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MCL coexpression mm9:218

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:4847994..4848012,-p1@Nefh
Mm9::chr11:55421321..55421324,-p14@Glra1
Mm9::chr11:55421419..55421506,-p1@Glra1
Mm9::chr11:55421691..55421706,-p6@Glra1
Mm9::chr11:55421712..55421719,-p10@Glra1
Mm9::chr11:55421783..55421797,-p7@Glra1
Mm9::chr11:55422049..55422061,-p4@Glra1
Mm9::chr11:55422065..55422098,-p3@Glra1
Mm9::chr11:55422099..55422115,-p5@Glra1
Mm9::chr11:55422124..55422129,-p9@Glra1
Mm9::chr11:55422131..55422165,-p2@Glra1
Mm9::chr11:55886412..55886420,+p@chr11:55886412..55886420
+
Mm9::chr12:114040857..114040876,-p1@Ahnak2
Mm9::chr13:100286621..100286632,-p3@Mtap1b
Mm9::chr14:121739423..121739435,-p@chr14:121739423..121739435
-
Mm9::chr14:34183323..34183333,-p1@ENSMUST00000137359
Mm9::chr14:48339462..48339479,+p@chr14:48339462..48339479
+
Mm9::chr16:58677946..58677957,+p@chr16:58677946..58677957
+
Mm9::chr17:26341262..26341275,+p@chr17:26341262..26341275
+
Mm9::chr17:43786636..43786644,-p10@Slc25a27
Mm9::chr17:54436510..54436520,-p@chr17:54436510..54436520
-
Mm9::chr17:69476739..69476749,+p@chr17:69476739..69476749
+
Mm9::chr17:69476754..69476785,+p@chr17:69476754..69476785
+
Mm9::chr19:17030450..17030470,+p4@Prune2
Mm9::chr2:101660614..101660617,-p@chr2:101660614..101660617
-
Mm9::chr2:112411598..112411619,+p@chr2:112411598..112411619
+
Mm9::chr2:31133553..31133564,+p@chr2:31133553..31133564
+
Mm9::chr3:94203194..94203255,+p2@Lingo4
Mm9::chr4:137176954..137176965,+p8@LOC674195
p8@Usp48
Mm9::chr5:118399577..118399601,+p@chr5:118399577..118399601
+
Mm9::chr5:5694559..5694581,-p5@Steap2
Mm9::chr6:126668903..126668952,+p@chr6:126668903..126668952
+
Mm9::chr6:20963159..20963195,-p1@ENSMUST00000157206
Mm9::chr7:51079819..51079830,+p4@Klk6
Mm9::chr7:51079863..51079887,+p3@Klk6
Mm9::chr7:51079889..51079927,+p1@Klk6
Mm9::chr7:51848386..51848395,+p@chr7:51848386..51848395
+
Mm9::chr7:57165677..57165684,+p10@Slc6a5
Mm9::chr7:57165685..57165707,+p1@Slc6a5
Mm9::chr7:57165722..57165728,+p9@Slc6a5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005275amine transmembrane transporter activity0.0225085773427904
GO:0015370solute:sodium symporter activity0.0225085773427904
GO:0015294solute:cation symporter activity0.0225085773427904
GO:0015075ion transmembrane transporter activity0.0225085773427904
GO:0015837amine transport0.0225085773427904
GO:0008292acetylcholine biosynthetic process0.0225085773427904
GO:0042737drug catabolic process0.0225085773427904
GO:0005307choline:sodium symporter activity0.0225085773427904
GO:0042738exogenous drug catabolic process0.0225085773427904
GO:0050660FAD binding0.0225085773427904
GO:0000226microtubule cytoskeleton organization and biogenesis0.0225085773427904
GO:0006811ion transport0.0225085773427904
GO:0022891substrate-specific transmembrane transporter activity0.0225085773427904
GO:0044271nitrogen compound biosynthetic process0.0225085773427904
GO:0051926negative regulation of calcium ion transport0.0225085773427904
GO:0015871choline transport0.0225085773427904
GO:0043576regulation of respiratory gaseous exchange0.0225085773427904
GO:0060012synaptic transmission, glycinergic0.0225085773427904
GO:0008291acetylcholine metabolic process0.0225085773427904
GO:0015220choline transmembrane transporter activity0.0225085773427904
GO:0022857transmembrane transporter activity0.0225085773427904
GO:0006810transport0.0225085773427904
GO:0030001metal ion transport0.0225085773427904
GO:0051234establishment of localization0.0225085773427904
GO:0002087neurological control of breathing0.0225085773427904
GO:0004517nitric-oxide synthase activity0.0225085773427904
GO:0043267negative regulation of potassium ion transport0.0225085773427904
GO:0060081membrane hyperpolarization0.0225085773427904
GO:0045110intermediate filament bundle assembly0.0225085773427904
