Novel motif:166

name:	motif166_TAMAACTTTGS

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050908	detection of light stimulus involved in visual perception	2.137858e-12
GO:0042325	regulation of phosphorylation	1.745712e-10
GO:0007417	central nervous system development	5.392206e-10
GO:0048513	organ development	5.796861e-10
GO:0006586	indolalkylamine metabolic process	9.031385e-10
GO:0019220	regulation of phosphate metabolic process	1.316276e-9
GO:0001932	regulation of protein phosphorylation	1.649415e-9
GO:0016056	rhodopsin mediated signaling pathway	1.985552e-9
GO:0030049	muscle filament sliding	3.609051e-9
GO:0048660	regulation of smooth muscle cell proliferation	3.884730e-9
GO:0003012	muscle system process	4.606824e-9
GO:0070252	actin-mediated cell contraction	1.159440e-8
GO:0006569	tryptophan catabolic process	1.434171e-8
GO:0006568	tryptophan metabolic process	1.868352e-8
GO:0032501	multicellular organismal process	3.035098e-8
GO:0006936	muscle contraction	3.992397e-8
GO:0051338	regulation of transferase activity	4.794731e-8
GO:0045859	regulation of protein kinase activity	5.266657e-8
GO:0048856	anatomical structure development	5.616257e-8
GO:0009584	detection of visible light	6.106102e-8
GO:0009888	tissue development	6.803197e-8
GO:0030301	cholesterol transport	6.892248e-8
GO:0019805	quinolinate biosynthetic process	7.764623e-8
GO:0042769	DNA damage response, detection of DNA damage	8.062539e-8
GO:0019441	tryptophan catabolic process to kynurenine	9.085353e-8
GO:0015918	sterol transport	9.291895e-8
GO:0048731	system development	9.442847e-8
GO:0031116	positive regulation of microtubule polymerization	1.064466e-7
GO:0006937	regulation of muscle contraction	1.309006e-7
GO:0030048	actin filament-based movement	1.332247e-7
GO:0044057	regulation of system process	1.461197e-7
GO:0043549	regulation of kinase activity	2.173713e-7
GO:0070189	kynurenine metabolic process	2.238790e-7
GO:0048729	tissue morphogenesis	2.811014e-7
GO:0031399	regulation of protein modification process	3.078936e-7
GO:0019363	pyridine nucleotide biosynthetic process	3.622568e-7
GO:0009583	detection of light stimulus	3.653085e-7
GO:0032502	developmental process	3.805653e-7
GO:0019362	pyridine nucleotide metabolic process	8.949050e-7
GO:0002088	lens development in camera-type eye	9.525954e-7
GO:0018874	benzoate metabolic process	9.678965e-7
GO:0007320	insemination	1.000100e-6
GO:0006928	cellular component movement	1.011527e-6
GO:0090257	regulation of muscle system process	1.383181e-6
GO:0007220	Notch receptor processing	1.508025e-6
GO:0051915	induction of synaptic plasticity by chemical substance	2.030729e-6
GO:0046874	quinolinate metabolic process	2.039753e-6
GO:0018298	protein-chromophore linkage	2.093114e-6
GO:0052547	regulation of peptidase activity	2.131806e-6
GO:0019439	aromatic compound catabolic process	2.176137e-6
GO:0051346	negative regulation of hydrolase activity	2.236540e-6
GO:0014012	peripheral nervous system axon regeneration	2.258785e-6
GO:0009435	NAD biosynthetic process	2.377152e-6
GO:0007620	copulation	2.454483e-6
GO:0019674	NAD metabolic process	2.461073e-6
GO:0042946	glucoside transport	2.721445e-6
GO:0033344	cholesterol efflux	2.744522e-6
GO:0009586	rhodopsin mediated phototransduction	2.869154e-6
GO:0061097	regulation of protein tyrosine kinase activity	3.096201e-6
GO:0007026	negative regulation of microtubule depolymerization	3.343815e-6
GO:0042402	cellular biogenic amine catabolic process	3.384105e-6
GO:0034384	high-density lipoprotein particle clearance	3.447146e-6
GO:0047497	mitochondrion transport along microtubule	3.990130e-6
GO:0034516	response to vitamin B6	4.038085e-6
GO:0043420	anthranilate metabolic process	4.038085e-6
GO:0034379	very-low-density lipoprotein particle assembly	4.666634e-6
GO:0010466	negative regulation of peptidase activity	5.751388e-6
GO:0031112	positive regulation of microtubule polymerization or depolymerization	6.069395e-6
GO:0043616	keratinocyte proliferation	6.544056e-6
GO:0019359	nicotinamide nucleotide biosynthetic process	6.971250e-6
GO:0031114	regulation of microtubule depolymerization	7.206262e-6
GO:0072321	chaperone-mediated protein transport	8.231867e-6
GO:0007618	mating	8.377552e-6
GO:0022414	reproductive process	8.515999e-6
GO:0000003	reproduction	8.941117e-6
GO:0014912	negative regulation of smooth muscle cell migration	9.241856e-6
GO:0042632	cholesterol homeostasis	9.416967e-6
GO:0035988	chondrocyte proliferation	9.430697e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	9.501609e-6
GO:0007176	regulation of epidermal growth factor-activated receptor activity	9.710497e-6
GO:0007275	multicellular organismal development	9.946102e-6
GO:0046496	nicotinamide nucleotide metabolic process	1.081786e-5
GO:0031113	regulation of microtubule polymerization	1.089580e-5
GO:0002091	negative regulation of receptor internalization	1.092753e-5
GO:0031915	positive regulation of synaptic plasticity	1.160584e-5
GO:0009611	response to wounding	1.428990e-5
GO:0048661	positive regulation of smooth muscle cell proliferation	1.491707e-5
GO:0019371	cyclooxygenase pathway	1.766884e-5
GO:0051654	establishment of mitochondrion localization	1.960850e-5
GO:0003230	cardiac atrium development	2.375474e-5
GO:0035588	G-protein coupled purinergic receptor signaling pathway	2.489209e-5
GO:0010876	lipid localization	2.576211e-5
GO:0031102	neuron projection regeneration	2.583736e-5
GO:0016476	regulation of embryonic cell shape	2.614339e-5
GO:0003283	atrial septum development	2.655188e-5
GO:0030241	skeletal muscle myosin thick filament assembly	2.828650e-5
GO:0043242	negative regulation of protein complex disassembly	2.882536e-5
GO:0007420	brain development	2.900913e-5
GO:0048631	regulation of skeletal muscle tissue growth	2.932249e-5
GO:0048632	negative regulation of skeletal muscle tissue growth	3.036665e-5
GO:0021782	glial cell development	3.123420e-5
GO:0007517	muscle organ development	3.225107e-5
GO:0048739	cardiac muscle fiber development	3.260512e-5
GO:0032268	regulation of cellular protein metabolic process	3.314351e-5
GO:0002548	monocyte chemotaxis	3.470231e-5
GO:0048676	axon extension involved in development	3.571934e-5
GO:0032147	activation of protein kinase activity	3.800794e-5
GO:0006600	creatine metabolic process	3.830871e-5
GO:0015910	peroxisomal long-chain fatty acid import	4.131548e-5
GO:0070375	BMK cascade	4.512676e-5
GO:0072358	cardiovascular system development	4.590212e-5
GO:0031110	regulation of microtubule polymerization or depolymerization	4.774770e-5
GO:0009074	aromatic amino acid family catabolic process	4.803671e-5
GO:0035435	phosphate ion transmembrane transport	4.992315e-5
GO:0043068	positive regulation of programmed cell death	5.094316e-5
GO:0003289	atrial septum primum morphogenesis	5.103619e-5
GO:0006941	striated muscle contraction	5.157525e-5
GO:0003357	noradrenergic neuron differentiation	5.202954e-5
GO:0042158	lipoprotein biosynthetic process	5.725215e-5
GO:0043010	camera-type eye development	6.075334e-5
GO:0052548	regulation of endopeptidase activity	6.121254e-5
GO:0006869	lipid transport	6.169098e-5
GO:0006916	anti-apoptosis	6.514013e-5
GO:0051494	negative regulation of cytoskeleton organization	6.597575e-5
GO:0042157	lipoprotein metabolic process	7.205969e-5
