-2 production	6.510512e-13
GO:0051249	regulation of lymphocyte activation	7.849766e-13
GO:0023051	regulation of signaling	1.019053e-12
GO:0007165	signal transduction	1.582444e-12
GO:0065009	regulation of molecular function	3.530799e-12
GO:0006955	immune response	6.624077e-12
GO:0044281	small molecule metabolic process	1.189764e-11
GO:0051179	localization	1.370995e-11
GO:0002376	immune system process	1.525670e-11
GO:0050867	positive regulation of cell activation	1.679824e-11
GO:0048513	organ development	2.020357e-11
GO:0050863	regulation of T cell activation	2.133580e-11
GO:0051239	regulation of multicellular organismal process	4.866241e-11
GO:0065008	regulation of biological quality	5.548194e-11
GO:0010646	regulation of cell communication	5.605500e-11
GO:2000026	regulation of multicellular organismal development	6.968329e-11
GO:0050793	regulation of developmental process	1.464687e-10
GO:0006590	thyroid hormone generation	2.258646e-10
GO:0009966	regulation of signal transduction	2.357910e-10
GO:0045056	transcytosis	5.592783e-10
GO:0002696	positive regulation of leukocyte activation	6.003549e-10
GO:0006915	apoptosis	7.253216e-10
GO:0031641	regulation of myelination	1.184937e-9
GO:0012502	induction of programmed cell death	1.292653e-9
GO:0048518	positive regulation of biological process	1.484513e-9
GO:0006950	response to stress	1.647307e-9
GO:0012501	programmed cell death	1.867604e-9
GO:0007166	cell surface receptor linked signaling pathway	2.179594e-9
GO:0048522	positive regulation of cellular process	2.262487e-9
GO:0002682	regulation of immune system process	2.998554e-9
GO:0006917	induction of apoptosis	3.025782e-9
GO:0042445	hormone metabolic process	3.596517e-9
GO:0051960	regulation of nervous system development	4.443498e-9
GO:0042127	regulation of cell proliferation	5.892697e-9
GO:0006820	anion transport	6.295938e-9
GO:0006911	phagocytosis, engulfment	6.602887e-9
GO:0050790	regulation of catalytic activity	7.339973e-9
GO:0051336	regulation of hydrolase activity	7.367952e-9
GO:0008285	negative regulation of cell proliferation	7.690325e-9
GO:0051704	multi-organism process	7.887940e-9
GO:0032653	regulation of interleukin-10 production	8.312503e-9
GO:0042403	thyroid hormone metabolic process	9.164499e-9
GO:0048584	positive regulation of response to stimulus	1.284740e-8
GO:0002831	regulation of response to biotic stimulus	1.303865e-8
GO:0006508	proteolysis	1.411546e-8
GO:0050869	negative regulation of B cell activation	1.442505e-8
GO:0007608	sensory perception of smell	1.572649e-8
GO:0001817	regulation of cytokine production	1.693995e-8
GO:0050870	positive regulation of T cell activation	1.725666e-8
GO:0002676	regulation of chronic inflammatory response	1.774335e-8
GO:0010677	negative regulation of cellular carbohydrate metabolic process	1.848729e-8
GO:0043067	regulation of programmed cell death	2.130650e-8
GO:0016042	lipid catabolic process	2.145329e-8
GO:0006575	cellular modified amino acid metabolic process	2.159093e-8
GO:0051234	establishment of localization	2.939088e-8
GO:0007606	sensory perception of chemical stimulus	2.949884e-8
GO:0001775	cell activation	2.973999e-8
GO:0030168	platelet activation	3.506689e-8
GO:0042981	regulation of apoptosis	3.552520e-8
GO:0030836	positive regulation of actin filament depolymerization	3.619577e-8
GO:0021695	cerebellar cortex development	4.352021e-8
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.460372e-8
GO:0044057	regulation of system process	4.882814e-8
GO:0042102	positive regulation of T cell proliferation	5.105840e-8
GO:0008202	steroid metabolic process	5.905210e-8
GO:0010817	regulation of hormone levels	6.687685e-8
GO:0006810	transport	6.746207e-8
GO:0008152	metabolic process	6.786136e-8
GO:0006897	endocytosis	7.169694e-8
GO:0042129	regulation of T cell proliferation	8.914431e-8
GO:0007399	nervous system development	9.011464e-8
GO:0045727	positive regulation of translation	9.070753e-8
GO:0023057	negative regulation of signaling	9.306732e-8
GO:0051246	regulation of protein metabolic process	9.982884e-8
GO:0010648	negative regulation of cell communication	1.006441e-7
GO:0007618	mating	1.081068e-7
GO:0021681	cerebellar granular layer development	1.089013e-7
GO:0051247	positive regulation of protein metabolic process	1.099073e-7
GO:0043243	positive regulation of protein complex disassembly	1.099425e-7
GO:0007155	cell adhesion	1.105886e-7
GO:0023056	positive regulation of signaling	1.114082e-7
GO:0006952	defense response	1.121747e-7
GO:0006066	alcohol metabolic process	1.127480e-7
GO:0009987	cellular process	1.130308e-7
GO:0016192	vesicle-mediated transport	1.358563e-7
GO:0002684	positive regulation of immune system process	1.361513e-7
GO:0008219	cell death	1.534977e-7
GO:0010647	positive regulation of cell communication	1.632580e-7
GO:0009056	catabolic process	1.803362e-7
GO:0051969	regulation of transmission of nerve impulse	1.804063e-7
GO:0030509	BMP signaling pathway	1.907569e-7
GO:0051251	positive regulation of lymphocyte activation	2.095552e-7
GO:0061024	membrane organization	2.151095e-7
GO:0048585	negative regulation of response to stimulus	2.200834e-7
GO:0030154	cell differentiation	2.295413e-7
GO:0071896	protein localization to adherens junction	2.706871e-7
GO:0009968	negative regulation of signal transduction	2.707747e-7
GO:0048468	cell development	2.780146e-7
GO:0048699	generation of neurons	3.207918e-7
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.333163e-7
GO:0016265	death	3.435995e-7
GO:0032400	melanosome localization	3.460013e-7
GO:0051240	positive regulation of multicellular organismal process	3.463168e-7
GO:0016044	cellular membrane organization	3.868813e-7
GO:0032673	regulation of interleukin-4 production	4.034156e-7
GO:2000345	regulation of hepatocyte proliferation	4.164776e-7
GO:0044106	cellular amine metabolic process	4.319369e-7
GO:0010941	regulation of cell death	4.319660e-7
GO:0048519	negative regulation of biological process	4.506823e-7
GO:0048869	cellular developmental process	4.727983e-7
GO:0021683	cerebellar granular layer morphogenesis	5.370952e-7
GO:0021758	putamen development	5.505156e-7
GO:0021757	caudate nucleus development	5.505156e-7
GO:0006922	cleavage of lamin	5.505156e-7
GO:0022008	neurogenesis	5.724072e-7
GO:0043068	positive regulation of programmed cell death	5.801412e-7
GO:0018958	phenol-containing compound metabolic process	5.856680e-7
GO:0034122	negative regulation of toll-like receptor signaling pathway	6.569708e-7
GO:0010033	response to organic substance	6.715926e-7
GO:0051875	pigment granule localization	6.732091e-7
GO:0009308	amine metabolic process	7.009564e-7
GO:0040011	locomotion	7.015678e-7
GO:0045619	regulation of lymphocyte differentiation	8.259656e-7
GO:0046034	ATP metabolic process	8.464864e-7
GO:0048523	negative regulation of cellular process	9.160294e-7
GO:0009611	response to wounding	9.299626e-7
GO:0019222	regulation of metabolic process	9.651455e-7
GO:0002769	natural killer cell inhibitory signaling pathway	1.078372e-6
GO:0018904	organic ether metabolic process	1.118226e-6
GO:0001818	negative regulation of cytokine production	1.132277e-6
GO:0021549	cerebellum development	1.170735e-6
GO:0050671	positive regulation of lymphocyte proliferation	1.220052e-6
GO:0050769	positive regulation of neurogenesis	1.239823e-6
GO:0042180	cellular ketone metabolic process	1.276690e-6
