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MCL coexpression mm9:724

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:118391138..118391145,+p4@Hcn1
Mm9::chr17:93598348..93598373,+p3@Adcyap1
Mm9::chr3:34459134..34459146,+p1@ENSMUST00000172935
Mm9::chr3:34459266..34459272,+p4@ENSMUST00000172935
Mm9::chr3:34459282..34459308,+p1@Sox2ot
Mm9::chr3:34459548..34459568,+p@chr3:34459548..34459568
+
Mm9::chr5:82229760..82229765,+p@chr5:82229760..82229765
+
Mm9::chr9:75445450..75445463,-p8@Tmod2
Mm9::chr9:75445481..75445519,-p6@Tmod2
Mm9::chr9:75445524..75445545,-p9@Tmod2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045745positive regulation of G-protein coupled receptor protein signaling pathway0.0239826601982353
GO:0005523tropomyosin binding0.0239826601982353
GO:0045176apical protein localization0.0239826601982353
GO:0008105asymmetric protein localization0.0239826601982353
GO:0030552cAMP binding0.0239826601982353
GO:0007190adenylate cyclase activation0.0239826601982353
GO:0031281positive regulation of cyclase activity0.0239826601982353
GO:0051349positive regulation of lyase activity0.0239826601982353
GO:0045762positive regulation of adenylate cyclase activity0.0239826601982353
GO:0016208AMP binding0.0239826601982353
GO:0045761regulation of adenylate cyclase activity0.0239826601982353
GO:0031279regulation of cyclase activity0.0239826601982353
GO:0008277regulation of G-protein coupled receptor protein signaling pathway0.0239826601982353
GO:0051339regulation of lyase activity0.0239826601982353
GO:0005184neuropeptide hormone activity0.0239826601982353
GO:0030551cyclic nucleotide binding0.0239826601982353
GO:0007270nerve-nerve synaptic transmission0.0285040806208462
GO:0005272sodium channel activity0.029160700324735
GO:0007189G-protein signaling, adenylate cyclase activating pathway0.0371704040420905
GO:0030425dendrite0.0483932198836574



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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