Personal tools

MCL coexpression mm9:2357

From FANTOM5_SSTAR

Revision as of 11:35, 11 October 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Phase1 CAGE Peaks

 Short description
Mm9::chr3:106903846..106903907,+p@chr3:106903846..106903907
+
Mm9::chr5:138404139..138404159,-p2@Gjc3
Mm9::chr9:48910825..48910857,+p1@Tmprss5
Mm9::chr9:48916767..48916770,+p2@Tmprss5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0043209myelin sheath0.0215202749941214
GO:0005243gap junction channel activity0.0215202749941214
GO:0022829wide pore channel activity0.0215202749941214
GO:0005922connexon complex0.0215202749941214
GO:0005044scavenger receptor activity0.0215202749941214
GO:0005921gap junction0.0215202749941214
GO:0042552myelination0.0215202749941214
GO:0008366axon ensheathment0.0215202749941214
GO:0007272ensheathment of neurons0.0215202749941214
GO:0001508regulation of action potential0.0247057926010595
GO:0014704intercalated disc0.0273099945861852
GO:0007605sensory perception of sound0.049740520502399
GO:0050954sensory perception of mechanical stimulus0.049740520502399



Relative expression of the co-expression cluster over median <br>Analyst:



"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}