MCL coexpression mm9:2957

Phase1 CAGE Peaks

	Short description
Mm9::chr15:103070243..103070319,-	p1@Cbx5
Mm9::chr15:9070072..9070125,-	p1@Skp2
Mm9::chr15:9070130..9070144,-	p2@Skp2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008634	negative regulation of survival gene product activity	0.0201605171157068
GO:0010369	chromocenter	0.030237461888318
GO:0045884	regulation of survival gene product activity	0.0369518351360465
GO:0000776	kinetochore	0.0375317308171338
GO:0005720	nuclear heterochromatin	0.0375317308171338
GO:0000082	G1/S transition of mitotic cell cycle	0.0375317308171338
GO:0000790	nuclear chromatin	0.0375317308171338
GO:0000792	heterochromatin	0.0375317308171338
GO:0000151	ubiquitin ligase complex	0.0375317308171338
GO:0051325	interphase	0.0375317308171338
GO:0051329	interphase of mitotic cell cycle	0.0375317308171338
GO:0000775	chromosome, pericentric region	0.0481553353915747
GO:0043234	protein complex	0.0481553353915747
GO:0044454	nuclear chromosome part	0.0481553353915747
GO:0006916	anti-apoptosis	0.0490389473501839
GO:0000228	nuclear chromosome	0.0490389473501839

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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