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MCL coexpression mm9:301

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:77647847..77647900,-p1@Pwp2
Mm9::chr11:6167721..6167758,-p1@Ddx56
Mm9::chr11:64792527..64792612,+p1@Elac2
Mm9::chr11:72254843..72254888,+p1@Mybbp1a
Mm9::chr13:107737184..107737244,+p1@Dimt1
Mm9::chr13:3610310..3610364,-p1@BC016423
Mm9::chr13:54691408..54691450,-p1@Nop16
Mm9::chr17:24844562..24844606,-p1@Tbl3
Mm9::chr17:32173344..32173398,+p1@Rrp1b
Mm9::chr17:47748160..47748193,-p1@Bysl
Mm9::chr19:41970650..41970697,-p1@Rrp12
Mm9::chr19:46131044..46131076,+p1@Pprc1
Mm9::chr1:164478615..164478676,-p1@Mettl13
Mm9::chr1:9535478..9535560,+p1@Rrs1
Mm9::chr3:105762371..105762459,+p1@Wdr77
Mm9::chr3:129534207..129534259,-p2@Gar1
Mm9::chr4:120242857..120242904,-p1@Ctps
Mm9::chr4:151413424..151413465,+p1@Nol9
Mm9::chr4:155610108..155610159,+p@chr4:155610108..155610159
+
Mm9::chr4:45031491..45031547,+p1@Polr1e
Mm9::chr5:111082463..111082501,+p1@Ddx51
Mm9::chr5:120566489..120566534,+p1@Rbm19
Mm9::chr5:74489137..74489154,+p1@2700023E23Rik
Mm9::chr6:125081887..125081971,+p1@Nop2
Mm9::chr7:5013785..5013843,+p1@U2af2
Mm9::chr7:53086146..53086186,-p1@Grwd1
Mm9::chr8:90661743..90661801,+p1@Heatr3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042254ribosome biogenesis and assembly5.11680186249144e-07
GO:0022613ribonucleoprotein complex biogenesis and assembly3.20675718272105e-06
GO:0005730nucleolus4.9783549932582e-06
GO:0016072rRNA metabolic process9.72423441477556e-06
GO:0006364rRNA processing9.72423441477556e-06
GO:0005634nucleus1.35386557805915e-05
GO:0003723RNA binding2.30020001477502e-05
GO:0006396RNA processing2.86814449429933e-05
GO:0016070RNA metabolic process0.00418132620189929
GO:0043231intracellular membrane-bound organelle0.00418132620189929
GO:0043227membrane-bound organelle0.00418132620189929
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0057915285466571
GO:0044428nuclear part0.0057915285466571
GO:0031981nuclear lumen0.00651548456133426
GO:0006996organelle organization and biogenesis0.00855697563088129
GO:0031974membrane-enclosed lumen0.00855697563088129
GO:0043233organelle lumen0.00855697563088129
GO:0010467gene expression0.00855697563088129
GO:0031074nucleocytoplasmic shuttling complex0.00855697563088129
GO:0042564NLS-dependent protein nuclear import complex0.00855697563088129
GO:0001651dense fibrillar component0.00855697563088129
GO:0003676nucleic acid binding0.00929918789864357
GO:0043229intracellular organelle0.0121978450728034
GO:0043226organelle0.0121978450728034
GO:0003883CTP synthase activity0.0138156121431303
GO:0030515snoRNA binding0.0138156121431303
GO:0000179rRNA (adenine-N6,N6-)-dimethyltransferase activity0.0179509488968946
GO:0016433rRNA (adenine) methyltransferase activity0.0179509488968946
GO:0008649rRNA methyltransferase activity0.0179509488968946
GO:0008026ATP-dependent helicase activity0.0181160658139124
GO:0000154rRNA modification0.0224270101912869
GO:0009303rRNA transcription0.0271701114396692
GO:0016779nucleotidyltransferase activity0.0285973935560174
GO:0004386helicase activity0.0388005106397328
GO:0016043cellular component organization and biogenesis0.0408817001251616



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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