Novel motif:81

name:	motif81_NGCAGAA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032501	multicellular organismal process	2.309648e-35
GO:0003008	system process	5.682974e-29
GO:0050896	response to stimulus	7.997309e-26
GO:0048731	system development	3.910117e-24
GO:0048856	anatomical structure development	2.210390e-23
GO:0007275	multicellular organismal development	1.416824e-21
GO:0007154	cell communication	2.137722e-21
GO:0032502	developmental process	5.603505e-21
GO:0003012	muscle system process	4.681002e-20
GO:0048513	organ development	6.756789e-20
GO:0023052	signaling	1.737550e-18
GO:0006950	response to stress	1.820951e-18
GO:0065007	biological regulation	9.178202e-18
GO:0051716	cellular response to stimulus	2.745065e-17
GO:0030730	sequestering of triglyceride	5.533141e-17
GO:0009888	tissue development	1.027961e-16
GO:0048583	regulation of response to stimulus	2.936310e-16
GO:0006936	muscle contraction	3.263141e-16
GO:0007165	signal transduction	1.149214e-15
GO:0032101	regulation of response to external stimulus	3.446555e-15
GO:0050789	regulation of biological process	6.276252e-15
GO:0031424	keratinization	8.253442e-15
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.708290e-14
GO:0080134	regulation of response to stress	4.619301e-14
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	5.404475e-14
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	9.154120e-14
GO:0051043	regulation of membrane protein ectodomain proteolysis	1.225906e-13
GO:0010466	negative regulation of peptidase activity	1.705826e-13
GO:0009611	response to wounding	2.531144e-13
GO:0065008	regulation of biological quality	2.772024e-13
GO:0002682	regulation of immune system process	2.957823e-13
GO:0002376	immune system process	3.363715e-13
GO:0043086	negative regulation of catalytic activity	3.568101e-13
GO:0007166	cell surface receptor linked signaling pathway	9.103405e-13
GO:0052547	regulation of peptidase activity	9.463359e-13
GO:0009266	response to temperature stimulus	1.045810e-12
GO:0031099	regeneration	1.068680e-12
GO:0042221	response to chemical stimulus	1.156611e-12
GO:0070164	negative regulation of adiponectin secretion	2.398281e-12
GO:0060355	positive regulation of cell adhesion molecule production	2.398281e-12
GO:0035505	positive regulation of myosin light chain kinase activity	2.398281e-12
GO:0006952	defense response	2.853220e-12
GO:0007267	cell-cell signaling	3.074372e-12
GO:0019915	lipid storage	3.658579e-12
GO:0030855	epithelial cell differentiation	3.881178e-12
GO:0051346	negative regulation of hydrolase activity	4.495485e-12
GO:0009408	response to heat	5.727763e-12
GO:0050995	negative regulation of lipid catabolic process	6.494326e-12
GO:0050877	neurological system process	6.781789e-12
GO:0070163	regulation of adiponectin secretion	8.118651e-12
GO:0050727	regulation of inflammatory response	8.301971e-12
GO:0031347	regulation of defense response	8.404318e-12
GO:0014866	skeletal myofibril assembly	8.467480e-12
GO:0030029	actin filament-based process	9.861392e-12
GO:0007155	cell adhesion	1.267266e-11
GO:0048869	cellular developmental process	1.299117e-11
GO:0006928	cellular component movement	1.546580e-11
GO:0030154	cell differentiation	1.626616e-11
GO:0051234	establishment of localization	1.918611e-11
GO:0009725	response to hormone stimulus	2.236132e-11
GO:0051179	localization	2.697097e-11
GO:0010829	negative regulation of glucose transport	3.867040e-11
GO:0009913	epidermal cell differentiation	4.859974e-11
GO:0044060	regulation of endocrine process	5.149020e-11
GO:0002684	positive regulation of immune system process	6.027171e-11
GO:0048545	response to steroid hormone stimulus	7.839838e-11
GO:0050794	regulation of cellular process	9.023188e-11
GO:0042060	wound healing	1.029920e-10
GO:0043500	muscle adaptation	1.210753e-10
GO:0051240	positive regulation of multicellular organismal process	1.219175e-10
GO:0040007	growth	1.323885e-10
GO:0048584	positive regulation of response to stimulus	1.351991e-10
GO:0007610	behavior	1.663907e-10
GO:0031915	positive regulation of synaptic plasticity	1.688393e-10
GO:0007015	actin filament organization	1.693916e-10
GO:0030216	keratinocyte differentiation	2.570333e-10
GO:0001660	fever generation	2.778394e-10
GO:0030049	muscle filament sliding	2.853470e-10
GO:0030048	actin filament-based movement	3.319338e-10
GO:0048585	negative regulation of response to stimulus	3.559627e-10
GO:0051480	cytosolic calcium ion homeostasis	3.607388e-10
GO:0070252	actin-mediated cell contraction	5.041062e-10
GO:0045785	positive regulation of cell adhesion	5.243123e-10
GO:0001775	cell activation	5.651952e-10
GO:0009605	response to external stimulus	5.814760e-10
GO:0044092	negative regulation of molecular function	6.401272e-10
GO:0008544	epidermis development	7.008886e-10
GO:0048747	muscle fiber development	7.284274e-10
GO:0048739	cardiac muscle fiber development	7.574204e-10
GO:0050778	positive regulation of immune response	8.136744e-10
GO:0042993	positive regulation of transcription factor import into nucleus	8.351982e-10
GO:0042990	regulation of transcription factor import into nucleus	8.755144e-10
GO:0031960	response to corticosteroid stimulus	9.176930e-10
GO:0002439	chronic inflammatory response to antigenic stimulus	9.866799e-10
GO:0052548	regulation of endopeptidase activity	1.007073e-9
GO:0009617	response to bacterium	1.017222e-9
GO:0034605	cellular response to heat	1.088883e-9
GO:0030036	actin cytoskeleton organization	1.257394e-9
GO:0007163	establishment or maintenance of cell polarity	1.267876e-9
GO:0006810	transport	1.282581e-9
GO:0010951	negative regulation of endopeptidase activity	1.421785e-9
GO:0045408	regulation of interleukin-6 biosynthetic process	1.617573e-9
GO:0050776	regulation of immune response	1.860141e-9
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.885191e-9
GO:0065009	regulation of molecular function	1.968771e-9
GO:0002673	regulation of acute inflammatory response	2.032139e-9
GO:0048518	positive regulation of biological process	2.044923e-9
GO:0035690	cellular response to drug	2.305230e-9
GO:0051384	response to glucocorticoid stimulus	2.382133e-9
GO:0060558	regulation of calcidiol 1-monooxygenase activity	2.456836e-9
GO:0007399	nervous system development	2.793614e-9
GO:0008015	blood circulation	3.500008e-9
GO:0006955	immune response	3.501810e-9
GO:0003013	circulatory system process	3.753991e-9
GO:0007631	feeding behavior	4.079187e-9
GO:0051293	establishment of spindle localization	4.186813e-9
GO:0014050	negative regulation of glutamate secretion	4.648768e-9
GO:0007517	muscle organ development	4.840073e-9
GO:0030241	skeletal muscle myosin thick filament assembly	5.135920e-9
GO:0010035	response to inorganic substance	5.171874e-9
GO:0002576	platelet degranulation	5.633973e-9
GO:0006811	ion transport	6.839613e-9
GO:0010646	regulation of cell communication	6.996575e-9
GO:0006939	smooth muscle contraction	8.912663e-9
GO:0032846	positive regulation of homeostatic process	9.966253e-9
GO:0007204	elevation of cytosolic calcium ion concentration	1.146968e-8
GO:0031110	regulation of microtubule polymerization or depolymerization	1.158636e-8
GO:0008037	cell recognition	1.182030e-8
GO:0070887	cellular response to chemical stimulus	1.212722e-8