GO:0015698	inorganic anion transport	1.373670e-6
GO:0009628	response to abiotic stimulus	1.391181e-6
GO:0070663	regulation of leukocyte proliferation	1.414865e-6
GO:0019538	protein metabolic process	1.425675e-6
GO:0051640	organelle localization	1.427508e-6
GO:0006629	lipid metabolic process	1.562126e-6
GO:0051130	positive regulation of cellular component organization	1.572075e-6
GO:0043065	positive regulation of apoptosis	1.749808e-6
GO:0032733	positive regulation of interleukin-10 production	1.852650e-6
GO:0007320	insemination	1.951559e-6
GO:0050954	sensory perception of mechanical stimulus	2.002021e-6
GO:0071285	cellular response to lithium ion	2.036874e-6
GO:0050830	defense response to Gram-positive bacterium	2.133546e-6
GO:0006725	cellular aromatic compound metabolic process	2.139298e-6
GO:0042325	regulation of phosphorylation	2.238182e-6
GO:0032891	negative regulation of organic acid transport	2.308073e-6
GO:0006928	cellular component movement	2.383553e-6
GO:0006520	cellular amino acid metabolic process	2.384014e-6
GO:0044093	positive regulation of molecular function	2.413936e-6
GO:0009593	detection of chemical stimulus	2.633773e-6
GO:0045580	regulation of T cell differentiation	2.829177e-6
GO:0045595	regulation of cell differentiation	2.933016e-6
GO:0032743	positive regulation of interleukin-2 production	2.972213e-6
GO:0016043	cellular component organization	3.016387e-6
GO:0032268	regulation of cellular protein metabolic process	3.024136e-6
GO:0009967	positive regulation of signal transduction	3.242613e-6
GO:0021756	striatum development	3.295861e-6
GO:0032680	regulation of tumor necrosis factor production	3.365264e-6
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	3.394224e-6
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.485220e-6
GO:0002678	positive regulation of chronic inflammatory response	3.642825e-6
GO:0032844	regulation of homeostatic process	3.652457e-6
GO:0030182	neuron differentiation	3.717917e-6
GO:0009653	anatomical structure morphogenesis	3.838120e-6
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	3.890887e-6
GO:0045664	regulation of neuron differentiation	3.997894e-6
GO:0048732	gland development	4.076357e-6
GO:0032946	positive regulation of mononuclear cell proliferation	4.086408e-6
GO:0046503	glycerolipid catabolic process	4.135648e-6
GO:0007605	sensory perception of sound	4.188400e-6
GO:0030510	regulation of BMP signaling pathway	4.321730e-6
GO:0007088	regulation of mitosis	4.433290e-6
GO:0007015	actin filament organization	4.447816e-6
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	4.462235e-6
GO:0042537	benzene-containing compound metabolic process	4.851704e-6
GO:0045069	regulation of viral genome replication	4.889336e-6
GO:0010866	regulation of triglyceride biosynthetic process	4.922669e-6
GO:0019220	regulation of phosphate metabolic process	5.203846e-6
GO:0044248	cellular catabolic process	5.213628e-6
GO:0022414	reproductive process	5.225324e-6
GO:0043900	regulation of multi-organism process	5.353554e-6
GO:0019752	carboxylic acid metabolic process	5.386104e-6
GO:0009893	positive regulation of metabolic process	5.708320e-6
GO:0051345	positive regulation of hydrolase activity	6.291079e-6
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	6.327421e-6
GO:0031644	regulation of neurological system process	6.334599e-6
GO:0060284	regulation of cell development	6.689174e-6
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	6.698726e-6
GO:0050767	regulation of neurogenesis	7.206242e-6
GO:0032101	regulation of response to external stimulus	7.396408e-6
GO:0051726	regulation of cell cycle	7.665470e-6
GO:0046464	acylglycerol catabolic process	7.906835e-6
GO:0007599	hemostasis	7.935536e-6
GO:0033363	secretory granule organization	7.954481e-6
GO:0031399	regulation of protein modification process	8.043507e-6
GO:0006662	glycerol ether metabolic process	8.407972e-6
GO:0043255	regulation of carbohydrate biosynthetic process	8.439617e-6
GO:0021528	commissural neuron differentiation in spinal cord	8.456817e-6
GO:0010942	positive regulation of cell death	8.693348e-6
GO:0032536	regulation of cell projection size	8.795704e-6
GO:0000003	reproduction	8.867914e-6
GO:0080134	regulation of response to stress	8.895320e-6
GO:0009605	response to external stimulus	9.036312e-6
GO:0006811	ion transport	9.371486e-6
GO:0071840	cellular component organization or biogenesis	9.478373e-6
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	9.605093e-6
GO:0032649	regulation of interferon-gamma production	9.636621e-6
GO:0002683	negative regulation of immune system process	9.655223e-6
GO:0010557	positive regulation of macromolecule biosynthetic process	1.023000e-5
GO:0070665	positive regulation of leukocyte proliferation	1.042142e-5
GO:0034143	regulation of toll-like receptor 4 signaling pathway	1.085475e-5
GO:0031328	positive regulation of cellular biosynthetic process	1.085669e-5
GO:0051956	negative regulation of amino acid transport	1.094234e-5
GO:0006448	regulation of translational elongation	1.094234e-5
GO:0061031	endodermal digestive tract morphogenesis	1.122004e-5
GO:0019836	hemolysis by symbiont of host erythrocytes	1.130944e-5
GO:0010757	negative regulation of plasminogen activation	1.155281e-5
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1.168171e-5
GO:0050670	regulation of lymphocyte proliferation	1.203101e-5
GO:0001932	regulation of protein phosphorylation	1.230361e-5
GO:0007596	blood coagulation	1.243195e-5
GO:0003006	developmental process involved in reproduction	1.253027e-5
GO:0045786	negative regulation of cell cycle	1.303841e-5
GO:0010769	regulation of cell morphogenesis involved in differentiation	1.317674e-5
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.339884e-5
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1.354397e-5
GO:0030574	collagen catabolic process	1.364557e-5
GO:0031325	positive regulation of cellular metabolic process	1.387914e-5
GO:0010035	response to inorganic substance	1.444997e-5
GO:0031323	regulation of cellular metabolic process	1.450616e-5
GO:0051606	detection of stimulus	1.485181e-5
GO:0051707	response to other organism	1.550325e-5
GO:0051648	vesicle localization	1.584442e-5
GO:0006082	organic acid metabolic process	1.635262e-5
GO:0010720	positive regulation of cell development	1.650153e-5
GO:0006109	regulation of carbohydrate metabolic process	1.668289e-5
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.677137e-5
GO:0007620	copulation	1.708031e-5
GO:0009891	positive regulation of biosynthetic process	1.714969e-5
GO:0007638	mechanosensory behavior	1.835097e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.873957e-5
GO:0010638	positive regulation of organelle organization	1.885931e-5
GO:0002037	negative regulation of L-glutamate transport	1.933099e-5
GO:0045994	positive regulation of translational initiation by iron	1.933099e-5
GO:0035871	protein K11-linked deubiquitination	2.057761e-5
GO:0051877	pigment granule aggregation in cell center	2.063060e-5
GO:0080090	regulation of primary metabolic process	2.077518e-5
GO:0009201	ribonucleoside triphosphate biosynthetic process	2.084824e-5
GO:0044243	multicellular organismal catabolic process	2.139822e-5
GO:0060740	prostate gland epithelium morphogenesis	2.251172e-5
GO:0022604	regulation of cell morphogenesis	2.275033e-5
GO:0060512	prostate gland morphogenesis	2.293755e-5
