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MCL coexpression mm9:311

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:30549364..30549374,-p@chr11:30549364..30549374
-
Mm9::chr11:30549375..30549413,-p1@Acyp2
Mm9::chr11:30549417..30549445,-p2@Acyp2
Mm9::chr15:97938965..97939006,+p1@Pfkm
Mm9::chr17:24769553..24769577,-p1@Tsc2
Mm9::chr17:72131974..72132061,+p@chr17:72131974..72132061
+
Mm9::chr1:183950388..183950422,-p2@Enah
Mm9::chr2:71205594..71205618,-p1@Slc25a12
Mm9::chr4:115457601..115457657,+p1@Atpaf1
Mm9::chr4:122878659..122878674,+p3@Nt5c1a
Mm9::chr4:151235807..151235870,-p1@Camta1
Mm9::chr5:111239099..111239132,-p2@Ulk1
Mm9::chr5:35399499..35399544,+p1@Dok7
Mm9::chr5:74038959..74038993,-p1@Sgcb
Mm9::chr5:89363237..89363264,+p6@Slc4a4
Mm9::chr6:127059535..127059587,-p1@9630033F20Rik
Mm9::chr7:112730112..112730128,-p4@Apbb1
Mm9::chr7:96780993..96781002,+p12@Me3
Mm9::chr7:96781009..96781052,+p4@Me3
Mm9::chr8:107800283..107800326,+p2@Nol3
Mm9::chr8:107800338..107800382,+p1@Nol3
Mm9::chr8:13287814..13287856,-p1@Dcun1d2
Mm9::chr8:7002766..7002788,-p@chr8:7002766..7002788
-
Mm9::chr8:75095912..75095923,+p3@Tmem38a
Mm9::chr8:75095968..75096013,+p2@Tmem38a
Mm9::chr9:122714642..122714698,+p1@D9Ertd402e