GO:0006874	cellular calcium ion homeostasis	1.348563e-8
GO:0030593	neutrophil chemotaxis	1.355451e-8
GO:0032940	secretion by cell	1.381496e-8
GO:0032879	regulation of localization	1.395158e-8
GO:0045410	positive regulation of interleukin-6 biosynthetic process	1.406074e-8
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.626956e-8
GO:0055074	calcium ion homeostasis	1.723251e-8
GO:0072503	cellular divalent inorganic cation homeostasis	1.737604e-8
GO:0012501	programmed cell death	1.879103e-8
GO:0006915	apoptosis	1.931555e-8
GO:0001659	temperature homeostasis	1.955823e-8
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.986017e-8
GO:0043627	response to estrogen stimulus	2.178075e-8
GO:0030239	myofibril assembly	2.194731e-8
GO:0032103	positive regulation of response to external stimulus	2.224485e-8
GO:0032757	positive regulation of interleukin-8 production	2.452870e-8
GO:0051606	detection of stimulus	2.588247e-8
GO:0032892	positive regulation of organic acid transport	2.896755e-8
GO:0033129	positive regulation of histone phosphorylation	2.991101e-8
GO:0015698	inorganic anion transport	3.011401e-8
GO:0030010	establishment of cell polarity	3.100482e-8
GO:0043278	response to morphine	3.156225e-8
GO:0071310	cellular response to organic substance	4.072211e-8
GO:0007548	sex differentiation	4.084025e-8
GO:0055002	striated muscle cell development	4.286016e-8
GO:0055001	muscle cell development	4.510409e-8
GO:0031652	positive regulation of heat generation	4.548340e-8
GO:0051592	response to calcium ion	5.424750e-8
GO:0031622	positive regulation of fever generation	5.589410e-8
GO:0032886	regulation of microtubule-based process	5.790499e-8
GO:0009653	anatomical structure morphogenesis	5.910754e-8
GO:0002544	chronic inflammatory response	6.510857e-8
GO:0050729	positive regulation of inflammatory response	6.667646e-8
GO:0007268	synaptic transmission	6.672475e-8
GO:0009719	response to endogenous stimulus	6.765443e-8
GO:0070507	regulation of microtubule cytoskeleton organization	7.294203e-8
GO:0051707	response to other organism	7.512055e-8
GO:0019805	quinolinate biosynthetic process	7.596705e-8
GO:0009987	cellular process	7.639517e-8
GO:0072507	divalent inorganic cation homeostasis	8.292204e-8
GO:0010033	response to organic substance	8.330416e-8
GO:0034762	regulation of transmembrane transport	8.993245e-8
GO:0007417	central nervous system development	9.408599e-8
GO:0051094	positive regulation of developmental process	9.673896e-8
GO:0048871	multicellular organismal homeostasis	1.001709e-7
GO:0042745	circadian sleep/wake cycle	1.006346e-7
GO:0040001	establishment of mitotic spindle localization	1.017893e-7
GO:0016049	cell growth	1.066976e-7
GO:0016265	death	1.223980e-7
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.234511e-7
GO:0048251	elastic fiber assembly	1.256637e-7
GO:0007156	homophilic cell adhesion	1.279810e-7
GO:0007611	learning or memory	1.360937e-7
GO:0030505	inorganic diphosphate transport	1.426771e-7
GO:0051239	regulation of multicellular organismal process	1.430488e-7
GO:0023051	regulation of signaling	1.511221e-7
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.538613e-7
GO:0000132	establishment of mitotic spindle orientation	1.544565e-7
GO:0051050	positive regulation of transport	1.624780e-7
GO:0050870	positive regulation of T cell activation	1.661158e-7
GO:0090287	regulation of cellular response to growth factor stimulus	1.794592e-7
GO:0008219	cell death	1.864674e-7
GO:0048771	tissue remodeling	1.910151e-7
GO:0090316	positive regulation of intracellular protein transport	1.938158e-7
GO:0033157	regulation of intracellular protein transport	1.972794e-7
GO:0048522	positive regulation of cellular process	2.427574e-7
GO:0042246	tissue regeneration	2.452752e-7
GO:0050867	positive regulation of cell activation	2.479077e-7
GO:0002675	positive regulation of acute inflammatory response	2.553056e-7
GO:0031349	positive regulation of defense response	2.623160e-7
GO:0043501	skeletal muscle adaptation	2.669182e-7
GO:0051235	maintenance of location	2.814033e-7
GO:0040011	locomotion	3.111807e-7
GO:0006821	chloride transport	3.238129e-7
GO:0051251	positive regulation of lymphocyte activation	3.358497e-7
GO:0061061	muscle structure development	3.415924e-7
GO:0042306	regulation of protein import into nucleus	3.443312e-7
GO:0051298	centrosome duplication	3.480792e-7
GO:0044057	regulation of system process	3.666464e-7
GO:0010927	cellular component assembly involved in morphogenesis	3.703246e-7
GO:0014048	regulation of glutamate secretion	3.709489e-7
GO:0050890	cognition	3.790033e-7
GO:0035330	regulation of hippo signaling cascade	3.862439e-7
GO:0042592	homeostatic process	3.924763e-7
GO:0055065	metal ion homeostasis	3.951845e-7
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	4.027107e-7
GO:0009991	response to extracellular stimulus	4.114456e-7
GO:0034114	regulation of heterotypic cell-cell adhesion	4.217019e-7
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4.217019e-7
GO:0007010	cytoskeleton organization	4.715407e-7
GO:0031032	actomyosin structure organization	4.738628e-7
GO:0006875	cellular metal ion homeostasis	5.048764e-7
GO:0032092	positive regulation of protein binding	5.117922e-7
GO:0048512	circadian behavior	5.363354e-7
GO:0022410	circadian sleep/wake cycle process	5.428861e-7
GO:0032989	cellular component morphogenesis	5.593913e-7
GO:0009607	response to biotic stimulus	5.913831e-7
GO:0030168	platelet activation	5.995631e-7
GO:0042307	positive regulation of protein import into nucleus	6.014452e-7
GO:0014805	smooth muscle adaptation	6.160144e-7
GO:0022008	neurogenesis	6.489937e-7
GO:0018149	peptide cross-linking	6.648326e-7
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	6.678829e-7
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	6.679157e-7
GO:0009968	negative regulation of signal transduction	6.936239e-7
GO:0031112	positive regulation of microtubule polymerization or depolymerization	6.975643e-7
GO:0033591	response to L-ascorbic acid	7.008074e-7
GO:0060429	epithelium development	7.268179e-7
GO:0007622	rhythmic behavior	7.360496e-7
GO:0045137	development of primary sexual characteristics	7.495270e-7
GO:0002697	regulation of immune effector process	7.860687e-7
GO:0085029	extracellular matrix assembly	7.918026e-7
GO:0051249	regulation of lymphocyte activation	7.941730e-7
GO:0055082	cellular chemical homeostasis	8.046805e-7
GO:0019226	transmission of nerve impulse	8.101562e-7
GO:0032388	positive regulation of intracellular transport	8.112166e-7
GO:0071495	cellular response to endogenous stimulus	8.306646e-7
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	8.327215e-7
GO:0051336	regulation of hydrolase activity	8.923312e-7
GO:0071402	cellular response to lipoprotein particle stimulus	8.987074e-7
GO:0006941	striated muscle contraction	8.992370e-7
GO:0046627	negative regulation of insulin receptor signaling pathway	9.344944e-7
GO:0045214	sarcomere organization	9.853156e-7
GO:2000193	positive regulation of fatty acid transport	9.854214e-7
GO:0050790	regulation of catalytic activity	1.006053e-6
GO:0042310	vasoconstriction	1.017733e-6
GO:0008038	neuron recognition	1.059411e-6
GO:0006873	cellular ion homeostasis	1.069913e-6
GO:0002237	response to molecule of bacterial origin	1.083629e-6
