MCL coexpression mm9:537

Phase1 CAGE Peaks

	Short description
Mm9::chr12:59313278..59313296,+	p@chr12:59313278..59313296 +
Mm9::chr15:25293506..25293560,-	p@chr15:25293506..25293560 -
Mm9::chr17:26338134..26338172,-	p2@Arhgdig
Mm9::chr19:42330304..42330357,+	p2@Golga7b
Mm9::chr19:7008681..7008708,-	p@chr19:7008681..7008708 -
Mm9::chr4:126287178..126287185,+	p4@5730409E04Rik
Mm9::chr4:126287189..126287196,+	p5@5730409E04Rik
Mm9::chr5:108796914..108796941,-	p@chr5:108796914..108796941 -
Mm9::chr5:136384758..136384876,-	p@chr5:136384758..136384876 -
Mm9::chr5:136386488..136386525,-	p@chr5:136386488..136386525 -
Mm9::chr6:38613278..38613296,+	p@chr6:38613278..38613296 +
Mm9::chr7:133991422..133991433,+	p4@Doc2a
Mm9::chr7:134165127..134165149,-	p8@Prrt2
Mm9::chr7:31836450..31836507,-	p1@Fxyd7

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005094	Rho GDP-dissociation inhibitor activity	0.0321723846106605
GO:0008047	enzyme activator activity	0.0321723846106605
GO:0005092	GDP-dissociation inhibitor activity	0.0321723846106605
GO:0004994	somatostatin receptor activity	0.0321723846106605
GO:0005080	protein kinase C binding	0.0360251744030527
GO:0007215	glutamate signaling pathway	0.0428730156033363

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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