GO:0006959	humoral immune response	7.419168e-5
GO:0043065	positive regulation of apoptosis	7.680020e-5
GO:0006733	oxidoreduction coenzyme metabolic process	7.911059e-5
GO:0001523	retinoid metabolic process	8.092709e-5
GO:0045073	regulation of chemokine biosynthetic process	8.301929e-5
GO:0043482	cellular pigment accumulation	8.465270e-5
GO:0043476	pigment accumulation	8.465270e-5
GO:0051348	negative regulation of transferase activity	8.495964e-5
GO:0071105	response to interleukin-11	8.776609e-5
GO:0060429	epithelium development	8.863085e-5
GO:0043403	skeletal muscle tissue regeneration	9.191703e-5
GO:0051574	positive regulation of histone H3-K9 methylation	9.297636e-5
GO:0009072	aromatic amino acid family metabolic process	9.386310e-5
GO:0003209	cardiac atrium morphogenesis	9.556290e-5
GO:0060821	inactivation of X chromosome by DNA methylation	9.900882e-5
GO:0001841	neural tube formation	9.941850e-5
GO:0048261	negative regulation of receptor-mediated endocytosis	1.026757e-4
GO:0045650	negative regulation of macrophage differentiation	1.026757e-4
GO:0045663	positive regulation of myoblast differentiation	1.064576e-4
GO:0008016	regulation of heart contraction	1.110406e-4
GO:0031960	response to corticosteroid stimulus	1.115478e-4
GO:0021915	neural tube development	1.139251e-4
GO:0046903	secretion	1.194826e-4
GO:0048854	brain morphogenesis	1.213992e-4
GO:0030505	inorganic diphosphate transport	1.228521e-4
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	1.266315e-4
GO:0007399	nervous system development	1.283783e-4
GO:0016101	diterpenoid metabolic process	1.288031e-4
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	1.291821e-4
GO:0051239	regulation of multicellular organismal process	1.308723e-4
GO:0006051	N-acetylmannosamine metabolic process	1.321531e-4
GO:0002384	hepatic immune response	1.330119e-4
GO:0009304	tRNA transcription	1.372286e-4
GO:0051901	positive regulation of mitochondrial depolarization	1.372286e-4
GO:0014706	striated muscle tissue development	1.385711e-4
GO:0042574	retinal metabolic process	1.424383e-4
GO:0043066	negative regulation of apoptosis	1.524929e-4
GO:0007340	acrosome reaction	1.540347e-4
GO:0060413	atrial septum morphogenesis	1.564082e-4
GO:0010942	positive regulation of cell death	1.566668e-4
GO:0060396	growth hormone receptor signaling pathway	1.612611e-4
GO:0009566	fertilization	1.615932e-4
GO:0014910	regulation of smooth muscle cell migration	1.626907e-4
GO:0002115	store-operated calcium entry	1.638214e-4
GO:0002009	morphogenesis of an epithelium	1.714062e-4
GO:0007166	cell surface receptor linked signaling pathway	1.736310e-4
GO:0009581	detection of external stimulus	1.751225e-4
GO:0045937	positive regulation of phosphate metabolic process	1.804028e-4
GO:0070508	cholesterol import	1.825507e-4
GO:0006469	negative regulation of protein kinase activity	1.869667e-4
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.893909e-4
GO:0000022	mitotic spindle elongation	1.893909e-4
GO:0060056	mammary gland involution	1.925811e-4
GO:0002328	pro-B cell differentiation	1.954513e-4
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.958918e-4
GO:0006721	terpenoid metabolic process	2.056911e-4
GO:0050713	negative regulation of interleukin-1 beta secretion	2.068337e-4
GO:0003065	positive regulation of heart rate by epinephrine	2.068337e-4
GO:0002762	negative regulation of myeloid leukocyte differentiation	2.073901e-4
GO:0045638	negative regulation of myeloid cell differentiation	2.103355e-4
GO:0003281	ventricular septum development	2.110396e-4
GO:0032675	regulation of interleukin-6 production	2.117753e-4
GO:0030029	actin filament-based process	2.141908e-4
GO:0019953	sexual reproduction	2.177480e-4
GO:0031103	axon regeneration	2.202078e-4
GO:0046219	indolalkylamine biosynthetic process	2.245897e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2.263114e-4
GO:0010506	regulation of autophagy	2.276741e-4
GO:0046425	regulation of JAK-STAT cascade	2.346835e-4
GO:0031400	negative regulation of protein modification process	2.380787e-4
GO:0045936	negative regulation of phosphate metabolic process	2.461607e-4
GO:0015742	alpha-ketoglutarate transport	2.541783e-4
GO:0048469	cell maturation	2.547871e-4
GO:0090341	negative regulation of secretion of lysosomal enzymes	2.610308e-4
GO:0090188	negative regulation of pancreatic juice secretion	2.610308e-4
GO:0000296	spermine transport	2.653966e-4
GO:0070669	response to interleukin-2	2.653966e-4
GO:0042981	regulation of apoptosis	2.657986e-4
GO:0051900	regulation of mitochondrial depolarization	2.709575e-4
GO:0007601	visual perception	2.723839e-4
GO:0001662	behavioral fear response	2.762089e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	2.859010e-4
GO:0015810	aspartate transport	2.876830e-4
GO:0048853	forebrain morphogenesis	2.895256e-4
GO:0048646	anatomical structure formation involved in morphogenesis	2.902873e-4
GO:0031296	B cell costimulation	2.997653e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	3.012027e-4
GO:0032273	positive regulation of protein polymerization	3.057922e-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	3.096115e-4
GO:0042327	positive regulation of phosphorylation	3.110956e-4
GO:0055001	muscle cell development	3.152316e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	3.290656e-4
GO:0071780	mitotic cell cycle G2/M transition checkpoint	3.305513e-4
GO:0042060	wound healing	3.309184e-4
GO:0050953	sensory perception of light stimulus	3.378647e-4
GO:0031018	endocrine pancreas development	3.406409e-4
GO:0045046	protein import into peroxisome membrane	3.415340e-4
GO:0043067	regulation of programmed cell death	3.434935e-4
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	3.542618e-4
GO:0035910	ascending aorta morphogenesis	3.542618e-4
GO:0033484	nitric oxide homeostasis	3.596358e-4
GO:0033673	negative regulation of kinase activity	3.615567e-4
GO:0040012	regulation of locomotion	3.619194e-4
GO:0046638	positive regulation of alpha-beta T cell differentiation	3.625835e-4
GO:0051606	detection of stimulus	3.644213e-4
GO:0042759	long-chain fatty acid biosynthetic process	3.663120e-4
GO:0009408	response to heat	3.729228e-4
GO:0034377	plasma lipoprotein particle assembly	3.767366e-4
GO:0060537	muscle tissue development	3.810768e-4
GO:0055088	lipid homeostasis	3.823761e-4
GO:0002209	behavioral defense response	3.852818e-4
GO:0046826	negative regulation of protein export from nucleus	3.876932e-4
GO:0048468	cell development	3.983630e-4
GO:0043069	negative regulation of programmed cell death	3.984809e-4
GO:0060304	regulation of phosphatidylinositol dephosphorylation	4.213899e-4
GO:0048747	muscle fiber development	4.222489e-4
GO:0001779	natural killer cell differentiation	4.230890e-4
GO:0060840	artery development	4.317445e-4
GO:2000685	positive regulation of cellular response to X-ray	4.323879e-4
GO:2001038	regulation of cellular response to drug	4.323879e-4
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	4.323879e-4
GO:0035978	histone H2A-S139 phosphorylation	4.323879e-4
GO:0031052	chromosome breakage	4.323879e-4
GO:0003131	mesodermal-endodermal cell signaling	4.323879e-4
GO:0032755	positive regulation of interleukin-6 production	4.327107e-4
GO:0007603	phototransduction, visible light	4.343530e-4
GO:0060271	cilium morphogenesis	4.374262e-4
