MCL coexpression mm9:282
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0015078 | hydrogen ion transmembrane transporter activity | 1.05733629719142e-22 |
GO:0015077 | monovalent inorganic cation transmembrane transporter activity | 1.05733629719142e-22 |
GO:0022890 | inorganic cation transmembrane transporter activity | 3.54830758606969e-21 |
GO:0005739 | mitochondrion | 9.86692785967779e-19 |
GO:0006091 | generation of precursor metabolites and energy | 2.4288803476115e-15 |
GO:0008324 | cation transmembrane transporter activity | 7.5024477992368e-15 |
GO:0015075 | ion transmembrane transporter activity | 1.87677659765519e-13 |
GO:0004129 | cytochrome-c oxidase activity | 1.87677659765519e-13 |
GO:0016676 | oxidoreductase activity, acting on heme group of donors, oxygen as acceptor | 1.87677659765519e-13 |
GO:0015002 | heme-copper terminal oxidase activity | 1.87677659765519e-13 |
GO:0016675 | oxidoreductase activity, acting on heme group of donors | 1.87677659765519e-13 |
GO:0022891 | substrate-specific transmembrane transporter activity | 8.03203548082412e-13 |
GO:0005743 | mitochondrial inner membrane | 1.79294810501441e-12 |
GO:0019866 | organelle inner membrane | 2.36125922112985e-12 |
GO:0031966 | mitochondrial membrane | 3.19913423151459e-12 |
GO:0022857 | transmembrane transporter activity | 3.45313822500132e-12 |
GO:0005740 | mitochondrial envelope | 5.69069868358036e-12 |
GO:0022892 | substrate-specific transporter activity | 9.04729830375329e-12 |
GO:0044429 | mitochondrial part | 2.24664088917973e-11 |
GO:0045259 | proton-transporting ATP synthase complex | 2.47998723586563e-11 |
GO:0044444 | cytoplasmic part | 4.04478104000245e-11 |
GO:0016491 | oxidoreductase activity | 4.14035824222607e-11 |
GO:0031975 | envelope | 8.25689641937836e-11 |
GO:0031967 | organelle envelope | 8.25689641937836e-11 |
GO:0005746 | mitochondrial respiratory chain | 2.26330566003301e-10 |
GO:0006754 | ATP biosynthetic process | 7.71766825778342e-10 |
GO:0006753 | nucleoside phosphate metabolic process | 7.71766825778342e-10 |
GO:0046933 | hydrogen ion transporting ATP synthase activity, rotational mechanism | 7.71766825778342e-10 |
GO:0006118 | electron transport | 8.05556299087337e-10 |
GO:0016469 | proton-transporting two-sector ATPase complex | 8.05556299087337e-10 |
GO:0046961 | hydrogen ion transporting ATPase activity, rotational mechanism | 8.05556299087337e-10 |
GO:0046034 | ATP metabolic process | 1.14142287713848e-09 |
GO:0031090 | organelle membrane | 1.14142287713848e-09 |
GO:0044455 | mitochondrial membrane part | 1.82288624436117e-09 |
GO:0009145 | purine nucleoside triphosphate biosynthetic process | 1.88343627958062e-09 |
GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 1.88343627958062e-09 |
GO:0009201 | ribonucleoside triphosphate biosynthetic process | 1.88343627958062e-09 |
GO:0019829 | cation-transporting ATPase activity | 2.29993136824492e-09 |
GO:0009142 | nucleoside triphosphate biosynthetic process | 2.50016271453906e-09 |
GO:0009205 | purine ribonucleoside triphosphate metabolic process | 2.71317565922131e-09 |
GO:0009199 | ribonucleoside triphosphate metabolic process | 2.93949786269354e-09 |
GO:0006119 | oxidative phosphorylation | 3.10572142613345e-09 |
GO:0009144 | purine nucleoside triphosphate metabolic process | 3.10572142613345e-09 |
GO:0015992 | proton transport | 3.70374928605004e-09 |
GO:0006752 | group transfer coenzyme metabolic process | 3.98878846161067e-09 |
GO:0009141 | nucleoside triphosphate metabolic process | 4.70792313813386e-09 |
GO:0009152 | purine ribonucleotide biosynthetic process | 5.04803559962466e-09 |
GO:0006818 | hydrogen transport | 5.40620743321387e-09 |
GO:0009260 | ribonucleotide biosynthetic process | 6.86453453459934e-09 |
GO:0009150 | purine ribonucleotide metabolic process | 8.60754032332113e-09 |
GO:0006164 | purine nucleotide biosynthetic process | 9.13697633655863e-09 |
GO:0009259 | ribonucleotide metabolic process | 1.30947163954274e-08 |
GO:0006163 | purine nucleotide metabolic process | 1.70623179333128e-08 |
GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | 2.65334621531328e-08 |
GO:0009108 | coenzyme biosynthetic process | 2.94886131388546e-08 |
GO:0015985 | energy coupled proton transport, down electrochemical gradient | 4.44895075053608e-08 |
GO:0015986 | ATP synthesis coupled proton transport | 4.44895075053608e-08 |
GO:0051188 | cofactor biosynthetic process | 5.8450139263461e-08 |
GO:0005737 | cytoplasm | 8.7239609072799e-08 |
GO:0043492 | ATPase activity, coupled to movement of substances | 1.38094086905866e-07 |
GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 1.38094086905866e-07 |
GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 1.41908810414275e-07 |
GO:0009165 | nucleotide biosynthetic process | 1.79897586450396e-07 |