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	2.346607e-5
GO:0006417	regulation of translation	2.350286e-5
GO:0035094	response to nicotine	2.467265e-5
GO:0052547	regulation of peptidase activity	2.533540e-5
GO:0044238	primary metabolic process	2.539395e-5
GO:0045076	regulation of interleukin-2 biosynthetic process	2.539696e-5
GO:0008624	induction of apoptosis by extracellular signals	2.583243e-5
GO:0048608	reproductive structure development	2.615259e-5
GO:0010675	regulation of cellular carbohydrate metabolic process	2.625018e-5
GO:0050852	T cell receptor signaling pathway	2.663035e-5
GO:0009617	response to bacterium	2.744281e-5
GO:0046032	ADP catabolic process	2.876897e-5
GO:0046709	IDP catabolic process	2.876897e-5
GO:0042060	wound healing	2.883536e-5
GO:0022603	regulation of anatomical structure morphogenesis	2.941625e-5
GO:0070670	response to interleukin-4	2.971515e-5
GO:0032944	regulation of mononuclear cell proliferation	3.022707e-5
GO:0030878	thyroid gland development	3.165855e-5
GO:0009268	response to pH	3.170399e-5
GO:0010608	posttranscriptional regulation of gene expression	3.195055e-5
GO:0033135	regulation of peptidyl-serine phosphorylation	3.297258e-5
GO:0031214	biomineral tissue development	3.322467e-5
GO:2000021	regulation of ion homeostasis	3.340515e-5
GO:0031223	auditory behavior	3.369532e-5
GO:0009607	response to biotic stimulus	3.434546e-5
GO:0032713	negative regulation of interleukin-4 production	3.556525e-5
GO:0051574	positive regulation of histone H3-K9 methylation	3.661798e-5
GO:0044092	negative regulation of molecular function	3.677324e-5
GO:0090207	regulation of triglyceride metabolic process	3.687948e-5
GO:2000116	regulation of cysteine-type endopeptidase activity	3.704225e-5
GO:0045597	positive regulation of cell differentiation	3.860373e-5
GO:0008207	C21-steroid hormone metabolic process	3.893540e-5
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	3.927232e-5
GO:0019433	triglyceride catabolic process	3.933127e-5
GO:0044242	cellular lipid catabolic process	3.951656e-5
GO:0034612	response to tumor necrosis factor	3.961333e-5
GO:0032401	establishment of melanosome localization	4.030939e-5
GO:0010604	positive regulation of macromolecule metabolic process	4.095822e-5
GO:0050878	regulation of body fluid levels	4.153600e-5
GO:0055086	nucleobase-containing small molecule metabolic process	4.174432e-5
GO:0002819	regulation of adaptive immune response	4.199412e-5
GO:0010038	response to metal ion	4.220187e-5
GO:0071675	regulation of mononuclear cell migration	4.343743e-5
GO:0010755	regulation of plasminogen activation	4.379568e-5
GO:0008347	glial cell migration	4.447055e-5
GO:0048666	neuron development	4.517412e-5
GO:0032049	cardiolipin biosynthetic process	4.756705e-5
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	5.247710e-5
GO:0050849	negative regulation of calcium-mediated signaling	5.313446e-5
GO:0050776	regulation of immune response	5.327259e-5
GO:0032656	regulation of interleukin-13 production	5.339486e-5
GO:0032703	negative regulation of interleukin-2 production	5.346968e-5
GO:0002697	regulation of immune effector process	5.408529e-5
GO:0055088	lipid homeostasis	5.444691e-5
GO:0016119	carotene metabolic process	5.493140e-5
GO:0021544	subpallium development	5.541678e-5
GO:0002839	positive regulation of immune response to tumor cell	5.577169e-5
GO:0046637	regulation of alpha-beta T cell differentiation	5.729985e-5
GO:0002237	response to molecule of bacterial origin	5.749376e-5
GO:0003008	system process	5.922872e-5
GO:0010759	positive regulation of macrophage chemotaxis	5.963444e-5
GO:0051250	negative regulation of lymphocyte activation	6.003543e-5
GO:0048745	smooth muscle tissue development	6.011292e-5
GO:0043547	positive regulation of GTPase activity	6.254295e-5
GO:0002082	regulation of oxidative phosphorylation	6.295313e-5
GO:0044087	regulation of cellular component biogenesis	6.360660e-5
GO:0030513	positive regulation of BMP signaling pathway	6.498561e-5
GO:0030728	ovulation	6.502000e-5
GO:0009142	nucleoside triphosphate biosynthetic process	6.514365e-5
GO:2000352	negative regulation of endothelial cell apoptosis	6.617867e-5
GO:0010719	negative regulation of epithelial to mesenchymal transition	6.617867e-5
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	6.840590e-5
GO:0051905	establishment of pigment granule localization	6.853911e-5
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	6.861850e-5
GO:0051056	regulation of small GTPase mediated signal transduction	6.950599e-5
GO:0008050	female courtship behavior	7.038997e-5
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	7.038997e-5
GO:0043244	regulation of protein complex disassembly	7.138699e-5
GO:0060743	epithelial cell maturation involved in prostate gland development	7.157948e-5
GO:0032270	positive regulation of cellular protein metabolic process	7.249020e-5
GO:0045494	photoreceptor cell maintenance	7.727019e-5
GO:0021696	cerebellar cortex morphogenesis	7.731741e-5
GO:0034139	regulation of toll-like receptor 3 signaling pathway	7.760755e-5
GO:0006595	polyamine metabolic process	8.051023e-5
GO:0008284	positive regulation of cell proliferation	8.127844e-5
GO:0002576	platelet degranulation	8.173064e-5
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	8.301837e-5
GO:0007176	regulation of epidermal growth factor-activated receptor activity	8.471348e-5
GO:0022037	metencephalon development	8.497858e-5
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	8.758392e-5
GO:0050778	positive regulation of immune response	9.199076e-5
GO:0070560	protein secretion by platelet	9.238189e-5
GO:0060305	regulation of cell diameter	9.238189e-5
GO:0010920	negative regulation of inositol phosphate biosynthetic process	9.238189e-5
GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity	9.238189e-5
GO:0030845	inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway	9.238189e-5
GO:0009894	regulation of catabolic process	9.387215e-5
GO:0045621	positive regulation of lymphocyte differentiation	9.617979e-5
GO:0032496	response to lipopolysaccharide	9.696962e-5
GO:0033121	regulation of purine nucleotide catabolic process	9.960852e-5
GO:0042108	positive regulation of cytokine biosynthetic process	1.007225e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.022908e-4
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.023882e-4
GO:0034121	regulation of toll-like receptor signaling pathway	1.023882e-4
GO:0046007	negative regulation of activated T cell proliferation	1.042153e-4
GO:0010758	regulation of macrophage chemotaxis	1.042962e-4
GO:0030101	natural killer cell activation	1.052464e-4
GO:0002286	T cell activation involved in immune response	1.052464e-4
GO:0033036	macromolecule localization	1.058850e-4
GO:0071295	cellular response to vitamin	1.103239e-4
GO:0003166	bundle of His development	1.131878e-4
GO:0060741	prostate gland stromal morphogenesis	1.156421e-4
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	1.164082e-4
GO:0032233	positive regulation of actin filament bundle assembly	1.181707e-4
GO:0046634	regulation of alpha-beta T cell activation	1.184748e-4
GO:0070536	protein K63-linked deubiquitination	1.188020e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.206144e-4
GO:0060291	long-term synaptic potentiation	1.238043e-4
GO:0055067	monovalent inorganic cation homeostasis	1.259977e-4