GO:0010332	response to gamma radiation	1.114872e-6
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	1.150862e-6
GO:0002696	positive regulation of leukocyte activation	1.207284e-6
GO:0050865	regulation of cell activation	1.226061e-6
GO:0046827	positive regulation of protein export from nucleus	1.240386e-6
GO:0046874	quinolinate metabolic process	1.262654e-6
GO:0019725	cellular homeostasis	1.278667e-6
GO:0021987	cerebral cortex development	1.302658e-6
GO:0034764	positive regulation of transmembrane transport	1.356091e-6
GO:0031109	microtubule polymerization or depolymerization	1.363913e-6
GO:0050863	regulation of T cell activation	1.400824e-6
GO:0030240	skeletal muscle thin filament assembly	1.404693e-6
GO:0045076	regulation of interleukin-2 biosynthetic process	1.417115e-6
GO:0050906	detection of stimulus involved in sensory perception	1.453669e-6
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.524510e-6
GO:0030003	cellular cation homeostasis	1.527393e-6
GO:0071840	cellular component organization or biogenesis	1.557323e-6
GO:0051047	positive regulation of secretion	1.567347e-6
GO:0051704	multi-organism process	1.572319e-6
GO:0022409	positive regulation of cell-cell adhesion	1.584098e-6
GO:0010631	epithelial cell migration	1.594261e-6
GO:0033198	response to ATP	1.637541e-6
GO:0002708	positive regulation of lymphocyte mediated immunity	1.645955e-6
GO:0030595	leukocyte chemotaxis	1.741861e-6
GO:0033127	regulation of histone phosphorylation	1.862830e-6
GO:0002253	activation of immune response	1.864642e-6
GO:0032755	positive regulation of interleukin-6 production	1.895262e-6
GO:0010648	negative regulation of cell communication	1.953101e-6
GO:0030198	extracellular matrix organization	1.969721e-6
GO:0003018	vascular process in circulatory system	2.043115e-6
GO:0030182	neuron differentiation	2.232686e-6
GO:0010193	response to ozone	2.234571e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	2.320903e-6
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.321505e-6
GO:0006935	chemotaxis	2.334031e-6
GO:0007613	memory	2.337036e-6
GO:0050801	ion homeostasis	2.356079e-6
GO:0002694	regulation of leukocyte activation	2.393308e-6
GO:0043503	skeletal muscle fiber adaptation	2.427914e-6
GO:0008406	gonad development	2.516816e-6
GO:0023057	negative regulation of signaling	2.525035e-6
GO:0051725	protein de-ADP-ribosylation	2.552800e-6
GO:0006968	cellular defense response	2.581631e-6
GO:0031667	response to nutrient levels	2.628556e-6
GO:0010470	regulation of gastrulation	2.701225e-6
GO:0048608	reproductive structure development	2.863943e-6
GO:0031113	regulation of microtubule polymerization	3.079708e-6
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3.202834e-6
GO:0009628	response to abiotic stimulus	3.242734e-6
GO:0000302	response to reactive oxygen species	3.322124e-6
GO:0046903	secretion	3.336658e-6
GO:0051348	negative regulation of transferase activity	3.363803e-6
GO:0009409	response to cold	3.388637e-6
GO:0034516	response to vitamin B6	3.742811e-6
GO:0043420	anthranilate metabolic process	3.742811e-6
GO:0051649	establishment of localization in cell	3.893994e-6
GO:0042345	regulation of NF-kappaB import into nucleus	3.913242e-6
GO:0045765	regulation of angiogenesis	3.935520e-6
GO:0045086	positive regulation of interleukin-2 biosynthetic process	3.951041e-6
GO:0051049	regulation of transport	3.973527e-6
GO:0007612	learning	3.976693e-6
GO:0043526	neuroprotection	4.001899e-6
GO:0060401	cytosolic calcium ion transport	4.050573e-6
GO:0032308	positive regulation of prostaglandin secretion	4.243152e-6
GO:0051017	actin filament bundle assembly	4.305457e-6
GO:0051641	cellular localization	4.673824e-6
GO:0050994	regulation of lipid catabolic process	4.836438e-6
GO:0033673	negative regulation of kinase activity	4.892141e-6
GO:0045187	regulation of circadian sleep/wake cycle, sleep	4.923954e-6
GO:0007600	sensory perception	4.982258e-6
GO:0007584	response to nutrient	4.991236e-6
GO:0018874	benzoate metabolic process	5.173779e-6
GO:0040014	regulation of multicellular organism growth	5.445251e-6
GO:0007596	blood coagulation	5.519698e-6
GO:0048878	chemical homeostasis	5.565709e-6
GO:0006816	calcium ion transport	5.571714e-6
GO:0050795	regulation of behavior	5.668975e-6
GO:0032878	regulation of establishment or maintenance of cell polarity	6.178407e-6
GO:0007599	hemostasis	6.461408e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	6.643679e-6
GO:0016199	axon midline choice point recognition	6.986936e-6
GO:0045080	positive regulation of chemokine biosynthetic process	7.150959e-6
GO:0001573	ganglioside metabolic process	7.165332e-6
GO:0042035	regulation of cytokine biosynthetic process	7.222373e-6
GO:0007420	brain development	7.658281e-6
GO:0014706	striated muscle tissue development	7.830162e-6
GO:0046824	positive regulation of nucleocytoplasmic transport	7.929497e-6
GO:0016043	cellular component organization	8.064860e-6
GO:0071637	regulation of monocyte chemotactic protein-1 production	8.111499e-6
GO:0032677	regulation of interleukin-8 production	8.462212e-6
GO:0007016	cytoskeletal anchoring at plasma membrane	8.549624e-6
GO:0010574	regulation of vascular endothelial growth factor production	9.358072e-6
GO:0045073	regulation of chemokine biosynthetic process	1.015789e-5
GO:0042542	response to hydrogen peroxide	1.035795e-5
GO:0031668	cellular response to extracellular stimulus	1.064321e-5
GO:0031100	organ regeneration	1.080137e-5
GO:0032496	response to lipopolysaccharide	1.143146e-5
GO:0032386	regulation of intracellular transport	1.256263e-5
GO:0042063	gliogenesis	1.322891e-5
GO:0032770	positive regulation of monooxygenase activity	1.324185e-5
GO:0042742	defense response to bacterium	1.377570e-5
GO:0009593	detection of chemical stimulus	1.413249e-5
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	1.414395e-5
GO:0016198	axon choice point recognition	1.419910e-5
GO:0045409	negative regulation of interleukin-6 biosynthetic process	1.449741e-5
GO:0042753	positive regulation of circadian rhythm	1.458716e-5
GO:0000902	cell morphogenesis	1.549544e-5
GO:0010941	regulation of cell death	1.590955e-5
GO:0048699	generation of neurons	1.653909e-5
GO:0019216	regulation of lipid metabolic process	1.686836e-5
GO:0048520	positive regulation of behavior	1.691704e-5
GO:0007098	centrosome cycle	1.782385e-5
GO:0046785	microtubule polymerization	1.803528e-5
GO:0048631	regulation of skeletal muscle tissue growth	1.807371e-5
GO:0015671	oxygen transport	1.859781e-5
GO:0031929	TOR signaling cascade	1.886043e-5
GO:0002520	immune system development	1.910525e-5
GO:0006469	negative regulation of protein kinase activity	1.932693e-5
GO:0060452	positive regulation of cardiac muscle contraction	1.934262e-5
GO:0045216	cell-cell junction organization	1.944635e-5
GO:0046546	development of primary male sexual characteristics	1.944728e-5
GO:0046322	negative regulation of fatty acid oxidation	1.990534e-5
GO:0002687	positive regulation of leukocyte migration	2.019050e-5
GO:0007601	visual perception	2.061437e-5
GO:0034330	cell junction organization	2.116856e-5
GO:0007616	long-term memory	2.121621e-5
GO:0009966	regulation of signal transduction	2.146587e-5
GO:0055080	cation homeostasis	2.187399e-5
GO:0033523	histone H2B ubiquitination	2.252694e-5
