MCL coexpression mm9:1425
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr1:173934582..173934589,- | p@chr1:173934582..173934589 - |
| Mm9::chr1:173934659..173934666,- | p@chr1:173934659..173934666 - |
| Mm9::chr1:173934671..173934684,- | p@chr1:173934671..173934684 - |
| Mm9::chr1:173957382..173957399,- | p2@Vangl2 |
| Mm9::chr1:173957400..173957444,- | p1@Vangl2 |
| Mm9::chr1:173987720..173987729,- | p1@Nhlh1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0035058 | sensory cilium biogenesis | 0.0137063192827999 |
| GO:0007164 | establishment of tissue polarity | 0.0137063192827999 |
| GO:0001736 | establishment of planar polarity | 0.0137063192827999 |
| GO:0045197 | establishment and/or maintenance of epithelial cell polarity | 0.0137063192827999 |
| GO:0045176 | apical protein localization | 0.0137063192827999 |
| GO:0008105 | asymmetric protein localization | 0.0137063192827999 |
| GO:0035088 | establishment and/or maintenance of apical/basal cell polarity | 0.0137063192827999 |
| GO:0001738 | morphogenesis of a polarized epithelium | 0.0137063192827999 |
| GO:0042384 | cilium biogenesis | 0.0139543778698986 |
| GO:0001947 | heart looping | 0.0139543778698986 |
| GO:0007163 | establishment and/or maintenance of cell polarity | 0.0217411228203974 |
| GO:0003007 | heart morphogenesis | 0.0282255244932613 |
| GO:0001843 | neural tube closure | 0.028373652194394 |
| GO:0014020 | primary neural tube formation | 0.028373652194394 |
| GO:0030031 | cell projection biogenesis | 0.028373652194394 |
| GO:0016324 | apical plasma membrane | 0.028373652194394 |
| GO:0001841 | neural tube formation | 0.028373652194394 |
| GO:0001839 | neural plate morphogenesis | 0.028373652194394 |
| GO:0001840 | neural plate development | 0.028373652194394 |
| GO:0001838 | embryonic epithelial tube formation | 0.028373652194394 |
| GO:0021915 | neural tube development | 0.0308083974695856 |
| GO:0016331 | morphogenesis of embryonic epithelium | 0.0330202130454143 |
| GO:0045177 | apical part of cell | 0.0333115541741164 |
| GO:0002009 | morphogenesis of an epithelium | 0.0495929248956148 |
| GO:0007275 | multicellular organismal development | 0.0495929248956148 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| ectodermal cell | 3.18e-12 | 44 |
| neurectodermal cell | 3.18e-12 | 44 |
| neural cell | 1.16e-11 | 43 |
| neuron | 2.94e-11 | 33 |
| neuronal stem cell | 2.94e-11 | 33 |
| neuroblast | 2.94e-11 | 33 |
| electrically signaling cell | 2.94e-11 | 33 |
| CNS neuron (sensu Vertebrata) | 3.18e-11 | 23 |
| neuroblast (sensu Vertebrata) | 3.18e-11 | 23 |
| non-terminally differentiated cell | 1.99e-09 | 49 |
| electrically responsive cell | 1.10e-08 | 39 |
| electrically active cell | 1.10e-08 | 39 |
| Ontology term | p-value | n |
|---|---|---|
| ectoderm-derived structure | 1.79e-15 | 95 |
| ectoderm | 1.79e-15 | 95 |
| presumptive ectoderm | 1.79e-15 | 95 |
| ecto-epithelium | 1.44e-14 | 73 |
| central nervous system | 6.25e-12 | 73 |
| neurectoderm | 6.42e-12 | 64 |
| neural plate | 6.42e-12 | 64 |
| presumptive neural plate | 6.42e-12 | 64 |
| multi-cellular organism | 9.94e-12 | 333 |
| embryo | 1.38e-11 | 320 |
| nervous system | 5.35e-11 | 75 |
| structure with developmental contribution from neural crest | 3.34e-09 | 92 |
| neural tube | 8.90e-09 | 52 |
| neural rod | 8.90e-09 | 52 |
| future spinal cord | 8.90e-09 | 52 |
| neural keel | 8.90e-09 | 52 |
| pre-chordal neural plate | 1.19e-08 | 49 |
| regional part of nervous system | 1.28e-08 | 54 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 2.22936 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 0.52077 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 0.304529 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 0.370592 |
| MA0029.1 | 0.920529 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 2.01886 |
| MA0042.1 | 1.97265 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 2.15574 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 1.00829 |
| MA0055.1 | 0.465302 |
| MA0056.1 | 0 |
| MA0057.1 | 2.76847 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 0.449345 |
| MA0060.1 | 1.38604 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 0.467569 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 0.575909 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 0.972762 |
| MA0074.1 | 0.638014 |
| MA0076.1 | 0.407465 |
| MA0077.1 | 2.22096 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 2.07288 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 0.358337 |
| MA0089.1 | 0 |
| MA0090.1 | 3.19482 |
| MA0091.1 | 0.55008 |
| MA0092.1 | 1.25163 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.626021 |
| MA0101.1 | 1.16089 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 1.09694 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 1.0169 |
| MA0108.2 | 0.824407 |
| MA0109.1 | 0 |
| MA0111.1 | 1.2824 |
| MA0113.1 | 0.708789 |
| MA0114.1 | 0.822296 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.944657 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 0.459301 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 2.74529 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 0.419361 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.829535 |
| MA0145.1 | 0.761789 |
| MA0146.1 | 0.635245 |
| MA0147.1 | 0.320675 |
| MA0148.1 | 0.553294 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 0.204999 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 1.39094 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.246463 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.261255 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.37938 |
| MA0065.2 | 1.81707 |
| MA0150.1 | 0.520653 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.480757 |
| MA0155.1 | 1.92909 |
| MA0156.1 | 0.406559 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 1.58527 |
| MA0160.1 | 0.556423 |
| MA0161.1 | 0 |
| MA0162.1 | 0.397553 |
| MA0163.1 | 8.27119 |
| MA0164.1 | 0.658997 |
| MA0080.2 | 1.01893 |
| MA0018.2 | 0.669032 |
| MA0099.2 | 0.781628 |
| MA0079.2 | 7.21796 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.309517 |
| MA0442.1 | 0 |