GO:0046325	negative regulation of glucose import	1.263931e-4
GO:0032494	response to peptidoglycan	1.271818e-4
GO:0051495	positive regulation of cytoskeleton organization	1.274414e-4
GO:0009145	purine nucleoside triphosphate biosynthetic process	1.275105e-4
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	1.278276e-4
GO:0045123	cellular extravasation	1.283446e-4
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	1.283487e-4
GO:0002077	acrosome matrix dispersal	1.283487e-4
GO:0006447	regulation of translational initiation by iron	1.285031e-4
GO:0006754	ATP biosynthetic process	1.314184e-4
GO:0048711	positive regulation of astrocyte differentiation	1.325172e-4
GO:0021680	cerebellar Purkinje cell layer development	1.325172e-4
GO:0016125	sterol metabolic process	1.364936e-4
GO:0021707	cerebellar granule cell differentiation	1.367373e-4
GO:0071622	regulation of granulocyte chemotaxis	1.367687e-4
GO:0051656	establishment of organelle localization	1.378390e-4
GO:0045777	positive regulation of blood pressure	1.409152e-4
GO:0010529	negative regulation of transposition	1.438099e-4
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.449169e-4
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	1.472521e-4
GO:0042466	chemokinesis	1.472521e-4
GO:0045082	positive regulation of interleukin-10 biosynthetic process	1.520201e-4
GO:0048241	epinephrine transport	1.527063e-4
GO:0048011	nerve growth factor receptor signaling pathway	1.591163e-4
GO:2000347	positive regulation of hepatocyte proliferation	1.602705e-4
GO:0090291	negative regulation of osteoclast proliferation	1.602705e-4
GO:2000349	negative regulation of CD40 signaling pathway	1.602705e-4
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.602705e-4
GO:0072573	tolerance induction to lipopolysaccharide	1.602705e-4
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.602705e-4
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.602705e-4
GO:0022600	digestive system process	1.612843e-4
GO:0008625	induction of apoptosis via death domain receptors	1.630527e-4
GO:0000413	protein peptidyl-prolyl isomerization	1.638368e-4
GO:0048870	cell motility	1.644838e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	1.649277e-4
GO:0043046	DNA methylation involved in gamete generation	1.652781e-4
GO:0050882	voluntary musculoskeletal movement	1.653995e-4
GO:0021860	pyramidal neuron development	1.653995e-4
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.665547e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.680902e-4
GO:0045787	positive regulation of cell cycle	1.703369e-4
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.717240e-4
GO:0030644	cellular chloride ion homeostasis	1.719236e-4
GO:0006909	phagocytosis	1.767742e-4
GO:0001539	ciliary or flagellar motility	1.772780e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.795024e-4
GO:0034587	piRNA metabolic process	1.802008e-4
GO:0031670	cellular response to nutrient	1.837090e-4
GO:0042035	regulation of cytokine biosynthetic process	1.840791e-4
GO:0070887	cellular response to chemical stimulus	1.886321e-4
GO:0046635	positive regulation of alpha-beta T cell activation	1.886926e-4
GO:0007346	regulation of mitotic cell cycle	1.969221e-4
GO:0002064	epithelial cell development	1.980437e-4
GO:2000639	negative regulation of SREBP-mediated signaling pathway	1.994371e-4
GO:2000346	negative regulation of hepatocyte proliferation	1.994371e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.995919e-4
GO:0008203	cholesterol metabolic process	2.045736e-4
GO:0072334	UDP-galactose transmembrane transport	2.080257e-4
GO:0045161	neuronal ion channel clustering	2.110419e-4
GO:0090324	negative regulation of oxidative phosphorylation	2.119096e-4
GO:0010255	glucose mediated signaling pathway	2.119096e-4
GO:0010717	regulation of epithelial to mesenchymal transition	2.150238e-4
GO:0008206	bile acid metabolic process	2.162039e-4
GO:0070527	platelet aggregation	2.191704e-4
GO:0051798	positive regulation of hair follicle development	2.197643e-4
GO:0048167	regulation of synaptic plasticity	2.218707e-4
GO:0042446	hormone biosynthetic process	2.227515e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.237976e-4
GO:0007167	enzyme linked receptor protein signaling pathway	2.260459e-4
GO:0014047	glutamate secretion	2.272013e-4
GO:0030198	extracellular matrix organization	2.287585e-4
GO:0048667	cell morphogenesis involved in neuron differentiation	2.334505e-4
GO:0051971	positive regulation of transmission of nerve impulse	2.360516e-4
GO:0010466	negative regulation of peptidase activity	2.363463e-4
GO:0045900	negative regulation of translational elongation	2.435903e-4
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	2.448854e-4
GO:0006766	vitamin metabolic process	2.454656e-4
GO:0046887	positive regulation of hormone secretion	2.483844e-4
GO:0051346	negative regulation of hydrolase activity	2.505403e-4
GO:0010812	negative regulation of cell-substrate adhesion	2.510303e-4
GO:0006887	exocytosis	2.544108e-4
GO:0071299	cellular response to vitamin A	2.566826e-4
GO:0015949	nucleobase-containing small molecule interconversion	2.669456e-4
GO:0048589	developmental growth	2.673901e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	2.686743e-4
GO:0002793	positive regulation of peptide secretion	2.708139e-4
GO:0031060	regulation of histone methylation	2.711379e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	2.745724e-4
GO:0071300	cellular response to retinoic acid	2.751264e-4
GO:0002036	regulation of L-glutamate transport	2.784623e-4
GO:0001819	positive regulation of cytokine production	2.808680e-4
GO:0045071	negative regulation of viral genome replication	2.817870e-4
GO:0090277	positive regulation of peptide hormone secretion	2.912939e-4
GO:0055114	oxidation-reduction process	2.917455e-4
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	2.923181e-4
GO:0033043	regulation of organelle organization	2.949975e-4
GO:0035058	nonmotile primary cilium assembly	2.986843e-4
GO:0046851	negative regulation of bone remodeling	2.992354e-4
GO:0030030	cell projection organization	3.012120e-4
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.031828e-4
GO:0044236	multicellular organismal metabolic process	3.044720e-4
GO:0072358	cardiovascular system development	3.075018e-4
GO:0002765	immune response-inhibiting signal transduction	3.129023e-4
GO:0071356	cellular response to tumor necrosis factor	3.139200e-4
GO:0044271	cellular nitrogen compound biosynthetic process	3.170514e-4
GO:0061041	regulation of wound healing	3.213415e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	5.819917e-18
GO:0007154	cell communication	3.037573e-14
GO:0048583	regulation of response to stimulus	3.762877e-13
GO:0002673	regulation of acute inflammatory response	4.122581e-13
GO:0050870	positive regulation of T cell activation	7.315863e-13
GO:0016125	sterol metabolic process	1.814493e-12
GO:0016126	sterol biosynthetic process	1.919468e-12
GO:0051347	positive regulation of transferase activity	1.488039e-11
GO:0007165	signal transduction	2.075223e-11
GO:0008203	cholesterol metabolic process	4.212432e-11
GO:0032964	collagen biosynthetic process	5.784313e-11
GO:0023052	signaling	6.253042e-11
GO:0030199	collagen fibril organization	1.186250e-10
GO:0034505	tooth mineralization	1.264846e-10
GO:0006695	cholesterol biosynthetic process	1.616376e-10
