MCL coexpression mm9:260

Phase1 CAGE Peaks

	Short description
Mm9::chr10:59837508..59837512,+	p@chr10:59837508..59837512 +
Mm9::chr10:61969030..61969043,-	p@chr10:61969030..61969043 -
Mm9::chr11:70464139..70464152,+	p@chr11:70464139..70464152 +
Mm9::chr11:82877968..82877973,+	p@chr11:82877968..82877973 +
Mm9::chr11:82877992..82878000,+	p@chr11:82877992..82878000 +
Mm9::chr15:78402228..78402241,+	p@chr15:78402228..78402241 +
Mm9::chr17:21587400..21587411,+	p@chr17:21587400..21587411 +
Mm9::chr17:35399747..35399768,+	p3@H2-D1
Mm9::chr1:163001536..163001548,-	p@chr1:163001536..163001548 -
Mm9::chr1:58770164..58770176,+	p4@Cflar
Mm9::chr1:92949614..92949625,-	p@chr1:92949614..92949625 -
Mm9::chr1:92950423..92950427,-	p@chr1:92950423..92950427 -
Mm9::chr1:92950550..92950569,+	p@chr1:92950550..92950569 +
Mm9::chr1:92953199..92953213,+	p@chr1:92953199..92953213 +
Mm9::chr1:92953250..92953273,+	p@chr1:92953250..92953273 +
Mm9::chr1:92954465..92954475,+	p@chr1:92954465..92954475 +
Mm9::chr2:73301971..73301982,-	p@chr2:73301971..73301982 -
Mm9::chr2:73323739..73323761,-	p12@Wipf1
Mm9::chr2:94278218..94278232,-	p2@Api5
Mm9::chr4:8840833..8840836,-	p@chr4:8840833..8840836 -
Mm9::chr5:108155037..108155060,-	p2@Gfi1
Mm9::chr5:32000704..32000714,-	p@chr5:32000704..32000714 -
Mm9::chr5:32436063..32436081,+	p@chr5:32436063..32436081 +
Mm9::chr5:32436178..32436190,+	p@chr5:32436178..32436190 +
Mm9::chr7:109398056..109398073,-	p@chr7:109398056..109398073 -
Mm9::chr7:31203177..31203188,+	p@chr7:31203177..31203188 +
Mm9::chr7:31204934..31204968,+	p@chr7:31204934..31204968 +
Mm9::chr7:31205383..31205392,-	p@chr7:31205383..31205392 -
Mm9::chr7:31206627..31206655,-	p@chr7:31206627..31206655 -
Mm9::chr8:129376078..129376081,-	p@chr8:129376078..129376081 -
Mm9::chr8:85856266..85856269,-	p3@Elmod2
Mm9::chr9:66767453..66767517,-	p1@Rab8b

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042660	positive regulation of cell fate specification	0.0327773654156251
GO:0042659	regulation of cell fate specification	0.0327773654156251
GO:0010453	regulation of cell fate commitment	0.0327773654156251
GO:0009996	negative regulation of cell fate specification	0.0327773654156251
GO:0010454	negative regulation of cell fate commitment	0.0327773654156251
GO:0043154	negative regulation of caspase activity	0.0382809443418322
GO:0007638	mechanosensory behavior	0.0382809443418322
GO:0043066	negative regulation of apoptosis	0.0382809443418322
GO:0043069	negative regulation of programmed cell death	0.0382809443418322
GO:0005522	profilin binding	0.0491283492655764

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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