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MCL coexpression mm9:423

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:116715066..116715150,+p1@Mfsd11
Mm9::chr12:103677954..103677968,-p3@Lgmn
Mm9::chr12:8320231..8320260,+p1@Hs1bp3
Mm9::chr15:89004361..89004407,-p3@Plxnb2
Mm9::chr2:164659281..164659312,+p1@Ctsa
Mm9::chr2:25211839..25211886,-p1@Dpp7
Mm9::chr3:53267122..53267154,-p2@Nhlrc3
Mm9::chr3:53267156..53267228,-p1@Nhlrc3
Mm9::chr3:88128952..88128997,+p1@0610031J06Rik
Mm9::chr5:30950308..30950371,+p1@4930471M23Rik
Mm9::chr5:31210065..31210126,-p1@Gm19774
p1@Ost4
Mm9::chr5:37221812..37221885,-p1@Man2b2
Mm9::chr5:37221886..37221896,-p2@Man2b2
Mm9::chr7:112900707..112900748,-p1@Tpp1
Mm9::chr8:87607168..87607196,+p2@Man2b1
Mm9::chr8:98377401..98377430,-p1@Slc38a7
Mm9::chr9:106587656..106587694,-p2@Tex264
Mm9::chr9:106587698..106587716,-p10@Tex264


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005764lysosome3.9790322658491e-08
GO:0000323lytic vacuole3.9790322658491e-08
GO:0005773vacuole5.35678442454625e-08
GO:0004559alpha-mannosidase activity0.00022402824154555
GO:0006013mannose metabolic process0.000536882639692648
GO:0008238exopeptidase activity0.000708081257451535
GO:0015923mannosidase activity0.000774364732215079
GO:0004177aminopeptidase activity0.00394371374385564
GO:0017171serine hydrolase activity0.00394371374385564
GO:0008236serine-type peptidase activity0.00394371374385564
GO:0006508proteolysis0.00660720370132939
GO:0004186carboxypeptidase C activity0.00680771686289669
GO:0019131tripeptidyl-peptidase I activity0.00680771686289669
GO:0043171peptide catabolic process0.00680771686289669
GO:0008233peptidase activity0.00680771686289669
GO:0016787hydrolase activity0.00908076867295631
GO:0008240tripeptidyl-peptidase activity0.0110268265042963
GO:0001509legumain activity0.0110268265042963
GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds0.011419743294679
GO:0016798hydrolase activity, acting on glycosyl bonds0.0162810385064759
GO:0004175endopeptidase activity0.0162810385064759
GO:0004185serine carboxypeptidase activity0.0180330260152798
GO:0019318hexose metabolic process0.0203214838823665
GO:0045862positive regulation of proteolysis0.0203214838823665
GO:0005996monosaccharide metabolic process0.0203214838823665
GO:0040015negative regulation of multicellular organism growth0.0324324902690303
GO:0006518peptide metabolic process0.0324324902690303
GO:0005615extracellular space0.0324324902690303
GO:0004252serine-type endopeptidase activity0.033188059845617
GO:0044421extracellular region part0.0382839822925629
GO:0050772positive regulation of axonogenesis0.0382839822925629
GO:0044444cytoplasmic part0.0382839822925629
GO:0030162regulation of proteolysis0.0389657680671849
GO:0004289subtilase activity0.0400757626685785
GO:0007040lysosome organization and biogenesis0.0400757626685785
GO:0045453bone resorption0.0400757626685785
GO:0050769positive regulation of neurogenesis0.0400757626685785
GO:0044262cellular carbohydrate metabolic process0.0440792899334869
GO:0006066alcohol metabolic process0.0449581600631616
GO:0007033vacuole organization and biogenesis0.0468989193720354



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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