GO:0033674	positive regulation of kinase activity	2.613338e-10
GO:0002920	regulation of humoral immune response	3.133848e-10
GO:0030036	actin cytoskeleton organization	3.254899e-10
GO:0006694	steroid biosynthetic process	3.263611e-10
GO:0045582	positive regulation of T cell differentiation	3.430843e-10
GO:0045860	positive regulation of protein kinase activity	3.581592e-10
GO:0019216	regulation of lipid metabolic process	5.751818e-10
GO:0051056	regulation of small GTPase mediated signal transduction	8.548613e-10
GO:0002922	positive regulation of humoral immune response	1.130282e-9
GO:0030029	actin filament-based process	1.402174e-9
GO:0032369	negative regulation of lipid transport	1.688000e-9
GO:0070613	regulation of protein processing	1.793931e-9
GO:0045621	positive regulation of lymphocyte differentiation	1.918432e-9
GO:0009966	regulation of signal transduction	2.073541e-9
GO:0051716	cellular response to stimulus	2.585615e-9
GO:0032375	negative regulation of cholesterol transport	2.718348e-9
GO:0002682	regulation of immune system process	3.359642e-9
GO:0002708	positive regulation of lymphocyte mediated immunity	3.982322e-9
GO:0050863	regulation of T cell activation	4.005814e-9
GO:0007155	cell adhesion	4.803320e-9
GO:0071229	cellular response to acid	5.302684e-9
GO:0071230	cellular response to amino acid stimulus	6.585905e-9
GO:0050776	regulation of immune response	6.617461e-9
GO:0031960	response to corticosteroid stimulus	8.383107e-9
GO:0050790	regulation of catalytic activity	8.578296e-9
GO:0002675	positive regulation of acute inflammatory response	8.958145e-9
GO:0022610	biological adhesion	9.036504e-9
GO:0000187	activation of MAPK activity	9.380111e-9
GO:0050727	regulation of inflammatory response	1.060431e-8
GO:0007010	cytoskeleton organization	1.340450e-8
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.396539e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.660891e-8
GO:0043085	positive regulation of catalytic activity	2.120547e-8
GO:0023051	regulation of signaling	2.974751e-8
GO:0010985	negative regulation of lipoprotein particle clearance	3.247269e-8
GO:0006707	cholesterol catabolic process	3.715685e-8
GO:0044093	positive regulation of molecular function	3.726185e-8
GO:0002685	regulation of leukocyte migration	4.452538e-8
GO:0045580	regulation of T cell differentiation	4.497181e-8
GO:0006952	defense response	5.030478e-8
GO:0051005	negative regulation of lipoprotein lipase activity	5.111506e-8
GO:0034382	chylomicron remnant clearance	5.111506e-8
GO:0031347	regulation of defense response	5.433359e-8
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	6.464124e-8
GO:0045859	regulation of protein kinase activity	8.441305e-8
GO:0002696	positive regulation of leukocyte activation	1.183198e-7
GO:0071418	cellular response to amine stimulus	1.208492e-7
GO:0001932	regulation of protein phosphorylation	1.219687e-7
GO:0051338	regulation of transferase activity	1.252406e-7
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	1.297771e-7
GO:0030449	regulation of complement activation	1.307010e-7
GO:0042221	response to chemical stimulus	1.377718e-7
GO:0019218	regulation of steroid metabolic process	1.493785e-7
GO:0031532	actin cytoskeleton reorganization	1.645881e-7
GO:0007015	actin filament organization	1.688047e-7
GO:0007166	cell surface receptor linked signaling pathway	1.991621e-7
GO:0050778	positive regulation of immune response	2.103205e-7
GO:0008202	steroid metabolic process	2.139790e-7
GO:0010984	regulation of lipoprotein particle clearance	2.246514e-7
GO:0071417	cellular response to organic nitrogen	2.253460e-7
GO:0045940	positive regulation of steroid metabolic process	2.411854e-7
GO:0043549	regulation of kinase activity	2.445246e-7
GO:0090209	negative regulation of triglyceride metabolic process	2.588783e-7
GO:0051240	positive regulation of multicellular organismal process	2.593239e-7
GO:0048261	negative regulation of receptor-mediated endocytosis	2.785006e-7
GO:0010954	positive regulation of protein processing	2.803132e-7
GO:0046890	regulation of lipid biosynthetic process	2.907588e-7
GO:0050995	negative regulation of lipid catabolic process	2.972212e-7
GO:0045717	negative regulation of fatty acid biosynthetic process	3.282647e-7
GO:0035023	regulation of Rho protein signal transduction	3.410424e-7
GO:0019098	reproductive behavior	3.788613e-7
GO:0001970	positive regulation of activation of membrane attack complex	3.802746e-7
GO:0060346	bone trabecula formation	3.918438e-7
GO:0045619	regulation of lymphocyte differentiation	4.215685e-7
GO:0050706	regulation of interleukin-1 beta secretion	4.306199e-7
GO:0050954	sensory perception of mechanical stimulus	4.357200e-7
GO:0042102	positive regulation of T cell proliferation	4.442020e-7
GO:0046314	phosphocreatine biosynthetic process	4.501777e-7
GO:0002684	positive regulation of immune system process	4.572344e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	4.714846e-7
GO:0010897	negative regulation of triglyceride catabolic process	4.714846e-7
GO:0045922	negative regulation of fatty acid metabolic process	5.078836e-7
GO:0050867	positive regulation of cell activation	5.143559e-7
GO:0032501	multicellular organismal process	5.371383e-7
GO:0051251	positive regulation of lymphocyte activation	5.945730e-7
GO:0071902	positive regulation of protein serine/threonine kinase activity	5.996045e-7
GO:0051094	positive regulation of developmental process	6.106430e-7
GO:0050821	protein stabilization	6.277598e-7
GO:0032078	negative regulation of endodeoxyribonuclease activity	6.785999e-7
GO:0006922	cleavage of lamin	6.785999e-7
GO:0007600	sensory perception	6.881679e-7
GO:0001967	suckling behavior	7.261733e-7
GO:0043406	positive regulation of MAP kinase activity	7.742039e-7
GO:0070208	protein heterotrimerization	7.909037e-7
GO:0016042	lipid catabolic process	8.448912e-7
GO:0022600	digestive system process	1.014502e-6
GO:0065009	regulation of molecular function	1.037830e-6
GO:0014075	response to amine stimulus	1.180566e-6
GO:0001957	intramembranous ossification	1.182840e-6
GO:0050810	regulation of steroid biosynthetic process	1.183021e-6
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.314769e-6
GO:0035094	response to nicotine	1.405610e-6
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	1.413486e-6
GO:0050704	regulation of interleukin-1 secretion	1.416801e-6
GO:0010033	response to organic substance	1.454219e-6
GO:0048856	anatomical structure development	1.458818e-6
GO:0001969	regulation of activation of membrane attack complex	1.479355e-6
GO:0007352	zygotic specification of dorsal/ventral axis	1.591250e-6
GO:0070508	cholesterol import	1.653697e-6
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.746173e-6
GO:0019220	regulation of phosphate metabolic process	1.865066e-6
GO:2000639	negative regulation of SREBP-mediated signaling pathway	1.883117e-6
GO:2000346	negative regulation of hepatocyte proliferation	1.883117e-6
GO:2000273	positive regulation of receptor activity	1.984156e-6
GO:0010749	regulation of nitric oxide mediated signal transduction	2.054629e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	2.054629e-6
GO:0002885	positive regulation of hypersensitivity	2.079574e-6
GO:0042325	regulation of phosphorylation	2.225656e-6
GO:0002861	regulation of inflammatory response to antigenic stimulus	2.234684e-6