GO:0031669	cellular response to nutrient levels	2.271792e-5
GO:0030193	regulation of blood coagulation	2.279198e-5
GO:0045807	positive regulation of endocytosis	2.390276e-5
GO:0002764	immune response-regulating signaling pathway	2.456335e-5
GO:0021543	pallium development	2.460562e-5
GO:0050953	sensory perception of light stimulus	2.463746e-5
GO:0046622	positive regulation of organ growth	2.536075e-5
GO:0031640	killing of cells of other organism	2.648444e-5
GO:0042036	negative regulation of cytokine biosynthetic process	2.648449e-5
GO:0008207	C21-steroid hormone metabolic process	2.648449e-5
GO:0061041	regulation of wound healing	2.761082e-5
GO:0043549	regulation of kinase activity	2.825549e-5
GO:0045104	intermediate filament cytoskeleton organization	2.865426e-5
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	2.896648e-5
GO:2000191	regulation of fatty acid transport	2.941440e-5
GO:0030162	regulation of proteolysis	2.976024e-5
GO:0040008	regulation of growth	3.083655e-5
GO:0035150	regulation of tube size	3.127249e-5
GO:0002706	regulation of lymphocyte mediated immunity	3.157785e-5
GO:0007567	parturition	3.248911e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	3.273232e-5
GO:0009755	hormone-mediated signaling pathway	3.284640e-5
GO:0030155	regulation of cell adhesion	3.299732e-5
GO:0009267	cellular response to starvation	3.306909e-5
GO:0002437	inflammatory response to antigenic stimulus	3.382470e-5
GO:0045762	positive regulation of adenylate cyclase activity	3.489567e-5
GO:0043407	negative regulation of MAP kinase activity	3.505146e-5
GO:0009581	detection of external stimulus	3.583128e-5
GO:0046849	bone remodeling	3.658653e-5
GO:0002757	immune response-activating signal transduction	3.674976e-5
GO:0031111	negative regulation of microtubule polymerization or depolymerization	3.743376e-5
GO:0048534	hemopoietic or lymphoid organ development	3.771153e-5
GO:0002688	regulation of leukocyte chemotaxis	3.834700e-5
GO:0045597	positive regulation of cell differentiation	3.835703e-5
GO:0007219	Notch signaling pathway	3.904492e-5
GO:0009895	negative regulation of catabolic process	3.951702e-5
GO:0070482	response to oxygen levels	3.988521e-5
GO:0031116	positive regulation of microtubule polymerization	3.995981e-5
GO:0009612	response to mechanical stimulus	4.235438e-5
GO:0045621	positive regulation of lymphocyte differentiation	4.242326e-5
GO:0042981	regulation of apoptosis	4.289866e-5
GO:0046822	regulation of nucleocytoplasmic transport	4.360303e-5
GO:2000097	regulation of smooth muscle cell-matrix adhesion	4.444303e-5
GO:0055009	atrial cardiac muscle tissue morphogenesis	4.454871e-5
GO:0043409	negative regulation of MAPKKK cascade	4.546593e-5
GO:0050880	regulation of blood vessel size	4.603164e-5
GO:0060402	calcium ion transport into cytosol	4.651242e-5
GO:0001101	response to acid	4.681146e-5
GO:0002685	regulation of leukocyte migration	4.711795e-5
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	4.766313e-5
GO:0016056	rhodopsin mediated signaling pathway	4.766313e-5
GO:0030224	monocyte differentiation	4.911366e-5
GO:0050954	sensory perception of mechanical stimulus	5.056241e-5
GO:0031114	regulation of microtubule depolymerization	5.060271e-5
GO:0042127	regulation of cell proliferation	5.258960e-5
GO:0048858	cell projection morphogenesis	5.341937e-5
GO:0043615	astrocyte cell migration	5.386688e-5
GO:0005513	detection of calcium ion	5.399869e-5
GO:0031581	hemidesmosome assembly	5.417045e-5
GO:0034599	cellular response to oxidative stress	5.479227e-5
GO:0030225	macrophage differentiation	5.517663e-5
GO:0021537	telencephalon development	5.684879e-5
GO:0043200	response to amino acid stimulus	5.726173e-5
GO:0010212	response to ionizing radiation	5.746001e-5
GO:0002690	positive regulation of leukocyte chemotaxis	5.751333e-5
GO:0045859	regulation of protein kinase activity	5.757747e-5
GO:0006820	anion transport	5.776875e-5
GO:0001963	synaptic transmission, dopaminergic	5.794863e-5
GO:0051353	positive regulation of oxidoreductase activity	5.820953e-5
GO:0042325	regulation of phosphorylation	5.949792e-5
GO:0008090	retrograde axon cargo transport	6.142922e-5
GO:0051223	regulation of protein transport	6.149688e-5
GO:0031281	positive regulation of cyclase activity	6.176309e-5
GO:0070838	divalent metal ion transport	6.292951e-5
GO:0051349	positive regulation of lyase activity	6.437737e-5
GO:0050818	regulation of coagulation	6.476925e-5
GO:0048669	collateral sprouting in absence of injury	6.498831e-5
GO:0045730	respiratory burst	6.626684e-5
GO:0032768	regulation of monooxygenase activity	6.755023e-5
GO:0010038	response to metal ion	6.988389e-5
GO:0008217	regulation of blood pressure	7.029630e-5
GO:0045428	regulation of nitric oxide biosynthetic process	7.127303e-5
GO:0006817	phosphate ion transport	7.141431e-5
GO:0050878	regulation of body fluid levels	7.207541e-5
GO:0090026	positive regulation of monocyte chemotaxis	7.230969e-5
GO:0021794	thalamus development	7.230969e-5
GO:0021670	lateral ventricle development	7.324538e-5
GO:0032990	cell part morphogenesis	7.454210e-5
GO:0051146	striated muscle cell differentiation	7.512834e-5
GO:0035588	G-protein coupled purinergic receptor signaling pathway	7.559672e-5
GO:0009582	detection of abiotic stimulus	7.621001e-5
GO:0019836	hemolysis by symbiont of host erythrocytes	7.680378e-5
GO:0055098	response to low-density lipoprotein particle stimulus	7.731200e-5
GO:0032790	ribosome disassembly	7.822343e-5
GO:0035684	helper T cell extravasation	7.838547e-5
GO:0031295	T cell costimulation	7.948405e-5
GO:0007409	axonogenesis	8.018738e-5
GO:0051532	regulation of NFAT protein import into nucleus	8.174455e-5
GO:0006586	indolalkylamine metabolic process	8.207005e-5
GO:0071896	protein localization to adherens junction	8.236666e-5
GO:0046661	male sex differentiation	8.483183e-5
GO:0014888	striated muscle adaptation	8.562038e-5
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	9.040096e-5
GO:0071258	cellular response to gravity	9.040096e-5
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	9.040096e-5
GO:0061044	negative regulation of vascular wound healing	9.040096e-5
GO:0022602	ovulation cycle process	9.071557e-5
GO:2000114	regulation of establishment of cell polarity	9.074901e-5
GO:0048260	positive regulation of receptor-mediated endocytosis	9.208908e-5
GO:0032890	regulation of organic acid transport	9.270332e-5
GO:0060326	cell chemotaxis	9.311088e-5
GO:0007026	negative regulation of microtubule depolymerization	9.379063e-5
GO:0043067	regulation of programmed cell death	9.463734e-5

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	6.993657e-21
GO:0055090	acylglycerol homeostasis	4.444869e-19
GO:0002227	innate immune response in mucosa	1.893747e-18
GO:0050896	response to stimulus	3.347527e-18
GO:0006952	defense response	8.900548e-17
GO:0006955	immune response	1.174981e-16
GO:0006982	response to lipid hydroperoxide	3.837682e-16
GO:0006810	transport	2.072272e-14
GO:0002684	positive regulation of immune system process	3.359528e-14
GO:0051234	establishment of localization	7.572162e-14
GO:0002251	organ or tissue specific immune response	2.312049e-13
GO:0006950	response to stress	2.533881e-13
GO:0002385	mucosal immune response	3.884021e-13
GO:0002376	immune system process	9.651746e-13