GO:0060080regulation of inhibitory postsynaptic membrane potential0.0225085773427904
GO:0015844monoamine transport0.0225085773427904
GO:0022892substrate-specific transporter activity0.0225707551282698
GO:0006814sodium ion transport0.0225707551282698
GO:0050662coenzyme binding0.0225707551282698
GO:0002028regulation of sodium ion transport0.0225707551282698
GO:0016594glycine binding0.0225707551282698
GO:0016934extracellular-glycine-gated chloride channel activity0.0225707551282698
GO:0043271negative regulation of ion transport0.0225707551282698
GO:0016933extracellular-glycine-gated ion channel activity0.0225707551282698
GO:0008504monoamine transmembrane transporter activity0.0225707551282698
GO:0042439ethanolamine and derivative metabolic process0.0225707551282698
GO:0005624membrane fraction0.0225707551282698
GO:0008324cation transmembrane transporter activity0.0225707551282698
GO:0006812cation transport0.0225707551282698
GO:0043266regulation of potassium ion transport0.0225707551282698
GO:0051346negative regulation of hydrolase activity0.0225707551282698
GO:0003016respiratory system process0.0225707551282698
GO:0060013righting reflex0.0225707551282698
GO:0006893Golgi to plasma membrane transport0.0225707551282698
GO:0017144drug metabolic process0.0225707551282698
GO:0015293symporter activity0.0225707551282698
GO:0015674di-, tri-valent inorganic cation transport0.0225707551282698
GO:0000267cell fraction0.0241222418234328
GO:0051179localization0.0241222418234328
GO:0050884neuromuscular process controlling posture0.0248976936058924
GO:0005883neurofilament0.0248976936058924
GO:0005519cytoskeletal regulatory protein binding0.0280372293627797
GO:0051924regulation of calcium ion transport0.0280372293627797
GO:0005886plasma membrane0.0299662575020012
GO:0048037cofactor binding0.0299662575020012
GO:0060004reflex0.0299662575020012
GO:0016597amino acid binding0.0299662575020012
GO:0045045secretory pathway0.0302828536927784
GO:0007017microtubule-based process0.0302828536927784
GO:0015291secondary active transmembrane transporter activity0.0302828536927784
GO:0001578microtubule bundle formation0.0302828536927784
GO:0060053neurofilament cytoskeleton0.0302828536927784
GO:0060052neurofilament cytoskeleton organization and biogenesis0.0302828536927784
GO:0045109intermediate filament organization0.0302828536927784
GO:0006892post-Golgi vesicle-mediated transport0.0322092060227591
GO:0007340acrosome reaction0.0322092060227591
GO:0010181FMN binding0.0322092060227591
GO:0007268synaptic transmission0.0322092060227591
GO:0050661NADP binding0.0344907557195294
GO:0032940secretion by cell0.03523425512745
GO:0048265response to pain0.03523425512745
GO:0043269regulation of ion transport0.03523425512745
GO:0001964startle response0.03523425512745
GO:0060078regulation of postsynaptic membrane potential0.03523425512745
GO:0007274neuromuscular synaptic transmission0.036319963501225
GO:0007271synaptic transmission, cholinergic0.036319963501225
GO:0004293tissue kallikrein activity0.036319963501225
GO:0042136neurotransmitter biosynthetic process0.036319963501225
GO:0019226transmission of nerve impulse0.0387874874124148
GO:0043176amine binding0.0408969489234937
GO:0045104intermediate filament cytoskeleton organization and biogenesis0.0447428136131082
GO:0006809nitric oxide biosynthetic process0.0447428136131082
GO:0046209nitric oxide metabolic process0.0447428136131082
GO:0051051negative regulation of transport0.0463080275310763
GO:0005328neurotransmitter:sodium symporter activity0.0463080275310763
GO:0046903secretion0.0468846965000058
GO:0007585respiratory gaseous exchange0.0478036782542486
GO:0017156calcium ion-dependent exocytosis0.0487159519888813
GO:0005326neurotransmitter transporter activity0.0487159519888813
GO:0045103intermediate filament-based process0.0487159519888813



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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