GO:0032101	regulation of response to external stimulus	2.351800e-6
GO:0002694	regulation of leukocyte activation	2.368757e-6
GO:0045834	positive regulation of lipid metabolic process	2.419621e-6
GO:0050707	regulation of cytokine secretion	2.528470e-6
GO:0045597	positive regulation of cell differentiation	2.538496e-6
GO:0002821	positive regulation of adaptive immune response	2.593000e-6
GO:0048731	system development	2.598545e-6
GO:0032879	regulation of localization	2.909178e-6
GO:0002577	regulation of antigen processing and presentation	2.921335e-6
GO:0010893	positive regulation of steroid biosynthetic process	2.952077e-6
GO:0034441	plasma lipoprotein particle oxidation	2.959620e-6
GO:0032963	collagen metabolic process	3.027877e-6
GO:0043589	skin morphogenesis	3.081186e-6
GO:0045931	positive regulation of mitotic cell cycle	3.090004e-6
GO:0051336	regulation of hydrolase activity	3.183127e-6
GO:0046634	regulation of alpha-beta T cell activation	3.394061e-6
GO:0002688	regulation of leukocyte chemotaxis	3.413933e-6
GO:0007179	transforming growth factor beta receptor signaling pathway	3.549865e-6
GO:0006468	protein phosphorylation	3.555927e-6
GO:0031620	regulation of fever generation	3.558332e-6
GO:0031214	biomineral tissue development	3.658131e-6
GO:0051917	regulation of fibrinolysis	3.726340e-6
GO:0043200	response to amino acid stimulus	3.916497e-6
GO:0060558	regulation of calcidiol 1-monooxygenase activity	3.916971e-6
GO:0007605	sensory perception of sound	4.022999e-6
GO:0050865	regulation of cell activation	4.061317e-6
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	4.315086e-6
GO:0060192	negative regulation of lipase activity	4.669009e-6
GO:0046578	regulation of Ras protein signal transduction	4.737413e-6
GO:0061383	trabecula morphogenesis	4.969497e-6
GO:0048513	organ development	5.264061e-6
GO:0043652	engulfment of apoptotic cell	5.319043e-6
GO:0060557	positive regulation of vitamin D biosynthetic process	5.361744e-6
GO:0007275	multicellular organismal development	5.498853e-6
GO:0007176	regulation of epidermal growth factor-activated receptor activity	5.854813e-6
GO:0002687	positive regulation of leukocyte migration	5.924893e-6
GO:0042345	regulation of NF-kappaB import into nucleus	6.155514e-6
GO:0035272	exocrine system development	6.193272e-6
GO:0010754	negative regulation of cGMP-mediated signaling	6.441570e-6
GO:0030967	ER-nuclear sterol response pathway	6.441570e-6
GO:0010982	regulation of high-density lipoprotein particle clearance	6.441570e-6
GO:0010751	negative regulation of nitric oxide mediated signal transduction	6.441570e-6
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	6.441570e-6
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	6.441570e-6
GO:0035419	activation of MAPK activity involved in innate immune response	6.726430e-6
GO:0008588	release of cytoplasmic sequestered NF-kappaB	6.756227e-6
GO:0051384	response to glucocorticoid stimulus	6.871255e-6
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.566738e-6
GO:0048251	elastic fiber assembly	8.552255e-6
GO:0042129	regulation of T cell proliferation	9.013421e-6
GO:0070848	response to growth factor stimulus	9.208912e-6
GO:0006991	response to sterol depletion	9.515788e-6
GO:0051918	negative regulation of fibrinolysis	9.817408e-6
GO:0009628	response to abiotic stimulus	9.825048e-6
GO:0050974	detection of mechanical stimulus involved in sensory perception	9.862365e-6
GO:0002238	response to molecule of fungal origin	1.016837e-5
GO:0032861	activation of Rap GTPase activity	1.048951e-5
GO:0071363	cellular response to growth factor stimulus	1.108352e-5
GO:0050709	negative regulation of protein secretion	1.119947e-5
GO:0018149	peptide cross-linking	1.138583e-5
GO:0040018	positive regulation of multicellular organism growth	1.149800e-5
GO:0009101	glycoprotein biosynthetic process	1.152185e-5
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.166973e-5
GO:0002683	negative regulation of immune system process	1.174167e-5
GO:0002706	regulation of lymphocyte mediated immunity	1.212024e-5
GO:0008211	glucocorticoid metabolic process	1.231870e-5
GO:0042157	lipoprotein metabolic process	1.233510e-5
GO:0044259	multicellular organismal macromolecule metabolic process	1.332744e-5
GO:0032103	positive regulation of response to external stimulus	1.403676e-5
GO:0048545	response to steroid hormone stimulus	1.448952e-5
GO:0051272	positive regulation of cellular component movement	1.462704e-5
GO:0060621	negative regulation of cholesterol import	1.640627e-5
GO:0090030	regulation of steroid hormone biosynthetic process	1.691558e-5
GO:0006950	response to stress	1.694381e-5
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.698517e-5
GO:0006796	phosphate-containing compound metabolic process	1.717076e-5
GO:0032502	developmental process	1.836104e-5
GO:0071594	thymocyte aggregation	1.839167e-5
GO:0070887	cellular response to chemical stimulus	1.847588e-5
GO:0006066	alcohol metabolic process	2.026207e-5
GO:0001817	regulation of cytokine production	2.126531e-5
GO:0050713	negative regulation of interleukin-1 beta secretion	2.127026e-5
GO:0031645	negative regulation of neurological system process	2.198940e-5
GO:0032147	activation of protein kinase activity	2.227007e-5
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	2.380302e-5
GO:0046373	L-arabinose metabolic process	2.419010e-5
GO:0018924	mandelate metabolic process	2.419010e-5
GO:0007586	digestion	2.469217e-5
GO:0072358	cardiovascular system development	2.528146e-5
GO:0071593	lymphocyte aggregation	2.655240e-5
GO:0090022	regulation of neutrophil chemotaxis	2.656017e-5
GO:0030198	extracellular matrix organization	2.668358e-5
GO:0031647	regulation of protein stability	2.714848e-5
GO:0060343	trabecula formation	2.736436e-5
GO:0002690	positive regulation of leukocyte chemotaxis	2.748598e-5
GO:0001101	response to acid	2.752657e-5
GO:0045787	positive regulation of cell cycle	2.800561e-5
GO:0045670	regulation of osteoclast differentiation	2.815243e-5
GO:0048869	cellular developmental process	2.923143e-5
GO:0045088	regulation of innate immune response	2.932976e-5
GO:0050729	positive regulation of inflammatory response	3.022014e-5
GO:0090031	positive regulation of steroid hormone biosynthetic process	3.028256e-5
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	3.190475e-5
GO:0051533	positive regulation of NFAT protein import into nucleus	3.310729e-5
GO:0002739	regulation of cytokine secretion involved in immune response	3.325734e-5
GO:0051341	regulation of oxidoreductase activity	3.338508e-5
GO:0032651	regulation of interleukin-1 beta production	3.457813e-5
GO:0032691	negative regulation of interleukin-1 beta production	3.475031e-5
GO:0031399	regulation of protein modification process	3.480337e-5
GO:0006878	cellular copper ion homeostasis	3.482086e-5
GO:0003008	system process	3.556020e-5
GO:0048259	regulation of receptor-mediated endocytosis	3.646536e-5
GO:0051249	regulation of lymphocyte activation	3.727134e-5
GO:0034369	plasma lipoprotein particle remodeling	3.828623e-5
GO:0030155	regulation of cell adhesion	3.928912e-5
GO:0046637	regulation of alpha-beta T cell differentiation	3.939154e-5
GO:0043534	blood vessel endothelial cell migration	3.959325e-5
GO:0072676	lymphocyte migration	4.023474e-5
GO:0031589	cell-substrate adhesion	4.101682e-5
GO:0030261	chromosome condensation	4.157372e-5