GO:0015399 | primary active transmembrane transporter activity | 2.21809094621284e-07 |
GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | 2.21809094621284e-07 |
GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o) | 3.48517249543282e-07 |
GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain | 3.48517249543282e-07 |
GO:0006732 | coenzyme metabolic process | 6.26132608600419e-07 |
GO:0009117 | nucleotide metabolic process | 1.17448947152925e-06 |
GO:0051186 | cofactor metabolic process | 1.3606977549702e-06 |
GO:0043231 | intracellular membrane-bound organelle | 1.43698032170725e-06 |
GO:0043227 | membrane-bound organelle | 1.44178994678713e-06 |
GO:0055086 | nucleobase, nucleoside and nucleotide metabolic process | 1.56499460731309e-06 |
GO:0042623 | ATPase activity, coupled | 3.20782411227553e-06 |
GO:0045277 | respiratory chain complex IV | 5.12142662743087e-06 |
GO:0005751 | mitochondrial respiratory chain complex IV | 5.12142662743087e-06 |
GO:0016887 | ATPase activity | 6.38709978841597e-06 |
GO:0015672 | monovalent inorganic cation transport | 9.85818446189381e-06 |
GO:0009055 | electron carrier activity | 1.3099532405824e-05 |
GO:0022804 | active transmembrane transporter activity | 1.53804529191378e-05 |
GO:0043229 | intracellular organelle | 1.56591431738442e-05 |
GO:0043226 | organelle | 1.56802140393725e-05 |
GO:0050136 | NADH dehydrogenase (quinone) activity | 1.85878917188007e-05 |
GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 1.85878917188007e-05 |
GO:0003954 | NADH dehydrogenase activity | 1.85878917188007e-05 |
GO:0016655 | oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor | 2.22593648814792e-05 |
GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1) | 2.23327021135196e-05 |
GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain | 3.0893555504857e-05 |
GO:0016651 | oxidoreductase activity, acting on NADH or NADPH | 5.29021266596043e-05 |
GO:0017111 | nucleoside-triphosphatase activity | 7.30249867802728e-05 |
GO:0006812 | cation transport | 8.28326688719e-05 |
GO:0016462 | pyrophosphatase activity | 9.07913750686655e-05 |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 9.25249537390662e-05 |
GO:0016817 | hydrolase activity, acting on acid anhydrides | 9.25249537390662e-05 |
GO:0044446 | intracellular organelle part | 0.000118210290136629 |
GO:0044422 | organelle part | 0.000120296055700488 |
GO:0016020 | membrane | 0.000222191969850013 |
GO:0044424 | intracellular part | 0.000311841004108929 |
GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism | 0.000357569312107896 |
GO:0016310 | phosphorylation | 0.000419934088670099 |
GO:0043234 | protein complex | 0.000462971162058658 |
GO:0006811 | ion transport | 0.000509175039586427 |
GO:0005622 | intracellular | 0.000510439505774936 |
GO:0006793 | phosphorus metabolic process | 0.000868157074691329 |
GO:0006796 | phosphate metabolic process | 0.000868157074691329 |
GO:0044249 | cellular biosynthetic process | 0.00119791353739778 |
GO:0032991 | macromolecular complex | 0.00179250151765528 |
GO:0015662 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | 0.00206099288275178 |
GO:0004450 | isocitrate dehydrogenase (NADP+) activity | 0.00403514912425858 |
GO:0006097 | glyoxylate cycle | 0.00403514912425858 |
GO:0009058 | biosynthetic process | 0.00440211700390514 |
GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c | 0.00523506662048088 |
GO:0046487 | glyoxylate metabolic process | 0.00523506662048088 |
GO:0004448 | isocitrate dehydrogenase activity | 0.00906907335524909 |
GO:0016681 | oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor | 0.0138616711060358 |
GO:0008121 | ubiquinol-cytochrome-c reductase activity | 0.0138616711060358 |
GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors | 0.0138616711060358 |
GO:0006081 | aldehyde metabolic process | 0.0149871073464189 |
GO:0006810 | transport | 0.0175507520279265 |
GO:0042775 | organelle ATP synthesis coupled electron transport | 0.0183974721949875 |
GO:0044425 | membrane part | 0.0185690319330983 |
GO:0051234 | establishment of localization | 0.0194144269875745 |
GO:0042773 | ATP synthesis coupled electron transport | 0.0203241207026174 |
GO:0006099 | tricarboxylic acid cycle | 0.0283744543440641 |
GO:0046356 | acetyl-CoA catabolic process | 0.0293074506563158 |
GO:0009060 | aerobic respiration | 0.03022462737763 |
GO:0051179 | localization | 0.0326273468132348 |
GO:0009109 | coenzyme catabolic process | 0.0331418405798954 |
GO:0045333 | cellular respiration | 0.0340040252329686 |
GO:0051187 | cofactor catabolic process | 0.0359605109405213 |
GO:0006084 | acetyl-CoA metabolic process | 0.0378832626877978 |
GO:0016787 | hydrolase activity | 0.040075716893728 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
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