GO:0050748	negative regulation of lipoprotein metabolic process	1.194090e-11
GO:0034605	cellular response to heat	3.920462e-11
GO:0009611	response to wounding	5.319509e-11
GO:0034372	very-low-density lipoprotein particle remodeling	7.554528e-11
GO:0034370	triglyceride-rich lipoprotein particle remodeling	8.470984e-11
GO:0010627	regulation of intracellular protein kinase cascade	8.636659e-11
GO:0051179	localization	1.002760e-10
GO:0010898	positive regulation of triglyceride catabolic process	1.371532e-10
GO:0051716	cellular response to stimulus	1.570731e-10
GO:0002697	regulation of immune effector process	2.137676e-10
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.177859e-10
GO:0046903	secretion	2.562139e-10
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	2.852011e-10
GO:0050865	regulation of cell activation	9.749256e-10
GO:0050778	positive regulation of immune response	1.194281e-9
GO:0032946	positive regulation of mononuclear cell proliferation	1.284372e-9
GO:0070665	positive regulation of leukocyte proliferation	1.297959e-9
GO:0050776	regulation of immune response	1.529158e-9
GO:0034442	regulation of lipoprotein oxidation	1.585588e-9
GO:0031017	exocrine pancreas development	1.934808e-9
GO:0050671	positive regulation of lymphocyte proliferation	2.108168e-9
GO:0010817	regulation of hormone levels	2.492467e-9
GO:0007154	cell communication	2.746113e-9
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	3.347693e-9
GO:0006629	lipid metabolic process	3.551200e-9
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	3.630420e-9
GO:0023052	signaling	3.894214e-9
GO:0050864	regulation of B cell activation	4.554582e-9
GO:0007254	JNK cascade	5.286482e-9
GO:0043408	regulation of MAPKKK cascade	5.601100e-9
GO:0002694	regulation of leukocyte activation	5.635043e-9
GO:0042060	wound healing	5.839353e-9
GO:0033194	response to hydroperoxide	6.176419e-9
GO:0080134	regulation of response to stress	6.622029e-9
GO:0032940	secretion by cell	7.454261e-9
GO:0002703	regulation of leukocyte mediated immunity	8.354227e-9
GO:0009914	hormone transport	8.521449e-9
GO:0006691	leukotriene metabolic process	1.021090e-8
GO:0048584	positive regulation of response to stimulus	1.092172e-8
GO:0035458	cellular response to interferon-beta	1.280747e-8
GO:0042102	positive regulation of T cell proliferation	1.436716e-8
GO:0031098	stress-activated protein kinase signaling cascade	1.556346e-8
GO:0010832	negative regulation of myotube differentiation	1.582030e-8
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.905878e-8
GO:0002682	regulation of immune system process	2.066047e-8
GO:0007165	signal transduction	2.305257e-8
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.389384e-8
GO:0002706	regulation of lymphocyte mediated immunity	2.982071e-8
GO:0065008	regulation of biological quality	3.002636e-8
GO:0070663	regulation of leukocyte proliferation	3.623362e-8
GO:0001817	regulation of cytokine production	4.946847e-8
GO:0002820	negative regulation of adaptive immune response	5.234331e-8
GO:0042832	defense response to protozoan	5.542866e-8
GO:0032944	regulation of mononuclear cell proliferation	6.918467e-8
GO:0042246	tissue regeneration	7.148301e-8
GO:0050746	regulation of lipoprotein metabolic process	8.197605e-8
GO:0008624	induction of apoptosis by extracellular signals	8.286250e-8
GO:0090208	positive regulation of triglyceride metabolic process	8.291768e-8
GO:0042035	regulation of cytokine biosynthetic process	8.515629e-8
GO:0048583	regulation of response to stimulus	8.856834e-8
GO:0050670	regulation of lymphocyte proliferation	1.032811e-7
GO:0051704	multi-organism process	1.035889e-7
GO:0032814	regulation of natural killer cell activation	1.071680e-7
GO:0050854	regulation of antigen receptor-mediated signaling pathway	1.141537e-7
GO:0061113	pancreas morphogenesis	1.182274e-7
GO:0023061	signal release	1.322710e-7
GO:0002707	negative regulation of lymphocyte mediated immunity	1.704912e-7
GO:0051006	positive regulation of lipoprotein lipase activity	1.985763e-7
GO:0032101	regulation of response to external stimulus	2.203890e-7
GO:0000018	regulation of DNA recombination	2.891450e-7
GO:0042744	hydrogen peroxide catabolic process	2.901882e-7
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.009840e-7
GO:0002268	follicular dendritic cell differentiation	3.756944e-7
GO:0001562	response to protozoan	4.228947e-7
GO:0030300	regulation of intestinal cholesterol absorption	4.778107e-7
GO:0031100	organ regeneration	4.807077e-7
GO:0071702	organic substance transport	5.661195e-7
GO:0051049	regulation of transport	5.962833e-7
GO:0002521	leukocyte differentiation	6.522287e-7
GO:0019370	leukotriene biosynthetic process	6.680327e-7
GO:0001775	cell activation	6.736447e-7
GO:0031099	regeneration	6.776625e-7
GO:0008616	queuosine biosynthetic process	7.824558e-7
GO:0046456	icosanoid biosynthetic process	8.182041e-7
GO:0007159	leukocyte cell-cell adhesion	8.343261e-7
GO:0010740	positive regulation of intracellular protein kinase cascade	8.863639e-7
GO:0007257	activation of JUN kinase activity	9.796197e-7
GO:0000165	MAPKKK cascade	1.172776e-6
GO:0009896	positive regulation of catabolic process	1.225530e-6
GO:0042448	progesterone metabolic process	1.275755e-6
GO:0009266	response to temperature stimulus	1.280674e-6
GO:0043069	negative regulation of programmed cell death	1.340969e-6
GO:0060548	negative regulation of cell death	1.373251e-6
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1.433897e-6
GO:0042108	positive regulation of cytokine biosynthetic process	1.497303e-6
GO:0042327	positive regulation of phosphorylation	1.575006e-6
GO:0007166	cell surface receptor linked signaling pathway	1.659114e-6
GO:0051249	regulation of lymphocyte activation	1.707944e-6
GO:0002698	negative regulation of immune effector process	1.754427e-6
GO:0030431	sleep	1.784960e-6
GO:0035634	response to stilbenoid	1.845537e-6
GO:0009408	response to heat	1.989290e-6
GO:0031347	regulation of defense response	2.015490e-6
GO:0043066	negative regulation of apoptosis	2.228166e-6
GO:0032879	regulation of localization	2.312888e-6
GO:0051707	response to other organism	2.367115e-6
GO:0006954	inflammatory response	2.392939e-6
GO:0010941	regulation of cell death	2.594613e-6
GO:0046879	hormone secretion	2.680798e-6
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	2.910280e-6
GO:0051251	positive regulation of lymphocyte activation	2.949073e-6
GO:0050860	negative regulation of T cell receptor signaling pathway	3.022529e-6
GO:0002921	negative regulation of humoral immune response	3.040096e-6
GO:0002687	positive regulation of leukocyte migration	3.190788e-6
GO:0009607	response to biotic stimulus	3.348820e-6
GO:0043067	regulation of programmed cell death	3.548201e-6
GO:0060157	urinary bladder development	3.566826e-6
GO:0002920	regulation of humoral immune response	3.584193e-6
GO:0032878	regulation of establishment or maintenance of cell polarity	3.647187e-6
GO:0050996	positive regulation of lipid catabolic process	3.713039e-6
GO:0060346	bone trabecula formation	3.756118e-6
GO:0010656	negative regulation of muscle cell apoptosis	3.977070e-6
GO:0006690	icosanoid metabolic process	3.980421e-6
GO:0050867	positive regulation of cell activation	3.994709e-6
GO:0010646	regulation of cell communication	5.074769e-6