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0032990cell part morphogenesis0.0191122493797354
GO:0048858cell projection morphogenesis0.0191122493797354
GO:0030030cell projection organization and biogenesis0.0191122493797354
GO:0045792negative regulation of cell size0.0191277037517963
GO:0043112receptor metabolic process0.021094805142216
GO:0016528sarcoplasm0.021094805142216
GO:0007409axonogenesis0.021094805142216
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.021094805142216
GO:0048667neuron morphogenesis during differentiation0.021094805142216
GO:0048812neurite morphogenesis0.021094805142216
GO:0000904cellular morphogenesis during differentiation0.021094805142216
GO:0001843neural tube closure0.021094805142216
GO:0031175neurite development0.021094805142216
GO:0014020primary neural tube formation0.021094805142216
GO:0032989cellular structure morphogenesis0.021094805142216
GO:0000902cell morphogenesis0.021094805142216
GO:0021933radial glia guided migration of granule cell0.021094805142216
GO:0050757thymidylate synthase biosynthetic process0.021094805142216
GO:0008510sodium:bicarbonate symporter activity0.021094805142216
GO:0050760negative regulation of thymidylate synthase biosynthetic process0.021094805142216
GO:0051386regulation of nerve growth factor receptor signaling pathway0.021094805142216
GO:0050758regulation of thymidylate synthase biosynthetic process0.021094805142216
GO:0014067negative regulation of phosphoinositide 3-kinase cascade0.021094805142216
GO:0048666neuron development0.0246203393221278
GO:0001841neural tube formation0.0246703249895695
GO:0001839neural plate morphogenesis0.0246703249895695
GO:0001840neural plate development0.0246703249895695
GO:0001838embryonic epithelial tube formation0.0246703249895695
GO:0016044membrane organization and biogenesis0.0246703249895695
GO:0021915neural tube development0.0262137604618714
GO:0021932hindbrain radial glia guided cell migration0.0262137604618714
GO:0043490malate-aspartate shuttle0.0262137604618714
GO:0048670regulation of collateral sprouting0.0262137604618714
GO:0043547positive regulation of GTPase activity0.0262137604618714
GO:0014066regulation of phosphoinositide 3-kinase cascade0.0262137604618714
GO:0003998acylphosphatase activity0.0262137604618714
GO:0048671negative regulation of collateral sprouting0.0262137604618714
GO:0007167enzyme linked receptor protein signaling pathway0.0274931504544667
GO:0016477cell migration0.0284840120622137
GO:0016331morphogenesis of embryonic epithelium0.0284840120622137
GO:0030182neuron differentiation0.0285935180172963
GO:0007411axon guidance0.0290837250523788
GO:0007399nervous system development0.0290837250523788
GO:0014065phosphoinositide 3-kinase cascade0.0290837250523788
GO:00059456-phosphofructokinase complex0.0290837250523788
GO:0048668collateral sprouting0.0290837250523788
GO:0035035histone acetyltransferase binding0.0290837250523788
GO:0045749negative regulation of S phase of mitotic cell cycle0.0290837250523788
GO:0004473malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity0.0290837250523788
GO:0021535cell migration in hindbrain0.0290837250523788
GO:0048699generation of neurons0.0307620993761674
GO:0048468cell development0.0307620993761674
GO:0006928cell motility0.0307620993761674
GO:0051674localization of cell0.0307620993761674
GO:0031623receptor internalization0.0307620993761674
GO:0004470malic enzyme activity0.0307620993761674
GO:0021684cerebellar granular layer formation0.0307620993761674
GO:0051898negative regulation of protein kinase B signaling cascade0.0307620993761674
GO:0021683cerebellar granular layer morphogenesis0.0307620993761674
GO:00038726-phosphofructokinase activity0.0307620993761674
GO:0015701bicarbonate transport0.0307620993761674
GO:0021681cerebellar granular layer development0.0307620993761674
GO:0021707cerebellar granule cell differentiation0.0307620993761674
GO:0006810transport0.031108361863902
GO:0022008neurogenesis0.0313862890906252
GO:0043062extracellular structure organization and biogenesis0.0313862890906252
GO:0051234establishment of localization0.0327214534708273
GO:0008361regulation of cell size0.0327214534708273
GO:0006108malate metabolic process0.0327214534708273
GO:0051896regulation of protein kinase B signaling cascade0.0327214534708273
GO:0046626regulation of insulin receptor signaling pathway0.0327214534708273
GO:0033261regulation of progression through S phase0.0327214534708273
GO:0045930negative regulation of progression through mitotic cell cycle0.0327214534708273
GO:0007090regulation of S phase of mitotic cell cycle0.0327214534708273
GO:0045786negative regulation of progression through cell cycle0.0372347761055763
GO:0016012sarcoglycan complex0.0372347761055763
GO:0048011nerve growth factor receptor signaling pathway0.0372347761055763
GO:0005522profilin binding0.0372347761055763
GO:0002009morphogenesis of an epithelium0.0399934514235954
GO:0051320S phase0.0408046698041314
GO:0001540beta-amyloid binding0.0408046698041314
GO:0000084S phase of mitotic cell cycle0.0408046698041314
GO:0016011dystroglycan complex0.0408046698041314
GO:0016615malate dehydrogenase activity0.0439637854989046
GO:0050821protein stabilization0.0439637854989046
GO:0050918positive chemotaxis0.0439637854989046
GO:00082535'-nucleotidase activity0.0439637854989046
GO:0005452inorganic anion exchanger activity0.0439637854989046
GO:0008252nucleotidase activity0.0467783819454978
GO:0008443phosphofructokinase activity0.0467783819454978
GO:0031647regulation of protein stability0.0467783819454978
GO:0043648dicarboxylic acid metabolic process0.0467783819454978
GO:0048009insulin-like growth factor receptor signaling pathway0.0467783819454978
GO:0007010cytoskeleton organization and biogenesis0.0473879024900326
GO:0035239tube morphogenesis0.0474167201603526
GO:0051179localization0.0474167201603526
GO:0015380anion exchanger activity0.0493011957011837
GO:0017124SH3 domain binding0.0493011957011837



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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