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Coexpression cluster:C271

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Full id: C271_pineal_spinal_locus_globus_medulla_thalamus_cerebellum



Phase1 CAGE Peaks

Hg19::chr10:103599591..103599635,-p3@KCNIP2
Hg19::chr10:64133934..64133954,+p6@ZNF365
Hg19::chr10:94000157..94000191,-p6@CPEB3
Hg19::chr11:131240498..131240532,+p1@NTM
Hg19::chr11:131240536..131240547,+p4@NTM
Hg19::chr11:131240548..131240559,+p10@NTM
Hg19::chr11:131240565..131240572,+p13@NTM
Hg19::chr12:131201033..131201041,-p3@RIMBP2
Hg19::chr12:22487588..22487616,-p3@ST8SIA1
Hg19::chr12:22487618..22487648,-p1@ST8SIA1
Hg19::chr12:26274116..26274141,-p2@AK094422
Hg19::chr12:71314617..71314622,-p16@PTPRR
Hg19::chr14:32547434..32547446,+p11@ARHGAP5
Hg19::chr15:79575073..79575138,+p1@ANKRD34C
Hg19::chr17:55757077..55757089,+p@chr17:55757077..55757089
+
Hg19::chr17:7554234..7554251,+p1@ATP1B2
Hg19::chr17:7556683..7556703,+p@chr17:7556683..7556703
+
Hg19::chr17:7556754..7556788,+p@chr17:7556754..7556788
+
Hg19::chr17:7557938..7557979,+p@chr17:7557938..7557979
+
Hg19::chr17:7559125..7559140,+p@chr17:7559125..7559140
+
Hg19::chr17:7559212..7559223,+p@chr17:7559212..7559223
+
Hg19::chr17:7559305..7559325,+p@chr17:7559305..7559325
+
Hg19::chr17:7559346..7559354,+p@chr17:7559346..7559354
+
Hg19::chr17:7559648..7559652,+p16@ATP1B2
Hg19::chr17:7560487..7560497,+p11@ATP1B2
Hg19::chr17:7560507..7560534,+p2@ATP1B2
Hg19::chr17:7560542..7560578,+p4@ATP1B2
Hg19::chr17:7560589..7560611,+p8@ATP1B2
Hg19::chr17:7560617..7560658,+p5@ATP1B2
Hg19::chr17:7560779..7560820,+p3@ATP1B2
Hg19::chr19:30715705..30715726,+p@chr19:30715705..30715726
+
Hg19::chr19:52452374..52452419,+p1@ENST00000500242
p1@uc002pyb.2
p1@uc002pyc.2
Hg19::chr1:10436637..10436646,+p@chr1:10436637..10436646
+
Hg19::chr1:197237352..197237414,+p2@CRB1
Hg19::chr1:216680100..216680145,-p@chr1:216680100..216680145
-
Hg19::chr2:220154660..220154662,-p@chr2:220154660..220154662
-
Hg19::chr4:170581337..170581344,+p10@CLCN3
Hg19::chr4:187112411..187112444,+p7@CYP4V2
Hg19::chr6:87646995..87647024,+p2@HTR1E
Hg19::chr7:128864848..128864913,+p1@AHCYL2
Hg19::chr7:130152491..130152507,+p@chr7:130152491..130152507
+
Hg19::chr9:35829208..35829308,+p1@TMEM8B
Hg19::chr9:99449322..99449347,+p1@ENST00000423924
Hg19::chrX:144899314..144899392,+p1@SLITRK2
Hg19::chrX:144899416..144899486,+p3@SLITRK2
Hg19::chrX:144899488..144899501,+p4@SLITRK2
Hg19::chrX:144903040..144903070,+p2@SLITRK2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0044425membrane part0.0157114682679854
GO:0016020membrane0.0157114682679854
GO:0016021integral to membrane0.0157114682679854
GO:0016324apical plasma membrane0.0157114682679854
GO:0031224intrinsic to membrane0.0157114682679854
GO:0032501multicellular organismal process0.0157114682679854
GO:0048388endosomal lumen acidification0.0157114682679854
GO:0045163clustering of voltage-gated potassium channels0.0157114682679854
GO:0045177apical part of cell0.0191512452993784
GO:0009653anatomical structure morphogenesis0.01982022288438
GO:0005250A-type (transient outward) potassium channel activity0.01982022288438
GO:0032989cellular structure morphogenesis0.01982022288438
GO:0000902cell morphogenesis0.01982022288438
GO:0048856anatomical structure development0.01982022288438
GO:0019904protein domain specific binding0.0229795800062908
GO:0032502developmental process0.0229795800062908
GO:0050877neurological system process0.0229795800062908
GO:0030955potassium ion binding0.0229795800062908
GO:0044459plasma membrane part0.0229795800062908
GO:0015271outward rectifier potassium channel activity0.0229795800062908
GO:0003828alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity0.0229795800062908
GO:0009986cell surface0.0229795800062908
GO:0048666neuron development0.0237715222228541
GO:0045161neuronal ion channel clustering0.0253099614812186
GO:0007267cell-cell signaling0.0253099614812186
GO:0045851pH reduction0.0296281311295286
GO:0051453regulation of cellular pH0.0296281311295286
GO:0051452cellular pH reduction0.0296281311295286
GO:0046923ER retention sequence binding0.0296281311295286
GO:0003008system process0.0296281311295286
GO:0007032endosome organization and biogenesis0.0304581850844502
GO:0005513detection of calcium ion0.0304581850844502
GO:0030182neuron differentiation0.0304581850844502
GO:0031420alkali metal ion binding0.0313964221689795
GO:0007601visual perception0.0313964221689795
GO:0050953sensory perception of light stimulus0.0313964221689795
GO:0006688glycosphingolipid biosynthetic process0.0330198688334164
GO:0042551neuron maturation0.0330198688334164
GO:0048699generation of neurons0.0339901125499411
GO:0006813potassium ion transport0.0367104905655899
GO:0030641cellular hydrogen ion homeostasis0.0367104905655899
GO:0022008neurogenesis0.0368328655832253
GO:0004993serotonin receptor activity0.0379126926495747
GO:0030004cellular monovalent inorganic cation homeostasis0.0400758765880435
GO:0009247glycolipid biosynthetic process0.0400758765880435
GO:0055067monovalent inorganic cation homeostasis0.0400758765880435
GO:0007268synaptic transmission0.0400758765880435
GO:0031901early endosome membrane0.0409695555806811
GO:0005391sodium:potassium-exchanging ATPase activity0.0409695555806811
GO:0042169SH2 domain binding0.0409695555806811
GO:0009593detection of chemical stimulus0.0409695555806811
GO:0022832voltage-gated channel activity0.0409695555806811
GO:0005244voltage-gated ion channel activity0.0409695555806811
GO:0019198transmembrane receptor protein phosphatase activity0.0409695555806811
GO:0005001transmembrane receptor protein tyrosine phosphatase activity0.0409695555806811
GO:0006687glycosphingolipid metabolic process0.0409695555806811
GO:0012505endomembrane system0.0409695555806811
GO:0016043cellular component organization and biogenesis0.0409695555806811
GO:0019226transmission of nerve impulse0.0409695555806811
GO:0030165PDZ domain binding0.041745255595325
GO:0005048signal sequence binding0.0424104566331044
GO:0030148sphingolipid biosynthetic process0.0424104566331044
GO:0000139Golgi membrane0.0465679210758911
GO:0005100Rho GTPase activator activity0.046927511566585



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

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