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MCL coexpression mm9:248

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:81091291..81091312,+p7@Ankrd24
Mm9::chr11:75751179..75751224,-p2@Rph3al
Mm9::chr11:97213662..97213677,-p1@Gpr179
Mm9::chr12:74040716..74040745,+p3@Six6
Mm9::chr13:98517328..98517339,-p1@ENSMUST00000123535
Mm9::chr13:98517354..98517369,-p1@ENSMUST00000144993
p1@uc007rof.1
p1@uc007rog.1
Mm9::chr14:18814327..18814334,+p10@Thrb
Mm9::chr14:18814381..18814390,+p7@Thrb
Mm9::chr14:18814402..18814414,+p@chr14:18814402..18814414
+
Mm9::chr16:65520838..65520853,+p1@Pou1f1
Mm9::chr16:65523642..65523649,+p3@Pou1f1
Mm9::chr17:52741567..52741609,+p2@Kcnh8
Mm9::chr17:52741610..52741620,+p6@Kcnh8
Mm9::chr17:56381175..56381209,+p1@uc008dbj.1
Mm9::chr1:167090803..167090816,-p1@Tbx19
Mm9::chr1:167090905..167090912,-p2@Tbx19
Mm9::chr1:167090920..167090924,-p3@Tbx19
Mm9::chr1:74947550..74947553,-p@chr1:74947550..74947553
-
Mm9::chr1:75438947..75438964,+p@chr1:75438947..75438964
+
Mm9::chr2:157366618..157366640,-p@chr2:157366618..157366640
-
Mm9::chr2:174153248..174153264,+p2@Gnas
Mm9::chr2:174154863..174154912,+p@chr2:174154863..174154912
+
Mm9::chr2:26062195..26062206,+p@chr2:26062195..26062206
+
Mm9::chr2:26063801..26063813,-p2@Lhx3
Mm9::chr3:102586593..102586598,-p1@Tshb
Mm9::chr3:102586631..102586638,-p2@Tshb
Mm9::chr5:117863775..117863794,+p4@Ksr2
Mm9::chr5:117863819..117863831,+p8@Ksr2
Mm9::chr6:99619574..99619589,-p@chr6:99619574..99619589
-
Mm9::chr7:52910997..52911006,-p@chr7:52910997..52911006
-
Mm9::chr7:52911010..52911020,-p@chr7:52911010..52911020
-
Mm9::chr7:52911023..52911037,-p@chr7:52911023..52911037
-
Mm9::chr7:86033242..86033245,+p1@Mir7-2
Mm9::chrX:47150877..47150932,-p1@Igsf1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0050794regulation of cellular process0.00590710375771117
GO:0050789regulation of biological process0.00590710375771117
GO:0021983pituitary gland development0.00590710375771117
GO:0021536diencephalon development0.00590710375771117
GO:0065007biological regulation0.00590710375771117
GO:0003700transcription factor activity0.00590710375771117
GO:0043565sequence-specific DNA binding0.00642647008083665
GO:0045944positive regulation of transcription from RNA polymerase II promoter0.0112185472859472
GO:0007417central nervous system development0.0112364024618341
GO:0045893positive regulation of transcription, DNA-dependent0.0112364024618341
GO:0035270endocrine system development0.0112364024618341
GO:0006355regulation of transcription, DNA-dependent0.0112364024618341
GO:0006351transcription, DNA-dependent0.0112364024618341
GO:0032774RNA biosynthetic process0.0112364024618341
GO:0045449regulation of transcription0.0112364024618341
GO:0032962positive regulation of inositol trisphosphate biosynthetic process0.0112364024618341
GO:0040032post-embryonic body morphogenesis0.0112364024618341
GO:0032958inositol phosphate biosynthetic process0.0112364024618341
GO:0032960regulation of inositol trisphosphate biosynthetic process0.0112364024618341
GO:0032959inositol trisphosphate biosynthetic process0.0112364024618341
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0112364024618341
GO:0045941positive regulation of transcription0.0112364024618341
GO:0006350transcription0.0112364024618341
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0112364024618341
GO:0010468regulation of gene expression0.0124911522910315
GO:0048522positive regulation of cellular process0.0124911522910315
GO:0048732gland development0.0128309556366026
GO:0031323regulation of cellular metabolic process0.0128309556366026
GO:0009966regulation of signal transduction0.0128309556366026
GO:0007275multicellular organismal development0.0128309556366026
GO:0021526medial motor column neuron differentiation0.0128309556366026
GO:0006021inositol biosynthetic process0.0128309556366026
GO:0043647inositol phosphate metabolic process0.0128309556366026
GO:0032957inositol trisphosphate metabolic process0.0128309556366026
GO:0060133somatotropin secreting cell development0.0128309556366026
GO:0019222regulation of metabolic process0.0128309556366026
GO:0031325positive regulation of cellular metabolic process0.0128309556366026
GO:0016070RNA metabolic process0.0138703516458522
GO:0009893positive regulation of metabolic process0.0138703516458522
GO:0048518positive regulation of biological process0.0138703516458522
GO:0006357regulation of transcription from RNA polymerase II promoter0.0147857581625108
GO:0030900forebrain development0.0148460829282235
GO:0045165cell fate commitment0.0148460829282235
GO:0060126somatotropin secreting cell differentiation0.0148460829282235