GO:0006422	aspartyl-tRNA aminoacylation	4.399441e-4
GO:0048662	negative regulation of smooth muscle cell proliferation	4.453130e-4
GO:0009954	proximal/distal pattern formation	4.518352e-4
GO:0045578	negative regulation of B cell differentiation	4.523648e-4
GO:0006738	nicotinamide riboside catabolic process	4.537914e-4
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	4.537914e-4
GO:0006148	inosine catabolic process	4.537914e-4
GO:0046825	regulation of protein export from nucleus	4.576609e-4
GO:0051146	striated muscle cell differentiation	4.602834e-4
GO:0048869	cellular developmental process	4.631122e-4
GO:0042755	eating behavior	4.679354e-4
GO:0048593	camera-type eye morphogenesis	4.684725e-4
GO:0010897	negative regulation of triglyceride catabolic process	4.685503e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	4.685503e-4
GO:0048844	artery morphogenesis	4.707105e-4
GO:2000036	regulation of stem cell maintenance	4.827036e-4
GO:0034369	plasma lipoprotein particle remodeling	4.870299e-4
GO:0046637	regulation of alpha-beta T cell differentiation	4.992854e-4
GO:0051051	negative regulation of transport	5.127314e-4
GO:0048609	multicellular organismal reproductive process	5.286520e-4
GO:0042326	negative regulation of phosphorylation	5.341008e-4
GO:0060761	negative regulation of response to cytokine stimulus	5.346727e-4
GO:0006821	chloride transport	5.370306e-4
GO:0001654	eye development	5.457180e-4
GO:0032148	activation of protein kinase B activity	5.470644e-4
GO:0045738	negative regulation of DNA repair	5.522018e-4
GO:0046634	regulation of alpha-beta T cell activation	5.572718e-4
GO:0019369	arachidonic acid metabolic process	5.588578e-4
GO:0003181	atrioventricular valve morphogenesis	5.612911e-4
GO:0042572	retinol metabolic process	5.628385e-4
GO:0050711	negative regulation of interleukin-1 secretion	5.651851e-4
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	5.684334e-4
GO:0048537	mucosal-associated lymphoid tissue development	5.698614e-4
GO:0030091	protein repair	5.923120e-4
GO:0016265	death	5.994302e-4
GO:0008219	cell death	6.056744e-4
GO:0048738	cardiac muscle tissue development	6.079750e-4
GO:0006776	vitamin A metabolic process	6.127277e-4
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	6.160783e-4
GO:0048584	positive regulation of response to stimulus	6.186278e-4
GO:0031109	microtubule polymerization or depolymerization	6.308170e-4
GO:0003179	heart valve morphogenesis	6.368776e-4
GO:0014866	skeletal myofibril assembly	6.453159e-4
GO:0001934	positive regulation of protein phosphorylation	6.581305e-4
GO:0019087	transformation of host cell by virus	6.599858e-4
GO:0051384	response to glucocorticoid stimulus	6.654749e-4
GO:0006775	fat-soluble vitamin metabolic process	6.777880e-4
GO:0007016	cytoskeletal anchoring at plasma membrane	6.779201e-4
GO:0031032	actomyosin structure organization	6.779954e-4
GO:0060548	negative regulation of cell death	6.787618e-4
GO:0045540	regulation of cholesterol biosynthetic process	6.827866e-4
GO:0034754	cellular hormone metabolic process	6.850720e-4
GO:0071888	macrophage apoptosis	6.909441e-4
GO:0030334	regulation of cell migration	6.913340e-4
GO:0034605	cellular response to heat	6.966609e-4
GO:0072376	protein activation cascade	6.999946e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	7.047442e-4
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	7.047442e-4
GO:0071726	cellular response to diacyl bacterial lipopeptide	7.066231e-4
GO:0042496	detection of diacyl bacterial lipopeptide	7.066231e-4
GO:2000145	regulation of cell motility	7.106703e-4
GO:0006895	Golgi to endosome transport	7.111043e-4
GO:0030595	leukocyte chemotaxis	7.134158e-4
GO:0006915	apoptosis	7.138416e-4
GO:0009156	ribonucleoside monophosphate biosynthetic process	7.269091e-4
GO:0045649	regulation of macrophage differentiation	7.308042e-4
GO:0048514	blood vessel morphogenesis	7.440949e-4
GO:0032387	negative regulation of intracellular transport	7.471359e-4
GO:0009161	ribonucleoside monophosphate metabolic process	7.513857e-4
GO:0055002	striated muscle cell development	7.550576e-4
GO:0002089	lens morphogenesis in camera-type eye	7.551207e-4
GO:0006953	acute-phase response	7.737713e-4
GO:0002253	activation of immune response	7.841544e-4
GO:0007602	phototransduction	7.843884e-4
GO:0012501	programmed cell death	7.888381e-4
GO:0032269	negative regulation of cellular protein metabolic process	8.032040e-4
GO:0031330	negative regulation of cellular catabolic process	8.141952e-4
GO:0043086	negative regulation of catalytic activity	8.156167e-4
GO:0071877	regulation of adrenergic receptor signaling pathway	8.185447e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	8.215287e-4
GO:0044092	negative regulation of molecular function	8.287395e-4
GO:2000366	positive regulation of STAT protein import into nucleus	8.346996e-4
GO:0070091	glucagon secretion	8.346996e-4
GO:0045214	sarcomere organization	8.516485e-4
GO:0072227	metanephric macula densa development	8.564674e-4
GO:0072240	metanephric DCT cell differentiation	8.564674e-4
GO:0030261	chromosome condensation	8.572279e-4
GO:0009653	anatomical structure morphogenesis	8.705148e-4
GO:0001838	embryonic epithelial tube formation	8.742542e-4
GO:0030239	myofibril assembly	8.755043e-4
GO:0070970	interleukin-2 secretion	8.833232e-4
GO:0050793	regulation of developmental process	8.957048e-4
GO:0007229	integrin-mediated signaling pathway	9.016594e-4
GO:0032490	detection of molecule of bacterial origin	9.043093e-4
GO:0008045	motor axon guidance	9.159302e-4
GO:0040007	growth	9.313101e-4
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	9.376171e-4
GO:0046635	positive regulation of alpha-beta T cell activation	9.497856e-4
GO:0035404	histone-serine phosphorylation	9.514086e-4
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	9.682028e-4
GO:0034346	positive regulation of type III interferon production	9.772664e-4
GO:0007219	Notch signaling pathway	1.014203e-3
GO:0014009	glial cell proliferation	1.017055e-3
GO:0071104	response to interleukin-9	1.055734e-3
GO:0051068	dihydrolipoamide metabolic process	1.055734e-3
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.056480e-3
GO:0019915	lipid storage	1.056570e-3
GO:0030259	lipid glycosylation	1.062445e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	1.063731e-3
GO:0021700	developmental maturation	1.107673e-3
GO:0033152	immunoglobulin V(D)J recombination	1.145606e-3
GO:0051570	regulation of histone H3-K9 methylation	1.149969e-3
GO:0006032	chitin catabolic process	1.160662e-3
GO:0001781	neutrophil apoptosis	1.163219e-3
GO:0072384	organelle transport along microtubule	1.165959e-3
GO:0003170	heart valve development	1.177609e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.178810e-3
GO:0071477	cellular hypotonic salinity response	1.179723e-3
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.179723e-3
GO:0048160	primary follicle stage	1.179723e-3
GO:0070507	regulation of microtubule cytoskeleton organization	1.190551e-3
GO:0061061	muscle structure development	1.194590e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.205945e-3
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.213292e-3
GO:0034375	high-density lipoprotein particle remodeling	1.215788e-3
GO:2000648	positive regulation of stem cell proliferation	1.228372e-3
