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MCL coexpression mm9:1145

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:97923519..97923568,-p3@Senp1
Mm9::chr3:95733202..95733221,+p1@Anp32e
Mm9::chr5:140797478..140797539,-p1@Mad1l1
Mm9::chr6:115803317..115803361,-p2@Mbd4
Mm9::chr9:13631425..13631444,-p3@Cep57
Mm9::chrX:39504179..39504196,+p7@Stag2
Mm9::chrX:39504205..39504245,+p2@Stag2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005634nucleus0.0141685794832761
GO:0016926protein desumoylation0.0314688884597356
GO:0017134fibroblast growth factor binding0.0314688884597356
GO:0007067mitosis0.0314688884597356
GO:0000087M phase of mitotic cell cycle0.0314688884597356
GO:0043231intracellular membrane-bound organelle0.0314688884597356
GO:0043227membrane-bound organelle0.0314688884597356
GO:0000278mitotic cell cycle0.0336934334272182
GO:0000279M phase0.0336934334272182
GO:0051301cell division0.0336934334272182
GO:0022403cell cycle phase0.0356650580745101
GO:0043229intracellular organelle0.0356650580745101
GO:0043226organelle0.0356650580745101
GO:0008543fibroblast growth factor receptor signaling pathway0.0411069134803286
GO:0006305DNA alkylation0.0411069134803286
GO:0006306DNA methylation0.0411069134803286
GO:0000060protein import into nucleus, translocation0.0411069134803286
GO:0008630DNA damage response, signal transduction resulting in induction of apoptosis0.0416724359350369
GO:0006284base-excision repair0.0416724359350369
GO:0006304DNA modification0.041911827250545
GO:0019212phosphatase inhibitor activity0.0421278127593552



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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