MCL coexpression mm9:441

Phase1 CAGE Peaks

	Short description
Mm9::chr10:98724343..98724360,-	p@chr10:98724343..98724360 -
Mm9::chr11:20531724..20531728,-	p@chr11:20531724..20531728 -
Mm9::chr11:69571790..69571798,+	p@chr11:69571790..69571798 +
Mm9::chr11:87405214..87405225,-	p@chr11:87405214..87405225 -
Mm9::chr13:114584613..114584618,-	p@chr13:114584613..114584618 -
Mm9::chr15:89026611..89026618,+	p@chr15:89026611..89026618 +
Mm9::chr17:26853167..26853205,-	p@chr17:26853167..26853205 -
Mm9::chr19:53603451..53603479,-	p@chr19:53603451..53603479 -
Mm9::chr3:107949118..107949141,+	p@chr3:107949118..107949141 +
Mm9::chr4:115726172..115726197,+	p@chr4:115726172..115726197 +
Mm9::chr4:33335638..33335658,+	p@chr4:33335638..33335658 +
Mm9::chr5:122287292..122287303,+	p@chr5:122287292..122287303 +
Mm9::chr5:130732674..130732679,-	p@chr5:130732674..130732679 -
Mm9::chr5:31189981..31189985,+	p@chr5:31189981..31189985 +
Mm9::chr6:113027175..113027197,-	p1@ENSMUST00000167415
Mm9::chr7:52962498..52962512,+	p12@Dbp
Mm9::chr9:61970795..61970798,+	p@chr9:61970795..61970798 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042359	vitamin D metabolic process	0.00175313647071714
GO:0005499	vitamin D binding	0.00175313647071714
GO:0051183	vitamin transporter activity	0.00204532588250333
GO:0006775	fat-soluble vitamin metabolic process	0.00482112529447214
GO:0005496	steroid binding	0.00823974141237057
GO:0006766	vitamin metabolic process	0.00905787176537191
GO:0019842	vitamin binding	0.0131485235303786
GO:0003779	actin binding	0.0265161891195968
GO:0008092	cytoskeletal protein binding	0.0325304211788626

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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