GO:0071354	cellular response to interleukin-6	1.235565e-3
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.247763e-3
GO:2000026	regulation of multicellular organismal development	1.261529e-3
GO:0010970	microtubule-based transport	1.273910e-3
GO:2000683	regulation of cellular response to X-ray	1.306267e-3
GO:0072148	epithelial cell fate commitment	1.306267e-3
GO:0007507	heart development	1.311301e-3
GO:0070050	neuron homeostasis	1.316241e-3
GO:0007416	synapse assembly	1.326386e-3
GO:0030154	cell differentiation	1.339473e-3
GO:0060563	neuroepithelial cell differentiation	1.350006e-3
GO:0003161	cardiac conduction system development	1.377798e-3
GO:0019233	sensory perception of pain	1.385789e-3
GO:0055094	response to lipoprotein stimulus	1.401849e-3
GO:0034694	response to prostaglandin stimulus	1.410860e-3
GO:0031099	regeneration	1.428841e-3
GO:0035090	maintenance of apical/basal cell polarity	1.429248e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.429248e-3
GO:0009582	detection of abiotic stimulus	1.435079e-3
GO:0048863	stem cell differentiation	1.435613e-3
GO:0014048	regulation of glutamate secretion	1.439277e-3
GO:0030705	cytoskeleton-dependent intracellular transport	1.440409e-3
GO:0016485	protein processing	1.443868e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	1.499171e-3
GO:0010941	regulation of cell death	1.504239e-3
GO:0032989	cellular component morphogenesis	1.506023e-3
GO:0043691	reverse cholesterol transport	1.525645e-3
GO:0006323	DNA packaging	1.541305e-3
GO:0006692	prostanoid metabolic process	1.548074e-3
GO:0007197	inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway	1.550231e-3
GO:0070779	D-aspartate import	1.562221e-3
GO:0035051	cardiac cell differentiation	1.577051e-3
GO:0006713	glucocorticoid catabolic process	1.584102e-3
GO:0050778	positive regulation of immune response	1.610618e-3
GO:0042427	serotonin biosynthetic process	1.615674e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.626337e-3
GO:0003231	cardiac ventricle development	1.628895e-3
GO:0050900	leukocyte migration	1.644248e-3
GO:0072175	epithelial tube formation	1.657330e-3
GO:0008544	epidermis development	1.668529e-3
GO:0071827	plasma lipoprotein particle organization	1.671748e-3
GO:0034622	cellular macromolecular complex assembly	1.720025e-3
GO:0043244	regulation of protein complex disassembly	1.751722e-3
GO:0007506	gonadal mesoderm development	1.759457e-3
GO:0045666	positive regulation of neuron differentiation	1.769773e-3
GO:0061162	establishment of monopolar cell polarity	1.806397e-3
GO:0048545	response to steroid hormone stimulus	1.811782e-3
GO:0055118	negative regulation of cardiac muscle contraction	1.813251e-3
GO:0070633	transepithelial transport	1.813827e-3
GO:0016331	morphogenesis of embryonic epithelium	1.852877e-3
GO:0050706	regulation of interleukin-1 beta secretion	1.865548e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	1.885136e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.892016e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.892035e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	1.919554e-3
GO:0032757	positive regulation of interleukin-8 production	1.924631e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	1.940090e-3
GO:0045079	negative regulation of chemokine biosynthetic process	1.940198e-3
GO:0042976	activation of Janus kinase activity	1.940198e-3
GO:0032728	positive regulation of interferon-beta production	1.947493e-3
GO:0006952	defense response	1.951983e-3
GO:0071345	cellular response to cytokine stimulus	1.989289e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	2.023286e-3
GO:0016572	histone phosphorylation	2.023822e-3
GO:0008054	cyclin catabolic process	2.025190e-3
GO:0003007	heart morphogenesis	2.033722e-3
GO:0043603	cellular amide metabolic process	2.045700e-3
GO:0045089	positive regulation of innate immune response	2.062180e-3
GO:0007156	homophilic cell adhesion	2.063086e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	2.083895e-3
GO:0014003	oligodendrocyte development	2.099443e-3
GO:0048634	regulation of muscle organ development	2.132268e-3
GO:0048675	axon extension	2.153359e-3
GO:0043589	skin morphogenesis	2.156811e-3
GO:0071702	organic substance transport	2.166341e-3
GO:0048769	sarcomerogenesis	2.169947e-3
GO:0007010	cytoskeleton organization	2.176994e-3
GO:0065009	regulation of molecular function	2.194190e-3
GO:0001843	neural tube closure	2.204898e-3
GO:0032940	secretion by cell	2.204980e-3
GO:0050790	regulation of catalytic activity	2.211024e-3
GO:0035587	purinergic receptor signaling pathway	2.213038e-3
GO:0071103	DNA conformation change	2.216989e-3
GO:0002090	regulation of receptor internalization	2.224790e-3
GO:0009266	response to temperature stimulus	2.229988e-3
GO:0071167	ribonucleoprotein complex import into nucleus	2.243749e-3
GO:0018924	mandelate metabolic process	2.243749e-3
GO:0035279	mRNA cleavage involved in gene silencing by miRNA	2.260127e-3
GO:0055098	response to low-density lipoprotein particle stimulus	2.271890e-3
GO:0070340	detection of bacterial lipopeptide	2.277540e-3
GO:0060118	vestibular receptor cell development	2.284902e-3
GO:0042363	fat-soluble vitamin catabolic process	2.299701e-3
GO:0001933	negative regulation of protein phosphorylation	2.319882e-3
GO:0035909	aorta morphogenesis	2.347562e-3
GO:0034121	regulation of toll-like receptor signaling pathway	2.356581e-3
GO:0016601	Rac protein signal transduction	2.376537e-3
GO:0031647	regulation of protein stability	2.385897e-3
GO:0007442	hindgut morphogenesis	2.416287e-3
GO:0051885	positive regulation of anagen	2.424445e-3
GO:0014835	myoblast cell differentiation involved in skeletal muscle regeneration	2.424445e-3
GO:0000086	G2/M transition of mitotic cell cycle	2.450946e-3
GO:0002224	toll-like receptor signaling pathway	2.487877e-3
GO:0042596	fear response	2.493708e-3
GO:0048541	Peyer's patch development	2.636429e-3
GO:0042063	gliogenesis	2.636703e-3
GO:0021509	roof plate formation	2.652448e-3
GO:0003008	system process	2.660492e-3
GO:0042692	muscle cell differentiation	2.746841e-3
GO:0050881	musculoskeletal movement	2.747592e-3
GO:0050776	regulation of immune response	2.757927e-3
GO:0030900	forebrain development	2.761303e-3
GO:0035458	cellular response to interferon-beta	2.767874e-3
GO:0051347	positive regulation of transferase activity	2.772178e-3
GO:0045860	positive regulation of protein kinase activity	2.774587e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	2.792776e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	2.792776e-3
GO:0072202	cell differentiation involved in metanephros development	2.815447e-3
GO:0001973	adenosine receptor signaling pathway	2.821722e-3
GO:0014061	regulation of norepinephrine secretion	2.836714e-3
GO:0002455	humoral immune response mediated by circulating immunoglobulin	2.837968e-3
GO:0002757	immune response-activating signal transduction	2.847238e-3
GO:0051129	negative regulation of cellular component organization	2.878999e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0014826	vein smooth muscle contraction	2.894301e-9
GO:0002087	regulation of respiratory gaseous exchange by neurological system process	5.261799e-9
GO:0001755	neural crest cell migration	1.251563e-8
GO:0070189	kynurenine metabolic process	4.210996e-8
