MCL coexpression mm9:2652

Phase1 CAGE Peaks

	Short description
Mm9::chr11:20101409..20101451,+	p1@Rab1
Mm9::chr18:46757134..46757197,-	p1@Tmed7
Mm9::chrX:35988272..35988325,-	p1@C1galt1c1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008565	protein transporter activity	0.014370948810832
GO:0006886	intracellular protein transport	0.0307922319741016
GO:0000160	two-component signal transduction system (phosphorelay)	0.0307922319741016
GO:0006888	ER to Golgi vesicle-mediated transport	0.0307922319741016
GO:0046907	intracellular transport	0.0307922319741016
GO:0008320	protein transmembrane transporter activity	0.0307922319741016
GO:0015031	protein transport	0.0307922319741016
GO:0045184	establishment of protein localization	0.0307922319741016
GO:0008104	protein localization	0.0307922319741016
GO:0051649	establishment of cellular localization	0.0307922319741016
GO:0051641	cellular localization	0.0307922319741016
GO:0033036	macromolecule localization	0.0307922319741016
GO:0048193	Golgi vesicle transport	0.0378768306360005
GO:0022892	substrate-specific transporter activity	0.0402874153624857

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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