MCL coexpression mm9:1517

Phase1 CAGE Peaks

	Short description
Mm9::chr10:45206169..45206190,-	p3@Lin28b
Mm9::chr10:45206248..45206267,-	p2@Lin28b
Mm9::chr11:75263401..75263412,-	p7@Wdr81
Mm9::chr7:35754354..35754391,+	p2@Pepd
Mm9::chr7:4744775..4744787,+	p3@Gm10051 p3@Rpl28

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004251	X-Pro dipeptidase activity	0.00712211691228839
GO:0008451	X-Pro aminopeptidase activity	0.0106825900531045
GO:0016805	dipeptidase activity	0.0112711246155063
GO:0030574	collagen catabolic process	0.0112711246155063
GO:0044256	protein digestion	0.0112711246155063
GO:0044254	multicellular organismal protein catabolic process	0.0112711246155063
GO:0044266	multicellular organismal macromolecule catabolic process	0.0112711246155063
GO:0044259	multicellular organismal macromolecule metabolic process	0.0112711246155063
GO:0044243	multicellular organismal catabolic process	0.0112711246155063
GO:0044268	multicellular organismal protein metabolic process	0.0112711246155063
GO:0032963	collagen metabolic process	0.0112711246155063
GO:0044236	multicellular organismal metabolic process	0.0112711246155063
GO:0004177	aminopeptidase activity	0.0202506496729996
GO:0007586	digestion	0.020327165180066
GO:0008235	metalloexopeptidase activity	0.0260757978667363
GO:0008238	exopeptidase activity	0.0417358363055646

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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