GO:0035645	enteric smooth muscle cell differentiation	5.050280e-8
GO:0007497	posterior midgut development	5.050280e-8
GO:2000507	positive regulation of energy homeostasis	7.773370e-8
GO:2000253	positive regulation of feeding behavior	7.773370e-8
GO:0044065	regulation of respiratory system process	8.188364e-8
GO:0009992	cellular water homeostasis	8.304361e-8
GO:0070255	regulation of mucus secretion	1.605145e-7
GO:0014003	oligodendrocyte development	2.635163e-7
GO:0009072	aromatic amino acid family metabolic process	2.978584e-7
GO:0006568	tryptophan metabolic process	6.378878e-7
GO:0007512	adult heart development	7.077132e-7
GO:2000505	regulation of energy homeostasis	8.001147e-7
GO:0003219	cardiac right ventricle formation	1.025285e-6
GO:0043576	regulation of respiratory gaseous exchange	1.119100e-6
GO:0019432	triglyceride biosynthetic process	1.260702e-6
GO:0007018	microtubule-based movement	1.509654e-6
GO:0035411	catenin import into nucleus	1.616263e-6
GO:0042402	cellular biogenic amine catabolic process	2.293854e-6
GO:0070233	negative regulation of T cell apoptosis	2.445196e-6
GO:0002674	negative regulation of acute inflammatory response	2.549427e-6
GO:0048295	positive regulation of isotype switching to IgE isotypes	2.607505e-6
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	2.651109e-6
GO:0045653	negative regulation of megakaryocyte differentiation	2.834191e-6
GO:0051648	vesicle localization	2.919055e-6
GO:0019441	tryptophan catabolic process to kynurenine	3.092649e-6
GO:0042310	vasoconstriction	3.136785e-6
GO:0014043	negative regulation of neuron maturation	4.058512e-6
GO:0032463	negative regulation of protein homooligomerization	4.812177e-6
GO:0071985	multivesicular body sorting pathway	5.092090e-6
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	5.092090e-6
GO:0070256	negative regulation of mucus secretion	5.092090e-6
GO:0031100	organ regeneration	5.207402e-6
GO:0022010	central nervous system myelination	6.310562e-6
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.484025e-6
GO:0007416	synapse assembly	6.543346e-6
GO:0016080	synaptic vesicle targeting	6.765801e-6
GO:0006903	vesicle targeting	7.596720e-6
GO:0032241	positive regulation of nucleobase-containing compound transport	8.277158e-6
GO:0090066	regulation of anatomical structure size	8.319227e-6
GO:0030900	forebrain development	8.778703e-6
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	9.653754e-6
GO:0048384	retinoic acid receptor signaling pathway	9.899941e-6
GO:0048625	myoblast cell fate commitment	1.087090e-5
GO:0050808	synapse organization	1.117120e-5
GO:0008217	regulation of blood pressure	1.244856e-5
GO:0002021	response to dietary excess	1.251105e-5
GO:0097115	neurexin clustering	1.282703e-5
GO:0006928	cellular component movement	1.349338e-5
GO:0055118	negative regulation of cardiac muscle contraction	1.359749e-5
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.617277e-5
GO:0032252	secretory granule localization	1.666719e-5
GO:0050925	negative regulation of negative chemotaxis	1.759392e-5
GO:0051640	organelle localization	1.787372e-5
GO:0061032	visceral serous pericardium development	2.017453e-5
GO:0030326	embryonic limb morphogenesis	2.158910e-5
GO:0042733	embryonic digit morphogenesis	2.225333e-5
GO:0072177	mesonephric duct development	2.285218e-5
GO:0043486	histone exchange	2.350500e-5
GO:0051130	positive regulation of cellular component organization	2.485251e-5
GO:0045022	early endosome to late endosome transport	2.698373e-5
GO:0072171	mesonephric tubule morphogenesis	3.361527e-5
GO:0032273	positive regulation of protein polymerization	3.384149e-5
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	3.391990e-5
GO:0010665	regulation of cardiac muscle cell apoptosis	3.490330e-5
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	3.532892e-5
GO:0046621	negative regulation of organ growth	3.596906e-5
GO:0032900	negative regulation of neurotrophin production	3.657766e-5
GO:0032244	positive regulation of nucleoside transport	3.657766e-5
GO:0002639	positive regulation of immunoglobulin production	3.672887e-5
GO:0046627	negative regulation of insulin receptor signaling pathway	3.912381e-5
GO:0031099	regeneration	4.298736e-5
GO:0006072	glycerol-3-phosphate metabolic process	4.767926e-5
GO:0009074	aromatic amino acid family catabolic process	4.960152e-5
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	5.124539e-5
GO:0002115	store-operated calcium entry	5.124539e-5
GO:0034509	centromeric core chromatin assembly	5.264461e-5
GO:0034080	CenH3-containing nucleosome assembly at centromere	5.264461e-5
GO:0007158	neuron cell-cell adhesion	5.961042e-5
GO:0043254	regulation of protein complex assembly	6.266749e-5
GO:0051656	establishment of organelle localization	6.476999e-5
GO:0014829	vascular smooth muscle contraction	6.608076e-5
GO:0048709	oligodendrocyte differentiation	7.242472e-5
GO:0060065	uterus development	7.343632e-5
GO:0007157	heterophilic cell-cell adhesion	7.694011e-5
GO:0072208	metanephric smooth muscle tissue development	8.437921e-5
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	8.437921e-5
GO:0072259	metanephric interstitial cell development	8.437921e-5
GO:0072184	renal vesicle progenitor cell differentiation	8.437921e-5
GO:0072169	specification of posterior mesonephric tubule identity	8.437921e-5
GO:0072168	specification of anterior mesonephric tubule identity	8.437921e-5
GO:0001941	postsynaptic membrane organization	8.593048e-5
GO:0045329	carnitine biosynthetic process	8.646134e-5
GO:0060560	developmental growth involved in morphogenesis	8.704308e-5
GO:0019852	L-ascorbic acid metabolic process	8.864019e-5
GO:0051963	regulation of synapse assembly	9.094498e-5
GO:0048246	macrophage chemotaxis	9.710661e-5
GO:0051495	positive regulation of cytoskeleton organization	9.961275e-5
GO:0046590	embryonic leg morphogenesis	1.008810e-4
GO:0030049	muscle filament sliding	1.020779e-4
GO:0010463	mesenchymal cell proliferation	1.078199e-4
GO:0030322	stabilization of membrane potential	1.098828e-4
GO:0007522	visceral muscle development	1.149158e-4
GO:0021987	cerebral cortex development	1.196982e-4
GO:0006586	indolalkylamine metabolic process	1.225638e-4
GO:0042401	cellular biogenic amine biosynthetic process	1.244850e-4
GO:0072162	metanephric mesenchymal cell differentiation	1.249191e-4
GO:0051915	induction of synaptic plasticity by chemical substance	1.306249e-4
GO:0014032	neural crest cell development	1.353030e-4
GO:0070935	3'-UTR-mediated mRNA stabilization	1.374542e-4
GO:0002042	cell migration involved in sprouting angiogenesis	1.396744e-4
GO:0048619	embryonic hindgut morphogenesis	1.400652e-4
GO:0097120	receptor localization to synapse	1.509677e-4
GO:0072578	neurotransmitter-gated ion channel clustering	1.509677e-4
GO:0060323	head morphogenesis	1.589540e-4
GO:0046463	acylglycerol biosynthetic process	1.672476e-4
GO:0045210	FasL biosynthetic process	1.676194e-4
GO:0002554	serotonin secretion by platelet	1.713186e-4
GO:0072172	mesonephric tubule formation	1.771632e-4
GO:0014041	regulation of neuron maturation	1.771632e-4
GO:0050727	regulation of inflammatory response	1.779623e-4
GO:0035110	leg morphogenesis	1.944553e-4
GO:0015833	peptide transport	1.951168e-4
GO:0045212	neurotransmitter receptor biosynthetic process	1.969450e-4