GO:0055114	oxidation-reduction process	4.185293e-5
GO:0007243	intracellular protein kinase cascade	4.265454e-5
GO:0010755	regulation of plasminogen activation	4.332809e-5
GO:0050805	negative regulation of synaptic transmission	4.384062e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	4.424301e-5
GO:0060620	regulation of cholesterol import	4.426252e-5
GO:0051788	response to misfolded protein	4.430035e-5
GO:0001798	positive regulation of type IIa hypersensitivity	4.430035e-5
GO:0002699	positive regulation of immune effector process	4.476828e-5
GO:0009719	response to endogenous stimulus	4.551853e-5
GO:0019852	L-ascorbic acid metabolic process	4.706168e-5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	4.706437e-5
GO:0050862	positive regulation of T cell receptor signaling pathway	4.725316e-5
GO:0019752	carboxylic acid metabolic process	4.823453e-5
GO:0051004	regulation of lipoprotein lipase activity	4.846630e-5
GO:0045785	positive regulation of cell adhesion	4.998288e-5
GO:0007160	cell-matrix adhesion	5.061646e-5
GO:0031349	positive regulation of defense response	5.170718e-5
GO:0050982	detection of mechanical stimulus	5.207951e-5
GO:0014070	response to organic cyclic compound	5.249207e-5
GO:0050671	positive regulation of lymphocyte proliferation	5.328645e-5
GO:0071529	cementum mineralization	5.420718e-5
GO:0071495	cellular response to endogenous stimulus	5.507649e-5
GO:0042180	cellular ketone metabolic process	5.532956e-5
GO:0051239	regulation of multicellular organismal process	5.748685e-5
GO:0045471	response to ethanol	5.783945e-5
GO:0045672	positive regulation of osteoclast differentiation	5.821192e-5
GO:0006422	aspartyl-tRNA aminoacylation	5.887970e-5
GO:2000147	positive regulation of cell motility	5.950041e-5
GO:0010991	negative regulation of SMAD protein complex assembly	6.016570e-5
GO:0016310	phosphorylation	6.120070e-5
GO:0085029	extracellular matrix assembly	6.129206e-5
GO:0080134	regulation of response to stress	6.318574e-5
GO:0007080	mitotic metaphase plate congression	6.438019e-5
GO:0035556	intracellular signal transduction	6.542509e-5
GO:0071310	cellular response to organic substance	6.662748e-5
GO:0007219	Notch signaling pathway	6.664349e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	7.186529e-5
GO:0032880	regulation of protein localization	7.233004e-5
GO:0002883	regulation of hypersensitivity	7.267719e-5
GO:0032946	positive regulation of mononuclear cell proliferation	7.268775e-5
GO:0009605	response to external stimulus	7.493284e-5
GO:0030157	pancreatic juice secretion	7.534770e-5
GO:0045796	negative regulation of intestinal cholesterol absorption	7.849143e-5
GO:0010949	negative regulation of intestinal phytosterol absorption	7.849143e-5
GO:0032074	negative regulation of nuclease activity	7.849143e-5
GO:0042035	regulation of cytokine biosynthetic process	7.999926e-5
GO:0043405	regulation of MAP kinase activity	8.137684e-5
GO:0035966	response to topologically incorrect protein	8.268434e-5
GO:0043279	response to alkaloid	8.274462e-5
GO:0050710	negative regulation of cytokine secretion	8.342325e-5
GO:0051704	multi-organism process	8.396829e-5
GO:0022607	cellular component assembly	8.548793e-5
GO:0050715	positive regulation of cytokine secretion	8.720415e-5
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	8.775958e-5
GO:0032692	negative regulation of interleukin-1 production	8.835524e-5
GO:0048870	cell motility	8.880172e-5
GO:0032652	regulation of interleukin-1 production	9.017603e-5
GO:0055070	copper ion homeostasis	9.169529e-5
GO:0009611	response to wounding	9.182365e-5
GO:0070665	positive regulation of leukocyte proliferation	9.210078e-5
GO:0006954	inflammatory response	9.231075e-5
GO:0051241	negative regulation of multicellular organismal process	9.624016e-5
GO:0030335	positive regulation of cell migration	9.927868e-5
GO:0042110	T cell activation	1.026601e-4
GO:0071803	positive regulation of podosome assembly	1.033551e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	1.045479e-4
GO:0006955	immune response	1.098305e-4
GO:0006959	humoral immune response	1.098463e-4
GO:0045725	positive regulation of glycogen biosynthetic process	1.104221e-4
GO:0048012	hepatocyte growth factor receptor signaling pathway	1.104221e-4
GO:0050892	intestinal absorption	1.178885e-4
GO:0042993	positive regulation of transcription factor import into nucleus	1.180683e-4
GO:0044085	cellular component biogenesis	1.186627e-4
GO:0050994	regulation of lipid catabolic process	1.192124e-4
GO:0006767	water-soluble vitamin metabolic process	1.199354e-4
GO:0051970	negative regulation of transmission of nerve impulse	1.257912e-4
GO:0044242	cellular lipid catabolic process	1.272566e-4
GO:0046635	positive regulation of alpha-beta T cell activation	1.275713e-4
GO:0050777	negative regulation of immune response	1.276685e-4
GO:0010243	response to organic nitrogen	1.297360e-4
GO:0032071	regulation of endodeoxyribonuclease activity	1.298197e-4
GO:0014059	regulation of dopamine secretion	1.298937e-4
GO:0002376	immune system process	1.301424e-4
GO:0032891	negative regulation of organic acid transport	1.305350e-4
GO:0050711	negative regulation of interleukin-1 secretion	1.312821e-4
GO:0008299	isoprenoid biosynthetic process	1.314597e-4
GO:0019217	regulation of fatty acid metabolic process	1.339115e-4
GO:0045806	negative regulation of endocytosis	1.359584e-4
GO:0030194	positive regulation of blood coagulation	1.364024e-4
GO:0040011	locomotion	1.379988e-4
GO:0060415	muscle tissue morphogenesis	1.404438e-4
GO:0008038	neuron recognition	1.417348e-4
GO:0043434	response to peptide hormone stimulus	1.434904e-4
GO:0045824	negative regulation of innate immune response	1.443348e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.450849e-4
GO:0006706	steroid catabolic process	1.450849e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.454280e-4
GO:0051049	regulation of transport	1.471012e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.496540e-4
GO:0006629	lipid metabolic process	1.501745e-4
GO:0007249	I-kappaB kinase/NF-kappaB cascade	1.507489e-4
GO:0043542	endothelial cell migration	1.515121e-4
GO:0032925	regulation of activin receptor signaling pathway	1.527999e-4
GO:0034776	response to histamine	1.533931e-4
GO:0055002	striated muscle cell development	1.571613e-4
GO:0045060	negative thymic T cell selection	1.601355e-4
GO:0060696	regulation of phospholipid catabolic process	1.629024e-4
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	1.629024e-4
GO:0016477	cell migration	1.631951e-4
GO:0090023	positive regulation of neutrophil chemotaxis	1.633990e-4
GO:0043154	negative regulation of caspase activity	1.651636e-4
GO:0034381	plasma lipoprotein particle clearance	1.651748e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.684911e-4
GO:0044058	regulation of digestive system process	1.688004e-4
GO:0040017	positive regulation of locomotion	1.690251e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.692353e-4
GO:0031650	regulation of heat generation	1.711427e-4
GO:0051346	negative regulation of hydrolase activity	1.724699e-4
GO:0031329	regulation of cellular catabolic process	1.728925e-4
GO:0034375	high-density lipoprotein particle remodeling	1.758194e-4
GO:0042104	positive regulation of activated T cell proliferation	1.769141e-4