GO:0021523somatic motor neuron differentiation0.0148460829282235
GO:0004887thyroid hormone receptor activity0.0148460829282235
GO:0043567regulation of insulin-like growth factor receptor signaling pathway0.0148460829282235
GO:0005667transcription factor complex0.0164725702998602
GO:0006366transcription from RNA polymerase II promoter0.0165816177594602
GO:0017158regulation of calcium ion-dependent exocytosis0.0172982678649299
GO:0045913positive regulation of carbohydrate metabolic process0.0172982678649299
GO:0045672positive regulation of osteoclast differentiation0.0172982678649299
GO:0043255regulation of carbohydrate biosynthetic process0.0172982678649299
GO:0048731system development0.0172982678649299
GO:0002521leukocyte differentiation0.0194933648973085
GO:0000155two-component sensor activity0.0202358494253453
GO:0010171body morphogenesis0.0202358494253453
GO:0019899enzyme binding0.0202358494253453
GO:0005515protein binding0.0211253157868178
GO:0010467gene expression0.0211253157868178
GO:0021984adenohypophysis development0.0211253157868178
GO:0006109regulation of carbohydrate metabolic process0.0211253157868178
GO:0021522spinal cord motor neuron differentiation0.0211253157868178
GO:0048701embryonic cranial skeleton morphogenesis0.0211253157868178
GO:0002763positive regulation of myeloid leukocyte differentiation0.0211253157868178
GO:0021517ventral spinal cord development0.0211253157868178
GO:0044451nucleoplasm part0.0221721459452071
GO:0003677DNA binding0.0222761548361811
GO:0045744negative regulation of G-protein coupled receptor protein signaling pathway0.0222761548361811
GO:0008340determination of adult life span0.0222761548361811
GO:0045669positive regulation of osteoblast differentiation0.0222761548361811
GO:0007191dopamine receptor, adenylate cyclase activating pathway0.0222761548361811
GO:0021515cell differentiation in spinal cord0.0222761548361811
GO:0005654nucleoplasm0.0228968227183673
GO:0048856anatomical structure development0.0238193328862061
GO:0032502developmental process0.0238193328862061
GO:0009886post-embryonic morphogenesis0.0238193328862061
GO:0001958endochondral ossification0.0238193328862061
GO:0000160two-component signal transduction system (phosphorelay)0.0254819134731916
GO:0008045motor axon guidance0.0254819134731916
GO:0048009insulin-like growth factor receptor signaling pathway0.0254819134731916
GO:0006020inositol metabolic process0.0254819134731916
GO:0007420brain development0.026621305295221
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0269882116123206
GO:0004673protein histidine kinase activity0.0269882116123206
GO:0010259multicellular organismal aging0.0269882116123206
GO:0007399nervous system development0.0275084067601556
GO:0048704embryonic skeletal morphogenesis0.029003590036877
GO:0031981nuclear lumen0.0307770382413672
GO:0045667regulation of osteoblast differentiation0.0307770382413672
GO:0030097hemopoiesis0.0307770382413672
GO:0048513organ development0.0320697550064008
GO:0045639positive regulation of myeloid cell differentiation0.0320697550064008
GO:0021510spinal cord development0.0320697550064008
GO:0035116embryonic hindlimb morphogenesis0.0338069629820718
GO:0016775phosphotransferase activity, nitrogenous group as acceptor0.0338069629820718
GO:0048534hemopoietic or lymphoid organ development0.0354718434540506
GO:0045670regulation of osteoclast differentiation0.0354718434540506
GO:0048706embryonic skeletal development0.0374431685213606
GO:0043233organelle lumen0.0377593851977914
GO:0031974membrane-enclosed lumen0.0377593851977914
GO:0002520immune system development0.0387961186000068
GO:0007212dopamine receptor signaling pathway0.0393181365829893
GO:0008277regulation of G-protein coupled receptor protein signaling pathway0.0393181365829893
GO:0002761regulation of myeloid leukocyte differentiation0.0393181365829893
GO:0017157regulation of exocytosis0.0393181365829893
GO:0017137Rab GTPase binding0.0411022280316904
GO:0017156calcium ion-dependent exocytosis0.0424588572380158
GO:0030316osteoclast differentiation0.0424588572380158
GO:0040018positive regulation of multicellular organism growth0.0462383828423891
GO:0043234protein complex0.0462383828423891
GO:0048705skeletal morphogenesis0.0462383828423891
GO:0035137hindlimb morphogenesis0.0462383828423891
GO:0001708cell fate specification0.0462383828423891
GO:0019319hexose biosynthetic process0.0462383828423891
GO:0046165alcohol biosynthetic process0.0493702570149621
GO:0046364monosaccharide biosynthetic process0.0493702570149621



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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