GO:0007417	central nervous system development	1.988330e-4
GO:0072143	mesangial cell development	1.994079e-4
GO:0060982	coronary artery morphogenesis	1.994079e-4
GO:0050807	regulation of synapse organization	2.018017e-4
GO:0045668	negative regulation of osteoblast differentiation	2.047945e-4
GO:0030538	embryonic genitalia morphogenesis	2.056383e-4
GO:0048468	cell development	2.199331e-4
GO:0006954	inflammatory response	2.236058e-4
GO:0051650	establishment of vesicle localization	2.350208e-4
GO:0032462	regulation of protein homooligomerization	2.512142e-4
GO:0002637	regulation of immunoglobulin production	2.570916e-4
GO:0006916	anti-apoptosis	2.609374e-4
GO:0044140	negative regulation of growth of symbiont on or near host surface	2.709952e-4
GO:0006258	UDP-glucose catabolic process	2.709952e-4
GO:0019439	aromatic compound catabolic process	2.712446e-4
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	2.746346e-4
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	2.746346e-4
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	2.746346e-4
GO:0051099	positive regulation of binding	2.887109e-4
GO:0002040	sprouting angiogenesis	2.974843e-4
GO:0048713	regulation of oligodendrocyte differentiation	3.026675e-4
GO:0046504	glycerol ether biosynthetic process	3.064848e-4
GO:0060173	limb development	3.078905e-4
GO:0060763	mammary duct terminal end bud growth	3.092917e-4
GO:2000409	positive regulation of T cell extravasation	3.132012e-4
GO:0043310	negative regulation of eosinophil degranulation	3.132012e-4
GO:0035705	T-helper 17 cell chemotaxis	3.132012e-4
GO:0018872	arsonoacetate metabolic process	3.132012e-4
GO:0035696	monocyte extravasation	3.132012e-4
GO:0034766	negative regulation of ion transmembrane transport	3.135998e-4
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	3.135998e-4
GO:0014719	satellite cell activation	3.135998e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	3.135998e-4
GO:0021543	pallium development	3.176820e-4
GO:0072180	mesonephric duct morphogenesis	3.183688e-4
GO:0061325	cell proliferation involved in outflow tract morphogenesis	3.183688e-4
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	3.183688e-4
GO:0035385	Roundabout signaling pathway	3.222729e-4
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	3.222729e-4
GO:0072178	nephric duct morphogenesis	3.553115e-4
GO:0016199	axon midline choice point recognition	3.787198e-4
GO:0001505	regulation of neurotransmitter levels	3.789083e-4
GO:0042759	long-chain fatty acid biosynthetic process	3.826082e-4
GO:0033189	response to vitamin A	3.861564e-4
GO:0032693	negative regulation of interleukin-10 production	4.011523e-4
GO:0060011	Sertoli cell proliferation	4.068115e-4
GO:0060325	face morphogenesis	4.090644e-4
GO:0050906	detection of stimulus involved in sensory perception	4.121161e-4
GO:0010912	positive regulation of isomerase activity	4.238951e-4
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	4.238951e-4
GO:0061360	optic chiasma development	4.303429e-4
GO:2000597	positive regulation of optic nerve formation	4.303429e-4
GO:0035799	ureter maturation	4.303429e-4
GO:0021633	optic nerve structural organization	4.303429e-4
GO:0002442	serotonin secretion involved in inflammatory response	4.303429e-4
GO:0021650	vestibulocochlear nerve formation	4.303429e-4
GO:0032459	regulation of protein oligomerization	4.327360e-4
GO:0040011	locomotion	4.470721e-4
GO:0007442	hindgut morphogenesis	4.524810e-4
GO:0060973	cell migration involved in heart development	4.544074e-4
GO:0014821	phasic smooth muscle contraction	4.556948e-4
GO:0051290	protein heterotetramerization	4.561580e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	4.606217e-4
GO:0021795	cerebral cortex cell migration	4.780524e-4
GO:0001906	cell killing	4.814883e-4
GO:0000090	mitotic anaphase	5.132738e-4
GO:0042780	tRNA 3'-end processing	5.422221e-4
GO:0002576	platelet degranulation	5.422221e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	5.640172e-4
GO:0034259	negative regulation of Rho GTPase activity	5.640172e-4
GO:0097105	presynaptic membrane assembly	5.817406e-4
GO:0030522	intracellular receptor mediated signaling pathway	5.867448e-4
GO:0044087	regulation of cellular component biogenesis	5.871953e-4
GO:0033273	response to vitamin	5.896411e-4
GO:0045213	neurotransmitter receptor metabolic process	5.924811e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	5.931172e-4
GO:0009956	radial pattern formation	5.949593e-4
GO:0032271	regulation of protein polymerization	6.010349e-4
GO:0048793	pronephros development	6.116885e-4
GO:0097091	synaptic vesicle clustering	6.158470e-4
GO:0043044	ATP-dependent chromatin remodeling	6.218204e-4
GO:2000353	positive regulation of endothelial cell apoptosis	6.326966e-4
GO:0010830	regulation of myotube differentiation	6.340884e-4
GO:0060167	regulation of adenosine receptor signaling pathway	6.406121e-4
GO:0003406	retinal pigment epithelium development	6.406121e-4
GO:0006952	defense response	6.489456e-4
GO:0002329	pre-B cell differentiation	6.602271e-4
GO:0007017	microtubule-based process	6.890785e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	7.009476e-4
GO:0060324	face development	7.090030e-4
GO:0048484	enteric nervous system development	7.360305e-4
GO:0072017	distal tubule development	7.360305e-4
GO:0006071	glycerol metabolic process	7.386823e-4
GO:0045163	clustering of voltage-gated potassium channels	7.666217e-4
GO:0007172	signal complex assembly	7.666217e-4
GO:0032239	regulation of nucleobase-containing compound transport	7.666217e-4
GO:0050770	regulation of axonogenesis	7.675753e-4
GO:0046626	regulation of insulin receptor signaling pathway	7.686547e-4
GO:0060070	canonical Wnt receptor signaling pathway	7.699534e-4
GO:0045017	glycerolipid biosynthetic process	7.728768e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	7.861658e-4
GO:0060998	regulation of dendritic spine development	8.147554e-4
GO:0010815	bradykinin catabolic process	8.166621e-4
GO:0090303	positive regulation of wound healing	8.184695e-4
GO:0008291	acetylcholine metabolic process	8.184695e-4
GO:0046110	xanthine metabolic process	8.184695e-4
GO:0046653	tetrahydrofolate metabolic process	8.256469e-4
GO:0051965	positive regulation of synapse assembly	8.274965e-4
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	8.587677e-4
GO:0007409	axonogenesis	8.601702e-4
GO:0035726	common myeloid progenitor cell proliferation	8.716969e-4
GO:2000429	negative regulation of neutrophil aggregation	8.716969e-4
GO:2000469	negative regulation of peroxidase activity	8.716969e-4
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	8.716969e-4
GO:0002534	cytokine production involved in inflammatory response	8.716969e-4
GO:0032065	cortical protein anchoring	8.716969e-4
GO:0034276	kynurenic acid biosynthetic process	8.716969e-4
GO:2000243	positive regulation of reproductive process	8.853831e-4
GO:0030838	positive regulation of actin filament polymerization	9.021110e-4
GO:0045214	sarcomere organization	9.028211e-4
GO:0022029	telencephalon cell migration	9.209893e-4
GO:0001667	ameboidal cell migration	9.267265e-4
GO:0021827	postnatal olfactory bulb interneuron migration	9.361587e-4
GO:2000241	regulation of reproductive process	9.375607e-4
GO:0042981	regulation of apoptosis	9.661507e-4