GO:0002637	regulation of immunoglobulin production	5.130881e-6
GO:0006636	unsaturated fatty acid biosynthetic process	5.194480e-6
GO:0050856	regulation of T cell receptor signaling pathway	5.288492e-6
GO:0030183	B cell differentiation	5.323656e-6
GO:0032693	negative regulation of interleukin-10 production	5.630243e-6
GO:0040007	growth	6.059320e-6
GO:0019882	antigen processing and presentation	6.087424e-6
GO:0031331	positive regulation of cellular catabolic process	6.093699e-6
GO:0044255	cellular lipid metabolic process	6.111513e-6
GO:0046599	regulation of centriole replication	6.146465e-6
GO:0042981	regulation of apoptosis	6.207318e-6
GO:0042104	positive regulation of activated T cell proliferation	6.399258e-6
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.565306e-6
GO:0051239	regulation of multicellular organismal process	6.658481e-6
GO:0002819	regulation of adaptive immune response	6.680023e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	7.087236e-6
GO:0032102	negative regulation of response to external stimulus	7.220447e-6
GO:0010660	regulation of muscle cell apoptosis	8.283834e-6
GO:0001934	positive regulation of protein phosphorylation	8.694537e-6
GO:0009653	anatomical structure morphogenesis	8.789759e-6
GO:0070327	thyroid hormone transport	8.866028e-6
GO:0002696	positive regulation of leukocyte activation	9.426745e-6
GO:0001944	vasculature development	1.021207e-5
GO:0045910	negative regulation of DNA recombination	1.115142e-5
GO:0046660	female sex differentiation	1.130649e-5
GO:0043269	regulation of ion transport	1.239376e-5
GO:0007612	learning	1.284360e-5
GO:0002709	regulation of T cell mediated immunity	1.308281e-5
GO:0032732	positive regulation of interleukin-1 production	1.362164e-5
GO:0042129	regulation of T cell proliferation	1.399825e-5
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.412355e-5
GO:0010896	regulation of triglyceride catabolic process	1.417761e-5
GO:0051050	positive regulation of transport	1.434876e-5
GO:0046006	regulation of activated T cell proliferation	1.481480e-5
GO:0016579	protein deubiquitination	1.486259e-5
GO:0008617	guanosine metabolic process	1.539863e-5
GO:0009628	response to abiotic stimulus	1.592227e-5
GO:0045796	negative regulation of intestinal cholesterol absorption	1.600579e-5
GO:0010949	negative regulation of intestinal phytosterol absorption	1.600579e-5
GO:0032817	regulation of natural killer cell proliferation	1.610403e-5
GO:0002699	positive regulation of immune effector process	1.651576e-5
GO:0048513	organ development	1.732607e-5
GO:0070328	triglyceride homeostasis	1.735819e-5
GO:0035121	tail morphogenesis	1.735819e-5
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	1.742401e-5
GO:0032731	positive regulation of interleukin-1 beta production	1.768588e-5
GO:0045087	innate immune response	1.791635e-5
GO:0060299	negative regulation of sarcomere organization	1.838728e-5
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.838728e-5
GO:0045937	positive regulation of phosphate metabolic process	1.886831e-5
GO:0000187	activation of MAPK activity	1.892333e-5
GO:0009101	glycoprotein biosynthetic process	1.902083e-5
GO:0015833	peptide transport	1.903395e-5
GO:0043270	positive regulation of ion transport	1.958471e-5
GO:0023051	regulation of signaling	2.078602e-5
GO:0050718	positive regulation of interleukin-1 beta secretion	2.116534e-5
GO:0010824	regulation of centrosome duplication	2.117814e-5
GO:0050830	defense response to Gram-positive bacterium	2.190025e-5
GO:0035964	COPI-coated vesicle budding	2.266584e-5
GO:0015914	phospholipid transport	2.343958e-5
GO:0045191	regulation of isotype switching	2.365552e-5
GO:0044058	regulation of digestive system process	2.400340e-5
GO:0007258	JUN phosphorylation	2.411211e-5
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	2.457689e-5
GO:0051928	positive regulation of calcium ion transport	2.504826e-5
GO:0046425	regulation of JAK-STAT cascade	2.590304e-5
GO:0042325	regulation of phosphorylation	2.593710e-5
GO:0002757	immune response-activating signal transduction	2.662362e-5
GO:0023056	positive regulation of signaling	2.665852e-5
GO:0042221	response to chemical stimulus	2.704575e-5
GO:0042743	hydrogen peroxide metabolic process	2.709036e-5
GO:0001560	regulation of cell growth by extracellular stimulus	2.876268e-5
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	2.890814e-5
GO:0045940	positive regulation of steroid metabolic process	2.981948e-5
GO:0031401	positive regulation of protein modification process	3.042022e-5
GO:0046427	positive regulation of JAK-STAT cascade	3.052523e-5
GO:0060026	convergent extension	3.052879e-5
GO:0046545	development of primary female sexual characteristics	3.140683e-5
GO:0045085	negative regulation of interleukin-2 biosynthetic process	3.169174e-5
GO:0002690	positive regulation of leukocyte chemotaxis	3.174516e-5
GO:0035567	non-canonical Wnt receptor signaling pathway	3.253923e-5
GO:0006631	fatty acid metabolic process	3.456721e-5
GO:0046328	regulation of JNK cascade	3.461373e-5
GO:0043471	regulation of cellular carbohydrate catabolic process	3.517965e-5
GO:0031343	positive regulation of cell killing	3.531776e-5
GO:0010647	positive regulation of cell communication	3.587680e-5
GO:0044240	multicellular organismal lipid catabolic process	3.748937e-5
GO:0051480	cytosolic calcium ion homeostasis	3.767484e-5
GO:0046889	positive regulation of lipid biosynthetic process	3.777030e-5
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	4.000766e-5
GO:0035556	intracellular signal transduction	4.248071e-5
GO:0006916	anti-apoptosis	4.273832e-5
GO:0045577	regulation of B cell differentiation	4.311814e-5
GO:0009956	radial pattern formation	4.367654e-5
GO:0006869	lipid transport	4.464668e-5
GO:0030166	proteoglycan biosynthetic process	4.538615e-5
GO:0042446	hormone biosynthetic process	4.547889e-5
GO:0050851	antigen receptor-mediated signaling pathway	4.675746e-5
GO:0010876	lipid localization	4.913863e-5
GO:0042730	fibrinolysis	4.938322e-5
GO:0006029	proteoglycan metabolic process	5.019429e-5
GO:0060395	SMAD protein signal transduction	5.093801e-5
GO:0043410	positive regulation of MAPKKK cascade	5.241479e-5
GO:0043507	positive regulation of JUN kinase activity	5.286274e-5
GO:0060631	regulation of meiosis I	5.356952e-5
GO:0014904	myotube cell development	5.378791e-5
GO:0071560	cellular response to transforming growth factor beta stimulus	5.521429e-5
GO:0060837	blood vessel endothelial cell differentiation	5.560777e-5
GO:0007204	elevation of cytosolic calcium ion concentration	5.567848e-5
GO:0032816	positive regulation of natural killer cell activation	5.568971e-5
GO:0009966	regulation of signal transduction	5.629230e-5
GO:0002889	regulation of immunoglobulin mediated immune response	5.660717e-5
GO:0002710	negative regulation of T cell mediated immunity	5.705338e-5
GO:0010838	positive regulation of keratinocyte proliferation	5.719697e-5
GO:0002688	regulation of leukocyte chemotaxis	6.046930e-5
GO:0048302	regulation of isotype switching to IgG isotypes	6.061831e-5
GO:0046549	retinal cone cell development	6.148286e-5
GO:0006110	regulation of glycolysis	6.241604e-5
GO:0001909	leukocyte mediated cytotoxicity	6.380978e-5
GO:0002700	regulation of production of molecular mediator of immune response	6.416957e-5
