MCL coexpression mm9:201
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005739 | mitochondrion | 1.65811560632517e-24 |
GO:0044444 | cytoplasmic part | 2.17946459373208e-15 |
GO:0006631 | fatty acid metabolic process | 3.82667074135426e-12 |
GO:0032787 | monocarboxylic acid metabolic process | 5.12862614991152e-11 |
GO:0005737 | cytoplasm | 1.964865736978e-10 |
GO:0044255 | cellular lipid metabolic process | 3.34493415359138e-10 |
GO:0006629 | lipid metabolic process | 1.28791363384986e-09 |
GO:0044429 | mitochondrial part | 1.28791363384986e-09 |
GO:0016491 | oxidoreductase activity | 1.29731816147466e-09 |
GO:0043231 | intracellular membrane-bound organelle | 2.05668062419536e-09 |
GO:0043227 | membrane-bound organelle | 2.05668062419536e-09 |
GO:0050660 | FAD binding | 1.07635838369545e-08 |
GO:0019752 | carboxylic acid metabolic process | 2.21887555043635e-08 |
GO:0006082 | organic acid metabolic process | 2.21887555043635e-08 |
GO:0031966 | mitochondrial membrane | 6.95686117003045e-08 |
GO:0017133 | mitochondrial electron transfer flavoprotein complex | 6.95686117003045e-08 |
GO:0045251 | electron transfer flavoprotein complex | 6.95686117003045e-08 |
GO:0043229 | intracellular organelle | 8.31833272040718e-08 |
GO:0043226 | organelle | 8.31833272040718e-08 |
GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | 9.42708710462091e-08 |
GO:0005740 | mitochondrial envelope | 9.98768518676619e-08 |
GO:0006091 | generation of precursor metabolites and energy | 1.30954445229854e-07 |
GO:0003995 | acyl-CoA dehydrogenase activity | 1.31583543614201e-07 |
GO:0006118 | electron transport | 3.00563266219292e-07 |
GO:0050662 | coenzyme binding | 3.19863354718234e-07 |
GO:0005743 | mitochondrial inner membrane | 6.94884590039665e-07 |
GO:0019866 | organelle inner membrane | 8.41320618852152e-07 |
GO:0031090 | organelle membrane | 8.41320618852152e-07 |
GO:0031975 | envelope | 9.4794313635429e-07 |
GO:0031967 | organelle envelope | 9.4794313635429e-07 |
GO:0048037 | cofactor binding | 2.34431853847999e-06 |
GO:0016408 | C-acyltransferase activity | 6.04619670303629e-06 |
GO:0044424 | intracellular part | 9.81965099562373e-06 |
GO:0016649 | oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor | 2.23136533387483e-05 |
GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity | 2.23136533387483e-05 |
GO:0005622 | intracellular | 2.23136533387483e-05 |
GO:0019395 | fatty acid oxidation | 3.57827918294243e-05 |
GO:0003988 | acetyl-CoA C-acyltransferase activity | 6.3051334652743e-05 |
GO:0004300 | enoyl-CoA hydratase activity | 0.000119679395567415 |
GO:0003985 | acetyl-CoA C-acetyltransferase activity | 0.000119679395567415 |
GO:0016453 | C-acetyltransferase activity | 0.000194408750444265 |
GO:0009055 | electron carrier activity | 0.000473241497485848 |
GO:0005759 | mitochondrial matrix | 0.000596910453837229 |
GO:0031980 | mitochondrial lumen | 0.000596910453837229 |
GO:0006635 | fatty acid beta-oxidation | 0.00137074076337276 |
GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | 0.00323241232455029 |
GO:0044446 | intracellular organelle part | 0.00323241232455029 |
GO:0044422 | organelle part | 0.00326303287681961 |
GO:0004466 | long-chain-acyl-CoA dehydrogenase activity | 0.00930571099858341 |
GO:0004001 | adenosine kinase activity | 0.00930571099858341 |
GO:0009054 | electron acceptor activity | 0.00930571099858341 |
GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex | 0.00930571099858341 |
GO:0016508 | long-chain-enoyl-CoA hydratase activity | 0.00930571099858341 |
GO:0004085 | butyryl-CoA dehydrogenase activity | 0.00930571099858341 |
GO:0048244 | phytanoyl-CoA dioxygenase activity | 0.00930571099858341 |
GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity | 0.00930571099858341 |
GO:0044238 | primary metabolic process | 0.0134292477774332 |
GO:0008415 | acyltransferase activity | 0.0134292477774332 |
GO:0019867 | outer membrane | 0.0134292477774332 |
GO:0016747 | transferase activity, transferring groups other than amino-acyl groups | 0.0134921306993982 |
GO:0016836 | hydro-lyase activity | 0.0146278648282746 |
GO:0016746 | transferase activity, transferring acyl groups | 0.0146278648282746 |
GO:0017076 | purine nucleotide binding | 0.0152679599825912 |
GO:0004776 | succinate-CoA ligase (GDP-forming) activity | 0.0155438834799722 |
GO:0001561 | fatty acid alpha-oxidation | 0.0155438834799722 |
GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity | 0.0155438834799722 |
GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity | 0.0155438834799722 |
GO:0016407 | acetyltransferase activity | 0.0170747080902416 |
GO:0030554 | adenyl nucleotide binding | 0.0170747080902416 |
GO:0044464 | cell part | 0.0170747080902416 |
GO:0005623 | cell | 0.0170747080902416 |
GO:0016835 | carbon-oxygen lyase activity | 0.0179611104752788 |
GO:0001574 | ganglioside biosynthetic process | 0.0202722378490755 |
GO:0043174 | nucleoside salvage | 0.0202722378490755 |
GO:0004774 | succinate-CoA ligase activity | 0.0202722378490755 |
GO:0006166 | purine ribonucleoside salvage | 0.0202722378490755 |
GO:0043101 | purine salvage | 0.0202722378490755 |
GO:0046467 | membrane lipid biosynthetic process | 0.0244534639900949 |
GO:0000166 | nucleotide binding | 0.02536204098249 |
GO:0046128 | purine ribonucleoside metabolic process | 0.02536204098249 |
GO:0009437 | carnitine metabolic process | 0.02536204098249 |
GO:0043094 | metabolic compound salvage | 0.02536204098249 |
GO:0005498 | sterol carrier activity | 0.030560194247214 |
GO:0042278 | purine nucleoside metabolic process | 0.030560194247214 |
GO:0006688 | glycosphingolipid biosynthetic process | 0.030560194247214 |
GO:0044237 | cellular metabolic process | 0.0319559371146957 |
GO:0042579 | microbody | 0.0319559371146957 |
GO:0005777 | peroxisome | 0.0319559371146957 |
GO:0006309 | DNA fragmentation during apoptosis | 0.0399021080604241 |
GO:0016405 | CoA-ligase activity | 0.0399021080604241 |
GO:0009119 | ribonucleoside metabolic process | 0.0399021080604241 |
GO:0009409 | response to cold | 0.0436488458499015 |
GO:0001573 | ganglioside metabolic process | 0.0436488458499015 |
GO:0009247 | glycolipid biosynthetic process | 0.0436488458499015 |
GO:0006921 | cell structure disassembly during apoptosis | 0.0436488458499015 |
GO:0042594 | response to starvation | 0.0480556462130121 |
GO:0030262 | apoptotic nuclear changes | 0.0480556462130121 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
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