GO:0048524	positive regulation of viral reproduction	9.811845e-4
GO:0042135	neurotransmitter catabolic process	9.935468e-4
GO:0072300	positive regulation of metanephric glomerulus development	1.016638e-3
GO:0042492	gamma-delta T cell differentiation	1.043655e-3
GO:0043309	regulation of eosinophil degranulation	1.043655e-3
GO:0010832	negative regulation of myotube differentiation	1.051339e-3
GO:0044089	positive regulation of cellular component biogenesis	1.054410e-3
GO:0031344	regulation of cell projection organization	1.060372e-3
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	1.070989e-3
GO:0032846	positive regulation of homeostatic process	1.085826e-3
GO:0072203	cell proliferation involved in metanephros development	1.086384e-3
GO:0001909	leukocyte mediated cytotoxicity	1.089310e-3
GO:0045777	positive regulation of blood pressure	1.102452e-3
GO:0040023	establishment of nucleus localization	1.102519e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.109506e-3
GO:0048293	regulation of isotype switching to IgE isotypes	1.119028e-3
GO:0043462	regulation of ATPase activity	1.121331e-3
GO:0019853	L-ascorbic acid biosynthetic process	1.137236e-3
GO:0097090	presynaptic membrane organization	1.153529e-3
GO:0050728	negative regulation of inflammatory response	1.168990e-3
GO:0032929	negative regulation of superoxide anion generation	1.198578e-3
GO:0060690	epithelial cell differentiation involved in salivary gland development	1.198578e-3
GO:0006312	mitotic recombination	1.198578e-3
GO:0030719	P granule organization	1.198578e-3
GO:0021782	glial cell development	1.199787e-3
GO:0043067	regulation of programmed cell death	1.225003e-3
GO:0070257	positive regulation of mucus secretion	1.255326e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.255326e-3
GO:0061205	paramesonephric duct development	1.255326e-3
GO:0019318	hexose metabolic process	1.265384e-3
GO:0010941	regulation of cell death	1.279958e-3
GO:0072176	nephric duct development	1.285211e-3
GO:0001560	regulation of cell growth by extracellular stimulus	1.306617e-3
GO:0048668	collateral sprouting	1.312936e-3
GO:0007420	brain development	1.327390e-3
GO:0031348	negative regulation of defense response	1.334645e-3
GO:0048745	smooth muscle tissue development	1.342386e-3
GO:0009952	anterior/posterior pattern specification	1.343930e-3
GO:0046168	glycerol-3-phosphate catabolic process	1.344422e-3
GO:0042350	GDP-L-fucose biosynthetic process	1.344422e-3
GO:0051154	negative regulation of striated muscle cell differentiation	1.344671e-3
GO:0072678	T cell migration	1.348470e-3
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	1.348470e-3
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	1.348470e-3
GO:0006518	peptide metabolic process	1.372146e-3
GO:0001764	neuron migration	1.377048e-3
GO:0010975	regulation of neuron projection development	1.379626e-3
GO:0002076	osteoblast development	1.446871e-3
GO:0016198	axon choice point recognition	1.463139e-3
GO:0000723	telomere maintenance	1.478662e-3
GO:0048812	neuron projection morphogenesis	1.479656e-3
GO:0035116	embryonic hindlimb morphogenesis	1.491203e-3
GO:0006935	chemotaxis	1.495351e-3
GO:0050880	regulation of blood vessel size	1.512799e-3
GO:0021885	forebrain cell migration	1.517575e-3
GO:0032892	positive regulation of organic acid transport	1.521111e-3
GO:0009584	detection of visible light	1.521111e-3
GO:0045348	positive regulation of MHC class II biosynthetic process	1.537533e-3
GO:0002790	peptide secretion	1.564059e-3
GO:0002026	regulation of the force of heart contraction	1.566531e-3
GO:0035150	regulation of tube size	1.578637e-3
GO:0050434	positive regulation of viral transcription	1.588151e-3
GO:0060259	regulation of feeding behavior	1.607796e-3
GO:0031347	regulation of defense response	1.627441e-3
GO:0046459	short-chain fatty acid metabolic process	1.638573e-3
GO:0050803	regulation of synapse structure and activity	1.649262e-3
GO:0097070	ductus arteriosus closure	1.686404e-3
GO:0015871	choline transport	1.686404e-3
GO:0006749	glutathione metabolic process	1.692318e-3
GO:0060322	head development	1.712509e-3
GO:0042330	taxis	1.725177e-3
GO:0070933	histone H4 deacetylation	1.768796e-3
GO:0009450	gamma-aminobutyric acid catabolic process	1.770602e-3
GO:0031334	positive regulation of protein complex assembly	1.772948e-3
GO:0031915	positive regulation of synaptic plasticity	1.776370e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.781286e-3
GO:0008016	regulation of heart contraction	1.785544e-3
GO:0061162	establishment of monopolar cell polarity	1.789630e-3
GO:0035108	limb morphogenesis	1.820461e-3
GO:0009605	response to external stimulus	1.834442e-3
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	1.859834e-3
GO:0071474	cellular hyperosmotic response	1.859834e-3
GO:0017121	phospholipid scrambling	1.859834e-3
GO:0014743	regulation of muscle hypertrophy	1.886778e-3
GO:0016445	somatic diversification of immunoglobulins	1.960656e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	1.992771e-3
GO:0016202	regulation of striated muscle tissue development	1.998573e-3
GO:0014045	establishment of endothelial blood-brain barrier	2.002054e-3
GO:0031346	positive regulation of cell projection organization	2.002520e-3
GO:0032101	regulation of response to external stimulus	2.017766e-3
GO:0015909	long-chain fatty acid transport	2.018500e-3
GO:0006006	glucose metabolic process	2.079822e-3
GO:0070100	negative regulation of chemokine-mediated signaling pathway	2.083009e-3
GO:0050923	regulation of negative chemotaxis	2.083009e-3
GO:0006657	CDP-choline pathway	2.083009e-3
GO:0021562	vestibulocochlear nerve development	2.087720e-3
GO:0007156	homophilic cell adhesion	2.095411e-3
GO:0007599	hemostasis	2.100938e-3
GO:0002446	neutrophil mediated immunity	2.128152e-3
GO:0030168	platelet activation	2.162549e-3
GO:0021799	cerebral cortex radially oriented cell migration	2.180492e-3
GO:0050792	regulation of viral reproduction	2.183111e-3
GO:0070252	actin-mediated cell contraction	2.223066e-3
GO:0002065	columnar/cuboidal epithelial cell differentiation	2.329918e-3
GO:0014823	response to activity	2.362904e-3
GO:0003215	cardiac right ventricle morphogenesis	2.379605e-3
GO:0042554	superoxide anion generation	2.435996e-3
GO:0048667	cell morphogenesis involved in neuron differentiation	2.477534e-3
GO:0048565	digestive tract development	2.480917e-3
GO:0050789	regulation of biological process	2.500877e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	2.516019e-3
GO:0070869	heterochromatin formation involved in chromatin silencing	2.516019e-3
GO:0072075	metanephric mesenchyme development	2.518146e-3
GO:0034968	histone lysine methylation	2.520309e-3
GO:0008015	blood circulation	2.582010e-3
GO:0045926	negative regulation of growth	2.590851e-3
GO:0042364	water-soluble vitamin biosynthetic process	2.607360e-3
GO:0019400	alditol metabolic process	2.607433e-3
GO:0050777	negative regulation of immune response	2.620194e-3
GO:0032526	response to retinoic acid	2.695781e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	2.712455e-3
GO:0031333	negative regulation of protein complex assembly	2.753969e-3
GO:0040038	polar body extrusion after meiotic divisions	2.777781e-3
GO:0048634	regulation of muscle organ development	2.806328e-3