GO:0008643	carbohydrate transport	6.418451e-5
GO:0010676	positive regulation of cellular carbohydrate metabolic process	6.679421e-5
GO:0090179	planar cell polarity pathway involved in neural tube closure	6.921878e-5
GO:0045821	positive regulation of glycolysis	6.921878e-5
GO:0002520	immune system development	6.947835e-5
GO:0050819	negative regulation of coagulation	6.962095e-5
GO:0045591	positive regulation of regulatory T cell differentiation	6.978349e-5
GO:0032621	interleukin-18 production	7.186062e-5
GO:0015939	pantothenate metabolic process	7.186062e-5
GO:0030540	female genitalia development	7.457029e-5
GO:0019220	regulation of phosphate metabolic process	7.483866e-5
GO:0032501	multicellular organismal process	7.496059e-5
GO:0045088	regulation of innate immune response	7.629539e-5
GO:0003008	system process	7.694923e-5
GO:0070302	regulation of stress-activated protein kinase signaling cascade	8.136226e-5
GO:0030098	lymphocyte differentiation	8.248247e-5
GO:0071305	cellular response to vitamin D	8.630607e-5
GO:0010765	positive regulation of sodium ion transport	8.700828e-5
GO:0071391	cellular response to estrogen stimulus	9.224719e-5
GO:0001932	regulation of protein phosphorylation	9.283436e-5
GO:0070875	positive regulation of glycogen metabolic process	9.492855e-5
GO:0032787	monocarboxylic acid metabolic process	9.701156e-5
GO:0042742	defense response to bacterium	9.737018e-5
GO:0002764	immune response-regulating signaling pathway	9.814846e-5
GO:0030097	hemopoiesis	9.929467e-5
GO:0043506	regulation of JUN kinase activity	9.935821e-5
GO:0007267	cell-cell signaling	1.008537e-4
GO:0048608	reproductive structure development	1.098383e-4
GO:0002467	germinal center formation	1.103977e-4
GO:0030104	water homeostasis	1.112105e-4
GO:0042036	negative regulation of cytokine biosynthetic process	1.119773e-4
GO:0006811	ion transport	1.120827e-4
GO:0009100	glycoprotein metabolic process	1.209403e-4
GO:0071559	response to transforming growth factor beta stimulus	1.213704e-4
GO:0055065	metal ion homeostasis	1.224281e-4
GO:0048534	hemopoietic or lymphoid organ development	1.234731e-4
GO:0046885	regulation of hormone biosynthetic process	1.247380e-4
GO:0046967	cytosol to ER transport	1.278478e-4
GO:0019060	intracellular transport of viral proteins in host cell	1.278478e-4
GO:0048293	regulation of isotype switching to IgE isotypes	1.359918e-4
GO:0050777	negative regulation of immune response	1.363204e-4
GO:0034599	cellular response to oxidative stress	1.365384e-4
GO:0031399	regulation of protein modification process	1.393454e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	1.424487e-4
GO:0010738	regulation of protein kinase A signaling cascade	1.428819e-4
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	1.469022e-4
GO:0045321	leukocyte activation	1.469307e-4
GO:0050847	progesterone receptor signaling pathway	1.475567e-4
GO:0002253	activation of immune response	1.508202e-4
GO:2000107	negative regulation of leukocyte apoptosis	1.538203e-4
GO:2000249	regulation of actin cytoskeleton reorganization	1.552009e-4
GO:0018993	somatic sex determination	1.559497e-4
GO:0032648	regulation of interferon-beta production	1.563550e-4
GO:0030262	apoptotic nuclear change	1.565151e-4
GO:0006826	iron ion transport	1.605232e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.616891e-4
GO:0044241	lipid digestion	1.619458e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.641454e-4
GO:0070848	response to growth factor stimulus	1.801064e-4
GO:0050818	regulation of coagulation	1.818502e-4
GO:0010893	positive regulation of steroid biosynthetic process	1.822914e-4
GO:0071392	cellular response to estradiol stimulus	1.834946e-4
GO:0010907	positive regulation of glucose metabolic process	1.854318e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.881928e-4
GO:0046600	negative regulation of centriole replication	1.883976e-4
GO:0050871	positive regulation of B cell activation	1.908388e-4
GO:0014850	response to muscle activity	1.986248e-4
GO:0001819	positive regulation of cytokine production	1.988787e-4
GO:0010520	regulation of reciprocal meiotic recombination	2.070236e-4
GO:0009617	response to bacterium	2.109102e-4
GO:0046928	regulation of neurotransmitter secretion	2.119572e-4
GO:0032680	regulation of tumor necrosis factor production	2.156893e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	2.171503e-4
GO:0060992	response to fungicide	2.181615e-4
GO:0006921	cellular component disassembly involved in apoptosis	2.226971e-4
GO:0009967	positive regulation of signal transduction	2.304115e-4
GO:0071363	cellular response to growth factor stimulus	2.332175e-4
GO:0050870	positive regulation of T cell activation	2.372909e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	2.393896e-4
GO:0060547	negative regulation of necrotic cell death	2.439690e-4
GO:0060741	prostate gland stromal morphogenesis	2.481605e-4
GO:0051096	positive regulation of helicase activity	2.481605e-4
GO:0010524	positive regulation of calcium ion transport into cytosol	2.499108e-4
GO:0031341	regulation of cell killing	2.502188e-4
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	2.526204e-4
GO:0044057	regulation of system process	2.544478e-4
GO:0008210	estrogen metabolic process	2.718271e-4
GO:0001568	blood vessel development	2.728472e-4
GO:0032354	response to follicle-stimulating hormone stimulus	2.817728e-4
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	2.837716e-4
GO:0010033	response to organic substance	2.870800e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	2.883517e-4
GO:0034754	cellular hormone metabolic process	2.928195e-4
GO:0009887	organ morphogenesis	2.930286e-4
GO:0007565	female pregnancy	2.943000e-4
GO:0071900	regulation of protein serine/threonine kinase activity	2.962305e-4
GO:0001906	cell killing	2.988594e-4
GO:0001837	epithelial to mesenchymal transition	2.994105e-4
GO:0002250	adaptive immune response	3.007758e-4
GO:0045073	regulation of chemokine biosynthetic process	3.025204e-4
GO:0042574	retinal metabolic process	3.027951e-4
GO:0001676	long-chain fatty acid metabolic process	3.035149e-4
GO:0009123	nucleoside monophosphate metabolic process	3.056824e-4
GO:0022602	ovulation cycle process	3.105960e-4
GO:0051385	response to mineralocorticoid stimulus	3.189296e-4
GO:0060343	trabecula formation	3.218467e-4
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	3.267431e-4
GO:0032740	positive regulation of interleukin-17 production	3.287989e-4
GO:0009615	response to virus	3.304859e-4
GO:0042698	ovulation cycle	3.357391e-4
GO:2000505	regulation of energy homeostasis	3.399264e-4
GO:0080135	regulation of cellular response to stress	3.449597e-4
GO:0006812	cation transport	3.479252e-4
GO:0001922	B-1 B cell homeostasis	3.550896e-4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	3.575553e-4
GO:0050727	regulation of inflammatory response	3.585212e-4
GO:0048856	anatomical structure development	3.592332e-4
GO:0006813	potassium ion transport	3.633562e-4
GO:0042759	long-chain fatty acid biosynthetic process	3.636549e-4
GO:0043405	regulation of MAP kinase activity	3.653412e-4
GO:0046341	CDP-diacylglycerol metabolic process	3.679447e-4
GO:0002677	negative regulation of chronic inflammatory response	3.679447e-4
