MCL coexpression mm9:1669

Phase1 CAGE Peaks

	Short description
Mm9::chr14:75597728..75597749,+	p12@Lcp1
Mm9::chr1:67158430..67158479,+	p@chr1:67158430..67158479 +
Mm9::chr7:139768020..139768038,-	p1@Oat
Mm9::chr7:139802368..139802383,+	p2@Lhpp
Mm9::chrX:136342810..136342829,+	p@chrX:136342810..136342829 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004587	ornithine-oxo-acid transaminase activity	0.00723129172825533
GO:0042802	identical protein binding	0.00723129172825533
GO:0001891	phagocytic cup	0.00723129172825533
GO:0016338	calcium-independent cell-cell adhesion	0.0162668407931358
GO:0051017	actin filament bundle formation	0.0281850439083559
GO:0005884	actin filament	0.0365582924213738
GO:0051015	actin filament binding	0.0365582924213738
GO:0008483	transaminase activity	0.0365582924213738
GO:0001726	ruffle	0.0378956802185215
GO:0016769	transferase activity, transferring nitrogenous groups	0.0378956802185215
GO:0007015	actin filament organization	0.0393613436801453
GO:0030170	pyridoxal phosphate binding	0.0414797678200668

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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