GO:0006408	snRNA export from nucleus	2.809416e-3
GO:0000722	telomere maintenance via recombination	2.809416e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	2.845005e-3
GO:0021526	medial motor column neuron differentiation	2.845005e-3
GO:0021891	olfactory bulb interneuron development	2.851926e-3
GO:0050772	positive regulation of axonogenesis	2.870834e-3
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	2.884164e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	2.938262e-3
GO:0032535	regulation of cellular component size	2.966025e-3
GO:0071375	cellular response to peptide hormone stimulus	2.969031e-3
GO:0045880	positive regulation of smoothened signaling pathway	3.088534e-3
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	3.114182e-3
GO:0001937	negative regulation of endothelial cell proliferation	3.178591e-3
GO:0009309	amine biosynthetic process	3.183424e-3
GO:0051647	nucleus localization	3.209519e-3
GO:0043401	steroid hormone mediated signaling pathway	3.246364e-3
GO:2000193	positive regulation of fatty acid transport	3.319823e-3
GO:2000191	regulation of fatty acid transport	3.329955e-3
GO:0072133	metanephric mesenchyme morphogenesis	3.336509e-3
GO:0007389	pattern specification process	3.347848e-3
GO:0032990	cell part morphogenesis	3.441162e-3
GO:0001676	long-chain fatty acid metabolic process	3.471454e-3
GO:0047497	mitochondrion transport along microtubule	3.494779e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	3.503903e-3
GO:0032789	unsaturated monocarboxylic acid metabolic process	3.503903e-3
GO:0015739	sialic acid transport	3.503903e-3
GO:0032788	saturated monocarboxylic acid metabolic process	3.503903e-3
GO:0009611	response to wounding	3.528905e-3
GO:0032200	telomere organization	3.536045e-3
GO:0030072	peptide hormone secretion	3.554576e-3
GO:0045685	regulation of glial cell differentiation	3.666424e-3
GO:0005996	monosaccharide metabolic process	3.685997e-3
GO:0050907	detection of chemical stimulus involved in sensory perception	3.699323e-3
GO:0031133	regulation of axon diameter	3.712849e-3
GO:0010763	positive regulation of fibroblast migration	3.712849e-3
GO:0003006	developmental process involved in reproduction	3.722281e-3
GO:0033275	actin-myosin filament sliding	3.767554e-3
GO:0002828	regulation of type 2 immune response	3.767910e-3
GO:0050908	detection of light stimulus involved in visual perception	3.831635e-3
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	3.831635e-3
GO:0007269	neurotransmitter secretion	3.905046e-3
GO:0021904	dorsal/ventral neural tube patterning	3.909633e-3
GO:0006278	RNA-dependent DNA replication	3.909633e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	3.934715e-3
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	3.942919e-3
GO:0071460	cellular response to cell-matrix adhesion	3.942919e-3
GO:0003002	regionalization	4.006834e-3
GO:0009826	unidimensional cell growth	4.032385e-3
GO:0032210	regulation of telomere maintenance via telomerase	4.032385e-3
GO:0006837	serotonin transport	4.032602e-3
GO:0010611	regulation of cardiac muscle hypertrophy	4.155337e-3
GO:0051966	regulation of synaptic transmission, glutamatergic	4.212884e-3
GO:0061308	cardiac neural crest cell development involved in heart development	4.276941e-3
GO:0072166	posterior mesonephric tubule development	4.306448e-3
GO:0014807	regulation of somitogenesis	4.306448e-3
GO:0072194	kidney smooth muscle tissue development	4.306448e-3
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	4.306448e-3
GO:0006581	acetylcholine catabolic process	4.306448e-3
GO:0045918	negative regulation of cytolysis	4.345986e-3
GO:0006529	asparagine biosynthetic process	4.345986e-3
GO:0031641	regulation of myelination	4.355265e-3
GO:0032606	type I interferon production	4.416405e-3
GO:0051148	negative regulation of muscle cell differentiation	4.459610e-3
GO:0090193	positive regulation of glomerulus development	4.520628e-3
GO:0014050	negative regulation of glutamate secretion	4.520628e-3
GO:0032317	regulation of Rap GTPase activity	4.568435e-3
GO:0043627	response to estrogen stimulus	4.617427e-3
GO:0072044	collecting duct development	4.659873e-3
GO:0009583	detection of light stimulus	4.715899e-3
GO:0007614	short-term memory	4.808327e-3
GO:0048858	cell projection morphogenesis	4.813874e-3
GO:0021800	cerebral cortex tangential migration	4.839372e-3
GO:0045773	positive regulation of axon extension	4.915108e-3
GO:0014012	peripheral nervous system axon regeneration	4.977520e-3
GO:0072164	mesonephric tubule development	5.058828e-3
GO:0007548	sex differentiation	5.081940e-3
GO:0016180	snRNA processing	5.160677e-3
GO:0043388	positive regulation of DNA binding	5.171362e-3
GO:0033235	positive regulation of protein sumoylation	5.236645e-3
GO:0016337	cell-cell adhesion	5.244028e-3
GO:0007221	positive regulation of transcription of Notch receptor target	5.300040e-3
GO:0048676	axon extension involved in development	5.304060e-3
GO:0060040	retinal bipolar neuron differentiation	5.349867e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	5.349867e-3
GO:0016073	snRNA metabolic process	5.392248e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	5.392248e-3
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	5.497960e-3
GO:0071299	cellular response to vitamin A	5.549601e-3
GO:0001845	phagolysosome assembly	5.569979e-3
GO:0035418	protein localization to synapse	5.601603e-3
GO:0055123	digestive system development	5.776019e-3
GO:0032928	regulation of superoxide anion generation	5.800886e-3
GO:0014013	regulation of gliogenesis	5.824012e-3
GO:0006597	spermine biosynthetic process	5.855811e-3
GO:0002703	regulation of leukocyte mediated immunity	5.903515e-3
GO:0071205	protein localization to juxtaparanode region of axon	5.920677e-3
GO:0009755	hormone-mediated signaling pathway	5.948557e-3
GO:0031116	positive regulation of microtubule polymerization	5.967305e-3
GO:0050678	regulation of epithelial cell proliferation	5.989674e-3
GO:0006836	neurotransmitter transport	6.001478e-3
GO:0045346	regulation of MHC class II biosynthetic process	6.032382e-3
GO:0072221	metanephric distal convoluted tubule development	6.041828e-3
GO:0070327	thyroid hormone transport	6.041828e-3
GO:0051101	regulation of DNA binding	6.072767e-3
GO:0035455	response to interferon-alpha	6.166030e-3
GO:0032800	receptor biosynthetic process	6.169110e-3
GO:0051322	anaphase	6.181704e-3
GO:0065007	biological regulation	6.192323e-3
GO:0030833	regulation of actin filament polymerization	6.230345e-3
GO:0055091	phospholipid homeostasis	6.237045e-3
GO:0009214	cyclic nucleotide catabolic process	6.298441e-3
GO:0010970	microtubule-based transport	6.333494e-3
GO:0050794	regulation of cellular process	6.343384e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	6.375931e-3
GO:0048870	cell motility	6.421234e-3
GO:0032620	interleukin-17 production	6.474651e-3
GO:0002365	gamma-delta T cell lineage commitment	6.474651e-3
GO:0017085	response to insecticide	6.511468e-3
GO:0051049	regulation of transport	6.538308e-3
GO:0048598	embryonic morphogenesis	6.542081e-3
GO:0048739	cardiac muscle fiber development	6.549893e-3
GO:0002697	regulation of immune effector process	6.601614e-3
GO:0045807	positive regulation of endocytosis	6.697157e-3
GO:0071300	cellular response to retinoic acid	6.749635e-3