GO:0042113	B cell activation	3.853160e-4
GO:0050869	negative regulation of B cell activation	3.866618e-4
GO:0032793	positive regulation of CREB transcription factor activity	3.880082e-4
GO:0002238	response to molecule of fungal origin	4.161764e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	4.224509e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	4.229069e-4
GO:0009306	protein secretion	4.349300e-4
GO:0051095	regulation of helicase activity	4.379547e-4
GO:0014894	response to denervation involved in regulation of muscle adaptation	4.379547e-4
GO:0042703	menstruation	4.461740e-4
GO:0019101	female somatic sex determination	4.461740e-4
GO:0070933	histone H4 deacetylation	4.525096e-4
GO:0035272	exocrine system development	4.551118e-4
GO:0051247	positive regulation of protein metabolic process	4.554753e-4
GO:0032729	positive regulation of interferon-gamma production	4.575468e-4
GO:0051412	response to corticosterone stimulus	4.622841e-4
GO:0072337	modified amino acid transport	4.635869e-4
GO:0046886	positive regulation of hormone biosynthetic process	4.731335e-4
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	4.733179e-4
GO:0022417	protein maturation by protein folding	4.733179e-4
GO:0048731	system development	4.773959e-4
GO:0045089	positive regulation of innate immune response	4.835359e-4
GO:0035644	phosphoanandamide dephosphorylation	4.924017e-4
GO:0072259	metanephric interstitial cell development	4.943858e-4
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	4.943858e-4
GO:0072184	renal vesicle progenitor cell differentiation	4.943858e-4
GO:0072208	metanephric smooth muscle tissue development	4.943858e-4
GO:0006550	isoleucine catabolic process	4.943858e-4
GO:0009098	leucine biosynthetic process	4.943858e-4
GO:0072168	specification of anterior mesonephric tubule identity	4.943858e-4
GO:0072169	specification of posterior mesonephric tubule identity	4.943858e-4
GO:0010959	regulation of metal ion transport	4.983172e-4
GO:0030001	metal ion transport	5.013239e-4
GO:0007167	enzyme linked receptor protein signaling pathway	5.042152e-4
GO:0033003	regulation of mast cell activation	5.096339e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	5.111812e-4
GO:0048294	negative regulation of isotype switching to IgE isotypes	5.130383e-4
GO:0002711	positive regulation of T cell mediated immunity	5.148337e-4
GO:0001839	neural plate morphogenesis	5.269854e-4
GO:0046590	embryonic leg morphogenesis	5.292392e-4
GO:0008635	activation of caspase activity by cytochrome c	5.333456e-4
GO:0045080	positive regulation of chemokine biosynthetic process	5.516283e-4
GO:0065005	protein-lipid complex assembly	5.567085e-4
GO:0001542	ovulation from ovarian follicle	5.567085e-4
GO:0048010	vascular endothelial growth factor receptor signaling pathway	5.685336e-4
GO:0050728	negative regulation of inflammatory response	5.764187e-4
GO:0071346	cellular response to interferon-gamma	5.825804e-4
GO:0051917	regulation of fibrinolysis	5.859150e-4
GO:0009409	response to cold	5.992251e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	6.056572e-4
GO:0060457	negative regulation of digestive system process	6.100178e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	6.100178e-4
GO:0019934	cGMP-mediated signaling	6.311238e-4
GO:0034392	negative regulation of smooth muscle cell apoptosis	6.574894e-4
GO:0015864	pyrimidine nucleoside transport	6.577059e-4
GO:0006198	cAMP catabolic process	6.626139e-4
GO:0043388	positive regulation of DNA binding	6.803465e-4
GO:0048518	positive regulation of biological process	6.850724e-4
GO:0071805	potassium ion transmembrane transport	6.859005e-4
GO:0048519	negative regulation of biological process	6.937999e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.954711e-4
GO:0002685	regulation of leukocyte migration	7.064619e-4
GO:0060164	regulation of timing of neuron differentiation	7.068131e-4
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	7.300852e-4
GO:0007007	inner mitochondrial membrane organization	7.300852e-4
GO:0017156	calcium ion-dependent exocytosis	7.302833e-4
GO:0048514	blood vessel morphogenesis	7.353321e-4
GO:0045911	positive regulation of DNA recombination	7.431418e-4
GO:0030072	peptide hormone secretion	7.793972e-4
GO:0050878	regulation of body fluid levels	7.842373e-4
GO:0055074	calcium ion homeostasis	7.842525e-4
GO:0060926	pacemaker cell development	8.027507e-4
GO:0060932	His-Purkinje system cell differentiation	8.027507e-4
GO:0006875	cellular metal ion homeostasis	8.103208e-4
GO:0070646	protein modification by small protein removal	8.120982e-4
GO:0007596	blood coagulation	8.205881e-4
GO:0019433	triglyceride catabolic process	8.285392e-4
GO:0030850	prostate gland development	8.405702e-4
GO:0090030	regulation of steroid hormone biosynthetic process	8.411808e-4
GO:0045723	positive regulation of fatty acid biosynthetic process	8.497652e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	8.635915e-4
GO:2000507	positive regulation of energy homeostasis	8.731199e-4
GO:2000253	positive regulation of feeding behavior	8.731199e-4
GO:0051289	protein homotetramerization	8.775899e-4
GO:0018904	organic ether metabolic process	8.802991e-4
GO:0060029	convergent extension involved in organogenesis	8.839993e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	8.901491e-4
GO:0032660	regulation of interleukin-17 production	8.935348e-4
GO:0048002	antigen processing and presentation of peptide antigen	9.224688e-4
GO:0048520	positive regulation of behavior	9.232429e-4
GO:0051240	positive regulation of multicellular organismal process	9.286662e-4
GO:0030321	transepithelial chloride transport	9.481108e-4
GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	9.697579e-4
GO:0007599	hemostasis	9.712993e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	9.740855e-4
GO:0048585	negative regulation of response to stimulus	9.788065e-4
GO:0002790	peptide secretion	1.009296e-3
GO:0034391	regulation of smooth muscle cell apoptosis	1.028311e-3
GO:0014070	response to organic cyclic compound	1.047442e-3
GO:0050714	positive regulation of protein secretion	1.054688e-3
GO:0051047	positive regulation of secretion	1.057081e-3
GO:0006801	superoxide metabolic process	1.089200e-3
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.097501e-3
GO:0008626	induction of apoptosis by granzyme	1.097501e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.100123e-3
GO:0046649	lymphocyte activation	1.108448e-3
GO:0045589	regulation of regulatory T cell differentiation	1.116880e-3
GO:0030193	regulation of blood coagulation	1.143059e-3
GO:0045725	positive regulation of glycogen biosynthetic process	1.143759e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.155142e-3
GO:0030518	steroid hormone receptor signaling pathway	1.155175e-3
GO:0043409	negative regulation of MAPKKK cascade	1.167770e-3
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	1.172245e-3
GO:0035630	bone mineralization involved in bone maturation	1.172245e-3
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	1.174184e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	1.174184e-3
GO:0070932	histone H3 deacetylation	1.174184e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.174184e-3
GO:0042445	hormone metabolic process	1.177667e-3