GO:0008037	cell recognition	1.799435e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.811668e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.853648e-4
GO:0060948	cardiac vascular smooth muscle cell development	1.857794e-4
GO:0048584	positive regulation of response to stimulus	1.862423e-4
GO:0031295	T cell costimulation	1.881637e-4
GO:0032352	positive regulation of hormone metabolic process	1.969807e-4
GO:0006082	organic acid metabolic process	1.982119e-4
GO:0031134	sister chromatid biorientation	1.999839e-4
GO:0001944	vasculature development	2.028848e-4
GO:0055008	cardiac muscle tissue morphogenesis	2.046885e-4
GO:0000165	MAPKKK cascade	2.051207e-4
GO:0015734	taurine transport	2.053401e-4
GO:0006994	positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	2.053401e-4
GO:0007618	mating	2.058633e-4
GO:0007601	visual perception	2.154733e-4
GO:0031017	exocrine pancreas development	2.162188e-4
GO:0044255	cellular lipid metabolic process	2.167591e-4
GO:0018345	protein palmitoylation	2.168808e-4
GO:0060191	regulation of lipase activity	2.193547e-4
GO:0045089	positive regulation of innate immune response	2.207384e-4
GO:0072376	protein activation cascade	2.249114e-4
GO:0044236	multicellular organismal metabolic process	2.290847e-4
GO:0050850	positive regulation of calcium-mediated signaling	2.327500e-4
GO:0006603	phosphocreatine metabolic process	2.363827e-4
GO:0032655	regulation of interleukin-12 production	2.393527e-4
GO:0051246	regulation of protein metabolic process	2.506890e-4
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	2.509513e-4
GO:0030856	regulation of epithelial cell differentiation	2.515710e-4
GO:0031667	response to nutrient levels	2.544081e-4
GO:0042403	thyroid hormone metabolic process	2.595785e-4
GO:0050820	positive regulation of coagulation	2.619786e-4
GO:0033344	cholesterol efflux	2.624863e-4
GO:0060402	calcium ion transport into cytosol	2.735311e-4
GO:0002718	regulation of cytokine production involved in immune response	2.740806e-4
GO:0034447	very-low-density lipoprotein particle clearance	2.768778e-4
GO:0006429	leucyl-tRNA aminoacylation	2.829363e-4
GO:0030100	regulation of endocytosis	2.852866e-4
GO:0034762	regulation of transmembrane transport	2.856827e-4
GO:0016199	axon midline choice point recognition	2.950386e-4
GO:0042628	mating plug formation	2.959712e-4
GO:0050953	sensory perception of light stimulus	2.990091e-4
GO:0055001	muscle cell development	3.048712e-4
GO:0008610	lipid biosynthetic process	3.083939e-4
GO:0043383	negative T cell selection	3.090870e-4
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3.108196e-4
GO:2000026	regulation of multicellular organismal development	3.124189e-4
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	3.126668e-4
GO:0045329	carnitine biosynthetic process	3.126668e-4
GO:0051130	positive regulation of cellular component organization	3.213368e-4
GO:0071247	cellular response to chromate	3.221448e-4
GO:0019060	intracellular transport of viral proteins in host cell	3.221448e-4
GO:0046967	cytosol to ER transport	3.221448e-4
GO:0007156	homophilic cell adhesion	3.249009e-4
GO:0044106	cellular amine metabolic process	3.355507e-4
GO:0042346	positive regulation of NF-kappaB import into nucleus	3.378336e-4
GO:0008207	C21-steroid hormone metabolic process	3.401678e-4
GO:0032026	response to magnesium ion	3.405619e-4
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	3.416984e-4
GO:0018958	phenol-containing compound metabolic process	3.472384e-4
GO:0002526	acute inflammatory response	3.482332e-4
GO:0009100	glycoprotein metabolic process	3.490442e-4
GO:0002697	regulation of immune effector process	3.510295e-4
GO:0006599	phosphagen metabolic process	3.517517e-4
GO:0006957	complement activation, alternative pathway	3.608304e-4
GO:0030595	leukocyte chemotaxis	3.645229e-4
GO:0051051	negative regulation of transport	3.649550e-4
GO:0051043	regulation of membrane protein ectodomain proteolysis	3.704252e-4
GO:0071260	cellular response to mechanical stimulus	3.743373e-4
GO:0051270	regulation of cellular component movement	3.762579e-4
GO:0009725	response to hormone stimulus	3.778688e-4
GO:0051055	negative regulation of lipid biosynthetic process	3.787357e-4
GO:0046628	positive regulation of insulin receptor signaling pathway	3.804229e-4
GO:0010717	regulation of epithelial to mesenchymal transition	3.826017e-4
GO:0034109	homotypic cell-cell adhesion	3.917774e-4
GO:0051048	negative regulation of secretion	3.957412e-4
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	3.974805e-4
GO:0061097	regulation of protein tyrosine kinase activity	3.984215e-4
GO:0016198	axon choice point recognition	4.010081e-4
GO:0015914	phospholipid transport	4.031792e-4
GO:0030154	cell differentiation	4.038254e-4
GO:0045833	negative regulation of lipid metabolic process	4.043391e-4
GO:0031117	positive regulation of microtubule depolymerization	4.080039e-4
GO:0030334	regulation of cell migration	4.142700e-4
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	4.159742e-4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4.204205e-4
GO:2000145	regulation of cell motility	4.420026e-4
GO:0042990	regulation of transcription factor import into nucleus	4.483670e-4
GO:0010759	positive regulation of macrophage chemotaxis	4.504863e-4
GO:0006700	C21-steroid hormone biosynthetic process	4.504863e-4
GO:0042446	hormone biosynthetic process	4.526125e-4
GO:0002819	regulation of adaptive immune response	4.555212e-4
GO:0060457	negative regulation of digestive system process	4.607092e-4
GO:0032070	regulation of deoxyribonuclease activity	4.607092e-4
GO:0019538	protein metabolic process	4.706849e-4
GO:0010565	regulation of cellular ketone metabolic process	4.727077e-4
GO:0006928	cellular component movement	4.792361e-4
GO:0070875	positive regulation of glycogen metabolic process	4.811612e-4
GO:0010757	negative regulation of plasminogen activation	4.923928e-4
GO:0031348	negative regulation of defense response	4.932386e-4
GO:0002763	positive regulation of myeloid leukocyte differentiation	4.961500e-4
GO:0051282	regulation of sequestering of calcium ion	4.975777e-4
GO:0009308	amine metabolic process	5.065909e-4
GO:0032846	positive regulation of homeostatic process	5.263490e-4
GO:0050906	detection of stimulus involved in sensory perception	5.302120e-4
GO:0071385	cellular response to glucocorticoid stimulus	5.335872e-4
GO:0071675	regulation of mononuclear cell migration	5.410420e-4
GO:0071840	cellular component organization or biogenesis	5.418552e-4
GO:0045927	positive regulation of growth	5.608861e-4
GO:0042364	water-soluble vitamin biosynthetic process	5.629343e-4
GO:0048247	lymphocyte chemotaxis	5.677574e-4
GO:0071827	plasma lipoprotein particle organization	5.767402e-4
GO:0060556	regulation of vitamin D biosynthetic process	5.938862e-4
GO:0042304	regulation of fatty acid biosynthetic process	5.978193e-4
GO:0030212	hyaluronan metabolic process	6.021665e-4
GO:0002761	regulation of myeloid leukocyte differentiation	6.069937e-4
GO:0060627	regulation of vesicle-mediated transport	6.132607e-4
GO:0032768	regulation of monooxygenase activity	6.141343e-4
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6.197498e-4
GO:0060326	cell chemotaxis	6.388549e-4
GO:0001649	osteoblast differentiation	6.421135e-4
GO:0050852	T cell receptor signaling pathway	6.485065e-4
GO:0040012	regulation of locomotion	6.538209e-4
GO:0008356	asymmetric cell division	6.539860e-4