MCL coexpression mm9:165
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0045579 | positive regulation of B cell differentiation | 0.0229382452089853 |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 0.0229382452089853 |
| GO:0007242 | intracellular signaling cascade | 0.025854791355854 |
| GO:0045577 | regulation of B cell differentiation | 0.025854791355854 |
| GO:0045621 | positive regulation of lymphocyte differentiation | 0.0357557661754232 |
| GO:0032943 | mononuclear cell proliferation | 0.0357557661754232 |
| GO:0046651 | lymphocyte proliferation | 0.0357557661754232 |
| GO:0002376 | immune system process | 0.0357557661754232 |
| GO:0046649 | lymphocyte activation | 0.0357557661754232 |
| GO:0051249 | regulation of lymphocyte activation | 0.0357557661754232 |
| GO:0005737 | cytoplasm | 0.0357557661754232 |
| GO:0050865 | regulation of cell activation | 0.0357557661754232 |
| GO:0045321 | leukocyte activation | 0.0357557661754232 |
| GO:0030097 | hemopoiesis | 0.0357557661754232 |
| GO:0030099 | myeloid cell differentiation | 0.0357557661754232 |
| GO:0045619 | regulation of lymphocyte differentiation | 0.0357557661754232 |
| GO:0001775 | cell activation | 0.0357557661754232 |
| GO:0050871 | positive regulation of B cell activation | 0.0357557661754232 |
| GO:0048534 | hemopoietic or lymphoid organ development | 0.0357557661754232 |
| GO:0002520 | immune system development | 0.0357557661754232 |
| GO:0008375 | acetylglucosaminyltransferase activity | 0.0357557661754232 |
| GO:0042110 | T cell activation | 0.0357557661754232 |
| GO:0045588 | positive regulation of gamma-delta T cell differentiation | 0.0357557661754232 |
| GO:0046643 | regulation of gamma-delta T cell activation | 0.0357557661754232 |
| GO:0030686 | 90S preribosome | 0.0357557661754232 |
| GO:0030690 | Noc1p-Noc2p complex | 0.0357557661754232 |
| GO:0046645 | positive regulation of gamma-delta T cell activation | 0.0357557661754232 |
| GO:0045659 | negative regulation of neutrophil differentiation | 0.0357557661754232 |
| GO:0045586 | regulation of gamma-delta T cell differentiation | 0.0357557661754232 |
| GO:0030171 | voltage-gated proton channel activity | 0.0357557661754232 |
| GO:0045658 | regulation of neutrophil differentiation | 0.0357557661754232 |
| GO:0005521 | lamin binding | 0.0357557661754232 |
| GO:0030852 | regulation of granulocyte differentiation | 0.0357557661754232 |
| GO:0030687 | nucleolar preribosome, large subunit precursor | 0.0357557661754232 |
| GO:0030853 | negative regulation of granulocyte differentiation | 0.0357557661754232 |
| GO:0045409 | negative regulation of interleukin-6 biosynthetic process | 0.0357557661754232 |
| GO:0000334 | 3-hydroxyanthranilate 3,4-dioxygenase activity | 0.0357557661754232 |
| GO:0030689 | Noc complex | 0.0357557661754232 |
| GO:0045656 | negative regulation of monocyte differentiation | 0.0357557661754232 |
| GO:0045655 | regulation of monocyte differentiation | 0.0357557661754232 |
| GO:0002521 | leukocyte differentiation | 0.0389229665753655 |
| GO:0030183 | B cell differentiation | 0.0393318142679435 |
| GO:0050864 | regulation of B cell activation | 0.0428888017035016 |
| GO:0002573 | myeloid leukocyte differentiation | 0.0488960027584729 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
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