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Coexpression cluster:C626

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Full id: C626_penis_skeletal_tongue_diaphragm_salivary_throat_Adipocyte



Phase1 CAGE Peaks

Hg19::chr12:53068552..53068579,-p@chr12:53068552..53068579
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Hg19::chr12:53068835..53068874,-p@chr12:53068835..53068874
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Hg19::chr12:53068889..53068898,-p@chr12:53068889..53068898
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Hg19::chr12:53068923..53068932,-p@chr12:53068923..53068932
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Hg19::chr17:10401094..10401106,-p@chr17:10401094..10401106
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Hg19::chr17:38974394..38974440,-p@chr17:38974394..38974440
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Hg19::chr17:4448859..4448864,-p@chr17:4448859..4448864
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Hg19::chr20:33451391..33451397,-p6@GGT7
Hg19::chr2:178753478..178753487,-p10@PDE11A
Hg19::chr2:179433518..179433530,-p@chr2:179433518..179433530
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Hg19::chr2:179595422..179595432,-p@chr2:179595422..179595432
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Hg19::chr2:179640441..179640449,-p107@TTN
Hg19::chr3:155838361..155838382,+p10@KCNAB1
Hg19::chrX:135292261..135292285,+p@chrX:135292261..135292285
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0051393alpha-actinin binding0.0168507433336938
GO:0042805actinin binding0.0168507433336938
GO:00475553',5'-cyclic-GMP phosphodiesterase activity0.0168507433336938
GO:0030239myofibril assembly0.0168507433336938
GO:0055001muscle cell development0.0168507433336938
GO:0055002striated muscle cell development0.0168507433336938
GO:0017022myosin binding0.0168507433336938
GO:0048628myoblast maturation0.0180193423251079
GO:0048627myoblast development0.0180193423251079
GO:0030018Z disc0.0204093141395362
GO:0051146striated muscle cell differentiation0.0204093141395362
GO:0031674I band0.0204093141395362
GO:0015459potassium channel regulator activity0.0204093141395362
GO:0031032actomyosin structure organization and biogenesis0.0221081374747377
GO:0045445myoblast differentiation0.025174788347535
GO:0000794condensed nuclear chromosome0.025174788347535
GO:0016247channel regulator activity0.025174788347535
GO:0006941striated muscle contraction0.025174788347535
GO:0048741skeletal muscle fiber development0.025174788347535
GO:0008307structural constituent of muscle0.025174788347535
GO:0048747muscle fiber development0.025174788347535
GO:0046777protein amino acid autophosphorylation0.025174788347535
GO:0048469cell maturation0.025174788347535
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.025174788347535
GO:0042692muscle cell differentiation0.025174788347535
GO:0016540protein autoprocessing0.025174788347535
GO:0004112cyclic-nucleotide phosphodiesterase activity0.025174788347535
GO:0030017sarcomere0.025174788347535
GO:0000793condensed chromosome0.025174788347535
GO:0030016myofibril0.025174788347535
GO:0021700developmental maturation0.025174788347535
GO:0044449contractile fiber part0.0276034512261386
GO:0043292contractile fiber0.0285480848324906
GO:0007519skeletal muscle development0.0290047049993703
GO:0014706striated muscle development0.036984395187087
GO:0016485protein processing0.0393456394331647
GO:0000228nuclear chromosome0.0393456394331647
GO:0005737cytoplasm0.0469339209353349



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fat cell3.67e-1015
Uber Anatomy
Ontology termp-valuen
adult organism7.01e-21115
organism subdivision1.21e-07365
surface structure7.15e-0795


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.