MCL coexpression mm9:230
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0044421 | extracellular region part | 0.0263871369384338 |
| GO:0045625 | regulation of T-helper 1 cell differentiation | 0.0386373874983721 |
| GO:0045627 | positive regulation of T-helper 1 cell differentiation | 0.0386373874983721 |
| GO:0004924 | oncostatin-M receptor activity | 0.0386373874983721 |
| GO:0004896 | hematopoietin/interferon-class (D200-domain) cytokine receptor activity | 0.0386373874983721 |
| GO:0005102 | receptor binding | 0.0386373874983721 |
| GO:0005515 | protein binding | 0.0386373874983721 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0386373874983721 |
| GO:0005578 | proteinaceous extracellular matrix | 0.0386373874983721 |
| GO:0045629 | negative regulation of T-helper 2 cell differentiation | 0.0386373874983721 |
| GO:0045624 | positive regulation of T-helper cell differentiation | 0.0386373874983721 |
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 0.0386373874983721 |
| GO:0007166 | cell surface receptor linked signal transduction | 0.0386373874983721 |
| GO:0009966 | regulation of signal transduction | 0.0386373874983721 |
| GO:0009968 | negative regulation of signal transduction | 0.0386373874983721 |
| GO:0045628 | regulation of T-helper 2 cell differentiation | 0.0386373874983721 |
| GO:0045063 | T-helper 1 cell differentiation | 0.0386373874983721 |
| GO:0017074 | procollagen N-endopeptidase activity | 0.0386373874983721 |
| GO:0045623 | negative regulation of T-helper cell differentiation | 0.0386373874983721 |
| GO:0045064 | T-helper 2 cell differentiation | 0.041147959075257 |
| GO:0008593 | regulation of Notch signaling pathway | 0.041147959075257 |
| GO:0045622 | regulation of T-helper cell differentiation | 0.041147959075257 |
| GO:0007165 | signal transduction | 0.041147959075257 |
| GO:0005615 | extracellular space | 0.041147959075257 |
| GO:0042092 | T-helper 2 type immune response | 0.0476555594886153 |
| GO:0007154 | cell communication | 0.0476555594886153 |
| GO:0050920 | regulation of chemotaxis | 0.0476555594886153 |
| GO:0050926 | regulation of positive chemotaxis | 0.0476555594886153 |
| GO:0050921 | positive regulation of chemotaxis | 0.0476555594886153 |
| GO:0005154 | epidermal growth factor receptor binding | 0.0476555594886153 |
| GO:0050927 | positive regulation of positive chemotaxis | 0.0476555594886153 |
| GO:0050930 | induction of positive chemotaxis | 0.0476555594886153 |
| GO:0002294 | CD4-positive, alpha-beta T cell differentiation during immune response | 0.0476555594886153 |
| GO:0042088 | T-helper 1 type immune response | 0.0476555594886153 |
| GO:0002286 | T cell activation during immune response | 0.0476555594886153 |
| GO:0002292 | T cell differentiation during immune response | 0.0476555594886153 |
| GO:0042093 | T-helper cell differentiation | 0.0476555594886153 |
| GO:0019894 | kinesin binding | 0.0476555594886153 |
| GO:0002285 | lymphocyte activation during immune response | 0.0476555594886153 |
| GO:0002293 | alpha-beta T cell differentiation during immune response | 0.0476555594886153 |
| GO:0050918 | positive chemotaxis | 0.0476555594886153 |
| GO:0051605 | protein maturation via proteolysis | 0.0499379591277511 |
| GO:0002366 | leukocyte activation during immune response | 0.0499379591277511 |
| GO:0002263 | cell activation during immune response | 0.0499379591277511 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
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