MCL coexpression mm9:244

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127934445..127934460,-	p@chr10:127934445..127934460 -
Mm9::chr11:11736215..11736234,-	p6@Ddc
Mm9::chr11:66891795..66891809,+	p1@Myh3
Mm9::chr11:67090670..67090685,+	p3@Myh8
Mm9::chr11:78860985..78860998,-	p@chr11:78860985..78860998 -
Mm9::chr11:85553408..85553419,+	p@chr11:85553408..85553419 +
Mm9::chr11:85553433..85553449,+	p@chr11:85553433..85553449 +
Mm9::chr11:85553450..85553467,+	p@chr11:85553450..85553467 +
Mm9::chr14:61748215..61748225,+	p@chr14:61748215..61748225 +
Mm9::chr16:87553762..87553775,+	p3@ORF63
Mm9::chr17:57144287..57144315,-	p@chr17:57144287..57144315 -
Mm9::chr18:14490364..14490376,+	p@chr18:14490364..14490376 +
Mm9::chr18:9282716..9282737,-	p1@Gjd4
Mm9::chr1:195024087..195024100,-	p4@Traf3ip3
Mm9::chr1:20659960..20659965,+	p@chr1:20659960..20659965 +
Mm9::chr1:89087199..89087215,+	p1@Chrnd
Mm9::chr2:26927636..26927690,-	p1@Tmem8c
Mm9::chr2:26927695..26927706,-	p3@Tmem8c
Mm9::chr2:26927723..26927736,-	p2@Tmem8c
Mm9::chr2:32231819..32231835,+	p@chr2:32231819..32231835 +
Mm9::chr4:57509423..57509468,-	p@chr4:57509423..57509468 -
Mm9::chr7:149850690..149850736,-	p@chr7:149850690..149850736 -
Mm9::chr7:149851034..149851062,+	p1@ENSMUST00000124393
Mm9::chr7:149851708..149851725,+	p@chr7:149851708..149851725 +
Mm9::chr7:52895254..52895267,+	p3@Mamstr
Mm9::chr7:56627564..56627586,+	p@chr7:56627564..56627586 +
Mm9::chr7:56627587..56627609,+	p@chr7:56627587..56627609 +
Mm9::chr7:56627610..56627621,+	p@chr7:56627610..56627621 +
Mm9::chr7:97763588..97763602,+	p@chr7:97763588..97763602 +
Mm9::chr8:15060314..15060346,+	p4@Myom2
Mm9::chrX:109058005..109058019,+	p@chrX:109058005..109058019 +
Mm9::chrX:22843877..22843932,-	p4@Klhl13
Mm9::chrX:46817103..46817150,+	p3@Arhgap36
Mm9::chrX:47132360..47132371,-	p@chrX:47132360..47132371 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0032982	myosin filament	9.76695101994067e-07
GO:0005863	striated muscle thick filament	9.76695101994067e-07
GO:0005859	muscle myosin complex	9.76695101994067e-07
GO:0016460	myosin II complex	1.12649264147249e-06
GO:0006941	striated muscle contraction	5.86459433916485e-06
GO:0016459	myosin complex	3.89099431944124e-05
GO:0030017	sarcomere	5.20620022734386e-05
GO:0044449	contractile fiber part	5.2126216070485e-05
GO:0030016	myofibril	5.81250692676225e-05
GO:0043292	contractile fiber	5.81250692676225e-05
GO:0003012	muscle system process	6.07654751973719e-05
GO:0006936	muscle contraction	6.07654751973719e-05
GO:0015629	actin cytoskeleton	0.000671897870755431
GO:0043234	protein complex	0.00211056088786752
GO:0004058	aromatic-L-amino-acid decarboxylase activity	0.00426596541207838
GO:0032991	macromolecular complex	0.00552955323598374
GO:0044430	cytoskeletal part	0.00993483187520388
GO:0042166	acetylcholine binding	0.0248561824957541
GO:0008307	structural constituent of muscle	0.0269067972055477
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	0.0304186392640424
GO:0042423	catecholamine biosynthetic process	0.0304186392640424
GO:0003779	actin binding	0.0308597819321685
GO:0005856	cytoskeleton	0.0309000988926995
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	0.0372342674965943
GO:0043176	amine binding	0.0382907622951478
GO:0022829	wide pore channel activity	0.0410022296813245
GO:0005243	gap junction channel activity	0.0410022296813245
GO:0005922	connexon complex	0.0410022296813245
GO:0008092	cytoskeletal protein binding	0.0437506936400608
GO:0042401	biogenic amine biosynthetic process	0.0473077587822354
GO:0022803	passive transmembrane transporter activity	0.0473077587822354
GO:0015267	channel activity	0.0473077587822354
GO:0030054	cell junction	0.0473077587822354
GO:0016831	carboxy-lyase activity	0.0473077587822354
GO:0005921	gap junction	0.0473077587822354
GO:0042398	amino acid derivative biosynthetic process	0.0485726485829697
GO:0018958	phenol metabolic process	0.0485726485829697
GO:0006584	catecholamine metabolic process	0.0485726485829697

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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