MCL coexpression mm9:694

Phase1 CAGE Peaks

	Short description
Mm9::chr10:79819225..79819239,+	p1@Plk5
Mm9::chr11:41996015..41996022,-	p14@Gabra1
Mm9::chr11:41996032..41996041,-	p10@Gabra1
Mm9::chr16:31942578..31942582,+	p@chr16:31942578..31942582 +
Mm9::chr3:126864840..126864852,-	p20@Ank2
Mm9::chr3:33037158..33037162,-	p@chr3:33037158..33037162 -
Mm9::chr7:82453803..82453825,-	p5@Sv2b
Mm9::chr9:29219870..29219883,-	p17@Ntm
Mm9::chr9:40183917..40183943,-	p11@Gramd1b
Mm9::chr9:40183944..40184000,-	p4@Gramd1b

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007268	synaptic transmission	0.0171056100137584
GO:0019226	transmission of nerve impulse	0.0171056100137584
GO:0007267	cell-cell signaling	0.0237379267073981
GO:0030054	cell junction	0.0246834425755739
GO:0007214	gamma-aminobutyric acid signaling pathway	0.0474193736602506
GO:0004890	GABA-A receptor activity	0.0498905126945302
GO:0016917	GABA receptor activity	0.0498905126945302

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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