MCL coexpression mm9:1421

Phase1 CAGE Peaks

	Short description
Mm9::chr19:61216675..61216726,-	p1@ENSMUST00000122927 p1@ENSMUST00000127117 p1@ENSMUST00000143264 p1@uc008icf.2 p1@uc008icg.2 p1@uc008ici.1
Mm9::chr4:62021470..62021545,-	p1@Fkbp15
Mm9::chr4:73897832..73897894,+	p1@Kdm4c
Mm9::chr5:110295720..110295766,+	p@chr5:110295720..110295766 +
Mm9::chr8:93593951..93594022,+	p1@Rbl2
Mm9::chrX:20639107..20639188,-	p1@Zfp182

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016568	chromatin modification	0.0278390932588522
GO:0006325	establishment and/or maintenance of chromatin architecture	0.0278390932588522
GO:0006323	DNA packaging	0.0278390932588522
GO:0051276	chromosome organization and biogenesis	0.0278390932588522
GO:0030426	growth cone	0.0278390932588522
GO:0030427	site of polarized growth	0.0278390932588522
GO:0006355	regulation of transcription, DNA-dependent	0.0278390932588522
GO:0006351	transcription, DNA-dependent	0.0278390932588522
GO:0032774	RNA biosynthetic process	0.0278390932588522
GO:0003677	DNA binding	0.0278390932588522
GO:0045449	regulation of transcription	0.0278390932588522
GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0278390932588522
GO:0006350	transcription	0.0278390932588522
GO:0010468	regulation of gene expression	0.0278390932588522
GO:0005884	actin filament	0.0278390932588522
GO:0031323	regulation of cellular metabolic process	0.0281658112945624
GO:0019222	regulation of metabolic process	0.0284271100944954
GO:0006259	DNA metabolic process	0.0284271100944954
GO:0016070	RNA metabolic process	0.0284271100944954
GO:0043170	macromolecule metabolic process	0.0300812145158244
GO:0010467	gene expression	0.0400737164773372
GO:0003676	nucleic acid binding	0.0400737164773372
GO:0044238	primary metabolic process	0.0400737164773372
GO:0051213	dioxygenase activity	0.0400737164773372
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.0400737164773372
GO:0044237	cellular metabolic process	0.0400737164773372
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.0400737164773372
GO:0030424	axon	0.0400737164773372
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0415391950259398
GO:0050794	regulation of cellular process	0.0490363897477721

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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